Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ATF2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11243868 19948881
JUN BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16229810 17434164
PIAS4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21113239
HIPK2 SUMO1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 5217735 15896780
PARP1 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
SUMO3 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19622798
SUMO1 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19622798
SUMO1 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SUMO2 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
PIAS4 UBE2K â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
PIAS4 SUMO3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
PIAS4 ZHX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
SUMO1 PML â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17036045 5219211
PML JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671405 10620019
SUMO2 RAD51 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19956565 1000252
SUMO1 RAD51 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19956565 1000252
ETS1 RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16398215
TRPS1 RNF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12885770 5216574
RNF4 TRPS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12885770
SUMO1 SP100 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SP100 ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15247905
ELK1 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17036045 5219211
HDAC4 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12032081 18691969
SUMO1 KCNK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 20498050 1004712107
SUMO1 KCNK1 â—¼   PROXIMITY 2.0 0.8 intact 20498050 1004712107
RCC1 RAN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7878053 1944575
SMAD4 DACH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14525983
SMAD4 PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PIAS1 PPARG â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16127449 20711444
PIAS1 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUMO3 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11451954 17938407
H4 PARP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 30804502 27248496 33961781 19470756 20525793
PIAS4 UBC9 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 22661230 12727872 20696768 21988832
SUMO1 TIF1B â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19596686 24654937 21098080 21642969 18082607
IKZF1 UBC9 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32296183 16189514 25416956 16713569 30217970
SUMO2 SAE2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19471022 32786267 16620772 25027693 21252943 21693764
P53 LMNA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 30419336 25144556 29568061
UBC9 ZN451 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16189514 26524493 16713569 18656483 20936779 21516116
UBC9 TIF1B â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31427381 21940674 26055329 24018422 18488044 18082607
TIF1B P53 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 20858735 17056014 32807901 20864041
RAD51 SUMO1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
SP100 SUMO1 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
BRCA1 H4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16628214 30804502
BRCA1 TIF1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
PIAS2 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19779455 34079125
PARP1 JUN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24636898 25609649
PARP1 TOP2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 16794079
ETS1 PIAS4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17456046 16862185
PML PPARG â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32929351 20211142
RNF4 DAXX â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 29695423
RNF4 HNRPK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29180619 32296183
SUMO1 MITF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22012259 16189514 16029420 10694430
SUMO1 ANDR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12177000 21242980
RAN T194A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
JUN P53 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31182485 25609649
JUN H4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25609649 30804502
DAXX ITF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19563778 20211142
SAE2 SUMO3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16189514 21518904 16620772 25027693 12924945
LMNA TIF1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22412018 25948554
T194A UBC9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TRI27 UBC9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19549727 20972456
B2MG UBC9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
H4 UBC9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14578449 30804502
ZHX1 UBC9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23686912 21988832
GOGA2 UBC9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25416956 29568061
UBC9 TRI55 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11927605 15802564
UBC9 TRIM3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 34508066
UBC9 TRI63 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11927605 16713569
T194A RBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
B2MG RBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
B2MG RAGP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
T194A RAGP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
B2MG T194A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
UBC9 HIPK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15958389 16713569 19549727 10535925 20936779 15896780 14609633
HIPK2 CBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11740489 16713569
UBC9 RNF4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29180619 19549727 32296183 20936779
TRPS1 SUMO1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17391059 23772552
UBC9 RAN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
SUMO2 ETV6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21693764 35140242 19471022 12626745
TRAF3 ETV6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 33961781 22792062
SMAD4 JUN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10220381 25609649
UBC9 PTEN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12620973 22713753
SUMO2 ZHX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21693764 16524884 19471022 21252943
LMNA PIAS2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 29568061 24623722
UBC9 RCC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
RCC1 RBP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HNRPK UBC9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 16189514 22825850 16713569
KCNK1 UBC9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15820677 20498050
TRPS1 UBC9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17391059 23772552
P63 UBC9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15539951 15611636
UBC9 TF7L2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23395904 21988832
SAE2 RBP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26261240 11792325
UBC9 ATF2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9488727 16713569
PARP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 25252691 26831064
BRCA1 UBC9 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19287951 20016594
HIPK2 PML â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
LMNA PARP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 30419336 22412018 25948554 29568061
ITF2 PIAS4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15831457 12727872 20211142
SUMO1 PIAS4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20016603 15831457 16524884
P63 DAXX â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15339933 12954772
UBC9 TRAF3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32296183 24260396
UBC9 UBE2K â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18691969 21139563 15723079 29773808 21098080 26344197
UBC9 AP2A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12072434 24835590
UBC9 TFE2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10497239
UBC9 ITF2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12727872 23395904 23772552
UBC9 SRBP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12615929 16713569
P53 ITF2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 25402006 25609649
TRI55 TRI63 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18157088 11243782 23414517
PIAS4 SUMO2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
SUMO1 UBE2K â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
JUN PML â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
SUMO2 BRCA1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20016603 20016594 22689573 21693764 21147198
SUMO2 PARP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19471022 21693764 32786267 25027693 21252943 19779455
RNF4 TIF1B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29180619 21252943 24907272
SUMO3 SP100 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16524884 17000644 25027693
SUMO1 HNRPK â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15161980 19596686 23092970
IPO13 RAN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23435562 17828378 21139563
UBC9 JUN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10788439 16713569 11877416 8733011
UBC9 PPARG â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26192107 15229330 19692572
PIAS1 ANDR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31752909 11877418 12177000 25552417 11117529
SUMO2 RBP2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19471022 16524884 32786267 16620772 25027693 21693764
LMNA UBC9 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19596686 16248985
UBE2K P53 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15280377 23933584 10634809 16713569
RCC1 H4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30021884 30804502 20347844
HNRPK P53 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23092970 25144556 32807901 21821029 34452628
TOP2B UBC9 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15561718 10862613
UBC9 MYB â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22910413 16713569 11779867 27150054
UBC9 AP2C â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12072434 24835590
HIPK2 P63 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11925430 16713569 21602882
SUMO1 PARP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23871147 15576338 19779455 15561718 19596686
PARP1 UBC9 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23871147 9197546 15561718 19596686
PIAS4 SUMO3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20016603 20696768 15383276 16713569
PIAS4 ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14981544 11439351 16713569
SUMO1 SUMO3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24654937 25027693 15576338 17938407 21098080
SUMO1 SRBP2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12615929 18403372
RAN H4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 30804502 30021884
SUMO2 SAE1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19471022 32786267 26496610 16620772 25027693
SUMO2 TOP2B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19471022 19394292 25027693 21252943 21693764
SAE1 SUMO3 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
PARP1 PIAS4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19779455 20696768
PIAS4 SUMO2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19471022 15383276 16713569 19394292 16524884 32786267 20016603 20696768 21252943 22578841 21693764
SUMO2 PML â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17000644 16189514 23543742 28851805 19553342 21148299 22155184 24190887 20826694 21779164 22578841 17081986 21693764 24637324 15940266 20797634 9452416 19471022 16713569 25027693 21252943
SUMO1 RAD51 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24046452 9891849 8812453 19956565 10666456
SUMO2 SP100 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17000644 32296183 19471022 21988832 16524884 25027693 21252943 21693764 17491593
PIAS1 SUMO1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27032383 24654937 19217413 15561718 22578841 16524884 11583632 14609633 18806873
ELK1 SUMO1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23395904 12887893 20811994 19684601 17036045
DACH1 JUN â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17182846 25609649 16980615
PTEN P53 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12620407 16713569 18339852 24141722 14559824
DAXX TF7L2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16569639 19563778
PPARG HDAC4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12943985 21605119
ETS1 CBP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9528793 18443043 35140242 7774816 15572696
UBC9 PIAS2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32296183 16189514 25416956 16713569 11867732 21988832 19549727 16148010 12177000 25409927 20936779 14609633
PIAS2 P53 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25241761 11867732 19901969 19339993 18624398
SOX10 UBC9 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29295999 16494873
AP2C P53 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12226108 16713569
ITF2 TFE2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 20211142
BRCA1 UBE2K â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19712108 23246971 21965653 17873885
TF7L2 PARP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27684187 30833792 17283121
PIAS4 SMAD4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12815042 12740389 12904571
MYB PML â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15194430 20802522
CBP SUMO1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28630323 23395904 27129204
SUMO1 ETV6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24654937 26871637 12626745 11078523
UBC9 TOP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 10759568
P53 TOP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10468612 18697815 16713569 8639538 11805286 32807901
RAN ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 32814769 10400640
UBC9 SMAD4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29892012 16189514 16713569 15231748 21988832 15637079 12621041
SMAD4 ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12226080 16713569
JUN ETS1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20195357 8557686
CBP DAXX â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16287980 32545337 11799127
UBC9 ETS1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9333025 16189514 16713569
PIAS1 SUMO2 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
ANDR HDAC4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12943985 21242980
UBC9 ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8798622 19692572 10383460
ANDR ITF2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12799378 16713569
UBC9 DNM3B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11735126 16713569
UBC9 SRBP2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12615929 16713569 20936779
UBC9 M3K1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21336309 9563508
UBC9 TNR1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 16713569 9563508
UBC9 SALL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12200128 16713569
P53 TOP2B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10666337 16713569
PML RNF4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CBP BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10655477 11782371 16713569 16417649 9926942 12700228 16860316 9443979
ANDR BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11085509 16713569 11016951
BRCA1 SUMO1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26831064 18025037 20016594
UBC9 FMR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31413325 26496610 16713569 11367701
HIPK2 DAXX â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19465479 14678985 23536002
RNF4 PML â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29180619 19380586 24907272 15707587 23028697 18408734 21252943 18708055 24637324 22388745
UBC9 PML â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9885291 18691969 17081986 27030546 32001251 21988832 30292834 27903803 30935967 29773808 15809060 29535160 12641448 15561718 22155184 29599493
PML JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15626733 9671405 16916642 10620019
SUMO1 SP100 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11313457 16189514 25416956 32296183 16524884 21880768 24654937 15017387 24637324 10212234 17491593 9412458
ETS1 SP100 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15247905 16189514 11909962
RBP2 SUMO1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15161980 18359863 24654937 19785004 12192048 22578841 16524884 19596686
SUMO1 TNR6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8906799 9740801 16189514 11112409
SUMO1 TNR1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10187798 8906799 16189514
SUMO1 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 15144954 23543742 22214662 23604351 15017387 12917636 16732283 18583933 11867732 10961991 10562557 17369817 20972456 19246003 19684601 23825024 10788439 15242646 23150668 15327968 15576338 16122737 17060459 21316347 16713569 15931224 20861261 23772552 32807901 20534433
IPO13 UBC9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11447110 23435562 21139563
ETV6 UBC9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10377438 25416956 16713569
SUMO2 DAXX â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17081986 19471022 19394292 32786267 16475184 28851805 21252943 22578841 21693764 21383010
DAXX ETS1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15247905 16861237 10698492
PPARG CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15556564 22070604 17704298 10339548 16713569 19596656 35140242 11877444 30595551 17312272 10848596 10622252
ELK1 UBC9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12887893 17036045 23395904
PIAS1 UBC9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 11867732 16148010 12177000 19692572 25557546 30217970 12356736 20936779 19965618 15561718 22661230 11583632 14609633
SAE1 SUMO3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17353931 12924945 26344197
UBC9 HDAC4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18691969 16166628 11451954 23417673 17491593
SUMO2 PIAS2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19394292 16524884 32786267 21252943 22578841 21693764 19217413
SUMO2 RAGP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17000644 16189514 19471022 9556629 17099698 22194619 17099700 32786267 16620772 25027693 21252943 21693764 20797634
PIAS2 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11117529 16713569 12177000 9920921
UBC9 MITF â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 16029420 10694430
RCC1 RAGP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
UBC9 CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28630323 22227369 28680062 23395904
SRBP2 CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 16799563 8918891 25368385
WT1 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 8389468 10744705 9556563 25601757
DAXX SUMO2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CBP ATF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16303757 17296604 11564156 9786917 31964530 9659924
JUN ATF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8027667 20102225 28514442 16511568 23661758 15546613 26496610 2320002 20195357 10327051 1827203 9445037 20511396 10207054 25609649 33961781
JUN BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12080089 25609649 16713569
P53 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14710355 16713569 21742769 15571721 26140185 9926942 9582019 14636569 14978302 16677609 18501503 9482880 19509300 16969499 31073355
RAD51 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31270457 31009828 11498787 16713569 19766185 25659039 19369211 25499220 9774970 28319063 17302439 9008167 14636569 28976962 24085845 34408138 29656893
BRCA1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 9774970 9008167
SUMO1 HIPK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15958389 16253240 21145359 10535925 15896780 21192925 24637324 14609633
HIPK2 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16212962 25313037 16713569 17349959 11925430 34133717 11875057 11780126 15896780 11740489 22110707 21057547 25961923
P53 PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 9312059 23169665 15044383 12898523 14627987 9565608 32807901
TOP1 PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 34079125 15247263 15848144
ETS1 PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10435618 11973649 24448423
PARP1 PIAS4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19779455 20932475
CBP PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 12234245 17239008 10077561 10610177 25733689 12622724 12142048
P53 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 25241761 22869143 16713569 12915590 14976551 16007146 20972456 12006491 15375079 11025664 11704853 11080164 21057547
SUMO1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11948183 16189514 9885291 19015637 21305000 23028697 28851805 23604351 15017387 22155184 21057547 19380586 24190887 20826694 20972456 23830076 17027752 24654937 25497731 9756909 21779164 31879127 17081986 18625722 8806687 17081985 17344210 19217413 17036045 18474224 9452416 20188669 16501610 22406621 22875967 9427741 15561718 21098080 11080164 11160742
P53 RAD51 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8617246 16713569 16983346 26140185 12606585 11948396 16600179 14636569 9380510 12750285 11002423 15064730
SUMO1 RNF4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29180619 32296183 24907272 15707587 23086935 24151981 24844634
RNF4 SUMO2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26950370 23560854 32733036 32786267 23530056 23086935 22661230 25533185 29180619 20943951 31087003 24969970 32521226 29120074 29549242 18408734 21252943 24151981 24844634
UBC9 SP100 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18691969 28620180 20805487 20936779 32001251 18538659 17491593
SP100 ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15247905 16189514 11909962
PIAS2 SUMO1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 16189514 25416956 11867732 21988832 24654937 16524884 19217413 16204249 14609633 17036045
UBC9 BLMH â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 16189514 9855622
SMAD4 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
PIAS2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14514699
CBP JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 2138276 17296604 9786917 18443043 10327051 8028671 9659924 15994313 16055710
ANDR JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9211894 33640491 16713569 8798722
JUN ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1945412 8247540
UBC9 DAXX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17081986 18691969 15087395 16713569 23395904 12150977 21474068 11112409
ANDR DAXX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15572661 27671201 32694250 15350595
DAXX H4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12140263 21724829 19862764 27248496 25416818 33961781 24981860 23075851 29084956 32545337 23142979
WT1 ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20842112 18212735
ETS1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7848925 8999884
SUMO2 PIAS1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19471022 19394292 16524884 20016603 21252943 22578841 21693764 19217413 18806873
PIAS1 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15133049 25241761 16713569 11867732 11788578 20805487 11583632 10380882
PIAS1 DNM3A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20966256 22162396 14752048
SUMO2 SAE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11481243 19107418 11451954
UBC9 SAE1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17353931 15229330 26496610 33961781 19250909 12641448 26344197
DNM3A PIAS2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22162396 14752048 19786833
SRBP1 LMNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11929849 19727227 21993218 16713569
CBP ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12810069 16713569 9822653 20541699 33640491 9482849 15691881 34585037
SRBP1 CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16799563 8918891 10235267 9651391 9765204
TFE2 CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22387215 22207202 15507449 12435739 32098872
CBP H4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11163245 14720327 10097092 28680062 15005629 32238831 12665567 24361270 12566391
CBP MYB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16799563 11073948 23980173 35140242 12196545 14761981 16055500
CBP P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22084066 23908595 27618436 19234109 20962272 14759370 10551785 18485870 19166313 10473588 12426395 12154097 18753379 14722092 19357310 10848610 28630323 10648616 19880525 25314079 9194564 15632413 16537920 17434128 10196247 10823891 26976603 25451029 19220000 16713569 21390126 19805293 9288775 11782467
UBC9 FHIT â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11085938 16189514 16713569
UBC9 RBP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11709548 28514442 22194619 16713569 17353931 26261240 26496610 19785004 12192048 15931224 33961781 11792325 20936779 22464730 15608651
UBC9 DNM3A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22162396 16713569 14752048
UBC9 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 22214662 10380882 31467278 10961991 10562557 21829513 30217970 19684601 10788439 12565873 15327968 11853669 23202365 16122737 17060459 32780723 8921390 16713569 17709345 23772552 28784659 18624398 16442531
UBC9 SAE2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18691969 21518904 17643372 9920803 28165030 17353931 26496610 16455490 33961781 19250909 12641448 31575873 26344197
UBC9 WT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8798754 16189514 16713569
UBC9 RAGP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 21988832 29773808 20719936 18538659 18691969 16732283 21139563 9497385 26496610 14578449 18706886 16820290 22194619 29127148 17353931 11853669 16194093 12924945 17036045 28695742 32780723 31575873 16713569 23395904 19549727 15931224 33961781 21098080 20501649
P53 AP2A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12226108 16189514 16713569 16288208
DNM3B DNM3A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14752048 12867029 33961781 20923784 32968275 12145218
WT1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7559553
RAGP1 RBP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11709548 22194619 21518904 11854305 9019411 12192048 22464730 16204249 26344197
RNF4 SUMO1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TOP1 TOP2B â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
PIAS4 P53 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 11388671 15383276 16713569
P63 P53 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 16713569 25417702 19345189 11238924 23687300 21741598 24554706 22575646
PIAS1 SUMO1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
RNF4 SUMO2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
DAXX PML â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
PIAS2 SUMO2 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
SUMO1 JUN â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 10788439 15469925 11867732
HIPK2 MYB â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 15082531 16055500
UBC9 RAD51 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 8610150 16713569 8921390 24046452
SUMO1 TOP1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 12149243 12439742 11709553 24654937 15576338 19596686
DACH1 UBC9 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 16189514 16713569 11025202
UBC9 TNR6 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 8940097 16189514 16713569 9257699
IPO13 RAN â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
RNF4 ANDR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11719514 9710597 10617653 16713569
SUMO1 SAE1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9920803 20164921 15660128 19246003 12941704 12924945
RAGP1 RAN â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 16189514 9219684 20805321 10394366 7744835 33961781 8146159
UBC9 SUMO2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 16189514 32786267 16620772 21949651 26496610 31056421 22578841 17491593 30201799 23871147 24969970 30574775 11451954 17938407 16524884 21693764 12924945 20797634 19471022 16713569 33961781 25027693 28784659 26344197
SAE1 SUMO2 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
DAXX PML â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 30292834 21482821 21474068 10669754 14517282 12529400 20972456 15350595 10545115 21779164 11244500 32545337 17081986 12595526 15710327 21840486 17419608 12150977 24637324 10684855 17360386 10525530 23222847
RAGP1 SUMO1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17000644 16189514 17099698 17060450 17099700 24819975 9442102 16732283 9497385 24654937 19246003 18706886 22578841 16820290 16428860 22194619 9920803 22751501 15576338 24637324 16194093 12924945 17036045 20797634 15161980 23395904 18093978 9019411 15931224 20414307 9658103 20501649
SUMO1 DAXX â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11948183 17081986 23395904 18583933 30958586 16475184 12150977 20972456 20927612 25409927 21816224 28851805 21474068 11112409 22578841 31879127 19465479 21383010
SUMO1 SAE2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32296183 16189514 21518904 14673145 25416956 9920803 20164921 10217437 19246003 12924945 20501649
SUMO1 TOP2B â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21110914 15161980 15561718 10862613 19596686
RBP2 RAN â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10318915 28514442 11470507 21988832 24855949 10078529 33961781 26344197 7603572 20547757
RAN RCC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 7882974 12194828 31467278 10827954 1961752 18617507 11336674 20565941 7988569 10811801 22939629 10369786 29997244 7891706 33961781 26186194 26344197
DAXX TNR6 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 11773067 11193028 11003656 9990010 14637155 11483955 20565132 9215629 11495919
UBC9 SUMO3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 21518904 16713569 17353931 16524884 16620772 25027693 11451954 33961781 21949651 12924945 26344197
PML SUMO1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DAXX SUMO1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PIAS2 SUMO1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
SAE1 SUMO1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ATF2 JUN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
UBC9 SUMO1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16189514 21518904 22411991 25416956 21949651 17956732 32296183 18691969 16732283 18211895 10961991 21212807 9497385 26496610 24352468 11735126 19684601 17491593 14673145 26264872 9920803 17353931 19785004 23871147 9353268 17938407 16524884 26344197 12924945 16494873 8921390 16713569 18264111 21174150 15931224 25502805 18359863 20501649
DAXX P53 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 25241761 16713569 14557665 12954772 15364927 16845383 32545337 21482821 23038753 27626385 28875283 12482984 15339933 21134643
SAE1 SAE2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 16189514 22939629 26264872 9920803 17353931 20164921 26496610 10217437 22863883 15660128 33961781 10187858 12941704 26344197
RAN RCC1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ATF2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10366004 10327051 8530413 12052888 15068801 12751796 9502786 9141200 9252389 11238729 12903123 19255142 11736649 16511568 9819389
SMAD4 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10085140
ATF2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 25609649 20102225 15546613 2320002 10327051 1827203 9445037 26496610 20195357 16511568 20511396 10207054 8027667 23661758 31515488 18641343 1828107
BRCA1 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 PARP1 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 SUMO3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20016603 25218447 20016594 21147198
BRCA1 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 PARP1 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
SUMO1 HIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21145359 15896780 10535925 14609633
HIPK2 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17081983 27689990 27308327 26539288 19015637
HIPK2 DAXX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 19465479 14678985
PARP1 SUMO3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19779455 25218447 23750026 24782567
PARP1 TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 20875401 15911331 15848144 14699148 15247263
PIAS4 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 12815042 12740389 12904571
SUMO1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 22875967 9756909 25497731 17036045 21057547 18931695 19217413 8806687 16189514 17081985 11080164 11948183 9885291 19380586 17344210
RNF4 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23028697 18708055 15707587 24907272 18408734 21252943 22388745 24637324 19380586
PTEN RAD51 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10753747 11747822 12040186 15721744 16288286 16982858 17218252 17218262 18716620 19847259 22179046 22465479 23732914 24254977 25364523
TOP1 SUMO1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12149243 11709553 25114211 10759568
SUMO1 SAE1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 9920803 20164921 19107418 10187858 11481243 20501649
PIAS1 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16524884 22578841 19217413 18806873 14609633 11583632
PIAS2 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16204249 21988832 25416956 19217413 16189514 14609633 16524884 12764129
SUMO1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14514699 23331499 21071413 12813045 12740389
RCC1 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 26186194 10827954 11336674 18617507 10811801 29997244 31467278 16189514 7988569 10369786 20565941 1961752
SMAD4 ETS1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
SMAD4 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21836474 21926264 16580992 12524424
PIAS1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 14514699 21988832 23331499 15028714 15231748
JUN SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10220381 9312063 9732876
PPARG PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18065496 16775433 16425225 23867870 20198337 11378386
JUN MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1527086 8670250 12475180
JUN ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8557686 20195357
SOX10 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10973953 10982026 15760336 10938265 16494873 19026785 10942418 16921166
SOX10 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10973953 10982026 10942418 10938265