Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
JAK2 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
STAT1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10558875 22693070
JAK2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
GRB2 UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
UBB TRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF1 RIPK1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 5220954 8612133
TRAF2 BIRC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TRAF1 TRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8565075 5220916
BIRC3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23070005 18485876
STRN4 STRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 STRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 STRN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 SLMAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 SIKE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 SIKE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
BIRC3 RIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21931591 19464198
EGFR JAK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
MK01 TNR1A â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11606045 19850087
UTP15 UTP20 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
TNR1A ATR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PHOCN EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
TNR1A FOXK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A MCRS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BIRC3 SUMO1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30948266 21988832
TNR1A DOLK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
UBB CDC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11046155 10995389
TNR1A JPH1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RABX5 TRAF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A CDC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RABX5 BIRC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A KIF2C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A KHNYN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A STRN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A STRN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A STRN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FGOP2 STRN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
TNR1A UTP20 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A UTP6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TBC15 UTP15 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A UTP15 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A RRP12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A SLMAP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A SIKE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A DPH1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A KC1E â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A RABX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A GRK6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A PHOCN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A TNPO3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A FOXK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A SCAI â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A ZN101 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A IKBL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A GPC5B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A PI42C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A FGOP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A S39A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A KDIS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A TTYH3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A MFSD5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A KIF14 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A VANG1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A VANG2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A TBC15 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A TPC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A ZN865 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A CA112 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A FBX11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A GPC5C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A DHRS7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A FA40A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A THADA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A RN138 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A XPR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
XPR1 KDIS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VANG2 HSP7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STAT1 TNR1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 10848577
TNR1A BIRC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19815541 18939944 15310755 30420664
RIPK2 TNR1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 9642260
PHOCN FGOP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18782753 26496610 19156129
TP4AP NEMO â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 14585990
TNFA NEMO â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34315543 27560715 20005846 27307491 33815386 16603398 23104095 23032186 30420664 30561431 26670046 23032187
TP4AP IKKB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32889079 14585990
TNR1A GRB2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10359574 16189514 19289468
CASPA RIPK1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11002417 12884866
BIRC3 NEMO â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18931663 23524849
TNFL6 TNR1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15659383 12753742
NEMO TNR1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 10755617 30420664 30561431 27552911
BIRC2 UBB â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
SUMO1 NEMO â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20932475 21811235 21212807 16360037 21777808 16906147 14651848 18583959
NEMO FADD â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21458669 30561431 16227629
EGFR RABX5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28065597 16499958
JAK1 STAT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32123171 11722592 34521819 32953130 11294897 10982844 15322115 12637327 7690989 14978237 15284024 10918587 7543024 32814877 12817007 34950606 7657660 11839738
TRAF2 NEMO â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10980203 28249776 31502302 23007157 12867425
NEMO BIRC2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20932475 23732909 12867425 22990857 23524849 30561431
RIPK2 TRAF1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9705938 16713569
IKKB TRAF1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12709429 20856938
TRAF1 TNR1A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 8565075 19287455 16713569 7859281
EGFR TNR1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
TRAF1 UBB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 14743216 33961781
NEMO UBB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 14743216 33961781
TNR1A UBB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 14743216 33961781
JAK2 STAT1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11294897 15322115 11152457 12637327 7690989 20353823 19834108 14978237 15284024 10918587 24255956 7543024 12817007 7657660 11839738
SLMAP RABX5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24366813 33961781 24255178
FA40A SIKE1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 18782753 26496610
PHOCN SIKE1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 18782753 26496610 19156129
SIKE1 FGOP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 18782753 26496610
PHOCN FA40A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33633399 33961781 18782753 19156129
FA40A FGOP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 18782753 26496610
EGFR STAT1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
BIRC2 TRAF2 â—¼   UBIQUITINATION ✅ - 0.87 0.87 Signor 20651737
JAK2 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24240702 9363897 10635327 16273093 23838182 10358079
JAK1 GRB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11527382 8536716
GRB2 HSP7C â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19380743 31980649 12577067 33957083
TNFA RIPK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34315543 31898971 16603398 33469115 32968279 21620750 30420664 27560715 27458237 22028622 25911380 27545878 21331077 24726327 22099304 12887920 20005846 32599618 27307491 24980434 23955153 23104095 12753742 22675546 26670046 23032187
TP4AP TRAF2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16876162 16189514 16713569 14585990
TNR1A JAK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11801527 9510175
TNR1A JAK2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18606683 9510175
TNFA TRADD â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15485837 22099304 23732909 12887920 20005846 27545878 27307491 27458237 24980434 16603398 23955153 32968279 21822306 30561431 12753742
TRADD TRAF1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8565075 19287455 16713569
TNFA BIRC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25911380 12887920 20005846 27307491 32968279 21822306 30561431
BIRC3 RIPK2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9705938 19464198 21931591
RIPK2 NEMO â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18079694 16189514 10880512
UBC9 TNR1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 16713569 9563508
CASPA TNFL6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15659383 16498403 12198154
CASPA TNR1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11098060 9045686 15659383
BIRC2 TRAF1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
JAK2 STAT1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
EGFR NEMO â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
SUMO1 TNR1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10187798 8906799 16189514
RIPK1 FADD â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11854271 23972990 24098568 33469115 11002422 26733177 19524513 26865630 32296183 22864571 27560715 23744296 32024820 21183682 30561431 21052097 19373245 24577083 21458669 21737329 32707033 21525013 22848449 29497034 33961781 26186194 26972597 21620750
BIRC2 RIPK1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
TRADD RIPK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8612133 24735611 27768232 21724995 16603398 30561431 23429285
RIPK1 BIRC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26612615 21931591 27197231 29021293 19854138 23972990 18570872 30561431 21113135 29955050
RIPK1 TRAF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 8612133 25416956 16713569 19287455
RIPK1 BIRC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21931591 23972990 33526051 18570872 21113135 16547522
RIPK2 TRAF2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9705938 16189514 16713569 32707033 21903422
TRAF2 TNFA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15485837 25911380 12887920 20005846 27545878 27307491 24980434 16603398 23955153 32968279 21822306 30420664 30561431
TNR1A BIRC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18022363 19815541 30561431 8943045 32968279 30420664 25681446
RIPK2 BIRC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9705938 19464198 16189514 21931591 9642260 30026309
SIKE1 STRN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26496610 33961781 24255178 24366813 18782753
STRN FGOP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26496610 33961781 24255178 24366813 18782753
STRN3 SLMAP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26496610 33961781 24255178 24366813 18782753
STRN3 FGOP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26496610 33961781 24255178 24366813 18782753
FA40A STRN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 33961781 18782753
SIKE1 STRN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 18782753 26496610
SLMAP STRN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24366813 24255178 26344197
STRN4 PHOCN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18782753 26344197 19156129
PHOCN SLMAP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24255178 24366813 18782753 19156129
SIKE1 SLMAP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26496610 33961781 24255178 24366813 18782753
KC1E HSP7C â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 23455922 33961781
FAN TNR1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10187805 8808629 17599063
TP4AP TNR1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 20458742 14585990
BAG4 TNR1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9915703 11909948
TNR1A HSP7C â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14743216 16189514 11909948
TNR1A TNFB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 8288897 2170974 8387891 1310388 8182064
TNR1A IKKB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21331078 25241761 10755617 31406107 21724995 18949366 11002417 11821416 30420664
BAG4 HSP7C â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 29568061 11909948 25036637
EGFR TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 23972990 25402006 18271526
EGFR HSP7C â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 12471035 24189400 23956138 24658140 28065597 25402006 15657067
EGFR STAT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24797263 31980649 23956138 11294897 15322115 24658140 12637327 7690989 15284024 10918587 25402006 7543024 12070153 12817007 10358079 7657660 11839738
EGFR JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8524316 15284024
TNFL6 GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11741599 12023017 12220636 16713569
JAK2 GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7500025 17474147 8536716 8950973
JAK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8536716 11527382
PSMD2 TNR1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9126987 16189514 7601280
STAT1 SUMO1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10805787 12855578 18031232
FADD TNFL6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15659383 25241761 12887920 21803845 16498403 12753742 24025841
FADD CASPA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9045686 15659383 9228018 11717445 20829884 15069192
STAT1 JAK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12223098 21239533
RIPK1 TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25416956 24735611 23972990 16603398 8612133 32296183 16291755 11181075 19815541 24434549 30561431 21810480 11479302 31502302 27768232 20577214 25716317 21282461 25882049 8702708 9020361 16713569 29352166 23007157
RIPK1 NEMO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24735611 10755617 17702576 26740240 21606198 14653779 16603398 16543241 21113135 16547522 26865630 10980203 23746843 30561431 11262391 32024692 19373245 18029035 31502302 21458669 10880512 18212736 22099304 28249776 21383699 26802121 23104095 27929056
TRAF2 SIKE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10581243 12133833 19479062
TRAF1 TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10544141 25241761 20385093 14557256 21903422 14743216 32296183 29748372 11181075 15383523 8702708 8069916 19287455 16713569 9718306 25996949 9500555 33961781
IKKB TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32024699 20449947 21782231 16713569 25241761 27387502 19150425 23007157 11359906 18362886
TRAF2 TRADD â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 9020361 32296183 16713569 11479302 11181075 19815541 10892748 12796506 27768232 23955153 8702708 32968279 8565075 30561431 23429285 10911999
TRADD TNR1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22297296 11684708 21724995 8943045 9082980 24130170 32968279 8565075 30420664 7758105 16919273 19524513 8612133 24758719 9129204 29108854 8621670 10187805 27552911 18776134 19781631 9916731 11821416 9915703 15310755 23429285 16611992 11035039 18939944 19641494 11934887 23955153 33961781
TRADD BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8943045 12887920
BIRC2 TRAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 11907583 16713569 21988832 20447407 9384571 8943045 25996949 33961781 23524849 16891304 30561431 8548810 21903422
BIRC3 TRAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11907583 25241761 16713569 30948266 9384571 25996949 33961781 23524849
FA40A STRN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 33961781 24255178 24366813 18782753
PHOCN STRN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19156129 26496610 33961781 24255178 24366813 18782753 26344197
STRN STRN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 33961781 24255178 24366813 22939629 18782753
STRN SLMAP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 33961781 24255178 24366813 18782753 26344197
STRN STRN4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 33961781 24255178 24366813 18782753
PHOCN STRN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19156129 26496610 33961781 24255178 33633399 24366813 18782753 26344197
FA40A STRN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 33961781 24255178 33633399 24366813 18782753
SIKE1 STRN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 26496610 33961781 24255178 24366813 18782753
STRN3 STRN4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 22863883 33961781 24255178 24366813 18782753
FA40A SLMAP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33961781 24255178 24366813 18782753 26344197
PI42B TNR1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 9038203 16713569 9753329
TNFA TNR1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25241761 34315543 2848815 26670046 11448951 31898971 9568681 20103630 2170559 33469115 22801493 8182064 32968279 30420664 14743216 9488135 8288897 8805640 27560715 23746843 2170974 22028622 2158863 15173183 19084540 15485837 25911380 27545878 1310388 10634209 24726327 22099304 12887920 24070898 27307491 24980434 33815386 23955153 33961781 20080539 26186194 22675546 12753742 23032187
NEMO IKKB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23986494 20211142 16611882 20098747 15802604 30913450 16547522 14743216 18450452 10980203 19666608 23131831 21455180 16906147 15184390 24469399 19820708 18462684 31145594 15749833 28249776 24618592 10968790 19422324 30500824 23104095 16938294 31932854 18949366 20167598 16603398 25286246 18583959 24266532 22605335 27426725 26500060 19706536 19365808 18037881 20932476 30404796 16319058 9751060 23506214 25979343 17363973 25400026 22990857 12657630 30561431 12459277 12486103 16583354 29474632 32024699 11971985 11057907 18266467 12133833 24240172 18266324 23016877 21423167 17977820 33961781 20368414 32731169 28514442 25304104 18207244 12612076 19959994 25852190 21903422 29111346 26496610 19656241 17000764 21803029 16497931 20434986 16129692 17568778 11864612 22099304 19815509 17693255 27929056
BIRC3 TRAF2 â—¼   UBIQUITINATION ✅ - 0.9 0.9 Signor 18997794
UTP20 UTP6 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
TRAF2 RIPK1 â—¼   UP_REGULATES ✅ + 0.9 0.9 Signor 10795740
TRAF2 RIPK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18621737
HSP7C DPH1 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 33961781 29568061
BIRC2 TRAF2 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
RIPK1 TRAF2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
UTP15 UTP6 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
SLMAP FGOP2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 24366813 33961781 24255178 26496610
PSMD2 UBB â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
TRADD FADD â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 24686082 32296183 12107169 12796506 8681376 21724995 12911633 23955153 11112409 16919273 8565075 30561431 10911999
FADD TNR1A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16611992 15659383 11035039 9129204 8565075
RIPK1 TNR1A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 24098568 16115877 18949366 19773432 24130170 30420664 21113135 11002422 19524513 8612133 18450452 24758719 29431638 25388546 19815541 28388439 27591049 22817896 28817177 22733818 27552911 18022363 16968706 22179575 19781631 27321185 31406107 15258597 18621737 21737329 20825417 25681446 23429285 16611992 20448643 21331078 18724939 22848449 18939944 7538908 26802121 8985253 33961781
TRAF2 TNR1A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 25241761 24735611 8943045 32968279 8565075 30420664 8612133 28388439 19815541 29108854 30561431 18776134 22179575 18022363 27321185 31406107 11821416 26212014 16611992 20448643 16713569 20333651 15743837
EGFR GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19254954 7518560 31980649 9416834 7592693 23956138 14679214 10085134 7510700 27059931 21706016 25402006 16799092 16729043 8665853 15657067 24797263 12577067 8810325 7650032 11960376 23799367 25187647 8626525 10026169 19289468 18271526 21278786 7506413 17971399 8940013 20124286 11726515 9886492 10595738 24189400 9020117 19531499 20473329 9020193 8662998 8647858 1322798 8887653 10229072 16273093 25754235 31959764 11370743 16713569 21596750 9685397 24658140 31985874 22973453 11896612 20067773 17242169 19836242 8810340 21278788 30544639 7527043 9050991 11408594 8621459
TRAF2 BIRC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 25241761 10753917 21988832 19506082 9384571 8943045 19584093 16263936 21903422 32296183 11181075 19815541 20562859 8643514 15861135 16891304 16282325 30561431 8548810 30359437 11907583 20184394 21331077 25716317 25882049 23524849 27534557 25681446 21653699 16713569 20447407 23007157 20348096 33961781 24276241
TRAF2 BIRC3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 30948266 10753917 21988832 9384571 20385093 19815541 20562859 8643514 16891304 16282325 24464131 8548810 11907583 21331077 27534557 23524849 15310755 23543740 16713569 23007157 33961781
BIRC3 TRAF1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
TRADD TRAF2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
BIRC3 TRAF2 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
TRAF1 TRAF2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
UBC9 SUMO1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16189514 21518904 22411991 25416956 21949651 17956732 32296183 18691969 16732283 18211895 10961991 21212807 9497385 26496610 24352468 11735126 19684601 17491593 14673145 26264872 9920803 17353931 19785004 23871147 9353268 17938407 16524884 26344197 12924945 16494873 8921390 16713569 18264111 21174150 15931224 25502805 18359863 20501649
STRN STRN3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN STRN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN3 STRN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SIKE1 STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SLMAP STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SLMAP STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SIKE1 STRN4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
FADD RIPK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SIKE1 SLMAP â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SIKE1 STRN3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ATR CDC6 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDC6 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDC6 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
RIPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11116146
JAK2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17389395 10635327 17081983 10358079 16273093 16799092 18691976 10459005 9363897 15284024 23838182 17016520 18669648 15302935
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 23956138 12070153 11839738 10918587 11447289 11997436 14967450 25402006 12040186 24797263 15173823 7543024 15322115 10358079 6321473 11294897 7690989 10982844 19568798 12637327 14585353 15199124 17496910 11438544 10748192 24658140 7657660 12817007 31980649 22693070 9355737 19615955 11152457 15284024 15567848 7592750 16488589
JAK2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8536716 8950973 7500025 17474147 19273609
RIPK1 FADD â—¼   PHYSICAL_INTERACTION 90.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 14744430 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18545270 18633355 18641653 19392652 19411070 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22421439 22427918 22955274 23010170 23069999 23073834 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24366341 24378531 24699077 24958845 26024392 26201938 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 8910423 9184224 9217161 9488730 9759866
TRAF2 FADD â—¼   PHYSICAL_INTERACTION 74.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22427918 22955274 23010170 23069999 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 8910423 9488730 9759866
FADD TRADD â—¼   PHYSICAL_INTERACTION 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
RIPK1 FADD â—¼   SHARES_COMPLEX 90.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 14744430 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18545270 18633355 18641653 19392652 19411070 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22421439 22427918 22955274 23010170 23069999 23073834 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24366341 24378531 24699077 24958845 26024392 26201938 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 8910423 9184224 9217161 9488730 9759866
TRAF2 FADD â—¼   SHARES_COMPLEX 74.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22427918 22955274 23010170 23069999 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 8910423 9488730 9759866
FADD TRADD â—¼   SHARES_COMPLEX 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 FADD â—¼   ENZYMATIC_REACTION ✅ 74.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22427918 22955274 23010170 23069999 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 8910423 9488730 9759866
STAT1 FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10848577
TRADD FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 8565075 14744432 12911633 21760970 9430228 21724995 21741934 12796506 10911999 20203691 23955153 32296183 12107169 11112409 11464215 8681376 12887920 24686082 21183682 18545270
FADD RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 16585540 22864571 26733177 11002422 11854271 19524512 21458669 21525013 21052097 26865630 21741934 23972990 21620750 26186194 27560715 24098568 20203691 16227629 32296183 18485876 32024820 22890322 11464215 21737329 12887920 21183682 19524513 26972597 19373245 22848449 24577083
JAK1 STAT1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10426994 11907067 12244150 12811837 15536084 16081783 16713974 16785506 19833085 20856220 21840487 23124025 24751819 7512720 7521688
JAK2 STAT1 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
STAT1 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
JAK2 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 81.0 1.0 Omnipath 11839738 10918587 7888666 20353823 7543024 15322115 25950470 23331499 21071413 14978237 11294897 7690989 7504785 18988627 12637327 25535282 11438544 21576360 10748192 7657660 12817007 14984365 7504784 21207025 9355737 11152457 7615558 19834108 15284024 10982844 7592750 19787091
JAK1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 132.0 1.0 Omnipath 35317858 11839738 10918587 15261459 34950606 11306517 8756628 12244150 8156998 9535918 10748192 7657660 12817007 23257612 27774606 25297818 22306691 8631301 7510216 14963018 15284024 24243840 7592750 10851062 11823427 23331499 7532278 11418623 11722592 18988627 12637327 27387064 8662591 10022928 19088846 32953130 7796299 7504784 23124025 19787091 24058793 20169197 7543024 15322115 18941194 19534553 15978943 14978237 11294897 14764663 21429244 14565860 34228987 25386349 18989459 34521819 9020188 19535621 10982844 21576360 12759422 18508557 8232552 12093291 12040185 20006573 8662795 7690989 20087684 11438544 20035788 11972023 29145629 9355737 11152457 12517932 18389480
TRAF2 RIPK1 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 TRADD â—¼   PHYSICAL_INTERACTION 78.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 12887920 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 16713974 17301840 17462996 17496911 17560373 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19632174 19641494 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 8974401 9379049 9488730 9582321
TRAF2 RIPK1 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 TRADD â—¼   SHARES_COMPLEX 78.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 12887920 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 16713974 17301840 17462996 17496911 17560373 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19632174 19641494 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 8974401 9379049 9488730 9582321
TRAF2 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 TRADD â—¼   ENZYMATIC_REACTION ✅ 78.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 12887920 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 16713974 17301840 17462996 17496911 17560373 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19632174 19641494 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 8974401 9379049 9488730 9582321
BIRC2 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12887920 18570872 20547836 15147886 21931591 16603398 19284370 18621737
TRADD RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12887920 24735611 20203691 21724995 8612133 21741934 16603398 21119000
BIRC3 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18570872 33526051 15147886 21931591 16603398 19284370 18621737
TRAF2 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 8702708 8612133 25416956 16713569 18621737 25882049 16291755 18981220 21741934 21232017 20577214 11181075 10795740 23972990 21119000 15175328 20203691 21810480 21282461 9712898 32296183 23007157 25716317 20448643 12887920 24735611 15258597 24434549 19815541 16603398 11479302 9020361
TRAF2 TRADD â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10465784 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15592525 15699106 16713974 17301840 17462996 17496911 17916596 18264787 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 9379049 9488730 9582321
TRAF2 TRAF1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 TRADD â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10465784 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15592525 15699106 16713974 17301840 17462996 17496911 17916596 18264787 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 9379049 9488730 9582321
TRAF2 TRAF1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 TRAF1 â—¼   ENZYMATIC_REACTION ✅ 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF1 TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8702708 15383523 16713569 8069916 21903422 25996949 9500555 14743216 11181075 15323523 25241761 14557256 20385093 32296183 10544141 12887920 19287455 8548810 9718306 31515488 29748372
TRADD TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 8702708 8565075 14585074 16713569 27383048 18621737 14743216 12796506 21741934 11181075 21119000 10911999 20203691 10892748 23955153 11112773 18439848 32296183 15485837 12887920 12517920 19815541 11479302 9020361
TRAF2 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 18997792 8643514 11907583 16713569 18621737 18997794 21988832 18606850 9384571 16891304 10753917 18981220 24464131 20562859 25241761 23543740 20385093 21331077 23007157 16282325 23524849 8548810 19815541
TRAF2 TRAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8702708 15383523 16713569 8069916 21903422 25996949 9500555 14743216 11181075 15323523 25241761 14557256 20385093 32296183 10544141 12887920 19287455 8548810 9718306 31515488 29748372
TRAF2 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 21653699 25681446 8943045 8643514 11907583 16713569 20184394 18621737 18997794 21988832 25882049 9384571 21903422 16891304 10753917 20447407 18981220 16189514 15861135 11181075 20348096 20562859 25241761 19584093 32296183 21331077 23007157 16282325 19506082 25716317 23524849 24276241 16263936 12887920 8548810 19815541
TRAF2 RIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16713569 9705938 21903422
JAK1 JAK2 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
JAK1 JAK2 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
BIRC3 TRADD â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 35941131 22179575 22848449 23313255 24098568 34876703 16282325 20385093 22435550 18178551 19910467
BIRC2 TRADD â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 35941131 22179575 22848449 23313255 24098568 34876703 16282325 20385093 22435550 18178551 19910467
TRADD TRAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8565075 12887920 19287455 10629108 18439848 16713569
BIRC2 RIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19464198 16189514 21931591 9642260