ABL1
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
CAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20808760
1000457
|
ABL1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
MAP2K1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15994315
15121878
|
CASP3
|
BID
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
CASP9
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
CASP3
|
CASP9
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12011067
15573119
|
CASP3
|
AKT2
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
17544405
5219985
|
HDAC3
|
CCND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16461912
0506281103
|
ATF4
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18729081
20101207
|
EZH2
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20132185
21697275
|
MAPK3
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24530506
|
ITGB2
|
KEAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
MAPK3
|
IRS2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7739560
8816480
|
MAPK3
|
GATA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22227582
11585926
|
MEF2D
|
MYH10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15728583
|
MEF2C
|
MYH10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15728583
|
ROCK1
|
MYH10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15774750
|
GATA4
|
MYH7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10998641
10212267
|
NFATC4
|
YWHAQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10611249
8005424
|
FYN
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ATP1A1
|
EZH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
ATF4
|
DISC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12812986
|
MEF2C
|
DES
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8062833
8626009
|
MEF2D
|
DES
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25653159
|
KIF5B
|
YWHAQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
ADRA2A
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31160049
1849000
|
GNAI3
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8327893
19703466
|
ACTG1
|
MYH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9885284
11854399
|
ITGB3
|
ITGAV
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214491
11546839
|
PPP1R12A
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL2
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
FYN
|
CD28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8946678
9973466
|
FYN
|
CACNA1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
FYN
|
CD80
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8946678
9973466
|
GNAS
|
ADCY4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9228084
21406690
|
HDAC3
|
BCL11B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219549
17245431
|
HIF1A
|
ITGB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19828020
23640055
|
ESR2
|
CAV1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12138116
16423895
|
GATA4
|
MEF2C
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15843409
15253934
|
MEF2C
|
MYH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15728583
|
KIF2A
|
KIF2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7822426
17538014
|
CAMK2A
|
ACTA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HLA-DRA
|
HLA-DQA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
DCTN2
|
CAPZA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15473859
15738427
|
KIF5C
|
SNAPIN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
YWHAQ
|
MEF2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214226
11433030
|
MEF2D
|
MYH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15728583
|
CAMK2A
|
ATP1A3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NR2C2
|
ESR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
11844790
|
DYNC1LI2
|
DYNC1LI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18535146
10491388
|
DYNC1LI2
|
DYNC1I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18535146
10491388
|
CAMK2D
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20668654
1000426
|
GATA4
|
AGTR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9207128
10579051
|
SRF
|
GATA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11003651
11158291
|
THRA
|
MED17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14576168
5216777
|
YWHAQ
|
KLC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
BDKRB2
|
AGTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
AGTR1
|
YWHAQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
ACTG1
|
MYBPC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
DCTN6
|
DYNC1I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
815.0
|
0.81
|
STRING
|
36370105
|
ACTR1A
|
DYNC1I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
EP300
|
ATF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
10327051
24069158
|
ROCK2
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30413785
33742100
|
SYT3
|
MYH7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
COX6C
|
COX7C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31536960
33961781
|
EZH2
|
HDAC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23079660
21685935
|
COX6C
|
COX5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31536960
23260140
|
HIF1A
|
MYH4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
HIF1A
|
MYH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ROCK2
|
ROCK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
MEF2B
|
MEF2C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ESR2
|
PSMD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29509190
25604459
|
MEF2B
|
MEF2D
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CAPZB
|
DCTN6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26344197
|
DCTN4
|
DCTN5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26344197
|
SYT3
|
MYH4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
EDNRB
|
EDN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16713569
12972292
23597562
|
KIF2B
|
KLC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
DCTN2
|
DYNC1LI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
827.0
|
0.82
|
STRING
|
36370105
|
ESR2
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11500849
18765668
|
SIX1
|
MYH7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
ROGDI
|
MYH7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
ATF4
|
DISC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31413325
12812986
|
AGTR1
|
CAV1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DCTN2
|
DISC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
90000000
31413325
17043677
|
KIF3C
|
DISC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
90000000
31413325
17043677
|
ROGDI
|
DISC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
90000000
31413325
17043677
|
MED17
|
MED24
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
22939629
33961781
26344197
24981860
|
AURKC
|
MYH4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
SIX1
|
MYH4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
MED12L
|
MED13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
CCND1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
HLA-DRB1
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
5220278
7477400
|
KIF5C
|
KLC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
33961781
11319135
|
EDN1
|
EDNRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16189514
10770212
16713569
7509919
23597562
|
CASP9
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11242052
8900201
25241761
1067155
15941357
11230124
15507451
18723680
17437405
|
MEF2D
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11096067
10825153
10933397
|
MEF2C
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
21556048
9001254
|
EP300
|
SMAD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
10205054
20851880
22365546
16613856
10673036
|
EIF4G2
|
EIF4G3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
DCTN2
|
DYNC1I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
COX6C
|
COX7C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
856.0
|
0.85
|
STRING
|
36370105
|
ATF4
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
14630807
17872950
10350644
12471036
16219772
|
CAV1
|
INSR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10598578
31217420
|
EIF4G1
|
EIF4G3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
ADORA1
|
GNAI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
COX4I1
|
COX6A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
CASP3
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10364179
11399776
18723680
|
GATA4
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
18252717
27208796
11481322
|
NR2C2
|
HDAC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12943985
21670149
|
HDAC3
|
HIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17273746
11641274
|
MED13
|
MED17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
MED17
|
MED13
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
29568061
26344197
24981860
|
MED13
|
MED24
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
24981860
22939629
29568061
26344197
|
DCTN2
|
DCTN6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
27173435
26186194
|
DCTN2
|
CAPZB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
27173435
26344197
|
DCTN4
|
CAPZB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
28718761
26344197
|
DCTN4
|
DCTN6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
26344197
|
CASP3
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
MED13
|
MED24
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
DYNC1LI2
|
DYNLT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
BAD
|
YWHAQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
DYNC1LI1
|
DYNLT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
CAMK2D
|
CAMK2G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
EP300
|
CCND1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15951563
10567390
11788592
|
ESR2
|
MED24
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
29509190
21182203
11867769
|
GATA4
|
SRF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11158291
11003651
|
KLC3
|
KLC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
26496610
|
KLC3
|
KLC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
26496610
|
COX4I1
|
COX7C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
GNAI2
|
GNAI3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
COX6A1
|
COX7C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
MED17
|
MED24
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
ABL1
|
ABL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15735735
12569093
27229929
|
HDAC3
|
CCND1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15713663
12048199
16461912
20484017
15558026
|
INSR
|
IRS2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
8662806
8626379
9195949
|
DCTN2
|
DCTN5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
27173435
26186194
26344197
|
ESR2
|
MED17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
29509190
21182203
11867769
|
MAPK3
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19777442
10597268
12566304
|
HIF1A
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15240700
12402042
15024076
|
EP300
|
KAT2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
23667505
23555303
21559432
|
EP300
|
MEF2C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11796223
11062529
9001254
|
EP300
|
MEF2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10825153
11796223
11096067
|
MAPK3
|
MAP2K2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10567369
19219045
8013650
|
MAPK3
|
MAP2K1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10567369
19219045
8013650
|
HIF1A
|
ITGB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20517715
15235127
|
GNAS
|
ADCY9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9228084
21406690
32196115
|
CD28
|
CD80
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
2164219
7964482
21982860
1847722
7545666
|
TEAD4
|
HIF1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19236848
24213609
21540178
|
HIF1A
|
EDNRB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19783678
18411415
|
HLA-DRA
|
HLA-DQA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
DCTN4
|
DCTN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
22863883
33961781
27173435
26186194
28718761
26344197
|
ESR2
|
MEF2D
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
ESR2
|
ADORA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19376833
|
ATP1B1
|
EZH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
ESR2
|
DNAH9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
DYNC1I2
|
DYNC1LI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
KIF5B
|
KLC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
908.0
|
0.9
|
STRING
|
36370105
|
KIF5B
|
KLC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
MAP2K2
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
DYNC1I2
|
DYNLT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
KIF3C
|
KIFAP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
KIAA0368
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
GNAI2
|
GNAI3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
22939629
33961781
26186194
|
DCTN6
|
DCTN5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
33961781
26344197
|
ADCY9
|
GNAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
CNGA1
|
CNGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
CACNA2D1
|
CACNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
CACNA2D1
|
CACNG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
CACNA2D1
|
CACNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
COX5A
|
COX6A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
CAPZB
|
DCTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
KLC2
|
KIF5C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
9624122
26344197
|
KLC4
|
KLC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
22863883
30217970
26496610
|
COX6A1
|
COX6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
ACTR1A
|
CAPZB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
CACNA1C
|
CACNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
ACTR1A
|
DCTN5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
CAMK2A
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
HIF1A
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
17382325
5219810
|
CAPZB
|
DCTN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
CAMK2B
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
HLA-DRA
|
HLA-DRB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
MAP2K1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
HLA-DMB
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
KIF3B
|
KIFAP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
HIF1A
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
15280364
19589782
16543236
11823643
22807441
19666581
16189267
18047470
15342390
12042299
19680224
22735262
23448368
26135796
23618863
14691445
19696166
11959990
27320910
16847340
24821806
22789427
17906695
8917528
20620956
20000859
15261140
16081065
12778114
22219185
15154850
25192544
22075993
19071119
22908229
19940151
21187066
24421387
23880760
11940656
23966271
26826385
26944191
12588875
23746844
11063749
27808477
19074848
20603618
15155277
18268343
20829524
21148070
12914934
17502379
22684029
17382325
26751287
|
CAMK2A
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
DCTN4
|
DCTN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
ACTR1A
|
DCTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
COX4I1
|
COX6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
CAPZB
|
DCTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
ATP1A1
|
ATP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
DCTN5
|
DCTN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
ACTR1A
|
DCTN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
DYNC1I2
|
DYNC1LI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
DCTN4
|
DCTN5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
DCTN2
|
DCTN5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
COX4I1
|
COX5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
HLA-DRA
|
HLA-DRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
DCTN2
|
DCTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
DCTN2
|
DCTN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
ACTR1A
|
DCTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
EP300
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
HLA-C
|
ABL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11513144
12515815
12917349
16606694
18835194
9751747
|
HLA-E
|
ABL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
10358164
11015446
11062502
12731048
15120186
15536084
22464172
2731048
8478617
9485206
9486650
9655483
|
FYN
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12522270
16787943
17570479
16912036
16076903
17474147
11847100
|
ABL1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
22553782
24974292
29066624
15657060
20841568
28177918
|
ABL1
|
CAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
18083107
17389395
11094059
19534553
8632005
12531427
27292265
24632723
11075810
12036959
15592455
20841568
15951569
20808760
16151024
|
ABL1
|
ABL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12569093
15735735
20841568
|
ATF2
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9990041
10915780
11850817
11410592
11739785
15691880
16405968
10464245
10500157
15314161
10066798
|
MAPK13
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
15187187
19436832
9207191
10581204
15140942
20506250
21614932
19135240
16393692
12244047
11274345
|
MAPK3
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10777545
12110590
20068231
15304344
15192015
19647037
|
YWHAQ
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
21988832
15694340
11697890
8929531
16713569
9369453
15280438
|
AKT2
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
15452053
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
12954615
22094462
10949026
11438654
17680028
10516287
18218901
17270021
|
HIF1A
|
BID
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
66.0
|
1.0
|
ACSN
|
10102273
10428030
10428780
10435632
10804084
10823814
11557773
11559532
11744734
11756417
11884613
12402042
12676992
12743597
14672622
14684737
14699081
14762718
15024076
15059920
15199147
15240700
15312748
15369676
15379897
15545625
16110315
16126909
16127144
16517405
16517406
16585195
16782875
16888645
17143338
17418790
17533374
17785433
18054315
18056423
18158893
18718909
19211554
20028863
20427344
20535745
20855962
21051947
21765015
22006996
22841746
22850421
22988108
24006507
25043024
25103413
25732824
7493931
7500013
7508926
8089148
8702901
8955077
9486205
9525945
9707622
|
CASP3
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9727492
10364179
10805722
11832478
11085742
11085743
|
CASP9
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
10708865
9390557
10508159
11230124
18723680
15657060
16977332
15507451
1067155
9708736
25241761
8900201
11242052
9765224
17437405
19788417
9812896
12620238
15941357
12181739
19465923
12792650
15725726
|
CASP3
|
EIF4G2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
10672017
11175261
10371215
10611228
|
CASP3
|
SPTAN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
8940132
9624143
9712874
9811849
8910516
|
CASP3
|
EIF4G3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
10611228
10672017
|
CASP3
|
EIF4G1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
10611228
9819442
|
CASP3
|
ROCK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11283607
|
MAP2K2
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
12792650
18669648
|
AKT2
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9812896
15004527
|
MAPK3
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
38.0
|
1.0
|
Omnipath
|
15547943
20080742
29416675
12040186
15173823
12697810
11940578
19081073
19586613
16227978
12738796
16039586
17466630
17255949
18669648
15187187
19016842
19541618
19091303
19565474
17052211
18039929
18775330
10601235
12792650
11431469
|
MAP2K1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
12792650
18669648
|
HIF1A
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23455892
20360945
20179204
15991006
|
ESR2
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15313930
14764652
18607069
23891847
11986316
18223478
14729654
|
EP300
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17306568
17666529
11788592
23343194
21285352
15576399
21151179
22761862
22290435
16039586
19619488
19623618
17143292
|
AKT2
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17964260
16926151
|
EP300
|
SMAD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12419246
14500836
10673036
22298955
|
EP300
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
75.0
|
1.0
|
Omnipath
|
24821806
12573436
17145710
16847340
12588875
19589782
11940656
25192544
11959990
18519678
23448368
22219185
11823643
12042299
15342390
23746844
19071119
19680224
27808477
15154850
19696166
8917528
17906695
18268343
22735262
21148070
15261140
19940151
23880760
22807441
35430356
14691445
12914934
20000859
12778114
26751287
16081065
22789427
16543236
24421387
17382325
17502379
22684029
21187066
19074848
23618863
23966271
20603618
|
KRAS
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
MAPK3
|
MAP2K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11802164
15239952
21779496
11802165
15260967
|
MAP2K2
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
101.0
|
1.0
|
Omnipath
|
19901323
17081983
11704645
9694850
12750173
1411546
19690332
12932319
18799465
16497976
18083107
11134045
8626767
9006895
17389395
19219045
15342917
9447970
16887817
23331499
17569879
7867743
7559390
21071413
19534553
8226933
20068231
8223433
17272394
93330262
15851026
15811950
26987942
18988627
19494114
18669648
19541618
11242034
15466476
18691976
1381507
17906627
11986622
19933846
8376945
11971971
17192257
11136732
11948414
7898932
7687743
9731057
19651622
11730323
16464493
18983981
11251083
11118451
15580310
19369195
18707149
12920017
15951569
15466214
10746662
15212693
|
MAP2K1
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
106.0
|
1.0
|
Omnipath
|
9694850
17081983
11319218
18799465
17389395
9447970
15342917
8226933
15851026
12270934
12644307
11242034
1381507
17906627
9677429
11986622
8376945
7992057
11948414
7687743
9731057
19197339
11704645
7565670
12750173
12932319
8626767
23331499
12048245
7559390
17272394
15811950
26987942
19494114
18669648
18691976
17192257
8388392
7898932
16464493
19369195
12920017
15466214
19690332
11134045
19534553
10995751
7867743
8223433
8248196
10567369
19933846
17563371
1518847
11730323
18983981
16186792
16135787
15951569
19058874
15212693
10748187
9560161
9925641
9733512
18083107
11104681
9006895
17569879
21071413
7731720
1330321
93330262
19541618
15466476
12925710
11971971
11136732
11118451
10746662
|
MAPK13
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
MAPK3
|
GJA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
9535909
19664994
9535905
12637502
15605363
8631994
17570479
|
MAPK3
|
NFATC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15657420
|
MAPK3
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10551817
18519666
24099156
|
MAPK3
|
SMAD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
10197981
9335504
|
PPP1R12A
|
MYH10
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9354661
8662509
11331307
11942626
|
ROCK1
|
DES
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
10574968
12686604
|
HIF1A
|
ITGB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7539918
15235127
1823643
16716598
12829734
9159130
13130303
9746763
12080085
11566883
10403805
8943284
15451019
9278421
16887934
|
ADORA1
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
3805010
6305455
6162091
31160049
|
GNAI3
|
ADCY5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
23109003
15539636
7935349
16460834
11376933
8327893
|
COX5A
|
COX7C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX7C
|
COX4I1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX7C
|
COX6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX7C
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX7C
|
COX4I1
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX7C
|
COX6C
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX7C
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
ITGAV
|
ITGB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
10022831
10545505
10837075
11146654
11335727
11532940
11553709
12000961
14697347
15031725
16919435
18353785
19161977
19339212
19449109
22035837
7512751
7529872
7657702
8636223
8755653
9295024
9763615
|
ITGAV
|
ITGB3
|
â—¼ SHARES_COMPLEX
|
|
|
23.0
|
1.0
|
ACSN
|
10022831
10545505
10837075
11146654
11335727
11532940
11553709
12000961
14697347
15031725
16919435
18353785
19161977
19339212
19449109
22035837
7512751
7529872
7657702
8636223
8755653
9295024
9763615
|
FYN
|
CD28
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10591186
10648627
12218089
12731048
19290918
19909365
20814939
21378271
22683124
22863785
24440149
27192565
9738502
|
FYN
|
CD80
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9822663
15886116
10849438
12670394
|
FYN
|
ITPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
14761954
28598420
18056410
8633244
|
FYN
|
CAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
9252391
29371975
11805080
12925753
21705803
12529448
11075810
15692085
14992595
8632005
10592173
16943184
12921535
16332692
12135605
20228056
15466865
33804982
24632723
33928090
18347068
34321069
|
GNAS
|
ADCY2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9228084
9395396
1719547
9268375
21406690
|
GNAS
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9228084
6935665
210183
17652154
2022671
21406690
32196115
|
GNAS
|
ADCY5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9228084
9748257
9268375
21406690
|
COX6C
|
COX4I1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX4I1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX6C
|
COX4I1
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX4I1
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX4I1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX6C
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX6C
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
CD80
|
CD28
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11964292
12810107
14764699
15197224
17513775
17629517
18585785
20231889
22437870
23390297
25215878
25582338
26405600
7512027
7523569
9359474
|
CD80
|
CD28
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
21530327
7964482
22437870
2164219
1847722
23954143
15610849
7545666
21982860
21487479
|
HIF1A
|
CAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10804084
16110315
16127144
17533374
20427344
20535745
20855962
21051947
21765015
22006996
22850421
22988108
24006507
25043024
25103413
25732824
|
HIF1A
|
EDN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19783678
11352889
18411415
17431122
12023962
11278891
|
HIF1A
|
EDN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7539918
1823643
16716598
12829734
9159130
13130303
9588211
12080085
11566883
10403805
9746763
8943284
15451019
9278421
16887934
|
PPP1R12A
|
ROCK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9354661
8662509
11331307
11942626
|
ROCK1
|
PPP1R12A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
52.0
|
1.0
|
Omnipath
|
11384979
15723050
18767875
19607793
19701943
9354661
10926869
18077418
18669648
10579722
15826939
12220642
26701920
17525332
19997641
12600888
11931630
11719507
15814590
8662509
12563012
12919947
10601309
18212344
12359219
|
INSR
|
CAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9756945
10598578
12036959
17699617
|
INSR
|
IRS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
19901323
7629118
9195949
18083107
23331499
19534553
7537849
17570479
18988627
7675087
11584304
7526222
12101187
8626379
8662806
8626723
|
GNAI2
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
2121366
8327893
19703466
|
GNAI2
|
ADCY5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
23109003
15539636
7935349
16460834
11376933
|
SRF
|
ACTA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12760745
15933209
8423791
15623502
9571041
|
HLA-DRA
|
HLA-DOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
DYNC1LI2
|
DCTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
DYNC1I2
|
DCTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
DCTN2
|
DYNC1LI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
KRAS
|
MAP2K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
DYNC1LI2
|
ACTR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
ACTR1A
|
DYNC1LI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
SRF
|
MEF2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
21057636
7923378
16484497
15880109
29559111
19116276
19193899
9390517
|
YWHAQ
|
MEF2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11433030
23331499
|
CAMK2A
|
SRF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
11859076
12171911
10753652
12684542
8413226
10318869
|
SRF
|
ACTC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15933209
11969255
8887666
17468179
9571041
|
KRAS
|
MAP2K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
DYNC1LI2
|
CAPZB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
CAPZB
|
DYNC1LI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
CAPZB
|
DYNC1I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
DYNC1I2
|
DCTN5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
DYNC1LI2
|
DCTN5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
DCTN5
|
DYNC1LI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
DCTN6
|
DYNC1LI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
DCTN6
|
DYNC1LI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
DYNC1LI2
|
DCTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
DYNC1I2
|
DCTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
DCTN4
|
DYNC1LI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
DYNC1LI2
|
CAPZA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
DYNC1I2
|
CAPZA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
CAPZA3
|
DYNC1LI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
CAMK2D
|
CACNB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20194790
|
GATA4
|
EDN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10788492
19546173
18252717
11739382
11435416
12724418
|
HLA-DQA2
|
HLA-DOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DQA2
|
HLA-DMB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
EDN1
|
EDNRB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
1710450
1719979
8440682
2649896
|
EDN1
|
EDNRB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12972292
16597412
16713569
15629009
8440682
|
EDN1
|
EDNRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
90829707
6479761
9082970
7509919
16597412
16713569
23597562
15629009
8440682
7647976
10770212
|
PPP1R12A
|
ROCK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9354661
8662509
11331307
11942626
|
ROCK2
|
PPP1R12A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
39.0
|
1.0
|
Omnipath
|
17127075
11062269
26664257
15281089
21242007
28971603
10579722
10047526
11331307
11739394
29955616
12220642
26701920
25168281
23825105
19997641
12600888
27251065
15003930
11931630
11719507
27725371
12563012
12919947
21273559
10601309
|