Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CHEK2 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 KAT5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CSNK2A2 L1CAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17253643 8592152
FBXW7 NCOA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18541364
SUMO1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
UBE2I KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
KAT5 SOX10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAGED1 DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
MAPK1 L1CAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
RAF1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 20674547 15664191
MAPK1 L1CAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17151951 21080252
PAK1 RAF1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17097642 5219317
SUMO1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25704882 22493095
SUMO1 NKX2-5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18579533
SUMO1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19788416
YWHAG YAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
OLIG2 SOX10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17098222 20959288
UBE2I NMI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
ASCL1 TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11687288 19399893
SOX10 ASCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12691661
PAX3 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PTN TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAG RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
UBE2I HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25704882 22493095
CTNNB1 WWTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8383887 22234184
WWTR1 PAX3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16300735
PRKCA SOX10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I TRPS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17391059 23772552
SOX10 TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19304657 11044731
DCAF7 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG SOX10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSK3B CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219694 17318191
NCOA2 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12588987 5216126
CTNNB1 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17000761 15729346
PAX3 RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19853745 21677782
PAX3 PDGFRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10411402 9632796
SOX10 PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18184726
TLE1 DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PAX3 MBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22532290 7546735
SOX10 SOX6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17084361
SOX10 COL11A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12783851
SOX10 PLP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799060
SOX10 MAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18634568
SOX10 DCT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14706856
SOX10 GJC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16822525
SOX10 TYR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17516925
SOX10 GJB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11734543
NFIB NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
NKX2-2 MBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19145069 15695521
NFIA NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
GPS2 NCOR1 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
PBRM1 SMARCA2 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
EPAS1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23275444 15261140 22807441 25689462
DCAF7 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35016035 31753913
EPAS1 SUMO1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20026589 20661221
SUMO1 MITF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22012259 16189514 16029420 10694430
YAP1 GSK3B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24976009 29789528
EDNRB EXOC5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NCOA3 NCOA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18267973 11971985
MET ERBB3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25326665 21918175
CIC TEAD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 29844126
NAB2 NAB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
EDNRB PXK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CIC NFIC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 29844126
CIC NFIB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 29844126
CIC NFIX â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 29844126
CIC NFIA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 29844126
BCL7A ARID2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
BRD7 ARID2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30940648 18809673 24657164 24981860 26344197
BCL7A BRD7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
SRPK2 CDK7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32707033 23602568
BCL7A PHF10 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
TRPS1 SUMO1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17391059 23772552
TRPS1 UBC9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17391059 23772552
DPF1 SMARCD1 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
GSK3B CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.84 0.84 Signor 16293724
MAPK1 RAF1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
NCOR2 HDAC2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30737378 16481466 11013263
NCOR2 NCOR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16033423 10944117 11013263
EP300 NCOA2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10490106 9920895 15731352 20448036
YAP1 YWHAG â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5217174 15324660
FYN MAG â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 7525550
ARID1A PHF10 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CTNNB1 TBL1X â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
PHF10 SMARCA2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
WWTR1 TEAD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 25796446 33961781 26186194
SOX10 UBC9 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29295999 16494873
NFIB NFIA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 35140242 33961781 26871637
ARID1A ARID1B â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BRD7 PBRM1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
FYN CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.87 0.87 Signor 12640114
ARID1A BCL7A â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BCL7A DPF2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BCL7A SMARCA4 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ARID1B BCL7A â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
BCL7A SMARCA2 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
SMARCA2 SMARCA4 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
YAP1 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 22234184 8383887
GPS2 TBL1X â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BCL7A SMARCD1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
HDAC2 HMG20A â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ARID1B DPF2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
ARID2 BRD7 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
DPF2 SMARCA2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
BRD7 SMARCD1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
HDAC2 SMARCA4 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CTNNB1 YAP1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
RAF1 FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 16189514 7517401
RAF1 YWHAG â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
NCOR2 GPS2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24943844 33961781 26186194 21240272
UBC9 MITF â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 16029420 10694430
EP300 NCOA3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
TEAD1 WWTR1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CSNK1E WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24715453
EP300 NCOA3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16923966 10655477 9267036 23065768 16227615 20368990 11823864 10490106 25728767 33589584 10866661 15145939
MAPK1 CIC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21087211
PAK1 RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17097642 9823899 12551923 10205168 9234708 11733498
RAF1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15520807 17462920 20363321
YAP1 TEAD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 30417565 35140242 24581491 26258633 27886176 11358867 26933062 31619268 31496812 25751139 29891922 30640473 24882516 25796446 22863277 25751140 32220262 24255178
YAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23607968 22234184 23245941
SOX10 SOD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18786246
FYN GSK3B â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17607942 15676027 15652488
GPS2 NCOR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12628926 11931768 33961781 26186194 14527417
NCOR1 TBL1X â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 15601853 22294699 12628926 10809664 27880911 11931768 10944117 18202150
NCOR2 TBL1X â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12502735 12628926 10809664 10944117 21240272
GPS2 TBL1X â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24943844 26070566 11931768 33961781 26186194 21240272
GSK3B CDK5 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17607942 15676027 15652488
SOX10 EGR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22492709 19922439 12538520
POU3F1 EGR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11782409 19922439 16311519
EGR2 MBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19517016 23874858 7935840
SOX10 EGR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16582099 16311519
PRKCA GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19836308
RBPJ GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PTN GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B TLE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PHOX2B RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21677782 19853745 16127999
SOX10 ERBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11156606 11799060 21672228
PAX3 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8633043 20067553
PAX3 SOX10 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11029584 12668617 10942418
PAX3 FGFR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19100251 25211658
NFIC NFIB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 9099724 35140242 33961781 25258084
SOX10 TYR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17516925 16757562 21210960
SOX10 GJC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16822525 20695017
SOX10 PTN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18786246
SOX10 CHRNA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10559384 19304657 11044731
NFIB NFIX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9099724 35140242 33961781 26871637
NFIB NFIX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9099724
POU3F1 CHRNA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10559384 8144606 8756659
PHF10 SMARCA4 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
PHF10 SMARCD1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
MAPK1 MBP â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
ARID2 SMARCD1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
KDM6A KMT2D â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
KDM6A PAXIP1 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
ARID1B SMARCD1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
HERC1 SOX10 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ARID2 SMARCA2 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
ARID1B SMARCA2 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
ARID2 PBRM1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ARID1A SMARCA2 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
ARID1B SMARCA4 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
NCOR2 TBL1X â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PBRM1 SMARCD1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
SMARCA2 SMARCD1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CTNNB1 GSK3B â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
PBRM1 SMARCA4 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
BCL9 CTNNB1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
DPF2 SMARCD1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
DPF2 SMARCA4 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ARID1A DPF2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ARID1A SMARCD1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ARID2 SMARCA4 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
UBC9 SUMO1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16189514 21518904 22411991 25416956 21949651 17956732 32296183 18691969 16732283 18211895 10961991 21212807 9497385 26496610 24352468 11735126 19684601 17491593 14673145 26264872 9920803 17353931 19785004 23871147 9353268 17938407 16524884 26344197 12924945 16494873 8921390 16713569 18264111 21174150 15931224 25502805 18359863 20501649
ARID1A SMARCA4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMARCA4 SMARCD1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
TEAD1 YAP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDK7 CDK6 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CSNK1E CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 46.0 1.0 Omnipath 9312064 7641885 15265686 19718039 21602792 14966280 210606194 8655584 19705439 11818547 19029934 20093472 17430994 21606194 17884187 11955436 9482734 14747478 17570479 12176352 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 12000790 12114015 16547521 10488109 19020754 20940130 12417018 21640127 21087212 17127310 21796133 10023673
CSNK1E YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 24715453 23431053
CSNK2A2 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19651622 19415658 12082111 16565220 19007248 19691289 18669648 20166139 18691976 17081983 20230923 20068231 18452278 17570479 17287340 19413330 18510355 18212344
CSNK2A2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12700239 19141652 12432063
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
EP300 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9660747
EP300 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15731352 20448036 10490106 9920895
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
PAXIP1 KAT5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
CTNNB1 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9843967 14695187 16510874 15829968 11080158
GSK3B KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22539723 17570479 21658600
RAF1 MAPK1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
FGFR4 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
PRKCA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
RET MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 19901323 11522789 91184134 16156666 16497976 15592455 12571246 19415658 11826406 17389395 18578522 21109534 20068231 18452278 18669648 16153436 11522288 18691976 1378617 15972258 15935618 16094384 12388769 11971971 19651622 21842857 28450419 18707149 17016520 21455180
MAPK1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16039586 28646232 18451303
MAPK1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 17081983 18767875 15849194 19690332 11409918 14654779 23331499 23180781 8226933 20068231 18988627 21917714 18669648 19541618 18691976 16407412 19933846 9922370 15664191 8388392 19651622 10801873 8349614 18775330 9604935
MAPK1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19604315 15542607 16964243 15212693 11604394
MAPK1 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 21887372 10952390 16162175 29121864 9440696 10673502 12819038 20701798 27428965 16246839
MAPK1 MBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 11258664 17255944 12760422 10371216 12944901 1939237 9792705 16401070 15380617
CDK5 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 20058876 17114649 12176333 12950086 19298660 19664994 12176334 15542607 19413330 23537649 19036346 19664995 21825040 11604394
PAK1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 28007610 28423670 23543898 25639486 26547035 22369945 23162742 25472536 21822311 25225063 27713506 27910850
PAK1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 67.0 1.0 Omnipath 28007610 19421139 26333361 22096607 15849194 12952546 30197477 12551923 23162742 25733387 17097642 22105362 18465753 23331499 24924700 10801448 26257058 21917714 12719581 11376654 25843685 15664191 19165420 23576562 23506953 10205168 24505617 28415790 18775988 22983922 9234708 12952943 16129686 25472536 11733498 11948406 9823899 11897507
EGR2 SMARCA4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10757804 16373334 17325040 23874858
SMARCA4 SOX10 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10757804 16373334 17325040 23874858
SMARCA1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23609547 24285714 20015969 17023429
SMARCA4 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11532957 14964309
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
YAP1 SOX10 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11394999 28852375 14664827 22492709 12056842 21411665 27288457
YAP1 WWTR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 12807903 18280240 18617895 21666501 23708000 25502501 26711338 7782338
YAP1 WWTR1 â—¼   PROTEIN_INTERACTION 8.0 1.0 ACSN 12807903 18280240 18617895 21666501 23708000 25502501 26711338 7782338
YAP1 TEAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22863277 11358867 25751140 30417565 24882516 26258633 23431053 24581491
GSK3B CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 11152665 20537194 10385618 11124803 12969793 19757160 16732330 10486203 16039586 14536078 18167338 12459251 12615961
CDK6 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17208333
NMI SOX10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16214168 17145710
FYN CDK5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 24872417 19901323 9038181 10896159 18691976 20506281 29063113 20068231 16497976 19413330 14757045 12372285
FYN MAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16713569 7525550
FYN CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 20026641 22264731 24511551 25241761 22340496 12640114 25803041 26509276
PRKCA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 1386920 23331499 9447975 8321321 12551925 8288587 7935389 12917261 9922370 15664191 93309588 1437148
RAF1 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17353931 11697890 8702721 10433554 16189514 15664191
SOX10 HDAC2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 26423937 12198163 10856243 21423190 21653862 17699610 22814607 18803322
NCOR1 TBL1X â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 NCOR2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
NCOR1 NCOR2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
NCOR1 TBL1X â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 RBPJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18391971 9694793
TBL1X CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11389839 25241761 20181957 33054136 18193033
BCL9 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17145710 15294866 23331499 11955446 17052462 15371335 24360964 15208637
GSK3B SUFU â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17444818 27234298 16611981 20537194 10671551 20080742 19797085 16039586 19575820 21317289 12040186 17052453 12615961 18455992 16371461 11274345
EGR2 WWTR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11394999 28852375 14664827 22492709 12056842 21411665 27288457
SOX10 WWTR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11394999 28852375 14664827 22492709 12056842 21411665 27288457
CDK5 ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12824184
EGR2 NAB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16136673 25974668 11734543 8842374
EGR2 SOX10 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16136673 25974668 11734543 8842374
EGR2 TEAD1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11394999 28852375 14664827 22492709 12056842 21411665 27288457
EGR2 NAB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19706684 9774344 18203138 18096076 20506119
PRKCA MBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10460230 2413024
PRKCA MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 17496910 11940581 21386996 15075332 11447289 19615955 8294430 16488589 6321473 8321321 12845332 11313945 17570479 94124523 12040186 19568798 15567848 14585353
PRKCA GJB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8390988
UBE2I MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10673502 16713569 10694430 16029420
GSK3B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 183.0 1.0 Omnipath 22415718 11967263 27158593 29455668 19303846 19797085 8638126 19293931 23056571 22662165 25352148 16611981 27068260 28337019 10671551 21743491 20688898 16293724 23721711 23552738 18687691 28977889 19622173 12051714 25241761 27683053 28549350 22699938 19565571 23076981 21562161 19575820 20219694 20537194 10330181 21986938 29183346 27773936 11251183 19711366 21035499 19675674 7542250 23151663 24451375 14663202 23804296 8524413 25639486 23770025 18070361 26892600 30143633 9233789 19667122 27507058 19061640 19223551 29387014 23331499 16199882 11533658 18644116 24501426 24913829 11835406 17318191 26014148 25366337 28183999 22640743 26910375 12000790 12114015 18387957 19107203 9832503 16371461 29805709 27462866 20137080 27902311 12040186 19576224 25644994 12615961 19060929 25897075 12851486 15465828 17053159 18952601 10228155 15020233 17444818 20140245 26453498 17052453 16944320 24015932 23602568 24975844 24931005 28948000 20080742 23209942 30271168 28220106 16520547 28430641 11818547 25546293 27672271 11955436 11154277 26373837 16039586 23778311 28697793 20302655 25136145 26905812 22216350 8666229 12957350 23109003 10074433 28529629 20215423 21329734 11254732 9501208 27098453 27281614 30279527 19631635 25482131 18455992 24403311 11274345
GSK3B ZNF281 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 29179460
MET CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17496910 25163657 24511551 22558232 11929826 16909210 24342833 12040186 26654598 19568798 14585353 23083465
MAPK9 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 19623618 18423204 25639486 22074626 19667122 18604449
RBPJ NCOR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17145710 11509665 23331499 18391971 9694793 10713164 21475249 11404076
SOX10 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10973953 10982026 15760336 10938265 16494873 19026785 10942418 16921166
POU3F2 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18829533 22290434 18628967 24062982
PAX3 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10982026 22290434 10480898 19074888 19403660 9500554 19026785 20925909 11237412 10942418 10644012 21965087 21519923 11830592
MITF BEST1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1999537 14982938 19067971 17085443 18849347 20530484
MITF MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1999537 17371876 19067971 20068147 20067553
MITF DCT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11310793 1999537 12032083 22371403 8995290 15250937 14706856 11543611 12753399 15892717 19067971 19995375
MITF TYR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 1999537 12093801 18424413 8995290 23098757 20099279 8707852 17516925 22259223 12136092 12034359 17083486 8645245 20482673 12204775 21519923 15558216 19067971 9170159 12663655 10080955 9647758 14717844 10587587 23876066 9158138 11532965 8749302 20485200 9500554 7969144 23872139 24769727 21910056
SOX10 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10973953 10982026 10942418 10938265
SOX10 RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20977903 11032856 14523991 19853745 21677782
SOX10 RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12668617 11032856
TEAD1 SOX10 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11394999 28852375 14664827 22492709 12056842 21411665 27288457
NAB1 NAB2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 16136673 20506119 16574654 8668170 7624335 9774344 16260776 8413279 10734128
SOX10 NAB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16136673 25974668 11734543 8842374
SOX6 COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16465043 20181744 9755172 10980415
SOX10 EDNRB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16921166 16623715 16412618
SOX10 EDNRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15170213 16623715
NFIB NFIC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9099724 25258084 16189514
SOX10 NAB2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16136673 25974668 11734543 8842374
SOX10 POU3F1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 19922439 21423190 21423191 22814607 16311519 18803322
SOX10 GJB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15470753 11734543 16494873 21918739 16822525
SOX10 DCT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15250937 14706856 11543611 1999537
SOX10 MPZ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10931919 16373334 19487693 14523991 23874858 18634568 21179557
SOX10 MBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11734543 12643284 18160645 23874858 15523643
SOX10 MPZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10757804 17325040
SOX10 MBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18160645 15523643 11799060
MBP PLP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 2467009 6083474 16713569
POU3F2 POU3F1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 19922439 21423190 21423191 22814607 16311519 18803322