HSP90AA1
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18538669
6550889
|
HIF1A
|
HSP90AA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14726529
20068160
|
JPH3
|
RHOBTB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
VHL
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218395
16511565
|
HIF1A
|
EGLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218395
16511565
|
EGLN1
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
7987706
20840591
|
EGLN1
|
HIF1A
|
â—¼ HYDROXYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5217229
15474027
|
HIF1A
|
EGLN1
|
â—¼ HYDROXYLATION
|
✅
|
|
0.8
|
0.8
|
mint
|
5217229
15474027
|
VHL
|
RBPMS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
17986458
22234250
|
BHLHE40
|
RHOBTB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
VHL
|
EGLN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
22286099
17986458
26215701
|
CCNE1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
PLIN3
|
RAB9A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
12032303
16189514
|
RHOBTB3
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HuRI
|
32296183
|
CUL3
|
CCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
31636116
27477274
10500095
17192413
|
RBX1
|
VHL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16503656
23401859
33567268
12048197
17353931
15601820
26735018
24469044
30349055
33504946
33137104
12604794
16261165
16325183
|
HIF1A
|
BHLHE40
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19828020
|
HIF1A
|
EGLN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24681946
20724477
31763849
15721254
20812988
25974097
16407130
27563096
26611735
29279301
17069766
22946054
15474027
20840591
17442832
33550096
23413029
18264140
25361009
18063574
16511565
34007068
16155211
19604478
17353276
|
RAB9A
|
PLIN3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18195106
16189514
12032303
|
HIF1A
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
EGLN1
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
CUL3
|
RBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
19818716
15448697
12481031
11861641
30349055
25270598
20027226
22405651
26100637
19256485
11311237
19250909
25278611
26286618
20865015
15601839
19617556
29958295
33504946
12684064
24145166
|
HIF1A
|
VHL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
15082527
11865071
11226425
10944113
14556007
11986208
15527772
17973296
12538644
26735336
24899725
12606543
21358672
24015760
16611863
23401859
18062927
21332579
15805242
19940151
12086861
27281823
23413029
33060856
11292862
24316222
16155211
24857547
22932900
29121446
11292861
12101228
15060148
18047470
16278378
21602890
27320910
12464182
26611735
32589900
18402654
25500545
12050673
18694926
26215701
10878807
25361009
11641274
22351759
34007068
18305400
21316481
11024059
34195792
26037477
34174286
33039559
10823831
26743088
31810986
10353251
15833858
17558023
11566883
23580587
27563096
18985005
19123984
25438054
12682018
18323857
23387829
17442832
33550096
18222538
18426857
17047048
12004076
34230460
23318261
33961781
12808024
21335603
12586829
17353276
11358837
28514442
20724477
16140212
12205091
20049704
16862177
11331613
32535973
15721254
14691445
15385570
10973499
15611064
17981124
28775317
12925778
26496610
17339318
30237125
20458141
20639890
17986458
19147576
28425505
11504942
22369643
18264140
16511565
12351678
14600153
30988076
17132228
|
CUL3
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
RBX1
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
11292861
9122164
10878807
12821933
12101228
11292862
10823831
11504942
11454738
10944113
11358837
11024059
|
RBX1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11583996
11900249
12648680
12820959
14744430
15340381
15459660
15688063
15703371
15760909
16498403
16547521
16697054
17312394
17884153
18545270
18931676
19090789
19427028
19560419
19622404
19686080
19809470
19818716
19847258
20006983
20531300
20599425
23030059
23377657
23845861
23850759
27984721
9242610
|
RBX1
|
VHL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18931676
18985005
19622404
19686080
19809470
19847258
|
RBX1
|
CUL3
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
11583996
11900249
12648680
12820959
14744430
15340381
15459660
15688063
15703371
15760909
16498403
16547521
16697054
17312394
17884153
18545270
18931676
19090789
19427028
19560419
19622404
19686080
19809470
19818716
19847258
20006983
20531300
20599425
23030059
23377657
23845861
23850759
27984721
9242610
|
RBX1
|
VHL
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18931676
18985005
19622404
19686080
19809470
19847258
|
RBX1
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18931676
18985005
19622404
19686080
19809470
19847258
|
RBX1
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
19847258
19686080
19270156
17884153
19622404
15703371
12648680
11900249
16697054
18931676
19809470
15459660
|
HIF1A
|
VHL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
HIF1A
|
LIMD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
11292861
10878807
12821933
11292862
10823831
11504942
11454738
10944113
22286099
11358837
|
VHL
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18931676
18985005
19622404
19686080
19809470
19847258
|
HIF1A
|
EGLN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
66.0
|
1.0
|
ACSN
|
10102273
10428030
10428780
10435632
10804084
10823814
11557773
11559532
11744734
11756417
11884613
12402042
12676992
12743597
14672622
14684737
14699081
14762718
15024076
15059920
15199147
15240700
15312748
15369676
15379897
15545625
16110315
16126909
16127144
16517405
16517406
16585195
16782875
16888645
17143338
17418790
17533374
17785433
18054315
18056423
18158893
18718909
19211554
20028863
20427344
20535745
20855962
21051947
21765015
22006996
22841746
22850421
22988108
24006507
25043024
25103413
25732824
7493931
7500013
7508926
8089148
8702901
8955077
9486205
9525945
9707622
|
HIF1A
|
EGLN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23487784
12839937
22075993
20574527
15563275
19628018
18072750
24558194
22451659
16157596
|
HIF1A
|
VHL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12205091
15930297
21887475
22150821
22396654
15962286
23159849
17482131
17140440
16883594
|
HIF1A
|
EGLN1
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
16.0
|
1.0
|
Reactome
|
11292861
15652751
17182618
12615973
12788921
11598268
11292862
21335549
17434750
15474027
15247232
12351678
12912907
15987702
22286099
18337469
|
EGLN1
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
32.0
|
1.0
|
Omnipath
|
19604478
20840591
16511565
23413029
12351678
15474027
22946054
15652751
16407130
25361009
31763849
32755251
16391536
15721254
20724477
24145445
17353276
18264140
26611735
|
VHL
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
123.0
|
1.0
|
Omnipath
|
17145710
21332579
24857547
12682018
26496610
11292861
11024059
15060148
16278378
12586829
17353276
12004076
12205091
17339318
10823831
11226425
21602890
16862177
15611064
12351678
16140212
11865071
26037477
16611863
10973499
23401859
25361009
11331613
18305400
25438054
14691445
17047048
12538644
22932900
18985005
26735336
21358672
18323857
10878807
19147576
16511565
17973296
23413029
24316222
11986208
12808024
12464182
23318261
22369643
19940151
15721254
20724477
21335603
16391536
23387829
18694926
26743088
14556007
18264140
10353251
15082527
11358837
11292862
11566883
12050673
19123984
17558023
27281823
15805242
11641274
25500545
34174286
24899725
12606543
32535973
17132228
24015760
12086861
11504942
35589690
26215701
22351759
12925778
18222538
17986458
14600153
10944113
23580587
26611735
18426857
20049704
|