Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EPOR CRKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11443118 11124936
JAK2 CRKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11443118 11124936
CRKL IRS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11443118 11124936
CRKL ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
CRKL ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
SOS1 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11707404
GAB1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11707404
ABL1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
FYN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ERBB3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17308105
BCR CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8978305 21602891
CSF1R CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8981370 20489731
FYN CBL â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CBL FYN â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CBL SRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219404 17141222
CBL MET â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5215187 11894096
CBL ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
SRC CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17094785 7033811
GRB2 CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CBLB â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CD28 CBLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12193687 23109003
CBLB MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8083187 11904433
CBLB ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
LCK CD28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
FYN CD28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
CD3E SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731413 11855827
LCK CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
FYN CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
SRC CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
ERBB3 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
GHR CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ERBB2 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
CRK TPX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN CSF1R â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6730431 7681396
IRS1 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
EGFR IRS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
GRB2 ELK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
EPOR SOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
EPOR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 8400282
ERBB2 SOCS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB2 IRS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB2 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11173924 16713569
GRB2 ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16729043 5218694
SRC ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB3 JAK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB3 FGFR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB3 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16273093
ESR1 RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21118977 11060289
FGFR1 SHC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 17496910 25467007
FGFR1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9480847 16713569
SHC1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7516469 5220322
LCP2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6546918 15929943
LCK FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
FYN LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 22043010
KIT GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16873377 18697750
SHC1 GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10704825 5212298
GRB2 GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212828 10913131
RET GRB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7665556 8631863
IGF1R GRB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6547677 9506989
GRB10 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
LCK GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
GRB2 TPX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
IRS2 IGF1R â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8662806 5221055
SHC1 INSR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805769 9593725
RHOB INSR â—¼   COLOCALIZATION 2.0 0.8 intact 14722096 6672086
NTRK1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11147812
IRS1 IRS4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11912194
SOS1 IRS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
JAK2 IRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15316008 12960006
IRS2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11505033 15705774
JAK2 SOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
SRC JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 17158356
LAT SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10811803 8663278
SRC LCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6546918 15929943
SHC1 LCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6548125 9716598
SOS1 SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9544989 6547749
SOS1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC TLR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218855 16858407
TLR3 SRC â—¼   COLOCALIZATION 2.0 0.8 intact 5218855 16858407
CRK GRB2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
EGFR JAK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
GRB2 MET â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
PGFRB FYN â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 9425276 7685273 1696179 1661130 7687537 7520528 16713569 16189514
KIT CBL â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 25737303 16780420 15315962 8950973
LCK CD3E â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 11855827 14523017
FGFR1 CRK â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 10464310 25241761
SHC1 FGFR1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 7559490 7514169 16713569 18022941 16189514
GRB2 RET â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
CRKL SOCS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25814554 29991678
IRS4 P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
RN19B P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FLRT1 P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
HAVR2 P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
I20RA P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DP13A P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25814554 12621049
FLRT1 P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SNX32 P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CUL3 P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27708159 21145461
NISCH P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27173435 32203420
TPX2 P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17474147 32203420
LZTS2 P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29395067 33420362
DEF5 P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RN19B P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
P55G P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
P85A CTLA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 9813138 7807015 9398332
P85A TGON2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 17474147
P85A RET â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10652352 10995764 32062451
P85A SHIP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 9918857 12506011
P85A GRB10 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12783867 23246379
SRC PTN11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 8959326 14687660 20308328
NTRK1 PTN6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15557341 29715200
FAK1 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22402981 10733346
SH3K1 PGFRB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12177062 16189514
PGFRB ERBB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30898150 7531698
VAV PGFRB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10938113 22974441
RASH CDC42 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30194290 30442762
ADA12 GRB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25825872 11127814
HAVR2 PK3CB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CRK PK3CB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19380743 31980649
FLRT1 PK3CB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
I20RA PK3CB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RN19B PK3CB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GRB2 1433G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21706016 31980649
1433G LZTS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FLRT1 P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HAVR2 P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
P55G NISCH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SRC P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25814554 22402981
IRS4 P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
UFO SOCS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12470648 29991678
IGF1R CTNB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22261717 27684187
CTNB1 LZTS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 34079125
I20RA PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RN19B PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FLRT1 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF5 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HAVR2 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HAVR2 NISCH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOS1 BCR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 8112292 7529874
RHOB BCR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
NTRK1 CBL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21570973 25921289
IRS4 EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16273093 24797263
RHOB EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
EGFR IGF1R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
IGF1R ERBB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30898150 17307140
MET ERBB3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21918175 25326665
RAC1 GRB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 31980649
RHOB IRS4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
LCK LZTS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25416956 34079125
RHOB NISCH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB SRC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
P85B P85A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 32203420 26186194 28514442 19380743
P85B P55G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19380743 26186194
P85B SHC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 8662998 19380743
TGFR1 P85A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15657037 9435577
PCBP1 P85A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ICOS P85A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27135603 18641334
VSIG4 P85A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
P85A ELK3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25416956 17474147
FCG2A PTN11 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PK3CA PTN11 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 9565634 26839216 9660791
PTN6 GAB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11895767 11812650
FAK1 JAK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 9553131 10925297
KHDR1 SH3K1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19531213 22745667 31413325
MK08 CBL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16982329 11944898
SH3K1 SOS1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16713569 11071869
CBL PK3CB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33864160 19380743 14530346
TGFR2 PK3CB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
GRB2 PK3CB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 21706016
PCBP1 PK3CB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
GAB2 1433G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 19172738 33961781
GRB10 1433G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32814053 28514442 33961781
1433G IRS4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25036637 15324660
TGFR2 P55G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SRC UFO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 9178760
TGFR2 ERBB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 FGFR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CTNB1 MET â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11929826 11254878
VAV EPOR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 9162069 16713569
IRS4 PK3CA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 11912194
PCBP1 PK3CA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
GRB2 PK3CA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 21706016 9565634 32814053 28514442 19380743
LAT FCG2A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10781611 16189514
SHC1 ABL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10194451 19380743 8112292
CBL BCR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20675402 8621719 14725908 8641358 19380743
BCR KIT â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 8757502 25241761
KIT CBLB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12177062 15315962
SHC1 EPOR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 8400282 16713569
INSR JAK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12456798 8912646
IRS2 NTRK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11147812 25921289
LCP2 SHC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 9716598 16189514
PCBP1 MET â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
EGFR GRB10 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
GAB2 SHC1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CBL LCP2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ABL1 EGFR â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
GAB1 RET â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19914172 32062451 11360177
P85B IRS1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11120660 30240640 12730242 23604317 7559478
FAK1 KSYK â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9342235 16189514 9169439
LCP2 KSYK â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 22267732 16189514 15388330
MK08 P85A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 7642542 16982329 25284480
SOCS1 P85A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25814554 10022833 29991678
DOK1 P85A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11071635 22974441
SOS1 P85A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25241761 17474147 10025673
IRS4 P85A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 25036637 18165436 11912194
P85A IL1R1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9360994 10373529 7499252
PTN11 FYN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11157475 16189514 16713569 10212213
PTN11 CBL â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 18519587 17330819 11157475
ERBB2 PTN6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 22973453 28065597
PTN6 BCR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9211920 9788431 27432908
LCP2 WASP â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10747096 16189514
INSR KHDR1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11604231 10437794
PGFRB EGFR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9506992 7531698 16713569
SHC1 PGFRB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 16713569 8195171
BCR 1433G â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29100370 28514442 33961781 16045749
1433G CBL â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11697890 28514442 15324660 33961781
FGFR1 CTNB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25241761 18302981 11401320
PK3CA AKT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19117013 21041639 25793261 21816939
HAVR2 LCK â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26492563 22863785
AKT1 IRS1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10497255 17640984
SRC CBL â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 5219404 17141222
CBLB SHC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9614102 16189514
CSF1R SOS1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 7520523 10025673
LCK CTLA4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9712716 9973379
SHC1 DOK1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10822173 11071635 22974441
SOCS1 IGF1R â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32700452 9727029 29991678
SOCS1 INSR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11342531 15169905 29991678
IRS2 SOCS1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12228220 29991678 27507812
RET SHC1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CRKL WASP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11313252
KSYK SRC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 7513017 9389695 16189514 15173175
KSYK GRB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22267732 10747947 16189514 11964172
KSYK CBLB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12771181 16189514 10022120 27428901
MET P85A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 7513258 24728074
CBLB P85A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19190244 10022120 9614102 11526404 10086340
CD3E P85A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19190244 11855827 9312149 11689561
P85A BCR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8781408 16219545 18346204
P85A CSF1R â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8947469 25241761 10025673
SHIP1 PTN11 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9110989 11453982 11157475
PTN11 EPOR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8639815 7534299
INSR PTN6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12468540 7512963 8114715 8692915
ABL1 PTN6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8114715 10574931 7512963 8692915 12468540 10488096
FAK1 ERBB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11807823 12600989 25241761 16713569 21034468
KHDR1 CRK â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 1545818 7537265 11278465
CBL PK3CA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9119889 8641358 19380743 11157475
CRK BCR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19380743 8978305 8943292
SRC DOK1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11071635 22974441
SRC GRB10 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10871840 32814053 33961781
SRC GRB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12624098 9016807 16713569 16189514 11964172
SOCS1 IRS1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12228220 11208867 17276034 29991678
KIT JAK2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 7527392 9355737 8611693
LCK LCP2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10556826 16354835 8702662 21725281
ERBB2 GRB2 â—¼   RELOCALIZATION ✅ + 0.85 0.85 Signor 14967450
IGF1R INSR â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
IGF1R IRS1 â—¼   PHOSPHORYLATION ✅ + 0.85 0.85 Signor 17827393
P85B CRKL â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11553620 9092574
CSF2R P85A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17474147 12538575
1433G P85A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15324660 17353931
AKT1 P85A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16007092 19117013 10527852 28205554 28628118
TLR3 P85A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16858407 15502848
LTK P85A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9223670 8084603
P85A CD19 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 7684160 15187135 7528218
P85A CAF1A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 17474147
SHIP1 SH3K1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22815893 15090612
SH3K1 CRK â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 11071869
GRB2 P55G â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32296183 21706016
CRK P55G â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25814554 19380743
VAV CD19 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15187135 7528218 16289966
AKT1 DP13A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29523594 25814554 25241761 12621049
PK3CA EGFR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31959764 25754235 8561895 28628118 28205554 1845983
KIT ABL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24728074 12374739
ABL1 ERBB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22973453 16273093 19275932
MET CBL â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 6538879 18273061
MET CBL â—¼   UBIQUITINATION ✅ 0.86 0.86 mint 11894096 5215187
SOCS1 EGFR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22973453 12070153 29991678
IRS4 GRB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9553137 21706016
SOCS1 KIT â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10022833 29991678
CBL ERBB2 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
CRKL PTN11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9344843 9660791 23397142
GAB1 LCK â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24728074 34079125
GHR P85A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9632636 17474147
FGFR1 P85A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15117958 25241761 18412956 8321198
P85A IGF1R â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 8697095 25241761 7589433 8603569 7642582
FAK1 P55G â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25814554 22402981 32296183
EGFR SH3K1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12177062 12771190 16849543 15456872 33643898 12218189 11894095 12734385 21635887
SRC RASH â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30194290 12695509 30639242
PK3CD P55G â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 32296183
ABL1 CTNB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23950177 17318191
VAV JAK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9162069 7530656
ERBB3 PK3CA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11546794 24189400 19411071
BCR RAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31871319 9535855
CRK CBLB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 25814554 19380743
MET CRK â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24728074 24828152
CRK SOCS1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25814554 10022833
GHR GRB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9632636 17474147
GRB10 IRS1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 8621530 12783867
SOCS1 GRB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10022833 29991678
SRC KIT â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24728074 12444928 12878163
SOCS1 MET â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24728074 25728680
CD28 GRB2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CRK SRC â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
GAB1 MET â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
IRS1 JAK2 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
SHC1 SRC â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
CBLB CRKL â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25814554 10022120
CRKL KIT â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11071635 9092574
P85B PK3CD â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19380743 9113989
P85B FYN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 1334406 16713569
TGFR2 P85B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 26186194 9435577
KSYK PTN6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10072516 11356834 10871605 34362877 10747947 16189514
VGFR1 P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20805333 23397142 7657594
ARAF P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11812000 10967104
LCP2 P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21282515 15929943 15388330
FAK1 P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11119718 10973983 10806474 8649427 16713569 7537275 19889638 11104793
NTRK1 P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25921289 8384556 8226808
UFO P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18346204 9178760
HAVR2 P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 26492563
CRK P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25241761 10962563 12878163 11418612 25814554 19380743
P85A FCG2A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8631888 9268059
P85A TGFR2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 26186194 9435577
FAK1 PTN11 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10082579 7589239 10655584 20473329 8986614 21726809 16189514
GHR PTN11 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10976913 9632636 9442080
PTN11 SOS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9344843 9632781 20473329 16371368
PTN11 MET â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18579758 24728074 8662733
IRS1 KHDR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11604231 8175658 22005517
P55G IRS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10417350 25814554 9415396 7542745
IRS2 P55G â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 10417350
P55G ERBB3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22973453 16273093 24189400
EPOR SHIP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15644415 10660611
FYN CTNB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12640114 25241761
SOCS1 VAV â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10022833 10747851 29991678
GRB10 ABL1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9006901 9747873
LCP2 CBL â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9716598 10204582 19635790 10477741
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
CSF1R FYN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 7681396 16713569
JAK2 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24240702 23838182 9363897 10358079 10635327 16273093
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
JAK2 FYN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10551884 16713569
SOCS1 FYN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10022833 16713569 29991678
NISCH IRS4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25036637 11912194
KIT LCK â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9788619 24728074
SRC RET â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 32062451 10070972 16189514
CRKL EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CRK EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
BCR GRB2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CRKL GAB1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ABL1 DOK1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CSF1R GRB2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
GRB10 INSR â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ABL1 GRB2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
IGF1R SHC1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CBL LCK â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
EGFR MET â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
GRB10 IGF1R â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CBL SHC1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
GRB2 KIT â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
GRB2 LCP2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
EGFR CRKL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18271526 24658140 31980649 16729043 23397142 25754235 25402006
GAB2 CRKL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9660791 10871282 11334882
CRKL BCR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10194128 15143164 9747873 8978305
GAB1 CRK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12138161 19380743 16713569 24728074
P85B GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20936779 8662998 19380743 21706016
P85B PK3CA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14681455 22402981 25253337 26496610 27684187 23604317 19380743
P85B CRK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25814554 19380743 31980649
P85B KIT â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7537096 24728074 10022833
P85B PK3CB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 22402981 26186194 28514442 19380743 32707033
CD3E KSYK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7761456 9698567
KSYK FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9535867 16189514 16713569
WASP P85A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10358777 8805332 16713569 17242350
LCK P85A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8246987 7504174 9461588 8294442 34079125
VAV P85A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17050525 9891995 9162069 16713569
PTN11 P85A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9918857 11593409 10962556 9361008 9660791 26839216 8647120 9632795 9565634 9886492 16371368
PTN6 P85A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11160222 9452499 11337495 10488096
RAC1 P85A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8034624 31871319 32814053 7629060 12086876 26475863 25284480
SRC P85A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19903481 23065768 32814053 23397142 10487518 25241761 24498420 19861161 16230374 12210743 16713569 7499252 12393736
ADA12 P85A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11313349 25825872
P85A FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8394019 8294442 7520528 16713569 25416956
P85A JAK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8702385 16135792 17474147 10026141
P85A ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17043237 23065768 11689445 11029009 16713569
LCP2 PTN6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15588985 9765283 16189514 8760799
PTN6 JAK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8943354 10772872
KHDR1 LCK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7852312 16888650 9045636 11278465 16107303 16274251
EGFR MK08 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
PGFRB CRK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10733900 16189514 16713569
PGFRB SRC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17158602 17785434 7685273 18315570 7678051 2173144 16189514
ABL1 1433G â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 25852190 15696159 16888623 28514442 30021884
1433G IGF1R â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15324660 27684187 17353931
P55G EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24658140 31980649 22973453 25241761 25402006 16273093
UFO EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27775700 35022314 25873175
UFO GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18346204 16189514 9178760
CBLB VAV â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9399639 11857085 16189514
VAV ABL1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11790798 19234221
IRS1 PK3CA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12933652 27684187 23643389 23604317 16354680 16150444 14511371
PK3CA LCK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8246987 8020561 14583609
NTRK1 ABL1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10679771 10708759
EGFR AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
RET CRK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9393871 10208419 32062451 25241761
EGFR DOK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
EGFR LCP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
EGFR LAT â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
EPOR GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9129019 7534299 8647802 16713569
SRC FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16966330 31980649 28514442 19711372 9169421
GRB10 RET â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7665556 28794017
RET GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7665556 10995764 15677445 9393871 8183561 32062451 16189514
NTRK1 GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10748052 11733534 25921289
INSR SHC1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
SHC1 MET â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7731718 24728074 9660480
EGFR GAB1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
ERBB2 SRC â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ABL1 CRKL â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
DOK1 CRKL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9822717 11071635 25814554 11553620
CRKL P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16982329 23397142 32203420 11418612 16135792 9461587
CRKL ABL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 8524328 16955467 8978305 19823681 16443220 7926767 7493940 18835194 9710592 24412932 14604282 22286129 9820532
EPOR GAB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15644415 12506011 10455108
JAK2 GAB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15644415 12506011 10455108
GAB1 IRS2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15644415 12506011 10455108
ERBB3 P85B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16273093 16729043 22973453 24189400
P85B ERBB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22973453 16729043 16273093 1334406
EGFR P85B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19531499 31959764 24658140 31980649 22973453 23956138 11172806 1334406 25402006 16273093
KSYK LCK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8798676 8621719 15536084 16189514 8798764 7539035
KSYK FCG2A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9295288 9280292 7487883 8756631 9268059 11141335
KSYK VAV â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11262396 11331248 8900182 8986718 16189514
IRS2 P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12107746 9334184 15514089 26496610 8910607 19561084 12506011 23439647 11438664 9852124 21241768
PGFRB P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11710529 7531698 9153411 8382612 11896612 1330535 16135792 8670861 7486683 19864249 16713569 15377662 7692233 8388538 10752619 1314164 8564419 10697503 7536927 28514442 7680644 1372092 7678051
CD7 P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12594831 8918688
SH3K1 P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15476827 11071869 20457601 17474147 10921882
SHC1 P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7537361 19889638 9541596 23397142 8621719 16713569 8662998 19380743 16219545 16135792
CBL P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9918857 19190244 17237826 7544353 10358153 8662998 9259313 8621719 14530346 15581361 7642581 15556646 9890943 16219545 10918571 8995243 16135792 9414268 8702998 8612729 19861161 16713569 11157475 19380743 11042121 16289966 9234717 16982329 8896416 9178909 33512474 8941725 11944898 25814554 9541596 9890970 9461587 9160881 7791764 9174058 8695807 24113870 11133830 11087752 18374639 9092538 10025673 9988765 11418612 15107835 21203488 11994282 10620516 11030146
ABL1 P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8781408 8294442 16219545 16135792 19380743 17474147 1383690
RASH P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10212255 9150145 25241761 16713569
CD28 P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19190244 7584133 24475931 7568038 11526404 7957566 8146197 7807015 7509360 9417079 18641334 9820515 7737275 8183372 27927989 8621607 10820259 8164687 17242350
LAT P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11368773 10811803 7544353 16713569
P85A CDC42 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8034624 31871319 7629060 9381982 25284480
P85A EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19531499 21701776 7531698 31959764 22973453 8662998 25241761 16230374 7797556 25754235 25187647 16713569 7499252 16273093
P85A KIT â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17452978 10022833 1382595 7509796 25241761 12878163 24728074 16713569 9233773 7537096 11071635
ERBB2 PTN11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22973453 16729043 28065597 9756944 8959326 16273093
PTN11 KIT â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24728074 7523381 9528781 12444928
PTN11 INSR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9593725 8895367 7493946 8135823
PTN11 IGF1R â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10082579 8895367 28065597 7642582
PTN11 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12270932 11223155 20473329 16729043 22973453 7673163 28065597 24935154 9756944 14560030 7588774 8959326 16273093
PTN6 KIT â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9528781 7684496 12614164
PTN6 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9733788 22973453 28065597 7673163 25187647
PTN6 LCK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8114715 11294838 10617656 19167335 10574931 7512963 8692915 12468540 16189514 10488096
CDC42 WASP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25502805 10360578 10802735 15361624 8643625 9660763 10684602 10360579 9422512 20936779 10068673 8625410 9742969 12769846 16189514 10713100 12235133 28539360 22252508 10724160 15075243
CRK FAK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7529876 10085298 7509446 12370821 12615911 7561682 25814554 11314030
FAK1 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15657067 24658140 31980649 20473329 10806474 25402006 16713569
MK08 CRK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25241761 11432831 16982329 16713569
MK08 IRS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10722755 11606564 12417588 12351658
CBLB SH3K1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12829691 12874286 23663663 12177062 19531213 32296183 12218189 18680311 16228008 17020880 16189514 19268472
PGFRB GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7486683 7935391 9362449 16713569 10026169 16189514
1433G IRS2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 28514442 15324660 17353931
1433G ARAF â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15324660 31980649 17353931 25852190 28205554 28628118 28514442 32707033 29777862
P55G IGF1R â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9524259 25241761 17360667 9415396
EGFR CTNB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11950845 9535896 24189400 9233779
ERBB2 CTNB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11245482 11950845 7702605
CBL VAV â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16356860 11331248 12881521 11133830 9200440 16713569 18835194 19635790 16289966
LCP2 VAV â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9341187 11331248 8703037 10347175 8673706 19635790 21725281 16189514 9047237
LAT VAV â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11368773 12186560 17306257 16713569
VAV EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 22973453 10938113 25402006 16273093
SRC ABL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11494128 12522270 11781820 17318191 17474147
GRB10 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9006901 23331499 9747873
SRC CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22203672 29899407 17141222 18996392 12941616 15135048 18273061 10829062 31120930 19861161 7782294 16713569 8635998 11994282 17094785 16636290
EGFR CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23158001 24797263 25872741 31182136 10635327 26055326 14505571 15210722 32714745 23774213 19155296 11370743 19836242 8665853 19947936 18271526 25140053 15668240 22394513 17486068 33323455 32377695 22203672 17182860 12604776 14627991 15383614 23153581 15735736 28541302 16849543 17242169 20562913 32904620 9121472 15677445 7782294 16923119 17995934 19531499 15465819 31959764 32114396 23457600 29629558 18316398 23799367 24714105 31120930 12061819 16713569 7657591 33617900 10086340 19225046 33762435 23175185 16729043 28791635 16246327 28198003 15962011 22266821 15117950 27059931 10428778 12734385 8662998 25005938 27903975 16969069 26177020 8798643 10799548 9756944 15159412 19578043 15657067 18255265 23418353 25754235 22976291 17545148 12803489 18319245 19713535 7592693 30544639 15107835 11994282 17971399 16105874 15282549 20940296 23897813 9130710 18273061 18508924 17880946 20124286 12593795 16914641 20877636 10092522 25521828 11408594 22591401 9890970 20308550 22833562 21772844 33627783 11239464
IRS1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10854852 19546233
CBL IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18632619 17635922 10514377
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
IRS4 CRK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11316748 9614078 16713569
EGFR CRK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10595738 9480911 9642287 24658140 31980649 11956190 16729043 22973453 8875975 25402006 9617486 16273093 12198159
ERBB3 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23436906 10527633 27756321 21278786 18803307 17148612 22439932 25315821 10572067 24189400 23866081
GRB10 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9006901 31980649 24658140 9506989 25402006
EPOR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8647802 16713569 7534299
SRC ERBB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22973453 19704002 21075308 7542762 7797556 19372587 29720121 11940572 17875712
SHC1 ERBB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 30898150 10085134 9019162 24658140 22973453 16729043 9710588 28065597 16843263 9756944 16713569 16273093 8665853
SHC1 ERBB3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11546794 9019162 24658140 22973453 16729043 24189400 9756944 9694850 16273093 16189514 8665853
SHC1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20935677 11773443 16713569
SRC ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17043237 17284441 17400812 15604093 11032808 17921256 18451880 15020686 12736255 11564893 23065768 10454579 20935677 17363140 16957778 14963108 11013076 29720121 15784253 24498420 17627277 12630920 22328528 14766010 24051437 7539106 27420286 15140878
ESR1 RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21737465 21947652 22878616
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
FYN LAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16938345
LCK GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11572860
LAT GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10811803 23460737 7544353 9489702 12359715 12186560 16938345 16713569 16906159 8063801 11368773 16189514
KIT GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17452978 10022833 17904548 12444928 7523381 10377264 24728074 16713569 8950973 7523859 8647802
JAK2 GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8536716 17474147 8950973 7500025
MET GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9660480 11439336 8662889 19433454 15546961 11063574 7511210 21222362
IRS2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19109239 7890616 9535722
IRS4 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9553137 15316024
SOCS1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12228220 17276034 11208867
LTK IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9223670
KIT SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8950973 16129412 10377264
LCK LAT â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12186560 14523017 16938345 12359715
SOS1 LCP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11390650 10021361 10224278
SRC MET â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24728074 9837958 20624308 24034250
SHC1 RET â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15677445 8183561 9047384 32062451 16189514 28213521
EGFR SOS1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
GRB2 SOS1 â—¼   RELOCALIZATION ✅ + 0.9 0.9 Signor 23452850
ABL1 CBL â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
CBL MET â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
JAK2 SOCS1 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
BRD7 P85A â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 24657164 30940648
PK3CD RASH â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 9235916 10922060 22020336 9113989 11739523
SRC ADA12 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 25825872 11127814
1433G IRS1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 30240640 28514442 15324660 33961781
DOK1 RET â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
SHC1 SOS1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
GRB2 IRS1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
ERBB3 SHC1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ERBB2 ERBB3 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
INSR IRS1 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 7651388
ERBB3 PTN11 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 22973453 9756944 28065597
PTN6 VAV â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 8632004 16189514
RAC1 WASP â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 8643625 16189514
FAK1 SHC1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 11980671 16189514 16713569
GRB2 BCR â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5214841 11726515
FYN CTLA4 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 9712716 9973379 25241761 16713569
GRB2 ERBB2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 16273093 5218056
GHR SHC1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 9632636 7535773
SHC1 JAK2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 7535773 9126968
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
ERBB2 SHC1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
INSR IRS1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
CBL FYN â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
PTN6 PGFRB â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 19167335 9452499
CBL VGFR1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 18273061 25387128
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CBL SRC â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
P85A KSYK â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 15536084 16921024
P85A CTNB1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 10477752 25241761 11716761
SHIP1 SHC1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 10194451 15470047 8874179 11453982 8723348 12024011 10704825 10900203 10822173 8643691 12149229
ERBB3 GRB2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
MET GAB1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 9242692 10871282 10995442 10734310 10913131
P85A ERBB2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 7531698 22973453 16843263 21075308 9756944 12896906 16273093 1351056
RASH PK3CA â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 24412244 9150145 10783161 14724584 8665852
SHIP1 GRB2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 11453982 8723348 9108392 10900203 22267732 12149229
SRC CTNB1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 23246962 11279024 22056988
VAV FYN â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 9822663 11262396 16189514 16713569
VAV CDC42 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 18511940 11287617 16189514 32203420
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
SOS1 FYN â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 17474147 16713569 9856337
JAK2 IRS1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 15316008 11208867 9492017 12960006
CBLB EGFR â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
ERBB2 GRB2 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
CBLB GRB2 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
GAB1 CRKL â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 30480076 10753869 23397142 25241761 24728074 10871282
CRKL EPOR â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 9344843 9129019 11443118
P85B CBL â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 19190244 11133830 15107835 25814554 19380743 7629144
GAB2 P85A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 16253990 10871282 14530346 9660791 12506011 26839216 11334882 11782427 16135792 10068651 16219545
INSR P85A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10500481 11796522 8385099 7589433 1334490 8567177 7659087 8276809 9593725 14729945 15629149
P85A EPOR â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 9162069 7559499 12506011 15644415 16713569 24113870
PTN11 JAK2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 8912646 9442080 7559603 8639815 8995399
PTN11 GAB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 12135708 14982882 11287610 11812650 16253990 19172738 15356145 15170389 9660791 26839216 19909739 10391903 11782427 11334882 10068651 10871282 16371368
PTN6 GRB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 8632004 10660620 25535246 10747947 16189514 11964172
PTN6 EPOR â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 7889566 7528537 7528577 7228577
WASP GRB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10224664 8805332 16713569 8892607 16189514 9307968
WASP SRC â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 8805332 16713569 16189514 8824280
GRB2 SH3K1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 31980649 16713569 11152963 16189514 10921882
P55G PK3CB â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 28514442 25814554 22402981
P55G PK3CA â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 14681455 33961781 22402981 26496610 9415396 28514442 25814554
DOK1 SHIP1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10822173 11071635 15151996
VAV RAC1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 18511940 11287617 32203420 16397238
SHC1 CBL â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 9234717 9541596 15677445 8621719 16713569 8950973 10025673 10570290 8662998 19380743 9461587 9434624
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
SOCS1 CSF1R â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 11297560 10022833 29991678
SOS1 EGFR â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 19531499 18271526 31959764 24797263 7510700 20473329 19289468 10675333 23956138 25754235 8621459 16713569 26005835 9447973
JAK2 EPOR â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 14982882 12441334 8343951 11779507
SOCS1 JAK2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 11971965 18508766 19287004 9344848 10421843 14517242 11314018 29991678 10064597 11713228 29674694 9202126 14522994 10455112 28258213
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
PTN11 GAB1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9658397 15574420 9804835 23612964 10068651 14982882 14701753 11453982 12855672 14665621 11323411 20473329 24935154 24728074 20308328 9632795 11134009 10871282 11940581
GAB1 P85A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 16638574 10978177 9658397 8596638 9804835 11940581 24728074 9891995 12506011 23612964 9632795 11606067
TGFR2 TGFR1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 8576253 10026191 19556242 11483955 21791611 23868260 7890683 21423151 25825445 11102446 7878020 19758997
KSYK CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11742985 12435267 10617633 11331248 11133830 7721825 8621719 18273061 10570266 15536084 16289966 31120930 10540342 9857068 15556646 11042121 27614019 15577829
ERBB3 P85A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 15812817 11546794 20227043 21278786 11389077 22973453 10383151 9130710 24189400 21075308 9756944 12896906 18803287 22439932 11694521 10572067 16273093 20007781
PK3CB P85A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 27107012 24657164 26344197 32814053 22939629 25241761 26496610 8139559 26839216 21825134 10358930 32707033 20713702
PK3CD P85A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 32296183 18641334 21827948 26496610 31031754 24165795 22020336 9113989
KHDR1 P85A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11604231 10467411 8175658 22745667 7537265 16713569 10437794
P85A GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7544353 8621719 18346204 7642581 16219545 32814053 7642542 20936779 16713569 19380743 21706016 7759531 8647120 25416956 9541596 9174058 11418612 7737969 9886492
P85A PK3CA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22402981 20018188 26496610 23643389 26475863 26839216 11526404 16135792 32814053 27684187 7957566 15932879 28628118 16043515 20713702 15377662 9235916 25253337 19805105 19574958 33420362 7929193 24657164 19117013 28205554 9565634 18079394
PTN11 GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 8702859 33961781 12531430 34407391 10747947 9824671 12577067 9361008 9660791 19380743 7534299 8995399 16371368 10080542 21706016 20473329 7523381 8041791 9362449 10212213 8647120 28514442 16189514 9632781 31980649 9254654 8959326
WASP FYN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7565724 10224664 16189514 8805332 14707117 16713569 12431372 10532312
FAK1 GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10085298 7597091 20473329 7997267 10806474 21900206 8649427 12558988 12005431 16713569 8816475 16189514
FAK1 FYN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11278857 31413325 12558988 16713569 32707033
SRC FAK1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11927607 22402981 7997267 12387730 12558988 23242524 26264872 8941336 16291744 15987550 32814053 9822703 16713569 9507031 17525734 21855630 7529876 11119718 16966330 23065768 8816475 25814554 16189514 11104793 10085298 10931187 8054685 25241761 12615911 21034468 11980671
KHDR1 GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10467411 8576157 21706016 12112020 7799925 9045636 11278465 9872323 22745667 20936779 11960376 7537265 16713569 21988832
KHDR1 FYN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 31980649 14647465 16888650 9045636 22745667 31413325 11960376 16713569 7516469 15190072
SH3K1 CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 17675467 25036637 33961781 12177062 25005938 19417776 15090612 11894096 14596919 19268472 17306257 15456872 20130058 16713569 16407834 19531213 17072306 22262777 20711168 11894095 11152963 15962011 16228008 24167568 28514442 10679202 12135478 29589748 25472714 12874286 22833562 21830225 31980649 33627783 11071869 12618476 15107835
RASH SOS1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9690470 20133692 12628188 34407391 15507210 16713569 11560935 18454158 19141281 26721396 9447984 17084389
VAV GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 15558030 18692475 7809090 32203420 8900182 29997244 16339550 16713569 8647120 16189514 10207103 9013873
DOK1 ABL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9822717 19823681 22974441 10688886 10567556 11071635 9008161
FYN CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9677430 8621719 12244174 7782294 10629042 119942 7642581 15556646 12231245 9311917 9535867 8626543 10799548 16713569 16503409 10092522 8900205 8995358 25814554 9890970 15190072 15208330 12941616 10829062 11239464 8662998 17094785
SOS1 CRK â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 8810325 33961781 8943292 31980649 25241761 32203420 19380743 17474147
SHC1 EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10595738 24797263 24658140 7542744 21278788 9130710 28065597 10766863 10635327 8034616 24430869 7518560 12577067 19531499 31959764 8810340 9742218 11196191 23799367 23956138 9756944 16713569 11370743 8665853 18271526 15657067 11408594 20473329 22973453 16729043 20935677 20067773 7506413 16273093 25754235 8610109 24189400 26551075 9388490 8887653 31980649 7542991 9544989 9020193 25187647 25402006 30544639 10049786 8662998
SRC EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22227249 17284441 24658140 17158602 21278788 20333651 28065597 7527393 7797556 10777553 16713569 20624308 23175185 7506422 22973453 20935677 24189400 11983694 10075741 31980649 19704002 10358079 10971656 21268077 9020193 25402006 21573184 8845374
ERBB3 ERBB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22806884 25898135 30523157 9130710 21278786 15812817 20227043 16843263 10572067 19411071 19060928 8665853 10799311 8816440 17426253 17148612 21075308 12896906 15504738 23680147 23688700 23866081 22733765 7592681 21203579 25326665 24557338 23436906 30898150 7538656 25241761 25315821 11173924
LCP2 GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10224278 8695800 32296183 19380743 9565634 11314042 7706237 20936779 12176364 10204582 8995445 25416956 9716598 15929943 17235283
IRS1 GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 8810325 21706016 7486683 8536716 8388384 8491186 22974441 12173038 7488107 7629070
SRC SHC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9388490 18840094 9710204 10482988 9096689 7499252 8939605 26551075 16189514
EGFR ERBB3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
NTRK1 SHC1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
EPOR JAK2 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
ABL1 CRK â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GAB2 GRB2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
IGF1R IRS1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
P85A IRS1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 8382612 8175658 7680095 17640984 23643389 16230374 26839216 7659087 9564850 14511371 12220227 7486683 1381348 15514089 22974441 12730242 16043515 16150444 16354680 16880210 12107746 30240640 33991522 19561084 8628286 14632132 25814554 7935461 7680644 8388384 29526746 11416002 1334490 23439647 12173038 25273559 11403293
PTN11 IRS1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 11781100 8505282 7935386 9535915 22974441 9756938 7513703
PTN11 PGFRB â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 23922991 11266449 8119896 23397142 8041791 8538796 7530043 7688466 12681492 12614164 8183548 16189514 7691811
KHDR1 SRC â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 10467411 18606683 1545818 22745667 1374686 8766817 9038356 16169070 7537265 11960376 16713569 10635328 15190072
ARAF RASH â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 24441586 12620389 28205554 28628118 10545207
SHC1 GRB2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 12213123 8491186 8950973 9927207 9733714 8112292 10356320 11370743 32062451 8294403 16371368 22057045 9045692 9032244 8995379 7514169 9175774 9541596 8663178 7629070 9019162 7597091 7798267 9544989 9488479 8940013 10570290 15812354 11792427 8621719 24430869 7650032 11453982 16713569 7516467 10477741 8662733 11302736 26551075 9254595 7559490 12441060 8662998 8235613 12485888 28690151 16520382 8939605 11505033 9129019 11707405 15888547 8647288 7524086 25416956 24189400 11827484 12149229 8195171 21725358 9020193 10049786 9797459 9886492 33961781 9126968 8626525 7537740 12577067 11964172 12898421 8810340 22974441 19380743 9434624 10080542 9083103 21706016 15688026 7535773 31980649 8561895 7744881
GAB1 GRB2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CBL CRKL â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL CRK â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EGFR SHC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GRB2 SOS1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MET CRKL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10871282 12138161 11146548 10753869 10618718
CRK CRKL â—¼   PHYSICAL_INTERACTION 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
GRB2 CRKL â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
SHC1 CRKL â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
CRKL CBL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
GRB2 CRKL â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
SHC1 CRKL â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
CRK CRKL â—¼   SHARES_COMPLEX 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
CRKL CBL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
FYN CRKL â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10591186 10648627 11062502 12218089 12731048 15536084 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
CRK CRKL â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
ABL1 CRKL â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
CRKL CBL â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
GAB1 CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10753869 25241761 24728074 31585087 10871282 10592173 23397142
BCR CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26500649 8978305 15143164
EGFR CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 31980649 23397142 18271526 24658140 25402006 16729043
ABL1 CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 8978305 22581121 20841568 10837221 18768933 7493940 9710592 16955467 8524328 23331499 21199784 18794134 10592173 21051857 7926767 16443220 18835194 24165979 26500649 18809728 15459660 26192618 24412932 9053848 22286129 8083188 14604282 21435002 9820532 19823681
CRKL GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10753869 25241761 24728074 31585087 10871282 10592173 23397142
GRB2 GAB1 â—¼   PHYSICAL_INTERACTION 50.0 1.0 ACSN 10086337 10514377 10567412 10648629 10811803 10982827 11062502 11313945 11385609 11447289 11777939 11907067 11940581 12040186 12175651 12419216 12640133 12670391 12782630 14585353 15199124 15534002 15536084 15567848 15574420 15584861 15863030 16102570 16227978 16488589 16582911 16847462 16887996 17496910 17635922 17673906 18287025 19449109 19568798 19615955 20805416 21102635 23523669 24027568 26552706 27111285 7510700 8294866 8551221 9779982
GRB2 GAB1 â—¼   SHARES_COMPLEX 50.0 1.0 ACSN 10086337 10514377 10567412 10648629 10811803 10982827 11062502 11313945 11385609 11447289 11777939 11907067 11940581 12040186 12175651 12419216 12640133 12670391 12782630 14585353 15199124 15534002 15536084 15567848 15574420 15584861 15863030 16102570 16227978 16488589 16582911 16847462 16887996 17496910 17635922 17673906 18287025 19449109 19568798 19615955 20805416 21102635 23523669 24027568 26552706 27111285 7510700 8294866 8551221 9779982
GRB2 GAB1 â—¼   ENZYMATIC_REACTION ✅ 50.0 1.0 ACSN 10086337 10514377 10567412 10648629 10811803 10982827 11062502 11313945 11385609 11447289 11777939 11907067 11940581 12040186 12175651 12419216 12640133 12670391 12782630 14585353 15199124 15534002 15536084 15567848 15574420 15584861 15863030 16102570 16227978 16488589 16582911 16847462 16887996 17496910 17635922 17673906 18287025 19449109 19568798 19615955 20805416 21102635 23523669 24027568 26552706 27111285 7510700 8294866 8551221 9779982
MET GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 10978177 17389395 19901323 10753869 15574420 15212693 10913131 10734310 11896055 20068231 10995442 9890893 16497976 14685170 17016520 18669648 11779868
CRK GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 24728074 20619534 12138161 19380743 11146548 10592173 19350053 16713569 10618718
INSR GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 10753869 10978177 17389395 19881549 10734310 20068231 9890893 9658397 16497976 26929352 17016520 18669648 11323411
EGFR GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 19901323 15231819 16497976 25402006 17389395 20068231 23066441 11432805 9658397 19509291 18669648 10978177 10753869 10734310 11896055 18271526 24658140 10648629 11779868 31980649 15212693 9890893 17016520
GRB2 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 12766170 21706016 9242692 10913131 11445578 22536782 8596638 11027663 10592173 20936779 11960376 15010462 19523899 20005866 19380743 10871282 9804835 14685170 11314042
SHC1 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11707404 14982882 24728074 10871282 10194437 9804835 12808090
SRC GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26706435 15574420 19881549 12941962 21442024 12808090
ABL1 CBL â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
ABL1 CRK â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
NTRK1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 10708759 10679771
LCK ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16076903 16787943 17570479 11847100
FYN ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12522270 16787943 17570479 16912036 16076903 17474147 11847100
SRC ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 19901323 10964922 16497976 20841568 16787943 17570479 17318191 11847100 10500097 12522270 18691976 11494128 11781820 16076903 20168609 12748290 16464493 12445832 19369195 17474147
ABL1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 9525940 11494134 16713569 20841568 10829062 17389395 16955467 12604776 9890970 10391678 9195915 14725908 7925293 11997497 12522270 15556646 9102067 11239464 11994282 9174058 12475393 20675402 19380743 14604282 8626543 15212693 19823681
ABL1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12560071 20841568
ABL1 DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11071635 10567556 12777393 9008161 15148308 15592455 25043303 18768933
ABL1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 11726515 16713569 20841568 8596638 16955467 10592173 8647802 8194526 7926767 14725908 23950177 8112292 9407116 23181695 19380743 17474147 9516488 19823681
ABL1 BCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9407116 10405761 12522270 11780146 8622703 9178913 1712671 12124177 7529874 9467953 8955135 20841568 8112292 16912036 12543778 11376433
ABL1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8617726 1623525 10194451 19380743 10592173 20841568 8112292
ABL1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20841568 20101225 30692633
ABL1 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 9826708 12766170 9391119 9242692 10506185 8547236 10069803 7687741 10490849 11741535 21777671 8906793 12475979 9444958 7513258 7961992 15475459 9252406 7838524 7731718 8662889 7708691
ABL1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15039778 20841568 8112292
ABL1 CD19 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11120811 20841568
ABL1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 24430869 15192046 33889303 16273093 16943190 14760089 29880877 15618223 33574089 8910327 12631709 25173817 25402006 20841568 33947961 34107301 34469737 19915609 32019812 2022651 34290403 33707748 15329413 7678409 9733788 8490966 28338646 3263271 15901825 2022652 10069801 7506413 24658140 8408058 34385595 31980649 1314835 7741752 18668345 28724430 12648464 25073158 26079946 34155348
ABL1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16705159 15923602 15793561 25821558 9111318 15143187 16705160 11593427 20841568
ABL1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 100.0 1.0 Omnipath 8978305 9747873 9480991 19426560 17081983 23124138 16522685 16713569 20841568 18768933 8875975 25860930 21779437 19534553 16187300 17515907 21602891 16267043 20068231 10592173 17570479 8194526 7926767 11080615 25381819 12198159 9642287 15696159 18619508 18835194 11956190 22848689 11314030 9480911 19001122 19402756 20697350 12384576 24412932 7542925 11380621 12799422 19380743 12955086 17474147 17016520
RAC1 AKT1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
GRB10 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11809791 15722337
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
RAC1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 18000759 20027184 21157483 11756412 11923280 16697215 20398329 17461779 18372248 20338997 15808505 20138985 20214616 21474067 19568798 15169778 19720745 18925875 10949026 11715018 19143635 12393431 18636226 10617634 9812896 17680028 19151919 10722653 20832730 18570873 17052453 12408816 11274345
RET AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12600984 15994200
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17570479 17640984 10497255
AKT1 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11782427
SRC ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9020159
GRB2 CBL â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 25036637 25872741 8950973 917890 7642581 17944804 15210722 9108392 20936779 8695851 19836242 14725908 169092 28514442 9541596 9174058 11823423 12941616 10829062 10570290 7544353 11792427 8083187 15677445 8621719 9233773 9311917 23799367 16713569 10086340 9234717 8995358 25814554 9716598 11997436 7791764 8943292 8063801 8995445 8662998 11263968 16906159 8626404 9129019 98621719 17072306 9242692 10521482 9872323 8647120 7592693 9092538 10025673 17971399 17094785 9851874 11399323 33961781 9259313 18273061 7537740 8649804 9295052 11964172 9367879 20124286 10204582 19380743 9434624 21706016 8900205 9178909 12839496 9461587 31980649 11133830 33627783 8824292 8621483
CRK CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRK CBL â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
LTK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 9223670
FYN CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 97.0 1.0 Omnipath 9525940 7642581 8626543 7782294 15208330 16503409 16713569 10829062 10799548 10934191 8900205 8551236 8662998 8995358 19734451 12604776 9890970 10592173 17570479 10629042 17094785 10092522 11997497 12522270 15556646 12244174 8621719 9102067 22880054 9311917 11239464 19904769 11994282 12941616 9535867 25814554 12231245 15190072
SRC CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 9525940 7782294 16713569 18273061 10829062 10799548 10934191 12604776 9890970 17570479 9013636 15135048 17094785 25784557 8635998 10092522 12522270 8621719 17141222 16636290 11239464 19861161 11994282 12941616 14739300 22203672 8849724 15212693
CRK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 8683103 16289966 8626543 8621483 9617486 16713569 9416834 8524328 10962563 8626404 9367879 8662998 12393469 11792427 15581361 9013636 15581362 9178909 9988765 18835194 8943292 20697350 9129019 19380743 25814554 9461587
LCK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 9525940 10829062 10799548 10934191 7721825 16107303 12604776 9890970 17570479 11904433 9178909 10092522 11997497 12522270 8621719 9102067 11239464 11994282 11741956
INSR CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 11997497 10635327 11994282 12522270 9525940 12604776 10592173 17570479 9102067 15951569 10829062 15212693 11239464
CBL CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11847211 10025673 10648820 11850825 7782294
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
CBL ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25102001 20332299 17635922 10514377
CBL MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 16397241 15123609 23331499 25241761 21222362 11894096 18672314 21163258 19450681 18273061 35309168 17533376 19433454 17635922 10514377
CBL KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 9092574 17904548 25737303 8950973 15315962 17635922 10514377
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CBL RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12727845 15677445
CBLB KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15315962 12177062 17635922 10514377
CBLB CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 8626404 19380743 12697763 25814554
CBLB EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17145710 19531499 11375397 10086340 12577067 10542134 17635922 10514377
CBLB SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19531499 11375397 16189514 9614102 12577067
CBLB FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15208330 16503409 32296183 25814554 8083187
CBLB GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 10022120 25416956 21706016 31467278 32814053 9614102 17635922 11375397 8626404 16189514 21900206 20936779 27107012 12577067 10514377 19531499 10086340 29997244
GRB2 CD28 â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 10086337 10209041 10567412 10811803 10982827 11447289 11777939 12175651 12640133 1313950 15197224 15567848 15574420 16582911 16887996 17496910 17673906 19449109 22437870 26552706 7523569 8551221 9359474
GRB2 CD28 â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 10086337 10209041 10567412 10811803 10982827 11447289 11777939 12175651 12640133 1313950 15197224 15567848 15574420 16582911 16887996 17496910 17673906 19449109 22437870 26552706 7523569 8551221 9359474
FYN CD28 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10591186 10648627 12218089 12731048 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
CD28 LCP2 â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 10086337 10209041 10567412 10811803 10982827 11447289 11777939 12175651 12640133 1313950 15197224 15567848 15574420 16582911 16887996 17496910 17673906 19449109 22437870 26552706 7523569 8551221 9359474
CTLA4 CD28 â—¼   DOWN_REGULATES ✅ - 12.0 1.0 ACSN 10921877 11093160 12370081 16227604 16885030 16916641 18292600 19890961 21159657 21376459 22116087 22437870
LCK CD28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7568038 22936936 27460989 16094384 10430626 8992971
CD28 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 18829987 8576157 9694876 24098653 27927989 21487479 7737275
LCK CD3E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12522270 2470098 15144186 11855827 15592455 16094384 15659558
SRC CDC42 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
SRC CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14506284 26816343 9626657
GRB2 CRK â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
SHC1 CRK â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
SHC1 CRK â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 CRK â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
NTRK1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7657647 8552402 12446789 7509449
IGF1R CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 12198159 9642287 9480991 9480911 20068231 11956190 8194526 8875975 15522217 17016520
EGFR CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 52.0 1.0 Omnipath 10595738 9480991 16273093 9617486 25402006 17399949 8662907 8875975 21602891 20068231 8194526 12198159 9642287 11956190 24658140 26656091 9480911 31980649 15212693 26473374 16729043 17016520
RET CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9393871 10208419 25241761
IRS1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9837978 8810325 8621590
CSF1R GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9178909 9380408 10025673 8262059
FYN CTLA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 9712716 25241761 9813138 9973379 16713569 10842319 10694513
JAK2 CTLA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10842319 9813138 9973379
LCK CTLA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9712716 9813138 9398332 9973379 10842319
INSR DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 9008160 19901323 15212693 19481264 19690332 16497976 15592455 16094384 10688886 16153436 11551902 12087092
SHC1 DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11071635
FYN DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11489946 16537894 11841937 11825908 15345598
RET DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 19901323 23331499 10688886 16497976 15592455 16094384 12087092 11551902 16153436
LCK DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16537894 10799545 11841937 11489946
KIT DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11071635 11825908
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
EGFR SHC1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
JAK2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17389395 10635327 17081983 10358079 16273093 16799092 18691976 10459005 9363897 15284024 23838182 17016520 18669648 15302935
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9544989 19531499 9447973 16713569 12577067
EGFR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 78.0 1.0 Omnipath 9544989 8808684 10595738 23956138 9388490 11350724 16273093 7542991 7681824 7518560 9710588 23799367 16713569 25402006 11370743 24797263 9742218 20935677 8887653 8034616 23331499 8662998 7542744 10049786 28065597 9130710 10635327 24189400 7506413 18271526 15657067 24658140 8810340 12577067 11196191 10766863 23178716 31980649 35384245 11408594 19531499 9756944 26551075 1623525 15951569 16729043 17956904
EGFR ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 23436906 7929151 21278786 24189400 23866081 17148612 12648464 27756321 18803307 10527633 10572067 22439932
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
JAK2 EPOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 10660611 12441334 7559499 8343951 18672044 11779507 12027890 11443118 12524467 9030561 9573010 15212693 10579919
ESR1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 24559156 16115928 16467118 17992604 19915977 15199112 21127199 21761336 21907803 20551150 11713584 1358436 20629094 18768663 19005469 9242384 20889718 10698518 16467117
ERBB2 ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 17145710 23680147 17148612 24557338 19411071 21203579 7592681 23688700 23331499 21278786 12648465 22806884 27531070 17570479 30898150 29066975 17426253 16843263 9130710 20227043 25241761 10799311 8816440 22733765 10572067 19060928 11173924 21075308 23436906 7538656 15504738
ERBB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 15173068
ERBB2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 31980649 9756944 21278786 16273093 24189400 11173924 9710588 24658140 11606575 14967450 17875712 16713569 16729043
ERBB2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16769082 19617202 11940572 12753909 21075308 7542762
ERBB2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 28065597 23331499 9756944 16273093 8026468 9710588 10085134 24658140 9590694 16713569 16729043 16843263
ERBB3 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 9694850 9756944 16273093 24189400 8026468 24658140 9590694 16189514 16729043
ERBB3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9756944 24189400 11173924 24658140 14967450 16729043
ESR1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17170218 20021813 16087727 19250214 10982795 24281069 18414489 15595626
LCK ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9500442 10571988 25386784 11145737 7539106 27748765
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
FGFR1 GRB2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
LCK FYN â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
SHC1 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
FYN GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 10871840 16713569
FYN LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10648627 9047237
FYN SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 96.0 1.0 Omnipath 19901323 20230923 16497976 9121430 15592455 16713569 9446569 17389395 23331499 18578522 10921922 10482988 10764799 18452278 20068231 10592173 18669648 12522270 9685404 10896916 7516469 9927207 12237775 8702728 8610109 19651622 9741627 9710204 19664994 17016520 10816433 11075717
FYN KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9038210 9799234 12374739
FYN SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17474147 16713569 9856337
GRB2 GAB2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10086337 10358164 10567412 10811803 10849428 10982827 11447289 11449354 11777939 12175651 12393695 12640133 15567848 15574420 16076871 16212621 16582911 16887996 17496910 17673906 19449109 19909365 26552706 8551221 9763606
SHC1 GAB2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10086337 10358164 10567412 10811803 10849428 10982827 11447289 11449354 11777939 12175651 12393695 12640133 15567848 15574420 16076871 16212621 16582911 16887996 17496910 17673906 19449109 19909365 26552706 8551221 9763606
GAB2 LCP2 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 10849428 10982827 11572860 12640133 16212621 19909365
GRB2 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17145710 16371368 25416956 21706016 15143164 10391903 19172738 10913131 11027663 9973481 10973965 20936779 10068651 11882361 32296183 16199887 24737791 15010462 19523899 16253990 19380743 31515488 11782427
SRC GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10391903 12464621 11640929 9885561
JAK2 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18644434 21183952
GAB2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8995358 10704825
GAB2 LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15286727 23109003 12640133 11323691
GHR JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8063815 23331499 10502458 17312100 21347402 18988627 7540178 9211920
KIT GRB10 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16129412 10377264 11809791 9872323 8647802
SRC GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10871840
RET GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 7665556 8631863
IGF1R GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19165858 8776723 8764099 8621530 12697834 9506989
INSR GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9506989 15664450 10871840 8621530 9006901 19648926 7479769 12783867 12493740
KIT GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11809791
SOS1 GRB2 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 8810325 33961781 8695800 7510700 8626525 34407391 16520382 10570290 16906159 16893902 7642581 8816480 9447984 12577067 11964172 8112292 8493579 7664271 16713569 7516467 19380743 9009162 10207103 17474147 10477741 32062451 7629138 21706016 20473329 19323566 9872323 32203420 7514169 21988832 28166272 28514442 9716598 11997436 9344843 15192046 10716926 8479541 14679214 8943292 31980649 7629168 7559490 9478994 7527391 8188688 11960376 10025673 11726515 7773779 10319320 9569023 9797459
GRB2 SHC1 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 RAC1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 LAT â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 RAC1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
IRS1 GRB2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10086337 10826997 12175651 12444011 12767520 16931767 17604717 19030972 21540285 22465479 24036369 8621421
LCK GRB2 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10652356 11062502 12731048 12740575 15536084 17544292 19290918 20814939 21127503 22513334 23620508 8478617 8986721 9438848 9738502 9751747
GRB2 LAT â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 SHC1 â—¼   ENZYMATIC_REACTION ✅ 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 LCP2 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
MET GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9660480 15546961 22128289 12475979 11063574 7511210 11439336 8662889
KIT GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 24728074 8950973 7523381 10022833 7523859 8647802 16713569 17452978 17904548 10377264
LAT GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 11368773 9489702 10811803 8063801 17043143 16938345 16713569 23150273 12186560 16906159
IRS1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 8265614 7862167 11788580 8388384 8491186 8536716 7488107 7486683 10358772 10592173 8196603 12173038 12679424 8114695 11259577 8810325
IRS2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7559579 11788580 10358772 11305324 9852124
JAK2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8536716 8950973 7500025 17474147 19273609
NTRK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733534 10748052
RET GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9393871 16189514 15677445
LCP2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 7706237 20936779 10224278 8695800 17235283 15929943 25416956 19380743 9716598 32296183 10204582 11314042 8995445
SHC1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 198.0 1.0 Omnipath 8808684 9083103 8551221 9126968 8621483 25416956 9252386 8524223 7535773 8662998 11302736 11827484 8995379 9541596 9175774 10207047 7717978 17673906 7744881 11505033 10523831 24189400 9927207 7650032 8810340 9045692 23178716 19531499 15812354 9129019 10356320 12485888 9461587 8114695 7514169 9566877 8939605 16371368 15341520 7529871 10891441 10749687 7524086 26645482 8491186 10592173 10049786 9171350 11707404 7537740 15688026 8663178 19380743 11782427 9544989 16436051 9434624 16713569 21725358 11964172 17314098 11792427 8195171 1465135 12213123 8647288 12955078 10477741 11707405 12577067 9199344 10080542 8112292 7760801 10570290 11997181 7798267 16520382 10961885 8950973 21706016 9448048 8662733 11370743 8051109 9733714 8621475 9254595 8294403 10748054 8621719 8940013 12441060 22057045 7505797 24737791 20697350 9886492 18174162 18273058 8235613 7963520 7523859
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
GRB2 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 145.0 1.0 Omnipath 9544989 9872323 7642581 15746962 11726515 8621483 23334917 16520382 11997436 21706016 10359574 8950973 7664271 16713569 16893902 16906159 21988832 19323566 9009162 10716926 11964172 7629168 9815779 10592173 9716598 8647802 28166272 7773778 7773779 18778683 8188688 10319320 8810325 9344843 23452850 11960376 8816480 10025673 7510700 8940013 12955078 9697839 12345678 10477741 8493579 8943292 12577067 7862167 9199344 8112292 7898932 10207103 8695800 19531499 10570290 7760801 20005866 19380743 9447984 8235613 8479540 7527391 14679214 8479541 17474147 7514169 7629138
IGF1R IRS1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10086337 10826997 11274345 12175651 12444011 12556535 12655147 12767520 16931767 17145802 17673906 19030972 21540285 24103846 24782617
IGF1R SHC1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10086337 10826997 12175651 12444011 12767520 16931767 17145802 19030972 21540285 24103846 24782617
SRC IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17389395 15212693 18691976 7559478 7493944 7537849 20068231 23472139 8550552 17016520 8940173 9480911
IGF1R IRS4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 9553137 18988627 11316748
IGF1R IRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 8662806 9852124 10471495
IGF1R IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 7541045 12444011 19030972 10082579 16931767 21798082 12220227 11259577 12767520 10826997 23331499 17827393 7504175 21071413 7559507 11572799 27856640 12175651 17570479 15829723 18988627 15629149 11557037 20670944 8530377 21540285 8776723 25886138 8662806
IGF1R SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12767520 15629149 7541045 17145710 8776723 7559507 14764897 17570479 16113100 24051437 17673906
INSR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 93.0 1.0 Omnipath 9083103 17145710 19901323 10803466 20230923 16497976 9121430 15592455 9446569 17389395 18578522 7559507 7537849 10482988 10764799 10921922 18452278 20068231 10592173 7499194 18669648 15629149 12522270 9685404 10896916 9927207 9593725 12237775 8702728 8610109 19651622 15212693 9741627 9710204 19664994 7685165 8626723 17016520 10816433 11075717
INSR IRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 19901323 7629118 9195949 18083107 23331499 19534553 7537849 17570479 18988627 7675087 11584304 7526222 12101187 8626379 8662806 8626723
INSR IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 10655627 7651388 25472611 1385403 18083107 12220227 23331499 28328746 7504175 19534553 7499194 7537849 7935368 11572799 11781100 10592173 17570479 17575262 18988627 12446583 15629149 10455177 15870194 11416002 12101187 17167487 8530377 8626379 8662806 11606564 2159922 8626723 16020478 16582879
IRS1 SOS1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8316835 8810325 9832424 8621421 8530377 9852124 9003010
IRS1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 9202037 10807918 7499194
IRS1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9492017 7782332 11208867 21071413 12960006 15316008
JAK2 IRS2 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
SRC JAK2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
SOCS1 JAK2 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 10485906 12193701 12223527 12811837 21469115 23124025
KIT JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8611693 7527392 15526160 9355737
SOCS1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 10421843 23331499 21071413 10455112 14522994 10064597 28258213 19287004 18508766 11314018 18988627 11971965 11713228 10975987 9202126 9344848
JAK2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9126968 7535773
SRC KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12878163 7520444 10523831
LCK KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17570479 9788619 24728074
KIT SOCS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10022833
LAT RAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17540168 11278486 11804587 12670394
LAT SHC1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10072481 10781611 10811803 11169415 12640133 14764585 16102570 16329184 19494291 19909365 23620508 25137453 7523143 7890616 8649391 8976179 9489702 9535722
LAT LCP2 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
LCK LAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16938345 12359715 12186560 27700984
LCK SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 19901323 20230923 16497976 9121430 15592455 9446569 17389395 18578522 10921922 10482988 10764799 18452278 20068231 18669648 12522270 9685404 10896916 9927207 12237775 8702728 8610109 19651622 9741627 9710204 19664994 17016520 10816433 11075717
LCK LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 16354835 21725281 8702662 10648627 10556826
RAC1 LCP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17540168 11278486 11804587 12670394
LTK SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 9223670
SRC MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 24728074 24034250 9837958 17570479
MET SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 9083103 11687594 9660480 14990987 24728074 8084588 8939605 8947042 7731718 11884620 15688026 14685170
RAC1 NISCH â—¼   UP_REGULATES ✅ + 11.0 1.0 ACSN 11121431 11274345 11544274 11756498 15157156 15229651 18000759 19151919 24459205 27331412 9655398
NTRK1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 8155326 9715270 8226808 15056278 10708759 8552402 9856458 23331499 10629055 10092678 12446789 8524391 25921289 7541035 8183561
SHC1 RAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17540168 11278486 11804587 12670394
SRC RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22163037 17991704 21798346 26816343 29036929
SRC RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11713247 17570479 16189514 10070972
RET SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 9393871 23331499 9047384 15677445 16189514 9047383 8183561
SRC SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 19901323 9388490 8939605 9096689 10971656 16497976 15592455 9121430 10891441 17389395 11687594 10329689 10482988 20068231 17570479 16189514 9685404 23109003 7516469 9927207 18840094 15688026 15212693 1409579 14963047 9710204 26551075 17016520 11075717
SHC1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 9544989 8631299 8621483 8950973 10891441 10783152 9278309 17673906 9344843 8294403 8021500 10025673 7520523 12955078 12577067 9199344 19531499 7760801 10570290 19380743 8235613 10675333 8114695
SRC SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17474147 9856337