Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SP1 COL1A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19558215
LZTS2 BGN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP TNF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BGN HSPB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 26465331 0133994
HSPB2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP3 CD14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11698458
SP1 COL18A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11093745
SP1 BMP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21411747 17350185
DSN1 BGN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP3 ELN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8910531 12055073
SP3 BGN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9786935 15372625
JPH3 BGN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ELN MFAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6123066 16906757
SP3 SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15247906 11517158 10825178 16734381 9329821 12414801 12200149 23825960
TGFB2 TGFB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27684187 11483955 33961781 11157754
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
TLR2 CD14 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18765807 10395652 16189514
TGFB1 BGN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10383378 16189514 8093006
THBS1 TGFB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22943793 8349738 21900405
THBS1 TGFB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22943793 8349738 21900405
SP1 ELN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12055073 21880723 7896792
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
SP3 COL1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9666093 10082137 17698844
SP1 COL1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 10091149 16575855 9666093 10775443 12138160 11348466 17698844 16564026 10082137 7504695 7590335
SP1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 23733894 12759366 27030318 22534375 7649977 12509451 12378384 15175554 18357389 10829018 11390427 17897957 18218727 8258705 12560487 17047073 21320120 7918637 16847329 10559188 18930140 20068037 1618817 21784970 10688670 10913190 17307735 18467438 21411747 11500175 20221720 20701940
SP3 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14555463 12759366 19109523 11390427 11500175
THBS1 TGFB1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10657674 11982756 14568985 14996710 21900405 22943793 8349738
SP1 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12186868 9580699 2808430 12615726 22415074 27974707 12138160 10964912 9242631 15178441 23437118 23936544 11114293 8325508 16714330 11278686 10212284 9837963 11054406 23806282 15979845
THBS1 TGFB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22943793 8349738 21900405 1550960
TGFB1 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12867422 25241761 16189514 2119582
TLR2 CD14 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16455995 17889651 10426996 15241424 16880211
TLR4 CD14 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 22078883 16467847 22158869 18233961 18297073 14517279
SP1 CD14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11698458 17203216 12213324 7512565
CD14 TLR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11745332 17535871 12196527 32196115
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
SP1 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19049493 8427604 15673661 9361293 21557719 18449948 14701757 8015372