CREB1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
9926942
6548521
|
BRCA1
|
CYP1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16567799
|
SP1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
GRB2
|
PPP1R9B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
SHMT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
MYC
|
SH3GLB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
MYC
|
SHMT2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18628958
|
MYC
|
ANGPTL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23617883
24039874
|
CREB1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20864035
|
HACD3
|
TNFRSF1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
SLC1A5
|
TNFRSF1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
UVRAG
|
SH3GLB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7216089
17891140
|
PRKAA2
|
PLIN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
26902588
25961502
|
LRRK2
|
UQCRB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
RELA
|
CFTR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11114294
|
RELA
|
PPARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10542237
16189514
|
PPARG
|
CYP7A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
|
PPARG
|
CYP1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18308446
15521013
|
LRRK2
|
MAP2K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19302196
|
SP1
|
KRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8887648
19994725
|
SP1
|
CYP27A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11867220
|
SP1
|
CYP7A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9875228
|
SP1
|
CERS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22169644
|
SP1
|
HSD17B1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9231796
|
SP1
|
ADH6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12004059
|
SP1
|
PDHA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8476854
|
CREB1
|
AANAT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10949537
16399907
|
CREB1
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16497991
16651461
|
RXRG
|
PPARA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
PPARA
|
PLIN5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23606724
17234449
|
PPARA
|
ANGPTL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15190076
12099716
|
PPARA
|
OLR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15381115
11795293
|
PPARA
|
ACOX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20813756
|
PPARA
|
ACOT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20813756
|
PPARA
|
ELOVL7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20813756
|
NR3C1
|
CYP1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9512490
2916850
|
NR3C1
|
RXRA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10860926
12573484
|
RXRA
|
NR3C1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12573484
23331499
|
NR3C1
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12573484
23331499
|
PLCB4
|
PLCB1
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
ACP1
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17353188
|
CYP2C8
|
SH3GLB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
COQ8A
|
SH3GLB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
AK8
|
SH3GLB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SH3GLB1
|
SPART
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PPARG
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
18509005
24735796
20360975
22282354
18310298
|
LRRK2
|
HACD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
24725412
|
RHOB
|
FRS2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
CFTR
|
ACSL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26618866
31324722
|
PPARA
|
RXRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16169070
22205725
|
RXRG
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RHOB
|
DHCR7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
RHOB
|
ACSL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
ACOT2
|
ACOT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
NDUFA1
|
UQCRFS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
HDAC6
|
CFTR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31501480
22069321
14675537
|
CFTR
|
RAB5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
26618866
21455491
19398555
|
ABCD2
|
ABCD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
24658140
10551832
|
ACO2
|
CKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
MYC
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
NR3C1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
PPARG
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
KRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
CFTR
|
HACD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
31324722
29924966
17110338
|
COX7A2
|
NDUFA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
ABCD1
|
ABCD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22939629
10551832
|
RAB5A
|
ACSL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
31980649
|
NDUFS3
|
UQCRB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
SP1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
14710355
16713569
12706836
10720440
17766039
|
MYC
|
ACACA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21150319
17353931
29467282
|
BRCA1
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
RELA
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
HRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
RXRB
|
PPARG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
20211142
22205725
15604093
25609649
30699358
|
PPARA
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
FRS2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
MYC
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16713569
11274368
18003922
17418410
15780936
32115405
|
SP1
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
18270252
10361124
10393239
16713569
|
HRAS
|
KRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
NDUFS3
|
UQCRFS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
MYC
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12646176
11916966
16713569
20215511
9788437
30415952
14612409
|
ACACA
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19061860
29899443
16713569
16326698
30257991
24565757
12360400
16698035
18452305
|
MYC
|
PDHA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
ACP5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
NRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
ACOX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
RPS6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
ACADM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
ACO2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
RELA
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12027803
16713569
|
MYC
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11274368
16713569
|
SP1
|
TNFRSF1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22019592
8954938
22615874
|
NR3C1
|
RELA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12734399
9261164
9442377
|
RELA
|
PPARA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20054868
10542237
|
RELA
|
TNFAIP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11880364
19343319
10807933
|
PPARG
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22363753
16189514
12763030
10944516
31547433
30404011
20211142
35140242
25609649
17312272
23703729
7838715
19047629
12966085
22205725
14587029
10882139
30595551
30699358
9065481
21833030
9568716
34081964
21478865
9121466
23275339
17579352
19147680
26260846
16713569
12591919
10854698
30651555
32929351
23711995
11877444
15888456
18217139
19043829
17980149
|
NR3C1
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
15531761
|
PPARG
|
NR3C1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
15531761
|
SP1
|
ACLY
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11989980
10618488
10801800
|
SP1
|
NR3C1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12039077
14962081
15249123
|
SP1
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7541039
|
MAP2K7
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17360977
|
RXRA
|
PPARA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
22205725
7760852
34081964
23711995
10195690
15888456
12562861
|
PPARA
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14751809
16842672
17105827
|
PPARA
|
ACMSD
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16807375
12944176
18320257
|
PPARA
|
ABCD2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11422379
14654352
17686565
|
PPARA
|
CYP27A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11701475
15340076
17156732
|
RXRB
|
PPARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8384714
23331499
11237216
|
RXRA
|
CYP1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15521013
|
AKT2
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24379783
|
GRB2
|
IRS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
ARID1B
|
SMARCE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
ACSL3
|
ACSL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
22939629
26496610
|
FRS2
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
16189514
8780727
16893902
22974441
21706016
10092678
9182757
11997436
25159185
15004239
12402043
34407391
|
IRS1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
7488107
8388384
7486683
8810325
22974441
21706016
8491186
7629070
12173038
8536716
|
ACACA
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
PPARG
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
PDHA1
|
PDHB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
BRCA1
|
ACACA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
16326698
19793801
20029420
21060331
21337561
25979092
|
BRCA1
|
ACACA
|
â—¼ PROTEIN_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
16326698
19793801
20029420
21060331
21337561
25979092
|
CREB1
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9528858
19882681
18160048
23447579
11704836
|
SP1
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15252835
17373631
18377656
19466541
|
MYC
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12032322
19882681
20940401
10375022
21668996
11916966
12646176
11983916
|
BRCA1
|
ACACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
16698035
19061860
12360400
24565757
18452305
16713569
16326698
|
IRS1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
8316835
8810325
9832424
8621421
8530377
9852124
9003010
|
GRB2
|
FRS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10982827
11274345
11447289
11777939
11997436
12040186
12175651
12640133
14585353
15173823
15567848
15574420
15863030
16102570
16488589
16582911
16887996
17496910
17673906
19449109
19568798
24027568
25772309
26552706
6321473
7510700
8551221
|
HRAS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
KRAS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
IRS1
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
10086337
10826997
12175651
12444011
12767520
16931767
17604717
19030972
21540285
22465479
24036369
8621421
|
NRAS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
GRB2
|
FRS2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10982827
11274345
11447289
11777939
11997436
12040186
12175651
12640133
14585353
15173823
15567848
15574420
15863030
16102570
16488589
16582911
16887996
17496910
17673906
19449109
19568798
24027568
25772309
26552706
6321473
7510700
8551221
|
GRB2
|
MAP2K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10982827
11274345
11447289
11756498
11777939
12040186
12175651
12640133
12738796
14585353
15567848
15574420
15863030
16102570
16582911
16887996
17496910
17673906
18000759
18855897
19151919
19449109
19568798
21614932
24027568
26552706
27331412
7510700
8551221
|
GRB2
|
FRS2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
30.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10982827
11274345
11447289
11777939
11997436
12040186
12175651
12640133
14585353
15173823
15567848
15574420
15863030
16102570
16488589
16582911
16887996
17496910
17673906
19449109
19568798
24027568
25772309
26552706
6321473
7510700
8551221
|
IRS1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
8265614
7862167
11788580
8388384
8491186
8536716
7488107
7486683
10358772
10592173
8196603
12173038
12679424
8114695
11259577
8810325
|
FRS2
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
8780727
9182757
12974390
11997436
16189514
12402043
|
GRB2
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17496910
16713569
17673906
11352655
|
MYC
|
GPI
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10823814
11274345
11283613
11283614
11704864
16126909
17055429
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
25002027
28536364
|
MYC
|
PPARG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10432118
11274345
11283614
11875494
16327802
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21093321
21372296
21406394
21765015
2191300
22067385
22461508
23124025
23390297
25002027
|
MYC
|
SLC1A5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
11274345
11283613
11283614
11704864
17055429
17558397
17873522
19033189
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
25002027
28536364
|
RELA
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
12894581
18184402
7869034
17673602
12783888
11114727
17944672
9596659
19469019
21790895
19766095
17018379
8289784
18566231
|
PPARG
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11973610
17462534
16405739
19075513
|
SP1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11470523
9492315
2284094
8437848
7753559
8355712
2057364
|
MYC
|
TSC2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18056446
12695333
|
TNFRSF1B
|
MAP2K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
11274345
12556535
12655147
12738796
15592525
17462996
18641653
18855897
19392652
21133840
21232017
21614932
23850759
24378531
|
SH3GLB1
|
UVRAG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18032918
17891140
21068542
|
CAMKK2
|
PRKAA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
16051629
22561688
21228273
34044797
24959379
17244528
15980064
23716691
25065674
15465812
34421352
12413941
19197243
18692468
33502468
34216621
23863464
34064003
16054096
16054095
15509864
33675805
20538596
19958286
25937278
34290400
34253170
23612973
22304913
|
PRKAA2
|
ACACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
35.0
|
1.0
|
Omnipath
|
19651622
11052978
20166139
9029219
18669648
18767875
2900138
12015362
20068231
18707149
19061860
17519230
7907095
7915280
29899443
16326698
18212344
|
PRKAA2
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18692468
16959574
19339977
14651849
|
PRKAA2
|
ACACB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
14532170
12488245
9148944
20166139
12413941
14613924
|
AKT2
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
12150915
12167664
12172553
19188143
|
HRAS
|
FRS2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
SP1
|
HRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
8106522
8208618
3012774
11559711
21931711
8027084
1776841
|
NDUFA1
|
NDUFS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFA4
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFS3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA4
|
NDUFS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA4
|
NDUFS3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
CREB1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
11579131
12417340
15079071
15187187
15279786
15337521
15536066
16007092
16713974
17303408
17550372
17565603
17660363
18590585
19171876
19879327
20144767
23430059
7575488
8383323
9743347
|
CREB1
|
RELA
|
â—¼ PROTEIN_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
11579131
12417340
15079071
15187187
15279786
15337521
15536066
16007092
16713974
17303408
17550372
17565603
17660363
18590585
19171876
19879327
20144767
23430059
7575488
8383323
9743347
|
CREB1
|
RELA
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
21.0
|
1.0
|
ACSN
|
11579131
12417340
15079071
15187187
15279786
15337521
15536066
16007092
16713974
17303408
17550372
17565603
17660363
18590585
19171876
19879327
20144767
23430059
7575488
8383323
9743347
|
SP1
|
RELA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
7636984
8450395
9151857
20538607
11964305
|
RELA
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18397880
14570928
17081374
|
NR3C1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
23871663
10995388
7659084
8290595
16713569
|
RELA
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12055073
7933095
10671503
20861353
|
RELA
|
NR3C1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
23871663
10995388
7659084
8290595
16713569
|
PPARA
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12941763
16226723
20706641
17261671
18769491
|
NR3C1
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
24811171
27777311
10649448
8754811
11279134
|
PPARG
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15590897
19666848
19732722
16020752
|
PPARG
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16269451
15111490
15908479
11777901
|
PPARG
|
ANGPTL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14570927
15190076
23518684
19934321
|
PPARG
|
PLIN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16403437
17322100
15764152
11420178
19383873
20950277
19571381
14671211
20030713
15827101
|
RXRA
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
12763030
25609649
20211142
11877444
16504037
17579352
16713569
9065481
22205725
23331499
22363753
10854698
19147680
19043829
12591919
9568716
10882139
10935544
17980149
26260846
21478865
14587029
23711995
9121466
18217139
31547433
7838715
19047629
23275339
21833030
12966085
17312272
11237216
15888456
|
RXRB
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
22205725
25609649
23331499
20211142
15604093
11237216
18988627
10882139
|
PPARG
|
RXRG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
12615696
16189514
18988627
15130092
|
SP1
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
12759366
19105596
15722551
18624763
12684688
9614091
10574932
10713142
15061658
12270858
15180995
|
SP1
|
ACACA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9240931
8576128
9271397
8663083
|
KRAS
|
FRS2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
NRAS
|
FRS2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
CREB1
|
TH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16893419
10407170
15240392
20367754
11238722
16452470
9645965
11108136
9038229
|
AKT2
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
19216069
17680028
11756412
16680151
20214616
11463845
20452955
9829964
20398329
17646672
10217147
|
NR3C1
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
20203101
16713569
8449898
7621901
|
AKT2
|
AKT1S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
17329361
19651622
17081983
17386266
17517883
12524439
11352916
20068231
18372248
19413330
17277771
14973226
18669648
23682635
|
PPARA
|
CYP1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21304969
15521013
|
PPARA
|
ACOX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8567672
7635967
9556573
20110263
16828988
|
PPARA
|
ACSL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19710929
10777552
17150915
23426369
|
PPARA
|
CYP7A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
10744771
11042130
10777541
17660447
14960721
|
RXRA
|
PPARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
10195690
12562861
16189514
11237216
10708554
|
PPARA
|
RXRG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22205725
23331499
16169070
15130092
|
RXRA
|
CYP7A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
19106115
20338915
16049268
|
PEX12
|
ACAA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
8858165
24865970
10022913
26138649
9653144
11546814
|
PEX12
|
PHYH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
8858165
24865970
10022913
26138649
9653144
11546814
|