Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HDAC1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17980157 18319725
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
AR SIN3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 16254079
KLF16 SIN3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11438660 12036432
KLF3 KLF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18687676
HNF4A AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16474850 12466965
SHANK3 PHF12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SIN3B SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
ESR1 SIN3B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16469706 31527615
SAP30 PHF12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11390640 24981860
MORF4L1 SIN3A â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
GATD1 RBBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 20850016 26496610 26841866 33961781 24981860 26186194
MO4L1 RBBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 20332121 17573780 33961781 24981860 26186194
RBBP7 KDM5A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
RBBP7 PHF12 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26496610 26841866 33961781 24981860 26186194
HDAC1 GATD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23752268 20850016 26496610 26841866 33961781
HDAC1 EMSY â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23752268 26496610 26841866 33961781
HDAC1 KDM5A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23752268 33961781 26496610
GATD1 HDAC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26841866 24981860 20850016 26496610
PHF12 HDAC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26841866 24981860 26496610
HDAC2 EMSY â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23752268 24981860 26841866
GATD1 PHF12 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20850016 26496610 26841866 33961781 24981860
MO4L2 PHF12 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 20332121 17573780 26496610 26841866 33961781 24981860
PHF12 KDM5A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26841866 24981860 26496610
PHF12 SIN3B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26841866 33961781 26496610 24981860
PHF12 EMSY â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26841866 24981860 26496610
MO4L1 KDM5A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 17573780 33961781 24981860 26186194
GATD1 KDM5A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20850016 26496610 26841866 33961781 24981860
KDM5A SIN3B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17573780 33961781 26496610 24981860
MO4L1 SIN3B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 20332121 17573780 33961781 24981860 26186194 19553677
GATD1 SIN3B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20850016 26496610 26841866 33961781 24981860
SIN3B EMSY â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26841866 33961781 26496610 24981860
GATD1 MO4L1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 20850016 26496610 26841866 33961781 24981860 26186194 22038470
MO4L1 MO4L2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860 26186194 22038470 19553677
MO4L1 EMSY â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26841866 33961781 24981860 26186194
TLE3 TLE2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
GATD1 EMSY â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20850016 26496610 26841866 33961781 24981860
KDM5A SIN3B â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
MYC SIN3B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24951594 30415952
ESR1 RBBP7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18577416 23403292 21182205 31527615
TLE1 TLE4 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
HDAC1 YY1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
MYC HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 22286234 30415952
RBBP7 SIN3B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 26496610 33961781 24981860 26186194
KLF9 SIN3A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 11438660
GATAD1 MORF4L1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GATAD1 RBBP7 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MORF4L1 MORF4L2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
RBBP7 SAP30 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HDAC2 SIN3B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
E2F1 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10734134 9468140 17980157 26468294 9468139
PHF12 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 23752268 11390640 26496610 26841866 33961781
HDAC2 SAP30 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
NFYC MYC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10446203 11282029
HDAC2 YY1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MO4L2 HDAC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17573780 24981860 20332121 26344197
MO4L1 HDAC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20332121 17573780 24981860 14966270 26344197
HDAC2 SIN3B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15935060 26949739 21258344 24981860 16464847
PHF12 SIN3A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11390640 21440557
KDM5A ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11358960 31527615
GATAD1 KDM5A â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
TLE2 TLE1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 9874198 33961781 24981860
PHF12 RBBP7 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
GATAD1 HDAC1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
E2F1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11564866 18319725 90001421
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
SAP30 RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11283269 28514442 9651585 9790534 10444591 26496610 27705803 33961781 26186194 15451426 11784859
SIN3A RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9651585 17255935 27705803 33961781 24981860 26186194 12453419 15451426 11784859
HDAC1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18634613 11486036 11940654
HNF4A S100A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17101323 19671543 21403839
SIN3A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15695521 28514442 9520398 10640275 14647463 12398767 9150133 10444591 14593184 21258344 12943729 12374985 17956988 11102443 9885572 17962807 26496610 12453419 11171972 16331260 20585571 10220385 25314079 12091390 11931768 17643391 11602581 17827154 12724404 11784859 23752268 18059533 9790534 9804427 26949739 24981860 33961781 19182791 11118440 15451426 12920132 26344197
ESR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17312152 31527615 24051437 33731348 14722073 21182205 15557281 18451880 14506733 15140878
HDAC1 SIN3B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 23752268 11959842 20585571 10357820 15935060 10444591 26496610 33961781 11102443 24951594 26344197
KLF16 SIN3A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12036432 11438660 22203677 35140242
PHF12 MO4L1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22038470 25416956 20332121 21440557 17573780 26496610 26841866 22244764 33961781 24981860 26186194 12391155 19553677
RBBP7 SIN3A â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
HDAC1 SAP30 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
KDM5A MORF4L1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
HDAC2 PHF12 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
RBBP7 SIN3B â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
TLE1 HDAC1 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 19101520 22439931
SAP30 SIN3A â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
LHX4 YY1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
MORF4L1 RBBP7 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
KDM5A PHF12 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
HDAC1 MO4L2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 14506250 17573780 20332121
HDAC1 MORF4L1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
PHF12 SIN3A â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
HDAC2 MORF4L1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
HDAC1 PHF12 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
MO4L1 HDAC1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 17573780 20332121 26344197
SAP30 SIN3B â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 33961781 26496610 10444591 24981860
MORF4L2 PHF12 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
HDAC1 SIN3B â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
HDAC2 RBBP7 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 22939629 20388487 27705803 21258344 33961781 24981860 26186194 15451426 12493763 9885572 26344197
RBBP7 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 19703393 10444591 21258344 11102443 9885572 17255935 10471499 26496610 25885317 22939629 9150135 23752268 9790534 27705803 33961781 26186194 19686092 15451426 12920132 26344197
SAP30 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 11390640 16820529 10444591 21258344 9651585 9885572 15235594 26496610 11283269 18193082 11784859 23752268 16713569 9790534 33961781 12788099 11118440 15451426
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
SIN3A HDAC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16254079 12398767 21258344 12943729 9885572 9150134 12453419 12493763 14749338 22493095 12082111 25314079 12091390 17827154 12724404 23752268 18059533 9804427 26949739 24981860 15451426 26344197
HDAC2 SAP30 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11283269 9651585 16713569 9790534 20388487 16820529 10444591 26496610 21258344 33961781 24981860 15451426 9885572 11784859
SIN3A SAP30 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11283269 11390640 9651585 9790534 16820529 9702189 10444591 21676866 26496610 21258344 33961781 24981860 12453419 11118440 15451426 12724404 11784859
MORF4L1 SIN3B â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
PHF12 SIN3B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
HDAC2 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
MORF4L1 PHF12 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ESR1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22791811 20215421 12697671 10446910
E2F1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21966451 17178887 22508987 21099110 21099103
E2F1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8208548 2721961 7753559 11705881 24038073 8355712 1549358 1567856 12629508
KLF8 MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
MYC NFYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11282029 10446203
HDAC2 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9016636 19139378 11486036 8917507
TLE3 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
TLE2 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
TLE4 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
HDAC2 SIN3A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC2 SIN3A â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
PHF12 SIN3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11390640 21440557
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
AR KLF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19460858 20610535
TLE1 TLE3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10485845 11934263 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
TLE3 TLE5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 11290324 15187083 9783587 11266540 8365415 9887105
TLE3 TLE4 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10485845 11934263 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
TLE4 TLE5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 11290324 15187083 9783587 11266540 8365415 9887105