Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
ABL1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN CBL â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 5220480 7642581
LCP2 CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6548125 9716598
FYN CBL â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CBL FYN â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
JAK2 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
JAK2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
AKAP2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
TEC GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 11406363 15214048
GRB2 CBLB â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PLCG1 LCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6546918 15929943
LCP2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6546918 15929943
TEC LAT â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 11406363 15214048
PLCG1 EPOR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15644415 8034732
PLCG1 AKAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
TEC PLCG1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 11406363 15214048
TEC PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10823839 24317039
EPOR PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15953601 15329338
FYN CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
SOCS1 JAK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10421843 6731094
EGFR JAK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
PGFRB FYN â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 1696179 16189514 16713569 7687537 9425276 7520528 7685273 1661130
BLNK KSYK â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16189514 21482705 10981967 18369315 21822214
EGFR HNRPK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28065597 15657067
EGFR TBB5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23956138 15657067
RAC1 GRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 31980649
VAV SBSN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HNRPK PLCG1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VAV NUB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VAV ARF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32203420 31980649
VAV PGFRB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22974441 10938113
VAV AKAP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VAV ACTBL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VAV SPA12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VAV S61A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32203420 31980649
VAV APLP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VAV ACTA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VAV PLBL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VAV CDSN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VAV KLK7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VAV GHC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32203420 31980649
VAV AT2B2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VAV CYTSA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VAV DR9C7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GRB2 ZAP70 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23267066 7629168
LAT SLAP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10449770 16189514
EPOR PLCG1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15953601 15329338 15644415
TYK2 VAV â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10673353 16189514
BLNK VAV â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 9697839
VAV EPOR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9162069 16713569
MK01 VAV â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9013873 8900182
SLAP1 KSYK â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10449770 16189514
CBL LCP2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ABL1 EGFR â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
FAK2 CBL â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15128873 12771190 11149930 16713569
PGFRB EGFR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9506992 7531698 16713569
LAT LCP2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24584089 16189514 9489702 23514740
LCP2 KSYK â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15388330 16189514 22267732
ZAP70 FYN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 7760813 16189514 16713569
PRLR JAK2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9202403 10772872 20962278
VAV RAF1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 8900182
SLAP1 ZAP70 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10449770 16189514
CBLB ZAP70 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10074432 21453975 16189514 33848699
TEC VAV â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11328862 7651724
SOCS1 P85A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10022833 25814554 29991678
PGFRB SLAP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9742401 18193084
VAV TBA1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 8530437 31980649
EGFR PLCG1 â—¼   PHOSPHORYLATION ✅ + 0.84 0.84 Signor 1689310
ABL1 PTN6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10488096 8692915 7512963 10574931 8114715 12468540
PLCG1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 9020117 6805619
KSYK GRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 22267732 11964172 10747947
LAT ZAP70 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
KSYK CBLB â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12771181 10022120 16189514 27428901
CBLB P85A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11526404 10022120 9614102 19190244 10086340
BLNK PTN6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15588985 10903736 16189514 11356834
RGAP1 VAV â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10748082 16189514
VAV TBB5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8530437 31980649 9880513
SOCS1 EGFR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22973453 29991678 12070153
FAK2 GRB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 10354709 19380485 10329689 8695788
ZAP70 LCP2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10660534 8702662 24584089 9047237 12190313
ZAP70 PTN6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10458769 16189514 8638162
P85A CD19 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15187135 7684160 7528218
VAV CD19 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15187135 16289966 7528218
FAK2 VAV â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10867021 16713569
3BP2 CBL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9846481 20439986
EGFR RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
SOCS1 GRB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10022833 29991678
ZAP70 LAT â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16906159 12186560 11368773 23514740
ZAP70 PLCG1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16467851 7629168 8906806
VAV JAK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9162069 7530656
TEC JAK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9473212 9178903
JAK2 RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9689060 11134016 8876196 10205168
PGFRB RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23397142 16189514 2475255
KSYK 3BP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9846481 11390470 12709437 20439986 15345594
PTN6 FAK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10521452 10747947
LCP2 ZAP70 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BLNK GRB2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ABL1 PLCG1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10708759 1383690 17474147
LCP2 CBL â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10477741 10204582 9716598 19635790
JAK2 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24240702 9363897 10635327 16273093 23838182 10358079
FAK2 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10980697 16713569 10777553 15657067
LCP2 P85A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21282515 15388330 15929943
3BP2 PLCG1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9846481 15345594 11390470
SOCS1 FYN â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10022833 16713569 29991678
JAK2 FYN â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 10551884
TYK2 PTN6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 8780698 7629131
CDC42 RAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
3BP2 ZAP70 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9846481 11390470
SOCS1 TEC â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29991678 9341160
SOCS1 VAV â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10022833 10747851 29991678
PRLR VAV â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 7768923 11328862
KSYK PTN6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 34362877 10871605 10747947 10072516 11356834
SLAP1 VAV â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 10662792
ACTBL ACTA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
LCP2 PLCG1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
LAT PLCG1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CBL PLCG1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
ABL1 GRB2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
VAV ABL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19234221 11790798
SLAP1 CBL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16327786 10449770 18193084 17237826
SLAP1 EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31980649 22973453 24658140 16273093 25402006
CBLB EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24797263 11375397 20308550 19531499 33848699 10635327 30515972 18271526 28572092 10086340 16729043 31959764 16702950 15657067
EGFR LAT â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
EGFR LCP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
GRB2 LCP2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
EPOR GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 7534299 9129019 8647802
LCP2 PTN6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9765283 15588985 16189514 8760799
P85A FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25416956 16713569 8294442 7520528 8394019
KSYK FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 16189514 9535867
TYK2 FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9196040 16189514 16713569
RAF1 FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 16189514 7517401
P85A JAK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17474147 8702385 16135792 10026141
PTN6 JAK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8943354 10772872
RAC1 P85A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8034624 12086876 25284480 32814053 7629060 31871319 26475863
CBLB VAV â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11857085 16189514 9399639
SIAH2 VAV â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10207103 16713569
PTN6 P85A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11337495 9452499 11160222 10488096
VAV P85A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9162069 16713569 9891995 17050525
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
ABL1 GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23950177 16713569 17474147 14725908 9407116 9516488 8194526 19380743 19823681 7926767 16955467
ABL1 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 16273093 25402006 7678409
ABL1 P85A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 1383690 16135792 8781408 17474147 8294442 16219545 19380743
ABL1 CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15556646 11494134 16713569 9174058 20675402 9195915 14604282 10829062 14725908 8626543 12475393 19380743 19823681 16955467
EGFR CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27059931 7657591 8665853 27903975 15107835 24797263 28791635 9756944 23799367 23175185 28198003 12734385 14505571 20940296 19155296 10635327 15117950 22833562 29629558 12061819 8662998 10086340 33762435 11994282 20877636 32714745 25005938 31182136 19578043 7782294 24714105 10799548 23158001 26055326 33617900 23153581 15210722 25872741 15657067 19947936 10428778 18508924 16969069 17971399 15962011 19531499 25521828 23774213 22976291 31959764 22591401 18255265 15735736 16713569 20562913 17880946 16914641 9890970 22394513 16729043 32114396 17995934 17182860 18319245 18271526 17545148 15383614 25140053 32377695 15465819 33627783 8798643 25754235 15282549 26177020 22266821 16923119 17242169 30544639 12604776 11239464 9130710 19225046 11370743 21772844 16105874 18273061 7592693 23897813 17486068 16246327 23457600 32904620 12803489 31120930 15668240 22203672 23418353 20124286 28541302 33323455 10092522 14627991 15677445 15159412 20308550 16849543 12593795 19836242 9121472 19713535 18316398 11408594
ZAP70 CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16503409 9407100 22266821 8798643 10779765 11353765 9988730 10074432 10078535 29053960 11133830
CBL P85A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11030146 10918571 17237826 16982329 14530346 9174058 9918857 11418612 11087752 9890970 25814554 9178909 15581361 9890943 19861161 15107835 9259313 8612729 9414268 7544353 21203488 18374639 8695807 10620516 7791764 10025673 9160881 8941725 8896416 8662998 9461587 16219545 11042121 19380743 19190244 16289966 7642581 11994282 8702998 11157475 11944898 9092538 16135792 15556646 16713569 8621719 9541596 24113870 33512474 9988765 9234717 8995243 11133830 10358153
CBL VAV â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16356860 16713569 9200440 18835194 19635790 11331248 16289966 11133830 12881521
VAV EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 10938113 22973453 24658140 16273093 25402006
PTN6 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9733788 22973453 25187647 7673163 28065597
P85A EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21701776 25241761 16713569 7499252 19531499 22973453 25187647 8662998 16273093 25754235 7797556 31959764 16230374 7531698
ZAP70 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 22973453 24658140 16273093 25402006
EGFR PLCG1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 1689310 11983899 14568990 15144186 12803489 12601080 24797263 9756944 9207933 19605547 7993895 7693694 9020117 12061819 16273093 25754235 16713569 22973453 7682059 8657103 8885868
EGFR TBA1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24189400 24658140 25402006 16799092 15657067
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PGFRB GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7935391 7486683 16189514 16713569 9362449 10026169
LAT GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7544353 16906159 12186560 16189514 9489702 16713569 8063801 16938345 10811803 12359715 23460737 11368773
JAK2 GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7500025 17474147 8536716 8950973
EPOR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8647802 16713569 7534299
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
LCP2 VAV â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 10347175 9341187 21725281 8703037 19635790 11331248 9047237 8673706
LAT P85A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7544353 10811803 11368773 16713569
LAT VAV â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17306257 12186560 11368773 16713569
LAT 3BP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9846481 17306257 11390470
FYN LAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16938345
ZAP70 VAV â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 9151714 16339550 7798261 8530437
P85A CDC42 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8034624 7629060 25284480 31871319 9381982
EZH2 VAV â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15882624 8649418 16189514 10780782
KSYK VAV â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 8900182 11331248 8986718 11262396
3BP2 VAV â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17306257 20439986 15345594 11390470
PGFRB P85A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10752619 7536927 9153411 8382612 10697503 1314164 15377662 8388538 19864249 11710529 1330535 7680644 7678051 7531698 1372092 7486683 16135792 16713569 8564419 7692233 11896612 8670861
TBA1A TBB5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24688049 15121898 22863883 33961781 30274285 34079125 22939629
CBLB ZAP70 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ABL1 CBL â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
PLCG1 JAK2 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 17474147 14978237
JAK2 SOCS1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
LCP2 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 17235283 5219525
MK01 RAF1 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 10958680 16093354 15664191 19058874 11409918
PTN6 VAV â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 16189514 8632004
EGFR PLCG1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
CBL FYN â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
HNRPK FYN â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 16189514 16713569 7516469 9185665 31413325
PTN6 PGFRB â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 19167335 9452499
P85A KSYK â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 15536084 16921024
GRB2 HNRPK â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 25416956 31980649 12577067 21988832 19380743 20936779
KSYK PLCG1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 1689310 7682059 8657103 7831290 15144186 8885868
PLCG1 VAV â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 16467851 16713569 9891995
VAV FYN â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 9822663 16189514 11262396 16713569
VAV CDC42 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 11287617 16189514 18511940 32203420
HNRPK VAV â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 7862126 16189514 16713569 8051112
CBLB EGFR â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
GRB2 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5220480 7642581
EGFR CBL â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 16729043 5218694
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
CBLB GRB2 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
PLCG1 GRB2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16713569 7629168 7516467 9020117 21706016 10940929 16038803 9281317
PTN6 GRB2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10660620 16189514 8632004 11964172 25535246 10747947
PGFRB PLCG1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 7486683 1396585 16713569 22974441 8443409 23063561 11896612 7678051 15641795 23397142 9797459
SOCS1 JAK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11314018 14517242 14522994 10421843 19287004 29674694 10064597 18508766 9202126 9344848 11971965 11713228 29991678 28258213 10455112
JAK2 EPOR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 14982882 12441334 11779507 8343951
VAV RAC1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16397238 11287617 32203420 18511940
P85A EPOR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9162069 16713569 24113870 12506011 7559499 15644415
PTN6 EPOR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 7528537 7228577 7889566 7528577
FYN CBL â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17094785 8900205 15190072 9890970 25814554 8995358 12244174 10829062 12941616 9311917 12231245 16503409 9677430 8662998 119942 9535867 10092522 15208330 7642581 15556646 16713569 8621719 10629042 7782294 8626543 10799548 11239464
KSYK CBL â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 7721825 12435267 15556646 18273061 27614019 8621719 15536084 31120930 15577829 11331248 10617633 11742985 16289966 11042121 9857068 11133830 10570266 10540342
PLCG1 CBL â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503409 12803489 9712732 25241761 16713569 16467851 12061819 12941616 9234717 17372230
EGFR GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19254954 7518560 31980649 9416834 7592693 23956138 14679214 10085134 7510700 27059931 21706016 25402006 16799092 16729043 8665853 15657067 24797263 12577067 8810325 7650032 11960376 23799367 25187647 8626525 10026169 19289468 18271526 21278786 7506413 17971399 8940013 20124286 11726515 9886492 10595738 24189400 9020117 19531499 20473329 9020193 8662998 8647858 1322798 8887653 10229072 16273093 25754235 31959764 11370743 16713569 21596750 9685397 24658140 31985874 22973453 11896612 20067773 17242169 19836242 8810340 21278788 30544639 7527043 9050991 11408594 8621459
LCP2 GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 8695800 11314042 10204582 8995445 15929943 12176364 25416956 32296183 9565634 10224278 7706237 20936779 19380743 17235283 9716598
VAV GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 16713569 8900182 8647120 9013873 7809090 18692475 29997244 16339550 15558030 32203420 10207103
P85A GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25416956 9174058 11418612 21706016 7544353 18346204 7737969 9886492 16219545 19380743 7642581 7759531 16713569 8621719 7642542 9541596 8647120 32814053 20936779
BLNK GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 9697839 16912232 10820378 9705962 21822214 10556826 11449366
LCP2 PLCG1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11390650 15929943 21725281 16467851 7706237
LAT PLCG1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 7544353 9489702 16713569 16467851 16938345 10811803 27221712 24642916 9729044 11368773
FAK2 FYN â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32707033 16713569 9091579 10229084 9104812 10867021 31413325
EPOR JAK2 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
CBL ZAP70 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CBLB GRB2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 21900206 28514442 16189514 25416956 31980649 12577067 31467278 26264872 10022120 9614102 29997244 21706016 32814053 33961781 20936779 10086340 27107012
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ABL1 CBL â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
FYN ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12522270 16787943 17570479 16912036 16076903 17474147 11847100
ABL1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16705159 15923602 15793561 25821558 9111318 15143187 16705160 11593427 20841568
ABL1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 9525940 11494134 16713569 20841568 10829062 17389395 16955467 12604776 9890970 10391678 9195915 14725908 7925293 11997497 12522270 15556646 9102067 11239464 11994282 9174058 12475393 20675402 19380743 14604282 8626543 15212693 19823681
ABL1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 11726515 16713569 20841568 8596638 16955467 10592173 8647802 8194526 7926767 14725908 23950177 8112292 9407116 23181695 19380743 17474147 9516488 19823681
ABL1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 10708759 19290927 12652307 1383690 16525023 8657103 20841568 17474147
ABL1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 24430869 15192046 33889303 16273093 16943190 14760089 29880877 15618223 33574089 8910327 12631709 25173817 25402006 20841568 33947961 34107301 34469737 19915609 32019812 2022651 34290403 33707748 15329413 7678409 9733788 8490966 28338646 3263271 15901825 2022652 10069801 7506413 24658140 8408058 34385595 31980649 1314835 7741752 18668345 28724430 12648464 25073158 26079946 34155348
ABL1 CD19 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11120811 20841568
GRB2 CBL â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 31980649 8649804 8995445 25036637 23799367 11997436 8943292 9242692 10570290 8662998 11399323 10086340 7642581 9108392 20936779 11133830 8626404 17094785 8063801 9129019 8900205 15210722 8621483 25872741 25814554 9178909 16906159 8950973 17971399 10025673 9295052 19380743 9716598 16713569 11964172 9234717 8083187 7537740 8824292 9259313 9311917 7791764 17072306 14725908 33627783 9461587 9434624 9851874 8695851 12839496 17944804 11792427 10204582 8621719 11823423 9541596 33961781 169092 11263968 98621719 28514442 18273061 7592693 9174058 21706016 8995358 9872323 9233773 9367879 7544353 12941616 10829062 20124286 917890 15677445 9092538 10521482 8647120 19836242
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
CBL ZAP70 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11353765 15169881 18835194 20189481
FYN CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 97.0 1.0 Omnipath 9525940 7642581 8626543 7782294 15208330 16503409 16713569 10829062 10799548 10934191 8900205 8551236 8662998 8995358 19734451 12604776 9890970 10592173 17570479 10629042 17094785 10092522 11997497 12522270 15556646 12244174 8621719 9102067 22880054 9311917 11239464 19904769 11994282 12941616 9535867 25814554 12231245 15190072
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CBL ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 11133830 10779765 10358158 16503409 8798643 20189481 22266821 23109003 18835194 10074432 10078535 15268851 15169881 26192618 9407100 9988730 11353765
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
CBL PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 7517397 9712732 12941616 25241761 12061819 23109003 9234717 16503409 11709089 16713569 17372230 16467851 12803489
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
CBLB EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17145710 19531499 11375397 10086340 12577067 10542134 17635922 10514377
JAK2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17389395 10635327 17081983 10358079 16273093 16799092 18691976 10459005 9363897 15284024 23838182 17016520 18669648 15302935
EGFR PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 89.0 1.0 Omnipath 19901323 17081983 16273093 9207933 2472219 16497976 15592455 16126727 16713569 24797263 17389395 8578591 23331499 7991458 1689310 20068231 17570479 9176240 12803489 16153436 7993895 16038803 7805859 15864276 1708307 7682059 15144186 11983899 12601080 9756944 15212693 14568990 12061819 9020117 8885868 12648464 8657103 15951569 17016520 7693694
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR ARF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12446727
GRB2 RAC1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 LAT â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 RAF1 â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11532940 11777939 11907067 12040186 12175651 12419216 12479806 12566895 12640133 12782630 14585353 14764585 15169888 15516985 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17673906 18039929 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9069260 9510155
GRB2 PLCG1 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 LAT â—¼   PROTEIN_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 RAC1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 PLCG1 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 RAF1 â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11532940 11777939 11907067 12040186 12175651 12419216 12479806 12566895 12640133 12782630 14585353 14764585 15169888 15516985 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17673906 18039929 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9069260 9510155
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
ZAP70 GRB2 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
GRB2 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 LAT â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 LCP2 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
BLNK GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21822214 11449366 10820378 16912232 9697839 16189514 10556826 9705962
LAT GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 11368773 9489702 10811803 8063801 17043143 16938345 16713569 23150273 12186560 16906159
CBLB GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 10022120 25416956 21706016 31467278 32814053 9614102 17635922 11375397 8626404 16189514 21900206 20936779 27107012 12577067 10514377 19531499 10086340 29997244
LCP2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 7706237 20936779 10224278 8695800 17235283 15929943 25416956 19380743 9716598 32296183 10204582 11314042 8995445
JAK2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8536716 8950973 7500025 17474147 19273609
GRB2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9281317 15953601 7629168 9020117 16713569 10940929
RAC1 LCP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17540168 11278486 11804587 12670394
ZAP70 LCP2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 12415267 12731048 15735648 17371980 20814939 23620508 7600293 8642247
PLCG1 LCP2 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
LAT LCP2 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
FYN LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10648627 9047237
ZAP70 LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 12817019 9047237 15388330 10660534 15286727 23109003 8892604 12640133 12640123 11323691 8702662 23758320
LCP2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 12941616 9341187 23109003 21725281 15929943 11709089 16467851 11390650
PLCG1 LAT â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
LAT RAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17540168 11278486 11804587 12670394
PLCG1 LAT â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
PLCG1 LAT â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
ZAP70 LAT â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 12415267 12731048 15735648 17371980 20814939 23620508 7600293 8642247
ZAP70 LAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 24412752 15659558 10811803 27896837 11395491 15084594 16906159 15029250 27700984 12496416 34161759 11368773 30510001 23109003 22507872 18779373 33931484 23758320 15100278 24642916 23150273
LAT PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 27221712 11368773 9489702 12941616 15286727 10811803 23109003 24642916 16938345 11709089 16713569 15219999 16467851 9729044
ZAP70 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
JAK2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17474147 14978237
FYN PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8395016 10586033 7682059 16713569
BLNK PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9697839
CBLB FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15208330 16503409 32296183 25814554 8083187
FYN ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7760813 16713569 16839418
JAK2 TYK2 â—¼   PHYSICAL_INTERACTION 73.0 1.0 ACSN 10485906 10807786 11160275 11306493 11371360 11867689 11870632 12223527 12244147 12372421 12401408 12496409 12754507 12818165 1439146 14610620 14657224 15099563 15356132 15546391 15573129 16243976 16413922 17404308 17485448 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21042762 21097505 21115385 21469115 21840487 22077060 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24204259 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8683106 8700208 8837607 9535722 9834059 9845545
JAK2 TYK2 â—¼   SHARES_COMPLEX 73.0 1.0 ACSN 10485906 10807786 11160275 11306493 11371360 11867689 11870632 12223527 12244147 12372421 12401408 12496409 12754507 12818165 1439146 14610620 14657224 15099563 15356132 15546391 15573129 16243976 16413922 17404308 17485448 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21042762 21097505 21115385 21469115 21840487 22077060 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24204259 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8683106 8700208 8837607 9535722 9834059 9845545
SOCS1 JAK2 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 10485906 12193701 12223527 12811837 21469115 23124025
PRLR JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 9202403 21071413 17312100 18988627 20962278 11713228 10772872
SOCS1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 10421843 23331499 21071413 10455112 14522994 10064597 28258213 19287004 18508766 11314018 18988627 11971965 11713228 10975987 9202126 9344848
JAK2 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 11134016 8876196 9689060 10205168
JAK2 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 27468692 27494834 25038756 24469040 30159126
JAK2 TEC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9473212 9178903
JAK2 EPOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 10660611 12441334 7559499 8343951 18672044 11779507 12027890 11443118 12524467 9030561 9573010 15212693 10579919