BAG6
|
TDGF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
COPS6
|
TDGF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SRC
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
MAPK1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
RIF1
|
TDGF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
LCK
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8946678
9973466
|
FYN
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17570479
22043010
|
SRC
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219079
16966330
|
CTNNB1
|
NANOG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
32448362
25921273
|
CTNNB1
|
SOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
24291232
24482235
|
CTNNB1
|
POU5F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
32803659
21295277
|
POU5F1
|
LEFTY1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16954384
17068183
|
POU5F1
|
NANOG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17211451
|
ACVR2B
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
ACVR2A
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9748228
8612709
|
NANOG
|
TDGF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16846370
20549704
|
SOX2
|
NANOG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17211451
|
BMPR1A
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
ACVR2B
|
ACVR1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
ANG
|
TDGF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
GDF9
|
TDGF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
GPC1
|
TDGF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19013461
6797290
|
NR6A1
|
GDF9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19164181
12912906
|
GID8
|
RANBP10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
802.0
|
0.8
|
STRING
|
36370105
|
ACVR1
|
BMP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
ACVR1
|
BMPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
TDGF1
|
IL18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RMD5B
|
WDR26
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27173435
29911972
|
CQ039
|
WDR26
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27173435
29911972
|
CQ039
|
MKLN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31285494
27173435
|
MKLN1
|
ZMY19
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
27173435
|
TDGF1
|
SIL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
TDGF1
|
LRFN3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
TDGF1
|
GLTL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
TDGF1
|
RMD5B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
TDGF1
|
AIP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
ACV1B
|
ACVR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
8612709
26186194
33961781
|
MKLN1
|
WDR26
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31285494
27173435
29911972
|
TDGF1
|
WDR26
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
WDR26
|
ARMC8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
27173435
29911972
|
ZMY19
|
ARMC8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
27173435
29911972
|
CQ039
|
ARMC8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31285494
33961781
27173435
29911972
|
RMD5B
|
ARMC8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
27173435
29911972
|
RBP10
|
ARMC8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
27173435
29911972
|
TDGF1
|
ARMC8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
ARMC8
|
MKLN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
27173435
33961781
17467196
29911972
|
TDGF1
|
MKLN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
TDGF1
|
MAEA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
TDGF1
|
MYCB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
BMPR2
|
BMP6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11401330
10504300
|
TDGF1
|
CT011
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CT011
|
RBP10
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
27173435
26344197
|
TDGF1
|
RMD5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
RMD5A
|
ZMY19
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
29911972
|
TDGF1
|
RBP10
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
TDGF1
|
CQ039
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
TDGF1
|
ZMY19
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
NANOG
|
SOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
LYN
|
HCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
31980649
|
CQ039
|
MAEA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
27173435
29911972
|
MAEA
|
RBP10
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
27173435
29911972
|
ACV1B
|
INHBB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12032389
15196700
11266516
9202237
|
ARMC8
|
MAEA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
SRC
|
LYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
32707033
9169421
18070987
22581261
|
MAEA
|
WDR26
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
31285494
27173435
29911972
|
ARMC8
|
MAEA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
27173435
33961781
17467196
29911972
|
MKLN1
|
MAEA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
27173435
17467196
29911972
|
RMD5A
|
MAEA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
33961781
27173435
26186194
29911972
17467196
|
ACV1B
|
TDGF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28126904
11909953
|
RMND5A
|
TDGF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
BMP7
|
ACVR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8006002
18070108
16189514
|
SOX2
|
WDR26
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
23667531
28794006
|
MAEA
|
RANBP10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
ACVR2B
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
ARMC8
|
GID4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
ARMC8
|
RANBP10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
RBP10
|
WDR26
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
22939629
29911972
27173435
26344197
|
RMD5A
|
WDR26
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
31285494
33961781
27173435
26186194
29911972
|
WDR26
|
CT011
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
22863883
33961781
27173435
29911972
|
ARMC8
|
RMD5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
27173435
26186194
29911972
17467196
|
MKLN1
|
RMD5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
27173435
26186194
29911972
17467196
|
RMD5A
|
RBP10
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
27173435
26186194
29911972
|
RMD5A
|
CQ039
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
31285494
33961781
27173435
26186194
29911972
|
FYN
|
CTNNB1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.87
|
0.87
|
Signor
|
12640114
|
MKLN1
|
RMND5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
LYN
|
FGR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
32707033
31980649
|
BMPR2
|
BMP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
7644468
7791754
|
ARMC8
|
CT011
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
32296183
33961781
27173435
29911972
17467196
|
BMP4
|
BMPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
GID4
|
RMND5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
SRC
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
31980649
19711372
9169421
33961781
16966330
|
TGFBR2
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
8044119
21054789
|
BMPR2
|
ACVR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
7890683
28514442
7791754
|
BMPR2
|
BMP4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28126904
12045205
7673243
7644468
8702914
|
RMD5A
|
RMD5B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
27173435
|
RMND5A
|
WDR26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
GID8
|
WDR26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
ACVR2A
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
MAPK1
|
POU5F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
23024368
|
CTNNB1
|
BMP4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10601040
12782598
15907834
|
GDF11
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12414726
|
ACVR2A
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12682303
9032295
8612709
|
ACVR2B
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
17295905
16446785
|
GID8
|
RMND5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
GID8
|
MAEA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
RANBP10
|
RMND5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
BMP4
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
CT011
|
MAEA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
27173435
33961781
17467196
29911972
|
ARMC8
|
GID8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
ACVR2B
|
GDF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
RANBP10
|
WDR26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
ACVR2A
|
BMP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
FYN
|
YES1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
CT011
|
RMD5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
32296183
33961781
27173435
26186194
29911972
17467196
|
NANOG
|
POU5F1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
MAEA
|
RMND5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
FYN
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
POU5F1
|
SOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
BAG6
|
LCK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
16286920
18055229
20819927
22437870
22863785
23414611
27192565
28900677
|
MAPK1
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
8506364
7499846
8618896
15967991
8226850
8626561
|
MAPK1
|
LRP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17496910
18039929
19541618
21965663
20974802
19565474
15547943
12063245
12738796
11226259
|
BMP7
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
9748228
7790373
12667445
|
BMP7
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11282024
8006002
31619522
122976748006002
16189514
12297674
|
BMP7
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
18342887
16446785
7791754
7644468
|
BMP7
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9748228
23331499
16446785
|
BMP7
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16189514
7791754
12297674
8605097
|
LCK
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9822663
15886116
10849438
12670394
|
FYN
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
20026641
22264731
24511551
25241761
22340496
12640114
25803041
26509276
|
TGFB1
|
TGFBR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR2
|
â—¼ SHARES_COMPLEX
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
IL18
|
TGFBR2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
10.0
|
1.0
|
ACSN
|
10679398
11592085
14504095
14662834
15099563
15802534
26885855
27048821
27066895
9469432
|
TGFB1
|
TGFBR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
122.0
|
1.0
|
Omnipath
|
1310899
22874531
8047140
11279127
22710166
7878020
16424049
17673906
24132110
18922473
22943793
12729750
16446785
20519943
7706250
15761153
7594497
15548370
15761148
15265520
19010789
26194464
7852346
12717440
17768418
19050695
11133108
14557817
11278410
19920116
22949611
22703233
23331499
23070005
20060931
17070508
21614932
1333888
10716993
16572188
20860622
11323414
21900405
12724770
8106553
23034983
26192618
2871107
12809600
11382746
21372296
20538542
16200688
11792802
26201938
24403530
15099563
11013220
17979848
21054789
23784029
15003992
20644162
8515656
7935686
11157754
20856203
18382895
15282297
18855897
9865696
21441952
10678166
16127449
21041659
10026191
22315516
12767520
17404308
19732719
20616810
21071413
17934056
12738796
18423981
21098712
19747910
9311995
15034927
11274345
12154066
18758450
24336330
21278795
26966341
9261125
16474430
15653932
18490733
8242742
19038247
19109155
|
TGFB1
|
SRC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
56.0
|
1.0
|
ACSN
|
10671552
11133108
11348595
11476890
11955436
11967263
12051714
12426320
14557817
15001769
15279786
15548370
16039586
16099633
16371504
16474430
16919435
17143292
17303408
17496910
17517963
17660363
17928543
17934056
17936032
18037882
18590585
19010789
19029934
19109155
19171760
19619488
19734908
19920116
20519943
20644162
20705860
21278795
21666923
21900405
22007144
22174153
22203675
22370635
22674073
22703233
23343194
24023259
25572304
25730849
26552706
27216177
7542250
7575488
7594497
8666229
|
LRP6
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
7641885
15265686
19718039
21602792
210606194
8655584
19705439
19029934
20093472
17430994
21606194
17884187
14747478
22017973
22433869
17143292
20006983
19072724
14704854
25088803
16965538
16443747
22007144
16547521
19020754
20940130
21640127
21087212
17127310
21796133
|
SRC
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
46.0
|
1.0
|
Omnipath
|
22605996
16492141
27177845
23824743
25423132
25850673
24816560
27203386
11836526
22515442
26918136
10593980
15782139
9592087
22056988
12571228
17087658
20840866
23640056
21195420
25164010
26453937
9278444
16831887
23476652
12123611
11279024
14517306
21903109
22200182
20026641
22264731
25041845
12408824
22247700
|
CTNNB1
|
TBXT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10704849
12032083
12234972
14575694
18948405
15292219
15579438
16139800
14557550
10953028
|
POU5F1
|
NANOG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20925113
17506876
16153702
20526341
19829295
22855527
17068183
|
NR6A1
|
POU5F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
11702949
17030610
21608077
24029702
19228964
16166633
|
POU5F1
|
NANOG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
18662995
22745796
15860457
20505756
18537119
19522013
18687992
17272500
18338330
17068183
|
POU5F1
|
TDGF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16846370
20549704
21083502
17068183
|
POU5F1
|
SOX2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20505756
12136102
17324942
15988017
17068183
|
INHBB
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11266516
|
BMPR2
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
7791754
7890683
|
BMP6
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12297674
|
SOX2
|
NANOG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17068183
16153702
21816365
19829295
|
SOX2
|
NANOG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22745796
23939864
15860457
18537119
17324942
19522013
|
INHBB
|
ACVR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11117535
8196624
15123686
8622651
9032295
|
ACVR2A
|
GDF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
GDF9
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12135884
|
TDGF1
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
12682303
|
NODAL
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11952836
|
BMP6
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10504300
|
INHBB
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11266516
1246619011266510
12466190
|
BMP4
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
8702914
23331499
21071413
16446785
12045205
8006002
7673243
7644468
|
BMP4
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
8702914
26330344
20860622
21054789
11241215
8006002
16189514
7644468
|
GDF1
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
INHBB
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11117535
8196624
15123686
8622651
9032295
|
LEFTY2
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11952836
|
INHBB
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9202237
|
GDF11
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
12414726
23331499
1241472616845370
16845371
16446785
|
MSTN
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23829672
11459935
|
BMP6
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
10504300
|
NODAL
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
16446785
11952836
|
ACVR2B
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
23180781
8622651
16446785
12364468
18988627
|
GDF9
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12135884
10712517
|
BMPR2
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18756288
7791754
10712517
|
BMP6
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11401330
12297674
10504300
|
GDF11
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12414726
|
BMP6
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
11401330
10504300
|
GDF9
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
1213588412135880
12135884
|
INHBB
|
ACVR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11117535
8196624
15123686
8622651
9032295
|
INHBB
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
11266516
15196700
12032389
|
INHBB
|
ACVR1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15196700
|
TDGF1
|
GDF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
TDGF1
|
NODAL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
TDGF1
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19874624
11909953
|
GDF1
|
ACVR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
NODAL
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19874624
11952836
|
GDF1
|
ACVR1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
ACVR1C
|
NODAL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
NODAL
|
ACVR1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12606401
15531507
|
CFC1
|
NODAL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
CFC1
|
GDF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|