Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HSP90AA1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HIF1A HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14726529 20068160
JPH3 RHOBTB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VHL HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
HIF1A EGLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
EGLN1 HIF1A â—¼   ENZYMATIC_REACTION ✅ 0.8 0.8 mint 7987706 20840591
EGLN1 HIF1A â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 5217229 15474027
HIF1A EGLN1 â—¼   HYDROXYLATION ✅ 0.8 0.8 mint 5217229 15474027
VHL RBPMS â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17986458 22234250
BHLHE40 RHOBTB3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
VHL EGLN1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22286099 17986458 26215701
CCNE1 CUL3 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
PLIN3 RAB9A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12032303 16189514
RHOBTB3 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
CUL3 CCNE1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31636116 27477274 10500095 17192413
RBX1 VHL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16503656 23401859 33567268 12048197 17353931 15601820 26735018 24469044 30349055 33504946 33137104 12604794 16261165 16325183
HIF1A BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19828020
HIF1A EGLN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24681946 20724477 31763849 15721254 20812988 25974097 16407130 27563096 26611735 29279301 17069766 22946054 15474027 20840591 17442832 33550096 23413029 18264140 25361009 18063574 16511565 34007068 16155211 19604478 17353276
RAB9A PLIN3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18195106 16189514 12032303
HIF1A HSP90AA1 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
EGLN1 HIF1A â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
CUL3 RBX1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 19818716 15448697 12481031 11861641 30349055 25270598 20027226 22405651 26100637 19256485 11311237 19250909 25278611 26286618 20865015 15601839 19617556 29958295 33504946 12684064 24145166
HIF1A VHL â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15082527 11865071 11226425 10944113 14556007 11986208 15527772 17973296 12538644 26735336 24899725 12606543 21358672 24015760 16611863 23401859 18062927 21332579 15805242 19940151 12086861 27281823 23413029 33060856 11292862 24316222 16155211 24857547 22932900 29121446 11292861 12101228 15060148 18047470 16278378 21602890 27320910 12464182 26611735 32589900 18402654 25500545 12050673 18694926 26215701 10878807 25361009 11641274 22351759 34007068 18305400 21316481 11024059 34195792 26037477 34174286 33039559 10823831 26743088 31810986 10353251 15833858 17558023 11566883 23580587 27563096 18985005 19123984 25438054 12682018 18323857 23387829 17442832 33550096 18222538 18426857 17047048 12004076 34230460 23318261 33961781 12808024 21335603 12586829 17353276 11358837 28514442 20724477 16140212 12205091 20049704 16862177 11331613 32535973 15721254 14691445 15385570 10973499 15611064 17981124 28775317 12925778 26496610 17339318 30237125 20458141 20639890 17986458 19147576 28425505 11504942 22369643 18264140 16511565 12351678 14600153 30988076 17132228
CUL3 RBX1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RBX1 HIF1A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 11292861 9122164 10878807 12821933 12101228 11292862 10823831 11504942 11454738 10944113 11358837 11024059
RBX1 CUL3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
RBX1 VHL â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
RBX1 CUL3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
RBX1 VHL â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
RBX1 HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
RBX1 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19847258 19686080 19270156 17884153 19622404 15703371 12648680 11900249 16697054 18931676 19809470 15459660
HIF1A VHL â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
HIF1A LIMD1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11292861 10878807 12821933 11292862 10823831 11504942 11454738 10944113 22286099 11358837
VHL HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
HIF1A EGLN1 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A EGLN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23487784 12839937 22075993 20574527 15563275 19628018 18072750 24558194 22451659 16157596
HIF1A VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12205091 15930297 21887475 22150821 22396654 15962286 23159849 17482131 17140440 16883594
HIF1A EGLN1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 16.0 1.0 Reactome 11292861 15652751 17182618 12615973 12788921 11598268 11292862 21335549 17434750 15474027 15247232 12351678 12912907 15987702 22286099 18337469
EGLN1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19604478 20840591 16511565 23413029 12351678 15474027 22946054 15652751 16407130 25361009 31763849 32755251 16391536 15721254 20724477 24145445 17353276 18264140 26611735
VHL HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 123.0 1.0 Omnipath 17145710 21332579 24857547 12682018 26496610 11292861 11024059 15060148 16278378 12586829 17353276 12004076 12205091 17339318 10823831 11226425 21602890 16862177 15611064 12351678 16140212 11865071 26037477 16611863 10973499 23401859 25361009 11331613 18305400 25438054 14691445 17047048 12538644 22932900 18985005 26735336 21358672 18323857 10878807 19147576 16511565 17973296 23413029 24316222 11986208 12808024 12464182 23318261 22369643 19940151 15721254 20724477 21335603 16391536 23387829 18694926 26743088 14556007 18264140 10353251 15082527 11358837 11292862 11566883 12050673 19123984 17558023 27281823 15805242 11641274 25500545 34174286 24899725 12606543 32535973 17132228 24015760 12086861 11504942 35589690 26215701 22351759 12925778 18222538 17986458 14600153 10944113 23580587 26611735 18426857 20049704