Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CDK2 HACD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0205180 30300385
EIF4G2 APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11943866
XIAP APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11230124 12181739
NOD2 CASP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0802726105 18511561
NOD2 CASP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0802726105 18511561
TSHZ3 CASP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19343227
STAT1 CASP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21530491 12198138
GSN CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EIF2S3 EIF4G1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
EIF3A EIF4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 17353931
EIF4G2 XIAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11943866
VDAC1 GSN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17254575 5219552
IL37 GSN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
XIAP NOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19667203 0907131106
XIAP NOD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19667203 0907131106
PSMD6 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SMC4 SMC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17268547 5219584
VDAC3 VDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EIF2S3 EIF4A1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CASP8 TRAF6 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
CASP5 CASP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CDK2 MYH9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 21319273
SMC2 SMC3 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CASP1 GSDMD â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
NOD1 CASP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12459189 10329646
TRAF6 CASP8 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16436380 27810922 16920630 30979779
NOD2 XIAP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22607974 23818254 19667203
EIF4G2 EIF4G3 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
TRAF6 PSMD6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 17353931
EIF4G1 EIF4G3 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
EIF3A EIF4G1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CASP1 NOD2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15107016 18511561
CASP10 CASP8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CASP4 GSDMD â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
VDAC1 VDAC3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30021884 31536960 22939629 29128334
EIF4A1 EIF4G2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
CASP1 IL18 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 1574116 9121587 8999548
CASP4 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12843244 9491891 9039262
SERPINB9 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10477277
CASP1 IL37 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12096920
CASP5 IL18 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9121587 17039247
EIF4G2 EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10394359 16467844 10944120
EIF4A1 EIF4E â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
SMC1A SMC2 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
SMC1A SMC3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
EIF4A1 EIF4G3 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
SMC2 SMC4 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
EIF2S3 EIF3A â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
EIF3A EIF4A1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
EIF4G1 EIF4A1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219000 16932749
SMC3 SMC1A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24981860 22939629 26496610 31807710 30021884 21880767 17112726 10931856 26344197 11590136 12759374 17349791 9789013 23242214 11877376 18832153 27173435 31010829 11076961 22885700 21111234 17113138
EIF4E EIF4G3 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PSMB1 PSMD6 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CTNNB1 CTNNBIP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
EIF4E EIF4G1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
EIF4A1 EIF4G1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMC2 SMC4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SNRNP200 SNRPA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMC1A SMC3 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
NOD1 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10329646 12459189 9705938
STAT1 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17339457 17085014
CASP1 IL18 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22270365 17039247 15326478 9121587 9334240
CASP1 CASP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11051551 11536016 11432859 15383541
CASP8 CASP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 22864571 17159907 17145710 12887920 11832478 11717445 21737330 15280356 12198154 3031469 15659383 170210 8962078 22421964
CTNNBIP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 17145710 26912724 17353931 12417602 15893313 20211142 18287330 17072306 21885566 12408825 12408824 10898789
EIF4E EIF2S3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF4G1 EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17145710 8521827 22509910 17689282 23665581 22586265 16648488 16467844 9372926 16541103 15361857 16720573 9418880 16281055 18955708 12071973 21191102 26186194 10753870 15153109 10600798 7651417 20212144
MSH6 MSH6 â—¼   KO_DOWN_REGULATES ✅ - -5.12 5.11 PKG 28854368