Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CASP9 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CASP3 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 12011067 15573119
XIAP CASP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11242052 5213680
XIAP CASP9 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
APAF CASP3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 21827945 11550094
XIAP CASP3 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 9525868 6547707
APAF XIAP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11242052 19698783
WDFY3 APAF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DEFI8 APAF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
K1683 APAF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
APAF HS90A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10934467 15001356
OMD APAF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DEFI8 WDFY3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NALP1 CASP9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11113115 11076957
ENDOV APAF â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PP1A APAF â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17274640
CASP9 CASP3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11242052 8900201 25241761 1067155 15941357 11230124 15507451 18723680 17437405
CASP9 B2CL1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9539746 16189514 25241761
B2CL1 CYC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9192670 16189514 25241761 16713569
NALP1 B2CL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19223583 17418785
APAF B2CL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9539746 9488720 12963020
APAF NALP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17418785 11113115
CASP3 CASP9 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
APAF CYC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9267021 16713569 16979168 12147322 10206961
CASP3 XIAP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 25241761 11447297 9525868 11257230 19698783 9384571 22815893 15507451 16869888 17291493 15200957 27927753 19273858 18723680 16543147 23074197 11927604 18521960 30522111 23979166 17069460 12624662 15650747 11257232 11359776 33961781 26186194 22072751 9230442
CASP9 XIAP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 25416956 25241761 19698783 9545235 15507451 11801603 17291493 19153467 11242052 32296183 15280366 15749826 31467278 16701639 17179183 15300255 23074197 11390657 11927604 18022362 27107012 30522111 14512414 12620238 29997244 25502805 14523016 15069192 16322207
APAF HSP74 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22143029 10934467 31577950
B2L10 APAF â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 9878060 10486928 9829980
HS90A HSP74 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 27708256 27187154 18620420 16314389 33571422 21360678 18408180 26344197
XIAP CASP3 â—¼   UBIQUITINATION ✅ - 0.94 0.94 Signor 11447297
PP1A B2CL1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 12115603 17274640
CASP9 APAF â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 27197231 9390557 9878060 19698783 28716524 15262985 11242052 19494828 16979168 9922454 9488720 9539746 20462491 10376594 11113115 21060833 21827945 9837928 27476169 20829884 10206961
CASP3 XIAP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CASP9 XIAP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CASP9 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10708865 9390557 10508159 11230124 18723680 15657060 16977332 15507451 1067155 9708736 25241761 8900201 11242052 9765224 17437405 19788417 9812896 12620238 15941357 12181739 19465923 12792650 15725726
XIAP CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 23074197 16543147 22072751 12624662 18521960 22815893 11157976 15650747 15200957 11927604 11230124 9384571 16869888 9545235 23979166 18723680 16189514 11359776 15507451 9230442 19273858 26186194 10508158 25241761 12529384 19559631 11257230 12874265 9525868 17291493 11583623 11257232 17069460 12181739 10548111 11447297 15014070 19698783
XIAP CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 62.0 1.0 Omnipath 15069192 15280366 25416956 18022362 11157976 31467278 15200957 11927604 11230124 12042762 16322207 9545235 11801603 25502805 14512414 16189514 15300255 15507451 10508158 25241761 27107012 14523016 17179183 16352606 11242052 32296183 16701639 17291493 12620238 15749826 12181739 11390657 29997244 31515488 23074197 19698783