TP53
|
ATF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11350971
10984493
|
ATF2
|
CYP19A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21393445
12520731
|
ATF2
|
CYP11B1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11196473
11014212
|
ATF2
|
DDIT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20102225
23661758
|
ATP2A2
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PPIB
|
DTX3L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
TP53
|
MSH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12209975
|
PPIB
|
PNPLA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
SHPRH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
TP53
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17184779
5219502
|
TP53
|
SULT1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
TP53
|
ABCG2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23838170
20600004
|
TP53
|
PRL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16227626
9806359
|
TP53
|
TBXAS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
14586398
|
TP53
|
GPX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16980608
|
TP53
|
ALOX5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17018618
|
LTC4S
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
18758483
|
TP53
|
IRF5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
GPX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
ABCB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10783169
|
VCP
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSPA5
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
KCNQ1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TRAF6
|
TRAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
ASPSCR1
|
VCP
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
VCP
|
ASPSCR1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
PPIB
|
KRT28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PRKACA
|
PLN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22707725
21108950
|
P4HB
|
PPIB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
NOC2L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
COTL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
SERPINH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
OBP2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
TRAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PPIB
|
ASPSCR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
CCDC38
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
PDIA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
FAM86JP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
KICS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
FLNC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
IRF5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
CPSF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
RAB11FIP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPIB
|
CCDC190
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PRKAR1A
|
PRKACA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
24855271
1252328
|
CACNA1C
|
BSG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
HDAC6
|
HSP90B1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19158084
|
HYOU1
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
HSPA5
|
SLC22A8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
P3H1
|
CRTAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
P4HB
|
PDIA2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
23167757
8401719
|
ADRA1A
|
SCN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
PCM1
|
DDIT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27107012
33961781
|
LRRK2
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
24725412
|
CFTR
|
PPIB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31324722
17110338
|
BMI1
|
PPIB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24457600
34316702
|
BMI1
|
NCBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24457600
34316702
|
MATN3
|
PDIA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16287128
23956175
|
DDIT3
|
ATF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
23661758
20102225
|
HDAC6
|
CFTR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31501480
22069321
14675537
|
PEX19
|
RDH12
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
NQO1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
MDM2
|
PPIB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
24583282
29876924
|
ATP2A2
|
PLN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
CFTR
|
PDIA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26618866
31324722
29924966
|
BANP
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
TRAF6
|
TRAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
25416956
21988832
33961781
21516116
27107012
|
PPIB
|
APOB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12397072
16713569
|
AKR1C3
|
AKR1C4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
SULT1A1
|
SULT1A3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
PTGS2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
ALOX5
|
COTL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
MAPK1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
TRAF6
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
TPM1
|
TPM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
PDIA4
|
APOB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12397072
9694898
|
HSP90B1
|
OS9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
OS9
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
PRL
|
PPIB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16713569
10935542
|
DNAJB11
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
CFTR
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
KCND2
|
KCNIP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
SGTA
|
UBQLN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
MAPK1
|
ALOX5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12670876
12205041
|
MAPK1
|
ATP1A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15069082
14976217
|
TP53
|
MSH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11350971
8630028
|
TP53
|
ABCC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11483599
10792001
9865734
|
TP53
|
NQO1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12149651
22154326
17077087
|
TP53
|
IRF5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11973653
20507321
|
TP53
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15212714
20097177
18840615
|
TP53
|
GSTP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18505928
|
PDIA4
|
PPIB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
34079125
24981860
22665516
30021884
|
PRKACA
|
LRRK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
21390248
24351927
|
OS9
|
VHL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
12351678
15652751
15721254
|
PRKACA
|
CACNA1H
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19131331
|
PRKACA
|
KCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10681507
12451113
20045463
|
PRKACA
|
KCNJ4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11749379
8893032
19635485
|
TPM2
|
TPM1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
7568216
33961781
26186194
3857586
30021884
22939629
|
P3H1
|
CRTAP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
33961781
26344197
30021884
|
KCNQ1
|
KCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19521339
24713462
11101505
11104781
19114714
|
TRAF6
|
MAP3K7
|
â—¼ UBIQUITINATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
18758450
|
TRAF1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
8153045
21516116
|
HDAC6
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
24882211
23703321
|
PTGDS
|
UBQLN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
SDF2L1
|
SGTA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
PPIB
|
SGTA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
PPIB
|
UBQLN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
TOP2B
|
TOP2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
8710863
22939629
|
SNTA1
|
SCN5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
9412493
18591664
|
HSPA5
|
HYOU1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
942.0
|
0.94
|
STRING
|
36370105
|
ABCC8
|
KCNJ11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
ATP1A1
|
FXYD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
VCP
|
ASPSCR1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
21900206
2001699
8089645
|
PRKACA
|
PRKAR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
ASPSCR1
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
ATP1A1
|
ATP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
KCNJ3
|
KCNJ5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
TP53
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.99
|
0.99
|
mint
|
17139261
5219401
|
MAP3K7
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
MDM2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
GRIN1
|
GRIN2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ATF2
|
PTGS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11901151
17591797
11278336
12057991
16007171
|
MAPK1
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10777545
17081983
21098032
9430721
12110590
20068231
19690332
15304344
19413330
10878576
15192015
7737129
18669648
19647037
|
PRKACA
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
1661585
15105425
92095966
|
PLN
|
ATP2A2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11854448
10809745
11526231
16189514
12838339
|
COL1A1
|
P4HB
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
4.0
|
1.0
|
Reactome
|
2543975
16591531
1323838
14500733
|
DDIT3
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23667408
22905241
10218478
22802018
10472808
20801537
|
MAPK1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
14965474
9765199
15116093
21675959
23443559
10781582
25241761
10446957
10958792
11409876
11709713
21147777
10673501
11551930
15867353
11875057
12091386
|
MAPK1
|
KCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11080179
12077183
|
TP53
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
201.0
|
1.0
|
Omnipath
|
23150757
20948295
10871862
10914734
21422812
21957016
14532965
22290440
20663877
20547751
11591713
24339722
11840331
22223137
16492744
15843377
22948151
7888679
20156675
21217645
22180176
8319905
9707425
15831521
17690113
9649502
10688649
9194564
15917661
15090541
20837136
8187772
10788589
17907153
15192123
8440237
11964305
16510138
10856296
15580300
7624148
12208736
21211512
16624812
17848574
11245471
21637567
20588255
10562557
9525742
9270029
16479015
19941079
14602726
15024021
18814047
20036872
10718212
18852133
12374749
18397889
25016801
12755686
22081073
22245141
23365201
8957072
22197810
15856024
20703075
23483203
9645455
19648117
20331637
22301280
14743206
23982177
9486848
15734740
19638633
19671680
17310983
10469568
20659896
10072445
21097889
17237821
11748232
11085543
21750655
16337599
21295542
1614537
9815889
9070662
16585169
9472631
17936559
17139261
11328884
12887889
20858413
9858609
14610316
20080970
19505873
11313463
15684615
18359851
18783169
16202543
9267820
12235242
14990790
15851483
7587074
18336191
21478269
17043642
15361831
18025460
23612020
10208414
11756653
24389645
9071998
9430645
9400998
9371494
23149414
22532570
9271120
10777217
22383580
18781178
12606552
14514686
17318220
11127813
16571800
19085961
9207798
10891494
10065155
11593391
14570892
12902982
19649205
20124454
17390010
19955655
12138177
19663772
23581014
15908423
10321740
23150759
19837670
10348346
18632610
9294611
11956627
12750288
12851404
8313378
9135153
15735665
7958853
8247544
9535786
16501602
18566224
8910340
11046142
9405685
7936649
12173040
17329361
21451571
14704432
23874713
18333294
19541936
22787160
18585004
22085928
12080472
7651818
11179471
10949923
19428175
15592502
8413278
11714701
10566557
18583933
9681831
15550242
15007388
19590512
|
MDM2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
559.0
|
1.0
|
Omnipath
|
20657550
30005830
17616658
9529249
10321734
33650658
9724739
24462112
24621507
15933712
23826318
24667498
22948151
22653443
23776060
25313037
25241761
19303885
16857591
23246961
19033382
20591651
21149449
25417702
15122315
16579792
27543608
29670376
12208736
17848574
26673821
25277184
23443559
23318437
21060154
15210108
19805293
8875929
8058315
21471462
17879958
25362358
23169665
22301280
21584881
20124408
10980696
26876197
17310983
17380154
15058298
24567357
18665269
30109812
25637791
18467333
22337874
22227409
22389628
15242646
22510990
15950904
15001357
19483087
26540344
14559824
21986495
26556313
20708156
19901969
33765973
32528731
11562347
10202144
22374672
10722742
22083959
21965653
17098746
19234109
30679555
16107876
12690203
22525275
19071110
28542145
12620407
20837658
27129163
9131587
24240685
27031960
10681559
19305137
11744695
19188367
16023600
24659749
17347673
12944468
20395212
22084066
20639885
21454483
12897156
16432196
10347217
10706102
11178989
20174603
16751805
15542844
12842086
11431470
11384992
25739118
15064742
23402884
27462439
16905769
22124327
27215386
12867035
22588298
27336364
14702041
16152627
23776465
22262183
21132010
19411846
18309296
23483203
11709713
18981217
14612427
22920093
23671280
24980433
27905468
25168242
21750659
26238070
22737255
23609977
27282385
20847049
20705607
21075307
28082682
17297477
11697899
17936559
24361594
19098711
15469934
34591612
24998844
16212962
11094089
12915590
17116689
11713288
15144954
23201157
10608892
17591690
25156994
17301054
22444248
26883110
26001071
19160491
22157679
24413661
19357310
23802716
15280377
21317885
11597128
19579266
25624478
18061646
21088494
9223638
10435614
31177307
11331603
22391559
20570896
19941302
9278461
18485870
15604276
18566590
12612087
11046142
14704432
26186194
10935507
16173922
14596917
17159902
25543083
19656744
15848166
18316739
22266868
17056014
19255450
21561866
19590512
11839577
22991965
22266850
24200963
11285227
11713287
22975381
19081178
20660730
26475964
16678796
23261415
20173098
17666403
25464845
32427887
23252402
17438265
20959462
22659184
17470788
22912717
17080083
15247280
19332559
17989425
16870621
18813780
20235143
11278372
10562557
25609649
10561590
19411066
17908790
19568783
7926727
21925390
21988832
24127580
18604177
14499615
17371838
17525743
33061576
21887275
26578655
21084564
16861890
20694676
12552135
22914926
17363365
24643130
1614537
22916255
12381304
34992144
12167711
19857530
15053879
10889512
11486026
22103682
16713569
17110336
17426254
10640350
21316347
21478269
15154850
12529318
16595680
16414131
19597489
23880345
27893708
7686617
27811966
17318220
29997244
27308622
19166840
35044719
16159876
24314634
15313915
25283148
22032989
24926618
18172499
19837670
16215989
23134341
26908445
9824166
18451149
21170087
23572512
21465263
22807444
15013777
16845383
10488081
23946421
11714701
25384516
22474335
25312347
23370271
23150757
18541670
22318540
11925449
21572037
24488098
32066565
17268548
20542919
11572869
16338390
21857681
23150668
19223463
20234175
20484049
11070080
20591429
22575647
11351297
16624812
22411991
20588255
17369817
11223036
15908921
9582019
25103245
17302414
21071676
9450543
31968249
34562520
18332869
14671306
21084285
27856536
30464405
26882543
21726810
33020477
21261729
21268072
12426395
16964247
20659896
19106616
22331460
23728348
10827196
22524527
21098709
9363941
17139261
20080206
14517261
22487680
31652301
17290220
27106262
16866370
24207125
28223335
9271120
15550400
7689721
26350565
10196247
27807478
10766163
15558054
35371302
26203195
29487367
25512388
25954860
18223694
15824742
24842904
14741215
16055726
22085928
32894144
18234963
17875722
18815136
15295102
15308643
15358376
22819825
15094782
|
TP53
|
ABCB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
1346476
18234965
8554604
8898977
10745175
19714248
9988237
10029407
11096091
11172607
11920581
17952118
8679460
9112432
11350951
8502478
11483599
7949467
|
TP53
|
PTGS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21187340
16713569
11687965
21763744
|
TRAF6
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11274345
12150927
12620219
14660645
15125833
16252010
17948050
18264787
18758450
18922473
19161412
|
TRAF6
|
IRF5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
32494619
15665823
19786094
18824541
|
TRAF6
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
17145710
19675569
17947236
19843958
10882101
19521662
11259596
17079228
28024152
31885808
19112497
22924441
10094049
27501752
18922473
11518704
11809792
16517750
19232515
10702308
16410796
14633987
19820695
22851693
10921914
18758450
12496252
12609980
21822258
12242293
25963657
24434549
27249171
22643835
21245467
17965022
26038599
|
VCP
|
OS9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
19002207
21357747
18502753
18711132
18264092
23867461
|
PRKACA
|
PLN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
2544595
12134142
3759968
10988285
12692124
9468536
33897445
|
PRKACA
|
CFTR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
28003367
23060444
25867080
21455600
30600261
1716180
28242698
19328185
32102849
92316961
19095655
14602047
7530719
10581361
11053017
9385646
25330774
15657296
1377674
|
PRKAR1A
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
17145710
15655353
17353931
26687711
11834733
24855271
32296183
24700472
9405392
25477193
|
PRKACA
|
KCNH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10837251
19651622
18791070
10488078
11953308
|
PRKACA
|
CACNA1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
8664319
8612821
28119464
7621818
9247274
29123182
2174428
10984483
10514522
|
PRKACA
|
RYR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10830164
29760186
14532276
14715536
|
PRKACA
|
KCNJ3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19151997
|
PRKACA
|
ALOX5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16230355
26210919
15280375
|
NCBP2
|
METTL14
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9409616
24316715
24407421
24981863
|