Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SPI1 STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24429361
STAT3 SLC9A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17276988 19064501
STAT3 SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11889125
HIF1A SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934262 15780936
HIF1A NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15699159
SP1 ATP1A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24219545 15462673
SP1 CLCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12714379 10198359
DNMT1 MT1F â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16329111 12417732
NFIC SLC34A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15458926
NRF1 MT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18826952 24462598
MT1A GPR50 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218751 16778767
MT1A GPR50 â—¼   COLOCALIZATION 2.0 0.8 intact 5218751 16778767
MT1A GPR50 â—¼   PROXIMITY 2.0 0.8 intact 5218751 16778767
MTF1 SLC30A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12716893 10952993
HIF1A SP1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
NR3C1 STAT3 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
SP1 STAT3 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
HIF1A STAT3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
SP1 STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17471507 24396070 21184768 16931573
STAT3 HIF1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15735682 18985005 23604114 23991099
HIF1A SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12228247 17024177 17418410 15780936
ATOX1 ATP7A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10557326 12679332 31932435 10497213
STAT3 HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20568122 19129475
TFCP2 TF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20796026
SPI1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16263717
SP1 MT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10597227 3683394 10884303
SP1 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10919269 15664452 10845704
SP1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12039077 14962081 15249123
DNMT1 MT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16329111 22905112 12417732
NR3C1 HMOX2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ATP7B ATOX1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17919502 12968035 10557326 16573520 12763797 10497213
ATOX1 ATP7A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 23028306 22389498 26055706
NFIC MT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12426140 22228435 11444530
TRPM6 TRPM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24385424 14976260 26563869
FTL FTH1 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 8153045 21516116
ATP1A1 FXYD2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ATOX1 ATP7B â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
ATOX1 ATP7A â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
ATP1A1 ATP1B1 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
NFE2L2 HMOX1 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 10441483 10821856 10874044 11279008 11909699 12356737 12511571 15521073 16219762 17512463 18761713 19027064 19747488 23850759
NFE2L2 HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 72.0 1.0 Omnipath 24211276 21382013 23000247 21908612 17942419 18381655 31257023 12745069 22107958 18586007 23904790 24434148 21622983 21808062 22245129 16951197 22370642 23571756 24844779 21658364 11274184 20083128 14747657 15870071 17313370 24759106 20558128 14688281 23525690 21597468 22541814 21443188 21635873 18704831 22521774 16407140 22793650 18006113 22459801 24035498 24140584 23413426 22901690 18771089 24755082 20345481 16551619 23294286 23046979 15122755 16945925 23347118 23738042 21037234 23479260 19056485 19679681 22484158 18202225 24024136 16480751 19931411 20402460 17408602 21982894 25337552 24503931 19454702 23826208 20643109 18567745
HIF1A HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11592948 19828020 20819234 17389506 10600883 11356853 15805230 18799519 17122584 17996129 20526373 15050899 20833713 14970910 19254160
USF1 HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 7969144 8760880 18331200 15242350 2318208 2722866
NFE2L2 HMOX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10874044 18241676 12356737 18535259 12511571 10821856
STAT3 HIF1A â—¼   DOWN_REGULATES ✅ - 24.0 1.0 ACSN 10347215 10973499 12223527 14607900 14670306 15218058 15356132 15573129 16418395 18776941 18985005 19380816 20093776 20237412 20406969 20581311 21840487 23124025 23454751 23953057 24857661 27216177 28186502 7543512
STAT3 HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19265129 18644974 16007214 20924113 17597020 23991099
STAT3 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15870198 16861352 25854163
STAT3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15735682 18985005 10973499
HIF1A TF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19828020 9242677 12393745
FTH1 FTL â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 17603935 26653790 26794443 27048822
FTH1 FTL â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 17603935 26653790 26794443 27048822
SP1 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12706891 22734486 10446912 7478579
SP1 SLC9A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12464626 16464174 19064501 16760259 21600882 19303862 11841999 17540780
USF1 MT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9374477 9388470 9801317 11230134 10597227 9020035
NR3C1 ATP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11216640 10329476 9694812
VDR S100G â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15866228 10417310 11913978 11687634 12520535
VDR TRPV6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20227497 16574738 17556365 22563729 17293108
MTF1 MT2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9084098 11746217 12716893 17363595
MTF1 MT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8026472 18337454 18230604 8824273 10952993 11444530 12764133 21035574 16615093 9582278 14998373 8467794 10605938 14627804 16847313 11230134 12716893 12417732 15142038