Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PIAS4 ZHX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
ATF2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11243868 19948881
JUN BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16229810 17434164
PIAS4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21113239
SMAD4 DACH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14525983
SP100 ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15247905
ETS1 RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16398215
HDAC4 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12032081 18691969
HIPK2 SUMO1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 5217735 15896780
PML JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671405 10620019
SUMO1 KCNK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 20498050 1004712107
SUMO1 KCNK1 â—¼   PROXIMITY 2.0 0.8 intact 20498050 1004712107
PIAS1 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PARP1 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
SUMO1 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19622798
SUMO3 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19622798
SMAD4 PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PIAS1 PPARG â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16127449 20711444
SUMO2 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
PIAS4 UBE2K â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
SUMO2 RAD51 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19956565 1000252
RCC1 RAN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7878053 1944575
TRPS1 RNF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12885770 5216574
RNF4 TRPS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12885770
SUMO3 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11451954 17938407
IKZF1 UBC9 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 32296183 30217970 16713569 25416956 16189514
PIAS4 UBC9 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 22661230 12727872 21988832 20696768
UBC9 ZN451 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 26524493 20936779 21516116 16713569 18656483 16189514
UBC9 TIF1B â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 18082607 21940674 31427381 18488044 24018422 26055329
TIF1B P53 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 20858735 17056014 32807901 20864041
P53 LMNA â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 29568061 30419336 25144556
SUMO1 TIF1B â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24654937 18082607 21642969 21098080 19596686
H4 PARP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 19470756 33961781 20525793 27248496 30804502
SUMO2 SAE2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 19471022 25027693 32786267 21252943 16620772 21693764
RAD51 SUMO1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
SP100 SUMO1 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
ZHX1 UBC9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21988832 23686912
RNF4 HNRPK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 29180619
SUMO1 ANDR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12177000 21242980
GOGA2 UBC9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 25416956
TRI27 UBC9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19549727 20972456
B2MG UBC9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
H4 UBC9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 14578449 30804502
T194A UBC9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
UBC9 TRI63 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11927605 16713569
UBC9 TRIM3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 34508066
UBC9 TRI55 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11927605 15802564
JUN P53 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 31182485
LMNA TIF1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25948554 22412018
BRCA1 TIF1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
JUN H4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 30804502
BRCA1 H4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16628214 30804502
DAXX ITF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20211142 19563778
T194A RAGP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
B2MG RAGP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SAE2 SUMO3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21518904 25027693 12924945 16189514 16620772
B2MG RBP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
B2MG T194A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
T194A RBP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAN T194A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RNF4 DAXX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 29695423
ETS1 PIAS4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17456046 16862185
PARP1 JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 24636898
SUMO1 MITF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22012259 16189514 16029420 10694430
PIAS2 PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19779455 34079125
PARP1 TOP2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16794079 34079125
PML PPARG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20211142 32929351
SUMO2 ZHX1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19471022 21252943 16524884 21693764
HNRPK UBC9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22825850 32296183 16189514 16713569
HIPK2 CBP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11740489 16713569
KCNK1 UBC9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20498050 15820677
P63 UBC9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15611636 15539951
TRPS1 UBC9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23772552 17391059
UBC9 RNF4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19549727 20936779 32296183 29180619
UBC9 RCC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
UBC9 HIPK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 14609633 10535925 19549727 20936779 16713569 15958389 15896780
UBC9 TF7L2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23395904 21988832
UBC9 RAN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
UBC9 PTEN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22713753 12620973
SAE2 RBP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11792325 26261240
TRAF3 ETV6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 22792062 35140242
SUMO2 ETV6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12626745 19471022 35140242 21693764
SMAD4 JUN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25609649 10220381
LMNA PIAS2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29568061 24623722 34079125
RCC1 RBP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TRPS1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23772552 17391059
HIPK2 PML â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
BRCA1 UBC9 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19287951 20016594
UBC9 ATF2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9488727 16713569
UBC9 ITF2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12727872 23772552 23395904
UBC9 TRAF3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24260396 32296183
UBC9 UBE2K â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21139563 26344197 29773808 21098080 18691969 15723079
UBC9 AP2A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12072434 24835590
UBC9 SRBP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12615929 16713569
UBC9 TFE2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10497239
P53 ITF2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25609649 25402006
TRI55 TRI63 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23414517 11243782 18157088
P63 DAXX â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12954772 15339933
ITF2 PIAS4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12727872 15831457 20211142
PARP1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 34079125 26831064 25252691
LMNA PARP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29568061 25948554 30419336 22412018
SUMO1 PIAS4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20016603 15831457 16524884
PIAS4 SUMO2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
SUMO1 UBE2K â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
JUN PML â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
SUMO1 HNRPK â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15161980 23092970 19596686
HNRPK P53 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 34452628 21821029 25144556 23092970 32807901
PIAS1 ANDR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11117529 31752909 25552417 11877418 12177000
TOP2B UBC9 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15561718 10862613
LMNA UBC9 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19596686 16248985
UBC9 JUN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8733011 11877416 16713569 10788439
UBC9 PPARG â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19692572 15229330 26192107
UBC9 AP2C â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12072434 24835590
UBC9 MYB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22910413 27150054 11779867 16713569
UBE2K P53 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23933584 10634809 16713569 15280377
RNF4 TIF1B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24907272 29180619 21252943
RCC1 H4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 30804502 20347844 30021884
SUMO2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21147198 20016594 20016603 22689573 21693764
SUMO2 PARP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19471022 25027693 32786267 19779455 21252943 21693764
SUMO2 RBP2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19471022 25027693 32786267 16524884 16620772 21693764
SUMO3 SP100 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17000644 25027693 16524884
PIAS4 ANDR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14981544 11439351 16713569
PARP1 UBC9 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15561718 23871147 9197546 19596686
SUMO1 SRBP2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18403372 12615929
HIPK2 P63 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11925430 21602882 16713569
RAN H4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 30804502 30021884
SUMO1 PARP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19779455 15561718 23871147 15576338 19596686
PIAS4 SUMO3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20016603 15383276 16713569 20696768
SUMO2 SAE1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19471022 25027693 32786267 26496610 16620772
SUMO1 SUMO3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 25027693 17938407 21098080 15576338
SUMO2 TOP2B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19471022 25027693 19394292 21252943 21693764
SAE1 SUMO3 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
ETS1 CBP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18443043 35140242 9528793 15572696 7774816
SOX10 UBC9 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16494873 29295999
UBC9 PIAS2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11867732 32296183 14609633 19549727 20936779 12177000 21988832 16713569 25409927 25416956 16189514 16148010
DAXX TF7L2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16569639 19563778
PTEN P53 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24141722 12620407 16713569 14559824 18339852
AP2C P53 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12226108 16713569
PIAS2 P53 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11867732 18624398 25241761 19339993 19901969
ITF2 TFE2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 20211142
DACH1 JUN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16980615 17182846 25609649
PPARG HDAC4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21605119 12943985
PARP1 PIAS4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19779455 20696768
SUMO2 PML â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25027693 21148299 23543742 17000644 20797634 22155184 21779164 19553342 9452416 17081986 16713569 24637324 21693764 19471022 21252943 15940266 16189514 22578841 20826694 24190887 28851805
SUMO1 RAD51 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24046452 10666456 19956565 9891849 8812453
SUMO2 SP100 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19471022 25027693 32296183 16524884 21252943 21988832 17000644 17491593 21693764
PIAS1 SUMO2 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
RAN ANDR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10400640 16713569 32814769
SMAD4 ANDR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12226080 16713569
UBC9 ANDR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19692572 8798622 10383460
ANDR HDAC4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21242980 12943985
ANDR ITF2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16713569 12799378
CBP DAXX â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16287980 11799127 32545337
CBP SUMO1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23395904 28630323 27129204
UBC9 DNM3B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11735126 16713569
UBC9 M3K1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9563508 21336309
UBC9 TNR1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9563508 16189514 16713569
UBC9 SALL1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16713569 12200128
UBC9 SRBP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20936779 12615929 16713569
UBC9 SMAD4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15637079 15231748 12621041 21988832 16713569 29892012 16189514
UBC9 ETS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9333025 16189514 16713569
UBC9 TOP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10759568 16713569
TF7L2 PARP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 30833792 27684187 17283121
P53 TOP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8639538 11805286 16713569 10468612 18697815 32807901
P53 TOP2B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10666337 16713569
JUN ETS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8557686 20195357
SUMO1 ETV6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24654937 12626745 26871637 11078523
MYB PML â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20802522 15194430
PIAS4 SMAD4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12740389 12815042 12904571
PML RNF4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
PIAS2 ANDR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9920921 16713569 11117529 12177000
ANDR BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11085509 11016951 16713569
SRBP2 CBP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16799563 25368385 8918891 16713569
PPARG CBP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17312272 15556564 35140242 19596656 17704298 22070604 30595551 10339548 16713569 10848596 11877444 10622252
UBC9 CBP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22227369 28680062 23395904 28630323
CBP BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10655477 9443979 9926942 12700228 16713569 16860316 11782371 16417649
ELK1 UBC9 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12887893 23395904 17036045
ETV6 UBC9 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25416956 16713569 10377438
PIAS1 UBC9 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12356736 11867732 22661230 14609633 19965618 19692572 11583632 20936779 15561718 30217970 12177000 16713569 25557546 16148010
IPO13 UBC9 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21139563 11447110 23435562
UBC9 HDAC4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11451954 23417673 16166628 18691969 17491593
UBC9 MITF â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 16029420 10694430
UBC9 PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30935967 32001251 12641448 9885291 15809060 29535160 17081986 27030546 29773808 27903803 15561718 18691969 30292834 21988832 29599493 22155184
UBC9 FMR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11367701 26496610 16713569 31413325
SUMO1 P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16732283 23150668 15017387 10961991 18583933 21316347 15327968 23825024 17369817 23543742 15931224 16713569 19684601 15144954 11867732 23604351 12917636 17060459 15576338 15242646 19246003 23772552 16189514 20534433 22214662 20972456 10562557 10788439 16122737 20861261 32807901
WT1 P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8389468 10744705 9556563 16713569 25601757 16189514
SUMO1 TNR1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10187798 8906799 16189514
RCC1 RAGP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194
SUMO2 RAGP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19471022 9556629 25027693 22194619 32786267 17099698 21252943 17099700 17000644 16189514 20797634 16620772 21693764
SUMO1 TNR6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8906799 11112409 16189514 9740801
BRCA1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26831064 18025037 20016594
HIPK2 DAXX â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23536002 19465479 14678985
SUMO2 DAXX â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22578841 19471022 19394292 32786267 16475184 17081986 21252943 21693764 28851805 21383010
DAXX ETS1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15247905 16861237 10698492
ETS1 SP100 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15247905 16189514 11909962
PML JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10620019 16916642 9671405 15626733
SUMO2 PIAS2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22578841 19394292 32786267 16524884 21252943 19217413 21693764
RNF4 PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18708055 29180619 24907272 19380586 18408734 15707587 21252943 22388745 24637324 23028697
RBP2 SUMO1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24654937 15161980 18359863 12192048 22578841 16524884 19785004 19596686
SUMO1 SP100 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24654937 11313457 32296183 15017387 10212234 24637324 16524884 9412458 25416956 21880768 16189514 17491593
DAXX SUMO2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CBP ANDR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34585037 15691881 33640491 20541699 16713569 9822653 9482849 12810069
ANDR DAXX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27671201 15350595 32694250 15572661
ANDR JUN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9211894 33640491 8798722 16713569
TFE2 CBP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22207202 22387215 12435739 32098872 15507449
SRBP1 CBP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8918891 9651391 16799563 9765204 10235267
CBP ATF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16303757 31964530 11564156 17296604 9786917 9659924
CBP MYB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12196545 35140242 11073948 23980173 16799563 14761981 16055500
CBP P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9288775 10848610 19234109 28630323 16537920 10551785 27618436 9194564 10648616 16713569 20962272 19880525 19220000 14722092 10196247 10473588 25451029 12154097 17434128 19357310 12426395 19805293 10823891 22084066 25314079 19166313 15632413 18485870 11782467 18753379 14759370 26976603 23908595 21390126
CBP JUN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18443043 8028671 16055710 2138276 10327051 15994313 16713569 17296604 9786917 9659924
CBP H4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 32238831 11163245 15005629 12665567 24361270 14720327 28680062 12566391 10097092
CBP PML â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17239008 25733689 12234245 12142048 10077561 12622724 16713569 10610177
UBC9 DAXX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12150977 21474068 11112409 17081986 18691969 16713569 23395904 15087395
UBC9 SP100 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28620180 20936779 18691969 20805487 18538659 32001251 17491593
UBC9 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10961991 15327968 16713569 19684601 23202365 31467278 17709345 8921390 30217970 17060459 23772552 16189514 11853669 18624398 22214662 16442531 10562557 21829513 32780723 10788439 12565873 16122737 10380882 28784659
UBC9 BLMH â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9855622 16189514 16713569
UBC9 RBP2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11709548 33961781 15931224 12192048 26261240 17353931 22194619 26496610 19785004 20936779 15608651 16713569 28514442 11792325 22464730
UBC9 SAE2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21518904 33961781 26344197 12641448 17353931 16455490 19250909 26496610 9920803 18691969 28165030 31575873 17643372 28514442
UBC9 FHIT â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11085938 16713569 16189514
UBC9 SAE1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 26344197 12641448 17353931 19250909 26496610 15229330 28514442
UBC9 WT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8798754 16189514 16713569
UBC9 DNM3A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14752048 16713569 22162396
UBC9 RAGP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16732283 33961781 28695742 26496610 20719936 16194093 31575873 14578449 21139563 15931224 9497385 29127148 29773808 21098080 19549727 18691969 16713569 16820290 17353931 21988832 12924945 18538659 20501649 28514442 23395904 16189514 11853669 18706886 22194619 32780723 17036045
PIAS1 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11867732 11583632 25241761 15133049 20805487 16713569 11788578 10380882
HIPK2 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16212962 25961923 21057547 11875057 17349959 11925430 34133717 11780126 11740489 16713569 22110707 15896780 25313037
P53 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14978302 9582019 14710355 21742769 18501503 9482880 14636569 9926942 16677609 26140185 19509300 15571721 16713569 16969499 31073355
P53 RAD51 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16983346 15064730 8617246 11948396 14636569 16600179 12606585 26140185 16713569 11002423 9380510 12750285
P53 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12898523 14627987 9565608 32807901 16713569 9312059 23169665 15044383
P53 AP2A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12226108 16189514 16713569 16288208
P53 PML â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21057547 20972456 11704853 16007146 14976551 25241761 15375079 11025664 22869143 12006491 16713569 12915590 11080164 16189514
DNM3B DNM3A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 14752048 32968275 20923784 12867029 28514442 12145218
PIAS1 DNM3A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14752048 22162396 20966256
DNM3A PIAS2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19786833 14752048 22162396
DAXX H4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21724829 33961781 29084956 23142979 24981860 25416818 27248496 19862764 28514442 12140263 23075851 32545337
RAGP1 RBP2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21518904 11709548 12192048 16204249 26344197 22194619 11854305 9019411 22464730
SRBP1 LMNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19727227 21993218 11929849 16713569
RAD51 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11498787 31270457 19369211 14636569 24085845 29656893 28319063 25659039 34408138 31009828 9774970 16713569 25499220 19766185 17302439 9008167 28976962
JUN BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25609649 12080089 16713569
BRCA1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 9774970 9008167
WT1 ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20842112 18212735
JUN ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1945412 8247540
ETS1 PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10435618 11973649 24448423
ETS1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7848925 8999884
SP100 ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15247905 16189514 11909962
SUMO1 HIPK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16253240 14609633 10535925 21192925 15958389 15896780 24637324 21145359
SMAD4 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
WT1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7559553
TOP1 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15247263 15848144 34079125
PARP1 PIAS4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19779455 20932475
SUMO2 PIAS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22578841 19471022 19394292 20016603 16524884 21252943 18806873 19217413 21693764
PIAS2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14514699
SUMO1 PML â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15017387 15561718 28851805 16501610 19217413 22155184 22875967 24654937 31879127 21779164 20188669 9885291 9452416 17081986 21098080 22406621 18625722 21305000 17344210 17027752 11160742 19380586 23604351 23830076 17081985 9427741 11080164 16189514 23028697 21057547 19015637 20972456 8806687 20826694 24190887 25497731 17036045 11948183 9756909 18474224
SUMO1 RNF4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24844634 23086935 29180619 32296183 15707587 24151981 24907272
RNF4 SUMO1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TOP1 TOP2B â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
P63 P53 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 25417702 11238924 24554706 22575646 23687300 16713569 19345189 21741598
PIAS4 P53 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 15383276 11388671 16713569
PIAS1 SUMO1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
RNF4 SUMO2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
DAXX PML â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
PIAS2 SUMO2 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
SUMO1 JUN â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 11867732 15469925 10788439
UBC9 RAD51 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 24046452 8921390 8610150 16713569
HIPK2 MYB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 15082531 16055500
SUMO1 TOP1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 24654937 11709553 12439742 15576338 12149243 19596686
DACH1 UBC9 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 11025202 16189514 16713569
UBC9 TNR6 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 8940097 9257699 16189514 16713569
IPO13 RAN â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
RNF4 ANDR â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10617653 16713569 11719514 9710597
UBC9 SUMO2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 25027693 26496610 23871147 24969970 20797634 26344197 30574775 16524884 17938407 16713569 31056421 21693764 19471022 30201799 32786267 12924945 28514442 16189514 21949651 17491593 16620772 22578841 11451954 28784659
RAGP1 RAN â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 7744835 8146159 9219684 20805321 10394366 28514442 16189514
SUMO1 SAE1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 15660128 12941704 9920803 12924945 19246003 20164921
SAE1 SUMO2 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
UBC9 SUMO3 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21518904 33961781 25027693 11451954 26344197 17353931 16524884 16713569 12924945 28514442 16189514 21949651 16620772
RAGP1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 16732283 15161980 9658103 16194093 9442102 17000644 18093978 20797634 20414307 24654937 15931224 9497385 9920803 16820290 22751501 24637324 24819975 17060450 9019411 12924945 17099700 15576338 20501649 19246003 16189514 23395904 22578841 18706886 22194619 17099698 16428860 17036045
SUMO1 SAE2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21518904 32296183 25416956 14673145 9920803 10217437 12924945 20501649 19246003 16189514 20164921
DAXX TNR6 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11495919 11773067 25241761 11483955 9990010 20565132 11193028 9215629 11003656 14637155
SUMO1 DAXX â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22578841 31879127 12150977 18583933 20972456 21816224 21474068 11112409 16475184 17081986 30958586 20927612 25409927 19465479 11948183 28851805 23395904 21383010
RBP2 RAN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 7603572 26344197 24855949 11470507 20547757 21988832 10318915 10078529 28514442
SUMO1 TOP2B â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 15161980 21110914 10862613 15561718 19596686
PML SUMO1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DAXX SUMO1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PIAS2 SUMO1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
SAE1 SUMO1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ATF2 JUN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
UBC9 SUMO1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 16494873 16732283 18359863 25502805 10961991 26496610 23871147 26264872 15931224 26344197 9497385 16524884 17938407 9920803 18691969 16713569 9353268 11735126 19684601 21518904 32296183 17353931 8921390 17956732 14673145 19785004 21212807 12924945 22411991 20501649 25416956 16189514 17491593 21949651 21174150 24352468 18264111 18211895
DAXX P53 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 21134643 12482984 15339933 21482821 25241761 16845383 27626385 12954772 15364927 23038753 16713569 28875283 32545337 14557665
SAE1 SAE2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 15660128 33961781 26344197 17353931 12941704 22939629 26496610 10187858 9920803 10217437 26264872 28514442 22863883 16189514 20164921
RAN RCC1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ATF2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10366004 10327051 8530413 12052888 15068801 12751796 9502786 9141200 9252389 11238729 12903123 19255142 11736649 16511568 9819389
SMAD4 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10085140
ATF2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 25609649 20102225 15546613 2320002 10327051 1827203 9445037 26496610 20195357 16511568 20511396 10207054 8027667 23661758 31515488 18641343 1828107
BRCA1 PARP1 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 SUMO3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20016603 25218447 20016594 21147198
BRCA1 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 PARP1 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
HIPK2 DAXX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 19465479 14678985
SMAD4 ETS1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
JUN ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8557686 20195357
SUMO1 HIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21145359 15896780 10535925 14609633
HIPK2 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17081983 27689990 27308327 26539288 19015637
JUN MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1527086 8670250 12475180
JUN SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10220381 9312063 9732876
SOX10 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10973953 10982026 15760336 10938265 16494873 19026785 10942418 16921166
SOX10 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10973953 10982026 10942418 10938265
PARP1 SUMO3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19779455 25218447 23750026 24782567
PARP1 TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 20875401 15911331 15848144 14699148 15247263
PIAS1 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16524884 22578841 19217413 18806873 14609633 11583632
PIAS1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 14514699 21988832 23331499 15028714 15231748
PIAS2 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16204249 21988832 25416956 19217413 16189514 14609633 16524884 12764129
PIAS4 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 12815042 12740389 12904571
SUMO1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 22875967 9756909 25497731 17036045 21057547 18931695 19217413 8806687 16189514 17081985 11080164 11948183 9885291 19380586 17344210
RNF4 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23028697 18708055 15707587 24907272 18408734 21252943 22388745 24637324 19380586
SMAD4 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21836474 21926264 16580992 12524424
PPARG PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18065496 16775433 16425225 23867870 20198337 11378386
PTEN RAD51 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10753747 11747822 12040186 15721744 16288286 16982858 17218252 17218262 18716620 19847259 22179046 22465479 23732914 24254977 25364523
RCC1 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 26186194 10827954 11336674 18617507 10811801 29997244 31467278 16189514 7988569 10369786 20565941 1961752
SUMO1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14514699 23331499 21071413 12813045 12740389
TOP1 SUMO1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12149243 11709553 25114211 10759568
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368