Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MAPK3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24530506
EGF MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17081983 16024629
PRKCB MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8903320 10327068
CAMK2A STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MPO STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STUB1 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKAR1B PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 26687711 32296183
CALM1 CAMK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8340352 20668654
CALM1 ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7755592 10456332
DPYS DNALI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NOS1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17910475
PPP3CB PPP3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 10195903 7593193
PPP3CB PPP3R1 â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 10195903 7593193
MAP3K5 MAP2K7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219344 17110930
KRAS EGF â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
GAPDH CDK5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CDK5 HTR6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 32047117
PRKD1 ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26580203 22357621
CAMK2A GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKACA GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP1 GAPDH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17959595
DLG4 DLG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GNA11 GNB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25675501 15889144
GNA15 GNB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25675501 15889144
PRKAR1A PRKACA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 24855271 1252328
PRKACA MAP1LC3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20713600
GRIN2C DPYS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GNA11 GNA15 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
HSPA1A MAP1LC3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HNRNPA1L2 HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NR0B1 NR5A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 12482977
SNTA1 DMD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221731 9356463
DLX4 CTBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20818429 16326862
FGF6 FGF9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18552176 18757403
ATP5PF ATP5PD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CALM1 DLG4 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CTBP1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21102443 15834423 35016035 16122695
HDAC2 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30737378 26949739
FGF9 FGF20 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NR0B1 NR5A2 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
COX5B COX7A2 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
LMNA FUS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22412018 25192599 25948554
ATP6V0D1 ATP6V1H â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
PRKACA PRKAR2A â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CALM1 NOS1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CALM1 CAMK2A â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
PRKAR1B PRKACA â—¼   PHYSICAL_INTERACTION ✅ - 0.84 0.84 Signor 26687711
CALM1 PPP3CA â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ATP6V0D1 ATP6V1D â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
PPP3R1 PPP3CA â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 7295928 19896943
CACNA1S CALM1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CALM1 CAMK1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PRKACG PRKAR1B â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PRKAR2A PRKAR2B â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PPP3CB PPP3CC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PRKAR1B PRKACB â—¼   PHYSICAL_INTERACTION ✅ - 0.87 0.87 Signor 26687711
FUS EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18509338 30110629 33742100
RHOA ITPR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 12766172
NOS1 SNTA1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ATP6V0C ATP6V0D1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
NR0B1 NR5A1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PRKACA PRKAR2B â—¼   PHOSPHORYLATION ✅ + 0.88 0.88 Signor 15187164
PRKACB PRKAR2B â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HDAC2 CTBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17967884 31041561 16713569 28947780 16036112 10766745 18212045 11022042
PRKACG PRKAR1A â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
RHOA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MAPK3 PTPN6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16231973 12459785 23109003
CALM1 CAMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7559563 12475216 20668654
CALM1 NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7685187 7493936 1722402
NR5A1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8825555 12697703 12697699
NR5A1 NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23471216 23340581 23537609
NOS1 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19737086 19047631
EGF RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
RHOA DLG4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9870943 9870942 16202622
CDK5 CORO1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26823173
GOT2 GAPDH â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKACA ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17615294
PRKACB PRKAR2A â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
KMT2A ME3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23629655 23399917 19212323
MAP1LC3B DNMT3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NR5A2 CYP11B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11564608
NR5A2 CEL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12853459
LMNA PRKCB â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 22986494 8463284 8034666
SNTA1 NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11747091 12456711 10221915
POU4F2 DDC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11311976 9602135 14741405
PRKACB PRKAR1B â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
HSPA1A STUB1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
DMD SNTA1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
PRKACB PRKAR1A â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
DLG2 DLG4 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 9182804 21653829
CACNA1S CACNB2 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
COX5B PRKAR1B â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
ATP6V0C ATP6V1H â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
DLG4 DLGAP1 â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 18923512
ATP6V0C ATP6V1D â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SNTA1 NOS1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 9412493 10221915 11747091 33961781
PPP3CC PPP3R1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
DLG4 NOS1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 8625413 10488080 9459447
PRKACA PRKAR1A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
DMD SNTA1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 8612778 10747910 18468998 7890602 9412493 8576247 33961781 11571312
PRKACA PRKAR1B â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
DLG4 DLGAP1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
PRKACG PRKAR2B â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ATP6V1D ATP6V1H â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
NDUFA8 NDUFS4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP3CA PPP3R1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PRKACA PRKAR2B â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HSPA4 STUB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
KRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
KRAS CALM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 27410739 12727204 28666118 16043511
CALM1 CAMK2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 3006921 17353931 20668654
HLCS ACACA â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 9630604 14766011 10677481 7732023 16134170 20153287 22123817
NR5A1 CYP11B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14645496 11014212 22079243 12915995 11932209
NR5A1 NR0B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9121493 7677767 16857744 9232190 11990799 16439455 19188450 9658405 10446902
NR0B1 NR5A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 25910212 23331499 14963109 11459805 21071413 19237537 12482977 25416956 11713202 32296183 18988627
PRKACA CACNA1S â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20937870 2844809 1322891
HLA-E PTPN6 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10358164 11015446 11062502 12731048 15120186 15536084 22464172 2731048 8478617 9485206 9486650 9655483
HLA-B PTPN6 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11513144 11994457 8976179 8986721 9605119 9751747
HLA-DPA1 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
NDUFS4 NDUFA8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA8 NDUFV1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFS4 NDUFA8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA8 NDUFV1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFS4 NDUFV1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFS4 NDUFV1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
MAP3K5 MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
MAP3K5 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 12556535 19392652 18855897 17462996 19920149 18641653 23331499 23850759 21071413 12655147 21614932 21133840 12738796 21232017 24378531 15592525 11959862 17110930 26192618 11274345
EGF RHOA â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 12094222 15003992 15175028 15466195 15958574 18423981 19631971 20430953 21098712 8101258
PRKACA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12654918 21572420 20591975 8599934 16109481 34088899 11162591 15890975
PRKCB FLT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
CDK5 SYN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15822905 10880969 26903856 8702879
DLGAP1 DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9286858 9115257 9286856 11060025 22117215 10844022 10527873 9024696
DLG4 NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8922396 9459447 10488080 11052931 11031113 8625413
DLG4 DLGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9286858 9115257 18923512 9286856 11060025 22117215 10844022 10527873 9024696
CAMP PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23109003 15539636 7935349 16460834
PRKAR1A PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 17145710 15655353 17353931 26687711 11834733 24855271 32296183 24700472 9405392 25477193
PRKACA HRH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15107581 15328002
PRKACA SYN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 3118371 12237306 7849051 14557263 10571231
PRKACA PRKAR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27107012 15187164 32296183 17148597 21795691 33608270 25477193
PRKACA ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 2847175 1847804 8132598 19144319 12529267 14741364
PRKACA NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12630910 10400690 1375933 7532810 10874031
PRKACA ACACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 7907095 2900138
PRKACA CACNB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10567342 10441130
CAMP PRKACB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23109003 15539636 7935349 16460834
CAMK2A NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12630910 10400690 1375933 10874031
CAMK2A HRH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15107581 10101032
CAMK2A SYN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 3118371 7890745 9016342 7849051
KRAS PRKG2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 23943869 26590425 9436858 11585916 29311131 20802526 25713064 16483930 24033119 27697864
CAMK4 NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12630910 10400690 1375933 10874031
CAMK1 NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12630910 10400690 1375933 15251453 27885874 10874031
CAMK1 SYN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 3118371 12237306 9395448 8022798 10571231