Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MITF HPGDS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15375155 1999537
ATP6V1G1 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PKM RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216198 12620389
PPARG PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18309368
SIRT3 ACSS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16790548 16788062
LEF1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19783677 17945188
CREB1 PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
CREB1 ODC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1356108
CREB1 PKM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20577053 16308421
CREB1 G6PD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17273168 20103717
PRKACA ACADVL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19889959
PRKACA PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8657310 9660757
ODC1 NQO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16205122 15749015
PRKCB MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12917261 9891069
LEF1 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10747853 12048204
MITF GPR143 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19067971 1999537
MITF PRKCB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16411896
NEUROD1 TYRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9447965 14632202
LEF1 NT5E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10428853
PITX2 LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15728254
LEF1 PITX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15728254
CREBBP TCF4 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
EDNRB ATM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GSTA1 GSTA4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ATP6V0A1 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CALM3 NOS1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ACSS1 SIRT3 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ATM CREB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16293623 17209043 15073328
ATP6AP1 ATP6V0D1 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
PFKM PFKP â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ATP6V0A1 ATP6V0D1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TFE3 MITF â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11818452 33961781 28514442 11930005
NDUFAB1 OXSM â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
LDHB LDHA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 25416956 21988832 25910212 22863883 33961781 21516116 22939629
MITF LEF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12048204 12032083
LDHA LDHB â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CALM3 NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7685187 7493936 1722402
CREBBP HNF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10777539
NEUROD1 GCK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14752053 24732800 12540614
PAX6 GCK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15047618 12426319 22778220
MITF TPH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12220516 1999537 9558376
PAX6 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11350962 16189514 12756174
PKM NAGK â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NEUROD1 TCF4 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
PAX6 MITF â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 16189514 11350962
ATP6AP1 ATP6V0A1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
MSMO1 SQLE â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
COX4I1 NDUFAB1 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
COX4I1 COX6B1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
COX6B1 COX6C â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
COX4I1 COX6C â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CREBBP PPARG â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
ATP6V1E1 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CREB1 CREBBP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
ATM HNF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24821553 11980910
ATM CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 16293623 15073328 17525332 15212693 23642045 19115993
PPARG SAT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14506281 14750214
PRKACA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 19007248 11971957 20166139 18767875 20230923 9001246 10576742 23331499 20068231 7935389 18669648 18691976 9922370 15664191 19651622 12801936 9091312 10862777 9710607 11997508
PRKCB RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8288587 1386920 12917261 22826029
COX6C COX4I1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX6C COX4I1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
PPARG PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11278336 16506021 19578162 20234816 10827178 14555539 11412039 19997048 20656057
MAPK8 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9030579
CREBBP LEF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
CREB1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 10866654 18599546 15585582 7870178 8028671 11313407 16007092 8413673 11564156 15691881 9829964 15073328 20403362 11259575 17476304 17707401 20541704 16799563 7870179 11123304 27789289 7913207 12933667 8663317 8004670 11483993 12198160 9413984
SIRT3 ACSS1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 16788062 16790548 21109197 22850421
CREB1 PTGS2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11579131 15187187 15749884 16007092 16713974 17404308 20547845
CREB1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 20954072 21668646 15213229 11092885 18515110 19925797 22919060 17559081 16007171 17505916 17186551 15221958 11668179 11526505 24378735 20032081 17524357 16256955 19797430 16319525 21268077 15289885 17632087 17962194 14645533
CREB1 PRKACA â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 19244110 12150772 12082174 2573431 9733829 17908236 15879576
CREB1 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19937254 10841026 17083486 22496449 19067970 18039926 21519923 16327152 24267286
CREB1 CYP11B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21249615 11196473 20097716
CAMK2G CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11175347 12356771 15733869 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
PRKACA CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11175347 12356771 15733869 11160957 21902831 2885756 2875459 7958915 9829964 12235136 12763014 9687510 8887554 15568017 11698596 8688081 9528766 11018520 11969286 11909979 8336722
PRKACA NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12630910 10400690 1375933 7532810 10874031
PRKACA HMGCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 2369897
PRKACA TPH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9109552 9334190
POU3F2 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18829533 22290434 18628967 24062982
PAX3 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10982026 22290434 10480898 19074888 19403660 9500554 19026785 20925909 11237412 10942418 10644012 21965087 21519923 11830592
MITF PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9466887 23610061 17277739 15978250
MITF TYR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 1999537 12093801 18424413 8995290 23098757 20099279 8707852 17516925 22259223 12136092 12034359 17083486 8645245 20482673 12204775 21519923 15558216 19067971 9170159 12663655 10080955 9647758 14717844 10587587 23876066 9158138 11532965 8749302 20485200 9500554 7969144 23872139 24769727 21910056
MITF TYRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11310793 1999537 22371403 8995290 19067971 8749302 10080955 17457519 12204775 11237412 19995375 12136092
LEF1 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12032083 12048204
PRKCB TYR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10347209