Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MDM2 ATM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19816404 21986495
SP1 ATM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15837784 11466608
ATM STRAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18833288
SP1 ATP2C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15955096
STAT3 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17089128 20422978
FOXA1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16331276
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
BRCA1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 12700228
HTT CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PARP1 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 7596430 376037
CASP3 AKT1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
HTT CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16777606 10770929
CASP3 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17899380
CASP3 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18362891
HDAC3 CCND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16461912 0506281103
TP73 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16526280 22842668
CREM CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22488648 17185632
STAT3 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11279133
CCND1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11279133
SMAD7 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15023526 11180003
NFYA CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10514438 10438472
MAPK1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17205132
PIN1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11774038 16713569
CDK1 RFC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12930972
CDK2 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25558984 22231403
E2F1 HMGA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22389255
E2F1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14706452 18794899
E2F1 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20800677
E2F1 TK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067
E2F1 DLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19874716
E2F1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17707233
E2F1 HIC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19491197 19015639
E2F1 CDKN2C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22504641 12077144
E2F1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18396012
MAPK3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14967450 22802261
E2F1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9368006
E2F1 RBBP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
E2F1 MYCN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12438307 18319725
E2F1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 15867357
E2F1 CDKN2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12077144
E2F1 HIC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19491197
TBX21 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0607926103 17075044
NFKB1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
SENP3 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7941484 19680224
TP73 EP300 â—¼   ACETYLATION ✅ 2.0 0.8 intact 11804596 5215037
MAPK3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24530506
EP300 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16204234
EP300 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21988832 20089040
CTNNB1 HIC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218688 16724116
HIC1 CTNNB1 â—¼   COLOCALIZATION 2.0 0.8 intact 5218688 16724116
SP1 IFI16 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9136080 22291595
CEBPB KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23456364 17301242
TP73 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14614455 21245298
MYCN KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
NDUFV1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 TK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 NDUFV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KAT5 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24069158 12782627
LGALS3BP MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NFATC1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19661463 17239241
MYOD1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10805738 9988769
PARP1 MAPK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0508606103 16627622
PPP1CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
MAPK1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15778365
MAPK12 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9069290 9384584
ELF1 MAPK14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22139847 15246963
PML MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15273249 16189514
SYK MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12038794 8636072
MAPK3 PARP1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0508606103 16627622
PPP1CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
MAPK3 GATA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22227582 11585926
PML MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
NKX3-1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20530667 12173040
PIM1 MDM2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19166854 6823529
MDM2 PML â—¼   COLOCALIZATION 2.0 0.8 intact 5216620 12915590
PPP1CA MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23277204
MDM2 DHFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18451149
CTNNB1 MSX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12095419 15592430
MAPK8 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7033842 16982329
PIK3R1 DLX4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7642542 16982329
PIK3R1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25814554 15021914
PML STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12506013 16189514
CSNK2A1 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20711232
RCN2 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SP1 SMARCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16288722 15187086
SYK STAT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
STAT3 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17386941 31886314
STAT3 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21677772 23911788
STAT3 EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23991099
STAT3 CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22218594
PPP1CA STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19440292
STAT3 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16713569 12947115
STAT3 NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15950906
STRAP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TERT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18775701 6742757
TFAP2A TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19701232 18754863
TBP TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7666533 17967894
HNF4A TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20621834 16771709
NR1H3 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11741944 16461908
TP73 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21933882 17725714
TBX21 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24006458 21983879
TNF PSIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16403949
MYOD1 TP73 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18513743 16007124
TP73 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15737644
CRX PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19850845 18172122
TFAP2A CRX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12408971
KMT2A CDKN2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16997566
PIN1 CSNK2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11940573 5215253
PIN1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16713569 9499405
NFYC NFYB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215853 12401788
BANF1 PPP2CA â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 20711181 22770216
SMAD7 MYOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
CTNNB1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18948405 15031118
MYOD1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18094043
MYOD1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20980337 20037778
HSPA8 TNNC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA8 NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VDR NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20371119 19931640
PRKCZ NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12893839 10764587
MAP3K1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9689078 16681998
SREBF1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11875060 16480961
GATA4 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19501129 17975667
GATA6 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19501129 17463088
SMAD7 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15855641 20631490
SP1 VEGFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19147754
PIK3CA SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
SYK PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9720763 10592173
SMAD7 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15684397 1568439
PPP2CA SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20704570 23331499
MAP3K1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10085121
ZNF148 HDAC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7144461 19583777
ZNF148 HDAC3 â—¼   COLOCALIZATION 2.0 0.8 intact 7144461 19583777
ESR2 NCOR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8816459 22622808
NCOR1 SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20339114 26120082
NDUFV1 BTRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NDUFV2 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GLUD1 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPL35 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPH1 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TBX21 SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0607926103 17075044
NFKB1 TBX21 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17407192
SP1 TBX21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17705132
ESR2 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12138116 16423895
ABCB1 CAV1 â—¼   COLOCALIZATION 2.0 0.8 intact 15498565 5217256
SREBF2 SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212972 10976766
SP1 EPAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17024177 5219187
SP1 ELF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212972 10976766
SP1 SRF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10602487 10330138
SP1 HDAC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16280357
SP1 RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14742449
SP1 F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12911579
PPP2CA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24382322
SP1 CBS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14670973
PPP1CA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8288823 20186153
HTT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR2 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16549430 17261755
NFKB1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18031796
ELF1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15337760 15645134
PRKCZ AKT1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18650932 7232391
PPP1CA AKT1 â—¼   COLOCALIZATION 2.0 0.8 intact 8288823 20186153
PPP1CA AKT1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288823 20186153
MAPK8 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16306447
GATA4 MEF2C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15843409 15253934
MEF2C CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24473123 18758483
HDAC4 MEF2C â—¼   COLOCALIZATION 2.0 0.8 intact 5215014 11792813
NFKB1 MAT2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14530285
NFKB1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19027835
NFKB1 LPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20200316
NFKB1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21790895
PRKCZ NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11684013 12881425
CTNNB1 LMO2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592430 12782598
CDK4 CCND2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
PRKCZ VHL â—¼   COLOCALIZATION 2.0 0.8 intact 5219754 17350623
PRKCZ MAPK10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18667433 17646398
PRKCZ MAPK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18667433 17646398
CTNNB1 VHL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16983094 0606850103
CEBPB NFYA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21150337 9019155
CEBPB CPT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20627112 21586575
CEBPB MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9743233 22139077
CEBPB SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22355693
ZNF148 HDAC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7144461 19583777
PPP2CA HDAC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18045992
TPI1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP1CA HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP7 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MT2A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT SREBF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
HTT CBS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT RPS19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TFAP2A HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11483245
PPP2CA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10644691 19061640
TFAP2A CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7739559
ZBTB7A CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14701838 18368381
CTNNB1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16219695
CTNNB1 CBS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 BTRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15473860 10882123
VDR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11470825 23331499
HSPA8 PSIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NR1H3 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17054913 22279938
NR1H3 APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17026988 11035776
PSIP1 HSPB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11350077
TBP FOXA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17495528 14675539
HNF4A TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19805548
TBP MAPK9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17074809 19620725
TBP MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17074809 19620725
TBP SUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9512709 9792714
CHD3 HSPH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NFATC1 F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19460777 19351910
PIM1 NFATC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28235034 11823475
SREBF2 HNF4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12855700 5216527
GATA6 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11585914 9832509
HNF4A F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12911579
MT2A MAT2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NFYC NFYA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12857858 22969033
SRF GATA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11003651 11158291
VDR ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18602086 19460946
TFAP2A FOXA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24835590 22577344
TFAP2A DLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23085542 17549389
TFAP2A IVL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12192491 9219563
TFAP2A HOXA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8759021
SREBF1 COL6A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14697233 23221806
GATA6 FABP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16603485 14715527
HSD17B4 COL6A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCNA2 PCNA â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
F2 FGG â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CCND1 CDK1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
MAPK8 MAPK9 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
APC BTRC â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
CDK1 CCNA1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 7799941 1628647 14681455 8565853 16009130
NFKB1 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11739381 23811396 14662860 12471036 20065107 22013068 12960163
EP300 PARP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18280497 16204234 19622798 12960163 24636898 33742100
AKT1 MDM2 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
MDM2 AKT1 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
HNF4A SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15651981 16713569 19115260
NCOR1 VDR â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
VHL ATM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 16678111
HSPB1 CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 30669930
CDK2 CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 21319273
CDK2 NFYA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24407240 12857729
VHL DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 21942715
DDX5 CHD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28977666 20676135
EPAS1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23275444 15261140 22807441 25689462
NR1H3 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25962847 33742100
SMAD2 KAT2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22995475 15009097 11058129 34576109
SP1 KAT2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16050810 15647279
NFYA KAT2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15647279 16959611
NFKB1 PRKDC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14743216 25609649
SP1 EPAS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22402494 17024177
NFYC NFKB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SP2 NFYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 35140242
NFYC PON1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NFYA BRCA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11777930 16713569
CASP3 MDM2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25241761 9278461 24842904 9840926 21726810
CASP3 PARP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19549685 32223133 8642305 7596430 19713971 22451931 17167422 9875225 18723680
CCND1 RFC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10353443 21654808
CCND1 CDK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26496610 33961781 7903056 21654808
ESR2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11500849 18765668
NFYB EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10075648 9799238 15454570
CCNA2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
EP300 STRAP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30110629 18451878 33742100
HSPB1 HSF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25036637 19597476
KAT5 STAT3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12551922 16713569
MAPK3 HSPB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25241761 21575178 8774846
SP1 MSX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10215616 16713569
TAF4 SP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11988536 9742090
NCOR1 ESR2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29509190 12904255
CCNA2 CCNA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
AKT1 MAPK14 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CDK1 CDC25C â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 8119945
CDC25C CDK1 â—¼   DEPHOSPHORYLATION ✅ + 0.83 0.83 Signor 19574738
AKT1 BRCA1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CCND1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
EP300 VHL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
GNL3 MDM2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KAT5 MDM2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
BRCA1 CDK2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
KAT2B MDM2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PARP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 25252691 26831064
PRKDC BRCA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10608806 25223785
HCFC1 E2F1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17612494 20622854
PRKDC PARP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16794079 9398855 21575865 20085707
SP1 STAT3 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
STRAP SMAD7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17314099 10757800
PCNA CCNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 7903056 33961781 8101826
CEBPB SP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16651265 12847250 12665574
APOA1 APOB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28183703 7592581 19164805
CSNK2A1 PML â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
HDAC3 STAT3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
CCND1 STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11279133 15659654
SENP3 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19680224 15632193 22684029
MEF2C EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21556048 9001254
EP300 PRKDC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
PIN1 PML â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22033920 18039859 21840486 20100838 24586174
TBP RNF4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9710597 11696545
SP1 STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17471507 24396070 21184768 16931573
APOA1 APOA2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10722751 24981860 3104518
RORA MYOD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9862959 16713569
HDAC3 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29523594 20026773
RBBP4 SP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16713569 12091390 12943729
MYCN SP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18003922 21123453 20697349
ELF1 NFKB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9094628 7862168
TBP CREM â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10409662 16713569
CEBPB EP300 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
E2F1 EP300 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ATM PRKDC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10608806 10464290
BRCA1 RFC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 25184681 10783165
BRCA1 CCNA1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 9244350 10373534
KAT2B CCND1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11328859 10318892
PURA E2F1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15517862 10597240
EP300 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10205054 15653507 16713569 33531691 26504087 18782771 30110629 11923478 15735682 15649887 33742100 22116549
TBP HSF1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11005381 16713569
PIM1 MDM2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19166854 18467333
PCNA PARP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20129057 20302655 12930846 21690293 20303835
RNF4 SP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34550526 10617653 21983342 26511642
AKT1 SMAD2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16362038 24412244
HDAC4 RBBP4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31040226 10220385
AKT1 PRKCZ â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CCNA1 CDK1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CCNA2 BRCA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25091198 16713569 9244350 10373534
CDK4 BRCA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17334399 16713569 9244350 12509456
SP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14710355 16713569 12706836 10720440 17766039
CCND2 CDK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9840943 28514442 33854235 33961781 26186194 23455922 9178893
KAT2B E2F1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24502362 23001041 35140242 19188449 24112038 15123636
GATA4 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18252717 27208796 11481322
AKT1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21901101 15224190 21775285 20333651 18182168 11116148
KAT2B MYOD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20364308 9659901 27453350 17964260 10944526 10619020 12887892 17468105
TBP MDM2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9388200 16713569 9271120
PARP1 NFKB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16204234 11590148 25609649 16799643
MYOD1 NCOR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 10406466
HDAC3 RBBP4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11777905 16189514 11470869
KLF10 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15087465 10976766
CEBPB CEBPD â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 1840554 20102225
MDM2 PML â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EP300 STAT3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 NAP1L1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HSF1 HSPA4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MAP3K1 MAPK1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 NFKB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MAPK1 MAPK14 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
NCOR1 PGR â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BAP1 HCFC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ATM BRCA1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CASP3 MDM2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
EP300 TP73 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BTRC NFKB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
BRCA1 RPA1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
EP300 CCND1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15951563 10567390 11788592
CCNA1 E2F1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16774918 10022926
SP1 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15647279 19062177 10651903 11517158 23714681 10899165 16478997 11030335 24530506 34252870 28425985 31536933 32115405 17623675 10362258 16734381 17906698 22415975 12200149
EP300 SMAD2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11371641 21988832 10199400 12237408 11264182 15623506
EP300 VDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32603375 15647825 20089040 21988832
EP300 RORA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9862959 16713569
DNMT1 PARP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 27728808 23708667
STAT3 PML â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12506013 16189514
PML HDAC3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 11259576
AKT1 PRKDC â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15678105 15262962
NFKB1 SFPQ â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22536447 14743216
MYOD1 STAT3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12947115 16713569
PIN1 SMAD2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19920136 19122240
TBP NFYB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 9153318
SRF MYOG â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10082523 8617811
MYOD1 CDK4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10601020 10022835
SMAD2 SP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11114293 10878024 22227581
NR1H3 NCOR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12663743 26120082 15604093 33961781
SP1 NFKB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18083845 16740634 33572115 7933095
GATA4 SRF â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11158291 11003651
PML RNF4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
AKT1 PIK3CA â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CASP3 PARP1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 MYOD1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
HSPA8 HSPH1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
MAP3K1 MAPK8 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
STAT3 SYK â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
BTRC CTNNB1 â—¼   UBIQUITINATION ✅ - 0.88 0.88 Signor 10228155
CDKN2C CRX â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
AKT1 PPP2CA â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
RBBP4 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10220405 16713569 26831064
CCNB1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 11278247 23246971 9244350
BAP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9528852 23850490 16713569
CCND1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17334399 16713569 9244350
HDAC3 CCND1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15713663 12048199 16461912 20484017 15558026
CDK1 CCNA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24302728 21308745 26496610 33422522 14681455 23602568 25852190 33961781 12853968 26186194 17679094 32707033 9053846 8463339 19483727
E2F1 CDK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8458319 7969176 9199321 1530885 11245432
PARP1 E2F1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20133863 14627987
KAT2B EP300 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8684459 12888487 9267036 12419806 21413932 22384255 20870727 33051058
KAT2B MYOD1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MAPK1 STAT3 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
TBP MSX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8700832 10215616 16713569 9111364
RNF4 PML â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29180619 19380586 24907272 15707587 23028697 18408734 21252943 18708055 24637324 22388745
AKT1 TERT â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28628118 15843522 28205554 10224060 18775701
CCNA2 PCNA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 12853968 26186194 10930425
CDK4 PCNA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 8259215 11254741 8101826
PCNA DNMT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20940144 20613874 24958773 9302295 26496610 30301766 12354094 23708667 22606318 10888872
NCOR1 VDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9878542 19098224 11124027 16252006 12460926 10877839
HMGA1 SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20335021 12665574
AKT1 HSPB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17510053 31980649 12740362 11042204 23397142
PPP1R13L PPP1CA â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 21998301 270751 8217559
CHD3 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28977666 27705803 33961781 24981860 22939629 9885572
PIN1 ZBTB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
PPP1CA PPP1R13L â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CCNA2 E2F1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CDK4 CDKN2C â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC4 MEF2C â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
APC CASP3 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 10200466 17297457 9973322
RPA1 ATM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
ATM BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11114888 11278964 29656893 10783165 11016625 10866324 10550055 15713674 18344987 10608806 17478428
E2F1 ATM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22832221 23993922 12527885
KAT5 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16141325
ATM AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15546863 15899889
BRCA1 BACH1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17664283 15208681 16713569 19369211 17525340 15125843 15242590 16391231 25252691 11301010 11877378
EP300 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 19887647 10655477 11782371 16713569 21212407 22787115
AKT1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21242970 10542266 20085797 19074868
CDK2 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31270457 16713569 10373534 9244350 8764100
DNMT1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19943104 22197621 20631324
CASP3 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12149654
VDR CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18832097 18259074
CASP3 RFC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9235961 9351817
CASP3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9348292
CASP3 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9367996 29752472
CCND1 CDK2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
PCNA CCND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15681588 7908906 8101826 33961781 7903056 21654808
CCND1 TFDP2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
CEBPB CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22242598 11162569 12810706
CCNB1 CDK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 34224728 18337751 9891079 24508230 17431037 9560267 14681455 17283331 8662825 19162005 16159883 25852190 20360007 19879842 12397081 11331587 9247342 26496610 20228808 25750436 12612082 16784539 23602568 20733055 27626412 20367638 8397206 10973963 9001210 20956543 33037310 8397207 23543736 32707033 2570636 30674583 10716937 27030811 18408765 24358021 20974803 7799941 33961781 26186194 17679094 23799914 8463339 26344197
CDK1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17477081 23526763 21840486
CDK2 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 26186194 10330164 23455922
PCNA CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10930425
CDK2 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11598016 19450264
ESR2 CLU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
DDX5 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 33742100 12527917
EP300 DDX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12527917 20663877
E2F1 CCNA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8458319 7969176 12501191 35140242 9724724
HCFC1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17612494 19763085 23629655
E2F1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10914734 20837136
E2F1 DNMT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24502362 17575144 15867357
E2F1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20639906 16835303
EP300 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10753885 15123636 15126619
SP1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10547281 8657141 10850422
E2F1 DHFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11564866 8441401 18319725
EP300 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15154850 20234175 16713569 11070080 9809062 28196907 15013777
EP300 CEBPB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28428115 9343424 14630807 12471036
EP300 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11268218 16713569 18263614 12937166 24939902 14988403 33742100
EP300 MYOD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20364308 12665587 20037778 17964260 35140242 10944526 9862959 9001254 8621548
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
EP300 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11796223 11062529 9001254
GNL3 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24769896 18426907 19033382 21132010
HSF1 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12919958 9325337
KAT2B MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21209460 21060154 32404984 14769800 12068014 28286521
RPA1 KAT5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
KAT5 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18499675 11927554 18264029 19150978
MDM2 KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11927554 16904321
MEF2C MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9069290 17210568 9988769
PPP1CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
PPP2CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MAPK1 GATA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11585926
MAPK1 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19941816
PPP2CA MAPK3 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MAPK3 PPP1CA â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MAPK3 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15093545
MAPK3 SCNN1G â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11805112
AKT1 MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
MDM2 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22869143 16713569 12915590 23169665 14507915 19150978 20972456 15195100 12759344
PPP2CA MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983168
PRKDC MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17570479 22444248 10721693
TK1 MKI67 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MSX1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15192231 10529415 7664340
SP1 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16814105 19464346 17376651
SP1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9819401 21360626 24728382 16713569
NCOR1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11430826 10882117 16713569
PML SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15356634
PRKDC PDX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16166097
RPA1 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SFPQ PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15668243 19339282 19423654
NFKB1 STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12057007 25241761 16713569
STAT3 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24287565 12147685
STAT3 ESR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23295773 21546410
STAT3 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20830236
STAT3 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16527988 14715258
STAT3 PIM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 11533249
SMAD2 STRAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10757800
STRAP SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10757800
TBP TAF4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8858156 19240132 9603525 10373431 9674425 9153318 22323595 22939629 17967894 12665565 9311784
TERT CTNNB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19571879 11532957 21654818
PIN1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15175157 16713569
DEAF1 PIN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKCZ PIN1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
NFYB NFYA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 25416956 12857729 23332751 26496610 14681455 8051128 26344197 15243141 15831478 17098936 16959611
EPAS1 CA9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20061373 12171890
MYOD1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10973962 16901893 21689744
DLX4 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19664474 17456765 16598437
SMAD2 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11486006 15188178 18952601
CTNNB1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16288908 18952601 12810642
KLF10 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22234868 12173049 12244575
SP1 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16714330 10843994
SMAD7 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 16571110
HDAC3 HDAC4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31040226 10220385 10869435 11466315 11804585 17956988 27684187 18558095
HDAC3 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12150997 15811852 15494311
HDAC4 NCOR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31040226 23752268 16713569 10640275 10860984 11804585 17956988 27684187
AKT1 NCOR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23940660
HCFC1 SP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 12670868 10976766
SP1 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10919269 15664452 10845704
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
SP1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20427719 20538607 9151857
SP1 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14561739 16452190 9295358
SP1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10849443 19027835
SP1 CREM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21757709 21097497 22281835
SP1 HDAC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18632985 18850004
HDAC4 MEF2C â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31040226 23752268 32296183 15743821 15964851 12709441 10523670 11504882 11792813 18332106 11486037 11279209
NFKB1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18234965 12527911 19763573
NFKB1 CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24296733 18425349
CDK4 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDK4 TFDP2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
SRF CEBPB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9032301 11500490 10318842
MAPK10 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20220133
PPP2CA ELF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18714041
PIM1 RPS19 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16266891
CCND2 TFDP2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
BAP1 HCFC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22683710 20805357 21642991 24703950 24211834 27705803 34591877 19188440 33961781 19815555 26416890 32509391 30463901 19615732
CTNNB1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15592430 10987283 12154096
CTNNB1 HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12944908 25241761
HSPA8 MAPK8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NR1H3 DHCR24 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18815215 23359226 23416078
MAPK8 NFATC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16648474 10978313 11274345
MAPK9 NFATC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16648474 10978313 11274345
HNF4A F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12911579 24038112
HNF4A NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17317687 11741883 16479620
ESR2 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15664452 17088408 17556531
RBBP4 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
VDR APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18082637 21062631 16236546
GATA6 APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14659877
TFAP2A CGA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10648798 11014230
SREBF2 CASP7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19323650
SREBF1 CASP7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19323650
TK1 DEAF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TFAP2A LPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18948972 16890192 17549389
SREBF1 LPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9788252 18974273 11090277
CCND2 CDK2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CSNK2A1 OGT â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
HDAC4 NCOR1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
HSPA4 HSPA8 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
HDAC3 HDAC4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
MDM2 USP7 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
BTRC NFKBIA â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CCNA2 CDK1 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
SP1 NFYA â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 30392062 10393239 15647279 10446910
CTNNB1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218183 16376880
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CCNA1 CDK2 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
KMT2A PSIP1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CHD3 RBBP4 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CCND2 CDK4 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
CTNNB1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 36950384
CCND1 CDK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9840943 28514442 8647086 33854235 8479754 26496610 33854239 33961781 23455922 21654808 9178893
CCNB1 CDK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 20733051 28514442 9891079 7799941 8397207 25852190 26496610 33961781 26186194 23602568 10995390 23455922 30674583 18471975
PCNA CDK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12361598 28514442 26496610 29510343 9545286 33961781 26186194 7903056 21319273 10930425
E2F1 SP1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10850422 10409740 8657141 10547281 8657142
AKT1 MDM2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32450252 25241761 18332867 12145204 19166854 15527798 20856200 11715018 23397142 11504915 11923280 21930127
EPAS1 VHL â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 17967880 26735578 10823831 30487161 26342197 11331613 12604794 15611064 10353251 21685897 28775317 17339318 25500545 23401859 17986458 33591636 10878807 11292862 24981860
PPP6C PPP6R3 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
PPP2CA PPP2R4 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
TFDP2 E2F1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 7739537 9501179 9704927 35140242 9368098 8755520 26186194 33961781
USP7 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6799761 18566590
PIK3R1 PIK3CA â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20018188 7383613
PCNA RFC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12171929 12192049 22939629 9649448 15225546 24958773 12045192 26496610 10353443 8861969 30301766 9092549 8999859 12400013 26344197
NFYC NFYB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 21988832 26496610 35140242 33961781 20936779 9388234 12401788 26344197
HDAC3 NCOR1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16917504 11466315 10944117 21258344 11509652 16195251 16469706 14722073 15601853 12628926 11931768 11804585 14527417 16980585 23752268 29523594 16713569 10860984 11013263
NFYC NFYA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 12857729 14681455 35140242 33961781 20936779 26186194 15243141 26344197 23332751
HCFC1 OGT â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
DNMT1 PCNA â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CDK2 CCNA2 â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 10652300
DNMT1 USP7 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CDK4 PCNA â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CCNB1 CDK2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
MDM2 TP73 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RPS15 RPSA â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
NFKB1 NFKBIA â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RPL35 RPS15 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
CCND1 CDK4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 25416956 25241761 8259215 9372967 29142209 9150368 18537972 16431923 33854235 24292678 9178893 33854239 9106657 14681455 8867812 8662825 17420273 19767775 16985050 19075005 12519773 21306487 26203195 24855949 23007395 11360184 10580009 11463845 17081987 8978686 16613857 15681588 21242975 15232106 9837900 24218572 27130439 10022865 25910212 9228064 12036906 23707388 23543736 27107012 23718855 19470470 31217276 10908655 8756624 25502805 17205132 33961781 20837141 19237565 21654808 11160398 7568034
CCNA2 CDK2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 8475101 28514442 16431923 33854235 11940657 10559988 15189033 17361108 16290148 14681455 17254966 8662825 25852190 15557281 23455922 19483727 18471975 11141566 10924145 15828833 21241890 19631451 11377199 18177895 8684460 26496610 9716181 12853968 11907280 23602568 9724724 15647383 14656438 19773423 12941338 15239650 24302728 25669885 15890360 7630397 8756328 8397207 21447625 22231403 20733051 9660939 24358021 12044161 33422522 11983168 33961781 26186194 7553852 16209941 12244298 9380407 8463339 15455144 10930425
CCND2 CDK4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 16189514 14681455 32296183 9325318 11360184 30217970 28205554 15169570 10022865 17873913 25910212 27107012 28628118 33961781 26186194 11896535 9178893 11971966
RPL35 RPSA â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
CDK2 PCNA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PCNA RPA1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
EPAS1 VHL â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
TAF4 TBP â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPS19 RPSA â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PCNA RFC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NFYA NFYB â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NFYA NFYC â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL35 RPS19 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCND1 CDK4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NFYB NFYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NDUFV1 NDUFV2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS15 RPS19 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BTRC CTNNB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
APC CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
PPP2CA APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10698523
APC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 10545404 11166179 8259519 7890674 22083140 27902311 8638126 16212417 16798748 19061640 9286858 15327769 9482734 11533658 22056988 19576224 15327768 17318191 26496610 12628243 15355978 9065403 11712088 25241761 26910375 22682247 9065401 12000790 11707392 20219694 9707618 23840886 15525529 11251183 8628279 19631635 11972058 21664290
BRCA1 ATM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
CDK2 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9781043 16322221 16123081 11292842 10928988
ATM BRCA1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM PARP1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM MDM2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
PPP2CA ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15510216
ATM SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23148884 18619531 22826432 27156884 29144413 29294106 23046908 17609267 18171990
ATM E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 20972224 11459832 27679857 15494392 15140942 27028861 21543892 27025900 20860841 24741006 17570479 25101673 28812991 15838517 22174788
ATM EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20471956 15494392 15140942 29590107 26170237 21108945 15838517 27220480
ATM HMGA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17570479 20123066 17525332 21339738 18783938
ATM RPA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17525332 11359916
ATM PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17189255 12231622 17303408 24492479 10464290 22230547 15677476 16822724 28985363 29088817 16163361 32868446 19549901 25818648 22923485 19103741 17570479 27939942 19808981 23847781 22355272 24714417 15964794 21376743 31983282 25224041 16908529 12607003 19244120 17525332 15459660 34249431 28107384 12186630 25714019 11877377 26553138 27568553 19535303 15507430 26578593
ATM MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 66.0 1.0 Omnipath 14654783 12383858 17936559 20651945 17303408 19816404 10611322 23150762 23277204 23386996 26416444 27258263 23002429 11331603 15865937 21556066 16163361 23708100 17570479 20514355 22264782 27177180 18265945 28690977 23847781 22264786 15140942 15964794 19788416 22624716 25201202 27462439 12607003 28050229 32350255 22649771 27956626 15459660 22976441 25247188 28904407 11877377 21859827 24534650 23405218 29290977 27568562
ATM BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 26927092 17303408 15159397 24746700 12024016 10866324 30197789 12919958 11114888 26745677 26383678 34301763 12427729 11313470 16163361 28035057 20068231 25939603 26320175 17570479 19683496 22743550 10608806 23802008 23847781 21203981 15964794 12183412 12607003 17525332 19996295 15459660 11278964 19651622 21706030 11877377 20952512 10373534 19622773 10550055 27170701 15212693 23704879
ATM ZNF148 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17560543
PRKCZ BAX â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10873802 10934475 10954424 14766748 15642728 17525161 20505164
NFKB1 BAX â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 12676992 15613549 21725609 23178297 23572150 7834749
TP73 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18034190 17346710 18421303 21245298 10559267 18418051 18644986 17521288 19067706 11748232
E2F1 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9748148 11095619 12370749 14514686 15255934
SP1 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11278953 10510469 11748232
NKX3-1 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12203124 17213822 19801665 8183578 21594902 17486276 23291169 19266349 19242108 19054058 19136938
MAPK8 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15525785 18471544 16709574
AKT1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 26763134 14766748 15642728 17525161
PRKCZ BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16679323 14766748 15642728 17525161
PCNA BRCA1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 E2F1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 SFPQ â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 PARP1 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PCNA BRCA1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 E2F1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 PARP1 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 SFPQ â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 E2F1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
SP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15252835 17373631 18377656 19466541
E2F1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10660629 23285190 18660752 19466541 17106239 20068145 23108140
BAP1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16713569 9528852
E2F1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9244350 18660752 18319725 11278247 12697828 16713569 12909625
CDK2 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8764100 10373534 10550055 19683496 16713569 26719576 15212693
AKT1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17428466 20832017 20085797 21242970 17570479 10542266
CDK1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9244350 21706030 10550055 17570479 19683496 16713569 26745677 32193285 26719576
CDK4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9244350 16713569 17334399 20932174
PPP1CA BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 25056273 12438214 17511879 17603999
NKX3-1 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21850191 15705778 24961145 20599703
E2F1 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18660752 12389032 18319725
MAPK14 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 14970175 33176141 29414778
CASP3 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25241761 9278461 21726810 24842904 9840926
CASP3 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11907276 8090205 7596430 9875225 32223133 10438458 17167422 7774019
CASP3 PSIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12181742 18708362
CASP3 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8798786 12867423 8670824 8804412
CASP3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17544405 12124386 10579725
NFKB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17673602 10464245 18566231 18341653 11861406 20103608 12894581 17098279 22306268 10409765 19766095 15756023 17407600 18184402 17944672 17008396 15856023 20538607 19263436 16453001
SP1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 10497251 22911796 19850937 9236224 17617380 9407106 15870300 22415074 10850422 9584162 10908361 22734486 16267018 9637785 19755513 11410592 11024050 15922873 12794082 20435036 22334592
ESR2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15313930 14764652 18607069 23891847 11986316 18223478 14729654
PGR CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22396492 22892083 15282324 20479568 22542550
E2F1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10504464 7929342 22768064 19876926 20220142 9584162 17998543 20655656 8618861 8137237 23078099 23543735 10594784
STAT3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 16510571 19880237 17997399 15469392 16651438 21163886 22566696 16912181 22349830 16384639 12147685 21344490 20160059 19506034 20332458 23329648 11114718 17761947 22218594 15994929 21172343 18988190 18177723 24499623 21435102 19926637 18184402 17344214 22313388 23950841
CTNNB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16628468 10318916 12095419 15111320 15735151 18679417 17360646 12782598 10201372 14557550 19778454 20300972 19662654 12589056 11943708 10915780 17693601 15592430 17109766
EP300 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17306568 17666529 11788592 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
CTNNB1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 19751508 10318916 7542250 11967263 22290435 11836555 19623618 12663502 23343194 11955436 22270359 22761862 16039586 15810077 10201372 19020303 17143292 12051714 17208333 8666229 18974774 16940750 14712077 17666529 21285352 19619488 15377999
CCND1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 26203195 17145710 8978686 12036906 23562856 25416956 16985050 23707388 19767775 9837900 17517622 19237565 9372967 25502805 23718855 9228064 7736585 15232106 11360184 20837141 21306487 25910212 25241761 27107012 9150368 18537972 9178893 31217276 8867812 10580009 23007395 11160398 19470470 19075005 9106657 8259215 10908655 8756624 23543736 24855949 7568034 24218572 8662825 31515488 17205132
CCND1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK1 E2F1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14551205 15279786 17218262 17303408 17660363 18414028 18590585 7575488
CDK1 CDC25C â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 1075565 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17568790 17596790 17660363 18073536 18414028 18543256 18590585 18786381 18995830 19652693 19686080 7575488 9892021
CDK1 RPA1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 7575488
TP73 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19861536 11593387 19067706
E2F1 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15510213 7623816 14618416 12760745 11799067 8137237 12629169 17108174
CCNA2 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 1833185 10924145 8423786
CDK1 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12202491 17145710 17274640 22367880 18088087 17202132 9122166 97225924 10880350
CDK1 SREBF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16880739
CDK1 KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 21658600 12468530 16103124 17570479 26829474 18669648
CDK1 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 7592773 30392930 18691976 19387552 20068231 96029687 16371510 1400350 19941816
CDK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25398907 28831131 20150555 22266860
CDK1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 21902831 10942602 17014844 10082583 10764802 9710583 14749395
CDK1 HMGA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 17081983 20068230 17924679 17960875 20068231 2168176 17570479 1939057 19413330 20123066 19664995 18669648 15302935
CDK1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 7575488 18590585 17303408 8087847 27175585 17570479 17660363 15279786
CDK1 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17349584 17110335 17303408 18073536 1075565 11836499 15279786 8348613 7575488 20668692 24710276 9733650 12036951 20068231 8440392 12742231 32075732 16189514 9141461 16123593 18669648 19652693 18590585 9585407 12814430 10864927 10373560 18691976 11313986 12124778 18786381 17660363 18272572 8119945 15917306 27038604 9268380 17596790 28396830 17568790 19350548 16964243 10037602 18212344 12478465 12766774
CDK1 TK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 20068231 9575153 19413330 12435275 14697231
CDK1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15985436 17620410 12676926
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
CDK1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21565170 27220480
CCNA2 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CCNA1 CDK2 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 16189514 15583032 25241761 16777603 10559988 14681455 9636170 16159883 9041194 10652300 8565853 12970441 14701826 8397206 14681231 11264176 8397207 15601848 12191604 12190313 7799941 19423708 12800980 16009130
CDK2 E2F1 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 12086603 14536078 14988723 15136767 15147722 15175241 15279786 15798197 16713580 16805667 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18469862 18590585 18636226 18995830 19282663 19342888 19622404 19793801 20051983 7575488
CDK2 RPA1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
MAPK1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10962581 12359725
AKT1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18354084 29665367
CDK2 TK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 25003822 12435275 14697231 9575153
CDK2 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21565170
CDK2 HMGA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17960875 17570479 21319273
CDK2 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17601773 22369944 17570479 20818427
CDK2 PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 43.0 1.0 Omnipath 8662865 15572662 17717077 26577046 7476977 20116396 24291072 10628747 24333793 11509655 21945472 21447625 29301281 27852068 25252652 22809143 18202149 18088087 15798179 19118566 9171245 10655479 11110801 15601848 28412963 19706513 22697792 12529413 15212693 19904813 24302725
CDK2 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22002055 15985436 12676926
CDK2 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12202491 17145710 14715909 17274640 16550609 18088087 17570479 9122166 97225924 15212693 10880350
CDK2 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20530684 28396830
CDK2 NFYA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20068231 18669648 12857729
CDK2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 7575488 18590585 9315635 17303408 17570479 25101673 16213134 17660363 12006580 11420722 15279786
CDK2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 81.0 1.0 Omnipath 8756328 7553852 11377199 17145710 23602568 11983168 12044161 19483727 12853968 16209941 8397207 15455144 19631451 8475101 24358021 15557281 8684460 12941338 15647383 15890360 21447625 9380407 26496610 11141566 25852190 15189033 14656438 20733051 21241890 10652300 25669885 12244298 26186194 10930425 9660939 10477583 24302728 15239650 19773423 8463339 16290148 10924145 11907280 17361108 17254966 8662825 15828833 18471975 9724724 7630397 10559988 9716181 11940657 23455922
CDK2 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 21902831 10942602 25751651 25552934 22179841 17570479 10082583 26825227 10764802 9710583
CLU LRP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 32332780 17260971 7768901 16713569
DDX5 FOXA1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17495528 15343269 19718048 11682626 28539435 14675539
SP1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9054613 12697671 10446910 18440323
E2F1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21411498 22654424 18818403 11433024 19358274 22207128 16264179 12368233
E2F1 DHFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8441401 14618416 8816912 20580656 7494286 12565705 10597240 15481443 9096302 9819401 10336493
E2F1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 7623816 12782299 14618416 20580656 9389735 11133765 8903355 9649317 23078099 12468739 1261188
E2F1 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7623816 11264255 9178900 20580656 14681231 10594784 24335704
E2F1 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12438307 16931907 14645238
E2F1 TP73 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12766778 11101847 11988839 14602923 18660752 19188449 18029729 18521084 15210709 11115495 17980704 19363520 12789260 21310950 22952705
TFDP2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 26186194 9704927 9368098 8755520 9501179 7739537
PARP1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14627987 20133863
CCND2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CCNA2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15840440 16135794 9736735 15133492 15558010 15123636 9556498 12501191 16213134 11980909 16123593
CDK4 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CCNA1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17660363 15840440 16135794 18590585 7575488 17303408 9736735 15133492 15558010 15123636 9556498 10022926 16213134 11980909 16123593 11739724 15279786
E2F1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15210709 11988839 17488475 11937641
E2F1 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18660752 12389032 18319725
E2F1 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15510213 18319725 11491305
E2F1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15510213 7575488 18590585 17303408 18319725 17660363 15279786
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
SENP3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15632193 19680224
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
EP300 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10944526 9001254
EP300 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 21988832 23331499 9169454 12237408 10199400 11264182 7878020 8047140 12958365 19171760 11371641 16027720 17074756 17469772 21269274 15623506
EP300 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18782771 15509516 8756628 10205054 7530500 15653507 15735682 19506034 16285960 16713569 11322950 7499365 15649887 9590694
EP300 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 11804596 19407812 15175157 19788416 12660246 19218448 10648616 15454570 16998810 25675294 15893728 18663001
EP300 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
EP300 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 12408818 10887155 15831498 21269274
HSF1 HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 12064483 23733891 8078944 9738016 21078672 9276725 18197143 20566634 8455624 8035809 9880553 19818013 14673132 18451878 9665826 15777846 22940245 9499401 9482883 7553870 1508207 22797943 25053922 12805380 18657505 16447264 21932106 23349863 10440232 12007842 16554822 8114740 12782657 23264262 12813038 23542779 25024384
MAPK3 HSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 53.0 1.0 Omnipath 17081983 20166139 34363019 26359349 22768106 24516381 24126052 19413330 15302935 28618124 30138434 10747973 27639166 27997575 20068231 31614463 12917326 8940068 18669648 27105490 26340096 27605553 25752395 27487129 9121459 25406061 33461973 27354066 19651622 31657478 31940498 26010766 32959058 33268814 19664994 22172248 24954509 27791982 18212344 25024384
CSNK2A1 HSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12659875 15302935
MAPK8 HSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 19651622 17081983 10747973 20166139 18767875 20068231 18669648
CSNK2A1 IFI16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11115400
SP1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20130956 20144149 17882273 15647279
KAT2B MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 9659901 10944526 10619020
KAT2B SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 34576109 17074756 11058129
KAT2B TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11804596 19407812 19788416 12660246 14614455 18663001
CTNNB1 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9843967 14695187 16510874 15829968 11080158
PML KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19150978
KAT5 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16603769 16904321
KAT5 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12551922 16713569
MAPK1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
SP1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12220517 16797880 20506264 20121399 20882567 18372343 10727414 21170990 17889508
MAP3K1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 10969079 15315965 17052767 12049732 11971971
PPP2CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 10592173 7780739 18588945 2154696 20626350
MAPK14 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15187187 21675959 18039929 12738796 11157753 22521293 17255949 11238443 11274345 12697810
PRKCZ MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
MAPK13 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16009338 12213825 8384717 10995751 12048245 15878863 21980398 19443782 17570479 19413330 19723873 15367685
MAPK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19318349 20882567 16377629 18775330 8226933 14744793 16079281 11904305 9604935 15212693 14593115 8388392
MAPK1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 23331499 10197981 34504019 18775330 20659902 8226933 9620846 16156666 9604935 18988627 12193595 11027280 8388392 27153775 31995604
MAPK1 PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 8702648 17173941 18202149 10628747 15798179 17717077 12529413 15212693 10655479 11110801
MAPK1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 59.0 1.0 Omnipath 18448488 19413330 11335711 9343414 15465816 25584415 12576423 11350938 20068231 12681450 12763138 9872331 11780390 18491316 18669648 11404481 10521505 18691976 20058876 15979846 14551213 10446219
MAPK1 SREBF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10627507 10915800 18669648
MAPK1 SCNN1G â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11805112
MAPK1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22935031 29416846 23293771 23316480 15093545
MAPK1 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23597856 26637332 16627622
MAPK1 RORA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17512500
MAPK1 SREBF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10627507 14988395
MAPK12 MEF2C â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10805738 9988769 9069290 9858528 10330143
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK14 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14580335 16410802 8622692 8668171 9724653
MAPK14 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 10201984 18691976 17502367 17570479
MAPK14 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 21902831 9069290 23331499 9858528 9384584 10330143 9753748 10805738 16189514 18988627 26660426
MAPK14 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 15150265 10744722 9836640 9543386 12941695 20068231 9278512 10681541 16189514 15791647 11551930 9278511 11333986 15629715 10557092
MAPK14 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17486076 27843138
MAPK14 NFATC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15649893 20516082 16648474 12944472 11997522 10788511 15304486 10747897 17255949 10652349 11274345 12697810
MAPK14 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15649893 14580335 16648474 15371334 17072322 10747897 17255949 11274345 12697810
MAPK3 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
MAP3K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 25241761 15315965 12049732 24135036
PPP2CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 18588945
MAPK13 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
PRKCZ MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
MAPK3 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 16009338 12213825 8384717 10995751 12048245 15878863 19327116 19443782 15212693 15367685
MAPK3 SREBF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10627507 14988395
MAPK3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 32205409 20150555 21983342 11904305 14593115 18199680 8226933 14744793 16079281 19318349 20882567 22266860 28574228 21097497 8388392 32615164 16377629 19245816 18775330 9604935 15212693
MAPK3 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17081983 16156666 19413330 11027280 9620846 33676893 23331499 8226933 20068231 18988627 12193595 18491316 18691976 8388392 19651622 10197981 18775330 19115199 9604935 15212693
MAPK3 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 18448488 19413330 11335711 9343414 23331499 15465816 25584415 12576423 11350938 20068231 12681450 10417333 12763138 9872331 18988627 11780390 18491316 18669648 11404481 10521505 18691976 19723038 20058876 14551213 10446219
MAPK3 SREBF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10627507 10915800 18669648
MAPK3 PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12529413 10655479 10628747
MAPK3 NFATC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10652349
MAPK3 NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17804409
HDAC3 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC3 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
AKT1 MDM2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11154281 11715018 11923280 15169778 17680028 20214616 20398329
HDAC3 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
MYCN MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15917661 15644444 15927364 19649205
TP73 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20921405 15734740 20156675 10469568 11245471 10207051
PIM1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19166854 18467333
USP7 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 17936559 26460617 15916963 24462112 22056774 18566590 20816748 16402859 20713061 16943424 17380154 29236775 16082221 26238070 34799561 16845383 16474402 28406480 27452404 28196907
AKT1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 11756412 11923280 20856200 20452955 20398329 18332867 19664995 10217147 11154281 19216069 20214616 11463845 19166854 15527798 9829964 17570479 16680151 17646672 12145204 15169778 15140942 25241761 11715018 25209720 17680028 21930127 11504915 29311840 15574337 23397142
MDM2 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 18499675 17700533 26025930 25417702 19218448 21088494 10321734 10469568 10435614 20588255 25301064 10207051 11223036 21261729
MDM2 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15195100 12759344 14507915 16713569 12915590
SP1 MKI67 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21611785 22890831 22125028 20963645
MSX1 TBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10215616 16713569 8700832
PCNA PARP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA PARP1 â—¼   SHARES_COMPLEX 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
SP1 PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9428683 9493965 17003407 17961220 11278663 12657578 15777284
CASP7 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9875225 1558065 16374543 11058599 9463409 11170436
PIK3CA PIK3R1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
VEGFA PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
STAT3 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733515 24218138 23963458 15793565 16293640
CTNNB1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10477752 25241761 16219695 11716761
SYK PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16921024 15536084
PIK3R1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10527852 16799564 19442713
CSNK2A1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17145710 16873060 19380586
RNF4 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23028697 18708055 15707587 24907272 18408734 21252943 22388745 24637324 19380586
PRKDC MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11749722 16319174
PRKDC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 318.0 1.0 Omnipath 27120806 14555685 20028775 20176926 11287317 27542271 26740621 11731414 12393602 34197700 17993646 21940452 21946537 11278872 22975685 16908595 18316359 34073781 24735537 18039660 24652283 20856200 26170313 21300025 15388791 19144640 26297026 17545609 33941854 16280327 10625301 33845796 25918246 34385295 17537996 14645219 20804212 15084259 12169689 21795477 22071574 23913047 34021259 21695150 15684384 33958720 14530366 16670089 19487463 19223464 17303569 25481872 15475446 17116771 28967905 33753495 12438236 29562639 16753042 33836561 19073147 15169778 16891474 19477925 16338973 16397245 34562454 15821749 33767437 34087103 11409731 18381446 15737995 27481935 11313365 26700621 17210635 25447541 33931486 17827393 17126298 15262962 28542588 33574930 11821945 20471940 15461589 17077177 33579227 26921343 17386266 33744230 26848618 12944390 33566837 26902421 21042280 21763421 34380642 18321849 14593122 25775124 25739674 17229808 26351843 24102046 23757022 33532186 16043647 24632620 12781924 25738875 10864894 17974989 25719244 15806160 16497987 25851605 20501647 18439899 28209968 10973320 24819169 25745998 34383763 19592491 19244117 19204084 29088759 26871475 34257082 26755732 17237292 17709744 17640984 34405859 18480058 33995548 22310280 20211239 12052823 22580611 31937616 19920202 26745759 15905173 12499277 15028555 27162341 21106850 33562475 30065170 23462102 15678105 15642728 27065332 28558072 28977846 15319269 21339742 15855334 21045808 20145118 21297104 18632646 17379600 15471950 23474758 26887938 11375271 20013032 18701889 16540596 15314172 28515473 15964826 19638206 25892239 28692056 20530876 27505672 25100728 21242970 17297446 10542266 14670178 15548374 33741342 12429574 11002428 15831486 17116756 25435370 32833881 11402048 25361894 15207915 20729916 15625077 18677106 12869565 11250155 21356307 15967841 31936857 25943101 18394555 12644590 14500543 18691549 27197158 15623569 33477794 12062056 16754797 15383526 21909137 21949775 20085797 16807298 15899889 33868961 23940660 23434580 33927349 23899556 14990993 12000752 27880719 26065416 19060924 34520759 14679308 15334055 17283158 25257795 17548608 30586628 24437487 20124472 15289327 23325788 21208159 33664452 31679687 12791703 15047712 17166829 26146988 17329400 20660158 21532621 21806543 20179209 25661488 20957047 17562705 19915805 12606948 17277771 10377409 25893295 17270736 16407838 20597130 15047168 28658616 16357520 15537647 12818176 11425855 17210830 19800394 12506011 21310961 16963136 21996732 15695828 33835469 11701613 19010331 26686089 28915558 15467762 17586693 18456663 34381564 18765673 20233713 34208786 11029403 22084251 20622007 12077256 11313948 16917505 19448664 27391337 15792956 21172654 15608670 12438239 19875458 22014578 25071014 11809760 18728186 31391321 33891611 19805619 33407730 25868858 25320242 34348155 20832730
PRKDC SRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17570479 8407951
PCNA RFC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8999859 12400013 15225546 19285992 10353443 12192049 9649448 26496610 12045192 12171929 24958773 8861969 9092549
AKT1 SMARCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17570479 16568092
STAT3 IL1B â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
STAT3 VEGFA â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
STAT3 CEBPB â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
STAT3 PIM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10068671 18426800 17717068 22273698
STAT3 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 22076197 19880237 12824281 20232316 18320073 20482858 17557905 21354136 19020709 17937859 20880395 25101566 16007214 19284568 19336759 20236940 10744750 11960372 15688401 19082717 21344490 20939432 17533737 21733558 18021292 20720018 11744720 23104276 16540670 11960378 20043094 21278793 21418908 15665043 15735682 21172343 23756865 20052595 17169602 18184402 21731766 23911788 12545153 22313388 16899623 20709526 18408167
STAT3 SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15240880 19233843 16226915 19913854 15913829
STAT3 CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10867011 17471507 24011072 15389878 15486993 9163525 25787076 15930175 9528783 16293640
SYK STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10777558 25416956 21516116 20133729 31515488 16189514 10825200 32296183
MAPK8 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 23255093 17502367 21702955 19413330 11335711 9343414 23331499 15465816 12576423 11350938 20068231 12763138 9872331 18491316 18669648 10521505 18691976 20058876 15979846 14551213 10446219
MAPK9 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20871632 18691976
MAP3K1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17563747 11278353
CEBPB STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11134330 18266962
STAT3 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15870198 16861352 25854163
STAT3 VEGFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17987801 16716598 13130303 7768934 11528470 9278421
SMAD7 STRAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 17314099 10757800
SP1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 24074563 19843528 19047367 15951564 10778946 21536653 19287963 12019268 11452025 19360348 18365874 14577922 19318640 14611815 12368233 15226182 15656906 21553143 15067344 21132266 11342218 16452190 21590772 19649288 17141225 12151407 16234237 17325661 18093727 19106100 18754863 1236823 10637317 21693539 22554713 19912441 11279234
TP73 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15734740 22496369 16234237 16205639
ESR2 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12122114 10805720
AKT1 TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 25999477 22366458 10224060 17570479 22902867 15843522 18775701
CREM TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22586041 17579082 9545284 20018859
SP1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 23733894 12759366 27030318 22534375 7649977 12509451 12378384 15175554 18357389 10829018 11390427 17897957 18218727 8258705 12560487 17047073 21320120 7918637 16847329 10559188 18930140 20068037 1618817 21784970 10688670 10913190 17307735 18467438 21411747 11500175 20221720 20701940
NFATC1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10688670 11911478 12560487 18097033
DNMT1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21765477 24875904 23335796 22742857
NFKB1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17513725 12058956 24337575 12657243 17704137 12471036 17707233 7624137 11259437 12686724 16433741 26114754 20237317 7876168 16707469 12117498 14976218 10485496 15465827 8622636 15812247 21138578 18990758 10748079 15013838 15749903 16916598 17646159 10754326 16040075 10837498 18285351 11675405 11739517 15743782 20066113 20617556 17085785 8530146 8805669 10919279 14960579 1740105 10963848 16055086 9742085 17292554 10553096 11312646 15543947 17442180 16285952 10079106 11297551 10551799 10201927 12907458 8679226 9281604 22782967 8219230 11749970 9916895 11094063 11490006 7895918 1618817 16483936 18057724 20722069 16569682 9452482 17407192 17082635
CEBPB TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 10775602 21059644 9831247 26114754 19530226 20220144 9566900 10748079 19489038 8726660 10754326 19109189 10838190 14514692 24012417 12184911 23971673 23590297 14976147 16850160 10629048 22074460 15850785 7929820 10887174
CEBPD TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10796884 15284209 10629048 22514649 20220144
TNF NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19053972 24083678 25215581 29088783 24386331 25888769 20460401 16866128 19934328 9363938 24349153
TP73 CDC25C â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19861536 11396965
PCNA DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17991895 18384127 31235252 28073635 12354094 9302295
SP1 CDKN2C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18642058 15107822 22504641 12077144
CDKN2C CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 25910212 21988832 11900540 23455922 17353931 26186194 27107012 23602568 25416956 8891723 31515488 32296183 16915296 8001816
PIN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16713569 11533658
SP1 NFYB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18654640 9748295 9604010 18559965
NFYB SREBF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 12177166 18559965 9748295 18654640 8798690 20450493
NFYB SREBF2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 12177166 18559965 9748295 18654640 8798690 20450493
MYOD1 MYOG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 21543328 16901893 18676376 12782625 17940050 1581290 12578986 12694204 15870273 1718977 17562853 21892963 22773876 15149596 16858404 20026657 10548518 20466877 11279181 24550007 22710712 17932502 2560751 7852366 11784084 19723804 8119948 15798192 16847330 12101422
HNF4A APOA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8369280 1639815 9880489
SP1 CA9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11672442 11429308 16270297 15184875 12615703
PSIP1 BANF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 9860958 9038339 3032450 16175173 9188609 16291214
SP1 ITGB5 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10964912 11007770 11013220 15001984 17705132 18353785 21252118 23338822
SRF MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17377068 8744946 9658178 23406902
MYOD1 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10082523 1662816 9148896
CDK4 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21902831 10022835 10601020
MEF2C MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15743821 9418854
NFKB1 NFKBIA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 1829648 21725609 23178297 23572150 8096091
NFKB1 NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17876798 15499023 17709515 7775482 11744993 10454561 11060311 12885753 9250151
NFKB1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 61.0 1.0 Omnipath 17145710 25609649 7862124 1340770 16210649 16970925 21719482 9738011 9865693 10497169 8657102 9572494 9315679 21988832 8887676 10329681 1829648 14743216 17003112 11313474 20558726 26496610 7867065 7891711 10837071 7831327 15836773 26186194 11571291 15214841 17561400 16846590 9566883 8096091 15371334 7479976 11020244 9426183 16493424 15145317 8631829 20237821 20980497 16513645 9597130 7479848 7739549 7628694 10655476
BTRC NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 46.0 1.0 Omnipath 11850407 27001857 20638939 10075690 25190485 10497169 25900982 9859996 10338206 24912152 20797629 22590978 10437795 20353940 9990853 20558726 16189514 12482991 19053519 10713156 22022389 10066435 22388891 24464578 9990852 10072378 11027288 10644755 20851351 19933270 17319651 11158290
HSPB1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 12897149 9047237 16439988 19324872 18266962 14761954 9169414 10694513 19011223
SYK NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21674813 21459462 19014652 12711606 24101387
CSNK2A1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 10783893 16007147 9721103 11673497 12138192 10723127 7796813 8657113 8622692 10421793 12167702 12403772 8668171 8657102 10398585 8601309 9214631
VEGFA SYK â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
VEGFA SYK â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
VEGFA SYK â—¼   ENZYMATIC_REACTION ✅ 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
LMO2 VEGFA â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 10048576 11528470 13130303 16556862 16716598 19208835 19839049 20589835 20731704 21081489 21224848 22349261 22439866 225147423 7768934 9278421 9811054
TFAP2A VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11191053 16790435 11731421 9049304 12570801 14744778 8466753 11007955 23506169
NFKB1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18184402 17673602 16684540 15517885 12160329 15856023 18056465 20538607 17407600 20103608
VHL VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 12539169 8625303 9572397 9370235 10581162 19801654 12912922 10189987 9689663 7533661 10804089 8855222
PGR VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9458078 14662796 12568850 15860260 22542550
SP1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 19671799 12509426 12560084 16638750 15342781 10910082 19147754 22992725 15217947 15737464 11904305 12429844 15688401 15544046 12615726 11678207 15188178 18021292 15883203 15477724 18454179 23652833 16239639 23369005 8910439 15026340 11007955 12644537 14597566 18575762 11232768 11731421 12482909 12570801 15582599 16540671 16790435 18632621 9264407 10581162 16788159 11040101 21115498 23765166 11060301 22326662 23506169 15613498 15970595 11191053 10816575 12975317 20435036 16949073 11980848 14647449 15302997 9271438 15039660 16982770 11559575
EPAS1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15156561 15192019 19010893 15191799 19080330 20061373 9113979 16900513 20574527 10531360 21057546 21145972 11350893 16778202 23213445 11301389 20807755 9746763 9665461 11751212 12750296 24062466 11912213 16920734 17322369
SMAD2 SMAD7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   PROTEIN_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15183844 10887185 10753944 10843994 10559222
CTNNB1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 15684397 21071413 18988627
SMAD7 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 17438144 21071413 9892009 9892110
NCOR1 SMAD2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
SMAD2 SP1 â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020
SMAD2 SP1 â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020
SMAD2 ITGA11 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9389648 9670020
SMAD2 NOS2 â—¼   DOWN_REGULATES ✅ - 24.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 21042762 21614932 22331441 23390297 6357187 8871614 9389648 9670020
SMAD2 TBX21 â—¼   DOWN_REGULATES ✅ - 24.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 21042762 21614932 22331441 23390297 6357187 8871614 9389648 9670020
SMAD2 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19558215 10878024 12631740 11013220 11114293
SMAD2 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11160896
HDAC3 NCOR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 NCOR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 NOS2 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 11509652 11013263 16195251 11931768 16469706 21258344 17694085 10860984 16917504 10944117 23752268 16713569 14527417 11466315 11804585 12628926 15601853
CSNK2A1 HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17081983 15805470 26663086 27798112 18452278 26356530
NCOR1 NOS2 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NDUFV2 NDUFV1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFV2 NDUFV1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
MAP3K1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12228228 9405400 25241761 10465784 15757900 15299005 14500727 21152872 26538579
SMO AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20016067 20643644 20956384 21209912 18820483 17641202 17688959 18997815 19549984 19592253 16537363
SP1 TBX21 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10964912 11007770 11013220 15001984 17705132 18353785 21252118 23338822
SP1 ITGA11 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10964912 11007770 11013220 15001984 17705132 18353785 21252118 23338822
SP1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15531587 10684646 23280667 21631282 17108117
SP1 NFYA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18654640 9748295 9604010 18559965
SP1 NFYC â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18654640 9748295 9604010 18559965
SP1 SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19716432 20971080 20179320 24458133 18068676 17449871 15462672 21696544 15330762 22511764
SP1 CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15922873 10196209
SP1 IVL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15191537 16374477 17882273 15025563 9512462 9895295
SP1 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9328340 8923463
SP1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11160217 9339900 19753117
SP1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12554796 12706304 15019994 20087433 10894148
SP1 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19540905 15651981 23307400
SP1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18234965 7565762 10411657 23133566 10860921 9458366 17363581 7621073 8103518 10644769
SP1 DHFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9363748 1834700 8552092 1597451 8622648 9591776 9819401 11389717 11158299 1740417 1820211 12788094 3945313
SP1 NFYA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19564345 12153142 10748033 16442295 23160377 12502798 10542271 9516473 22154511 12697323
SP1 HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7553870 9060426 2674689 24669866
SP1 ZBTB7A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19444642 23027183 19723341 18368381
SP1 UTRN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11237613 15172107 11997063 10871758
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
SP1 CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17965828 9528783 20506344 17471507
SP1 APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22901716 11278817 10829013 15164326 15375792 11121483 23293065
SP1 PPP2CA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19750005 19420015 12076969 21420382
SP1 MAT2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11124935 11476892 11427482
SP1 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14567977 22815527 21123453 14645238
MAPK8 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 28831131 22266860 18199680 19245816 25398907 17570479
CSNK2A1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9153193
HSPB1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19656944
NFYA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10393239 12427542 10446910
PRKCZ SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23148884 16943418 18258854 19464346 27320013 17049555 20953893
SP1 SREBF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16713569 18068676 10224053
SP1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15737644 15710382
NFKB1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 8413223 17707233 11058167 12686724 16433741 18285351 8021507 9878621 14960579 10963848 9058643 15543947 20696864 8679226 11035101 15972680 20336759 18772363 10080875 17082635
CEBPB IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 21917825 12072435 9372929 16867259 20702408 17283046 10464291 16569740 10801783 15812237 22260630 10841183 10838190 10383163 9376596 17386941 10956548 12759449 11278846 12468538 11035101 11801594 2112087 12355443 15383601 16439360 19806478 22074460 16399630
PRKCZ AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 11585925 15884057 14560023 16189514 11748077 18353613 11723139 10085094
CSNK2A1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 29732088 17374729 21506126 11689703 10671551 12149249 15818404 10747897 10837139 20976471 19662498 21285348 11035045 11707428 21735093 17444818 20558317 11972058 16707567
PIK3CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25793261 19117013 21041639 24950409 21816939
PPP2CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 21159657 26256536 15743829 10026142 20452955 11438723 18559511 11839802 19996169 19216069 16406523 10995457 18042541 19556239 18588945 16680151 11087733 18160256 15367694 18039929 18077353 11812651 16044149 20360384 12637511
PPP1CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20186153 14633703
AKT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20858269 23331499 20028971 11882383 21303971 17680028 20214616 22094462 17287208 17374729 20398329 21506126 21402455 12040186 19623618 12063252 18218901
AKT1 HSPB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12740362 11042204 19593530 22983196 17510053 23397142
AKT1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 26553800 24492612 27521372 26216216 25949795 21151116 21565170
HDAC4 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 12709441 15743821 11279209 15964851 10523670 23752268 11792813 11504882 18332106 10737771
CSNK2A1 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8663403
NFKB1 NOS2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 21725609 23178297 23572150 7500013 7508926 9486205
NFKB1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10085153 11438703 17720813 16318585 9754583 16283237 18057724 9685183 17081374 12595462 15350552 19766095 23646894 24360823 11036073 15170030 22949549
BTRC NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12482991 10835356 11158290 11953428
NFKB1 NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9486205 7500013 19383900 7508926
CCND2 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 25910212 17517622 27107012 11896535 10477583 9325318 31515488 16189514 32296183
PRKCZ MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10962008 8702918 18667433 17646398
CEBPD CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7646815 18703634 7910803 11559710 18092000 1741402
CEBPB ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9040943 15044620 7961962 9712708
PPP1CA CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9543386 14592972 11897663 16467385
MAPK9 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12742231 20220133 16964243 8119945
MAPK8 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12742231 20220133 8119945 7513216
CSNK2A1 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15064744
CTNNB1 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
CREM CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 7760825 15752744 9280058 15024072
CSNK2A1 HSPH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 10772927 12558502
CSNK2A1 MAPK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11062067
CSNK2A1 NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16904112 18250151 25825525
CSNK2A1 SRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 1547771 19778940 1740119 2046671 92191991 18669648
CSNK2A1 TFAP2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21777522
CSNK2A1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12700239 12432063
CSNK2A1 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8384219 17368182 8622969
BTRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 23514615 17053147 22912335 17145710 27001857 20531388 18851830 12820959 24451375 18805092 25900982 11818547 16798748 19061640 19956254 23331499 24912152 19150432 22017875 24501426 28018973 16376880 21466614 27316454 19053519 26506240 14516475 25149538 10023660 22682247 10228155 9461217 24464578 18354482 26091241 10074433 12114015 9990852 14706645 18650423 25873176 19966869 25515538 20851351 22730322 24469040
MAPK9 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 19623618 18423204 25639486 22074626 19667122 18604449
KMT2A HOXA7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18082152 15941828
TBP HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8648740 9199313 16330756 8218418
NR1H3 SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 18854425 19366697 16831124 19933273 24277692 18202130 20868688 16112614 26120082 15855229 12730331 24265317 21094755 22511764 19716432 21266776 11287605 11694526 18420801 22984430 18684130 24458133 21540177 21979752 19258656 15330762
MAPK10 NFATC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16648474 10978313 10652349 11274345
HNF4A APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7838720 9003181 7961760 8464705 22282358 8626539 9357782 7615825
HNF4A APOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11244563 11229886 9921275 15933209 10859308 8344962 1639815
HNF4A APOA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8626539 8464705
ESR2 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16361351 11799247 18753331 11583108
ESR2 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16293641 12761896 11014241 19001520 9717846
NFYA SREBF2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 12177166 18559965 9748295 18654640 8798690 20450493
NFYA SREBF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 12177166 18559965 9748295 18654640 8798690 20450493
NFYA ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18234965 22154511 9187262 16223781 7961962
HMGA1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10085153 18279675 11056164 14630716 18937643
PSIP1 HMGA1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 9860958 9038339 3032450 16175173 9188609 16291214
SREBF2 NFYC â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 12177166 18559965 9748295 18654640 8798690 20450493
SREBF1 NFYC â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 12177166 18559965 9748295 18654640 8798690 20450493
SREBF2 PON1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20728021
SREBF1 SREBF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14702347 16282353 9786926 11278785