Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GRB2 ACTN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
SYK CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220991 8621719
HTT CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CBL SRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219404 17141222
CBL ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
STAT3 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731598 14966128
HGS EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20308550 0911188107
EGFR RAB7A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18776048 0806158105
EPN1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19054389
EGFR ABCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12196520
DLG4 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SNX7 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
APP GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12485888 5215996
GRB2 ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16729043 5218694
GRB2 KRT18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 EPS15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 KRTAP19-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VPS37C HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
MIF4GD HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HGS KRT18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HGS ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23208550 8428323
HGS NMI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HGS VPS37B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23208550 8428323
HGS KRT19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HGS TADA2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HGS NEDD4 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 12230472 5215741
ARRDC3 HGS â—¼   COLOCALIZATION 2.0 0.8 intact 23208550 8428323
HTT KRT18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KRT18 CD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT18 KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HNRNPM NEDD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NEDD4 ARRDC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23208550 8428323
STX11 PAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SF3B3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IL4R STAT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15261459 23124025
SYK STAT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
STAT3 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17129668
SUMO1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUMO1 TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20016603 25114211
TRAF4 UBA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT UBA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CRX PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19850845 18172122
ARRDC3 ADRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23208550 8428323
ADRB2 ARRDC3 â—¼   COLOCALIZATION 2.0 0.8 intact 23208550 8428323
ABI2 KRT19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HTT KRT19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KRT19 KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GOLGA2 CSTF2T â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
EIF3F FBXO32 â—¼   COLOCALIZATION 2.0 0.8 intact 6613251 18354498
RFX6 DTX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GFAP KRT33B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KRT33B HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
METTL27 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
METTL27 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBQLN2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK1IP1L C1orf94 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRT15 KRT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
VPS37C CEP55 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 6169256 17853893
VPS37C STAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
SYK APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAB APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAB CSNK2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAB TJP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PAX5 YWHAB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14993928 8633077
GJA1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11035005 5213074
SRC ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
SRC ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16432186 0510562103
SRC ADRB2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219452 17170700
TRAF1 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
APP DLG4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20573181 7894075
DLG4 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
APP DLG4 â—¼   COLOCALIZATION 2.0 0.8 intact 20573181 7894075
MAP3K10 DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11152698
HTT RAB11A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 25942483 1002142
TRAF4 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
CEP55 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GOLGA2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GOLGA2 GGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GGA2 TRIM23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
IPO4 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TFG HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
C1orf94 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MED30 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ARFIP2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPATA12 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
COG8 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CEP55 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT CRMP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
HTT APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT VPS4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT CBS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT MAP3K10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 10801775
VPS35 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MARK4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DCTN2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CSNK2A1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EPS15 EPN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6179743 18200045
EPS15L1 EPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9723620
ADRB2 ARRB2 â—¼   COLOCALIZATION 2.0 0.8 intact 23208550 8428323
STAM VPS37B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
ARRB1 ADRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16407241 11171997
CRMP1 EPN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CRMP1 TFG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ABI2 KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HAP1 ANTKMT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ADRB2 RAB14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
ADRB2 BSG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
ADRB2 PRNP â—¼   PROXIMITY 2.0 0.8 intact 28298427 20167430
BFSP2 KRT24 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
KRT38 LMO4 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
AKAP8L CSTF2T â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
BFSP2 KRT14 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
KRT75 TEKT1 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
METTL27 VPS37C â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
KRTAP26-1 SPATA12 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
ADRA2C MKRN3 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
KRTAP19-5 PSMB4 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
AKAP8L PEF1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
AKAP8L TEKT5 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
KRTAP19-5 POU2AF1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
KRT33B LMO4 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
CBL YWHAB â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
EGFR DCTN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
EGFR ARMC8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24189400 23956138
ARRB1 HGS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23208550 20505072
HGS ARRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23208550 20505072
CD4 POGZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NEDD8 SF3B3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24654937 18274552
C11orf1 PEF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
NEDD8 SYK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24654937 18274552
VPS35 WASH1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24980502 29893854
RAB4A VPS52 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 25416956
MED4 HAUS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25416956 25281560
KRT24 KRT3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
LMO4 METTL27 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
PLA2G10 VPS37C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
PEF1 VPS37C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
GJA1 NEDD4 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
ADRA2C KRT34 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
KRT14 KRT86 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
KRT38 HAUS1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29892012 25416956 33961781
NDC80 MED4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 25416956 25281560
ARRB2 SRC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19202075 19122674 11877451 23242524
SPC25 EPS15 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
KRTAP26-1 PLA2G10 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
OCLN TJP2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
KRT24 KRT75 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
BFSP2 BICRAL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
SRC CBL â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 6538879 18273061
SRC CBL â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 5219404 17141222
HGS UBA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19019082 25260751
NEDD4 UBA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18498243 18287095
ARRB1 SRC â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33844281 19202075 16432186 23242524
SRC TRAF1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10635328 15707590
ARRB2 SRC â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
APP PRNP â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
KRTAP19-5 VPS37C â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
KRT18 KRT6A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
KRT26 KRT6A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
SRC GRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 16713569 11964172 9016807 12624098
HGS PAK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11397816 16713569
NMI STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 9989503
RAB7A RAB4A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 10329441 16962593
RAB7A VPS35 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
KRT6A NUP62 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
SPRY2 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 16893902 6169676
TFG GRB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19380743 18624398
HGS DLG4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 12151521
ARRB2 NEDD4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23208550 18544533
BFSP2 KRT37 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
KRT40 KRT6A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
NEDD4 EGFR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19953087 33762435 29455656
EGFR ARRB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
EGFR STAT3 â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 22693070
HGS GGA2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15611048 19019082
NUP62 NUP54 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 16189514 25416956 8045926 27194810 33961781 21516116
DSN1 NDC80 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 26496610 33961781 26186194
DSN1 SPC25 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 26496610 33961781 26186194
EGFR HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DSN1 NDC80 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
KRT39 LMO4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
DSN1 SPC25 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ADRB2 ARRDC3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
KRT25 KRT76 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
KRT33B KRT86 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
KRT38 KRT76 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
KRT76 LMO4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CSTF2 CSTF2T â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
KRT75 NUP62 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
HGS ACTN4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26819309 15772161 22863883
EPS15 GRB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17474147 19109251 7797522
HGS NEDD4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 12230472 23602387 25588945 20675381
KRT19 KRT6A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRT6A UBQLN2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRT16 KRT3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
HAP1 HTT â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
VPS4A VPS4B â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
KRT25 KRT6A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
EGFR EPS15 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
SRC STAT3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
KRT35 KRT75 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRT75 STX11 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRT75 LMO4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRT75 NDC80 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
STAT3 SYK â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
KRT3 KRT39 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRT40 KRT76 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
FOXD4L1 KRT34 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRT26 KRT3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRT14 KRT3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
EPS15 HGS â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
KRT27 KRT76 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRT34 MKRN3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRT27 NDC80 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
POU2AF1 VPS37C â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
MAPK1IP1L VPS37C â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
EGFR ACTN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649 26320552
EGFR PAK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31980649 24658140 12522133 25402006
EGFR HGS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23477725 12953068 20308550 23153581 23602387 25588945 18508924 15212941
EGFR ARRB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
ERBB3 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9756944 24189400 24658140 16729043 11173924
KRT39 KRT76 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRT38 KRT6A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
SRC ADRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11013230 17170700
FLOT1 FLOT2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17113085 30021884 34079125 22939629 24167781 24809731
MED30 MED4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 25281560 12584197 24981860
MED25 MED4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 25281560 14638676
KRT37 KRT76 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRT26 KRT75 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRT3 KRT37 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRT19 KRT3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRT40 KRT75 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRT3 NUP62 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
RAB11A RAB7A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
ADRB2 ARRB2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
KRT75 KRT76 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRT16 KRT76 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
FNDC11 KRT34 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
LMO4 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRT31 KRT76 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRT40 KRT86 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
KRT31 LMO4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRT3 KRT35 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
EGFR CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27059931 7657591 8665853 27903975 15107835 24797263 28791635 9756944 23799367 23175185 28198003 12734385 14505571 20940296 19155296 10635327 15117950 22833562 29629558 12061819 8662998 10086340 33762435 11994282 20877636 32714745 25005938 31182136 19578043 7782294 24714105 10799548 23158001 26055326 33617900 23153581 15210722 25872741 15657067 19947936 10428778 18508924 16969069 17971399 15962011 19531499 25521828 23774213 22976291 31959764 22591401 18255265 15735736 16713569 20562913 17880946 16914641 9890970 22394513 16729043 32114396 17995934 17182860 18319245 18271526 17545148 15383614 25140053 32377695 15465819 33627783 8798643 25754235 15282549 26177020 22266821 16923119 17242169 30544639 12604776 11239464 9130710 19225046 11370743 21772844 16105874 18273061 7592693 23897813 17486068 16246327 23457600 32904620 12803489 31120930 15668240 22203672 23418353 20124286 28541302 33323455 10092522 14627991 15677445 15159412 20308550 16849543 12593795 19836242 9121472 19713535 18316398 11408594
SRC CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29899407 17094785 16713569 18273061 7782294 12941616 10829062 31120930 15135048 17141222 18996392 8635998 11994282 22203672 19861161 16636290
SRC EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 17284441 6169640
ERBB3 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21278786 24189400 27756321 18803307 17148612 25315821 22439932 10527633 23436906 23866081 10572067
EGFR STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 31980649 23956138 20145033 21573184 25402006 15485908 15657067 14966128 9756944 18258752 15284024 24189400 24240702 25754235 24135280 15950906 24658140 12873986 20067773 10358079
STAT3 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18367518 21590492 23504318
EPS15 HGS â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 12551915 27008177 18362181 10809762 10514494 15772161
HGS HAP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 16713569 12021262
SUMO1 RNF4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29180619 32296183 24907272 15707587 23086935 24151981 24844634
SRC STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 21573184 15313931 11294897 8657134 18070987 10918587 12244095 19372587 12626508 8626374 14551213 16713569 8272872 11350938 9566874 12576423 11940572 15735682
KRT25 KRT3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
NUP62 NUP54 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 8153045 21516116
KRT3 KRT33B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
SRC CRMP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SPRY2 SRC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
FBN1 SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CRMP1 SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CIT DLG4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9870943 9870942 16202622
ADRB2 ARRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23208550 24658140 17148612 24561123 27226565
ARRB2 ARRB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24069330 17353931 33961781 17620599
RNF4 SUMO1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BFSP2 KRT27 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
ARRDC3 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT34 KRTAP26-1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT31 KRT75 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT3 KRT75 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT37 KRT86 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT25 KRT86 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT27 VPS37C â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT35 KRT6A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT19 KRT86 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
BFSP2 SERTAD3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CRX VPS37C â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT19 KRT75 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT34 KRT6A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT38 KRT75 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT25 KRT75 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT33B KRT75 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT37 KRT75 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT3 KRT38 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT35 KRT86 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT27 KRT6A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
FLOT1 FLOT2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
KRT27 KRT75 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT39 KRT86 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT3 KRT31 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
BFSP2 KRT31 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRT16 KRT6A â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRT34 LMO4 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRT27 KRT86 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
FNDC11 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
GRB2 SPRY2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
KRT38 KRT86 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRT27 KRT3 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRT16 KRT86 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
EPN1 EPS15 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
ERBB3 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 31862538
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
MYO5A RAB11A â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
KRT31 KRT6A â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRT34 KRT86 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRT31 KRT86 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRT3 KRT34 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
CEACAM6 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRT34 KRT75 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
EGFR STAT3 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CSTF2T UBQLN2 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
CBL SRC â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
VPS4B VPS4A â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 11563910 12594041 33961781 26186194
CBL SYK â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
ERBB3 GRB2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
EGFR EPS15 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 32377695 15701692 16499958 21226813 19109251 10953014 9049247 16429130
GRB2 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5220480 7642581
EGFR CBL â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 16729043 5218694
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
SRC EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 8845374 21573184 25402006 7506422 10075741 19704002 10971656 23175185 10777553 22227249 20935677 20624308 21268077 17158602 24189400 9020193 16713569 22973453 11983694 24658140 28065597 21278788 17284441 7797556 20333651 7527393 10358079
EGFR GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19254954 7518560 31980649 9416834 7592693 23956138 14679214 10085134 7510700 27059931 21706016 25402006 16799092 16729043 8665853 15657067 24797263 12577067 8810325 7650032 11960376 23799367 25187647 8626525 10026169 19289468 18271526 21278786 7506413 17971399 8940013 20124286 11726515 9886492 10595738 24189400 9020117 19531499 20473329 9020193 8662998 8647858 1322798 8887653 10229072 16273093 25754235 31959764 11370743 16713569 21596750 9685397 24658140 31985874 22973453 11896612 20067773 17242169 19836242 8810340 21278788 30544639 7527043 9050991 11408594 8621459
LITAF NEDD4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 27927196 16118794 11042109 33961781 25963657
SPC25 NDC80 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25416956 20360068 15961401 14681455 33961781 24981860 26186194 14699129 34079125 22939629
EPS15 EPN1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15809337 9723620 10791968 18200045 18375383 21115825 16429130
EGFR ERBB3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
ARRDC3 NEDD4 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
CBL SPRY2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NDC80 SPC25 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NUP54 NUP62 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
HGS STAM â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
HGS CBL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
CBL STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 CBL â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 31980649 8649804 8995445 25036637 23799367 11997436 8943292 9242692 10570290 8662998 11399323 10086340 7642581 9108392 20936779 11133830 8626404 17094785 8063801 9129019 8900205 15210722 8621483 25872741 25814554 9178909 16906159 8950973 17971399 10025673 9295052 19380743 9716598 16713569 11964172 9234717 8083187 7537740 8824292 9259313 9311917 7791764 17072306 14725908 33627783 9461587 9434624 9851874 8695851 12839496 17944804 11792427 10204582 8621719 11823423 9541596 33961781 169092 11263968 98621719 28514442 18273061 7592693 9174058 21706016 8995358 9872323 9233773 9367879 7544353 12941616 10829062 20124286 917890 15677445 9092538 10521482 8647120 19836242
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
SRC CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 9525940 7782294 16713569 18273061 10829062 10799548 10934191 12604776 9890970 17570479 9013636 15135048 17094785 25784557 8635998 10092522 12522270 8621719 17141222 16636290 11239464 19861161 11994282 12941616 14739300 22203672 8849724 15212693
INSR CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 11997497 10635327 11994282 12522270 9525940 12604776 10592173 17570479 9102067 15951569 10829062 15212693 11239464
SPRY2 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 21596750 15004239 16479008 18273061 11053437 16893902 15962011 12593796 17974561 12234920 12593795 17255109 20461437 12815057 11983899 20877636 20124286 20622121 16246327
SYK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 72.0 1.0 Omnipath 16289966 15922744 9525940 19419964 11133830 33512474 18273061 10829062 10799548 10540342 10934191 7721825 12435267 11331248 12604776 9890970 11042121 10092522 11997497 12522270 9857068 9988765 15556646 11742985 15536084 8621719 9102067 22880054 10551821 11239464 10617633 11994282 10570266 12881521 9535867 15577829
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR EPS15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17145710 17389395 10953014 24269888 19534553 25260758 19583965 19690332 15951569 9049247 17016520
EGFR ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 23436906 7929151 21278786 24189400 23866081 17148612 12648464 27756321 18803307 10527633 10572067 22439932
EGFR HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12953068 17016520
EGFR STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23956138 12070153 20145033 14967450 20032199 21573184 25402006 10358079 23894143 14966128 24135280 25241761 14963038 24189400 15657067 24658140 15485908 15950906 18258752 31980649 9756944 22693070 12873986 15951569 15284024
SYK GRB2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
HGS GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 SYK â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 SYK â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
SPRY2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11447289 11997436 15173823 17496910
GRB2 SYK â—¼   ENZYMATIC_REACTION ✅ 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
ERBB3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9756944 24189400 11173924 24658140 14967450 16729043
SYK GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11964172 16189514 22267732 10747947
EPS15 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7797522 17474147 19109251
SPRY2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17496910 11447289 10940627 11997436 16189514 12402043 16339969 15173823 16893902
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
GRB2 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12522133
HGS SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 11094085
STAT3 IL4R â—¼   ENZYMATIC_REACTION ✅ 58.0 1.0 ACSN 10347215 10485906 11160275 11371360 11867689 11870632 11875494 12193690 12223527 12401408 12496409 12818165 12907458 14607900 14610620 14670306 15218058 15356132 15465827 15573129 16243976 16413922 16418395 17404308 17485448 18250477 1825141 18776941 19380816 19833085 20093776 20184663 20237412 20406969 20435894 20510870 20580461 20581311 20856220 21372296 21469115 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24030977 24091328 24857661 27216177 28186502 2965306 7512720 7521688 7543512 9834059
STAT3 GFAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19609931 10737606 15816866 14754894 20460434 21833841 11740937 17161614
STAT3 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16084951 18310224 15184887
SYK STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10777558 25416956 21516116 20133729 31515488 16189514 10825200 32296183
SRC STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 19901323 10918587 9305919 8272872 29036202 9344858 12626508 10815799 16497976 15592455 16713569 17389395 12576423 11350938 9484840 11294897 28978186 18070987 12244095 27472461 21690253 23928694 22303479 8657134 11404481 9083098 14963038 8626374 17016520 9566874 10982829 15212693 11940572 11429593 14551213 15037656 15313931 11850821 9154828 9582023
SRC SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7513017 17353363 17570479 16189514 9389695 23100514
NEDD4L SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19917253 26555259 15496141 15231748
SRC SPRY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18683950 15564375 12815057 15637081 16000370 15212693 12593795 18678649 16893902
SRC ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17456469 17456551 16432186
SRC OCLN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12547828 25377781 12604349 20152177 15782139 16492141 9278444 9592087 24349408 22315516 19017651
SRC GJA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 24508467 19901323 16492141 21856279 10871288 11514593 10679481 15782139 9592087 16189514 30448479 30095367 19284610 26706150 30323740 27280719 9278444 24670366 15350848 16916748 23718910 22342665 15534005 29587860 23596415
SRC DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24981431 16990796 14529711 18721130
INSR ADRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 28256297 8910597 8521811 17570479 8557631
RAB4A RAB14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16522682 16154996 14617813 23519112
CSNK2A1 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11877451 32863206
EPS15 EPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 16429130 18375383 35044719 9723620 10393179 18200045 15809337 21115825 10791968
ARRB2 ADRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 23208550 17148612 17666399 24658140 27226565 2163110 24561123 22364396