Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HGS EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20308550 0911188107
EGFR NRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR KRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR HRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17673906
HGS NEDD4 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 12230472 5215741
TGOLN2 NCSTN â—¼   COLOCALIZATION 2.0 0.8 intact 18201567 6174903
CLN6 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LRRK2 PCNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
LRRK2 RHOA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 21454543
RAC2 RAC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
EGFR EPHA2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24797263 15657067
CDC42 EPHA2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31871319 28628118 28205554
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
LRRK2 CDC42 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
NEDD4 EGFR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19953087 33762435 29455656
EGFR HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HGS NEDD4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 12230472 23602387 25588945 20675381
SPRTN VCP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
EGFR HGS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23477725 12953068 20308550 23153581 23602387 25588945 18508924 15212941
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
EGFR RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
VCP SPRTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 23042607
PCNA SPRTN â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
HGS TSG101 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
EGFR SCAMP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9658162
EGFR HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12953068 17016520
EGFR SCAMP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15144186 9658162
EGFR PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 21220489 24655521 23542172 29140271 28157503 26725162 22238610 25825764 17115032 26719139 28102297 22692198 28666590 25073158 20670598 20587074 23593472 25675097
ITCH YAP1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10940313 11318614 16469705 16861923 18552861 18628966 21107885 21383157