Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
APBB1 H2AFX â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16818236 19234442
AURKA CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
PIN1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11774038 16713569
RNF8 CHEK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 H2AX â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
RNF8 CHEK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 H2AX â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 RAD50 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
COPS5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18926707
DDX41 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
DHX9 DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
DDX5 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DDX5 TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC DDX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
DDX5 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18829551
GRB2 DHX9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
DHX9 AKAP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DHX9 ZC3H18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DOT1L CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000539 21103407
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20660371 19102934
EP300 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20488183
EP300 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16204234
MYC FBXW7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20638938 19366810
NPM1 FBXW7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18625840 28920929
FXR1 SFPQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 MYH10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 MAD1L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 NONO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR2 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 SFPQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 MYH10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SMARCD1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SMARCC1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 MATR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HNRNPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPP1CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 NONO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 NR5A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 PRKDC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SYNPO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 MYH10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CAMK2D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
HNRNPDL NONO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC HNRNPDL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12695333
MATR3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FUS MATR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27731383
EWSR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8164678 11423975
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
MYC HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20388374 19021144
HDAC3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22002311 18483244
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
MYH10 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PSPC1 NONO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
AURKA NONO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
POLR1H NONO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PLEKHF2 NONO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PIN1 NONO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MAD1L1 NONO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NONO CRTC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0707999105 18077367
NONO STK10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NONO RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NONO GALNT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NONO TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NONO GOLGA8DP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NONO HEATR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NONO AKAP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NONO MYO5C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NONO DHX57 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NONO LIX1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NONO RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NONO TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NONO GJA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19423654 21642354
NONO MIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24349210 23672612
PTBP1 NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218180 16376875
NPM1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219698 17318229
NPM1 IL7R â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SNCA PARK7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0020362 15502874
PARK7 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AR PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 20610535
PRKDC RNF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PRKDC RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PRKDC RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SFPQ PTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15975576 5217783
SFPQ RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SFPQ TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SFPQ TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SMARCA4 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
H2AX SMARCA4 â—¼   COLOCALIZATION 2.0 0.8 intact 7914327 20224553
SMN1 SMARCB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMARCB1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMARCC1 SMARCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1459453 19785031
SMARCC1 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
AR SMARCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15923603 20610535
SMARCC1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15923603 18581278
SMARCC1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 9590696
SMARCD1 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SMARCD1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMARCD1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12917342 16189514
VCP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP1CB RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NCL PPP1CB â—¼   COLOCALIZATION 2.0 0.8 intact 12185196 8262810
PPP1CB IKZF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21750978 19282287
SNRPA PTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PIN1 SOCS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NOS3 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17502619 0611416104
ACTB HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SRC ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 7296071 19903481
ACTB POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10773068 435297
E2F8 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR1 HEXIM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18757415 21423213
MYCN HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
HDAC1 MYCN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
PPP1CA HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17008050
HTT SIN3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
AR SIN3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 16254079
SIN3A KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16254079
HTT BIRC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA BIRC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BIRC5 AURKA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19357306 0900833106
ESR1 HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489 19039095
HES1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19129776
HES1 TLE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19250647 16608701
HES1 TLE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24270405 8687460
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HNRNPA1 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAE RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP1CC RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
USP11 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HDAC6 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CREBBP RELB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12789342
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
CREBBP CRTC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219899 17476304
EWSR1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8552387 12459554
GJA1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11035005 5213074
EWSR1 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21531709 15282325
AR IGFBP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16825320
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
AURKA HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17604723
AR PRKD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 18602367
NR3C1 IRAK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25585690
YWHAE HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10737771 5212359
PPP1CA HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NDN HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HDAC6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TCERG1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
SNCA HTT â—¼   COLOCALIZATION 2.0 0.8 intact 22119730 8292239
MAP1LC3A PRPF40A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
CTNNB1 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32803659 21295277
ESR1 NOS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17921256 0704315104
PRL ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25193864 19524120
AR HNRNPA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535
AR HEY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 15684393
AR PEG10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 17369855
PPP1CA IKZF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21750978 19282287
PPP1CC IKZF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21750978 19282287
NR3C1 OCLN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18501346 18782596
PGR GJA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19423654 22669741
PGR KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9052414
WWP1 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NCBP2 PRPF40A â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CDK1 CDK7 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 20360007 11113184 16327805
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
EP300 PARP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18280497 16204234 19622798 12960163 24636898 33742100
ANDR KAT2B â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10779504 11328859
ESR1 ROA1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 21182205 20348541
FUS SFPQ â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
ARAF DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29777862 25852190
VCAM1 CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
MYC CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
DDX41 SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DDX41 SRRM2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 25920683
SRRM1 DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16159877 26344197
VCAM1 DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
SRRM2 DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16159877 22939629
EGFR DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31980649 28065597
DDX5 U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 26641092
DDX5 DHX9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22365833 26344197
ESR1 DHX9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 21182205 19805454 20348541
AURKA DHX9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23443559 25852190
DHX9 XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15723802 30585729
EGFR LMNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24780295 26320552
EGFR MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
EGFR PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24780295 28065597
EGFR ACTB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22366308 31980649
ACTB EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33742100 21988832
HDAC6 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19344692 15102857 12718889 22778253 23133622
CTBP1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21102443 15834423 35016035 16122695
ERCC6 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16107709 32355176
BMI1 FXR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 FXR2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
VCAM1 GRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
MYC MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MATR3 BTF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 33644029
MATR3 YLPM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27609421 26496610
MYC U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
MYC RAD50 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC XRCC5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC PRKDC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 30415952
MYC PTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
VCAM1 MYH10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
SPB8 NONO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 NONO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
YLPM1 NONO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27609421 21988832
SPA12 NONO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ELAV1 NONO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 19322201
NONO PRSR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NONO TGM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NONO TET2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NONO SRC8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 24981860
NONO GLYG2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NONO SCRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 30833792
NONO SPB7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BMI1 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20668194 34316702
VCAM1 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
PARP1 TOP2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 16794079
H2AX RAD50 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16377563 19234442 31501894 15201865 10959836 18583988
VCAM1 RBM14 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
BMI1 RBM14 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
ELAV1 RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20926688 19322201
ELAV1 SFPQ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 19322201
VCAM1 SFPQ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 TOP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
MED19 UBR5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15175163 31365120
VCAM1 XRCC5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
U2AF2 XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26641092 30585729
VCAM1 XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
CTBP1 H2AX â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34133714 31041561
H2AX HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31504778 28242625
IKZF1 CUL2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MYCN HDAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18003922 31856871
MYCN HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31856871 20697349
IKZF3 HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12015313 30760870
HDAC2 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30737378 26949739
ANDR SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 16469706
BIRC5 MED29 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BIRC5 MED10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DHX57 SRC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BMI1 AKAP9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 NCBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 LMNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26468281 34316702
BMI1 YLPM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 PTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
ESR1 CAND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
ESR1 AURKA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21761334 31527615
ESR1 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
ESR1 DHX57 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
JMJD6 U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
U2AF2 PSPC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26641092 26344197
U2AF2 ROA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26641092
U2AF2 ELAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 26641092
VCAM1 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 PTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 LMNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
LMNA ROA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22412018 25324306
SRRM2 ROA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16159877 22939629
VCAM1 ELAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 ROA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
SRRM2 ZC3H18 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
ESR1 PGR â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
CDK1 BIRC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11861764 17681274
MATR3 DDX5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MATR3 DHX9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
DHX9 XRCC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15723802 14704337 21679440
MATR3 PTBP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MATR3 ELAV1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29395067 29884807
MATR3 RBM14 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MYC NONO â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 17967896 29467282
MYC LMNA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
NUPR1 NONO â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19650074 16478804 32780723
FUS NONO â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 25192599 26344197
RNF8 NONO â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30445466 34017080
NONO U2AF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21566083 26641092 26344197
NUPR1 FUS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19650074 16478804 32780723
RBM14 PARP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11443112 16713569
VCAM1 PRKDC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22623428 33961781 19738201
CTBP1 RBM14 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31041561 30217970
SFPQ U2AF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21566083 22939629 26641092
H2AX XRCC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21679440 18406329 20085707
BMI1 XRCC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20668194 24457600 34316702
H2AX LMNA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20000738 25948554 23658700
ARRB2 SRC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19202075 19122674 11877451 23242524
ELAV1 BMI1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24457600 19322201 34316702
TRAF1 TBK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 25996949
HDAC6 CFTR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31501480 22069321 14675537
ARRB2 SRC8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25241761 17620599
LMNA FUS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22412018 25192599 25948554
CHEK2 TP53BP1 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
CFTR HSPA4 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
H2AFX RNF8 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
PPP1CA RRP1B â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
PARK2 PARK7 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HDAC1 SFPQ â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ACTB SMARCD1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
EP300 XRCC6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15023334 33742100 21988832
MYCN FBXW7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19111882 27837025
MYC ACTB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11839798 29467282
TOP1 NONO â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15848144 24981860
LMNA PARP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 30419336 22412018 25948554 29568061
PRKDC PARP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16794079 9398855 21575865 20085707
ESR1 RRP1B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
XRCC5 TOP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28415827 21679440
WBP4 SNRPA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34133714 16055720
AR SRC â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
SRC TRAF1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10635328 15707590
ESR1 PSPC1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
SRRM1 FUS â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16713569 12581738
TOP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ARRB2 SRC â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
DDX5 ESR1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
POLR2A SMARCB1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
HES1 TLE1 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CREBBP NR3C1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
RNF113A SRRM2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CDK1 SKP2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 26496610 33422522 33961781 26186194 32707033
FUS DHX9 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27460707 29884807
ANDR EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18487222 16713569 27903893 24480624 10779504 32668201 28549433 23172223 34585037 23518348
EP300 PRKDC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
EP300 RAD50 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 16051665
HDAC1 ERCC6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31722399 26496610 26030138
SRC GRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 16713569 11964172 9016807 12624098
MYC HDAC3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23079660 31155734 22002311 18483244
ROA1 NONO â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 25324306 22446626
ESR1 NONO â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33731348 25604459 31527615 20348541
NONO PIN1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16055720 16189514 16713569 25416956
NONO SPI1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8626664
PARP1 HDAC2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 16204234 20596014
CFTR PRKDC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
TOP1 PRKDC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28415827 15848144
PPP1CC RRP1B â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
SFPQ PSPC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 16148043 33961781 15140795 24981860
SMARCD1 SMARCC1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 34591612
CFTR XRCC5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 31324722 29924966
H2AX XRCC6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 23145133 15613478 33961781 18406329 20224553
PIN1 RAF1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20179103 20179161 15664191
HDAC2 IKZF1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10204490 10357820 30760870 12015313
SIN3A IKZF1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10357820 11959865 12015313
SRC ESR1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 17284441 6169640
FUS ELAV1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27460707 29395067 29884807
DHX9 POLR2A â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
PPP1CA YLPM1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
SFPQ SIN3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
EGFR ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12534934 15288768 15305378
ESR1 MEN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16651450 31527615
PARP1 HDAC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 16204234 20596014 19470756
H2AX PRKDC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20356835 22184063 26095369 15613478 18406329 14627815 20085707
CUL3 PRKDC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26949739
PRKDC ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26175416 15640154
RRP1B ROA1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19710015 26186194
HDAC3 ESR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31527615 16469706 14722073 26487511 20348541
HEY1 HES1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 27129302 26068074 19802006 33961781
ROA1 YLPM1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
HDAC1 NR3C1 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
NCL TOP1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CDK1 SKP2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
ARAF RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31980649 34017080 20130576
ROA1 DDX5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 25324306 22446626 17643375
EGFR RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
EGFR ARRB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
SRC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
CTBP1 KAT2B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15834423 9824164 16122695
MYC HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 22286234 30415952
MYC TOP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 30415952 29467282
LMNA NONO â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22412018 22939629 25948554
ROA1 RBM14 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 22446626 26496610
SFPQ SIN3A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21566083 19339282 17452459 11259580
SNRPA U2AF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32296183 22365833 21516116 25416956
ESR1 ACTB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31527615 20308691 19805454 21182203 21182205 20348541
SRC8 HDAC6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17643370 21847094 21220424 33961781
ELAV1 PTBP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29395067 22365833 17967866
ROA1 PTBP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22446626 25324306 22863883 34079125 22939629 26344197
ELAV1 ROA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22446626 25324306 29931370 26496610 34079125 29395067 19322201
MYC SKP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
SNRPA U2AF2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED19 MED9 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CREBBP HTT â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PARK2 SNCA â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HSPA4 PARK2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HSPA4 SNCA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MED10 MED9 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HDAC2 IKZF1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PIN1 POLR2A â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
SMARCA2 SMARCA4 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PTBP1 SNRPA â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CDK7 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15461668 10949034 31527615
ESR1 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 28065597 20935677 11887937 17284441
RBM14 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11443112 33742100 16713569
FUS EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18509338 30110629 33742100
SKP2 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22770219 18243116 26593157
ROA1 MATR3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29511296 22446626 25324306 26496610 29884807 34079125
SFPQ FUS â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15975576 25192599 26344197
SFPQ TOP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15848144 9756848 24981860
IKZF1 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23752268 16189514 30760870 10357820 12015313 10204490
HDAC5 HDAC3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10869435 10220385 11466315 11931768 11804585 21081666
CFTR LMNA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26618866 31324722 29924966 17110338
ESR1 BTF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31527615 18025262
IKZF1 IKZF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 9155026 26823144 33961781 10204490
ROA1 FUS â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27460707 29884807 25324306 34079125
SRRM1 SRRM2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16159877 9531537 22939629 26344197
MED9 MED29 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 33961781 14638676 24981860
MED19 MED9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 15175163 14638676 33961781 24981860 26186194 21729782
HDAC1 SMARCA4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
FXR1 FXR2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PPP1CA PPP1CB â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ESR1 HSPA4 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
H2AFX PRKDC â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
XRCC5 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
NCL NPM1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
NR3C1 SMARCA4 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
PPP1CB PPP1CC â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ACTB POLR2A â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CREBBP KAT2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
AR KLK3 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC2 SMARCA4 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED10 POLR2A â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
H2AFX PARP1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ANDR CDK7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10734072 21157430
HDAC1 DDX5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20663877 20022962 15298701 19995069 17369852
ROA1 DHX9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22446626 25324306 26496610 22863883 34079125
KAT2B EP300 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8684459 12888487 9267036 12419806 21413932 22384255 20870727 33051058
MATR3 FUS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27460707 27731383 29884807 26496610
MEN1 PSIP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23508102 22327296 18598942
MYC MLH1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12584560 29467282
MYC XRCC6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17314511 30415952 29467282
MYC SKP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23277542 12769844 12963825 26038816 17157259 24259667
H2AX PARP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16377563 20000738 27728808 33961781 28796254 18406329 28242625 16522924 20085707
ROA1 SFPQ â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 20932480 22446626 26344197
SFPQ SNRPA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21566083 34133714 9848648 17507659
HTT VCP â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
RAF1 YWHAE â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
HDAC1 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15640443 11994312 16713569 15835920 26468294 34585037
HDAC1 SPI1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14647463 16331260 11593411
HDAC1 TOP2B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11062478 11136718
HDAC2 CTBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17967884 31041561 16713569 28947780 16036112 10766745 18212045 11022042
ANDR HDAC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12943985 33640491 16469706
SPI1 FUS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 9478924
HDAC5 YWHAE â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
CTNNB1 AR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5216126 12588987
MED10 MED29 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MED10 MED9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 14638676 24882805 33961781 24981860 27684187
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
PPP1CC YLPM1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
NONO SFPQ â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
H2AFX XRCC6 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
MED10 MED19 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED19 MED29 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
EGFR CDK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 23956138 24658140 25402006 18271526 15657067
DDX5 FUS â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
DDX5 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 33742100 12527917
DDX5 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 25604459 12738788 20308691 11250900 21182205 10409727
EP300 DDX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12527917 20663877
SRC EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 17284441 6169640
SOCS3 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24658140 25402006 31980649 12070153
EGFR SRC8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24797263 24658140 25402006 31980649
EGFR HDAC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 24658140 20133936 25402006
MYCN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
FBXW7 MYC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27795300 31569395 35140242 15150404 33494392 15498494 28007894 23750012 31638140 17646408 28209614 16023596 17157259 25716680 20970423 23791182 32021252 30606768 32345600 17873522 33821962 31152129 20848231 32047362 22524983 17314511 25720964 31285543 32350066 33086033 15103331
FBXW7 AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15592418 33824269
FXR2 FXR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 7489725 21653829 8668200 24778252 33961781 24981860 29395067
MYC FXR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
GRB2 IKZF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 32296183 25416956 27107012
MYC KAT2B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15572685 35140242 12660246
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PMS1 MLH1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 11292842 26496610 10748159 25502805 20004149 33961781 17148452
MYC RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 9315742 28628118 28205554
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
MYC PIN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26655473 29467282 15048125 19131971
NDN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26384308 24349431
MYC PTBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20010808
MYC PRKDC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC HDAC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12080043 18414489
MYC SMN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SMARCAD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC LMNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
ANDR NONO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17452459 12810069 16713569
SFPQ NONO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17452459 18042045 11259580 21988832 25959826 30445466 12403470 31815296 30725116 34017080 33961781 24981860 17507659 30021884 22939629 26344197
NONO PSPC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 16148043 25416956 22416126 34017080 33961781 24981860 16169070
RRP1B PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 34079125 20926688 19710015
TOP1 PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 34079125 15247263 15848144
PARP1 XRCC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24140708 16490787 16794079 14734561 33961781 30585729 34079125 10400681 17283121
PARP1 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24140708 16490787 21575865 16794079 14734561 21679440 34079125 10400681 17283121 20085707
XRCC5 PRKDC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15941674 10750018 20023628 17308091 15758953 20085707 33005030 10446239 26496610 19303849 20711232 9312071 26446488 15520013 28154079 28345663 16857680 12393188 22404984 21679440 26344197
XRCC6 PRKDC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20711232 21575865 33005030 28345663 15941674 10064605 26496610 26446488 15520013 10750018 8422676 26175416 22939629 17308091 30585729 19303849 21969602
PRKDC VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16140914
SPI1 SAMHD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10570299 7814871 14734612
SFPQ PTBP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 8449401 17507659 11514619 10653975 15975576
SFPQ PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15668243 19339282 19423654
SMARCA4 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 10688647 9590696
SMARCC1 SMARCB1 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24421395
UBR5 PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 12011095
XRCC6 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15910003 19177010 28514442 28035050 14681455 10750018 17159921 25574025 17308091 10984620 11196700 32296183 7699019 33005030 15367688 12145306 19118032 10446239 26496610 19906305 26774286 10207052 21454661 18809223 9488450 26446488 15520013 30021884 22939629 17283121 10219089 10757784 21070772 11493912 21172662 15023334 22863883 22451927 21679440 24981860 10783163 33961781 30585729 26344197
H2AX ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CAND1 CUL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 21778237 12609982 12504026 18173839 22405651
PPP1CB NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19036824
U2AF2 SNRPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25416956 22365833
AURKA PIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23970419
SMN1 ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ESR1 SOCS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16055089 18414489
NR5A1 POU5F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17226773 10692469 15831456
NR5A1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10770490 23358192 9468515
YWHAE RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 8005785 11697890
SRC RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17097642 16189514 7517401 8876196 10205168
PPP1CA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7604263 16630891
CTBP1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 9650586 16189514 23752268 31041561 16713569 28947780 10995736 34147029 18765668 11022042
SIN3A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15695521 28514442 9520398 10640275 14647463 12398767 9150133 10444591 14593184 21258344 12943729 12374985 17956988 11102443 9885572 17962807 26496610 12453419 11171972 16331260 20585571 10220385 25314079 12091390 11931768 17643391 11602581 17827154 12724404 11784859 23752268 18059533 9790534 9804427 26949739 24981860 33961781 19182791 11118440 15451426 12920132 26344197
ESR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17312152 31527615 24051437 33731348 14722073 21182205 15557281 18451880 14506733 15140878
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
HDAC1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9650586 16713569
HDAC3 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16528103 18241676
POU5F1 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23185410 17932422 23433354
TLE1 HES1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8649374 8001118 8687460
HES1 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
IKZF1 HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23990620 16354692 18852286
HES1 COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18759300
CUL3 CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 16449638 22013077 12609982 21145461 22405651 26286618
IKZF1 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20207529 22231443 19818654
SPI1 IL7R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17392277 11869689 12027437
SPI1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16263717
CAND1 SKP2 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
ANDR SRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24728074 15062576 11032808 15466214 15027889
SRC ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24498420 14766010 15604093 11013076 27420286 29720121 12736255 18451880 15140878 23065768 17043237 17627277 7539106 11032808 17363140 20935677 14963108 11564893 12630920 22328528 15020686 15784253 17921256 24051437 10454579 17400812 17284441 16957778
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
AR IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 23859805
KLK3 IGFBP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7538844 10218588
AURKA MYCN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23792191 19111882 27837025 19997598 27728805 25175806
ESR1 AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21761347 21761334 18497064
PPP1CA AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11039908 11551964
MYCN MAD1L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
AR CTNNB1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
ESR1 GJA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15028626 12810571 22962310
ESR1 FOXC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25303530 18414489
AR NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315100 15219414 20610535
AR CYP17A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8994191 21664481 22155568
IKZF1 CTBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
IKZF1 CTBP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21900206 16189514 25416956 16713569 10766745 24722188 27107012
IKZF1 IKZF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17383641
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
PPP1CA NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19036824
PPP1CC NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19036824
PGR PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7113584 8015553 10499541
MED10 MED29 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 24882805 14576168 33961781 24981860 26344197
MED10 MED19 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 12584197 15989967 24882805 14576168 33961781 24981860 21729782 26186194
SMN1 TLE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MED29 MED19 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 24882805 14576168 33961781 24981860 21729782 26186194 26344197
HEY1 COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18759300
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PARP1 XRCC6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
TOP1 TOP2B â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
TLE1 HDAC1 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 19101520 22439931
SRC SRC8 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 9748248 31420536
BANF1 LMNA â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
HDAC3 HDAC5 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CREBBP CTNNB1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
ERCC6 POLR2A â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
FBXW7 MYC â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
SMARCC1 SMARCA4 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 24981860
TLE1 HES1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 18611861 24270405 19321451 8687460 33961781 19956621
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
H2AFX TP53BP1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
SRRM1 SRRM2 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
PSPC1 SFPQ â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
SRC8 GRB2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 16189514 12577067 21706016 19380743 11439336
SMARCB1 SMARCA4 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
POLR2A SMARCA2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219440 17159921
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
SMARCC1 SMARCD1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
POLR2A SMARCA4 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
SMARCA2 SMARCD1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
TCERG1 U2AF2 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
SRC EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 8845374 21573184 25402006 7506422 10075741 19704002 10971656 23175185 10777553 22227249 20935677 20624308 21268077 17158602 24189400 9020193 16713569 22973453 11983694 24658140 28065597 21278788 17284441 7797556 20333651 7527393 10358079
EGFR GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19254954 7518560 31980649 9416834 7592693 23956138 14679214 10085134 7510700 27059931 21706016 25402006 16799092 16729043 8665853 15657067 24797263 12577067 8810325 7650032 11960376 23799367 25187647 8626525 10026169 19289468 18271526 21278786 7506413 17971399 8940013 20124286 11726515 9886492 10595738 24189400 9020117 19531499 20473329 9020193 8662998 8647858 1322798 8887653 10229072 16273093 25754235 31959764 11370743 16713569 21596750 9685397 24658140 31985874 22973453 11896612 20067773 17242169 19836242 8810340 21278788 30544639 7527043 9050991 11408594 8621459
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
SIN3A HDAC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16254079 12398767 21258344 12943729 9885572 9150134 12453419 12493763 14749338 22493095 12082111 25314079 12091390 17827154 12724404 23752268 18059533 9804427 26949739 24981860 15451426 26344197
NONO PSPC1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
SMARCA2 SMARCC1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
AURKA MYCN â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
ACTB SMARCA4 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
SMARCA2 SMARCB1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CDK7 POLR2A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
METTL14 METTL3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCA4 SMARCD1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCB1 SMARCD1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCA4 SMARCC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SMARCA4 SMARCB1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMARCB1 SMARCC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ARAF PPP1CC â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
ARAF PPP1CB â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
SRC ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9020159
YWHAE ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19608861 20936779 25852190 17979178
CDK7 CDK1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11900249 12648680 15703371 16697054 17386261 17884153 19667075 19809470 19847258 7533895
LMNA CDK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22986494 2188731 2344612 2188730
CDK1 BIRC5 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11069302 12124778 12792650 14551205 15279786 15917306 17303408 17466630 17660363 18414028 18590585 19016842 19081073 19586613 19652693 7575488
CDK1 TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14551205 15279786 17243194 17303408 17660363 18414028 18590585 7575488
MYC CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18802399 2237430 8065306 11085504
CDK7 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 85.0 1.0 Omnipath 16565220 18767875 11113184 33657372 27303922 19690332 19667075 15703371 10913154 14988404 1532335 29793495 20360007 7799941 19158392 19664995 33574676 19809470 8548828 7533895 17386261 34489572 26881937 17554681 20068231 18452278 21900495 18669648 12814430 16327805 18691976 15868411 8441405 21778139 25849598 27908669 12459251 1833185 19651622 22263797 19847258 19707596 17924679 20347419 29435156 18220336 34370741 19369195 22505032 21468563 17884153 12663041 22425727 7944411 12648680 11900249 8344251 16697054 31429764 24970150
CDK1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 7575488 18590585 17243194 17303408 21524151 17570479 25607646 29603287 20126263 17660363 30685087 15279786
CDK1 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12202491 17145710 17274640 22367880 18088087 17202132 9122166 97225924 10880350
CDK1 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 16565220 24281185 18676872 11149963 12529428 24478433 19287963 18936249 18949405 16170024 20068231 28536639 16189514 33710603 20462440 29371939 18691976 15894279 12517802 11861764 11069302 33211707 28392503 21765467 23433354 18931693 15735703 34034636 25468890 26918045 32373497
CDK1 SAMHD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 23602554 23972988 26667483 25847232 24586870 24623419
CDK1 UBE2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11953320
CDK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 26573794 12569365 22275373 25704883 17043241 23321516 9725910 24480624 21799006 24424504 28062857 21820033 25950519 28415597 27450452 25691442 21782001
CDK1 GJA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 22960107 23828237 22739962 22737133 17570479 15605363 9472011 24815185 26033246 17629739 16718370
CDK1 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 49.0 1.0 Omnipath 17081983 12058066 27253419 22285574 25908633 20333249 16912078 27553022 19933706 16083285 20068231 27619510 17570479 18669648 7213797 81161106 26536659 11278991 17287340 17924679 15190079 14670079
CDK1 LMNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 19007248 16565220 20166139 17081983 18767875 20393185 23870088 17137347 19413330 18187866 19194518 30190500 19664995 19415658 15302935 7925482 16083285 95010153 24741066 20068231 18452278 18077418 17570479 18491316 18669648 32071079 23427156 2344612 18691976 26922519 17287340 18815303 20068230 19651622 20058876 19691289 17924679 22367880 19165338 19664994 18707149 21389115 16964243 18212344 24556839
CDK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17145710 31980649 8360196 23956138 15901825 28150246 18271526 15657067 24658140 25402006 15302935
CDK7 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 10734072 24424504 25943391 21820033 21157430 28638477
CDK7 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21296877 31306665
CDK7 NR5A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19015234 15523052 17901130 24232453 19995909 26750456 10230405 14596681
CDK7 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 30257348 10949034 15461668 9528769 22879364 12118371 28423697 27748765 15059947 16076840 7491495 12093745 23850489 15528270 7838153
CDK7 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18079403 27197304 26799765 10886368 14662762 16327805 24662513 26748711 25561469 21331744 19667075 18079404 22137580 9130709 20457598 19901026 19450536 20932174
H2AFX CHEK2 â—¼   ENZYMATIC_REACTION ✅ 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
RAD50 CHEK2 â—¼   ENZYMATIC_REACTION ✅ 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
PRKDC CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 77.0 1.0 Omnipath 31959038 12607004 22669845 18948271 16794575 24492479 15829965 23684611 12805407 20406977 26929199 21482692 27818175 20660628 33870196 11668173 21731742 33879618 15618221 11901158 24421316 21099343 12386164 15096610 24415760 12447382 12855706 15213307 16150728 20599567 16024600 17570479 12447371 28750002 34244606 33901880 15367709 26505995 16940182 33747205 11025670 12024051 24844881 15668230 10973490 20713355 33961649 19151762 16936775 16798742 12607003 30001349 18644861 25361978 20305300 11390408 20501833 15361851 16982735 23380594 15674326 17237275 20160490 20498628 33851958 15282313 25550082 31609975 15975956 11085506 12493754
CCDC22 COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
DDX5 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15298701 17369852 20022962
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
YBX1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19036157 17595327 24211838 19648825 17875215 16651443
AR EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15305378 19318561 21613411 19258514 15650253 17242169 18692155 15288768 11556855 20610535
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
PGR EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22542550 8347631 16449295 17074804
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
PRKD1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17081983 3138233 18220336 19369195 18691976 2987962 10523301 2984676 19413330 16083266 17192257 26465157 18669648 15302935
AR EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18358509 12534934 22260327 15288768 18951974
EGFR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19104148 27401557 15371335 16099633 22558232 30747223 12040186 26509276 24816560 12740122 25500543 17318191 19568798 21423209 14585353 34227224 23640056 17496910 17052462 24240237 25164010 14517306 21903109 22200182 16952352 20858269 28035485 9233779
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
EGFR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23956138 23178489 18237807 18789131
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
FBXW7 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15498494 17145710 32047362 28007894 31569395 33821962 20399964 20970423 17157259 16023596 20852628 15103331 15150404
GRB2 RAF1 â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11532940 11777939 11907067 12040186 12175651 12419216 12479806 12566895 12640133 12782630 14585353 14764585 15169888 15516985 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17673906 18039929 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9069260 9510155
GRB2 RAF1 â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11532940 11777939 11907067 12040186 12175651 12419216 12479806 12566895 12640133 12782630 14585353 14764585 15169888 15516985 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17673906 18039929 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9069260 9510155
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
AR KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18945670 20610535 11328859 23095762
KAT2B CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9687573 8684459 9687513 9445475 11864601 9267036 17496784
KAT2B AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504
MEN1 CTNNB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
NCBP2 METTL3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
MLH1 PMS1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 15703371 16612326 16697054 18157157 18406444 19847258 20478261
MLH1 PMS1 â—¼   PROTEIN_INTERACTION 7.0 1.0 ACSN 15703371 16612326 16697054 18157157 18406444 19847258 20478261
MYC PIN1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC PIN1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
PGR MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 8701093 9408078 22396492 9305935 22892083 10651641
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15589822 16857742 14519204 23271972 11983916 11085504
MYC HNRNPA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12747840 20010808 12695333
MYC PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23277454 12695333
MYC NCL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10606642 24951594 12695333 14519204 25018006 11983916
MYC SKP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24259667 12963825 12769844 23792459 21245140 24177224 23277542
MYC AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20890087 20519624 14744757 20682043
MYC BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17170079 19287963 20508797 19602047
MYC HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1534087 14519204 1562593 10446203
CREBBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17303408 15522869 12776737 20144767 17660363 16878156 15279786
SKP2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17145710 24259667 12963825 12769844 17157259 23277542 20852628 16376880 35260179 26038816
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
PIN1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26655473 15048125 30723410 23716601
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
SMARCB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10319872 14559996 14964309 19234532
MYH10 PPP1CB â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
SFPQ NONO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17452459 21988832 17145710 17507659 12403470 11259580 30021884 10858305 18042045 20421735 25959826
NONO TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 10858305 9756848 17481653
AR PARK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12612053 17510388
PARP1 H2AFX â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 12607003 14726013 15175241 15459660 15703371 16581787 16697054 17088286 17116881 17303408 17713585 19208614 19364882 19772495 19847258 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9488723
PARP1 RAD50 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PARP1 H2AFX â—¼   PROTEIN_INTERACTION 31.0 1.0 ACSN 12607003 14726013 15175241 15459660 15703371 16581787 16697054 17088286 17116881 17303408 17713585 19208614 19364882 19772495 19847258 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9488723
PARP1 RAD50 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PARP1 TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 20875401 15911331 15848144 14699148 15247263
PRKDC H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 107.0 1.0 Omnipath 18454178 9488723 19321613 21930799 19305155 25487737 22819196 20493860 17570479 12607005 16673875 26976643 17723002 21151168 16039583 21514376 26438602 19049966 20368801 23916969 16935931 27919340 17923115 16061642 18438399 20157519 20461094 21690091 24253929 19531483 26960975 25168287 18758438 19268590 27813335 25690891 17210576 26748709 18406329 23972723 17412408 34429760 27551505 12692309 29221122 20703100 16861886 25070753 27332952 33691101 33863809 23653357 21283714 16788066 19781914 20205745 20860841 21389100 16148027 20116089 15610743 20192759 20224553 14627815 24893124 10734083 20488183 23185622 18157161 33945602 30573684 12766154 25699710 18755145 27738310 10477747 34504648 16820894 20356835 19014481 20713529 17525342 23671119 26114388 23355489 28790110 23678292 20118229 23166506 33986864 15604242 16377563 20609246 12907603 26119999 25072018 15289343 23891091 25269479 23620287 33731502 22972376 34282773 26578593
H2AFX RAD50 â—¼   PHYSICAL_INTERACTION 73.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15496928 15549137 15655342 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001825 18006705 18087292 18171670 18212739 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20051983 20064462 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
XRCC5 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H2AFX RAD50 â—¼   SHARES_COMPLEX 73.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15496928 15549137 15655342 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001825 18006705 18087292 18171670 18212739 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20051983 20064462 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
H2AFX RAD50 â—¼   ENZYMATIC_REACTION ✅ 73.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15496928 15549137 15655342 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001825 18006705 18087292 18171670 18212739 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20051983 20064462 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
HES1 RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
RNF8 XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
RNF8 TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 18001824 18006705 19203579 19772495
RNF8 H2AFX â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 12607003 15279786 15459660 15496928 15549137 15655342 17303408 17660363 18001825 18006705 18171670 18212739 18583988 18590585 18678709 18678890 18809224 19217833 19270065 19490890 19772495 20021983 20064462 7575488 9407949
RNF8 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19772495 7575488 18590585 17303408 18001824 18678890 18583988 18001825 18678709 12607003 9407949 17660363 18006705 15279786 15459660
SFPQ TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 9756848
AR SMARCA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535 17721441
SMARCB1 SMARCA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10078207 18414052 23540691 20506188 8895581 31759698
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
SMARCA4 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11532957 14964309
SMARCA4 SMARCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10078207 12917342 23540691 9891079 28420882
XRCC5 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H2AX TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 20075863 18001824 21317870 12447390 17024177 18001825 21566653 12607005 12697768 21623170
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
XRCC5 H2AX â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 H2AX â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
RAF1 PPP1CB â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
BHLHE40 BHLHE41 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14672706 16462771 16267380 12624110 15147242
PIN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16713569 11533658
PIN1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19933846 12932319 23487407 15664191
PSIP1 BANF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 9860958 9038339 3032450 16175173 9188609 16291214
CCDC22 CAND1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17183367 21778237 23563313 25355947 17497243 15799966
NR5A1 CYP17A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 22155568 12943735 23358192 9178749 16271033 21467194 23530236 10847589 19007851 11145739 12530662 12765518 11749720 17895316 9029713 16887917 17664281 10098601 15767781 17786540 9851803 20980388 11932209 17053042 9593668 20207836
AR NR5A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 11518799
RAF1 PPP1CC â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
SRC RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 7692235 12551923 7517401 17097642 15258589 9689060 16189514 16630891 10998357 11376654 29063113 8876196 10205168 28846113 12952943 22592532 11134016 15710605 16170185
RAF1 YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19608861 16093354 16041367 11697890 8702721 16189514 25852190 7644510 15459208 17979178
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
NR3C1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15826950 16762839 18762022 18028994
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
HDAC3 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC2 SIN3A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC3 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC2 SIN3A â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC3 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC3 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
CTNNB1 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19778454 17005722 19662654 11517919 16288908
ESR1 RELB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17369819 20034404 19433448
CTNNB1 CREBBP â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
AR CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9822653 15350180 16492776 16344550 11161315 18819102 18031230 20610535
HTT CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11264541 11607033 16456924 15994095 17500595 16713569 10823891
CREBBP CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10769018 21751375 11973335 17410209 18347063 16476742 23273993
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
CREBBP AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20541699 9822653 15691881 12810069 9482849 16713569
AR SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19305643 10454563 18687691 17108144 17079466
SRC AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 28144231 15062576 20570899 25133482 21318111 11032808 25950519 21512132 17525795 12933816 20383201 24728074 24948875 24868554 25547388 19117998 21956655 17045208 15027889 24859991 15466214 26829214 21886458
SRC OCLN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12547828 25377781 12604349 20152177 15782139 16492141 9278444 9592087 24349408 22315516 19017651
SRC PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12637538 28174535 28842658 17804414 12505989
SRC GJA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 24508467 19901323 16492141 21856279 10871288 11514593 10679481 15782139 9592087 16189514 30448479 30095367 19284610 26706150 30323740 27280719 9278444 24670366 15350848 16916748 23718910 22342665 15534005 29587860 23596415
SRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 22605996 16492141 27177845 23824743 25423132 25850673 24816560 27203386 11836526 22515442 26918136 10593980 15782139 9592087 22056988 12571228 17087658 20840866 23640056 21195420 25164010 26453937 9278444 16831887 23476652 12123611 11279024 14517306 21903109 22200182 20026641 22264731 25041845 12408824 22247700
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
SRC SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15212693 12893833 11162638 11744621 28671665 24860424 11078745 12096713
KLK3 IGFBP3 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 8817670 7538844 11751371 7525824 10218588 12379487 7525634 12466191 1383255 17047378
MAPK13 PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19369195 19413330 19135240
PRKD1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 26895471 19141652 29108267
PRKD1 HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 21357900 22865920 28681592 16584705 11114197 25514029 26137861 20621068 19655095 25362149 15367659 11081517
AR CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18535113 18673534 20610535 11916967
AR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 21741601 16713569 12799378 12944908 10809237 23331499 15060161 21071413 21885566 18988627 16428447 11916967 12588987 11792709 10987273 14593076 15256534 22187462
ESR1 PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 3481434 9259323 7649480 18022314 2082192 10830306
ESR1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 12829318 12554765 12446585 11000528 15019994 8043503 23027806 9058379 9717846 18414489 12706304 10835496 16293641 18784357 12761896 8145766 22543272 15743834 8530508 10894148
ESR1 NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22052999 11029009 10690351 14742696 19914929
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
PGR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 22396492 16168121 12612073 11000528 18988627 26153859
AR VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12020745 20610535 14684616 18451309
AR KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 17433535 8626436 11059779 15640443 7686046 11006269 12111703 15368351 24307657 9316650 9719026 11867260 12376473 14767470 16275987 11994312 17075604 20181722 9211894 16342680 12917209 18092350 12648523 17011549 11238180 20069563 10547578 16140973 22245379 12539223 20568894 20103546 18758709 21981678 21541973 12463425 12958311 11894840 19389135 17534890 23662037 15923603 16434977 14517289 22695118 10075669 11377978 16137620 11299734 15131260 21780100 16508948 16425097 22473899 14715080 10625666 18640093 21885566 12670590 14729601 16452400 16081584 10898343 11571582 9044850 15833875 16914734 23884959 15640095 15543614 7514587 12376534 12114445 15557561 18780293 23667504 18829551 12782640 16724108 17426252 11504717 19274665 11034093 17566103 12651911 22179832 21308712 16373397 19013180 22155408 9052414 11532861 17094454 17653089 20709811 22654108 22597536 15514031
NR3C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
AR NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
AR KLK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1712248 19345326 25241761
HNRNPA1 NCBP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10982855 9858549 1906035 9271388
HNRNPA1 PTBP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10982855 9858549 1906035 9271388
PTBP1 NCBP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10982855 9858549 1906035 9271388
NCBP2 METTL14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863