Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
APAF1 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 5214497 11550094
HSP90AA1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18266962
SOD1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15233914
CASP9 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CASP3 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 12011067 15573119
CASP3 AKT2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
CASP3 EIF2S2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10672017
GORASP2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HSP90AA1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 NFKBIB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IMMT SNAPIN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TRAF2 IRF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15361868 19479062
IRF7 IFNA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19349300 12242290
RHOQ PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9799731
RAC3 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17625931
PAK1 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10385525 10791986
TRAF2 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KARS1 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NAPA SNAP23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SNAP23 NAPA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HSPA8 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IGF2R VAMP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19490898 21421921
IGF2R RAB9A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19490898 21421921
IGF2R RABEPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19490898 21421921
EIF2S2 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JUN MAP2K1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9733728 20353950
RAB7A DNM2 â—¼   COLOCALIZATION 2.0 0.8 intact 20711168 8045116
RTN4 NAPA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LAMTOR2 ATP6V1B2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 25567906 1257132
RAB9A VAMP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19490898 21421921
AHNAK2 ACTR1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RRAGC RRAGA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GSK3B PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6673085 7514173
HSPA8 NFKBIB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PTPN1 RHOB â—¼   COLOCALIZATION 2.0 0.8 intact 14722096 6672086
AKT2 PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11579209
KARS1 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SOD1 KARS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18715867
HSP90B1 VPS13C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMCR8 C9orf72 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
VAPB WASHC2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
VAMP3 RABEPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19490898 21421921
RHOG KLC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
RAB1B RAB7A â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
C9orf72 SMCR8 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 27103069
C9orf72 SMCR8 â—¼   GTPASE_REACTION ✅ 0.81 0.81 mint 27103069
FLCN RRAGC â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
FLCN RRAGA â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
FAF2 EMD â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22119785 34079125
EMD VAPB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 25910212
RHOB EPHA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB NISCH â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
DDX18 RBM28 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
RRP1B DDX18 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20926688 24981860
RRP1B STAU1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 19710015
VAMP3 STX8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 19557002
LYAR DDX54 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 33961781
STX12 BET1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29568061 26344197
RAB5C ARF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26344197
RHOB DDX18 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
FAF2 RAB9A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22119785 34079125
RHOB NSF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB STX7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
SNX3 STX7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 22939629
RHOB RAB7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RAB7A RHOG â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 26496610
VAPA RAB5C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26344197
RAC2 RAC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RHOB CLCN7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RUFY1 RUFY3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RHOB VAMP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB BASP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB ESYT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
GTPBP4 RRP1B â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
STX12 STX8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX8 NSF â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20562859 10683148
IFNA5 IFNA6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX12 VAMP3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TRAF2 GSK3B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 20562859 33961781
SHARPIN RBCK1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 23032186 8410237
VAPB SNX6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SNAP23 VAMP3 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
CHM RABGGTA â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
FLCN LAMTOR3 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
RABGGTA RABGGTB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
STX7 STX8 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
DYNC1LI2 DYNLRB1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
CASP9 CASP3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11242052 8900201 25241761 1067155 15941357 11230124 15507451 18723680 17437405
RHOB PKN1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 31871319 34187934
GDI2 RAB7A â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
SMCR8 WDR41 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
GDI1 RAB6A â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
VAPA IMMT â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26344197 26496610
RAB9A NISCH â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 29568061 23386062
PKN1 TRAF2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32296183 14741690
RAB5C FAF2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
NSF STX7 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 20562859
PLIN3 RAB9A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12032303 16189514
RAB5C STX7 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
RAB7A CKAP4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
VAPA CKAP4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
RAB5C CLCN7 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
RAB5C CKAP4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
RTN4 BCL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11126360 17191123
RBM28 RRP12 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
STAU1 RBM28 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 29395067 33961781
LYAR RRP1B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 20926688 19710015
RRP1B SRP14 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20926688 33961781 19710015
STX7 STX12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
VAMP3 STX7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 34079125 19557002
HPS1 HPS4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12756248 20048159
CASP3 CASP9 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HSP90AA1 HSPA1A â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
DYNC1LI2 DYNLT1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
VAPA VAPB â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RAB5C RAB1B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 26344197
NSF STX12 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20562859 33961781
ARF1 ARF4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
STX7 BET1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 29568061 26344197
RAB7A RAB5C â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 26344197
RAB7A RAB5B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10329441 26344197
STX8 STX7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 11101518 12175335 33961781 26186194 34079125
DYNLT1 RRAGA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
TANK TRAF2 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
GDI1 RAB7A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
JUN BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14623928 17262823 19335069
LAMTOR5 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12773388 10329646 15210107
PKN1 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 17251915 12761180
ARF1 CYTH4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18451304 9707577 10652516
ARF1 TFRC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 22595524 23691193 24376839
JUN RHOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21565167 24636898
RAB9A RABEPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9230071
RAB9A PLIN3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18195106 16189514 12032303
PLIN3 HSPA8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSPA8 ARL13B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
VAPA VAPB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 19515777 16227268 9920726 26496610 33961781 26186194 34079125
KLC2 PIK3R3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KARS1 PIK3R3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
BORCS6 KXD1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
BANF1 EMD â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
GDI1 RAB1B â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
ATP6V1A RRAGC â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
ATP6V1B2 RRAGC â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
ATP6V1A RRAGA â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
ATP6V1B2 LAMTOR1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CHM RAB7A â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
STX12 VPS33A â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
PAK1 RAC3 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
ATP6V1B2 RRAGA â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
RAC3 SOD1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
RAC2 SOD1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
RAB7A VPS33A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
NAPA STX12 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
NAPA STX7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
DDX18 GTPBP4 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ATP6V1A ATP6V1F â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
RHOJ PAK1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 14521508 10967094 32814053 33961781 31871319
LAMTOR3 LAMTOR2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
KLC4 KLC2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 22863883 30217970 26496610
GDI2 RAB1B â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
CASP9 APAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5221774 9390557
RRAGC RRAGA â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 16189514 25567906 21981924 16713569 31601708 21816923 23184942 33961781 26186194 33157014 11073942 28716898 20381137 25561175 24337580 25936802 22424946
NAPA NSF â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
C9orf72 WDR41 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
SMC3 SMC1A â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17112726 21111234 31807710 17349791 26496610 10931856 17113138 18832153 11590136 12759374 30021884 22885700 22939629 9789013 31010829 21880767 11877376 23242214 24981860 27173435 11076961 26344197
TANK TRAF2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 14743216 16189514 16713569 21988832 20562859 10581243 23007157 12005438 33961781 8710854 10759890 28155233 30561431 21903422
GRPEL1 TIMM44 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
C9orf72 SMCR8 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ATP6V1B2 ATP6V1F â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
LAMTOR3 RRAGA â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ATP6V1A ATP6V1B2 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
ATP6V1B2 ATP6V1D â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
ATP6V1D ATP6V1F â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
APAF1 CASP9 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
NUP205 NUP93 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ACTR2 ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ARPC4 ARPC5L â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ATP6V1A ATP6V1D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
LAMTOR1 LAMTOR5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LAMTOR3 LAMTOR5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LAMTOR2 LAMTOR5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LAMTOR5 RRAGA â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LAMTOR5 RRAGC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LAMTOR1 RRAGC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LAMTOR1 RRAGA â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LAMTOR1 LAMTOR3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LAMTOR1 LAMTOR2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LAMTOR2 RRAGC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LAMTOR2 LAMTOR3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LAMTOR2 RRAGA â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LAMTOR3 RRAGC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ACTR2 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
PAK1 ACTR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16293614 10467124 14749719 9843499 16702231 10511705 12054568 8625410
CSE1L APAF1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11864614 12522243 14622304 15087373 17377525 18439902
CASP3 APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12874265 21827945 11550094
HSPA1A APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10934467 16713569
APAF1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 17145710 15829969 15024710 9390557 19494828 11113115 10617566 9539746 10364241 10722681 27476169 21060833 19118655 20829884 16977332 10329646 15210107 10393175 16352606 11242052 14555243 10376594 12773388 10206961 19337385 10428850 9488720 19788417 15262985 9922454 21827945 10749135 9651578 19698783 12792650 9837928 11227497
BCL2 TRAF2 â—¼   DOWN_REGULATES ✅ - 8.0 1.0 ACSN 11704864 17446862 22039431 23064052 23377657 23430059 23850759 8929532
CASP3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10409669 9395403 20139069 11948397
MAPK14 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 29050237 16714293 19336399 11495898
MAPK14 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 14970175 33176141 29414778
CASP9 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10708865 9390557 10508159 11230124 18723680 15657060 16977332 15507451 1067155 9708736 25241761 8900201 11242052 9765224 17437405 19788417 9812896 12620238 15941357 12181739 19465923 12792650 15725726
AKT2 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9812896 15004527
MAP2K1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12792650 18669648
JUN CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16393119 21135252 8917510 17166846 19622016 11402335 20220142 22853846 17670745 10567390 17496887 19499154 9878062 21474819 17278098 15282324 15467760 15994313 14672732 15574422 22550166 10066798 17637753 20482821 15574764 11745411 11410592 18084253 20037604 12794082 10790372 16860316 24190040 17501623 17477349 19435822 10500157 11432833
GSK3B CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 87.0 1.0 Omnipath 26907733 16944320 27546592 11967263 14663202 8524413 16504004 29969496 19767775 21347341 25142862 11311237 30736789 14597415 25591548 19645770 10385618 20548028 10766840 10929713 23565238 16039586 17570479 18818515 18167338 12615961 12413951 17046823 19071090 18598945 15465828 19374252 26121043 26432751 18319725 12969793 23733133 22922870 24134204 10486203 12459251 15020233 18769147 10910956 11152665 21317297 20537194 22099186 18328826 11124803 17070615 19757160 22470469 23552696 16732330 27695879 29554905 16103118 15075324 14536078 9832503 28090171
JUN CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18813803 19219074 16406505 16880536 16054035 19190345 17000779 17439715 8545107 16396903 11274345 20107231
BANF1 EMD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25910212 22399800 11792822 25502805 17620012 31515488 32814053 32296183 12163176 11792821 16189514
TANK IRF7 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15210742 16281057 14703513 9566918 17157040
MAP2K4 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7914033 7535770 7839144 9808624 7693711 7716521 7997261 12788955 26538579
MAPK14 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 26822034 17726008 21303975 18451303
MAPK14 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15187187 18039929 12738796 11274345 12697810
MAPK14 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12475989 17689131 17570479 25483191
PAK1 NISCH â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 10661401 11062502 11121431 11385609 11907067 12885870 14764585 15157156 15229651 15536084
PAK1 NISCH â—¼   PROTEIN_INTERACTION 10.0 1.0 ACSN 10661401 11062502 11121431 11385609 11907067 12885870 14764585 15157156 15229651 15536084
RAC2 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9705280 23331499 10224076
PAK1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 18593598 27542844 21371233 22105362 22981863 18668521 27169363 12876277 31416844 23331499 33789117 7873542 29551131 28225038 19595712 11435472 9351825 25794709 9416003 21248166 14993270 23701950 18940914 16129686 11948406 23162738
RPA3 SPRTN â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 23042605 16139798 24768535 23042607
SMC1A SMC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TANK TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 20562859 21988832 21903422 8710854 12005438 14743216 10581243 16713569 23007157 10759890
ARF4 RAB1B â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 22013193 20357002 17429068 18524849 16030262 16633337
CHML RABGGTA â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 11675392 22694141 16401880 11141079 8513495 18532927
TRAF2 FADD â—¼   PHYSICAL_INTERACTION 74.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22427918 22955274 23010170 23069999 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 8910423 9488730 9759866
TRAF2 FADD â—¼   SHARES_COMPLEX 74.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22427918 22955274 23010170 23069999 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 8910423 9488730 9759866
TRAF2 FADD â—¼   ENZYMATIC_REACTION ✅ 74.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22427918 22955274 23010170 23069999 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 8910423 9488730 9759866
TRAF2 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
TRAF2 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18855897 11274345 21614932
TRAF2 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
RBCK1 SHARPIN â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845
RBCK1 SHARPIN â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845
IGF2R GCC2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 18195106 25343031 16885419 19620288 18946081 17488291 8440258
PLIN3 IGF2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10908666 9590177
ARF1 TRIP11 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18451304 12383348 15504911 19715559 10189370
JUN LAMTOR2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12738796 17439715 18039929 26587781 8545107
JUN PPARD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15470497 18625220
GSK3B JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 23331499 1846781 25979842 25241761 20537194 21278055 21397588 17482134 1516134 8384355 17570479 16023596 17215518 30086763 92065884 24632621
GDI2 HPS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 23084991 21187289 27246931 22171327 19403694 17671165 11917121 18477474 22511774 17043139 23247405
GDI2 HPS4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 23084991 21187289 27246931 22171327 19403694 17671165 11917121 18477474 22511774 17043139 23247405
GDI1 HPS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 23084991 21187289 27246931 22171327 19403694 17671165 11917121 18477474 22511774 17043139 23247405
GDI1 HPS4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 23084991 21187289 27246931 22171327 19403694 17671165 11917121 18477474 22511774 17043139 23247405
RHOC PKN1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14514689 21351730 10619026 9988689 18006505 24128008
RHOB PKN1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14514689 21351730 10619026 9988689 18006505 24128008
NSF VAMP3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
CHM RABGGTB â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 11675392 22694141 16401880 11141079 8513495 18532927
CHM HPS4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 23084991 21187289 27246931 22171327 19403694 17671165 11917121 18477474 22511774 17043139 23247405
CHM HPS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 23084991 21187289 27246931 22171327 19403694 17671165 11917121 18477474 22511774 17043139 23247405
RHOC MYL9 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 12185584 2966156 8702756 17151359 3839510
RAB9A GCC2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 18195106 25343031 16885419 19620288 18946081 17488291 8440258
MAP2K1 LAMTOR3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 21779496 9733512 12479806 15118098 17178906 15547943
MAP2K1 LAMTOR2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 21779496 9733512 12479806 15118098 17178906 15547943
LAMTOR3 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11266467 15547943 9733512
MAP2K1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17081983 21105670 16964243 14617795 30711629 18547980 8382613 17188038 17192257 15020233
RAB6A ACTR1A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
DYNC1LI2 ACTR1A â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
RRAGA RRAGC â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
AKT2 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 21303971 11882383 17680028 9065430 20214616 22094462 23552696 12434148 20398329 21506126 26051358 16293724 20028971 12040186 9712142 18218901
CHML RABGGTB â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 11675392 22694141 16401880 11141079 8513495 18532927
CHML HPS4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 23084991 21187289 27246931 22171327 19403694 17671165 11917121 18477474 22511774 17043139 23247405
CHML HPS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 23084991 21187289 27246931 22171327 19403694 17671165 11917121 18477474 22511774 17043139 23247405
DYNC1LI2 RAB6A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
VAMP3 GCC2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 18195106 25343031 16885419 19620288 18946081 17488291 8440258
MYL9 RHOB â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 12185584 2966156 8702756 17151359 3839510
RABEPK GCC2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 18195106 25343031 16885419 19620288 18946081 17488291 8440258