Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
DDX21 EPSTI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DHX9 DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
RPL13 HERC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CTNNB1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPS3A HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSP90AA1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BECN1 KRT18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1225967 23112296
KRT18 BECN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1225967 23112296
MTOR TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PARP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
PARP1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PSMC6 PSMC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16763564 5218720
TP53 PSMC6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11007955 11751459
RRBP1 RPL8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SQSTM1 PRKAG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SQSTM1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MAP1LC3A SQSTM1 â—¼   COLOCALIZATION 2.0 0.8 intact 19427866 7034152
SSBP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19066201
STAT3 IL24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19535621 18941194
STAT3 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15677471 23874455
PPP1CA STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19440292
TP53 TOPORS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219611 17290218
TP53 PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
PRKAB2 TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 PRKAA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 PRKAG2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 PRKAG1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 PRKAA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 PRKAB1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 SCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
PCM1 KRT19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LRRC59 RPL8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GABARAPL2 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RNF20 BRK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LARP4B PABPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20573744
CALCOCO2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HSP90AB1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 TRIM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
TRAF2 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
RB1 HDAC1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PPP1CA HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17008050
PINK1 MAP1LC3B â—¼   COLOCALIZATION 2.0 0.8 intact 20153330 7557104
CTNNB1 VHL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16983094 0606850103
ANKRD26 CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
UBC TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18636086 6804508
UBC NBR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19427866 7034152
STAMBP UBC â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
UBC NBR1 â—¼   COLOCALIZATION 2.0 0.8 intact 19427866 7034152
RPL4 RPL28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RPL13 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NBR1 MAP1LC3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19427866 7034152
NBR1 MAP1LC3A â—¼   COLOCALIZATION 2.0 0.8 intact 19427866 7034152
TNRC6A PABPC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21063388 8089941
CUX1 RB1 â—¼   COLOCALIZATION 2.0 0.8 intact 12891711 5216580
HNRNPM FDFT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FDFT1 TMEM43 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RYBP BRK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKAB1 PRKAA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6767403 18480843
HNRNPM TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
GABARAPL1 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TRA2B RBMX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SRSF10 TRA2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PGRMC1 DHCR24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSP90AA1 MAP3K5 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
EBP LRRC59 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
HSP90AB1 MAP3K5 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
MTOR STAT3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10660304 24931163 23329839 15522880
UBC SQSTM1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5216530 12857745
EIF4A3 SNRPA1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
EIF3D RPS9 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
VHL DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 21942715
DDX5 DHX9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22365833 26344197
UFL1 EMD â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 32807901
FAF2 EMD â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22119785 34079125
RYBP HERC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26186194 34316702
STAT3 PINK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25814554
FKBP8 UFL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32807901 32877691
UFL1 CKAP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 32807901
BRK1 HSBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 33961781
EMC2 CKAP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26496610 27342126
EMC1 FKBP8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32877691 27342126
CANX RPN2 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
EIF3D RPS3A â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
NBR1 LBR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33226137 33545068
VAPA RPN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26344197
MAP1LC3B NBR1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
GABARAP NBR1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
RPL24 SEC61A1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
RPL14 SEC61A1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
RPL37A SEC61A1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
RPL28 SEC61A1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
PPP1CA RB1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
AGO2 DHX9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17932509 17531811 26902284 19955415
HERC2 EIF3D â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 25476789 29426014 30279242
HERC2 PCM1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25476789 29426014 26638075
LYPD3 MTOR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TRAF2 MTOR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
RBM14 PARP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11443112 16713569
RPTOR FAF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26389662 26186194
EMC1 EMC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 32439656 22119785 26496610 27342126 33961781 26186194
EMC3 EMC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 32439656 22119785 26496610 27342126 33961781 26186194
PRKAB2 TRAF2 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 8153045 21516116
WIPI2 ATG5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 30340022 33961781 24954904 26186194
CANX DDOST â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
EXOC1 DISC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
EMC1 EMC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22119785 33961781 28514442 27342126
LYPD3 GNPAT â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
LYPD3 CKAP4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HSP90AA1 PINK1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
MTOR STAT3 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
OPTN WIPI2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31723608 29133525
LARP4B PABPC1 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
MAP1LC3A NBR1 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
LMAN1 TMED10 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ATXN2L PABPC1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
HDAC1 STAT3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
AGO2 HSP90AA1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
RPS9 SEC61A1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
RHEB MTOR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18550814 16098514 16915281 15854902 33157014 15772076 15878852 25351248
RPTOR RRAGA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 18497260 31601708 23184942 21816923 26582740 33961781 26186194 31601764 33157014 25561175 24337580
HDAC1 STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15653507 22750444 15870198 22116549
RPN2 MLEC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 22988243 33961781 31831667
AGO2 DHX9 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
RPL10 SEC61A1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
PARP1 HDAC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 16204234 20596014 19470756
RRBP1 DISC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31413325 29961565
VAPA FKBP8 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32877691 26496610
VAPA CKAP4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
TBKBP1 TBK1 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5220020 17568778
OFD1 MIB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31462741 26496610
CALCOCO2 TBK1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
RPL4 SEC61A1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
BAP1 UBC â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
RPL8 SEC61A1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
PSMC6 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
NCBP1 RNF20 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
PSMA2 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMA5 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
HERC2 DISC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 90000000 31413325 17043677 33961781
DDRGK1 UFL1 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
HDAC1 VHL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22286234 11641274
TBK1 MIB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31462741 21903422
PIGS PIGT â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 11483512 26496610 33961781 22939629 12802054
AGO2 MOV10 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29395067 17932509 34517762
OFD1 PCM1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 24089205 26496610 26638075
DDX17 DDX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GABARAPL1 SQSTM1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BECN1 NRBF2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ATG14 NRBF2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DDX20 GEMIN5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
RFWD2 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CALCOCO2 UBC â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
RBMX TRA2B â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
PABPC1 TNRC6A â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MAP3K5 TRAF2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
TAX1BP1 UBC â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PTK2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HERC2 NEURL4 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
BECN1 NRBF2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 24785657 24849286 20562859 26496610 33961781 26186194 25086043 28059666
TRA2B RBMX â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32296183 21399644 12165565 22365833 24981860
PCM1 MIB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31462741 26638075 21956701 24121310 25795303 33961781 34079125
TOPORS TP53 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HNRNPF HNRNPUL1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
AGO2 TNRC6B â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
TBK1 TBKBP1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CALCOCO2 MAP1LC3C â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HDAC1 DDX5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20663877 20022962 15298701 19995069 17369852
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
RPTOR RRAGB â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
DDX17 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 15298701 19995069 20663877
BBS4 PCM1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17574030 16189514 18000879 22500027 18772192 19081074 15107855
PRKAG1 PRKAB1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 18480843 6767403
BBS4 PCM1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
RPL3 SEC61A1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
TBK1 TRAF2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
GABARAPL2 SQSTM1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
STAT3 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9880553 10440232 23228483
MTOR RPTOR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16847060 26522726 12604610 19619545 26348909 33378666 20169205 24036451 18570873 24516643 19299511 34031390 22424946 22356909 25940091 12719976 22544753 23263282 12150926 12665511 18505677 17277771 17461779 22493283 19114562 18722121 21071439 18030348 19446321 12718876 12747827 24375676 22258093 16837165 21045808 16962653 18955708 17565979 12408816 15467718 23953116 27043084 23911927 17043309 31601708 21177249 21614075 21795849 16631613 20381137 21321085 23297343 23872070 16354680 19875983 25446900 29059166 24337580 16603397 16183647 34171383 15066126 24403073 25332233 17386266 19145465 25007995 16798736 26678875 15268862 20427287 30865892 16919458 25273559 15459249 18519641 18504440 12150925
PRKAA1 MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14970221
MTOR NRBF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28059666
PSMC5 UBC â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
RHEB RPTOR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16631613 25446900 15854902 33157014 24337580
STAT3 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16107692 23874455 20043094
STAT3 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20830236
STAT3 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18266962 12559950
TP53 HNRNPUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
TP53 TMEM33 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
HNRNPUL1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15907477
RB1CC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16061648 21775823
TP53 PRKAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17409411 18431400
TBK1 OPTN â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 18307994 6492190
OPTN TBK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27086836 25923723 32556086 29395067 27035970 27538435 25803835 26365381 20174559 27620379 30327196 23414517 18307994 31723608 32707033 21903422
PINK1 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20057503
RB1CC1 PTK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10769033
PSMA6 UBC â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
LARS MARS â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
PRKAA1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19217427
PRKAA1 SYN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10880969
TRIM4 TBK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23453971 22619329 24722368
TBK1 AZI2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21931555 14743216 17568778 29395067 14560022 30420664 27620379 29251827 32707033 21903422 23286385
TBK1 CALCOCO2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19820708 21903422
AGO2 DDX20 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14970384 11914277 16189514 17932509
RB1CC1 ULK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19225151 18936157
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
GABARAP SQSTM1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PSMD3 UBC â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PRKAA2 PRKAB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
NBR1 SQSTM1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
AGO2 TNRC6A â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
DYNLL1 GABARAPL2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
RRAGA RRAGB â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
BANF1 EMD â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PINK1 UBC â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
PSMC3 PSMC6 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PSMC3 UBC â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
HDAC1 RB1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
PSMB2 UBC â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
SQSTM1 UBC â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
AZI2 TAX1BP1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
RPL10 RPLP2 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
RPL10 RPS3 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
STAMBP UBC â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
PRKAA1 PRKAB1 â—¼   PHOSPHORYLATION ✅ + 0.93 0.93 Signor 17728241
MAP1LC3B SQSTM1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
MAP1LC3A SQSTM1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
MLEC RPN2 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
PIGS PIGT â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
DHX9 PABPC1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
IARS MARS â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
MTOR RRAGA â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
RPL28 RPS3 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
SQSTM1 MAP1LC3A â—¼   COLOCALIZATION ✅ 0.95 0.95 mint 19427866 7034152
RB1 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 6550000 10779361
TNRC6A AGO2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8202684 21840310
RPL3 RPS3 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
RHEB RPTOR â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
RPN2 STT3A â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
RPL10 RPL28 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
DAD1 STT3A â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
DDOST MLEC â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
CTNNB1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 36950384
DDX17 DDX5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 22365833 15298701 19995069 22863883 33961781 24581491 10837141 22939629
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
TBK1 TRAF2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 14743216 32707033 20449947 20562859 29125880 23007157 27135603 30420664 33961781 10990461 30561431 21903422 32041822
PRKAB1 PRKAG2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
PRKAB2 PRKAG2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
PRKAA2 PRKAG2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PRKAA1 PRKAG2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
C9orf72 WDR41 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
PRKAA1 PRKAB2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
ATG5 ATG12 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11825910 12890687 12482611 17353931 20562859 23202584 31612776 22342342 33961781 28253979 33024031 32129924
IARS LARS â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PRKAA1 PRKAG1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PRKAA1 PRKAB1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MAP1LC3B OPTN â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
OPTN UBC â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RPTOR MTOR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 24036451
MTOR RPTOR â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 21045808 8088164
NBR1 UBC â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
AZI2 TBK1 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
OPTN TBK1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
RPL3 RPLP2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RPL10 RPS9 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RPL13 RPL3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPL24 RPL3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPL3 RPS9 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPL10 RPL24 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPL10 RPL37A â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPLP2 RPS3 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPL28 RPL3 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPL37A RPS3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL10 RPL13 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL13 RPLP2 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL10 RPL3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL14 RPLP2 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL13 RPS3 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RPL24 RPS3 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
MTOR RPTOR â—¼   PHOSPHORYLATION ✅ + 0.98 0.98 Signor 19346248
RPL4 RPS3 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL8 RPS3 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL3 RPL37A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL24 RPL28 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL28 RPL37A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL28 RPS9 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
DAD1 RPN2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
DDOST STT3A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL14 RPS3 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
RPL3 RPL4 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
RPL10 RPL4 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
RPL14 RPL3 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
RPL3 RPL8 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
RPL10 RPL8 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
PSMA5 PSMC5 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PSMB2 PSMD3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL3 RPS3A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL10 RPL14 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL10 RPS3A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL28 RPL4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PRKAB2 PRKAG1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RPS3 RPS9 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS3 RPS3A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PRKAA2 PRKAB2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PRKAA2 PRKAG1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPL28 RPL8 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RRAGB SLC38A9 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PRKAB1 PRKAG1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MTOR RHEB â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA2 PSMD3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EMC1 EMC2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ATG14 BECN1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPL4 RPLP2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPLP2 RPS9 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EMC2 EMC3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ATG12 ATG5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13 RPL8 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13 RPL28 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL24 RPL8 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL24 RPLP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL14 RPS9 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL37A RPS9 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL28 RPLP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DDOST RPN2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMA2 PSMC5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMB2 PSMC5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA6 PSMC5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC3 PSMC5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC5 PSMD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA6 PSMC6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA6 PSMD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA5 PSMD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC3 PSMD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA5 PSMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMB2 PSMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA2 PSMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA6 PSMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL13 RPS9 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL24 RPS9 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL14 RPL28 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL37A RPLP2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL28 RPS3A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL8 RPLP2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPLP2 RPS3A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
DAD1 DDOST â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EMC1 EMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC5 PSMC6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMA5 PSMC6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMA2 PSMC6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMC6 PSMD3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPL4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL24 RPL4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS9 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS3A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPS3A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPL14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPL24 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPL24 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL24 RPS3A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL24 RPL37A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPL37A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPS3A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPL8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL37A RPL8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL8 RPS9 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL8 RPS3A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMB2 PSMC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA2 PSMA5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA2 PSMB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA2 PSMA6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA5 PSMA6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA6 PSMB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA5 PSMB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL14 RPL4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL37A RPL4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL4 RPL8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL13 RPL37A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL37A RPS3A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RRAGA SLC38A9 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS3A RPS9 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
APC CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
APC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 10545404 11166179 8259519 7890674 22083140 27902311 8638126 16212417 16798748 19061640 9286858 15327769 9482734 11533658 22056988 19576224 15327768 17318191 26496610 12628243 15355978 9065403 11712088 25241761 26910375 22682247 9065401 12000790 11707392 20219694 9707618 23840886 15525529 11251183 8628279 19631635 11972058 21664290
DDX5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24219989 15660129 20876186 19626115
DDX5 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15298701 17369852 20022962
BANF1 EMD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25910212 22399800 11792822 25502805 17620012 31515488 32814053 32296183 12163176 11792821 16189514
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
STAT3 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18266962 16189514 12559950
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
MTOR RPTOR â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RPTOR â—¼   SHARES_COMPLEX 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
SQSTM1 MTOR â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15340068 16252010 20531300 21981924 25002027 26587781 28574505
MTOR RPTOR â—¼   ENZYMATIC_REACTION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RPTOR â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
RHEB MTOR â—¼   UP_REGULATES ✅ 7.0 1.0 ACSN 12906785 16636147 17604271 18466115 19022819 19143635 23087689
FKBP8 MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24205284 17991864
RPTOR MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 139.0 1.0 Omnipath 15268862 24403073 20427287 22258093 21321085 19446321 15467718 19875983 17461779 12665511 12719976 16631613 21045808 21177249 23911927 24337580 25446900 24516643 18614546 12718876 12747827 16603397 17043309 18519641 22544753 25007995 27043084 19145465 23953116 19619545 16919458 24375676 15459249 16837165 16847060 25332233 12150926 22424946 26348909 12150925 18955708 20381137 22356909 17386266 17565979 18030348 16354680 20169205 19114562 21071439 27329724 35561222 16798736 15809305 22493283 17277771 15661536 16962653 1683716516603397 17604271 18676370 16183647 18505677 23297343 23872070 24036451 15066126 18570873 21614075 18722121 12408816 17599906
RHEB MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 18670866 18075516 18550814 16631613 18466115 16915281 23331499 15772076 16098514 20006481 15878852 21071413 23272152 19299511 15854902 19487463 20226003 19143635 17604271 16636147 17470430 12906785
MTOR STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 29228628 10660304 22408571 12796477 16740698 18691976 26573296 15522880 27384580 26775702 24423131 26241748 23055980
MTOR ULK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 12150925 19211836 18000759 19225151 21157483 17680028 19151919 19864431 15755954 19446321 19706736 12408816 11274345 19568798
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
RPTOR RRAGA â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
RPTOR FKBP8 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 12150925 15755954 16469695 17991864 19864431 23087689 26159692
RPTOR FKBP8 â—¼   PROTEIN_INTERACTION 7.0 1.0 ACSN 12150925 15755954 16469695 17991864 19864431 23087689 26159692
RPTOR SQSTM1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 12150925 12777372 15340068 15755954 15854902 16252010 16469695 17991864 19299511 19864431 19942859 20484410 20531300 21981924 22025673 23087689 25002027 26159692 26587781 28574505
RHEB RPTOR â—¼   UP_REGULATES ✅ 7.0 1.0 ACSN 12906785 16636147 17604271 18466115 19022819 19143635 23087689
PRKAA1 RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21460634 18439900
RHEB RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17604271 15854902 19299511 16636147 24337580 15878852 17470430 19143635 16631613 12906785 18466115 25446900
PRKAA2 RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 18220336 19369195 18722121 18439900 20083114 19413330 18669648
PRKAB1 RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 18220336 19369195 21460634 18722121 18439900 19413330 18669648
NBR1 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20562859 29343546 16861740 20808283 15802564 24879152 25007327 19250911 12813044 21935636
GABARAPL1 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17580304 20562859 23022382 21691068 25416956 31053714 16189514 32296183 21617041 19250911
MAP1LC3A SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 20061800 23022382 23459205 35044719 22963397 36036324 31053714 21045561 25921531 19250911 17580304 21628531 20204693 28740232 23640897 25686248 24100292 26075355 20562859 22658522 25984893 21460636 16286508 19427866 32296183 23989536 19021777 26268733 22714671 24998849 18653543 31366950 33436498 16169070 23239879 26754771
GABARAPL2 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 17580304 20562859 23022382 17353931 24582747 25416956 33436498 31053714 16189514 32296183 21460636 19250911 21900206
TBK1 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 24818040 25040165 29147513 28655770 31810986 28871090 25505069 32966780 27846364 31444413 27404485 34996837 32835772 24886973 30223576 29930914 29973599 27005665 22921120 25723488 25972374 33084718
MAP1LC3B SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 18083104 23022382 35044719 26413874 25416956 22434781 31053714 24023838 19250911 17580304 23333919 20452972 24668264 28085563 21900206 20562859 20010802 25007327 32296183 33302793 24582747 33436498 16169070
PTK2B STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14963038
TOPORS TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17803295 17290218 11842245 16713569 15247280 10415337 19473992 16122737
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
TP53 PTK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24809783 20515733 21355845 21071137 21269258 18493017 17999388 17725966
TP53 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15052775 15284248 21478269
TP53 MAP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10521394 10446979 19411072 10990460 8956998
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
DYRK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 29296831 21383696 14749479 11740489 20171273 25778922 15843377 33906076 10581258 15750624 15897882 15706352 26236013 24899407 33572115 17906639 20935676 24379358 17386256 15870257 26346493 12427754 34103685 17567906 11101524 17210684 18536714 15381073 19965871 26578795 26087959 28060750 21765464 20673369 34216619 16601678 17380123 33443163 18216278 21642861 15526030 22878263 17349959 16738336 20696760 19882354 16219768 17105820 16793543 17332358 24901999 16247456 24196445 26804244 15657359 27208501 18056705 21765463 23420876 22797063 16377624 19861417 18160537 12676607 20123963 15489221 17591690 20514025 23149944 19857493 17891183 27034505 11780126 21057547 25944899 26341817 17349958 20962272 22525275 19828042 12902982 19465479 15471885 15322239 11495913 12907596 32083004 25915850 20018442 24145406 26029824 21394211 12093737 33872315 20610713 20024960 26113041 20811699 18560558 21660965 16717128 11030628 17107963
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
PPP1CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16501611 16713569 15231748 15178317
PRKAA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28797070 15866171
TP53 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23443559 18431400 11707401 22939624
TP53 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18431400 25241761 15855171 18206965 19857493
ACTR1A DYNLL1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
PRKAG1 PRKAA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20562859 10698692 26186194 9224708 17012231 16054041 25416956 31515488 32296183
NBR1 GABARAPL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20562859 23022382 21620860 19250911
VRK3 BANF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 25899223 24265311 24945635 28927264 24600006 16371512 33744941 16495336
TBK1 OPTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 27247382 29246869 29594070 27035970 21617041 18307994 22364875 29755463 21903422 26376340 29867991 23794264 26101267 26365381 21862579 27538435 25026213 25923723 29282133 29626651 29971063 30294276 30223576 20174559 26266977 23414517 27086836 23178947 22518139 27906974 25803835
NBR1 GABARAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20562859 23022382 21620860 24879152 19250911
BECN1 ATG14 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
BECN1 ATG14 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
ATG14 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 19270693 19050071 25594178 19223761 18843052 27513923 26496610 23954414 23332761 22081109 20562859 26108642 25891078 24034250 23112296 32296183 24980960 19270696 21062745 20711182 25490155
TRAF2 MAP3K5 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TRAF2 MAP3K5 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TRAF2 MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 10688666 18292600 9774977 10523862 16636664 19805025 16713569 17700517 17015619 17724081 15310755
MECOM HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11552981 23858473 16713569 11568182
RHEB FKBP8 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 12906785 17991864 18466115 19022819 19143635 23087689
RHEB FKBP8 â—¼   PROTEIN_INTERACTION 6.0 1.0 ACSN 12906785 17991864 18466115 19022819 19143635 23087689
RHEB FKBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18676370 18658153 17991864 19222999
ATG5 ATG12 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 22093031 22166994 23030059 23301705 23725295 24070470 24257061
ATG5 ATG12 â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 22093031 22166994 23030059 23301705 23725295 24070470 24257061
ATG12 ATG5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11825910 20562859 17145710 12890687 17353931 22342342 9759731 9852036 23202584 11265251 12207896 12482611
PINK1 UBC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24784582 25857750
PTK2B PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9182576 16254240 15247219 16760434 7529876 12960434
BBS4 PCM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17574030 15107855 18000879 22500027 16189514
NBR1 MAP1LC3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23022382 21620860 19427866 19250911 21935636
MAP1LC3B NBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 20562859 23022382 21620860 24879152 19250911
MAP1LC3C NBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20562859 21620860 19250911 23022382
NBR1 GABARAPL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20562859 21620860 19250911 23022382
PPP1CA RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 12202491 8380224 17274640 10773440 9315635 17008050 20694007 8384581 16189514 8380637 10889204 12434308
PRKAA1 PRKAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20562859 17145710 18480843 8626596 17728241 21232561 16306228 8663446 25852190 8621713 23455922
AZI2 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17145710 21903422 19820708 14743216 21931555 14560022
TNRC6B AGO2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 19716330 17932509 24778252 19383768 19470757 19838187 24043833 17891150
ATG101 RB1CC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20562859 23392225 19597335