Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
AP2M1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
CD44 ARHGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12748184 16189514
EGFR KPNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20692258 7987951
EGFR PTPN1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 9355745 6671413
KPNA1 CSNK1A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12062430 5215475
PDE6D RAB18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ADAM9 PACSIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10531379 5211924
JUP PTPRJ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12370829 6671521
PRAF2 ARL6IP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217589 15757671
ARL6IP5 PRAF2 â—¼   COLOCALIZATION 2.0 0.8 intact 5217589 15757671
PRAF2 CANX â—¼   COLOCALIZATION 2.0 0.8 intact 5217589 15757671
ARHGEF11 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN DAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
GNAS ADCY3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9228084 21406690
JAK1 ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB2 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16273093
ARL6IP5 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
HLA-C B2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211709 10429675
RAC1 RAB35 â—¼   COLOCALIZATION 2.0 0.8 intact 19289122 7012064
NGFR RHOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9195882 12692556
CNKSR1 RHOA â—¼   PROXIMITY 2.0 0.8 intact 15670823 5217486
RHOA PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16644720
PDE6D CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CDC42 RAB35 â—¼   COLOCALIZATION 2.0 0.8 intact 19289122 7012064
PI4K2A ITCH â—¼   COLOCALIZATION 2.0 0.8 intact 23146885 8426259
ARHGEF2 RHOB â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16917499 18287519
INSR PTPN1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 11506178 6671880
RHOB INSR â—¼   COLOCALIZATION 2.0 0.8 intact 14722096 6672086
DAAM1 PFN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17021034
GNA11 GNB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25675501 15889144
CANX MRPL16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CANX HERC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PTPN1 RAP1B â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16005629 16115959
PTPN1 RHOB â—¼   COLOCALIZATION 2.0 0.8 intact 14722096 6672086
GNA11 PLCB4 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
CDC42BPB MSN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10947843
FBN1 MFAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
LRRC8D LRRC8A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1252826 24790029
CAV2 EGFR â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
EGFR JUP â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CHCHD3 IMMT â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
RHOB CD44 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
CD44 CLCN7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RHOB EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB OPA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
CD81 GNA13 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32900848 30024968
CD81 RHOB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32900848 30024968
MYL6B RAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 27173435
RHOB JPH1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB EHD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB HIP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
HIP1 AP2B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 15533940
DAB2 AP2B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22323290 34079125
RAB2A RAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
RAC1 FAT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
RAC1 PHB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
PTPRF RHOA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 25458010
RHOA FAT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
RHOA RAP2C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RHOB LRP6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
CDC42 RAB1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
CDC42 DAAM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 16630611
RHOB FRS2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB MINK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB RAB23 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB ADCY9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RAB1A RAB2A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26344197
RHOB DDX18 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB NSF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB ECT2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB HIP1R â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB BMS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB DDX56 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB DDX52 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB CLCN7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB MPZL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB CNNM3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB PKP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB DOCK9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB RELL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB EPHA7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB PANX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB ADCY3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB PALM2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB DHCR7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB ANO6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB DSC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB DGKD â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB ATP7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB EHBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB ACSL4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB NCLN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB PODXL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB CEP89 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB EFR3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB PALM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
CDH2 CTNNA1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
CXCR4 ITCH â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
ARHGEF1 RHOA â—¼   GTPASE_REACTION ✅ + 0.82 0.82 Signor 10836144
HIP1R PICALM â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
PTPRK EGFR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
GNAI2 MCU â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CXCR4 GNA13 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11994484 23773523
PTPRK ADAM9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DAAM1 RHOA â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
AP2B1 CLTC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
EGFR CD44 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11606076 16565089 12093135 15597342 23265944
MAP1A RHOB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18056259 19637314
GNAI2 GNB4 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
EHD2 AP2M1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16713569 15182197
EGFR AP2B1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24797263 24189400 7534311 23956138
ARHGEF11 PLXNB2 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CD81 EGFR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32900848 30024968
CD81 GNA11 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32900848 30024968
CD81 GNAI2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32900848 30024968
FYN PTPRF â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12496362 31413325
RAB5C CLCN7 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
ARHGAP35 RHOA â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
EGFR PTPRF â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24797263 31980649 24189400
RHOA ARHGEF11 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 7909059 20300064
FYN CD44 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9573028 16189514 16713569
IL6ST JAK1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CDC42 RAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
DOCK9 CDC42 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 12172552
RAP1B CDC42 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 26344197
INSR PTPRK â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 26186194 33961781 19167335
RAB5C RAB1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 26344197
COBL PACSIN3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
EGFR AP2M1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24797263 20029029 31980649 24189400 23956138 24067654 25754235 31959764
CD44 ERBB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11606076 28628118 12093135 17092940 28205554
PTPRJ EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19836242 9115287 19167335
HDAC1 PHB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 12466959 14637159 16964284 17932104 27025967
RAB1A RAB8A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26824392
RAB2A PHB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 26344197 26496610
CDH2 JUP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
ARHGAP35 RHOA â—¼   GTPASE_REACTION ✅ - 0.89 0.89 Signor 32203420
EGFR PTPN1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CLTC HIP1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
RAB1A RAB8A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
AP2B1 AP2M1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12086608 16189514 16713569 24189400 33961781 19380743 26186194 30021884 34079125 26344197
PICALM CLTC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16491119 10436022
PTPN1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 6671413 9355745
EGFR RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
EGFR CAV2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 15273741 25402006 16799092
EGFR ERBB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11500850 25241761 30898150 17486068 11526509 9461599 23866081 17426253 10572067 11500516 24557338 8665853 15657067 19060928 16516204 19650109 20211985 25315821 23436906 21278786 25898135 32669362 1346931 24189400 21044682 18803307 16843263 28369073 7531698 16713569 17148612 21203579 17307140 1706616 16207817 7797556 12354693 11408594
PTPN1 EGFR â—¼   PHOSPHORYLATION ✅ 0.9 0.9 mint 6671413 9355745
PTPN1 EGFR â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 6732094 9050838
EGFR PTPN1 â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 25796184
PTPRK EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16263724
EGFR JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8524316 15284024
FYN ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18541700 23144976 11536198
GNAS ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690
GNAS ADCY9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
RHOA ARHGAP35 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18829532 9407060 16308318
ARHGAP35 RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 12429740 16707504
ARHGAP35 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 10592173 32203420
ARHGAP35 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 1894621 10873807 32203420
HIP1R HIP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11063258 33961781 11889126 28514442
PTPN1 CDH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9786960 11106648 12377785
ERBB2 RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
DAAM1 RHOA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25241761 31871319 11779461 33961781 16630611 18218625 18162551
ARHGEF11 RHOA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
RHOA PFN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22820501 22479341 27228149
CANX B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14681859 2450918 10064069
NFKB1 B2M â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12480693 2196446
CXCR4 ITCH â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19116316 34927784 24489825 28264927 22275353
ARHGEF11 RHOB â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
GNA13 ARHGEF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11799111 10026210
RAP1B PDHB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GNA13 ARHGEF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11313914 15951850 22661716
ARHGEF11 RHOA â—¼   GTPASE_REACTION ✅ + 0.91 0.91 Signor 32203420
CTNNA1 JUP â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
CANX GANAB â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ADCY9 GNAS â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
HDAC1 NFKB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 12972430 17962807 24448807 11931769 14678988 16319923 17827154
PDHB PDHX â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ARHGEF11 RHOA â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
PTPN1 INSR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 12634852 6671665
PTPN1 INSR â—¼   PHOSPHORYLATION ✅ 0.98 0.98 mint 6671880 11506178
PTPN1 INSR â—¼   PROXIMITY ✅ 0.98 0.98 mint 16926280 6671607
INSR PTPN1 â—¼   PROXIMITY ✅ 0.98 0.98 mint 12634852 6671665
PTPN1 INSR â—¼   DEPHOSPHORYLATION ✅ 0.98 0.98 mint 17481567 6732036
INSR PTPN1 â—¼   DEPHOSPHORYLATION ✅ 0.98 0.98 mint 6764581 15588987
B2M HLA-C â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
INSR PTPN1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MRPL16 MRPS5 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
AP2B1 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2M1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23956138 31980649 24189400 19351721 20029029 24797263
NFKB1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14678988 18367518 12469217 17881446
PTPRJ EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19836242 9115287 19167335
EGFR PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 25796184 31980649 8621392 12573287 18253097 11106648 11506178 24658140 7540771 9050838 9355745 15982634 25402006 10889023 7693694 8999839
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
NFKB1 RBX1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
FYN JUP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14517306
ITGAV ITGB5 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
ITGAV ITGB5 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
JAK1 ITGB5 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
ITGB5 ITGA2 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 22470492 24309651 26519775 9295024 9763615
ITGB5 ITGA1 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 22470492 24309651 26519775 9295024 9763615
ADAM9 ITGB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11162558
CDC42 ARHGDIG â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16714282 7512369 9113980 23434736 11306516
ADAM9 ITGAV â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15361064 11162558
ITGA5 FYN â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
FYN CDK5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 24872417 19901323 9038181 10896159 18691976 20506281 29063113 20068231 16497976 19413330 14757045 12372285
FYN ITCH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16387660 17053785
FYN PTPRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12496362 18854310
JAK1 IL6ST â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8390097 9238703 16051226 11943154
JAK1 IFNGR1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 IFNGR1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
IL6ST JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7896787 23331499 11468294 9388212 21220115 24710148 11742534 23663276 12487370
JAK1 IFNGR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12133952 8232552 8550631 8156998 7796299 7615558 8649432 19041276
ADAM9 ITGA6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15361064 10825303
ARHGAP35 RHOA â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 17517963 18829532 22411312 8360177 9819392
NGF NGFR â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NGF NGFR â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NGF NGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 10764727 11729324 16893414 2172988 1372492 24224055 14985763 22227462 11114882 15258592 14699954 3037029 1714587 9775403
RAC1 DOCK9 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15710388 15247287 12134158 17196961 17027967
ARHGEF2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11595749 16189514 9857026
RHOA DAAM1 â—¼   PHYSICAL_INTERACTION 53.0 1.0 ACSN 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605
RHOA DAAM1 â—¼   SHARES_COMPLEX 53.0 1.0 ACSN 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605
CXCR4 RHOA â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15261139 15882617 17035340 20535745 20644254 21521526 22025564 23034983 23402812 23567181 24277834
DAAM1 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11779461 25241761 18218625 20810787 19365405
ARHGEF1 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9789025 12748184 32203420 9113980 9641915 10836144 11149925
ARHGEF2 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 9789025 22072711 32203420 9113980 9641915 10592173 9857026 20810787 16189514 24525234 11149925
ARHGEF18 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11085924 20810787 18256687
ARHGEF11 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 21988832 32203420 20300064 15530360 10526156
ECT2 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9789025 32203420 9113980 9641915 15774750 11149925
RHOA MSN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9856983 15659383 11867620 35267019
DAB2 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 20460648 21498506 21304492 19561074 22491013 15518237 19581931 17318175
CSNK1A1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 25301071 23331499 21887268 16890161 27821587 14731402 24794231 25735981 20229235 16341017
DOCK9 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9490022 9113980 10816584 17045588 8836113 12172552
ECT2 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15642749 9490022 9113980 10816584 17045588 8836113
ITCH CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28264927 19116316 24489825
CXCR4 GNAI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520
NFKB1 PRKACB â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
PRKACB NGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12682012 26119933
PTPRJ INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1715686 10734133
PTPN1 INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 10066179 12612081 11163213 17092689 11506178 15632081 8826975 8702689 16926280 14722096 8999839 23331499 8244979 15588987 11579209 16271887 10592173 1599438 9355745 11726652 12237455 10751417 17481567 21806020 19029027 1321126 12634852 11850117 10852715 15192089 10807907 16582879 17159996
PTPRF INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 23331499 7852302 10734133 15588985 11158333 10592173 1321126 8732688 19910497 8995282 1303753
ARHGEF11 ERBB2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12220504 15210733 12196628 12730235
PFN1 DAAM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18798527 19523939 17373907 17021034
GNAI2 ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
GNA13 ARHGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14607242 9641916 9641915 16189514 12681510
CSNK1A1 RHOB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 27503856 18590726
PDHX PDHB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632