Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SOX2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath
AHR CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12203118 24431146
CDKN1A TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 16616141 5218511
AR CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10076995
CEBPG SLCO1B3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15322262
CEBPG CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12695546 12542705
CEBPG PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9774647 8626491
SP3 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20435036 20407012
TP53 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
EGFR PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19531499
EGFR ABCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12196520
GART IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
WT1 MLH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23042785 18829110
TP53 MLH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15781865
NR1H4 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19028791 19864602
TNF CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21887257 19287455
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
TP53 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
PLAGL1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22001409 11360197
TP53 ABCG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23838170 20600004
IKBKB TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19196987 0812256106
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
TP53 ABCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10783169
TP53 TAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
SP1 GGH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31739835
KLF12 PPIB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPIB PDIA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GNAS ADCY4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9228084 21406690
GNAS ADCY3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9228084 21406690
SP3 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18065760 15554904
SCARB1 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RELA JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17310108 10646503
JUN UGT2B15 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19487245
JUN CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11278771 16729332
JUN CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14742674
JUN ABCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23747343 12526103
JUN PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17138645
CHUK IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 12799363 23430059
CHUK IKBKB â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 12799363 23430059
RELA CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114294
RELA IKBKB â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 12842894 5216511
SP1 SCARB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10801817 12816880
SP1 ABCB8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21046154
SP1 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9875228
SP1 ABCC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22086197 10373428
SP1 ATP1A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24219545 15462673
SP1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12683994 18064385
SP1 ABCC6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374464 17214963
SP1 SULT1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9516473 15383623
SP1 ABCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17272513
SP3 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12637574 12888570
NR0B2 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21613300 18775915
ESR1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19797124 20819530
NFKB1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114294
NFKB1 TAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18694960
HSPA5 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CEBPB HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23251594 22905241
CEBPB UGT1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9614204 20028978
CEBPB SLC10A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14701722 11031103
NR1I3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15268900 21389059
WT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
ESR1 ABCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15456840 23747343
ESR1 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16511840 23038705
ESR1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
ESR1 SCARB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21820658 23192982
ESR1 NME1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
ESR1 SLC2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14605097
AR ABCC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 16020662
AR HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 21125667
AR ABCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15520169 20610535
AR ABCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23368743 20610535
AR SLC2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17426252 20610535
AR AHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 23689136
RXRA AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15650026
AHR AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19815066 17392787
AR RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15650026
AR CYP3A5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17116727
HYOU1 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 SLC22A8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AHR NR1I3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17627975 18978342
NR1H4 ABCC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24498169 11706036
NR1H4 SLC10A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21330447 12483266
NR1H4 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14527955 24007921
NR1H4 ABCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17127344 21330447
NR1I2 CYP3A5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21733184 15252010
NR1I3 UGT2B7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19541828 21415305
ABCA1 RXRA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18782758 21507939
RXRA ABCC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12145812 21689630
RXRA ABCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17272513
RXRA ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14527955 24007921
ABCG8 ABCG5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16870176 5218866
NR0B2 SCT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16888194 19372104
NR0B2 ABCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12198243 22424975
NR0B2 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22982774 16455805
ATP1A3 ZNF20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP3 ATP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10811658 24219545
SP3 PTGS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18599619 18584335
ID4 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21531766 23613880
SOX2 ABCC6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21531766
UGT1A10 UGT1A7 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
SP3 SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15247906 11517158 10825178 16734381 9329821 12414801 12200149 23825960
NR1I2 RXRA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16189514 23160820 9489701 15604093 9727070 26855179 22976785
UGT1A7 UGT1A9 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
ESR1 PURA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
CFTR PPIB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31324722 17110338
ESR1 HYOU1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 25604459
GNAS SCTR â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CEBPG JUN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 23661758
JUN TOP2A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 8387155 25609649
NR1H4 ESR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17333335 25675114
ESR1 PDIA6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33731348 25604459 31527615
ABCD2 ABCD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24658140 10551832
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CEBPB SP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16651265 12847250 12665574
ESR1 RXRA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9717844 23403292 9121466
IKBKB NFKB1 â—¼   PHOSPHORYLATION ✅ - 0.84 0.84 Signor 11158290
CEBPB ESR1 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
CFTR PDIA4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 31324722 29924966
JUN SP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CHUK RELA â—¼   PHOSPHORYLATION ✅ + 0.85 0.85 Signor 10521409
ABCD1 ABCD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22939629 10551832
NR1I3 RXRA â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
TP53 WT1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
IKBKG RELA â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 15489227
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
NR1I3 RXRA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 8114692 12130689 15888456 19682433
AR SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AHR ESR1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PTGS2 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RELA SP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CHUK RELA â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CEBPB CEBPG â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12177065 20102225
ESR1 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 28065597 20935677 11887937 17284441
SP1 NFKB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18083845 16740634 33572115 7933095
NR0B2 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9773978 11861507
NR1H4 RXRA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 7760852 19883617
IKBKB RELA â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
SCT SCTR â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
SP1 JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25879517 10506225 16713569 33572115 16478997 17215518
JUN ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17317669 11477071 16713569 23747343
SP1 RXRA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18270252 10361124 10393239 16713569
AHR ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15837795 19460354 12612060 27420286 17392787 10620335 9611253
ESR1 SP3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10816575 16651265 31527615
NR0B2 RXRA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12198243 16189514 21988832 10594021
DNAJB11 HSPA5 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
IKBKG TNF â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
NR1H4 RXRA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
PLAGL1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18663001 22001409 18644983
CEBPG CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10982390 9442037 15041706
EWSR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12560328 18757425 20153576
CEBPG ABCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2404278 16132117 12526103
RELA EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17881446 23379415
IKBKG IKBKB â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 8209688 506093200 16126728
IKBKG RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15489227
TP53 MLH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18431400 15781865
PURA AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19790234 18413735
TAP2 TAP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 11133832 12213826 19297616 11381133 17055437 26789246 33961781 16828748 18802093 30833792 19201886
TP53 ID4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19500415 19783986 21293053
TP53 GGH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
TP53 TYMS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21351099 9260894
TP53 ABCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11483599 10792001 9865734
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
TP53 NME1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12669312 16440314
TP53 PLAGL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18431400 11360197
PDIA4 PPIB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 34079125 24981860 22665516 30021884
GNAS ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690
GNAS ADCY8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
GNAS ADCY9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
GNAS ADCY7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
JUN NR0B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15292277 12842887 19322021
JUN SLC10A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24309182 16890608 12454857
JUN NTRK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15870692
RELA WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9572484 11243407
RELA AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16713569 8798655
SP1 CYP3A5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11485307
SP1 SLC19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15652157
SP1 UGT1A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19546240
SP1 CA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8621466 22564704 21130740
SP1 DCK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14514691 20544528
SP1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20427719 20538607 9151857
SP1 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15100175 11495920
SP1 NTRK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19656944 19643914 21123453
SP1 ABCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9865734 23765166
SP1 EPHX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315822
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
AR PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18386814 16317058
NFKB1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18234965 12527911 19763573
NFKB1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9572484 11243407
CEBPB ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31527615 16651265 7651415 19652226 9817600
CEBPB CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15778453
ESR1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11457657 10949931 17068199
SP3 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9415398 11578973 11562358
ESR1 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15358113 15499176 18299335
ESR1 ABCB10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ESR1 TYMS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10875244
RXRA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
ESR1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
AR CYP3A5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17116727
NR1H4 SLC51B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16251721 16357058 17177110
NR1H4 ABCC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22291955 21296199
NR1H4 ABCB4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14527955 20422497
NR1H4 UGT2B4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12806625
NR1H4 NR1I2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16682417 21476904
NR1H4 SLC51A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19059462 16357058 17177110
NR1I2 ABCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16620787 19593667 12695338
NR1I2 SLCO1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11901222 12490595 12695338
NR1I3 ABCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15833929 11752103 12695338
NR1I3 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16006237 18334180 23934188
RXRA NR0B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23546875 19111018 15202934
ABCG8 ABCG5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12208867 16870176 27144356
SP3 SCT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15118068
NR0B2 SLC10A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12456679 15591588 15239098
NR0B2 SLC10A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11438503 14701722 16123152
SP3 SLC2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10556032 11689000 14644496
SP3 EPHX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315822
SP3 CYP3A5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11485307
SP3 SCTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14645499
SP3 DCK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14514691
SP3 ABCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11846400 10556032 16132117
SP3 ABCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15922656 10884428
SP3 PCYT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12584202 10744779
WT1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10392899 10860921 11734301
PLAGL1 ABCC6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18850323
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
TOP2B TOP2A â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 8710863 22939629
ADCY9 GNAS â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
HSPA5 HYOU1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
ATP1A1 FXYD2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ABCG5 ABCG8 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
IKBKB NFKB1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
CHUK NFKB1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CDKN1A TP53 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
TAP1 TAP2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
NR1I2 RXRA â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
ATP1A1 ATP1B1 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
IKBKG IKBKB â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5219009 16938294
IKBKB IKBKG â—¼   PHOSPHORYLATION ✅ 0.98 0.98 mint 8209688 16126728 506093200
CHUK IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
IKBKB IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
WT1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10224085 18202757 17160023
SP3 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 10649433 12434298 18850004 7499379 10625687 11064455 23401853 16103879 19584258 12151347 20301197 19197985 15790310 12773551 8995437 10485470 23676218 12379120 18628250 16810128 16533812 23066038 9819384 10321829
TP53 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 389.0 1.0 Omnipath 9349504 22270849 8749722 21242964 22290440 23874636 23349794 23650552 17280505 16288208 19882681 22948151 8641969 18840648 7777546 9360984 9707425 14614448 15586362 12889596 10597242 18719376 17938176 16343438 9916993 12806965 15024021 10037739 19394332 19749793 22480684 15136035 19501055 22732402 15988033 17307334 18272192 23665236 20331637 10435630 12239594 14743206 24599959 9714336 9652736 19954840 12392301 15339933 9154806 19383287 21295542 16894028 23187802 15248906 14522900 18483411 16261158 11892838 20190809 17167174 18615633 15790310 17916908 19472317 12717415 19789303 16317118 7696178 24584189 22989750 18573881 22532570 9288775 16103882 11890931 17646389 17344317 10753197 8557703 15872011 24356969 11278953 22279545 12902982 9920903 18644983 21524151 16540664 10935506 16537920 19843844 9535786 17878219 9405685 10749849 18656471 11021966 19723072 16778363 18628250 16557594 9614553 21791610 10072388 12203124 12420214 12640112 16601686 20531308 15741235 17317670 18446786 18505818 9224526 17569660 21900401 14517211 12934105 22713239 11313928 15492238 17509529 15985438 14722112 18755897 15489892 23759594 7624148 17786325 9223430 24074410 9525742 11395510 21317932 11444825 18645021 15856024 10559267 18593586 16970927 12665570 10101800 23017582 20696891 9268733 22001409 24821728 23146670 22427654 12573582 19118657 11973611 24096481 20797428 17685229 23066038 10029406 12681065 12433990 18769160 15208672 11152513 8547219 15851483 23474493 24384472 11175333 17158927 23100276 17762884 18951877 12045203 15051477 16107883 18521083 23159636 8603071 20814747 15082782 11375890 21084835 10348346 22244155 21325288 12379483 14580351 17592775 8910340 15566940 12173040 12007564 12609999 8878553 12080472 12384701 22266868 17404570 23329847 7478511 15067082 15007388 16458891 9268365 15728246 17224908 10094833 15897882 18059034 11739748 7624134 17146435 18690848 21528307 21546904 18208621 18172861 17977830 17721438 20817677 22894933 18225552 21642427 11162600 9183012 8647846 10660101 21858218 22514644 18451802 11384995 20673369 7774811 20187950 16230382 17339230 12168779 19630958 8242752 9895308 21606339 11748232 16410722 22611192 16061648 15009091 22503977 8799837 15660129 20473858 20448457 16488074 14612423 21903579 11668476 11313463 17101782 19067706 17121856 10792001 16341121 12925527 7566157 22190353 12782287 9233781 15509808 21245169 17145718 24134839 10498892 18094076 14635196 23208500 20843368 10327058 21969549 9440695 10625687 20885946 12851404 19846554 10910098 14614455 18419600 21552844 24835508 21541551 9472102 11922774 19244234 17903248 9216067 18193090 10566557 18757425 11429705 19608464 8632901 8691637 15184659 12716906 15259070 24559687 7970699 15738655 9588214 16574813 15302882 12560513 16131836 16778203 10522058 11032828 9816111 9108440 15860260 17108107 25024194 9582019 22266186 20036872 9926942 15710329 19243472 17997002 19435914 21093383 23149933 11162506 17678435 11895854 8616838 12748190 17610896 18269916 22086179 21557991 17942917 24821727 11557753 16204065 18645003 24205274 9816061 12226108 24379401 15539944 7753560 15371422 10799578 10777217 16434701 17996705 21957244 9191059 9519881 9207798 24289924 21733196 15496412 20124454 20153576 22172947 10321740 21715977 22253232 8816885 24189165 15882981 8752276 20511722 11514734 20962589 12869419 16733561 19713748 16931520 10499591 16581545 19738071
AR CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16281084 10076995 11606392 10606230 20610535 10809237
NR0B2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14752053 11502738 17074765 19322021
RELA CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18954936 22305266 23037503 18269916
CEBPB CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10982390 15466360 15041706
ESR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15557281 16628468 20696891 16847062 12151347 11517191 15378598 11274368 16469747 17681750 20301197 22787161 23349794
JUN CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11136975 12717415 21278055 10506225 19628677 12054510 18094076 10072388 18210215 10733944
SP1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 9580699 15978937 15557281 11064455 16103879 19584258 20301197 20935676 15961274 15361832 11274368 11842244 15489892 15302882 10212208 12796485 23184467 14529564 12806965 9819384 10321829 10649433 12434298 18270969 18850004 16081043 9183012 21858218 10809237 9618481 16298343 11574165 10362258 11384995 15659839 14744793 10030670 17090534 10733944 19318349 12665570 18202149 17516505 15033443 22001409 17885207 10485470 9553133 15345676 15694838 22427654 17556661 10506225 23066038 15979845 18636159 14527674 24821727 15899840 14755691 12151347 24589735 18210215 23877711 11953011 21311948 15528212 15790310 10878024 22132221 12782287 12773551 8995437 21184768 12379120 17026958 24451377 10601254 8557703 16810128 16533812 7499379 10625687 15389873 16706751 12727210 21325288 16818630 18419600 15041706 23235480 19244234 15694666 23329847 18509005
TP53 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19922265 12897156 19597488 16616141 28433629 20066118 20457558 19749794 6396087 21163364 17371838 21900206 21340684 25241761 12897801 12748190 20182602 11896572
SP1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17026958 9389648 9618481 17550342 12545156 11013220 15155580 11074002
CEBPG TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12177065 8258705 15187114 9916895 8726660 15284209 14572618 15850785 18438857 12571239
CEBPG ALB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 1592265 2227417 2558052 7619063 16608438 2357969 8102976 1840554 19087426 10542249
CEBPG IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9916895 10841183 18247123 19806478 11474579 8999951 18438857
CEBPG PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18362203 15221958 11673276 10692422 17524357 16256955 11522796 16399783 21104307 11133817
CEBPG IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 12177065 22389450 9655919 12219016 15389813 9621116 12200447 14754879 9950766 12626566 15158360 22558159 14600152 16798734 12215492 12115737 19782405
PTGS2 EGFR â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18633355 20138012 21847358 23010081 23390297 25987127
JUN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16170369 23455325 15923621 16423552 10803405 18604200
WT1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19014381 8827073 19321755 20944147 11071895 9291179 7588596
AR EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15305378 19318561 21613411 19258514 15650253 17242169 18692155 15288768 11556855 20610535
NFKB1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14678988 18367518 12469217 17881446
TP53 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20190820 18359760 9664135 10029407 8152794 11713584 8887630 9285564 19597475 11546792 1586628 18604200 18391986
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
SP1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 1282800 17616668 18575762 19538880 15665278 18202149 20435036 21705183 18007664 21464950 23821666 15533438 9819401 10830317 8393457 16087726 20407012 18391986
AR EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18358509 12534934 22260327 15288768 18951974
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
IKBKG CHUK â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IKBKG CHUK â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
RELA IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
NFKB1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
TNF IKBKG â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
IKBKG RELA â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 11280761 11438547 11460167 12133805 12811837 14660645 15145317 15199157 15485931 15536066 15573129 16818229 16970925 17237376 17254973 17301840 17363905 17485448 17693255 18264787 18716620 19833085 20138012 20300203 21133840 21217011 21232017 21807870 22435554 23086447 23422957 23430059 24378531 24699077 24766893 24958845 2649237 28462531
TNF IKBKG â—¼   DOWN_REGULATES ✅ - 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
IKBKG IL6 â—¼   DOWN_REGULATES ✅ - 38.0 1.0 ACSN 10542212 10754326 10952726 11875494 12133805 12907458 14660645 15199157 15465827 15485931 15536066 15644117 15749903 16243976 16413922 16818229 16878026 16970925 17237376 17254973 17363905 17404308 17485448 17693255 18716620 20138012 20300203 21217011 21807870 22435554 23086447 23390297 23422957 23430059 2649237 28462531 7594497 9743347
NFKB1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14743216
IKBKG IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 150.0 1.0 Omnipath 17145710 16938294 20932476 35339487 18266324 16260493 27929056 25979343 19666608 26496610 12133833 12192055 9751060 21423167 19706536 15836773 17561400 22099304 23986494 19959994 15327770 25400026 24266532 18450452 12657630 20434986 11583588 20200955 20300203 21903422 22990857 14743216 20167598 20098747 16126728 19656241 25852190 16906147 10195894 17000764 18329793 16186825 16547522 16611882 18037881 10968790 16497931 25286246 18462684 18207244 16603398 17965022 17977820 24240172 17568778 15084594 16129692 23506214 16319058 23123196 18949366 15218526 22605335 20368414 10837071 19820708 10980203 23131831 17363973 15214841 25304104 16493424 15184390 15691841 11864612 15802604 17693255 21455180 11865184 20211142 11971985 16970925 24469399 24618592 12486103 11057907 24369075 19365808 18583959 27426725 12612076 19422324 10094049 23109003 21803029 12459277 21640763 16285893 18266467 12709429 15620648 17072322 19815509 15749833
IKBKG CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17145710 17485448 16938294 11865184 11877453 16970925 22435554 17244613 17568778 17363905 16818229 15084594 15485931 24369075 20300203 21217011 12799363 23180781 14743216 16319058 21703539 19666608 20098747 12612076 16126728 15218526 23430059 9751060 20138012 18716620 20368414 10837071 25355947 15836773 23109003 20531300 17702576 17363973 15214841 12459277 17561400 21640763 16285893 28462531 12709429 10968790 15199157 26192618 12133805 16497931 11864612 17693255 17072322 11340079
IKBKG NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14743216
TAP2 TAP1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 10973281 11717192 14508489 16181333 17204652 22076556 22790179
TAP2 TAP1 â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 10973281 11717192 14508489 16181333 17204652 22076556 22790179
IL6 TNF â—¼   DOWN_REGULATES ✅ - 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
ESR1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23733894 15334655 16483936 12237295 20664923
SP1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 23733894 12759366 27030318 22534375 7649977 12509451 12378384 15175554 18357389 10829018 11390427 17897957 18218727 8258705 12560487 17047073 21320120 7918637 16847329 10559188 18930140 20068037 1618817 21784970 10688670 10913190 17307735 18467438 21411747 11500175 20221720 20701940
NFKB1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17513725 12058956 24337575 12657243 17704137 12471036 17707233 7624137 11259437 12686724 16433741 26114754 20237317 7876168 16707469 12117498 14976218 10485496 15465827 8622636 15812247 21138578 18990758 10748079 15013838 15749903 16916598 17646159 10754326 16040075 10837498 18285351 11675405 11739517 15743782 20066113 20617556 17085785 8530146 8805669 10919279 14960579 1740105 10963848 16055086 9742085 17292554 10553096 11312646 15543947 17442180 16285952 10079106 11297551 10551799 10201927 12907458 8679226 9281604 22782967 8219230 11749970 9916895 11094063 11490006 7895918 1618817 16483936 18057724 20722069 16569682 9452482 17407192 17082635
SP3 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14555463 12759366 19109523 11390427 11500175
AHR TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11470802 17588258 25690886 19703987 15627257 20181658
JUN TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 12759366 11087751 7935377 21059644 16881863 24548427 12509451 9826775 10318823 8998076 18408586 15546613 20164416 7896795 9211933 10952728 9566900 23583459 10748079 24009130 10954918 10754326 9813054 10837498 9988757 11739517 16365438 19285436 16199883 8816436 10551799 8552071 9160673 11490006 21098092 16483936 10688670 10913190 16888805 9030359 25567680 9760243
CEBPB TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 10775602 21059644 9831247 26114754 19530226 20220144 9566900 10748079 19489038 8726660 10754326 19109189 10838190 14514692 24012417 12184911 23971673 23590297 14976147 16850160 10629048 22074460 15850785 7929820 10887174
RELA TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 136.0 1.0 Omnipath 26596471 17707233 20817730 12686724 27075886 21765477 21537341 19530226 17390058 18077329 15064230 20617556 8805669 17351769 23335080 21573233 17292554 16285952 9916895 11749970 7895918 17496784 12628924 23857586 12657243 15857826 12471036 11259437 16433741 9831247 20237317 15465827 26023919 22661093 10748079 15013838 17350185 10754326 15470505 11827962 20139176 26408955 22901690 18772140 21108432 22742857 23195252 18362169 24012417 11312646 17442180 9281604 10079106 11297551 15081318 22718766 24908318 8219230 26004152 11094063 11490006 9916692 16483936 18057724 16569682 22138107 18467438 20547752 22723832 19846753 17407192 20221401 19854828 20534538 7876168 16707469 12117498 20544543 23178569 15812247 21138578 12610112 25888873 16916598 16040075 28039105 14749357 20066113 19285436 25161822 22388040 14960579 20195282 16199883 15543947 23971673 10551799 11290773 22798670 22021035 20722069 20221720 27338466 19385047 12058956 26997758 25690886 7624137 20686703 26114754 14976218 10485496 17607667 8622636 11007957 18285351 10837498 11739517 18719026 17268554 17085785 17142966 10963848 9742085 23042817 27534992 10553096 26516703 20696864 10201927 16850160 8679226 21098092 20097764 9129150 17082635
TNF RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 15192014 27329558 22240205 15833743 19351843 28187781 15841081 28107185 28373828 26999213 24386331 24957606 26179215 21572963 18258304 28317833 29441018 10722927 19596989 28423685 12881425 25118327 24036851 28089769 21904602 24141032 10938077 30201812 20691659 24166907 19789307 19393267 22768286 26310932 19411070 23789107 28790310 29708974 20507904
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
AHR TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17070097 15111621 11191113 20478272
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
NFKB1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10348347 11032029 8051093 12145335 20097177
JUN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22859294 17321721 20697347 10348347 12963547 10072388 22353755 18604200
CEBPB TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19135161 23564453 19075931 24333671
TP53 SLC2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 20729871 15059920 27692180 22483234 21862591 21394211
TP53 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 1346476 18234965 8554604 8898977 10745175 19714248 9988237 10029407 11096091 11172607 11920581 17952118 8679460 9112432 11350951 8502478 11483599 7949467
TP53 CHUK â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15469934 11557753 17434128
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
WT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16713569 10744705 8389468
TP53 PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21187340 16713569 11687965 21763744
GNAS ADCY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9228084 9395396 1719547 9268375 21406690
GNAS ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9228084 6935665 210183 17652154 2022671 21406690 32196115
GNAS ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9228084 9748257 9268375 21406690
IL6 CEBPB â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 11306493 15099563 15356132 15573129 18209571 18555777 18555778 19581928 20138012 23034983 23567181 24011634 24346288 25002027 25582338 26201938 26268945 27557510 7590867 8837607 9845545
RELA IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 114.0 1.0 Omnipath 26596471 19124729 10373597 9523851 23595969 28270510 21537341 17982049 15226358 18243142 12200447 20371366 24664372 23874122 14532843 18942706 10975857 21278793 10469356 22547075 17490702 11459775 23335080 10569191 19707556 19687301 7499267 8290595 23857586 24676671 18061164 11058167 12887736 15013753 15158360 22661093 20935672 20511231 17350185 10903137 16112536 27413250 21810609 16984731 16166627 18469854 12881425 24012417 23386688 22105366 8752656 12176740 27371733 22578249 18057724 20351184 10329846 19164127 10542237 11564778 20221401 15517885 19122653 20534538 7876168 27211851 9516466 18996370 8824277 18310089 21104991 25888873 12359431 11327783 20066113 20100571 19703987 19469019 21106671 16960103 18502099 16043358 21996739 20650996 22021035 11120852 12672795 12058956 18483242 22189669 14976218 17495236 11007957 21131967 11975924 27337441 9182853 10963848 17040605 11504280 15756023 10823821 17932106 19966855 20696864 12177065 8679226 9199307 17196927 20457835 21098092 17532054
AR IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12237244 8824277 19074897 11049111 17374439 11410519 20610535 19363165
JUN IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 26513016 10542237 21069809 15389813 15158360 20225236 12667961 20371366 20511231 20862675 8453101 10202034 18502099 10037779 8830832 19687301 21098092 25567680 20351184 17341596 11120852 21312239 24676671
CEBPB IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 8441418 10748205 21069809 1327803 7543095 11004486 9312180 23595969 15389813 12853840 7651415 7744000 9523851 19026986 17332680 8786324 8910763 11250916 23361365 11114305 7821611 21127061 9516466 10816606 1730090 8234276 15044620 9282937 16784777 20511231 1427600 24472318 7818522 10903137 23874122 8336793 22558159 14600152 19632992 9661072 14530280 1421375 11160296 9182853 22895549 25382637 9378980 9648065 24012417 11866474 8725624 12177065 8752656 11035101 18955501 2112087 15613028 9442386 9199508 7744784 15688424 8346247 22074460 17955490 12706815 11594800 11120852 10435001 8325885 19782405
NFKB1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 71.0 1.0 Omnipath 17513725 18061164 12058956 24337575 19124729 15611045 11058167 9523851 15517885 12887736 15158360 7876168 17495236 25549935 17982049 15241416 18243142 9516466 2405250 18996370 8824277 18310089 24664372 15749903 10903137 16112536 14532843 11327783 18942706 11975924 20066113 16984731 10975857 11160296 19703987 22895549 10963848 10469356 22547075 17040605 11459775 17490702 19469019 8247545 11504280 15756023 10569191 10823821 20696864 12907458 19707556 16043358 11035101 12176740 11302724 8679226 8725624 22578249 8752656 17196927 17532054 12727841 18057724 7499267 10329846 9199307 9502421 19164127 11120852 24676671 11098847
NR1H4 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19028791 18981289 19118524 19864602
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
SP1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20148354 8355696 8892460 1406636 19437621 9054614 17502875
JUN IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11306276 18566416 7935377 10226077 14686613 16365456 11145674 17283046 20463008 23608488 8133045 8798756 18789903 16729332
JUN PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 11901151 16001969 19783677 15238218 23523690 10668496 16007171 12057991 22472290 18294142 16339564 17556653 9830045 9988750 19825968 15994313 15772294 9620167 9686761 15525691 11356200 16256955 11234900 18097055 11980644 9705326 19522015 11278336 18282182 12086396 10811116 20237399
JUN ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 17283040 10369069 17452336 18213731 12907627 14612525 23678002
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
AR JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11577103 11518798 9211894 8798722 16713569 9591784 17721441
RELA JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18174238 9468519 16713569 10488148
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
CHUK RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
CHUK NFKB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
CHUK RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17145710 15611276 22110409 19609947 10521409 20863851 20051109 20363318 12767944 26999213 12842894 21903422 19110719 15858576 16382138 22155370 23894194 16046471 15128824 21569639 16846590 8246997 15485852 25341660 15494311 11983155 15980040 15489227 15849198 14636585 23343355
CHUK IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 91.0 1.0 Omnipath 9346484 24911653 20932476 28514442 11971985 16970925 12210728 9346485 17965022 16713569 12486103 9891086 15456791 11057907 20434986 16129692 16260493 21903422 21724995 16286467 14743216 16319058 18949366 10779355 25748427 25852190 12244103 11585904 9751060 15218526 10094049 10837071 9914500 21575199 9721103 25241761 10195894 9689078 15214841 21784860 17561400 21640763 16285893 10733566 16186825 16493424 10022904 12709429 12351658 10968790 12547194 15691841 15620648 15327770 11864612 11460167 14636585 17693255 17072322 9346241
CHUK NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 12482991 19442713 14743216 15494311 11976329 15489227 16382138 16713569 10022904 10469655 27554194 11158290 11297557
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
PRKACB RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
PRKACA RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
IKBKB RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
PRKACG RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
SP1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7636984 8450395 9151857 20538607 11964305
RELA AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24466341 16619263 14576180 15517885 14715080
RELA IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 26596471 27338466 11114294 8413223 20975042 17707233 23383347 11058167 12686724 16433741 23667107 15382119 19122653 24009751 27211851 18566416 15292915 20617571 23056550 12517972 18285351 19843519 22267743 15812237 25161822 22388040 8021507 9878621 14960579 10963848 23195252 11395507 27534992 9058643 15543947 19846753 20696864 8679226 24908318 28389361 27371733 15972680 20336759 10080875 17082635
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
RELA PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 16001969 9266823 19783677 12471036 17673602 10827178 16210649 20669087 12466023 15517885 15013753 12622742 20600530 14645117 18294142 19618291 12067569 15655349 17556653 18973191 14988266 12871860 20103608 19284764 15555528 21149600 11082190 15234907 9041934 22001128 16820889 18752821 19766095 15997464 8995303 9710122 12349897 15387324 15368354 18057724 15547942 16624933 17767925
RELA ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18234965 21054339 19763573 12527911 22927901 10026303
RELA CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19002106 16608838
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
IKBKB RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 135.0 1.0 Omnipath 15280197 17785205 27329558 22110409 22753932 22205033 21765477 15611068 18519641 15858576 25241761 33579825 23536830 28122346 19393267 34556881 24442433 14560022 15192014 21242976 16840782 19609947 33789981 10521409 26826124 21492457 19110719 23303310 16105840 22212641 26587973 34219129 15210811 16046471 11359840 27626700 15128824 28416608 17178723 21674813 17362989 28737909 19377466 15980040 16407239 15849198 20507904 26082493 15557193 34082140 21798539 26267322 29363544 12767944 20224721 26307684 12842894 17108032 26170389 24336331 27315556 31980577 11259436 34380537 20872791 21674474 15465828 15994321 17548605 26603838 16148147 25136068 33914760 26569329 22234699 17012367 14636585 22039465 32123095 15212693 27466442 33883226 15611276 22081069 19197368 17070014 20051109 26693062 14963024 33971703 28381553 33459422 27244888 18544167 18922932 20188669 15485852 20696864 22689577 17982102 20410276 15489227
PRKACA RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 11931769 15833743 9150141 17959673 9660950 16135789 12628924
IL1B RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25606026 26999213 22240205 23666959 19197368 25306394 24009751
RELA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12055073 7933095 10671503 20861353
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
SP1 SCT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17875929 15118068
SP1 MPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12057865 17521322 8662930
SP1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8864062 16928829 16704988 23662037 10773882 9353275 15661808 17984071 18430409 22347450 20739403 8994183
SP1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16840740 17616668 17012241 15767339 23635401 10825178
SP1 LDLR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 24358207 14568562 7836375 11250935 10894816 9610768 11792717 16647292 7597088 14998783 7627719 10841543 16303770 9271397 10224053 16449644
SP1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18234965 7565762 10411657 23133566 10860921 9458366 17363581 7621073 8103518 10644769
SP1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12759366 16574895 16790435 9458366 9415398 12169688 10949931 12694408 11562358
SP1 SLC9A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12464626 16464174 19064501 16760259 21600882 19303862 11841999 17540780
SP1 DHFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9363748 1834700 8552092 1597451 8622648 9591776 9819401 11389717 11158299 1740417 1820211 12788094 3945313
SP1 AHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9778040 16410262 21569840 20478378
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 PCYT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10216289 12794070 16484221 20096375 10744779 17384411 16157598 15247247
SP1 SCTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23168245 14645499
SP1 TYMS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10875244 9218479 11855856
SP1 UGT1A6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15933209
SP1 ALOX12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16478997 9164849 18590721 10973489 20508969 14518567 16118214
SP1 ABCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17272513 22105759 24069312 16132117 11846400 10772892
NFKB1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 8413223 17707233 11058167 12686724 16433741 18285351 8021507 9878621 14960579 10963848 9058643 15543947 20696864 8679226 11035101 15972680 20336759 18772363 10080875 17082635
CEBPB IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 21917825 12072435 9372929 16867259 20702408 17283046 10464291 16569740 10801783 15812237 22260630 10841183 10838190 10383163 9376596 17386941 10956548 12759449 11278846 12468538 11035101 11801594 2112087 12355443 15383601 16439360 19806478 22074460 16399630
NFKB1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 9266823 20669087 12471036 17673602 10827178 16210649 12466023 15517885 12622742 18294142 19618291 12067569 15655349 17556653 9988750 18973191 14988266 12871860 20103608 15555528 11082190 15234907 22001128 16820889 19766095 15997464 12349897 15387324 15368354 18057724 15547942 16624933 17767925
SP3 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16840740 17616668 10825178 17012241
AHR PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18001219 12548657 15213229 19056653
CEBPB PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 7559624 11259631 18367585 11095928 14966110 12914528 15221958 18294142 11668179 17556653 10652293 21150337 20506344 18820298 18650268 16786175 10631313 10841183 22369775 19908286 16820889 11522796 15713664 16699180 16399783 10956548 11278846 10724331 16981245 18444174 14645533 16452236 12086405
IKBKB NFKB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
PRKACA NFKB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
NFKB1 PRKACB â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
NFKB1 PRKACG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
NFKB1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14576180 15517885 20159994 12165860 16619263
IKBKB NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 57.0 1.0 Omnipath 31598684 11976329 16713569 10469655 29485707 26999213 12842894 10835356 27187478 27402796 18782567 27554194 12482991 25241761 10022904 15199157 19519322 15489227 19250910 15212693 11158290 11297557
PRKACA NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19531803 12947093 17959673 15642694 15197457
ESR1 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19652226 18414489
CEBPB LDLR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12235180 16563127 19804198 12947119
CEBPB SLC19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15652157
CEBPB ALB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8040336 16608438 1487491 20529675 19932685 1840554 8703043 10542249
CEBPB ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9040943 15044620 7961962 9712708
PRKACA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 28003367 23060444 25867080 21455600 30600261 1716180 28242698 19328185 32102849 92316961 19095655 14602047 7530719 10581361 11053017 9385646 25330774 15657296 1377674
AR PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12933667 10075669 9886819 15691881
PRKACA WT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9366517 11237525
PRKACA KCNN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16513649
PRKACA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22266331 9891036 15193262
PRKACA ABCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12196520
PRKACA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11162439
PRKACA HMGCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 2369897
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
ESR1 UGT1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10854430 23714156 9773976 12114525
ESR1 ABCG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20705611 10342828 23592396 22098950 14973083 15695404 19967559 17878748 24103091
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
NR0B2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 21071413 9773978 18988627 11861507
AHR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12612060 17392787 10620335
NR0B2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 16713569 11735420
AHR UGT1A6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9466822 9762354 19525444 8068691 11368516 19831498
RXRA NR1H4 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11387316 12815072 10334992 16908160 11870371 10334993 16541101
NR1H4 NR0B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15817812 11705994 15692145 18842595 22345554 23546875 11030332 20185821 24498423 22683342 23607861 11518759
NR1H4 ABCB11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18270374 15471871 16819395 17135343 12135489 16371446 23546875 22345554 11387316 18668687 19833092 12052824 11870371
RXRA NR1H4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 19883617 7760852 10744760
NR1I3 NR1I2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10924340 15557560 14683479 22363234
NR1I2 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 18805405 17526937 15499176 18299335 20538721 15367577 18096673 12542705 15269186 10935643 18784074 11329060 12417264 16013442 11602528 19171678 16455805 19077665 19934400 23732298 23807564 23928187 23891548 21920351 17293382 11991950 9727070 15180306 15698577 17764444 21292004 11602521 11336976 12781341 12606758 10403778 12167569 19712670 12664659 22982774 21311750 20736322 16219912 21342487 21733184 19129222 19138736 19232333 23179081 22976785 19686701 15650019 11581012 23536728 12130689 12601364 15523048 16608838 17035600 12072427 17429319 10570062 18332045 12851153 10772626 11114890 20171174 15100175 12514743 10611146 20942813 19074998 18540626
NR1I2 ABCC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21733184 24498169 11836020 11706036
NR1I2 SULT2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17687072 14978251 17595319 15541768
NR1I2 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15629111 15322103 15331348
NR0B2 NR1I2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12805410 23331499 16455805
NR1I2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 9727070 15604093 11706036 9489701 16189514 26855179 23160820 22976785
NR1I3 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20580705 18805405 12130689 15698577 18677425 20642445 11114890 12167569 12514743 15990349 12664659 19686701 22363234
NR1I3 UGT1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12114525 15557560 11343253 19541828 18172616
NR1I3 ABCC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24498169 15833929 18334180 11706036
NR0B2 NR1I3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 14963109 8650544 9773978 15000748
NR1I3 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8114692 23331499 12130689 12896978
RXRA ABCB11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23546875 11387316
RXRA CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19106115 20338915 16049268
RXRA CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19712670 18400206 16608838
NR0B2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 23331499 16189514 12198243 10594021
CA2 SLC9A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12138085 16189514 16475831
SCT SCTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 7612008 7782300 9440501 8579602
NR0B2 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 19346330 15314177 23038264 21566081 18323469 19805516 11030332 20375098 15358835 15817812 21817852 12525500 21963511 17145766 17654698 19085950 19056864 16049268 15581596 11518759
SP3 SLC9A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12464626 16464174 16760259 19303862 17344314 19064501 17540780