MDM2
|
MDM4
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17159902
5219425
|
PPIB
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17361185
26344197
|
GAB2
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31980649
19172738
|
1433S
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SMTL2
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
1433B
|
FA53B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SMTL2
|
1433G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
1433G
|
FA53B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SMTL2
|
1433Z
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
1433Z
|
FA53B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
1433S
|
FA53B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
15778465
33961781
|
1433F
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
TAU
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28575131
26402096
|
SMTL2
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
1433S
|
GRIN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16189514
15778465
|
TAU
|
1433F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26269332
26402096
|
SMTL2
|
1433F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
1433F
|
FA53B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SMTL2
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
1433T
|
FA53B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ABL1
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
15696159
16888623
|
MDM4
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16511560
16511572
|
MDM4
|
1433F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16511560
29523541
|
LRRK2
|
P53
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
24725412
26384650
|
GAB2
|
1433F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
31980649
19172738
|
GAB2
|
1433G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
19172738
|
GAB2
|
1433Z
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
31980649
19172738
|
GAB2
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
31980649
19172738
|
HDAC5
|
1433G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
23752268
33961781
18951085
21081666
|
HDAC5
|
1433F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21081666
23752268
33961781
28514442
|
HDAC7
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
23752268
33961781
24255178
17369396
|
1433S
|
TRI62
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
MPIP2
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
15173315
16672277
|
1433S
|
PLD6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
1433T
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
20618440
33961781
26186194
|
K0930
|
1433F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
1433F
|
SH3B4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
33761321
|
ABL1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
ABL1
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
22649097
15696159
16888623
25852190
|
ABL1
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
15696159
33961781
16888623
25852190
|
ABL1
|
1433F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
15696159
33961781
16888623
25852190
|
MDM2
|
PPIB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
24583282
29876924
|
MDM4
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
29523541
16227609
18356162
16511560
21925390
|
MDM4
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16511560
17110929
29523541
18356162
|
MDM4
|
1433Z
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16511560
28514442
18356162
|
RON
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12919677
14505491
|
TNK1
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
25852190
|
TNK1
|
1433G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
25852190
|
TNK1
|
1433Z
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
25852190
|
1433Z
|
SH3B4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
15161933
33761321
|
1433T
|
RON
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12919677
14505491
|
RON
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12919677
14505491
|
1433F
|
RON
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12919677
14505491
|
TNK1
|
1433F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
25852190
|
TNK1
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
25852190
|
1433B
|
ARAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
31980649
29777862
24255178
25852190
32707033
|
ARAF
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
32707033
29777862
31980649
25852190
|
1433F
|
LRRK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
31046837
23075850
20642453
29541021
|
1433Z
|
NED4L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
34294877
15161933
20936779
|
M3K2
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
32707033
33961781
26496610
|
RFWD2
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20843328
21625211
|
1433S
|
KIF23
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15778465
31586073
|
M3K2
|
1433Z
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
28514442
9452471
26496610
33961781
32707033
|
1433Z
|
IF4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17361185
26344197
|
1433S
|
UBP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
29880877
15778465
|
1433S
|
NED4L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34294877
15778465
|
1433S
|
IF4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17361185
26344197
|
1433S
|
TRI32
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
23444366
15778465
|
1433S
|
SH3B4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15778465
33761321
|
1433S
|
GAN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15778465
26186194
|
P53
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10713716
16713569
10629029
|
ARAF
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31980649
34017080
20130576
|
EGFR
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
HDAC7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
TAU
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
1433F
|
KIF23
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
14676191
17979178
26496610
33961781
31586073
|
1433F
|
HDAC7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
23752268
17979178
26496610
33961781
20224040
|
1433B
|
SH3B4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
17353931
33961781
33761321
|
MPIP2
|
1433G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
26496610
33961781
27432908
16672277
|
RON
|
1433Z
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12919677
14505491
|
1433Z
|
K0930
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
17353931
33961781
26186194
|
1433F
|
UBP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
17979178
33961781
|
1433S
|
K0930
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
15778465
26186194
33961781
|
1433T
|
K0930
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
17353931
33961781
26186194
|
ARAF
|
BRAF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
BAD
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
ABL1
|
1433Z
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15696159
16888623
25852190
|
BAD
|
1433G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
31980649
10880354
33961781
20936779
|
BAD
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21900206
28514442
16189514
31980649
11697890
33961781
24255178
9369453
|
BRAF
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
23153539
28514442
31980649
18332145
20141835
23934108
31015455
11325826
23680146
20130576
26466569
22169110
33961781
34017080
28806393
20212043
25155755
22605333
|
1433B
|
LRRK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
31046837
20642453
24947832
24510904
|
HDAC5
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15923258
23752268
15367659
|
1433S
|
MARK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
15778465
|
1433F
|
MARK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
16959763
14676191
17979178
29089450
33961781
32707033
20642453
|
BRAF
|
1433F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
27034005
31980649
17979178
33961781
32707033
|
TRI32
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
23444366
24255178
|
1433S
|
TNK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15778465
25852190
|
1433S
|
M3K2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15778465
26496610
|
1433F
|
M3K2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
32707033
17979178
33961781
|
ABL1
|
1433G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
15696159
25852190
33961781
16888623
30021884
|
1433F
|
ARAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
11969417
29777862
17979178
26496610
33961781
25852190
32707033
|
1433S
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
31980649
11697890
21988832
20005908
33961781
20179209
|
BAD
|
1433F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
31980649
11697890
21988832
17979178
33961781
9369453
|
1433S
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
19166854
17546054
|
RAF1
|
1433F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
11969417
31980649
11697890
10620507
17979178
26496610
8702721
16041367
33961781
16093354
25852190
32707033
|
LRRK2
|
TAU
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22303461
24113872
26268594
|
GAB2
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
19172738
|
1433T
|
KIF23
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
15161933
17353931
33961781
31586073
|
1433Z
|
KIF23
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
15161933
20451386
14676191
33961781
31586073
|
1433F
|
HDAC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
23752268
31040226
18045992
17979178
26496610
33961781
27684187
|
HDAC5
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
23752268
15367659
23393134
20716686
33961781
21081666
22649097
|
1433T
|
MARK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
15161933
17353931
29089450
33961781
32707033
20642453
|
1433S
|
BRAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
27034005
31980649
28628118
15778465
28205554
27684187
|
1433S
|
HDAC7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
23752268
18339811
15778465
|
1433Z
|
HDAC7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
23752268
15161933
33961781
20224040
|
HDAC7
|
1433G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
23752268
17353931
33961781
15324660
|
HDAC7
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
23752268
15161933
16980613
33961781
16956611
17369396
|
1433B
|
K0930
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
17353931
33961781
26186194
24255178
15324660
|
1433B
|
M3K2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
17353931
26496610
33961781
24255178
32707033
15324660
|
M3K2
|
1433G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
26496610
33961781
32707033
15324660
|
1433G
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
15778465
33961781
26186194
15324660
|
1433G
|
P53
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22653443
18812399
15324660
19933256
|
1433G
|
1433F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
17979178
26496610
22863883
33961781
15324660
26344197
|
1433G
|
K0930
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
17353931
33961781
26186194
15324660
|
1433G
|
UBP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
17353931
33961781
15324660
|
1433G
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
17085597
20618440
22863883
33961781
15324660
|
1433F
|
1433Z
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
17979178
26496610
20618440
22863883
33961781
26344197
|
1433Z
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
26496610
20618440
22863883
33961781
|
NED4L
|
1433F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
34294877
33961781
16716084
15677482
|
1433S
|
TRI25
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
12075357
|
1433F
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
17979178
26496610
20618440
22863883
33961781
|
TAU
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15650334
31413325
26269332
|
1433T
|
SH3B4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
17353931
33961781
33761321
|
ABL1
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
24658140
16273093
25402006
7678409
|
ABL1
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16702947
25624478
12110584
|
BRAF
|
ARAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
25241761
31980649
28628118
17979178
20130576
34017080
33961781
28205554
|
1433G
|
ARAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
31980649
28628118
29777862
17353931
28205554
25852190
32707033
15324660
|
1433Z
|
ARAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19933840
31980649
20052757
28628118
29777862
28205554
20936779
25852190
25266655
32707033
|
1433S
|
ARAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
28628118
25852190
15778465
28205554
|
BAD
|
1433Z
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11526496
25770209
28514442
17389761
11410287
11697890
21988832
31980649
33961781
19667065
20936779
25266655
19427857
21076048
23397142
|
1433Z
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
15225635
23956138
15389569
19531499
24658140
25402006
15657067
|
EGFR
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
33391517
24189400
24658140
25402006
16799092
29880877
15657067
|
EGFR
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20029029
31980649
24189400
24658140
25402006
15657067
|
MDM4
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
10629057
32300648
25512388
21988832
25384516
25809483
17616658
25105592
12874296
31796886
29295817
32075226
20705607
17301054
22493164
25703327
27777309
29523541
27617579
23028042
20473904
22120712
22333590
22902369
22745160
12860999
19432880
21925390
28205554
25659040
19838211
33985974
16055726
25961923
32427989
18566590
22266850
18219319
29057323
10608892
30598450
29524278
25825738
17159902
24813712
31024344
27621617
15604276
29262653
19619542
10218570
28628118
16227609
10827196
12393902
24755078
20724842
34551723
27215386
11606419
20484049
12370303
23671280
26001071
26720344
33961781
12483531
23946421
19683495
26359458
|
MDM4
|
P53
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
10629057
29023092
30672125
31152661
17110929
19521340
10075736
30832340
22807444
12874296
25609649
11528400
24445145
17080083
18677113
20705607
27249653
9226370
17301054
18485870
26148237
27114532
16024788
22374672
24127580
18316739
26876197
29523541
21088494
23028042
24667498
30045945
20515689
25464845
22745160
19432880
21925390
28205554
20174603
21965653
25961923
21075307
22266850
8895579
28487147
32511789
10608892
30598450
25825738
19305137
19255450
11223036
15604276
16713569
28628118
16227609
10827196
12393902
20724842
24659749
12370303
23671280
17875722
33961781
31462704
26186194
23946421
31066983
19075013
15916963
19153082
|
MDM4
|
1433G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29523541
24190973
16511560
21148311
22556425
16511572
|
1433B
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
16189514
31980649
10620507
7935795
7882972
25852190
19595761
7644510
11697890
12360521
32707033
8085158
8702721
10848612
16041367
33961781
16093354
12620389
24255178
|
1433S
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
11697890
16041367
15778465
16093354
25852190
26578655
|
1433T
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
31980649
7760835
11697890
17353931
10620507
15618521
16041367
7479742
33961781
8663231
16093354
25852190
32707033
10757792
|
1433G
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
16189514
31980649
11697890
28628118
17353931
10620507
28205554
8702721
16041367
33961781
16093354
25852190
32707033
10433554
|
1433Z
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
20052757
10620507
7935795
25852190
9261098
12861023
8601312
14688280
16306228
28205554
22222486
20679480
7628630
19049963
11697890
10611249
9632690
17979178
9153224
15664191
7939632
32707033
8085158
28628118
10887173
16041367
16093354
|
1433T
|
LRRK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24947832
22612223
29519959
31046837
20642453
24510904
24351927
23075850
|
1433S
|
LRRK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31046837
24510904
28202711
|
1433G
|
LRRK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23075850
20642453
24947832
28202711
|
1433Z
|
LRRK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24947832
26375402
31046837
20642453
24510904
24351927
23075850
|
RFWD2
|
P53
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15103385
16713569
23736031
29379285
16931761
21625211
27534417
|
1433B
|
KIF23
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
17353931
26496610
33961781
31586073
15324660
|
1433G
|
KIF23
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
20451386
25658096
17353931
26496610
33961781
31586073
15324660
|
1433G
|
HDAC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
23752268
25416956
31040226
17159145
18045992
17353931
11504882
33961781
27684187
15324660
|
1433S
|
HDAC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31040226
23752268
16767219
15778465
27684187
|
HDAC4
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
11470791
23752268
15161933
31040226
23393134
27684187
18045992
15964851
23444366
17470459
22466704
33961781
22649097
|
1433B
|
MARK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
16959763
17353931
29089450
33961781
24255178
32707033
20642453
15324660
|
1433G
|
MARK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
16959763
17353931
29089450
33961781
32707033
20642453
15324660
|
1433B
|
BRAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
27034005
10931830
32707033
31980649
17353931
33961781
24255178
12620389
27684187
15324660
|
1433T
|
BRAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
27034005
32707033
31980649
18332145
17353931
17979178
31015455
33961781
27684187
15324660
|
1433G
|
BRAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
27034005
32707033
31980649
28628118
17353931
17979178
33961781
28205554
27684187
15324660
|
1433Z
|
BRAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
27034005
32707033
15161933
31980649
28628118
17353931
17979178
26496610
33961781
28205554
27684187
15324660
|
1433B
|
UBP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
17353931
26214742
33961781
24255178
15324660
|
1433B
|
MPIP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
21558810
12871587
26496610
30468767
33961781
15173315
17292828
27432908
10713667
16672277
7644510
|
SH3B4
|
1433G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
33761321
17353931
33961781
20936779
15324660
|
1433Z
|
1433G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
28628118
31536960
26496610
20618440
22863883
33961781
28205554
26344197
|
1433G
|
NED4L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
34294877
33961781
20936779
|
1433Z
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
15161933
17361185
20618440
22863883
33961781
26186194
|
1433Z
|
P53
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22653443
9620776
16376338
16713569
|
1433Z
|
UBP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
29473952
15161933
17353931
33961781
15324660
|
1433Z
|
MPIP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
15629715
26496610
12764136
33961781
12766774
17292828
27432908
10713667
16672277
|
P53
|
1433S
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11896572
14517281
21625211
20206173
17546054
|
UBP8
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
15161933
23333852
17353931
33961781
15324660
|
1433T
|
MPIP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
16713569
26496610
15629715
33961781
10713667
|
MPIP2
|
1433F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
26496610
33961781
27432908
10713667
16672277
|
MDM4
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
15604276
5217417
|
MDM4
|
MDM2
|
â—¼ COLOCALIZATION
|
✅
|
|
0.93
|
0.93
|
mint
|
17159902
5219425
|
BRAF
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
HDAC5
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
23752268
10869435
33961781
24255178
21081666
|
1433Z
|
HDAC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
28514442
23752268
15161933
33961781
21081666
|
RAF1
|
BRAF
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
8396417
22510884
|
HDAC4
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
23752268
31040226
10869435
33961781
24255178
27684187
10958686
|
1433Z
|
MARK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
15161933
16959763
14676191
29089450
16968750
26496610
16306228
33961781
25852190
32707033
20642453
|
1433F
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
17979178
26496610
33961781
24255178
26344197
|
1433G
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
17085597
33961781
24981860
24255178
15324660
26344197
|
1433T
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
17085597
20618440
22863883
33961781
24255178
|
1433Z
|
1433B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
31536960
26496610
20618440
33961781
24255178
26344197
|
P53
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
19303885
25417702
34408321
17268548
23252402
23880345
22807444
15094782
20962272
12529318
21726810
22124327
18981217
16173922
23318437
15558054
22524527
30584071
31626714
22301280
32516735
20174603
22912717
21075307
15848166
18566590
23483203
26882543
23402884
14671306
15001357
10889512
17908790
19411846
10640350
21561866
14499615
33503543
21986495
24998844
15908921
26673821
17098746
25362358
32066565
25739118
29295817
34362424
16595680
20591429
27336364
22745160
24462112
32427887
18467333
26578655
23261415
9271120
16055726
19357310
31591476
23169665
16338390
10608892
30464405
15542844
12612087
22266868
15550400
22331460
22914926
19071110
7686617
14559824
20959462
19941302
14596917
25512388
27129163
19597489
25609649
32904724
11351297
29121928
22487680
11709713
24127580
10562557
15358376
21584881
25312347
27826076
19098711
24980433
24413661
21887275
17116689
14612427
30948704
26001071
19857530
33061576
31138778
23802716
20234175
25313037
21988832
17616658
11744695
17666403
22525275
12897156
25156994
33020477
11925449
16152627
29876924
30244831
1614537
17363365
22474335
11112690
23443559
17297477
27905468
19085961
20479273
31940492
21261729
14517261
26908445
16866370
27893708
22653443
17470788
10488081
23370271
19223463
16751805
26556313
10734067
19411066
11223036
27856536
14704432
20124408
24240685
24842904
32901886
22948151
19234109
35140242
21084285
32894144
17848574
22737255
10561590
25168242
10435614
11697899
25543083
21572037
22920093
18604177
32874188
22659184
17591690
16845383
22444248
31239268
25283148
26186194
24200963
23826318
7689721
20047188
24314634
12167711
15308643
17318220
21857681
11431470
18815136
15950904
20705607
17525743
26876197
31177307
9529249
22374672
12915590
33650658
10601022
20837658
18223694
30097011
28205554
32334023
15247280
23776465
21268072
27308622
11713288
18234963
9582019
18784078
29487367
23776060
11713287
20484049
26720344
9131587
30109812
33961781
24361594
32807901
31066983
15824742
11562347
21454483
22157679
21088494
11070080
22575647
22083959
26540344
15210108
18332869
32528731
18172499
11094089
21132010
16414131
10827196
27031960
10892746
15280377
16023600
18665269
10202144
15058298
29549180
16212962
16905769
11278372
20657550
9809062
15295102
26238070
22391559
18061646
17310983
18485870
9278461
21925390
20659896
9824166
23150668
25637791
30598450
19160491
28605833
12690203
22467867
31594538
11572869
11384992
11486026
27807478
17936559
30679555
16678796
30252118
31652301
15144954
22411991
22084066
30175854
21478269
27543608
16624812
17290220
32097779
17301054
20694676
11714701
24667498
20395212
16547496
12381304
8058315
22266850
29755129
22085928
17159902
10196247
21316347
27886165
27215386
25384516
7926727
16964247
19081178
32198344
11046142
28549433
26350565
31533005
12867035
10321734
19590512
22991965
25277184
24207125
18541670
19166840
25103245
30320919
26883110
20235143
17139261
11597128
21071676
19568783
18813780
19805293
17056014
17989425
21317885
17234751
20588255
21170087
10347217
11839577
25954860
21060154
24926618
21750659
16331255
29269425
27811966
19305137
24659749
9450543
23201157
30879903
16870621
28362432
21149449
20570896
23609977
33765973
27106262
33355139
34040386
22588298
22389628
19033382
18264029
27462439
31092600
12208736
17369817
28082682
16579792
23246961
20708156
15013777
21465263
28542145
23572512
19483087
31665549
22975381
17438265
15604276
11178989
24488098
16432196
22227409
28628118
30005830
20639885
20847049
9363941
31406141
19816404
26475964
29899406
16861890
30320499
20660730
19332559
14702041
11284721
18316739
19837670
25464845
12426395
10681559
17302414
16107876
22510990
15154850
21098709
19106616
10722742
19188367
22366412
29524278
21084564
23134341
25624478
30455251
20173098
12620407
9223638
16713569
17426254
31647545
10766163
30454706
21471462
24621507
23652204
19153082
8875929
31152661
18309296
31968249
31796886
15122315
30532073
10980696
17080083
15064742
11285227
29547122
21965653
33495326
23728348
15242646
17347673
12842086
12944468
19255450
23671280
22916255
17875722
30355102
14741215
23946421
20591651
15053879
28514442
25241761
24567357
16215989
19656744
30832340
22262183
27249653
26203195
16857591
15313915
15933712
28223335
20542919
12552135
24643130
27282385
20080206
28553961
22819825
33579943
16159876
9724739
17380154
22318540
29997244
29670376
22103682
22032989
28394340
31903119
|
HDAC4
|
1433Z
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
23752268
31040226
15161933
15964851
11504882
33961781
11486037
27684187
|
1433Z
|
TAU
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28575131
27548710
17317006
10840038
23962087
29659825
19647741
15650334
26269332
19138662
12551948
|
1433B
|
TAU
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
10840038
29382714
26269332
26402096
12176984
|
BAD
|
1433T
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
15280438
15694340
31980649
16713569
11697890
21988832
10611223
8929531
33961781
9369453
|
MDM2
|
MDM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ABL1
|
MDM4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
20651945
29262653
26148237
19075013
20841568
28690977
29348869
|
ABL1
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
32.0
|
1.0
|
Omnipath
|
23331499
12110584
20651945
29065514
22352870
16702947
25973395
27626309
21081495
27956626
20841568
14757045
19738896
15212693
28690977
|
ABL1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
24430869
15192046
33889303
16273093
16943190
14760089
29880877
15618223
33574089
8910327
12631709
25173817
25402006
20841568
33947961
34107301
34469737
19915609
32019812
2022651
34290403
33707748
15329413
7678409
9733788
8490966
28338646
3263271
15901825
2022652
10069801
7506413
24658140
8408058
34385595
31980649
1314835
7741752
18668345
28724430
12648464
25073158
26079946
34155348
|
RAF1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
11532940
12107820
12566895
14764585
15516985
19289794
19565474
24027568
8929532
9069260
|
RAF1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
38.0
|
1.0
|
Omnipath
|
11983683
12444011
10880354
19030972
19667065
22096607
15849194
16931767
17535812
16103085
9381178
23162742
12107820
18402774
12767520
10826997
8929532
8929531
12175651
25241761
19565474
10949026
19165420
9069260
21540285
17242355
23397142
19289794
|
MDM2
|
MDM4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
69.0
|
1.0
|
Omnipath
|
17145710
10218570
17616658
16511560
22266850
12874296
21925390
25825738
21988832
25512388
16227609
22493164
22902369
25659040
18219319
12963717
15604276
18566590
12370303
19838211
26359458
27617579
25809483
34551723
10608892
23028042
22120712
25703327
12860999
32300648
16055726
24813712
17301054
12483531
23671280
17159902
27621617
25105592
20484049
20724842
27215386
10827196
26001071
11606419
23946421
19683495
20705607
24755078
25384516
20473904
12393902
|
RAF1
|
MARK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
25435214
20179705
20141835
16364920
20130576
15035987
25907612
|
BRAF
|
MARK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
25435214
20179705
20141835
16364920
20130576
15035987
25907612
|