MDM4
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15788536
16163388
|
FOXO1
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15817464
15632117
|
TRIM28
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17942393
|
YWHAQ
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12426317
16713569
|
HSPD1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18266962
|
ITPR1
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0907555106
19706527
|
MAPK1
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217079
15225643
|
AMBRA1
|
BCL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
intact
|
8174954
21358617
|
FOXO1
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15059979
15632117
|
STAT5A
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14695224
14500638
|
MAPK1
|
BCL2
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5217079
15225643
|
BCL2
|
AMBRA1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
8174954
21358617
|
HSP90AA1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18266962
|
MAPK1
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17205132
|
KEAP1
|
DDIT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TP53
|
DDIT4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
19210572
|
TP53
|
DDIT4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
FOXO1
|
MYOD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17717603
17922034
|
FOXO1
|
INS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22968147
21335550
|
EXOC8
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
HSP90AA1
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12799359
11988487
|
GRIN2C
|
HSPD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NFE2L2
|
KEAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
19560419
23850759
|
NFE2L2
|
KEAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
19560419
23850759
|
NFE2L2
|
KEAP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
19560419
23850759
|
LYN
|
ELMO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15952790
23109003
|
MYOD1
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10805738
9988769
|
YWHAH
|
MDM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16511560
5218386
|
YWHAQ
|
MDM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16511560
5218386
|
MDM4
|
TP53
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19521340
7290688
|
MTOR
|
PDPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214238
11438723
|
MTOR
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214238
11438723
|
AKT1
|
MTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
17611497
18954143
|
TP53
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17184779
5219502
|
TP53
|
PRKAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
PRKAB2
|
TP53
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15866171
24874608
|
TP53
|
PRKAA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15866171
24874608
|
TP53
|
PRKAG2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15866171
24874608
|
TP53
|
PRKAG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15866171
24874608
|
TP53
|
PRKAA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15866171
24874608
|
TP53
|
PRKAG3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15866171
24874608
|
TP53
|
PRKAB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15866171
24874608
|
ZBTB16
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24821728
24821727
|
TP53
|
INS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12392301
22242153
|
TP53
|
NFKBIA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10698490
12700242
|
KMT5A
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17707234
20870725
|
UVRAG
|
SH3GLB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7216089
17891140
|
ULK1
|
DYNLL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20921139
|
PRKAA2
|
PRKAG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16943194
8549768
|
DYNLL2
|
DYNC1LI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18535146
10491388
|
DYNLL2
|
AMBRA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20921139
|
STYK1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31696776
|
SH3GLB1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21311563
17891140
|
ZBTB16
|
DPM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
HSPA9
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSPA5
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
ITGB1
|
KMT2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PTEN
|
PDPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11943559
23331499
|
SH3GLB1
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17891140
|
NRBF2
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
28059666
24785657
|
YWHAQ
|
PDPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12177059
5215652
|
PDPK1
|
YWHAH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12177059
|
ELF1
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15337760
15645134
|
CUX1
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
14612449
22422878
|
AKT1
|
ACOT4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
33148467
|
ATF6
|
INS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
21821716
18450959
|
ENPP1
|
INSR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10615944
|
INSR
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12456798
|
NR0B2
|
INS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
21817852
17259388
|
STAT5A
|
INS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11415999
10373481
|
PRKAB1
|
PRKAA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6767403
18480843
|
PRKAB1
|
ULK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21460634
21072212
|
GRIN2C
|
PRKAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
STAT5A
|
DNMT3A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
26059451
|
DNMT3B
|
DNMT3A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20426865
15362956
|
PRMT5
|
YWHAQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
SRSF4
|
SRSF10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
USP11
|
RNF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7998286
20601937
|
ZBTB16
|
COQ6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
GRIN2C
|
CDS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TP53
|
HSPA9
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
5219502
17184779
|
MDM4
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19521340
24445145
|
EEA1
|
RAB5B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
12493736
10491193
|
VAPA
|
RAB5C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
26344197
|
DNMT3A
|
DNMT3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.82
|
STRING
|
36370105
|
IFNA4
|
IFNA7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
NRBF2
|
ULK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
20562859
28059666
|
ATG14
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
MDM4
|
YWHAQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
MTOR
|
ULK1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
21460634
|
RAB5A
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
PTEN
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
AKT1
|
PTEN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
AKT1
|
FOXO1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.85
|
0.85
|
Signor
|
21798082
|
AKT1
|
FOXO1
|
â—¼ RELOCALIZATION
|
✅
|
-
|
0.85
|
0.85
|
Signor
|
18423396
|
CASP8
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16183855
11406564
|
LYN
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8626437
8051175
8910336
31980649
|
EXOC8
|
BECN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
26387716
21241894
|
AKT1
|
PTEN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
12297295
19903340
12077256
28628118
20605778
28205554
10866658
20596030
|
ITPR1
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
24947355
18250332
|
ULK1
|
RB1CC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
8428476
23392225
|
ATG13
|
RB1CC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
ATG101
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
CDK1
|
LYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
HSPA9
|
HSPD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
BAX
|
UVRAG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21597469
30686098
|
BCL2
|
ITPR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
19706527
15613488
|
ULK1
|
MTOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
25686248
23524951
29321306
21460630
|
BECN1
|
AMBRA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
23974797
|
BECN1
|
NRBF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
ATG14
|
NRBF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
PARK2
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
EPM2A
|
NHLRC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
NRBF2
|
PIK3R4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
HSP90AA1
|
HSPA1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
NRBF2
|
PIK3C3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
HSPA9
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
MAPK1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
BECN1
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
29669822
23112296
28628118
28205554
|
BECN1
|
NRBF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
24785657
24849286
20562859
26496610
33961781
26186194
25086043
28059666
|
PGK2
|
PGK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
33961781
|
RAB7A
|
RAB5C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
26344197
|
RAB7A
|
RAB5B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10329441
26344197
|
PRKAA1
|
PRKAG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
BECN1
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
BCL2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
ATG13
|
ATG101
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
8428476
23392225
|
ULK1
|
ATG13
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
27617292
32543267
32668203
23524951
25686248
33450483
20562859
25126726
29196462
18936157
19597335
21460634
23392225
26018823
33499712
32707033
27203176
33422265
30853401
21460630
|
AKT1
|
FOXO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
DYNLL1
|
DYNLL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
EXOC8
|
EXOC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
21241894
33961781
27173435
22939629
26344197
|
INS
|
INSR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
2550426
11278498
29512653
23302862
|
ENPP1
|
INSR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11289049
10615944
|
PRKAG1
|
PRKAB1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
18480843
6767403
|
AMBRA1
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
TP53
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9843217
9733515
9733514
|
ATM
|
USP28
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16901786
|
ATM
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15546863
15899889
|
BECN1
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22498477
21971985
20889974
20010695
23504944
23564079
23168911
25891078
29955058
23822101
32097085
23954414
19959994
28128446
22241963
16179260
23316280
31410188
18641390
29079782
29849149
28682313
27304906
20711182
25984893
22622204
19180116
20622903
33977871
23541952
24034250
22082873
21543763
19347031
31696776
9765397
16713569
24879154
24141421
17446862
24472739
24599950
28431397
20577262
19050071
32820146
21358617
21139567
23479509
|
PDPK1
|
DDIT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
HSP90AA1
|
MYOD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
1406681
18266962
|
LYN
|
STAT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9837784
22509308
8861946
|
LYN
|
ITPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11782428
|
MTOR
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
18566587
25792870
15718470
14970221
24670654
10910062
18505677
29567957
22337773
21177249
26293922
19299511
18566586
30639242
21045808
11438723
22084251
23872070
21343617
22307628
|
PRKAA1
|
MTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
14970221
|
MTOR
|
NRBF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
28059666
|
TP53
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15212714
20097177
18840615
|
RB1CC1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16061648
21775823
|
HSPA1A
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
7811761
16713569
8729618
|
TP53
|
HSPA1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
7811761
16713569
8729618
|
TP53
|
PRKAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17409411
18431400
|
BECN1
|
UVRAG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29313410
19270696
21597469
25275521
32097085
22314358
24956373
23954414
25533187
34386498
32296183
20562859
22081109
18641390
26496610
27621469
31373534
23878393
19270693
24056303
27203177
33977871
24034250
19372752
30686098
30258449
22493499
24879154
25490155
19050071
29866835
18843052
|
UVRAG
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18843052
24785657
|
EXOC2
|
EXOC8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
24056301
33961781
27173435
14525976
22939629
26344197
|
MYOD1
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10973962
16901893
21689744
|
AKT1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16256741
10896934
|
DKK4
|
LRP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
29925589
|
PDPK1
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
9368760
11825911
14500673
10698680
31467278
12149249
27563096
11313365
11278835
22569334
26264872
10226025
32876514
26256536
21775285
11438723
11445557
23397142
|
ALAS1
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
HSPA5
|
ATF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18624755
31226023
|
EEA1
|
RAB5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11493665
16902405
15016378
11870209
10720461
34079125
11718716
9697774
10491193
14600265
20534488
15328530
|
EEA1
|
RAB5C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12493736
25266290
34079125
25114243
|
NRBF2
|
PIK3R4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
28059666
32296183
24785657
|
NR0B1
|
CYP11A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11427738
19188450
9751505
|
HSP90AA1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
PRKAA2
|
PRKAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
AKT1
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
ULK1
|
RB1CC1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
19597335
|
ULK1
|
ATG13
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.91
|
0.91
|
Signor
|
19211835
|
PIK3C3
|
UVRAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
PRKAB2
|
PRKAG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
ATM
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
PRKAB1
|
PRKAG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
ATG14
|
PIK3C3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
MTOR
|
AKT1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.92
|
0.92
|
Signor
|
21592956
|
ULK1
|
ATG13
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
8428476
23392225
|
PRKAA1
|
PRKAB1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.93
|
0.93
|
Signor
|
17728241
|
AKT1
|
PDPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
RAB7A
|
RAB5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
34079125
22939629
10329441
26344197
|
AKT1
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
MTOR
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
BECN1
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
19180116
7014480
|
BCL2
|
BECN1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.95
|
0.95
|
mint
|
8095158
21139567
|
AKT1
|
FOXO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
10358075
25241761
10358014
16076959
31844113
18786403
|
RB1CC1
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
951.0
|
0.95
|
STRING
|
36370105
|
TP53
|
MDM4
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
7290688
19521340
|
TP53
|
MDM4
|
â—¼ COLOCALIZATION
|
✅
|
|
0.96
|
0.96
|
mint
|
7290688
19521340
|
EXOC4
|
EXOC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
22939629
21241894
27173435
26344197
|
RAB5C
|
RAB5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
17353931
26496610
33961781
34079125
|
PRKAB1
|
PRKAG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
PRKAB2
|
PRKAG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
PRKAA2
|
PRKAG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
PRKAA1
|
PRKAG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
ATG13
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
PRKAA1
|
PRKAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
PIGT
|
GPAA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11483512
28514442
12052837
33961781
22939629
|
PRKAA1
|
PRKAG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
BECN1
|
UVRAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
INS
|
INSR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
PRKAA1
|
PRKAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
EEA1
|
RAB5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
BAX
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
ATG101
|
ATG13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
BAX
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
21778226
18981409
15899854
32064756
10620799
21199865
17289999
9194558
8358790
21671007
16642033
21458670
22262057
9388232
10716992
20865015
14980220
9111042
24141421
17097560
15231068
9463381
33961781
17525735
29749471
23479509
26004684
|
EXOC2
|
EXOC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
PRKAB2
|
PRKAG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
GPAA1
|
PIGK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
GPAA1
|
PIGT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PRKAA2
|
PRKAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PRKAA2
|
PRKAG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
EXOC4
|
EXOC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PIGK
|
PIGT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
KEAP1
|
NFE2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
EXOC2
|
EXOC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
PRKAB1
|
PRKAG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
ATG14
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
NDUFS4
|
NDUFV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
MDM4
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NDUFS3
|
NDUFS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NDUFS3
|
NDUFV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
MTOR
|
ATG13
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15755954
16469695
17680028
18000759
18492954
19022819
19151919
19225151
19446321
19568798
19706736
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
ULK1
|
ATG13
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
15197469
19225151
21460630
18936157
27932573
19287211
19597335
27390127
27387056
27203176
25686248
26018823
20562859
23524951
33450483
26687599
19211835
23392225
26138443
25126726
|
MTOR
|
ATG13
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
12150925
18000759
19225151
21157483
17680028
19151919
19864431
26801615
15755954
19446321
19258318
19706736
12408816
19211837
11274345
19211835
19568798
|
ATG101
|
ATG13
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
20562859
23392225
26299944
19287211
24290141
19597335
24100292
|
ATG13
|
RB1CC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
20562859
19225151
23392225
19597335
19211835
|
CDK5
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
12556884
16332722
16858402
17303408
19151707
20724832
21727086
21922195
23589330
23850759
|
CDK5
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17303408
23589330
16858402
19151707
27470939
16332722
12556884
21600237
21922195
|
ATM
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
452.0
|
1.0
|
Omnipath
|
25301947
21720806
23549171
10713094
16501611
15077171
24886358
17570479
19375142
22028490
16916644
14712210
19303885
9407038
11927276
26700820
28356518
15226429
10723129
19788889
12064478
19705844
26673821
22179422
20931131
19062161
27030982
22891162
17157788
19056039
15758953
12049739
15361830
26620371
25865756
22615843
10196661
10656682
11313957
25088203
15140942
12519769
16319535
24469230
12776195
17234789
27511909
29238697
24608431
12927814
16783362
11875057
16436515
22778557
15181149
12702572
10500142
15178764
28842590
28145533
11591448
17855337
22726545
20206688
26824362
21317290
26104798
24704793
9765199
11314044
16906133
17174997
21593792
17967874
10771484
15585169
19625493
15178448
17596534
16288207
15048074
18353733
24057508
19535302
29344296
23708100
29872395
23705030
25043304
33761896
18431490
21404020
15024084
22559321
12151394
24078877
12080066
33982778
16893723
10958792
18289945
27183917
26337656
29170437
18765533
10744722
21748595
18056442
24820418
15489892
16390936
24086335
28140789
23091651
34523970
32001619
23418564
15279808
21317932
21188172
27559048
16818505
17616578
11551930
19010925
11709713
24711418
28654064
18339864
11173129
17486112
10570149
29774100
18381438
21994612
29558908
15258567
9372954
25860929
16858402
33692124
15775976
34107253
19923893
24958101
10436023
14752509
19962312
19071090
26438152
26093282
20123963
22444248
9843217
17525332
15456784
23533526
11780126
20353948
29290977
11096068
28102346
18855897
20372057
24395704
23890999
15725625
15806145
34103468
18345031
16997395
16293623
28477117
19828454
27630139
12071847
22002314
21315088
27177180
12645530
12890678
26113041
15794754
18560558
22099307
9885574
28903382
15665826
24877058
18332866
10611322
24380814
14871840
19934315
22975381
16489034
18406507
21440540
33687951
10608806
23892398
20730097
16914171
15782130
15177184
22055193
18490454
25867001
24349352
18045533
20663147
17535811
20506250
23982736
22375140
15700044
15279774
19266268
24358288
18697815
14729946
20637859
12242661
12771937
17371838
31940492
19409520
10528155
24037342
17257427
11121242
15310764
23148227
28915641
26928575
21423215
11865061
16949371
27810895
18449195
20711232
27389279
22213803
16713569
10446957
22797063
16478990
29048667
15489221
17241873
21187893
21441950
23907539
20005840
9733514
26244501
21614094
12082529
10467728
10714958
32061892
16636671
29147215
10673501
12091386
25202122
21465263
19544417
25823026
24078903
24038750
22198295
21480565
15177039
28182994
28208785
18674635
20183804
18818083
9925639
17712528
15254178
11483158
27940348
26675349
26261212
19717643
12606585
24559687
14871926
23150668
21329876
28153791
12518062
12767922
23824039
11711532
19251701
28118604
15078887
12393500
17456577
20976220
23380594
12519780
20810927
15533933
22420423
17108107
20145032
18032786
18785202
22037398
23184057
31968249
16729035
12588868
21614932
11546806
18614045
14757188
15029243
14968111
22649771
25512053
34496248
18604166
17609585
17976513
16223874
25433195
18985806
9363941
15159397
34282274
29301278
24505404
26056062
23577291
18272544
18715874
19536869
29334356
10801407
15155458
25201202
24376853
19907922
23525106
14643431
28340339
28051100
19085961
15212693
22201816
20026654
16322229
20080565
9733515
15632067
18672098
22577550
25691451
12637545
12548019
11672523
26984736
12324477
16552184
22084686
10864201
14744854
21532626
17118344
19482562
9561848
12511424
17668048
23358251
18511169
21460853
22022355
12939400
21415014
17292432
25651062
23168260
12111733
16648554
30361254
23678107
|
ATM
|
MDM4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
25.0
|
1.0
|
Omnipath
|
20651945
16943424
29065514
16511560
20860841
28690977
17512070
23002429
16163388
16082221
28096294
15788536
|
ATM
|
TRIM28
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
73.0
|
1.0
|
Omnipath
|
25128619
22496453
34194047
30323812
26158765
16862143
28607002
19584288
20858735
28851455
18285803
34419074
17833484
22491012
25404613
21642969
28439615
27364555
27602502
26671524
23096706
23935532
28739276
24754998
25905708
28847822
24461736
23318425
23346550
17178852
27432546
27820601
17942393
21868291
32060145
22205726
25846574
26293668
25533843
23034801
23352131
28249048
23633913
17525332
18657500
24794298
23645696
26212333
23050241
22715096
27376578
23370278
24657165
29540829
25173936
19071136
28847828
20424263
34518220
25956864
23554604
|
BCL2
|
BAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11704864
16227588
17446862
17891140
20709625
21641962
22039431
23064052
23377657
23430059
23850759
7644501
8358790
8929532
9872359
|
BCL2
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11704864
16227588
17446862
17891140
20709625
21641962
22039431
23064052
23377657
23430059
23850759
7644501
8358790
8929532
9872359
|
TP53
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
11278953
12203124
16931621
9582019
17693666
11118038
12433990
11395510
8183578
11429705
10400708
15242522
11423991
19067706
24336083
18381427
22732402
15988033
16341121
10935506
10094833
16215989
17280505
10744634
12851404
20673369
15851483
8845569
10559267
12168779
11850816
19505426
8564971
11756653
19054058
15566940
12173040
17690113
8635454
18034190
10510469
10101800
11335718
23100276
9400998
9445173
9582400
24098340
22532570
9122197
11420692
11104574
15679092
11748232
12560513
11928223
20400479
20546728
17145718
20567883
20840522
18172861
10566557
10777477
7834749
12806965
17521288
19242108
9000137
21859835
|
AKT1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
26763134
14766748
15642728
17525161
|
SH3GLB1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
19074440
11161816
11259440
16189514
16227588
|
BCL2
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
60.0
|
1.0
|
Omnipath
|
17145710
22705850
18981409
9463381
21458670
17097560
17525735
8358790
10620799
26004684
29749471
9388232
21199865
17525161
22262057
21778226
15486085
17289999
9111042
12419244
9194558
15231068
10716992
8183370
14980220
9115213
21671007
16642033
23479509
10677502
|
TP53
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14963330
16151013
7834749
|
BCL2
|
AMBRA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11704864
17446862
21358617
22039431
23064052
23377657
23430059
23850759
8929532
|
BCL2
|
UVRAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
10604474
11704864
16179260
17106237
17446862
17891140
18612260
22039431
22885520
23064052
23377657
23430059
23850759
27754749
8929532
9765397
|
BCL2
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
10604474
11704864
16179260
17106237
17446862
17891140
18612260
22039431
22885520
23064052
23377657
23430059
23850759
27754749
8929532
9765397
|
BCL2
|
AMBRA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11704864
17446862
21358617
22039431
23064052
23377657
23430059
23850759
8929532
|
BCL2
|
UVRAG
|
â—¼ SHARES_COMPLEX
|
|
|
16.0
|
1.0
|
ACSN
|
10604474
11704864
16179260
17106237
17446862
17891140
18612260
22039431
22885520
23064052
23377657
23430059
23850759
27754749
8929532
9765397
|
BCL2
|
BECN1
|
â—¼ SHARES_COMPLEX
|
|
|
16.0
|
1.0
|
ACSN
|
10604474
11704864
16179260
17106237
17446862
17891140
18612260
22039431
22885520
23064052
23377657
23430059
23850759
27754749
8929532
9765397
|
KEAP1
|
BCL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17312394
17884153
18931676
19560419
19622404
19686080
19809470
19818716
19847258
23030059
23850759
|
TP53
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
17693666
8183578
10037739
16738310
18397889
19521340
18487508
21666495
16294215
21656028
22869582
19714248
10744634
8174112
17592775
11782367
19137013
20428827
18682598
11713302
11313951
20501806
9649502
24814047
15767042
24098340
11193470
10329733
21859835
22266868
10953306
19555669
23638218
14684736
19411072
20530667
24155778
8205530
20840522
9000137
15326476
|
TP53
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
12667443
19555669
8205530
19007744
11313951
|
AKT1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
21303971
11882383
17680028
20214616
22094462
20398329
21506126
20028971
12040186
18218901
|
CDK1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
24097825
24677263
23638364
19917720
27231850
11774038
11326318
10766756
|
MAPK1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
9115213
10567572
12039864
10669763
15225643
11323415
21785723
9738012
11337027
10677502
23272207
|
BCL2
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16183855
11406564
|
BCL2
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
72.0
|
1.0
|
Omnipath
|
23504944
17643073
23168911
21971985
19273585
16713569
19050071
16179260
23316280
22205736
23115300
18641390
28128446
17446862
23954414
22241963
23541952
29955058
25891078
29849149
24034250
24599950
9765397
25984893
21358617
18570871
16799551
19180116
20889974
20622903
23564079
19959994
20711182
23479509
19347031
20010695
21543763
22622204
24472739
17438366
|
TP53
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
10825186
11593387
12874009
19472317
10514438
11313928
16807237
8270002
17942917
9275177
20395210
11032828
19861536
12889596
19067706
|
CDK1
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
18408765
18356527
27035875
19473886
24948874
25590687
23029264
19124971
22280365
|
CDK1
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
20937773
|
CDK1
|
KMT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20966048
|
CDK1
|
MDM4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
15735705
|
CDK1
|
GJA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
22960107
23828237
22739962
22737133
17570479
15605363
9472011
24815185
26033246
17629739
16718370
|
CDK1
|
CUX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11584018
17570479
|
CDK1
|
MYOD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
21902831
10942602
17014844
10082583
10764802
9710583
14749395
|
CDK1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
24173284
12767922
1584757
20661218
26029996
2141171
9467949
17570479
20808790
7862459
11327730
11078726
27726420
8357826
16713569
2156209
|
CDK1
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
20513426
26432751
28409123
27680387
28858266
26108642
|
AKT1
|
FOXO1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
15987244
10358075
10102273
12857750
|
FOXO1
|
ALAS1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
10364186
15668399
16122419
19449109
25464856
|
FOXO1
|
CASP8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20200974
19050291
15632117
15565601
|
AKT1
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
90.0
|
1.0
|
Omnipath
|
21440011
10358014
11756412
10358076
31308176
20452955
21798082
11410590
20398329
11311120
11544290
28279977
10217147
15132996
23331499
19216069
11237865
20214616
11463845
16076959
11030146
12228231
9829964
18951090
23180781
17570479
10102273
18593906
17646672
16680151
12456685
18423396
18985696
18988627
17962350
30728292
16670091
18786403
14664696
25241761
16341064
11980723
10358075
2984676
13679577
12560069
10377430
11251083
17680028
2987962
17254970
11864996
20041807
|
MAPK1
|
GORASP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
19651622
17081983
18767875
20068231
17287340
16713569
19413330
11408587
|
HSP90AA1
|
NRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
23220880
30854046
28274957
18039657
16843263
26545934
22046346
23843458
30314968
23948973
|
TP53
|
HSP90AA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15358769
15284248
24451373
18996350
|
HSP90AA1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
12427754
10557093
21460846
16713569
11507088
|
HSP90AA1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
19356729
18266962
10995457
25714412
16189514
12176997
12586360
15843522
|
KEAP1
|
NFE2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
104.0
|
1.0
|
Omnipath
|
30122040
17020408
31257023
35380342
16449638
22245129
18417180
28939422
15475350
24130096
20421418
12145307
32057361
17462537
23727018
24704364
34894983
23857982
19920073
31262713
20599909
36038548
24997453
17015834
23722832
21988832
30778200
24322982
36333711
20486933
30465941
22448038
30576774
21262351
23645672
16888629
31169361
11909699
26078718
25582950
19706542
20463144
16006525
18694732
11439354
15985429
15572695
34815381
28186440
23066931
19560419
15601839
23986495
25628777
27212020
22302998
30793592
16790436
26536456
24512214
17822677
20027226
28533375
22215675
29423025
14517290
32911434
20484052
14585973
18387606
23382044
21383067
32159343
18757741
27091842
24011591
9887101
31941496
22558124
36165926
|
ITGB1
|
LYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
12626562
19161977
19454690
19487819
22470492
9003039
9456329
9763606
9973479
|
LYN
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11413148
17081983
7925280
11641791
9573010
15212693
8617237
|
LYN
|
SLAMF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15315965
15212693
11806999
|
NFE2L2
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19454702
23708697
17467702
21808062
|
MAPK1
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9804779
25241761
18775330
10194762
8226933
10996427
9604935
8388392
12091337
|
MAPK1
|
GJA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
22028470
9535909
19664994
9535905
12637502
15605363
8631994
17570479
|
MAPK1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
14965474
9765199
15116093
21675959
23443559
10781582
25241761
10446957
10958792
11409876
11709713
21147777
10673501
11551930
15867353
11875057
12091386
|
MAPK1
|
CIITA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15210796
17095509
18245089
|
MAPK1
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
24342355
17290218
|
MAPK1
|
ARHGEF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18211802
19261619
|
MAPK1
|
LRP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17496910
18039929
19541618
21965663
20974802
19565474
15547943
12063245
12738796
11226259
|
TP53
|
MDM4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
16492744
18172009
21750655
20036872
21422812
17510313
9926934
18336191
19521340
20372076
10469568
20080970
22290440
21394211
23474762
|
AKT1
|
MDM4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
16163388
18356162
16511560
|
MDM4
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
74.0
|
1.0
|
Omnipath
|
25609649
18677113
28487147
24445145
30045945
20515689
26148237
22266850
11528400
19521340
21088494
16713569
15916963
9226370
12874296
21925390
16024788
25825738
24667498
16227609
24127580
8895579
20174603
18485870
12963717
15604276
25464845
12370303
10608892
23028042
25961923
26186194
17110929
22374672
26876197
17301054
23671280
21965653
17875722
22807444
10075736
19305137
17080083
29023092
27114532
20724842
10827196
19255450
24659749
28035068
23946421
20705607
19075013
21075307
12393902
11223036
|
MTOR
|
IDH3A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
AKT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
45.0
|
1.0
|
ACSN
|
10722653
10949026
11274345
11715018
11756412
11756498
11923280
12408816
12906785
15169778
15808505
16469695
16697215
17052453
17461779
17680028
18000759
18372248
18492954
18570873
18636226
18925875
19022819
19143635
19151919
19568798
19720745
20027184
20138985
20214616
20338997
20398329
20832730
21157483
21474067
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
9812896
|
MTOR
|
ULK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
70.0
|
1.0
|
Omnipath
|
18000759
19225151
21157483
25759175
15755954
28464882
19446321
27681874
26417067
28518135
19706736
24119841
27325266
26906453
27731364
29686608
25026281
27935582
28366635
28674405
27617292
26869683
29507183
25679763
28389629
25686248
19568798
27387347
21383122
26118643
32134989
26887051
12150925
29540819
29849901
10995454
23136410
30093610
19864431
24358342
26844203
29787772
30127742
19690328
21460634
26447757
26589724
21258367
22770472
29057166
29752434
29066806
17680028
19151919
24998849
30174616
26734992
17595159
12408816
11274345
|
MTOR
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
80.0
|
1.0
|
Omnipath
|
18000759
20027184
21157483
11756412
11923280
24670654
16697215
11438723
21592956
20398329
17461779
18372248
21177249
21045808
20338997
15808505
16221682
20138985
20489726
15899889
20214616
8978681
21474067
14970221
19203586
17660512
15718470
19568798
20333297
23006971
15169778
25241761
18566586
19720745
17517883
18925875
22084251
10949026
14761976
11715018
19143635
17277771
18636226
10910062
15047712
9812896
18505677
21343617
19844585
17680028
19151919
18566587
9736715
23872070
10722653
20832730
18570873
17013611
17052453
12408816
15364915
11274345
|
TP53
|
CDK5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
10604467
17591690
12064478
18490454
10500146
|
TP53
|
HLA-DRB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15289308
16230375
11382926
15964798
|
TP53
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12485897
18661553
19763735
|
TP53
|
PTEN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
22957312
15843377
12917634
21637289
17344317
12839924
11545734
18172008
19173293
20554748
19079342
14984207
|
PRKAA1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
28797070
15866171
|
CDK5
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
9372954
21317932
11483158
11740489
19413330
19664995
21600237
11554766
11709713
16552184
10884347
16377624
17591690
15866171
17287340
17967874
92065884
11780126
12064478
10570149
26146988
15701641
17117479
17108107
14702041
|
TP53
|
PTEN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
21336307
18431400
18339852
12620407
17409411
18172008
17823410
16713569
21518799
21483453
|
UVRAG
|
ATG14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
10604474
10949026
11085534
11704864
12667443
16179260
16227588
17106237
17446862
17891140
18097445
18612260
19265852
22039431
22093031
22166994
22421439
22836101
22885520
23030059
23064052
23301705
23377657
23430059
23725295
23850759
24070470
27754749
28645028
8929532
9765397
|
UVRAG
|
PIK3C3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
PIK3R4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
ATG14
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
PIK3R4
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
BECN1
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
10604474
10949026
11085534
11704864
12667443
16179260
16227588
17106237
17446862
17891140
18097445
18612260
19265852
22039431
22093031
22166994
22421439
22836101
22885520
23030059
23064052
23301705
23377657
23430059
23725295
23850759
24070470
27754749
28645028
8929532
9765397
|
UVRAG
|
PIK3C3
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
BECN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10604474
10949026
11085534
11704864
12667443
16179260
16227588
17106237
17446862
17891140
18097445
18612260
19265852
22039431
22093031
22166994
22421439
22836101
22885520
23030059
23064052
23301705
23377657
23430059
23725295
23850759
24070470
27754749
28645028
8929532
9765397
|
UVRAG
|
PIK3C3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
PIK3R4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
ATG14
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
SH3GLB1
|
UVRAG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18032918
17891140
21068542
|
UVRAG
|
PIK3R4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20562859
18957027
|
UVRAG
|
RUBCN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20562859
22423967
21062745
|
UVRAG
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
27203177
17106237
24956373
21311563
19050071
18843052
18641390
21597469
26496610
23954414
22081109
20562859
24034250
32296183
19270696
16799551
19172397
25490155
24056303
|
DYNLL1
|
GALNT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
12447383
23783758
12401177
25233431
11483508
17827179
15483056
|
DYNLL1
|
AMBRA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
27173435
20921139
|
PRKAG1
|
PRKAA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20562859
10698692
26186194
9224708
17012231
16054041
25416956
31515488
32296183
|
CAMKK2
|
PRKAA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
16051629
22561688
21228273
34044797
24959379
17244528
15980064
23716691
25065674
15465812
34421352
12413941
19197243
18692468
33502468
34216621
23863464
34064003
16054096
16054095
15509864
33675805
20538596
19958286
25937278
34290400
34253170
23612973
22304913
|
PRKAA2
|
ULK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21205641
19584320
|
GALNT1
|
DYNLL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
12447383
23783758
12401177
25233431
11483508
17827179
15483056
|
BECN1
|
PIK3C3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
BECN1
|
PIK3R4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
BECN1
|
ATG14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
BECN1
|
PIK3R4
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
BECN1
|
PIK3C3
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
BECN1
|
ATG14
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
AMBRA1
|
BECN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
21358617
22441670
23030059
23377657
23974797
|
VMP1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23316280
19056683
17940279
|
ATG14
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
19270693
19050071
25594178
19223761
18843052
27513923
26496610
23954414
23332761
22081109
20562859
26108642
25891078
24034250
23112296
32296183
24980960
19270696
21062745
20711182
25490155
|
ULK1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
26390974
25545884
28301741
29734735
29233870
30292171
28518135
29313410
24191236
26546165
24848530
25026281
26921696
25026296
25373623
17595159
16940348
26108642
29371398
25891078
23685627
24370004
26008601
28238651
30397185
29233871
24834848
29867359
|
AMBRA1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
20562859
23974797
20711182
20417604
21358617
25438055
23954414
20921139
24587252
17589504
25499913
33562550
|
RUBCN
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
22423967
25594178
22493499
26876213
19270693
19270696
|
BECN1
|
PIK3R4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
20562859
18843052
20711182
18957027
25490155
26496610
19270696
19050071
|
BECN1
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
18628207
36042481
19713971
19050071
16179260
25594178
21936852
18843052
24980959
28128446
25906440
26496610
26783301
23954414
19379691
23332761
20562859
23974797
24034250
16390869
24980960
19270696
25825496
19172397
20711182
23315026
25490155
24472739
17438366
23364696
|
MYF6
|
MYOD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20978076
12500905
7852366
2560751
|
IDH3B
|
IDH3A
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
28514442
16713569
31515270
14681455
33961781
26186194
10601238
14555658
|
PTEN
|
AKT1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
22.0
|
1.0
|
ACSN
|
10753747
11747822
12040186
15721744
16288286
16982858
17218262
17409395
19440036
19847259
19945467
20609352
21084277
22179046
22465479
23732914
24030100
24254977
25364523
26597054
27328425
27572739
|
AKT1
|
PTEN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
19903340
15987703
10790335
20596030
10592173
20605778
10866658
12077256
11035045
16107342
12297295
|
NDUFS4
|
NDUFS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS4
|
NDUFS3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFS3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFS4
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
PIK3C3
|
ATG14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
ATG14
|
PIK3R4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
PIK3C3
|
ATG14
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
ATG14
|
PIK3R4
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
ULK1
|
ATG14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
27938392
29371398
30397185
23685627
29313410
|
ATG14
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18843052
19270693
22493499
19050071
|
PIK3C3
|
PIK3R4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
PIK3C3
|
PIK3R4
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
RUBCN
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
19270693
22423967
21062745
|
CDK5
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
26108642
20513426
27680387
28858266
27406233
|
PIK3R4
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20562859
27411398
8999962
18957027
21575909
|
PDPK1
|
AKT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
11687500
11747822
12670391
15802604
17680028
18802401
19109239
19122654
|
PDPK1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
156.0
|
1.0
|
Omnipath
|
15505410
12538620
12176337
19951971
24352480
11752451
19401591
11369519
10698680
10601311
15718470
24950409
20481595
24169049
10570282
16798838
14993273
11500365
9368760
19844585
17680028
7637810
9169478
26256536
7722458
9094314
12750173
11438723
18802401
9252186
23331499
18456494
9104825
10592173
16189514
20361045
18988627
11278835
20163786
20333297
20041157
12808134
19602588
8630736
10207050
11241670
10438924
9868760
25912234
20153221
25582703
11445557
21775285
12149249
14666721
18596232
9512493
23397142
11809791
12167717
21798082
16033886
10679787
16787925
29562639
15550174
21071413
8978681
10833263
19203586
10226025
26937223
14500673
20161206
11136732
11825911
11042193
9642236
22569334
18662999
9736715
12242303
11313365
11598012
11134526
|
STAT5A
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24218138
24469394
18042802
20385773
|
INS
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
29432553
23912456
11679435
23866690
17335965
24646332
23798298
|
AKT1
|
ITPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
24947355
18250332
16332683
18955969
|
AKT1
|
PRKAA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
19376078
16340011
16083285
26506913
27784766
24467442
|
AKT1
|
YWHAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
20138985
15169778
9812896
17680028
11756412
11923280
20214616
16697215
10949026
10722653
20832730
18570873
18372248
11715018
20398329
17052453
18636226
15808505
|
AKT1
|
YWHAH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
20138985
15169778
9812896
17680028
11756412
11923280
20214616
16697215
10949026
10722653
20832730
18570873
18372248
11715018
20398329
17052453
18636226
15808505
|
CDK5
|
CAMKK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
22778263
21669867
|
ULK1
|
AMBRA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23524951
25438055
20921139
|
ATF6
|
GALNT3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
17991856
18360008
23850759
26587781
|
ATF6
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
19667116
22189555
10856300
19622751
20165829
10866666
17117415
12076252
14973138
15899857
17241871
20801537
11256944
16452489
17522056
10564271
12713871
|
INS
|
INSR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
8393875
21743783
21317886
24296476
26374090
29069585
26245346
16956584
19902173
20332342
23363978
23331499
18988627
23302862
22832498
2550426
15870194
11278498
19752148
29512653
23304064
24633815
17227660
22521887
23223021
30197476
|
CUX1
|
STAT5A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
21330321
14660670
17698633
10935490
|
RAB5A
|
EEA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
15328530
17145710
20534488
14600265
11718716
10491193
11493665
11870209
16902405
15016378
10720461
9697774
|
RAB5C
|
EEA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
25266290
12493736
25114243
|
NHLRC1
|
EPM2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
26546463
21505799
22578008
16115820
26648032
23922729
15930137
18617530
|
PRKAA1
|
PRKAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
20562859
17145710
18480843
8626596
17728241
21232561
16306228
8663446
25852190
8621713
23455922
|
CAMKK2
|
PRKAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16054096
16054095
15509864
19197243
17244528
18692468
15980064
|
CAMKK2
|
PRKAB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16054096
16054095
15509864
19197243
17244528
18692468
15980064
|
CAMKK2
|
PRKAA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
14985505
21918180
8910387
16054096
16054095
15509864
19197243
14614828
23625915
17244528
18692468
15980064
14511394
23583109
|
PRKAA1
|
ULK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
24820971
23372762
28295473
21460634
19584320
21205641
21258367
28389629
34421918
34224814
25980607
32978258
|
YWHAH
|
YWHAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21827211
12657644
12426317
15071501
|
ATG101
|
RB1CC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20562859
23392225
19597335
|
GALNT1
|
DYNC1LI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
12447383
23783758
12401177
25233431
11483508
17827179
15483056
|
ULK1
|
RB1CC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
20562859
19225151
23392225
19597335
25686248
26118643
19211835
|
CAMKK2
|
PRKAG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
16054096
16054095
15509864
19197243
17244528
18692468
15980064
|
CAMKK2
|
PRKAG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16054096
16054095
15509864
19197243
17244528
18692468
15980064
|
CAMKK2
|
PRKAG2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16054096
16054095
15509864
19197243
17244528
18692468
15980064
|