ABL1
|
GTF3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
JUN
|
ABL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9746785
15145216
|
ABL1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11753601
9916993
|
CDKN2A
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19049976
|
TP53
|
BCL2L11
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19427386
20124456
|
CDKN1A
|
CCND3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
AKT1
|
CDKN1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12244303
11231573
|
NOTCH1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11306509
14670925
|
MEF2D
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24390737
24279793
|
CDKN1A
|
TP53
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16616141
5218511
|
AR
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10076995
|
PPARG
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15041706
|
TGFB1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23741479
12058028
|
AKT1
|
CDKN1B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12244303
11231573
|
PPARG
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11034103
15763423
|
CDKN2A
|
CDK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15232106
5217098
|
YY1
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22025288
18558095
|
TP53
|
HMOX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24366007
21552291
|
TFAP2A
|
HMOX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8016102
|
LYN
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
LYN
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218167
16374509
|
DUSP1
|
MAPK12
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11062068
11359773
|
MAPK12
|
MEF2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9858528
10849446
|
TP53
|
MSH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12209975
|
TP53
|
NCOA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19433796
0902873106
|
TP53
|
PLK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11447225
11551930
|
TP53
|
PLK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21394211
16581545
|
PRKDC
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CSNK2A1
|
PRKDC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20711232
|
TERT
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18775701
6742757
|
TFAP2A
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19701232
18754863
|
SPI1
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17967894
7988559
|
PPARG
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16556873
19912441
|
AR
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19481544
7103716
|
TP53
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11350971
10984493
|
TP53
|
TMSB4X
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
TP53
|
CSNK2A1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12393879
11239457
|
YBX1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12835324
16963428
|
TP53
|
HLA-A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15501971
12857899
|
TP53
|
IFNA13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19416861
22509910
|
TP53
|
TFAP2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18980971
16636674
|
TP53
|
IFNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17564708
24180280
|
TP53
|
CAT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15059885
18487368
|
TP53
|
NFKBIA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10698490
12700242
|
TP53
|
TCF7L2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
14990988
|
TP53
|
YBX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18504427
22417301
|
TP53
|
TH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16133124
19618851
|
TP53
|
FASLG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10969818
|
TP53
|
DUSP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12890671
|
TP53
|
CRYZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
MMP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
LIF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
YBX1
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17893273
18800033
|
YBX1
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12446674
8163940
|
YY1
|
PRDX3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22951020
|
YY1
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7838721
8524292
|
YY1
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24369345
|
FGF9
|
FGF10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
8663044
|
JUN
|
COL1A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8621730
12384935
|
MYB
|
COL1A2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9989795
|
ETS1
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22869003
20428211
|
ETS1
|
IL10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22266280
17376198
|
CEBPA
|
IL10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12219016
12493739
|
JUN
|
KRT16
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12954631
16214953
|
JUN
|
CCL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19299558
18789903
|
MAP3K1
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9689078
16681998
|
NR1H3
|
FGF21
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21889884
23073827
|
SMAD7
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15855641
20631490
|
SYK
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9830044
9396765
|
CD3G
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3E
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3D
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
SMAD7
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10519551
19758997
|
SMAD7
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15632190
14761601
|
SMAD7
|
KRT5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23475202
17499880
|
SMAD7
|
TGFB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15855641
19385040
|
TCF7
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19648923
26714756
|
PPARG
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19160541
15187132
|
ELK1
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19554388
18240315
|
MMP1
|
MMP9
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7780967
1371271
|
ARNT
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20511231
21104991
|
HES1
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18976936
25733872
|
TFAP2A
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16616959
9480831
|
PTEN
|
CSNK2A1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12297295
11035045
|
PTEN
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10644997
|
TGFB1
|
NOS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10362813
|
TGFB1
|
SPARC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16189514
15034927
|
AR
|
NOTCH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22347519
23145211
|
NOTCH1
|
HEY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21828089
14976548
|
HRAS
|
FOSL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TCF7L2
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16132617
12200448
|
JUN
|
MAPK9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18793328
10871633
|
TCF7L2
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
|
JUN
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12832543
11192249
|
JUN
|
AFP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1708774
7537266
|
JUN
|
DUSP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20702711
19585511
|
JUN
|
MGP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11425864
|
JUN
|
HRK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19304750
17428807
|
JUN
|
ACHE
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8382609
22243239
|
JUN
|
IL13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21989417
15494506
|
JUN
|
VEGFD
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23157741
19136250
|
JUN
|
LPL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
|
JUN
|
SELE
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9103451
9317150
|
JUN
|
IL2RA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14660657
7889400
|
JUN
|
HEY1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12384550
15314183
|
JUN
|
LBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15114678
|
MAPK9
|
JUN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19527717
7148309
|
HES1
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14614508
|
PPARG
|
STAR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19698295
19272380
|
PPARG
|
IVL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18077140
17330131
|
PPARG
|
IFNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
21148557
21571064
|
PPARG
|
TLR4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19846417
18846339
|
PPARG
|
FABP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17826730
15687259
|
PPARG
|
IL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19307774
11093153
|
PPARG
|
IL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19217272
14573767
|
PPARG
|
FABP4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20592862
|
PPARG
|
GSTA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15150131
|
PPARG
|
NR1H3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
15722453
|
PPARG
|
NOS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10848596
|
SPI1
|
CEBPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8695841
22474248
|
SPI1
|
IL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19487701
|
SPI1
|
MYB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9292515
12027437
|
SPI1
|
CSF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15676205
|
IL2RA
|
IL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0607058103
17032757
|
MEF2A
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17559812
14722108
|
TCF7
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
2088505
23954131
|
MYB
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1349016
11486019
|
FOSB
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7989759
9171236
|
FOSL1
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
1737937
11385624
|
AR
|
IL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20610535
23554843
|
GATA1
|
IL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15739164
21454593
|
GATA1
|
IL13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15229217
15494506
|
CEBPA
|
IL3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10453008
|
ILK
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11507039
19460343
|
ILK
|
SPARC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16115889
|
ETS1
|
TIMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10051488
8557686
|
ETS1
|
CD3D
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12324448
|
ETS1
|
CD8A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8413295
|
ETS1
|
NOS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11768239
12896968
|
FGF2
|
FGF9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18552176
18757403
|
FGF2
|
FGF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18552176
18757403
|
AR
|
FGF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11690559
20610535
|
FGF2
|
GJA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23882217
20338032
|
CEBPA
|
CDK4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11867521
11684017
|
CDK4
|
MEF2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
21902831
25733682
|
ELK1
|
FOSL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15806162
17082637
|
ELK1
|
UBE2I
|
â—¼ SUMOYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
17036045
5219211
|
MYB
|
CEBPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10706719
|
CEBPA
|
FABP4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15110775
15158467
|
CEBPA
|
KLK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16455820
16774685
|
CEBPA
|
IL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10453008
|
ETV1
|
MMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14550555
11593430
|
AKT2
|
GSK3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9065430
16023596
|
MEF2D
|
MEF2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8798771
9858528
|
MYB
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12096342
18945670
|
AR
|
TMSB4X
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20610535
17916567
|
AR
|
HEY1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20610535
15684393
|
AR
|
ADM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16376459
20610535
|
AR
|
MMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17636177
8798622
|
AR
|
MT2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17721441
|
AR
|
FGF8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12140757
|
AR
|
MMP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16888681
|
NR1H3
|
APOA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17026988
11035776
|
CD3D
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3D
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3E
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
MMP2
|
DCN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9148753
|
TCF7
|
LEF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
32448362
25921273
|
LEF1
|
MMP13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17971297
19783677
|
TCF7L2
|
NOS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16849547
11935128
|
TCF7L2
|
TCF7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15473860
10489374
|
IL23A
|
IL12B
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
FGF6
|
FGF9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18552176
18757403
|
F2RL1
|
HMOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
TFAP2A
|
IVL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12192491
9219563
|
TFAP2A
|
KRT5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12024040
|
HSD17B4
|
COL6A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
TGFB1
|
MMP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
16189514
25241761
10652271
|
GATA1
|
SPI1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
10364157
12202480
|
SMAD7
|
LEF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
15750622
15684397
|
FGF1
|
SDC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
AKT3
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
MEF2B
|
MEF2D
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
MEF2B
|
MEF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
FGF9
|
FGF20
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
TP53
|
YBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
CDK3
|
AKT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CCR5
|
CCL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
9334377
10477718
10498628
8663314
23597562
12427015
9468473
|
AKT1
|
CDKN1A
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
31575057
|
PGF
|
VEGFA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
830.0
|
0.83
|
STRING
|
36370105
|
CD247
|
CD3D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
CD3D
|
CD3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
AKT1
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28628118
24412244
28205554
|
TGFB2
|
TGFB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
27684187
11483955
33961781
11157754
|
AKT1
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
18423396
|
CDK3
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
APOA1
|
APOA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
10722751
24981860
3104518
|
VEGFB
|
VEGFA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
25241761
8702615
33961781
26186194
|
SPI1
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12091339
9681824
|
AKT2
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
12149249
9736715
12176337
11445557
33961781
14500673
11278835
11546794
|
AKT1
|
ARNT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
15833858
28628118
28205554
|
CD8A
|
CD8B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
PTEN
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
AKT1
|
PTEN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
ACTA1
|
UTRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
855.0
|
0.85
|
STRING
|
36370105
|
AKT1
|
PTEN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
12297295
19903340
12077256
28628118
20605778
28205554
10866658
20596030
|
HEY1
|
HES1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
27129302
26068074
19802006
33961781
|
SPI1
|
CEBPA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16983342
12091339
|
IL2RA
|
IL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17032757
16477002
1993646
|
AKT1
|
NOS3
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
24379783
|
DCN
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
MAPK9
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
9405416
|
LYN
|
BTK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11226282
8058772
11598012
8629002
8630736
|
NCOA6
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10823961
12519782
|
CCR5
|
CCL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9334377
10477718
9169459
11700073
9468473
|
MMP9
|
TIMP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
24330623
33961781
|
MMP1
|
TIMP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
TIMP1
|
MMP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16189514
9063449
|
AKT1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
BCL2L1
|
HRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CSNK2A1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
AKT1
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
IL10
|
YY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
CCNA2
|
CDK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
8626584
33961781
26186194
23602568
|
NCOA6
|
PPARG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15604093
19596656
24368734
10788465
11877444
19047629
|
ILK
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
32707033
23455922
25852190
|
AKT1
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15678105
15262962
|
JUN
|
ETS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
20195357
8557686
|
ILK
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
12149249
9736715
12176337
11445557
18339839
11825911
11313365
14500673
11278835
11546794
|
FGF2
|
PTX3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
FGF2
|
SDC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
16982797
33961781
|
AKT1
|
NOS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
PRKDC
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
AR
|
KLK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
CD3D
|
CD3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
TERT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28628118
15843522
28205554
10224060
18775701
|
MEF2D
|
MEF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
8798771
33961781
25609649
9858528
20590529
|
KRT16
|
KRT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
CDKN2A
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
AR
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21310825
20610535
18196538
|
TMSB4X
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MSH2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CDKN1A
|
ANGPT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
ETS1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18955504
12740370
|
HES1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19541765
19321451
11809764
|
AR
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20610535
17522055
18687691
|
JUN
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10700231
20566634
19959471
|
LEF1
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19340300
|
ETV1
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19340300
|
AR
|
HMOX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11965035
20610535
|
TP53
|
MSH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11350971
8630028
|
NCOA6
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14645241
|
TERT
|
LEF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
19571879
11532957
21654818
|
TERT
|
TCF7L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
19571879
11532957
21654818
|
ETS1
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16556873
20842112
|
PPARG
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16887883
14960510
|
TP53
|
FGF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
8090761
10029407
|
TP53
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22804246
23666675
20406462
|
TP53
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15469934
14586398
|
YBX1
|
COL1A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12446674
12917425
16278212
|
YY1
|
NOS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19402223
20430007
|
ETS1
|
COL1A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16564026
24058639
11278621
|
GATA1
|
FCER1G
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16522818
15967781
24639354
|
PPARG
|
CCL2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
10432118
17681149
23390297
|
JUN
|
IL10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15699140
25567680
28100679
|
MEF2A
|
IL10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22578382
21454555
19058854
|
SYK
|
MS4A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
8071371
7528327
8910399
|
PPARG
|
CCL3
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
10432118
17681149
23390297
|
JUN
|
CCN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12939282
19126648
21029732
|
UBE2I
|
NR5A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15192092
15192080
21467194
|
MAP3K3
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14636585
10085062
|
PPARG
|
FGF21
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18467542
19906798
17954559
|
CD3G
|
SYK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
7517665
8657103
15161916
|
CD247
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9295038
7761456
7522230
|
AR
|
PLAU
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11676474
20610535
11745419
|
JUN
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15579469
10843994
|
NR1H3
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23686490
16484597
24438183
|
TIMP1
|
MMP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
24330623
19010413
|
CXCL8
|
MMP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18660381
17375198
11023497
|
MMP9
|
TIMP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
24330623
19010413
|
CCR5
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11449371
10477718
10488147
9334377
8663314
14637022
9207005
11116158
9289016
|
SPI1
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10760799
16707500
|
PPARG
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12909507
20663893
11932328
|
FOSL1
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19687301
20386569
11028561
|
HRAS
|
PAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15520807
17462920
20363321
|
HRAS
|
SDC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15752734
16997272
32196115
|
AR
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17617741
20610535
22040886
|
JUN
|
SPARC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11042689
7988564
12370830
|
JUN
|
ETS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
1945412
8247540
|
JUN
|
IL12A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16600913
22904313
|
JUN
|
ACTA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
1460048
|
SPI1
|
IFNA13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11244574
17108032
20585034
|
SPI1
|
FCER1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11971001
24639354
|
SPI1
|
MMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17030072
14688368
9178763
|
SPI1
|
IL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19592658
11150515
21957289
|
CD8A
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15136729
15534202
16551255
|
CD8B
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15136729
15534202
16551255
|
TFAP2A
|
ILK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19147542
19176380
24361375
|
TFAP2A
|
ETS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
1945412
8247540
|
ETS1
|
CSNK2A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10849443
19027835
|
ETS1
|
MYB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7848925
8999884
|
TCF7L2
|
PLAUR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19784072
|
PTX3
|
FGF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16020751
20363749
19627396
22267482
|
CDK4
|
CEBPA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11684017
11867521
15107404
|
AR
|
SENP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25014244
17932034
19116244
|
AR
|
ACTA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15623502
20610535
|
DUSP1
|
MAPK9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
8626452
11359773
|
LEF1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16741972
16474850
19351848
|
AR
|
FGF7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8580999
20610535
7522959
|
AR
|
TH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16356647
20610535
|
AR
|
IL12A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
26939703
23941877
20610535
|
AR
|
TCF7L2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12799378
20610535
|
FOSL1
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20353950
19289495
18288638
|
ARNT
|
UGT1A6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20854796
9466822
|
MMP1
|
MMP2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
8194591
7981201
8015608
|
TCF7
|
LEF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15473860
17335794
11326276
|
TCF7L2
|
FGF18
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14559787
17158875
|
AKT3
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24379783
|
IL23A
|
IL12B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29997244
12023369
11114383
18680750
|
IL12B
|
IL12A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10899108
10779781
7527811
|
AKT2
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24379783
|
TFAP2A
|
LPL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18948972
16890192
17549389
|
TFAP2A
|
TH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9751166
11146001
|
AKT1
|
GSK3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
FOSL1
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
CCND3
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
908.0
|
0.9
|
STRING
|
36370105
|
CCNA2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
TP53
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
CDK4
|
CDKN2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
CD247
|
CD3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
CDKN1B
|
CDK4
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
5219242
17053782
|
CCND3
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
CD3E
|
CD3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
B2M
|
CD8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
CD3G
|
CD3E
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
20890284
9582308
2138083
|
CD3E
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
JUN
|
FOSB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
29020630
33961781
25609649
|
IL12A
|
IL12B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
951.0
|
0.95
|
STRING
|
36370105
|
CDKN1B
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
34591612
|
CDKN1A
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
JUN
|
FOSL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
23661758
11912197
24029232
9160889
20511396
33961781
26258633
11708771
11431474
|
BCL2L1
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
CCL5
|
CCR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
IL12B
|
IL23A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
BCL2L1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
CDK4
|
CCND3
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
8153045
21516116
|
JUN
|
MAPK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CDK4
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
CDK4
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
CCNA2
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
B2M
|
HLA-A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
CCND3
|
CDK4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
16189514
25416956
21988832
33854235
9106657
14681455
21516116
23880157
16985050
32296183
10342870
26496610
19237555
9716181
11360184
30217970
15232106
14641107
25910212
27107012
16782892
33961781
26186194
11896535
|
CCND3
|
CDK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PAK2
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
23331499
18161990
20841568
11121037
|
LYN
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12644574
16787943
16912036
16076903
11847100
|
ABL1
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
12445832
15212693
12573241
8629002
17932028
10051622
25704810
8630736
34162728
9188445
16497976
20841568
27602755
11598012
9326643
|
ABL1
|
PRKDC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15686624
9109492
9295282
9312071
|
ABL1
|
MAP3K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20841568
10866655
|
ABL1
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
19818398
18619508
10637231
20841568
14757045
15302935
|
ABL1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17254966
17908796
22276948
16195327
|
ABL1
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
14757045
20841568
12167702
|
ABL1
|
TERT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
10837221
20841568
|
ABL1
|
CAT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
29535798
26375285
26117330
12950161
20841568
26340608
12777400
|
ABL1
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
30323259
25368164
26385316
|
TP53
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
22869582
9582400
9989972
11713584
18172861
23519249
12705879
9000137
11713302
|
GATA1
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17420275
10381501
|
HRK
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
17145710
9130713
16697956
21731739
15694340
10075695
14596824
15031724
|
AKT1
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
20138985
15169778
9812896
17680028
11756412
11923280
20214616
16697215
10949026
10722653
20832730
18570873
18372248
11715018
20398329
17052453
18636226
15808505
|
BCL2L11
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
34.0
|
1.0
|
Omnipath
|
17145710
16697956
9430630
17525735
22516262
18498746
10198631
21199865
20836993
26186194
15694340
17289999
27013495
32296183
23245996
11859372
19427863
21671007
14596824
9731710
16260615
|
TP53
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
24814347
12667443
16151013
26556313
14963330
16713569
20837658
24474649
21900206
|
PLK3
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21336504
21840391
|
BCL2L1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
24814347
12667443
16151013
26556313
14963330
16713569
20837658
24474649
21900206
|
JUN
|
BCL2L11
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17702754
16153157
23285061
22869147
21439021
|
MAPK9
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
15486195
14555991
18691976
18174237
12591950
15470142
12818176
|
AKT1
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
17145710
16282323
30923040
|
CDKN1A
|
CDK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
23443559
26186194
23602568
24218572
32296183
7626805
9811456
|
CDK3
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
26755651
19118012
|
CEBPA
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15466360
9442037
12502863
8846917
|
TFAP2A
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
21084835
9473523
16867219
16288208
11420667
18955504
20805990
8988173
17875680
12226108
|
TP53
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
389.0
|
1.0
|
Omnipath
|
9349504
22270849
8749722
21242964
22290440
23874636
23349794
23650552
17280505
16288208
19882681
22948151
8641969
18840648
7777546
9360984
9707425
14614448
15586362
12889596
10597242
18719376
17938176
16343438
9916993
12806965
15024021
10037739
19394332
19749793
22480684
15136035
19501055
22732402
15988033
17307334
18272192
23665236
20331637
10435630
12239594
14743206
24599959
9714336
9652736
19954840
12392301
15339933
9154806
19383287
21295542
16894028
23187802
15248906
14522900
18483411
16261158
11892838
20190809
17167174
18615633
15790310
17916908
19472317
12717415
19789303
16317118
7696178
24584189
22989750
18573881
22532570
9288775
16103882
11890931
17646389
17344317
10753197
8557703
15872011
24356969
11278953
22279545
12902982
9920903
18644983
21524151
16540664
10935506
16537920
19843844
9535786
17878219
9405685
10749849
18656471
11021966
19723072
16778363
18628250
16557594
9614553
21791610
10072388
12203124
12420214
12640112
16601686
20531308
15741235
17317670
18446786
18505818
9224526
17569660
21900401
14517211
12934105
22713239
11313928
15492238
17509529
15985438
14722112
18755897
15489892
23759594
7624148
17786325
9223430
24074410
9525742
11395510
21317932
11444825
18645021
15856024
10559267
18593586
16970927
12665570
10101800
23017582
20696891
9268733
22001409
24821728
23146670
22427654
12573582
19118657
11973611
24096481
20797428
17685229
23066038
10029406
12681065
12433990
18769160
15208672
11152513
8547219
15851483
23474493
24384472
11175333
17158927
23100276
17762884
18951877
12045203
15051477
16107883
18521083
23159636
8603071
20814747
15082782
11375890
21084835
10348346
22244155
21325288
12379483
14580351
17592775
8910340
15566940
12173040
12007564
12609999
8878553
12080472
12384701
22266868
17404570
23329847
7478511
15067082
15007388
16458891
9268365
15728246
17224908
10094833
15897882
18059034
11739748
7624134
17146435
18690848
21528307
21546904
18208621
18172861
17977830
17721438
20817677
22894933
18225552
21642427
11162600
9183012
8647846
10660101
21858218
22514644
18451802
11384995
20673369
7774811
20187950
16230382
17339230
12168779
19630958
8242752
9895308
21606339
11748232
16410722
22611192
16061648
15009091
22503977
8799837
15660129
20473858
20448457
16488074
14612423
21903579
11668476
11313463
17101782
19067706
17121856
10792001
16341121
12925527
7566157
22190353
12782287
9233781
15509808
21245169
17145718
24134839
10498892
18094076
14635196
23208500
20843368
10327058
21969549
9440695
10625687
20885946
12851404
19846554
10910098
14614455
18419600
21552844
24835508
21541551
9472102
11922774
19244234
17903248
9216067
18193090
10566557
18757425
11429705
19608464
8632901
8691637
15184659
12716906
15259070
24559687
7970699
15738655
9588214
16574813
15302882
12560513
16131836
16778203
10522058
11032828
9816111
9108440
15860260
17108107
25024194
9582019
22266186
20036872
9926942
15710329
19243472
17997002
19435914
21093383
23149933
11162506
17678435
11895854
8616838
12748190
17610896
18269916
22086179
21557991
17942917
24821727
11557753
16204065
18645003
24205274
9816061
12226108
24379401
15539944
7753560
15371422
10799578
10777217
16434701
17996705
21957244
9191059
9519881
9207798
24289924
21733196
15496412
20124454
20153576
22172947
10321740
21715977
22253232
8816885
24189165
15882981
8752276
20511722
11514734
20962589
12869419
16733561
19713748
16931520
10499591
16581545
19738071
|
AR
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16281084
10076995
11606392
10606230
20610535
10809237
|
SMAD7
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
10878024
15922743
20104486
12185267
15555279
11180003
|
JUN
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11136975
12717415
21278055
10506225
19628677
12054510
18094076
10072388
18210215
10733944
|
PPARG
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19551868
19103521
19208833
16985067
18509005
15041706
15345676
16091736
|
TP53
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
19922265
12897156
19597488
16616141
28433629
20066118
20457558
19749794
6396087
21163364
17371838
21900206
21340684
25241761
12897801
12748190
20182602
11896572
|
AKT3
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
12851486
15023346
19216069
17680028
11756412
16680151
20214616
11463845
23109003
20452955
9829964
20398329
17646672
10217147
|
AKT2
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
19216069
17680028
11756412
16680151
20214616
11463845
21933447
16982699
20452955
9829964
20398329
17646672
10217147
|
AKT1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
11756412
11923280
16697215
20452955
27603133
20398329
18372248
15001356
15808505
10217147
19440234
20138985
12431783
10753973
17855660
19216069
28358423
20214616
11463845
9829964
17570479
17646672
16680151
11231573
15169778
12851486
31575057
25241761
23109003
21933447
10949026
16775416
23886938
26436589
16288292
11715018
16055744
18636226
15023346
9812896
12042314
17680028
24848107
16982699
11779850
10722653
20832730
18570873
20307683
34069970
17052453
15798220
|
CDKN1A
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
21988832
23443559
26186194
25241761
27107012
8756624
25416956
16328436
31515488
16189514
15232106
32296183
23880157
26496610
9716181
|
CDKN1A
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
23443559
26186194
21308745
9660939
8756624
15890360
9380407
8242751
8662825
12947099
9632134
17679094
26496610
|
CDKN1A
|
CDK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
23443559
15169570
18850315
9658399
16962592
15232106
9632134
16189514
8622677
15695403
20102411
8242751
9464540
23007395
7626805
9106657
12383116
30193583
17556661
23543736
8756624
|
HES1
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
22311706
19541765
15870295
19598246
19609448
|
TP53
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15145945
15988033
19235838
10516009
21478095
14984207
19427386
|
AKT2
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12244303
18593906
|
TP53
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21340684
20066118
20457558
20182602
6396087
|
LYN
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17145710
17254966
21423214
17254967
20966355
33147476
|
AKT1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
69.0
|
1.0
|
Omnipath
|
22119715
11756412
16780593
11923280
16697215
16209941
12244303
20398329
18372248
14967450
18710949
15808505
26053093
20138985
14504289
20214616
12244302
17570479
18593906
23576547
23400686
12851486
15169778
24651496
19829074
25241761
10949026
16288292
11715018
18636226
19377290
9812896
12042314
17680028
10722653
20832730
18570873
12244301
17052453
|
CDKN1B
|
CDK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
35.0
|
1.0
|
Omnipath
|
23602568
8978686
23707388
21439954
18850315
16326706
9658399
14597415
18615582
10198259
16782892
9632134
16189514
17053782
11360184
9311993
17092340
20837141
26186194
25241761
15695403
9464540
19470470
9106657
10908655
23543736
11940657
18285702
|
CDKN1B
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
17145710
8684460
26186194
9660939
17254966
15890360
16209941
12947099
12501191
26496610
9724724
9311993
9716181
|
CDKN1B
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
14597415
16189514
10342870
16328436
|
HRAS
|
CDKN2A
|
â—¼ UP_REGULATES
|
✅
|
+
|
15.0
|
1.0
|
ACSN
|
10358164
12134164
12447393
14764585
16102570
17673906
20841469
24027568
24954210
7510700
7673236
8551221
9069260
9763606
9846483
|
TP53
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
16103197
22467867
18555006
8631601
11402335
19649205
22020338
21164364
17265068
16764954
15775976
22056554
18275833
21483786
10348346
19216023
12384561
12091906
19901969
11360201
15205322
11818069
21892281
10980602
11739748
11559812
24672805
10097151
17907153
19244234
15361884
10652576
9436028
21447739
20569441
21555589
21637567
10816133
9774662
19240179
|
DMTF1
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21892281
10097151
22039255
21062982
15601844
17546045
|
ETS1
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17370299
22714536
11234019
19240179
|
CDKN2A
|
CDK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
37.0
|
1.0
|
Omnipath
|
17145710
11900540
23602568
9529249
11556834
16161044
17881001
17517622
15065884
9228064
15232106
26496610
10585280
17909018
26186194
17353931
10580009
17955473
10491434
12529334
10719365
28042499
8259215
24855949
8891723
23455922
|
CDKN2A
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15856024
15989956
9724636
19960022
12740913
17158541
12640129
19590512
|
HMOX1
|
NOS2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
10.0
|
1.0
|
ACSN
|
11399519
11875494
15644117
16127449
17260466
17689680
22461508
23390297
6357187
8871614
|
HMOX1
|
MMP9
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
10.0
|
1.0
|
ACSN
|
11399519
11875494
15644117
16127449
17260466
17689680
22461508
23390297
6357187
8871614
|
ETS1
|
HMOX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15590657
20348279
16310515
10022513
|
JUN
|
HMOX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8774698
24755082
8872603
20486760
20833713
18689604
|
AKT1
|
HMOX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15581622
|
EPO
|
LYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
9334184
9974393
9774108
9573010
11231127
2163696
|
LYN
|
FCER1G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
12524384
19909365
21910624
24445665
26552706
8064233
8132624
8478617
8892616
|
LYN
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
12524384
19909365
21910624
24445665
26552706
8064233
8132624
8478617
8892616
|
LYN
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
9820500
24129562
10022120
18818202
21469132
24607955
18083107
17389395
19285079
11536198
10592173
25045209
7797565
11380624
9857068
7513017
30923129
8621719
10477689
7831290
15701717
27258042
19369195
28082678
8666899
9535867
8657103
14871838
|
LYN
|
MS4A2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7528770
7612892
19356729
22845063
|
LYN
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
18083107
8629002
12573241
11598012
19369195
10051622
9012831
8630736
9730885
10811866
9052864
8058772
11226282
|
MAPK12
|
MEF2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
10805738
9988769
9069290
9858528
10330143
|
MAPK12
|
ELK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15187187
19436832
15140942
20506250
21614932
16393692
11274345
|
MAPK12
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15187187
19436832
15140942
20506250
21614932
16393692
24818748
11274345
|
MAPK15
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
26035356
12169099
20395206
|
PLK3
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
15489221
24395704
11709713
10801407
15254178
16581545
12242661
16713569
12111733
11551930
19607708
10673501
11875057
11447225
12548019
|
PLK3
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17804415
21296815
19690332
19413330
18650425
18669648
15302935
|
PLK3
|
PTEN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
24830552
12297295
20940307
23210979
|
PRKDC
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
79.0
|
1.0
|
Omnipath
|
15355354
19398950
15254178
9372954
11483158
7862459
16713569
11875057
11551930
11883897
12548019
25168287
8502477
11709713
10446957
28145533
22726545
24886358
16552184
12242661
17570479
10196661
10747897
9885574
10673501
12091386
22355272
9765199
15489221
9561848
10801407
22504299
22444248
15177184
11042698
10358069
10470151
10606744
9744860
16397295
12959929
12064478
27130668
10951572
12111733
25937999
15381073
28102346
9363941
19918261
|
PRKDC
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
318.0
|
1.0
|
Omnipath
|
27120806
14555685
20028775
20176926
11287317
27542271
26740621
11731414
12393602
34197700
17993646
21940452
21946537
11278872
22975685
16908595
18316359
34073781
24735537
18039660
24652283
20856200
26170313
21300025
15388791
19144640
26297026
17545609
33941854
16280327
10625301
33845796
25918246
34385295
17537996
14645219
20804212
15084259
12169689
21795477
22071574
23913047
34021259
21695150
15684384
33958720
14530366
16670089
19487463
19223464
17303569
25481872
15475446
17116771
28967905
33753495
12438236
29562639
16753042
33836561
19073147
15169778
16891474
19477925
16338973
16397245
34562454
15821749
33767437
34087103
11409731
18381446
15737995
27481935
11313365
26700621
17210635
25447541
33931486
17827393
17126298
15262962
28542588
33574930
11821945
20471940
15461589
17077177
33579227
26921343
17386266
33744230
26848618
12944390
33566837
26902421
21042280
21763421
34380642
18321849
14593122
25775124
25739674
17229808
26351843
24102046
23757022
33532186
16043647
24632620
12781924
25738875
10864894
17974989
25719244
15806160
16497987
25851605
20501647
18439899
28209968
10973320
24819169
25745998
34383763
19592491
19244117
19204084
29088759
26871475
34257082
26755732
17237292
17709744
17640984
34405859
18480058
33995548
22310280
20211239
12052823
22580611
31937616
19920202
26745759
15905173
12499277
15028555
27162341
21106850
33562475
30065170
23462102
15678105
15642728
27065332
28558072
28977846
15319269
21339742
15855334
21045808
20145118
21297104
18632646
17379600
15471950
23474758
26887938
11375271
20013032
18701889
16540596
15314172
28515473
15964826
19638206
25892239
28692056
20530876
27505672
25100728
21242970
17297446
10542266
14670178
15548374
33741342
12429574
11002428
15831486
17116756
25435370
32833881
11402048
25361894
15207915
20729916
15625077
18677106
12869565
11250155
21356307
15967841
31936857
25943101
18394555
12644590
14500543
18691549
27197158
15623569
33477794
12062056
16754797
15383526
21909137
21949775
20085797
16807298
15899889
33868961
23940660
23434580
33927349
23899556
14990993
12000752
27880719
26065416
19060924
34520759
14679308
15334055
17283158
25257795
17548608
30586628
24437487
20124472
15289327
23325788
21208159
33664452
31679687
12791703
15047712
17166829
26146988
17329400
20660158
21532621
21806543
20179209
25661488
20957047
17562705
19915805
12606948
17277771
10377409
25893295
17270736
16407838
20597130
15047168
28658616
16357520
15537647
12818176
11425855
17210830
19800394
12506011
21310961
16963136
21996732
15695828
33835469
11701613
19010331
26686089
28915558
15467762
17586693
18456663
34381564
18765673
20233713
34208786
11029403
22084251
20622007
12077256
11313948
16917505
19448664
27391337
15792956
21172654
15608670
12438239
19875458
22014578
25071014
11809760
18728186
31391321
33891611
19805619
33407730
25868858
25320242
34348155
20832730
|
TP53
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
15656906
12807729
15067344
15734740
11064449
15262117
16234237
10778946
15371422
22496369
18754863
19649288
19787269
|
AKT1
|
TERT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
25999477
22366458
10224060
17570479
22902867
15843522
18775701
|
YY1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10787423
10634504
8816507
10505791
18391986
|
JUN
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
22859294
17321721
20697347
10348347
12963547
10072388
22353755
18604200
|
ETS1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12145208
19022222
8649821
10510472
|
TP53
|
LIF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15193492
18431400
18046411
22032922
19907922
|
TP53
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
8108142
20639906
9377555
21325822
16684540
9833779
10910082
16835303
23449391
8521408
15860260
11971180
11559575
|
TP53
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17311279
15899818
17077165
18635530
|
TP53
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17202838
18084622
18945670
11504717
|
TP53
|
CCNA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
16931621
8270002
9275177
19671680
16571800
8641461
9360984
21952947
|
TP53
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18980971
22451655
23048035
10029407
9343394
19853299
11792711
19939245
17088079
17258390
|
TP53
|
CCND3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17530187
19861536
|
TP53
|
HRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21552926
9662334
11127813
21552928
|
TP53
|
DUSP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8702807
20196119
15611668
18403641
23149933
12890671
|
TP53
|
NOS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11131279
11092782
9194524
8637893
|
TP53
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12732139
10618379
22264233
23706820
14514686
8183578
14761612
16138117
18593586
23063463
8119773
|
TP53
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12485897
18661553
19763735
|
TP53
|
FASLG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17196791
9889415
20393600
9841917
|
TP53
|
KLK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15540784
11791186
11504717
|
TP53
|
AFP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
11572852
14522900
11798803
11891535
18212064
15743813
16203738
18573881
15657445
9891062
|
TP53
|
ACHE
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
20935676
9649502
10514438
17209038
9288775
22243239
9525640
2936901
7823921
10435630
|
TP53
|
SIAH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
20181957
20421190
14985507
11852084
|
TP53
|
PTEN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
22957312
15843377
12917634
21637289
17344317
12839924
11545734
18172008
19173293
20554748
19079342
14984207
|
CSNK2A1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
53.0
|
1.0
|
Omnipath
|
23443559
15358769
9315650
19413330
11285227
11551930
11883897
22975381
11709713
16083285
1088347
33745968
16552184
10884347
10747897
10673501
7936649
12628923
25241761
21127074
16964247
24725084
10606744
10348343
10951572
|
DYRK2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
111.0
|
1.0
|
Omnipath
|
29296831
21383696
14749479
11740489
20171273
25778922
15843377
33906076
10581258
15750624
15897882
15706352
26236013
24899407
33572115
17906639
20935676
24379358
17386256
15870257
26346493
12427754
34103685
17567906
11101524
17210684
18536714
15381073
19965871
26578795
26087959
28060750
21765464
20673369
34216619
16601678
17380123
33443163
18216278
21642861
15526030
22878263
17349959
16738336
20696760
19882354
16219768
17105820
16793543
17332358
24901999
16247456
24196445
26804244
15657359
27208501
18056705
21765463
23420876
22797063
16377624
19861417
18160537
12676607
20123963
15489221
17591690
20514025
23149944
19857493
17891183
27034505
11780126
21057547
25944899
26341817
17349958
20962272
22525275
19828042
12902982
19465479
15471885
15322239
11495913
12907596
32083004
25915850
20018442
24145406
26029824
21394211
12093737
33872315
20610713
20024960
26113041
20811699
18560558
21660965
16717128
11030628
17107963
|
MAPK9
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
79.0
|
1.0
|
Omnipath
|
12356735
14665630
26158765
18778462
12969974
12861053
15254178
17135248
18669630
12384533
17363488
17698850
11283254
10706102
21454683
18931691
11551930
11397945
14612532
15064747
15963507
11175334
11423984
27147566
29234486
24657168
10581258
14517211
17353187
10673500
22030623
14527925
22728651
17525747
15629715
9393873
11447225
15671037
22285752
17245430
15140942
28673515
23871434
11078726
20041275
11896587
16731759
17121812
33514736
11861384
25431954
12810724
17967874
12955074
21832239
16818520
12756247
23798621
11526498
20009884
16713569
10202145
11850826
11896572
10710310
10570149
12959929
15269203
11583595
21148320
|
MAPK13
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
15187187
19436832
15140942
10581258
20506250
21614932
16393692
24818748
11274345
|
CCNA2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14640983
10884347
16713569
|
TP53
|
PTEN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
21336307
18431400
18339852
12620407
17409411
18172008
17823410
16713569
21518799
21483453
|
TP53
|
SIAH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12077306
12438652
14985507
15326481
|
YBX1
|
MMP13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
11641401
10330183
11274169
17822788
|
AKT1
|
YBX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
17081983
32028981
33911076
26318844
33151228
20844753
27591085
17704806
21423216
19036157
31906126
15806160
24335958
34272387
33379356
19651622
31387591
16354698
19664994
|
YY1
|
IFNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
12584314
16954376
18225953
22287632
22065573
16260628
|
YY1
|
IL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10518827
16922677
10359895
17270283
|
CSNK2A1
|
YY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22184066
23226345
|
YY1
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
16713569
12913000
|
SMAD7
|
COL1A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
14520013
11279127
9886263
19641518
19397700
16126788
|
DYRK2
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
20831597
22307329
|
CD247
|
FCER1G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
39.0
|
1.0
|
ACSN
|
10358164
10562324
10925299
11353765
11385609
11438547
11449354
11489965
11513144
11875494
11994457
12055234
12393695
12731048
12811837
15081523
15099567
15778339
16287995
16713974
17100877
18768831
20435894
20814939
21059766
2139103
22267813
23414611
23508573
24378531
24445665
7523143
8344348
8478617
8551221
9603467
9625766
9738502
9751747
|
CD247
|
FCER1G
|
â—¼ SHARES_COMPLEX
|
|
|
39.0
|
1.0
|
ACSN
|
10358164
10562324
10925299
11353765
11385609
11438547
11449354
11489965
11513144
11875494
11994457
12055234
12393695
12731048
12811837
15081523
15099567
15778339
16287995
16713974
17100877
18768831
20435894
20814939
21059766
2139103
22267813
23414611
23508573
24378531
24445665
7523143
8344348
8478617
8551221
9603467
9625766
9738502
9751747
|
FCER1G
|
IL6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
12731048
15081523
15099567
20814939
23414611
2451784
7590867
9625766
9952373
|
FCER1G
|
IFNG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10925299
11438547
11489965
11513144
11875494
11994457
12055234
12811837
15081523
15778339
16287995
16713974
17100877
20435894
23414611
23508573
24378531
9625766
9751747
|
FCER1G
|
SYK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
12731048
15081523
15099567
20814939
23414611
2451784
7590867
9625766
9952373
|
CD247
|
FCER1G
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
39.0
|
1.0
|
ACSN
|
10358164
10562324
10925299
11353765
11385609
11438547
11449354
11489965
11513144
11875494
11994457
12055234
12393695
12731048
12811837
15081523
15099567
15778339
16287995
16713974
17100877
18768831
20435894
20814939
21059766
2139103
22267813
23414611
23508573
24378531
24445665
7523143
8344348
8478617
8551221
9603467
9625766
9738502
9751747
|
SPI1
|
FCER1G
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18629488
21057087
23534406
24639354
|
FCER1G
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9280292
17145710
8071371
8810294
8663460
|
PPARG
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
16155367
17255125
20663893
15659119
15531761
20473515
18226310
18060855
12110006
20508203
11606585
10930382
16105976
|
JUN
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
19162185
18024959
18443042
14752027
22674286
23583295
19299558
12667961
10918580
19371341
26554515
|
CCL2
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10477718
16298345
1629834510477710
|
IFNG
|
IL10
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
IL10
|
DUSP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10433356
10542212
10623821
10925299
11207245
11438547
11875494
12193690
12811837
12818165
14607900
15282297
15579430
15749903
15833879
16200688
16424049
16713974
17404308
17485448
20184663
20435894
20547845
21115385
21191065
21220452
23124025
23508573
24378531
26755705
9834059
|
SPI1
|
IL10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
20072143
19592658
18843277
12424622
25567680
|
CCL3
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
11170631
16298345
10477718
23765404
15075201
9468473
20219869
9169459
11700073
10699158
9334377
9790730
22633458
12964882
|
CCL4
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
10498628
16298345
8663314
10477718
9468473
20219869
23597562
10699158
9334377
9790730
16467191
22633458
12427015
12964882
|
NR5A1
|
STAR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
20924043
22155568
11250933
11427738
19237537
18987158
10319323
18596066
10403575
10852468
23530236
17065415
19455657
9013761
16439455
9801462
9832418
18165439
22427816
23313103
10960482
21632081
17082260
10919277
10499490
20650879
21913902
11111087
19022561
11459805
9029708
15129808
|
AR
|
NR5A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
11518799
|
SYK
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21674813
21459462
19014652
12711606
24101387
|
BTK
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12909638
30887112
12167702
|
CSNK2A1
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
32.0
|
1.0
|
Omnipath
|
10783893
16007147
9721103
11673497
12138192
10723127
7796813
8657113
8622692
10421793
12167702
12403772
8668171
8657102
10398585
8601309
9214631
|
VEGFA
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
VEGFA
|
VEGFB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
58.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15308668
15501236
15520864
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16887996
17086423
17496910
17673906
17883421
18835194
19414323
19449109
19454690
21372296
21378271
22064427
22461508
22464172
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
VEGFA
|
VEGFB
|
â—¼ PROTEIN_INTERACTION
|
|
|
58.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15308668
15501236
15520864
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16887996
17086423
17496910
17673906
17883421
18835194
19414323
19449109
19454690
21372296
21378271
22064427
22461508
22464172
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
VEGFA
|
SYK
|
â—¼ SHARES_COMPLEX
|
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
VEGFA
|
SYK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
VEGFA
|
ETS1
|
â—¼ UP_REGULATES
|
✅
|
+
|
31.0
|
1.0
|
ACSN
|
10022831
11166270
11708773
11960372
12490555
12629515
13678960
15099563
15111329
15181457
15501236
15520864
15573129
16002046
16572188
16716598
17086423
17615296
19414323
21041997
21372296
22064427
22349261
22461508
23390297
24346288
26201938
8837607
9157999
9570538
9753319
|
TFAP2A
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11191053
16790435
11731421
9049304
12570801
14744778
8466753
11007955
23506169
|
JUN
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
9256279
11204570
11353786
23274526
11678207
17341624
20015448
8910439
16328781
11731421
15039660
19553068
20432243
7887961
12163680
10885623
11281649
14602779
18294451
15277220
|
AR
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16007189
23369005
18768969
18612129
15003169
|
ARNT
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
15930297
18372249
17413038
21814878
7641334
22306343
19020709
23086815
16774940
8756616
10702253
22076197
|
ARNT
|
VEGFA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
7539918
17987801
1823643
16716598
12829734
9159130
13130303
9746763
12080085
11566883
10403805
7768934
8943284
15451019
11528470
9278421
16887934
|
PGF
|
VEGFA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12796773
25241761
12086892
8621715
|
VEGFB
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
VEGFB
|
SYK
|
â—¼ SHARES_COMPLEX
|
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
VEGFB
|
SYK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
CD3G
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
8226994
18818202
8862523
8340414
7522622
7530449
9314552
|
CD247
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
8226994
18818202
8862523
8340414
7522622
7530449
9314552
|
CD247
|
SYK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10358164
10562324
11353765
11449354
12393695
12731048
15081523
15099567
18768831
20814939
21059766
2139103
23414611
24445665
7523143
8344348
8478617
8551221
9603467
9625766
9738502
|
SYK
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
18083107
8629002
28368423
11598012
28359287
29455639
19369195
10051622
9012831
8630736
28088788
11226282
|
CD40LG
|
IL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11581322
15034038
17200410
17371980
23125331
8760829
|
CD247
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD247
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
16188976
16282498
10607567
16979207
11160719
10618429
11070003
|
B2M
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
10358761
10559964
11154916
11509172
11717192
14508489
16181333
22076556
22790179
24457417
8642276
|
CD247
|
IL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
10562324
11062502
11353765
11385609
12731048
15536084
20814939
21059766
23414611
8478617
9625766
9738502
|
PLAU
|
PLAUR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11306493
18633355
19833085
21840487
22470492
22595692
27216177
7512720
7521688
|
PLAU
|
PLAUR
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11306493
18633355
19833085
21840487
22470492
22595692
27216177
7512720
7521688
|
FGF2
|
PLAU
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11874475
18232728
18633355
18776941
19508171
19631971
21098712
22652804
23123598
25374926
9242465
|
ETS1
|
PLAU
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
16127276
15247905
11556732
20645833
9185999
10211993
8683934
18772901
|
PLAU
|
PLAUR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
3031025
16879932
3023326
11501527
18376415
16189514
19017363
16456079
|
TGFB1
|
SMAD7
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
11133108
11708773
12490555
14557817
15111329
15181457
15252039
15548370
16474430
16607286
16716598
17615296
17934056
18403754
19010789
19109155
19920116
20519943
20644162
21041997
21278795
21900405
21909923
22703233
7594497
9157999
9335507
|
SMAD7
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10887185
15855807
9886263
20631490
22656308
19214138
23633623
14600158
10753944
11912247
11385614
11180003
17928287
19010789
22496417
22841502
17074765
15496141
11448947
|
TGFB1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
19010789
14718519
16474430
17934056
20519943
9335507
21900405
11133108
14557817
15548370
19920116
|
IFNG
|
TLR4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11672593
11777960
11870632
11964313
12032143
12413632
12811837
12818165
14607900
15634932
15644117
15778339
15811952
15814715
16286920
16306937
16424049
16713974
16917499
17016554
17114424
17559085
1825141
18272812
19833085
20038811
20154735
20547845
20819927
21149606
21411734
23508573
24658051
26755705
2965306
6425450
9834059
9864217
|
IFNG
|
IL18R1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
IL4
|
IFNG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
17.0
|
1.0
|
ACSN
|
10485906
10820262
11160275
11371360
11870632
12401408
12433365
12496409
12818165
18250477
1825141
20184663
20856220
21097505
23124025
2965306
9834059
|
JUN
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
20006311
22123848
14734615
15187132
11943142
20304822
17556653
1314139
17105733
22413812
19265145
11801649
16713974
7759501
12836278
15522880
12626576
9558063
8756632
18641343
22351517
|
SPI1
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15345588
19502584
12130529
7814871
9545284
20585034
|
AKT1
|
MMP9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
17409395
17680028
18471976
19440036
19930715
19945467
20214616
20398329
20609352
21084277
22131018
23572150
23589069
24030100
25136802
26597054
27328425
27510662
27572739
29556339
|
ETS1
|
MMP9
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
10048576
15001984
15003528
15111329
15181457
16079281
16391805
16556862
16682805
17615296
17872466
18337545
19208835
19564415
20589835
21041997
21081489
21317430
22439866
22608498
23691193
24376839
7512751
7528107
8844971
9157999
9811054
|
FOSL1
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16554298
22514284
22514348
15319566
17572495
|
JUN
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
16798740
16554298
11774399
15949416
11429784
15777790
16014933
10935492
11326313
18809380
21474819
21963718
19455716
9136992
17572495
23176293
15708369
|
ETS1
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22270366
15949416
16722933
11556732
22206665
10949659
|
PPARG
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
20021931
22472882
22207709
9665460
|
ETS1
|
MMP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10048576
16391805
17615296
15111329
19564415
9157999
16079281
21081489
21041997
15181457
|
LEF1
|
MMP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17306568
17666529
23343194
21285352
15576399
21151179
22761862
22290435
16039586
19619488
19623618
17143292
|
MMP9
|
TGFB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10652271
21900405
25241761
|
JUN
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11413310
10760799
19828633
10075858
20862675
26096887
7513046
|
CCL5
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
16298345
10488147
28381538
10699158
22633458
9289016
12213786
8663314
11449371
10318947
12964882
25923671
9207005
23480650
11116158
10477718
14637022
9334377
9790730
|
SPI1
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15013752
23509362
18680724
19502584
25567680
|
CEBPA
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15158360
10748205
11975924
|
AR
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12237244
8824277
19074897
11049111
17374439
11410519
20610535
19363165
|
JUN
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
26513016
10542237
21069809
15389813
15158360
20225236
12667961
20371366
20511231
20862675
8453101
10202034
18502099
10037779
8830832
19687301
21098092
25567680
20351184
17341596
11120852
21312239
24676671
|
PTEN
|
AKT1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
22.0
|
1.0
|
ACSN
|
10753747
11747822
12040186
15721744
16288286
16982858
17218262
17409395
19440036
19847259
19945467
20609352
21084277
22179046
22465479
23732914
24030100
24254977
25364523
26597054
27328425
27572739
|
PPARG
|
PTEN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18065496
16775433
16425225
23867870
20198337
11378386
|
AKT1
|
PTEN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
19903340
15987703
10790335
20596030
10592173
20605778
10866658
12077256
11035045
16107342
12297295
|
CSNK2A1
|
PTEN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
34.0
|
1.0
|
Omnipath
|
16107342
33760042
18723495
25823029
21840932
10866658
24766807
16690621
21779440
24706748
19662498
28263967
15987703
11035045
12077256
24047694
11707428
22413754
17444818
26832662
12297295
|
PTEN
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
15205473
24480624
|
TGFB1
|
ETS1
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
11133108
11708773
12490555
14557817
15111329
15181457
15252039
15548370
16474430
16607286
16716598
17615296
17934056
18403754
19010789
19109155
19920116
20519943
20644162
21041997
21278795
21900405
21909923
22703233
7594497
9157999
9335507
|
PPARG
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
14702344
17625041
31023188
17995524
16321227
18615188
14693716
12711314
16611854
18991162
|
JUN
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
8058069
16327802
16730810
23437118
8183578
16365456
22429882
23936544
15546613
10843986
16978906
23762330
7521696
8631909
12794825
|
MMP2
|
TGFB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10652271
25241761
16189514
21900405
|
NOTCH1
|
HEY1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11486044
11486045
10964718
12814948
14739937
20007915
11971902
21956839
|
NOTCH1
|
HES1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
10520600
11120788
10066785
16869730
12814948
7566092
21956839
9819428
10933396
11866432
20007915
10205173
11741889
19165418
15546612
|
NOTCH1
|
LEF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
11604490
16713569
18988627
|
NOTCH1
|
HES1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23343194
19000719
18495817
16039586
19619488
17143292
|
CEBPA
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22685373
25119735
8999951
18199703
|
PPARG
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19395102
18485432
20107546
20554962
16303327
20889551
15331599
12695526
15720834
|
JUN
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
18684922
16701870
24048734
14686613
24284797
15057743
12643600
17197543
11864912
10817569
12218154
22031759
17586662
10969814
19064995
12716652
27856305
25582859
17471497
22095787
16818736
23176534
14670967
18435575
16846747
19734226
16299055
14612204
18772138
19132242
12209633
15939312
16834785
11399048
11120852
25567680
|
MEF2D
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9252389
7760790
12054430
|
MEF2A
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
12574153
10330170
20590529
9252389
8355696
12016267
19389706
7760790
1406636
10403485
12054430
|
JUN
|
IL12B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15187114
15270850
14688340
25567680
11279072
|
JUN
|
IVL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15586248
22649503
16374477
15790882
9424084
9506439
17882273
15025563
7759510
20006635
17205062
21966511
15037572
|
JUN
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
9190901
12760745
19890352
1900839
8135780
11509589
8524292
7579683
10330159
9862439
15840658
|
JUN
|
IL1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
11306276
18566416
7935377
10226077
14686613
16365456
11145674
17283046
20463008
23608488
8133045
8798756
18789903
16729332
|
JUN
|
GCLC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10751553
11007940
11233143
11912197
9610371
9613591
10350652
16054171
10218647
|
JUN
|
IL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11579103
12452838
10491186
17845581
9234684
7615560
8120390
17687519
7592673
16373364
|
JUN
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11382920
17933457
20371606
16453281
18556800
17919072
|
JUN
|
GJA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8606973
16978907
12064606
15618352
10421804
|
JUN
|
EDN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16740983
1918021
22301113
21239258
12208352
21216243
|
JUN
|
DCN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
7499226
8798756
8940199
|
JUN
|
MMP13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
9119388
19783677
21461405
11641401
10779518
17905570
14686613
19038372
17626252
10911363
8957070
15994313
9989817
9334186
9212062
12032154
9138284
17822788
14575638
15084595
22158614
11691923
16023836
11852231
12460732
15063796
19126648
11274169
20067416
22128168
11689447
16919424
20338993
10891395
10830307
|
JUN
|
CCNA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9486962
23385061
15574764
17182846
15737994
21069729
9511728
20531301
21029732
|
JUN
|
PENK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
7477937
2512642
1491720
7935470
8931456
9147818
8632147
|
JUN
|
CYP2J2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12737630
20194533
20180943
16008525
|
JUN
|
PLAUR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
11234878
15040011
8761947
16893520
15963460
8798512
20736951
10471035
17510314
|
JUN
|
MYB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
1527086
8670250
12475180
|
JUN
|
IL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8996240
10772943
9889198
9133600
21989417
9310836
15546613
21454593
12594266
|
JUN
|
FGF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9456251
10913304
10559225
11281649
11551904
23485603
23331079
|
JUN
|
MMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
22437631
10913304
20463008
20225236
10206959
16707434
20648623
9178763
15027120
19708869
10914841
15090544
14550555
9923649
11156425
9334186
8798622
16317516
19028685
11259586
16380175
12871225
15467742
10995748
21640141
16569638
|
JUN
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
20557936
12370343
10700231
12884855
8436291
9541574
8397339
1737937
9605137
8683110
21832163
9590239
7989759
9774418
16116194
8473495
8114694
10878360
10320367
9233628
7642615
17097050
7565732
8468462
8660843
7739550
8051409
1740667
19181930
|
JUN
|
BTK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8683110
7915738
8468470
14764703
16365438
|
JUN
|
FASLG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
18196534
9873041
9660938
14563113
9710625
11003676
19670268
10811113
9468493
15160330
15546613
12618758
11397794
10744679
|
JUN
|
SPI1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17283046
10411939
9178763
9988737
|
JUN
|
FOSL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18435914
15806162
13679379
17082637
|
JUN
|
IFNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9660935
18035482
22065573
10848607
20048166
22083261
17376932
|
JUN
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
19268464
15212943
14767528
19940138
11414701
15777790
20353950
17116726
16000878
|
JUN
|
NOS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17105733
17940019
16421203
18596035
11254551
14962367
14686613
16771680
9776360
12788789
12020969
|
MAPK9
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
73.0
|
1.0
|
Omnipath
|
17143273
17145710
17637567
12584171
20506250
11948398
15378002
16824735
9687508
8654373
20028971
12788955
9305638
15302935
26091349
33822843
18362184
17875713
16393692
9405416
17570479
1922387
18252863
25561726
7737130
10490605
17189706
11896587
34408980
11274345
20178741
8525045
16076903
7992057
19527717
7600582
17215518
8985011
11801649
19118012
11278395
8001819
8137421
19436832
16533805
8945519
12881422
9315636
10385525
12093796
14523011
19910486
15212693
8157646
12040039
11562357
|
AR
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
11577103
11518798
9211894
8798722
16713569
9591784
17721441
|
CSNK2A1
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
25609649
1846781
11948398
15378002
12531896
19413330
8654373
15302935
11075956
12628923
11896587
1516134
8464713
11971971
1651323
8137421
9685505
91332050
|
UBE2I
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11877416
16713569
16055711
10788439
8733011
|
PAK2
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21177766
|
GSK3A
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
1846781
24214991
91332050
1516134
1956339
16023596
92065884
1651323
|
JUN
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8557686
20195357
|
JUN
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
18813803
19219074
16406505
16880536
16054035
19190345
17000779
17439715
8545107
16396903
11274345
20107231
|
JUN
|
FOSL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9160889
11708771
23661758
20511396
11431474
24029232
11912197
|
JUN
|
SPI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12393465
10411939
12091339
|
FOSL1
|
GCLC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11912197
15988009
16054171
|
ETS1
|
FASLG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20617570
11970950
|
PPARG
|
NOS2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
11.0
|
1.0
|
ACSN
|
11399519
11875494
15644117
16127449
17260466
17681149
17689680
21234400
23390297
6357187
8871614
|
CEBPA
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
22553076
20725087
15664998
15110775
18619497
19059241
9367890
15158467
23071089
10862621
15632071
16580992
|
PPARG
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15590897
19666848
19732722
16020752
|
PPARG
|
MMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
19046432
19296842
11869069
15090544
|
PPARG
|
NOS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15950726
11595817
19997048
10848596
|
PPARG
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
19217272
16611855
10671476
15187132
11726648
19712756
|
PPARG
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17908458
17625041
16609149
15838654
19345798
17425848
|
PPARG
|
MMP13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19046432
22472882
11263774
19296842
|
PPARG
|
LPL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17658475
10098492
8895578
18948972
|
PPARG
|
FABP4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17322100
9831621
8943212
23805908
10935488
11574398
10425206
21047783
20656057
16854242
20160124
|
PPARG
|
NR1H3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11604492
16959872
24751522
14703507
|
UBE2I
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19692572
15507114
26192107
|
TLR4
|
BTK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
21873236
11544529
22454496
16439361
15944945
12724322
17726518
|
SPI1
|
TLR4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10734131
11672593
11964313
12032143
12803886
12811837
16283355
16418395
20510871
|
SPI1
|
TLR4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16424218
10734131
17495427
24155397
20956019
18485892
16093364
16785240
11780066
|
SPI1
|
GATA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
10734131
10753833
12803886
16283355
16418395
20510871
|
SPI1
|
GATA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
10734131
10753833
12803886
16283355
16418395
20510871
|
CEBPA
|
SPI1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17671233
24429361
14636649
20972335
12949251
14592841
12032776
|
SPI1
|
GATA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
14559995
10411939
11023493
11001896
20304827
|
SPI1
|
BTK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8934542
8562928
10362515
|
SPI1
|
IL12B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11449355
25567680
11254706
|
SPI1
|
IL1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
10801783
11359842
7799967
18173740
18566416
9376596
11823535
19423615
10328874
17283046
10453013
16439360
17386941
7609733
12061786
9360994
10490619
|
SPI1
|
TIMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8559663
15485866
15102003
10497161
10388555
22472882
|
GATA1
|
SPI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
10411939
10753833
15676205
10364157
12202480
|
CEBPA
|
SPI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10397723
12091339
|
IL2
|
IL2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL2
|
IL2RA
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
ETS1
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7876544
9780181
24019486
|
IL2
|
IL2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
6815536
3095922
15265897
12649439
16477002
15933202
1940342
17032757
15178252
8260650
3116143
8894436
1993646
8580082
8960125
|
IL4
|
IL5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
10485906
10820262
11160275
11371360
11870632
12401408
12433365
12496409
12818165
18250477
1825141
20184663
20856220
21097505
23124025
2965306
9834059
|
IL4
|
IL13
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
10485906
10820262
11160275
11371360
11870632
12401408
12433365
12496409
12818165
18250477
1825141
20184663
20856220
21097505
23124025
2965306
9834059
|
IL4
|
IL23A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL13
|
IL23A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
32.0
|
1.0
|
ACSN
|
10485906
11867689
12223527
12401408
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
7512720
7521688
7543512
9535722
|
ETS1
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9190901
7478534
8611694
15907486
12475968
15123671
|
ETS1
|
IL3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
8704203
12387738
25861992
|
CD3D
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3E
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3G
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
ILK
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
11546794
14500673
12176337
11445557
15899889
23840605
9736715
12149249
10592173
11313365
16189514
19460343
11278835
15212693
18772455
10226025
11825911
|
FGF1
|
ETS1
|
â—¼ UP_REGULATES
|
✅
|
+
|
6.0
|
1.0
|
ACSN
|
14517404
16272825
16682805
21081489
26183471
9242465
|
ETS1
|
MMP1
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
10048576
15001984
15003528
15111329
15181457
16079281
16391805
16556862
16682805
17615296
17872466
18337545
19208835
19564415
20589835
21041997
21081489
21317430
22439866
22608498
23691193
24376839
7512751
7528107
8844971
9157999
9811054
|
ETS1
|
IL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17845581
25861992
10212281
16373364
|
ETS1
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12039986
16391805
12122099
17088079
|
ETS1
|
ANGPT2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18720385
15003510
17287278
|
ETS1
|
MMP13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16127276
22270366
9138284
18639639
8683934
11852231
|
ETS1
|
MMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23060436
21244711
20826544
15247905
11829472
17283078
16278291
11556732
17214640
15972796
16317516
10949659
11830328
9178763
16569638
|
ARNT
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
17615296
9157999
9278421
11708773
16716598
12080085
10403805
16887934
15181457
7539918
12490555
1823643
12829734
13130303
15451019
9746763
8943284
15111329
9159130
11566883
21041997
|
ETS1
|
MMP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10048576
16391805
17615296
15111329
9157999
19208835
21081489
21041997
15181457
|
FOSL1
|
PLAUR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11234878
16893520
8798512
10471035
17510314
|
TFAP2A
|
PLAUR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9988707
17317820
12817472
|
FGF2
|
SDC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
20382221
8621465
16982797
1101561416982790
8609172
11015614
|
AKT1
|
MMP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
17409395
17680028
18471976
19440036
19930715
19945467
20214616
20398329
20609352
21084277
22131018
23572150
23589069
24030100
25136802
26597054
27328425
27510662
27572739
29556339
|
AR
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20589722
11278645
17896924
18687691
22740037
12621049
12063252
22970326
|
MEF2A
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10973962
12138087
15931671
21689744
|
CSNK2A1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
29732088
17374729
21506126
11689703
10671551
12149249
15818404
10747897
10837139
20976471
19662498
21285348
11035045
11707428
21735093
17444818
20558317
11972058
16707567
|
AKT1
|
GATA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
27053161
16107690
20101202
8206977
26680303
|
AKT1
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
70.0
|
1.0
|
Omnipath
|
12759249
20166139
11756412
10376603
11923280
12446767
16697215
11044445
20398329
18372248
11696579
16126727
16839566
15808505
20138985
20299462
10908731
20363286
11988487
11425855
20214616
23103584
11729179
16043647
17570479
12171920
25460366
27322328
11978735
15169778
11029403
25241761
19654415
10949026
18048761
11715018
12791703
24379783
18636226
9812896
23397142
17680028
10376602
12431978
10722653
20832730
18570873
25009123
17052453
|
AKT1
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11546794
14500673
12176337
11445557
9736715
12149249
11278835
|
AKT1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
17470458
18349820
29861848
16210317
21601007
17570479
11404460
22155408
12621049
14555644
11156376
|
AKT1
|
PDCD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
17053147
17081983
18296647
18187866
17287340
16357133
16964243
18669648
|
AKT1
|
GSK3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
110.0
|
1.0
|
Omnipath
|
15772344
19797085
23549785
20371716
11884598
25584893
11583116
11520785
14550568
19920184
15710331
21530327
9065430
16188907
24632852
12515807
11289110
24879152
20110348
12890758
15333638
14633703
11803463
16123357
8524413
21868755
12054501
23142783
25714023
16585200
15808505
22497526
16767165
19117997
14744935
19443725
21118801
18691976
18209096
11563975
17192257
11085518
19369195
19043530
11896604
10716737
19914182
19996208
21441927
32645325
15805282
21464307
34381779
16223362
12181443
15755769
11331582
11035810
21445305
27331409
16987514
11340086
15723049
22499768
18701488
11749387
20686112
11509608
19413330
20233866
15950778
20708687
14660586
17386267
11577096
15371448
11956225
12649200
16476742
11254732
21575859
14988390
11779850
19574224
20739666
17200115
|
CCND3
|
CDK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
11896535
25416956
16985050
34591612
21988832
14597415
17517622
16782892
10342870
21516116
23880157
15232106
16189514
11360184
26496610
25910212
26186194
27107012
10477583
19237555
32296183
14641107
9106657
9508775
31515488
9716181
|
MAPK9
|
ELK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
9130707
20506250
8846788
8654373
20028971
17875713
16393692
26538579
11145955
11309409
8887554
26370088
8548291
15782123
8262053
19436832
12665513
12947314
11274345
|
MAPK13
|
ELK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15187187
19436832
15140942
20506250
21614932
16393692
11274345
|
MYB
|
PDCD4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11470166
23606399
12082539
11313950
|
TFAP2A
|
ACHE
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
8610173
9571041
7559515
|
CEBPA
|
AFP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17188819
7549116
7518671
1377818
15924879
|
TFAP2A
|
CEBPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19089912
11688971
11050170
10588870
|
CEBPA
|
STAR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18583320
|
CEBPA
|
APOA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15109267
1900840
|
AR
|
UBE2I
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10383460
8798622
19692572
12764129
|
UBE2I
|
MYB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11779867
16713569
22910413
|
UBE2I
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10383460
8798622
19692572
12764129
|
TCF7
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17666529
23343194
21285352
18974774
22761862
22290435
16039586
19619488
19623618
17143292
|
TCF7L2
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17666529
23343194
21285352
18974774
22761862
22290435
16039586
19619488
19623618
17143292
|
TCF7L1
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17666529
23343194
21285352
18974774
22761862
22290435
16039586
19619488
19623618
17143292
|
LEF1
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17666529
23343194
21285352
18974774
22761862
22290435
16039586
19619488
19623618
17143292
|
AR
|
ETV1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17634427
19789348
20610535
17505060
|
CSNK2A1
|
HMOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14527438
|
CSNK2A1
|
RNF7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
16874460
12748192
|
CSNK2A1
|
ARNT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
16129408
18669648
|
CSNK2A1
|
MAPK9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11062067
|
CSNK2A1
|
NR1H3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16904112
18250151
25825525
|
CSNK2A1
|
TFAP2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21777522
|
CSNK2A1
|
LEF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
15747065
2861485
17113388
19623618
|
CSNK2A1
|
FOSB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16687504
17241283
|
CSNK2A1
|
MYB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
11522824
7735324
11313925
|
CSNK2A1
|
TCF7L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11711551
18452278
|
AR
|
STAR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
14673133
17065415
11595506
20537519
14630719
17400803
20924043
21971485
15590903
18974265
17909266
12943700
9801462
25001622
10403575
|
AR
|
KLK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
106.0
|
1.0
|
Omnipath
|
17433535
8626436
11059779
15640443
7686046
11006269
12111703
15368351
24307657
9316650
9719026
11867260
12376473
14767470
16275987
11994312
17075604
20181722
9211894
16342680
12917209
18092350
12648523
17011549
11238180
20069563
10547578
16140973
22245379
12539223
20568894
20103546
18758709
21981678
21541973
12463425
12958311
11894840
19389135
17534890
23662037
15923603
16434977
14517289
22695118
10075669
11377978
16137620
11299734
15131260
21780100
16508948
16425097
22473899
14715080
10625666
18640093
21885566
12670590
14729601
16452400
16081584
10898343
11571582
9044850
15833875
16914734
23884959
15640095
15543614
7514587
12376534
12114445
15557561
18780293
23667504
18829551
12782640
16724108
17426252
11504717
19274665
11034093
17566103
12651911
22179832
21308712
16373397
19013180
22155408
9052414
11532861
17094454
17653089
20709811
22654108
22597536
15514031
|
AR
|
MT2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11191077
20610535
17721441
|
AR
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18612129
16888681
20610535
|
AR
|
KLK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
1712248
19345326
25241761
|
HLA-A
|
CD8A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9177355
10809759
|
FOSL1
|
MMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22437631
18802113
25339983
10913304
14519134
21640141
|
FOSL1
|
IVL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15790882
11254751
17882273
7759510
17205062
10816578
|
ARNT
|
EPO
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8089148
10207038
20631191
11782478
8663540
8408001
|
ARNT
|
EDN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7539918
1823643
16716598
12829734
9159130
13130303
9588211
12080085
11566883
10403805
9746763
8943284
15451019
9278421
16887934
|
TFAP2A
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18980971
10589685
19853299
10506168
11739124
11773059
17666398
19939245
20145123
15317818
|
TIMP1
|
MMP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
19010413
12475252
|
TCF7L2
|
LEF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15473860
20802155
17335794
11326276
|
TIMP1
|
MMP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16189514
9063449
12475252
|
GATA1
|
EPO
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16471262
8677751
8288642
|
IL12A
|
IL12B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17145710
10779781
10899108
8943050
7527811
|
TFAP2A
|
ADM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10848972
9480831
17719138
8388865
|