Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CHEK2 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
MDM2 ATM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19816404 21986495
CHEK2 ATM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
ATM SMC1A â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 11877377 5215162
ATM HERC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20023648
ATM PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12147700
SYCP3 BRCA2 â—¼   COLOCALIZATION 2.0 0.8 intact 22116401 8303438
CDC25A CHEK2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 11298456 5213933
FGFR3 CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK2 CDC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
CDK2 MCM7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
CDKN1B CCND2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PAX6 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20053773 17157287
SOX2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22469032 22855803
FLT3 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28522571
MYC CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24704206 26701207
CHEK1 RB1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17380128 5219804
HERC2 CHEK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
HERC2 CHEK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
RB1 CHEK2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17380128 5219804
CHEK2 MDM2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15862297 5217705
CHEK2 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32187724
TCF7L2 COPS5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
COPS5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18926707
COPS6 CDKN2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DOT1L CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000539 21103407
NFKB1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
EP300 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374512 11433299
PRKDC HERC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20023648
PLK1 MAGED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MAPK1 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK1 RPS6KA3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8941362
MCM7 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
E2F2 MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14990995
E2F2 MCM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 14990995
RB1 MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218170 16374512
MYC TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
MYC PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15197457 12420224
MYC TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15466196 12080469
E2F2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11564866 18319725
RB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7838535
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
FGFR3 NSMCE2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NSMCE2 TERF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19308705
RAE1 NUMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17172455 0609582104
CCNB1 NUMA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7769006 23921553
CCNB1 PDS5A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CCNB2 PDS5A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CCNB1 PDS5B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CCNB2 PDS5B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
PLK1 CDC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21041660 1013557107
E2F2 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18439978
PLK1 CDC6 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 21041660 1013557107
PLK1 SMC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11970886
H3C2 PRKDC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
CSNK2A1 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20711232
RAD21 SSU72 â—¼   COLOCALIZATION 2.0 0.8 intact 8080148 20818333
SMC1A RAE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18832153 0807660105
H3C2 RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
SMARCA5 KNL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19410539 19398759
SMARCA5 H2AFX â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19092802 19234442
CDCA5 SMC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17349791
SMC3 MXD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9528857
SMC3 MXD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9528857
MAD1L1 SUPT5H â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GOLGA2 SUPT5H â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
SUPT5H GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
HNF4A TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20621834 16771709
IRF2 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9625761 18802049
HDAC1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18691180 9650586
PCNA CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16713569 9667749
CDK6 MCM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
E2F2 CDKN2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12077144
LHX2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19146846 24262147
CALM3 CAMKK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9822657 10187789
CALM3 PPP3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15757646 293720
BECN1 USP13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21962518 22216260
SMAD4 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
SMAD4 GADD45B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14630914 12933797
CREBBP SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9679056 9679060
SMAD4 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9679056 9679060
RPL37A TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TGFBR2 RPL37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
MTA1 HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23791785 16511565
RB1 HDAC1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
RB1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211419 10228159
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
CDC6 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
E2F2 CDC6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12411495
E2F2 CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766737 18319725
CCNB2 MCM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
MCM2 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
MCM2 CDK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
NFKB1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
CREBBP H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
ETV3 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18025162
NFKB1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19027835
NFKB1 CTCF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21912613
NFKB1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21790895
PPP2R1A CDK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
CDK4 CCND2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
PKMYT1 TGOLN2 â—¼   COLOCALIZATION 2.0 0.8 intact 23241949 8412360
PRKCA RPS6KA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16810323 5218785
PRKCA HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15367659
GOLGA2 TRIM29 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
BUB1B HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7299731 19407811
PRKACA RPL37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2R1A ANAPC10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
CCNB1 CDCA5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CCNB1 WAPL â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
MXI1 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11875718
E2F2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15510213 18319725
CCNB2 WAPL â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CCNB2 CDCA5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
MECP2 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ANAPC1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8638126 9556553
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
ANAPC10 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 ANAPC10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC10 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 ANAPC10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
PRPF6 PRPF31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNF4A TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951069
MAD1L1 MAD2L1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
H3C2 RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
MXD1 MAD1L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12876282 19526459
MBD2 MECP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11865062 20886097
PAX6 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23622063 15558475
H3C2 MBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14610093 10471499
TRIM29 MAD1L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MYB PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9371644 7838532
CCNA2 PCNA â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ATM CHEK2 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 10973490
HDAC1 SMARCA5 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
SNRNP200 SRRM1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CDK2 CDC25A â—¼   PHOSPHORYLATION ✅ - 0.81 0.81 Signor 17110335
CDC25A CDK2 â—¼   DEPHOSPHORYLATION ✅ + 0.81 0.81 Signor 22263797
NFKB1 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11739381 23811396 14662860 12471036 20065107 22013068 12960163
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
CDK6 MCM2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15232106 16189514 16713569
CDCA5 PDS5B â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
PLK1 BUB1B â—¼   PHOSPHORYLATION ✅ + 0.81 0.81 Signor 23079597
SF3B1 SRRM1 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
SF3B3 SRRM1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
AURKB NDC80 â—¼   PHOSPHORYLATION ✅ - 0.81 0.81 Signor 20471944
CEP63 NDC80 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 32296183
EP300 KLF8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 20107328
CUL3 MCM7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 26188516
RAD21 MCM7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22145905 26344197
MXI1 MYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 7565735 32140074
MBD3 MYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24048479 30415952
SF3B1 MYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29467282 20936779
MYC RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC DDX47 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC SMC1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC SMC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC PRKDC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC GNL3L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RBM15 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29467282 26496610
FEZ1 PLK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NFKB1 PRKDC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14743216 25609649
RAD21 PRKDC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22145905 22939629
EPHA1 PRKDC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SMC2 RAD21 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22145905 17113138
CUL2 SF3B3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23951410 21145461
CUL3 SF3B3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23951410 21145461
SF3B3 SMC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 31010829
SMC1A CTCF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18219272 33196849
DISC1 SMC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 17043677
CDCA5 STAG1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26496610 31010829
EPHA1 STAG1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MBD3 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 25123934
BUB1B HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28985013 19407811
CDCA5 WAPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26496610 31010829
EPHA1 SMC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MBD2 MTA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
SOX2 MTA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21532573 23667531
SOX2 RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21532573 23667531
MECP2 BAZ1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SOX2 TEAD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
SOX2 MBD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24048479 21532573
EPHA1 HOOK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FOXC1 NFIX â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 25609649
ATM CHEK1 â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 20068082
CCND2 RB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
SMC3 CEP63 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
CCNA2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PDS5A PDS5B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 17112726 26344197
STAG2 PDS5B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15855230 29867216 17113138 31010829
RAD21 DISC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
SF3B3 SMC1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 26344197 31010829
SMC2 SMC3 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
CDCA5 STAG2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 21987589 26496610 33961781 26186194 29263825 31010829
SMC2 DISC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
RBBP4 MTA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 24981860
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
MCM7 RB1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HDAC1 SFPQ â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CSNK2A1 HDAC1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
STAG1 STAG2 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
TUBA1A TUBB â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CCNB1 CDK7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 33961781 26186194 11113184
CCNA2 CDK7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 11113184 33961781 26186194 16327805
SMC3 MXI1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9528857
PCNA CCNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 7903056 33961781 8101826
MTA2 HDAC2 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 6613464 18451879
CCNB1 CCNB2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19879842 26344197
CCNB1 PKMYT1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CTNNB1 IQGAP1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ANAPC2 BUB1B â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ANAPC10 FBXO5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
EFTUD2 SRRM1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
EP300 PRKDC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
EP300 MCM2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
CDCA5 RAD21 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21111234 28514442 21987589 26496610 15837422 33961781 26186194 31010829
MTA1 HDAC2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6613464 18451879
CDK6 CDKN1B â—¼   PHOSPHORYLATION ✅ - 0.85 0.85 Signor 16160006
HNRNPU POLR2A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CDK6 PCNA â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
MBD2 RBBP7 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
CHD3 MBD3 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
SSU72 POLR2A â—¼   DEPHOSPHORYLATION ✅ + 0.85 0.85 Signor 15125841
HDAC1 MECP2 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
ATM PRKDC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10608806 10464290
CDK2 CDC6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9566895 9889196 10339564
SMAD4 EP300 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 25514493 18215124 9843571 14612423 10887155 22033265
MYC PDS5A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 29467282
BUB1B PLK1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17376779 19503101 28410192 26323689 23455478 24067371
SMC1A PLK1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 27173435 26344197
PLK1 MCM2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15654075 27173435
CUL3 PRKDC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26949739
HDAC9 HDAC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12590135 16611996 10487760 10655483
SOX2 CHD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23667531 28794006
ANAPC1 FBXO5 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
CREBBP MDM2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CDCA5 PDS5A â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CCND2 CDK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9840943 28514442 33854235 33961781 26186194 23455922 9178893
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
HERC2 DISC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 90000000 31413325 17043677 33961781
MYC CDK6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22094256 28628118 28205554
MYC HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 22286234 30415952
MYC SMC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 17314511 29467282
MYC PDS5B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21150319 17353931 29467282
SMC3 PDS5A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21111234 17349791 15855230 19906707 26344197 17113138 31010829
PDS5A RAD21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22145905 26496610 15855230 33961781 17112726 17113138 31010829
PDS5A STAG1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15855230 11076961 17113138 31010829
STAG1 PDS5B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17113138 29867216 15855230 26344197 31010829
PDS5B RAD21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22145905 26496610 15855230 33961781 17112726 22293751 17113138 31010829
RAB9A RAE1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 29568061
MBD2 RBBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 33961781 24981860 26186194 11297506
CDCA5 SMC1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 23242214 33961781 26186194 22885700 31010829
SOX2 SMC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 28794006
CDC23 BUB3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 20360068
MAD2L1 BUB1B â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 21772247 8284719
MTA1 CHD3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12431981 24981860 17922035 28977666 9885572 26344197
SOX2 FOXC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 28794006
CDCA5 RAD21 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDCA5 SMC3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDCA5 STAG2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 NFKB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA2 PDS5B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22293751 27924011
EP300 MYB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20364308 11585920 29954426 15691758 35140242 10656693 25740244
MYC PLK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27773673 17314511 33494392 29467282 30415952
CDCA5 PDS5A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21111234 15837422 26496610 31010829
CDCA5 PDS5B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21111234 15837422 26496610 31010829
RBBP7 MTA2 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24981860
NFKB1 SFPQ â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22536447 14743216
SMC3 CDCA5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21111234 28514442 17349791 26496610 15837422 26186194 31010829
CDK4 CDK6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23455922 28205554 28628118 33961781
HDAC1 BUB1B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15388328 19407811
CDC23 BUB1B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20360068 28404789 26496610 33961781 32707033
MTA2 MTA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24981860 21670149 12920132 34026424 26344197
MTA2 CHD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19703393 28977666 10444591 24981860 22939629 11297506 26344197
MDM2 RB1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
BUB3 CDC23 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CDKN1B COPS5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
H2AFX PRKDC â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 SMAD4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CDCA5 SMC1A â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CCND2 CDKN1B â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ATM H2AFX â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CSNK2A1 CSNK2A2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CCNA2 RB1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ANAPC2 MAD2L1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CSNK2A1 HDAC2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
BUB3 MAD2L1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ATM SMC1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11877377 11877376
BUB1B BRCA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28985013 10749118 32286328
CDK7 CDK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 7629134 8647086 11113184 15530371 23064645 25852190 8692842 15282296 16327805 23455922 10393546 16191191
EP300 PAX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 35140242 10506141
SMC1A MCM7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 16438930
MYC CDK4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22094256 28205554 28628118 21988832
PDS5A SMC1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17113138 26496610 15855230 23242214 17112726 26344197 31010829
WAPL PDS5B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20360068 26496610 17112726 17113138 31010829
SMC3 PDS5B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17349791 26496610 15855230 26344197 22293751 17113138 31010829
PDS5B SMC1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17113138 26496610 15855230 23242214 17112726 26344197 31010829
RAD21 PCNA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22145905 22939629 26344197
RB1 RBBP7 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
CHD3 RBBP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 28977666 27705803 33961781 26186194 22939629
STAG2 SMC1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19629043 29867216 26496610 23242214 24981860 17112726 10931856 26344197 29263825 17113138 31010829
WAPL SMC1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20360068 26496610 23242214 17112726 17113138 31010829
WAPL SMC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21111234 20360068 17349791 26496610 17112726 17113138 31010829
SMC3 STAG2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19629043 17962804 17349791 29867216 26496610 15855230 33334891 24981860 18235444 15737063 10931856 22885700 26344197 29263825 17113138 31010829
STAG1 WAPL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20360068 29867216 26496610 17112726 17113138 31010829
CCNA2 PCNA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 12853968 26186194 10930425
CDK4 PCNA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 8259215 11254741 8101826
MECP2 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14647463 12473678 16331260 14593184
HDAC1 CHD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 23752268 9804427 20585571 28977666 27068747 26496610 33961781 17827154 22939629 9885572 11784859
CDC6 CCNA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9566895 9889196 10339564
MBD3 MTA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25123934 26028330 22196727 24981860 21670149 26344197
MBD2 CHD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28977666 24981860 11297506 10444591
CHD3 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28977666 27705803 33961781 24981860 22939629 9885572
CHD3 MBD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 28977666 25123934 24981860
MBD2 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27705803 10471499 33961781 24981860 25753662 11297506
STAG2 WAPL â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 29263825
WAPL STAG2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20360068 29867216 26496610 17112726 25173175 29263825 17113138 31010829
MTA1 MTA2 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
ATM CHEK2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
PKMYT1 PLK1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
NDC80 SMC1A â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CDK6 CDKN1B â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CDK4 CDKN2C â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CTNNB1 FBXW11 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CDC25A CHEK2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
PLK1 BRCA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32286328 14647413 24448238 24835992 28985013 12815053
MYC BRCA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
NFKB1 BRCA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10961992
CHEK1 BRCA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18317453 24627786
CDK2 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 26186194 10330164 23455922
PCNA CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10930425
DISC1 CEP63 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 90000000 31413325 17043677 12812986
CHEK2 TERF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 26799419 19375317
COPS5 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18926707 17879958
MYC DDX11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
EP300 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15154850 20234175 16713569 11070080 9809062 28196907 15013777
EP300 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11268218 16713569 18263614 12937166 24939902 14988403 33742100
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
PCNA MAD2L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
MAPK1 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19941816
MAPK1 ETV3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22028470
MYC MCM7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17353931 17314511 29467282 30415952
MYC MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
HDAC1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15640443 33985974 12426395 30818224
PRKDC MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17570479 22444248 10721693
MEN1 SMAD4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22275377 11274402 15150273
NFKB1 MEN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11526476 16651450 16713569
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MEN1 DBF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16997566 15374998
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
RB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7680889 10200487 9671466
MYC HSPA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
MYC RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC PRKDC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC THRAP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840 12808131
MYC ADCY9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC IRF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC MXD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8649388 10508165 8224841
MYC SMARCAD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
NFKB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2191300 18490439 19219071
MYC CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10899308 17093053
MYC MXI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7565735 17093053
WAPL PDS5A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21111234 20360068 26496610 17112726 17113138 31010829
PDS5A STAG2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17113138 29263825 29867216 15855230 11076961 26344197 31010829
PLK1 PDS5A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
PLK1 PDS5B â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
RNF126 PLK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PLK1 WAPL â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
PLK1 CDCA5 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
STAG1 RAD21 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 17962804 6178082
WAPL RAD21 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22145905 20360068 26496610 33961781 17112726 25173175 17113138 31010829
RAD21 STAG1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22145905 17962804 11590136 29867216 26496610 33961781 17112726 15737063 10931856 22885700 26344197 11076961 21043528 17113138 31010829
RAD21 SMC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15855230 17112726 21111234 17349791 26496610 10931856 21043528 17113138 18235444 22885700 22939629 31010829 21880767 22145905 33961781 24981860 15737063 16802858 20818333 26344197
RAD21 SMC1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 19308699 17112726 31807710 26496610 10931856 21043528 17113138 11590136 22885700 22939629 31010829 22145905 23242214 33961781 24981860 15737063 20818333 26344197
CTCF RAD21 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19369356 19826084
RBBP4 RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17255935 27705803 22863883 33961781 24981860 26186194 15451426 22939629 26344197
MTA2 RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31980649 19703393 22939629 20714342 14645126 10444591 27705803 28179136 33961781 24981860 26186194 12920132 11297506
MBD3 RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25123934 10444591 27705803 33961781 24981860 26186194 22939629
SIRT6 CHD3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
STAG1 SMC1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31807710 29867216 26496610 17112726 10931856 26344197 11076961 17113138 31010829
STAG1 SMC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17962804 17349791 29867216 26496610 15855230 17112726 10931856 22885700 26344197 11076961 17113138 31010829
SMC3 MXD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9528857
SMC3 MXI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9528857
STAG2 STAG1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17962804 29867216 24981860 30021884 11076961 31010829
HDAC1 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11929879 16189514 16713569 14988403
CDK6 CCND2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 28628118 10022865 28205554 11360184 30217970 33961781 23602568 11358847 9178893
CALM3 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2022671 7685187 8417150
FBXW11 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 14988407
SMAD4 CTCF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12099698
MBD2 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 23752268 12665568 10471499 10444591 26496610 21258344 33961781 27173435 24981860 27593931 11102443 17634443 11297506 12183469
MBD3 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10444591 21258344 11102443 12354758 19041848 27068747 26496610 25123934 24048479 21670149 17827154 22939629 23752268 12124384 16428440 33961781 24981860 26344197
MTA1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 27098840 21258344 33264408 9885572 26028330 26496610 14722073 20585571 21670149 22939629 18451879 34026424 23752268 29997244 16511565 26949739 10840944 33961781 11146623 24981860 17922035 12920132 26344197
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
MBD3 HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 20388487 25123934 19041848 26949739 21258344 24981860 17827154 22939629 12354758 26344197
MTA2 HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 31980649 19703393 22939629 30737378 20714342 26949739 10444591 21258344 24981860 12493763 19686092 11102443 12920132 18451879 11297506 26344197
HDAC2 CHD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12198550 23752268 22939629 9804427 30737378 28977666 26949739 24981860 17827154 12493763 9885572
HDAC2 MBD2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 26949739 10471499 10444591 16410616 21258344 24981860 11297506 25753662 12183469 26344197
HDAC2 MTA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 12431981 30737378 26028330 26949739 20651739 21258344 26344197 12493763 11146623 21670149 24981860 9885572 12920132 17671180 18451879 20071335
AURKB KNL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20471944
AURKB HDAC9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22865920
PRKCA CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11463380 17570479 20577053
CREBBP NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12789342 16835236
FLT4 RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12601080
NFKB1 CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24296733 18425349
PRKACA H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11749379 9892015
PRKACA CAMKK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 32913128 10187789 15209507
MYB CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17242210
CAMK2B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24117889
CTNNB1 HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12944908 25241761
ANAPC10 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10318877 10500174
CDC23 ANAPC10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10318877 10500174
MBD3 RBBP4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25123934 10444591 27705803 33961781 24981860 21670149 22939629
MBD3 MBD2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15456747 10444591 15701600 10947852 24981860 11297506
MBD2 MTA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10444591 24981860 11102443 25753662 11297506 26344197
MTA2 MBD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12124384 19703393 25123934 10444591 26344197 24981860 22939629 11297506 12354758
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MAPK1 RPS6KA3 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
DBF4 MCM7 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HDAC2 SMARCA5 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
DBF4 MCM2 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EP300 MYB â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CDC25A FBXW11 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CCND2 CDK2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CDK6 RB1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
MAPK1 RPS6KA2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
E2F2 RB1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
SMC1A SMC2 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
STAG2 SMC1A â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 29263825
MTA1 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 6613464 18451879
PLK1 CCNB1 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 11242082
HDAC1 HDAC9 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
PDS5B STAG1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
MBD3 RBBP7 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CALM3 CAMK2B â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
PDS5A STAG2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CHD3 MTA1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ANAPC1 MAD2L1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
MBD3 RBBP4 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CHD3 HDAC2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
RB1 RBBP4 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
CCNB2 CDK2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CREBBP CTNNB1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CHD3 MTA2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
NDC80 SMC1A â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 23361318 9295362 26344197
CDC6 MCM2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 15232106 23405012
CDK2 CDK7 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
HDAC1 RB1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
BUB1B PLK1 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CDKN1B CDK4 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5219242 17053782
STAG1 SMC3 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 17962804 6178082
CDK2 RB1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CHD3 HDAC1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CDK6 CDKN2C â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
CHD3 RBBP7 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CDK4 RB1 â—¼   PHOSPHORYLATION ✅ - 0.93 0.93 Signor 9139732
MBD3 MTA1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
MBD2 MTA2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CCND2 CDK6 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
MTA2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6613464 18451879
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
CHD3 RBBP4 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CDK2 CDC6 â—¼   PHOSPHORYLATION ✅ - 0.94 0.94 Signor 10339564
CCNA2 CDC6 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
CHEK1 CHEK2 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
BRCA2 PLK1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
ANAPC10 MAD2L1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
STAG2 SMC3 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17962804 6178082
RB1 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 6550000 10779361
CCND2 CDK4 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
RBBP4 SMARCA5 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
MBD3 MTA2 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
CDK2 CDKN1B â—¼   PHOSPHORYLATION ✅ - 0.95 0.95 Signor 17409098
HDAC2 MTA1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
MTA1 RBBP7 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
HDAC1 MTA2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
CTNNB1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 36950384
CCNB1 CDK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 20733051 28514442 9891079 7799941 8397207 25852190 26496610 33961781 26186194 23602568 10995390 23455922 30674583 18471975
CCNB2 CDK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 15232106 28514442 24358021 33961781 26186194 23455922
PCNA CDK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12361598 28514442 26496610 29510343 9545286 33961781 26186194 7903056 21319273 10930425
CDKN1B CCNA2 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 34591612
PDS5A SMC1A â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
PDS5B SMC1A â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
STAG2 RAD21 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17962804 6178082
MTA1 RBBP7 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 27098840 18067919 26028330 27705803 33961781 24981860 26186194 12920132
SF3B3 SF3B1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 21981285 12234937 11406595 28541300 24981860 10490618 22939629 26344197
COPS6 CUL2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
PDS5B RAD21 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
CDK8 POLR2A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
CDC23 MAD2L1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PDS5A RAD21 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
SMC1A STAG2 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ANAPC10 BUB1B â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CDC25A CHEK1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CDC6 CDK2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
HDAC2 MBD2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
MTA2 RBBP4 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
HDAC2 MBD3 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
CDKN1B CDK2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 34591612
MCM7 CDC6 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 23405012 12614612 25990725 10464337 23397142
RAD21 STAG2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 29867216 29263825 17962804 26496610 10931856 21043528 17113138 11590136 12034751 22751501 22885700 31010829 19629043 22145905 33961781 24981860 15737063 25173175 20818333 26344197
HDAC2 RBBP7 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 22939629 20388487 27705803 21258344 33961781 24981860 26186194 15451426 12493763 9885572 26344197
RBBP7 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 19703393 10444591 21258344 11102443 9885572 17255935 10471499 26496610 25885317 22939629 9150135 23752268 9790534 27705803 33961781 26186194 19686092 15451426 12920132 26344197
SMC3 SMC1A â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17112726 21111234 31807710 17349791 26496610 10931856 17113138 18832153 11590136 12759374 30021884 22885700 22939629 9789013 31010829 21880767 11877376 23242214 24981860 27173435 11076961 26344197
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
RBBP4 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 9520398 19703393 31435636 9150133 10444591 21258344 12943729 11102443 9885572 27068747 10471499 26496610 34518534 20127688 11171972 10734134 11470869 20585571 10220385 12091390 17643391 21670149 11602581 17827154 22939629 9150135 23752268 16713569 9790534 27705803 19686092 24981860 33961781 11302704 11118440 15451426 12920132 26344197
HDAC1 MTA2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 31980649 19703393 10444591 21258344 12374985 17956988 11102443 27068747 26496610 20127688 11171972 11297506 20585571 21670149 11602581 22939629 18451879 23752268 9790534 26949739 16645043 22863883 28179136 27173435 24981860 33961781 19686092 12920132 26344197
HDAC1 NFKB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 12972430 17962807 24448807 11931769 14678988 16319923 17827154
HDAC2 RBBP4 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
BUB3 BUB1B â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 25416956 25482201 21988832 25246557 11702782 25852190 25505175 25383541 22000412 26496610 22193957 29973720 25012665 28410192 23791783 21937719 25669885 9660858 12419313 19407811 32707033 11535616 22100920 27939943 24151075 28404789 25833949 32152539 26186194 33961781 20220147
TCF7L2 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 11713475 5214798
MTA1 RBBP4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 16189514 25416956 27144666 27098840 18067919 27705803 33961781 24981860 26186194 21670149 24920672 12920132 33264408 26344197
MTA2 RBBP4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 19703393 22939629 14645126 10444591 27705803 28179136 33961781 24981860 21670149 19686092 11602581 12920132 11297506 26344197
CDC23 FBXO5 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
PDS5A SMC3 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PDS5B SMC3 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
BAZ1A SMARCA5 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
SMC3 STAG2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MBD2 RBBP4 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
HDAC2 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
MBD2 MTA1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
ANAPC2 FBXO5 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
PRPF31 SF3B1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CDK2 CCNA2 â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 10652300
HDAC1 MBD3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CREBBP MYB â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
BUB1B CDC23 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
POLR2A SSU72 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PRPF31 SF3B3 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
MAD2L1 MAD1L1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 6785080 18692475
MAD1L1 MAD2L1 â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 21772247 8284719
MAD2L1 MAD1L1 â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 21772247 8284719
CDK4 PCNA â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
HDAC2 MTA2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
BUB1B BUB3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CCNB1 CDK2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CDK4 CDKN1B â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CCNA2 CDKN1B â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
ANAPC1 BUB1B â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
PRPF6 SF3B1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
EFTUD2 SF3B3 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
CCNA2 CDK2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 8475101 28514442 16431923 33854235 11940657 10559988 15189033 17361108 16290148 14681455 17254966 8662825 25852190 15557281 23455922 19483727 18471975 11141566 10924145 15828833 21241890 19631451 11377199 18177895 8684460 26496610 9716181 12853968 11907280 23602568 9724724 15647383 14656438 19773423 12941338 15239650 24302728 25669885 15890360 7630397 8756328 8397207 21447625 22231403 20733051 9660939 24358021 12044161 33422522 11983168 33961781 26186194 7553852 16209941 12244298 9380407 8463339 15455144 10930425
MCM7 MCM2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16189514 12694531 20808282 8798650 12207017 14681455 9099751 12614612 10748114 23764002 15232106 25963833 30100344 22939629 17296731 10567526 22540012 22863883 33961781 27173435 26186194 16899510 26344197
HDAC2 RBBP4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 31435636 21258344 12943729 9885572 34518534 12493763 12091390 21670149 17827154 22939629 16713569 9804427 20388487 27705803 33961781 24981860 11302704 15451426 26344197
CCND2 CDK4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 16189514 14681455 32296183 9325318 11360184 30217970 28205554 15169570 10022865 17873913 25910212 27107012 28628118 33961781 26186194 11896535 9178893 11971966
EFTUD2 SF3B1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EFTUD2 PRPF31 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
CDC6 MCM7 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CDC6 MCM2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CDK2 PCNA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PRPF6 SF3B3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SF3B3 SNRNP200 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMC1A STAG1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CDK7 POLR2A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MTA2 RBBP7 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HDAC1 MBD2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HDAC1 MTA1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HDAC1 RBBP4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDK4 RB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMC3 STAG1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
MTA1 RBBP4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SF3B1 SNRNP200 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MCM2 MCM7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 SMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 SMC1A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 STAG2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SF3B1 SF3B3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2A SUPT5H â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA1 PSMC2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
BUB1B MAD2L1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5B â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ANAPC1 ANAPC10 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ANAPC1 CDC23 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PRPF31 SNRNP200 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MAD1L1 MAD2L1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CTNNB1 TCF7L2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
ANAPC10 CDC23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CDK2 CDKN1B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC1 ANAPC2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
APC CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
MYC APC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22911891 12695333
PRKACA APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11050185 11166179 15649893 11689703
APC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 10545404 11166179 8259519 7890674 22083140 27902311 8638126 16212417 16798748 19061640 9286858 15327769 9482734 11533658 22056988 19576224 15327768 17318191 26496610 12628243 15355978 9065403 11712088 25241761 26910375 22682247 9065401 12000790 11707392 20219694 9707618 23840886 15525529 11251183 8628279 19631635 11972058 21664290
CDK2 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9781043 16322221 16123081 11292842 10928988
H2AFX ATM â—¼   PHYSICAL_INTERACTION 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
H2AFX ATM â—¼   SHARES_COMPLEX 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
H2AFX ATM â—¼   ENZYMATIC_REACTION ✅ 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM CHEK1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM CHEK2 â—¼   ENZYMATIC_REACTION ✅ 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
ATM SMC3 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM MDM2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
H2AFX ATM â—¼   REGULATES ✅ 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
AURKB ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22099307 27493659
PAXIP1 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15456759 19414588 17690115
ATM TERF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16223874 17525332 15314656
ATM EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20471956 15494392 15140942 29590107 26170237 21108945 15838517 27220480
ATM CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 176.0 1.0 Omnipath 26683224 17303408 28852018 10713094 20080130 27545311 9488723 15342622 23941746 26485758 28937603 15279786 24882580 10744722 15125777 25746763 18583988 28051860 17570479 16531125 21329876 23892398 19607708 16940182 26643553 20396397 28259974 25361978 17660363 15459660 19375317 25247188 16311512 23118481 20498628 22030216 25613496 22420423 9407949 17918214 12493754 20859824 26158765 15700044 27558808 11901158 27602502 20637859 16163361 20599567 23638118 16481012 12242661 23847781 12024051 15140942 11728459 12454775 16936775 25450480 28950914 26295265 20160490 22319212 24349411 18006705 20723763 18678890 12805407 20860841 23386996 24050180 11668173 27271602 29304495 12447382 24798733 9889122 23347679 18794134 21147465 21421565 26516160 17715138 21376743 19440053 12773400 10973490 17174984 26442630 15694385 11877377 29022904 18809224 11850621 18787700 12718885 19481982 22743550 20372057 15212693 16085488 19101576 29555944 25954303 24473398 18087292 16794575 24492479 24244353 19793801 25404613 21102523 29156743 23253087 16997395 7575488 25808488 20647331 18584027 21851590 21315088 23705030 15629715 29741650 21772273 11025670 18590585 26610585 15964794 29434792 20068082 23006513 19881958 19230643 12607003 24769180 25249630 15024084 19772495 25714019 18603484 25173936 23666059 19473886 27568553 22808196
ATM PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17189255 12231622 17303408 24492479 10464290 22230547 15677476 16822724 28985363 29088817 16163361 32868446 19549901 25818648 22923485 19103741 17570479 27939942 19808981 23847781 22355272 24714417 15964794 21376743 31983282 25224041 16908529 12607003 19244120 17525332 15459660 34249431 28107384 12186630 25714019 11877377 26553138 27568553 19535303 15507430 26578593
ATM MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 66.0 1.0 Omnipath 14654783 12383858 17936559 20651945 17303408 19816404 10611322 23150762 23277204 23386996 26416444 27258263 23002429 11331603 15865937 21556066 16163361 23708100 17570479 20514355 22264782 27177180 18265945 28690977 23847781 22264786 15140942 15964794 19788416 22624716 25201202 27462439 12607003 28050229 32350255 22649771 27956626 15459660 22976441 25247188 28904407 11877377 21859827 24534650 23405218 29290977 27568562
ATM SMC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 17303408 14657349 19690332 29988990 26673124 15302935 16163361 20068231 18452278 18077418 17570479 18669648 23847781 15964794 16906133 12607003 9789013 17525332 15459660 11877376 11877377
ATM DBF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17525332 22123827
ATM CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 69.0 1.0 Omnipath 29774099 20976184 26683224 25663895 12676583 17303408 14657349 29167438 27545311 10859164 19056039 15485915 28808226 12588868 16163361 15650047 12676962 17570479 14988723 14681223 26516160 10608806 26069190 29741650 12676925 23847781 17118344 11252893 20376879 15964794 15149599 18691976 19059218 20068082 15707391 12607003 25450480 17525332 11553781 19646247 15870257 15459660 20798862 19716789 11877377 12660173 11390642 15674326 16782033 28396830 28228262 12446774 15533933 15212693 29555944
ATM SMC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 22369641 18442975 15964794 11877377 17303408 16163361 23847781 17570479 12607003 20501661 19906707 17525332 15459660
PCNA BRCA2 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA2 H2AFX â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA2 SFPQ â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
PCNA BRCA2 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA2 H2AFX â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA2 SFPQ â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
PLK1 BRCA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 32286328 12815053
CHEK2 CDC25A â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11438669 15459660 15810020 15867354 17296736 17464182 17568790 18048416 18566216 18756267 18931676 18971944 19686080 19788416 20019063 20126263
CHEK1 CDC25A â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15459660 15798197 17102137 17116885 17296725 17384638 17568790 17582221 18677104 19793801 20126263
CDC25A CDK2 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 1075565 15279786 17303408 17568790 17660363 18073536 18590585 18786381 7575488
MYC CDC25A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8994810 10205150 11154267 9371770 14519204 15677471 17671423
CHEK2 CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 52.0 1.0 Omnipath 18566216 12676583 15810020 18285803 12759351 14681206 20860841 16682204 9836640 10724175 29725502 23855452 20126263 18480045 11298456 20587702 15459660 20514219 22263797 27038604 17464182 14559997 12399544 17568790 24882577 19101576
CHEK1 CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 75.0 1.0 Omnipath 12676583 22040655 29435105 12759351 14681206 18677104 20860841 15798197 19793801 22655267 12963847 16682204 14752276 16647857 15736430 29725502 17116885 17582221 20126263 16697662 18167338 19075565 9278511 18480045 17384638 21148633 21252624 27493659 12110582 17030123 23335075 20068082 11298456 27908669 27213455 25936524 15459660 28150240 20798862 22263797 27038604 17296725 14559997 12399544 17102137 17568790 16488126
MYC CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8425218 15121849 11602341 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
CDC25A CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 7575488 18590585 17303408 18073536 1075565 17568790 23429262 18786381 17660363 15279786
CDC25A CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 8617791 11602341 17303408 18073536 1075565 15279786 7575488 10454565 11154267 12411508 16189514 1396589 18590585 18786381 17660363 12388094 22263797 27485204 17568790 15659558
CDC25A CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7575488 18590585 11585757 17303408 10454565 18073536 1075565 17568790 23429262 18786381 17660363 15279786
CCNA2 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
MYC CDK2 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
MYC CDK2 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
CDK7 CDK2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11900249 12648680 15703371 16697054 17386261 17884153 19667075 19809470 19847258 7533895
RB1 CDK2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10323868 10375532 16582612 12730199
CDK2 RB1 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 12086603 14536078 14988723 15136767 15147722 15175241 15279786 15798197 16713580 16805667 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18469862 18590585 18636226 18995830 19282663 19342888 19622404 19793801 20051983 7575488
CDK2 MCM2 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 MCM7 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 CDC6 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK7 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 18767875 11113184 25271736 7880532 19690332 19667075 15703371 14597612 20360007 21565702 19809470 15302935 8443411 7533895 10085115 15671017 17095507 10886368 17386261 20068231 18452278 9244189 8069918 11840777 1396589 17570665 16325401 16327805 25788262 11959850 15530371 11532001 19056339 9130709 14551212 17192257 19847258 22505032 17884153 20147522 12648680 11900249 16697054 93010995 8393783
MAPK1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10962581 12359725
CDK2 SF3B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15212693 12105215 17081983 30115685
CDK2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8386367 27653698 17081983 19966300 18669648 29896817 17570479 20713526 17558397 15103331 22348395 20445224
CDK2 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 77.0 1.0 Omnipath 26581405 9315635 17303408 18692063 23437375 19413330 20871633 26148348 28806746 15279786 16326706 8626527 21902831 14627988 7575488 9190208 21697511 9139732 20068231 17570479 16189514 12006580 11420722 18669648 15811853 18590585 27507850 17380128 23160093 19638577 1756735 20418918 19262748 17660363 11777937 10499802 19651622 20058876 15173007 22263797 10207050 8756624 10542199 19664994 24466208
CDK2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 81.0 1.0 Omnipath 8756328 7553852 11377199 17145710 23602568 11983168 12044161 19483727 12853968 16209941 8397207 15455144 19631451 8475101 24358021 15557281 8684460 12941338 15647383 15890360 21447625 9380407 26496610 11141566 25852190 15189033 14656438 20733051 21241890 10652300 25669885 12244298 26186194 10930425 9660939 10477583 24302728 15239650 19773423 8463339 16290148 10924145 11907280 17361108 17254966 8662825 15828833 18471975 9724724 7630397 10559988 9716181 11940657 23455922
CDK2 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 125.0 1.0 Omnipath 26416244 20519948 19631451 16326706 17409098 15557281 9658399 23029392 22733130 17570479 26496610 23576547 12700233 9388487 10585280 27282251 27175940 15619620 25241761 15735731 9218599 9192873 17254966 15996662 9724724 11940657 18285702 22492278 23409140 18615582 12093740 22721951 15647383 9380407 17418410 16189514 17053782 17698606 25852190 10679394 17602833 9660939 12188931 15122251 10831586 25818643 22028818 21424700 12529437 15011833 12042314 11250701 11223033 23455922 8978686 16780593 21439954 15302935 19648963 14504289 9736735 10198259 16782892 11565035 21423803 16492801 9311993 12417722 17671428 21187893 15355997 28601655 10809788 10393546 15212693 10323868 26450989 23602568 18850315 12482975 9399644 15890360 9632134 17254967 26186194 20810788 20197382 15475007 12800980 17997402 12972555 15980415 24336329 26701207 25605247 26987798
CDK2 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21765472 21965652 21907702 18983824 24242917
CDK2 CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 42.0 1.0 Omnipath 17303408 23129444 19793801 15279786 7575488 20068231 17116885 17582221 17570479 9889196 27207654 16153703 18590585 29760377 18691976 10339564 14749377 19343071 17660363 16707497 17296725 24216307 23479742 17102137 15212693
CDK2 MCM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7575488 18590585 17296725 17303408 16899510 17102137 17116885 19793801 17582221 16446360 17570479 26549452 17660363 15279786
CDKN1B CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CCND2 CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CDK4 CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CDK7 CDK6 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CDK7 MCM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 26593718 31067464 30940728 16899510 16864800 23993743 16446360 15210935 24901225 31776133
CDK7 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 7533895 14597415 19847258 8139570 12814430 17386261 16327805 16782892 28368408 17884153 19667075 15703371 14754892 12648680 11900249 12459251 16697054 19809470
CDK7 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18079403 27197304 26799765 10886368 14662762 16327805 24662513 26748711 25561469 21331744 19667075 18079404 22137580 9130709 20457598 19901026 19450536 20932174
RB1 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
FLT3 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10323868 17254966 28522571 19075005
MAPK1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12042314 9192873 10831586 10931950 12700233 15212693 15735731
CDK6 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16160006 25241761 18615582 16782892 21439954 11360184
COPS5 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 17145710 22350412 15688030 18926707 24671224 12082530 18202760
CDKN1B CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25910212 16189514
CDKN1B CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 23602568 8978686 23707388 21439954 18850315 16326706 9658399 14597415 18615582 10198259 16782892 9632134 16189514 17053782 11360184 9311993 17092340 20837141 26186194 25241761 15695403 9464540 19470470 9106657 10908655 23543736 11940657 18285702
CDKN1B CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17145710 8684460 26186194 9660939 17254966 15890360 16209941 12947099 12501191 26496610 9724724 9311993 9716181
PCNA CHEK1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
CHEK1 CDC6 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 MCM2 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 MCM7 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
PCNA CHEK1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
CHEK1 CDC6 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 MCM7 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 MCM2 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 MCM2 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 CDC6 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 MCM7 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK2 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26516160 24804719 26437226 29555944
CHEK1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17380128
CHEK1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 18451105 20068082 23844048 12560483 18066052 20948546 21357687 18243098
CHEK1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23321637 22024163 17276342
CHEK1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22152481 23180782
H2AFX CHEK2 â—¼   ENZYMATIC_REACTION ✅ 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
PLK1 CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 12024051 24844881 18802408 19216791 10973490 18804494 12242661 20126263 16189514 11901158 12493754
PRKDC CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 77.0 1.0 Omnipath 31959038 12607004 22669845 18948271 16794575 24492479 15829965 23684611 12805407 20406977 26929199 21482692 27818175 20660628 33870196 11668173 21731742 33879618 15618221 11901158 24421316 21099343 12386164 15096610 24415760 12447382 12855706 15213307 16150728 20599567 16024600 17570479 12447371 28750002 34244606 33901880 15367709 26505995 16940182 33747205 11025670 12024051 24844881 15668230 10973490 20713355 33961649 19151762 16936775 16798742 12607003 30001349 18644861 25361978 20305300 11390408 20501833 15361851 16982735 23380594 15674326 17237275 20160490 20498628 33851958 15282313 25550082 31609975 15975956 11085506 12493754
CHEK2 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15862297 10710310
CHEK2 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24466208 17380128
COPS5 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11818334 27060206 16713569 17583730 14993265 1818334 24078030
CSNK2A2 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17570479 17287340 19413330 18669648
CSNK2A2 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19651622 19415658 12082111 16565220 19007248 19691289 18669648 20166139 18691976 17081983 20230923 20068231 18452278 17570479 17287340 19413330 18510355 18212344
CSNK2A2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12700239 19141652 12432063
CSNK2A2 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 26186194 27705803 25519132 19011756 26496610 25852190 23455922
CSNK2A2 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11711551 18452278
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
EP300 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9843571 19419955 22033265 9679056 21269274
EP300 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19608861 29954426 18585056 15691758 10656693 25740244
EP300 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
FBXW11 FBXO5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19847258 19686080 19270156 17884153 19622404 15703371 12648680 11900249 16697054 18931676 19809470 15459660
CCNB1 FBXO5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17660363 15279786 15917306
PLK1 FBXO5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17145710 18931676 19270156 19622404 17875940 16439210 15148369 19686080 15469984
HERC2 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
MEN1 IQGAP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
PRKCA IQGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 27815503 21349850 25618329 15695813 25733387 28739799 15355962 31474712
CALM3 IQGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9182573 12446675 11809768 11734550 12377780 8670801 10608854
IQGAP1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15655247 11319218 8226933 1330321 1497021909368021 16135787 17563371 7992057 8248196
IQGAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12446675 9694656 11734550 12377780 16622255 10473551
FGFR3 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
MYC MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22789855 21933022 16596619 23617883 8013639 20144848
PRKCA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
MAPK1 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8939914 12832467 9915826 17906627 32296183 19282669
MAPK1 RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21988832 18156174 12016217 25241761 12832467 23602568 8939914 10480933 9915826 17906627 10980595 10856237 19282669
MAPK1 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12721286 15212693 14517250 14662762
MAPK1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12801888
MAPK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10551811 17081983 8386367 17251036 91332050 17570479 1748630 7957875 27167001 15212693 1651323 15210690
MCM7 CDC6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 CDC6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
DBF4 MCM7 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
DBF4 MCM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7575488 18590585 17296725 17303408 12614612 10846177 17018296 17102137 17116885 17582221 19793801 16189514 17660363 15279786
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
PLK1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12383858 19833129 23948487 24265276 26754547
MDM2 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16374512 21990374 7791904 28615518 33185004 20871633 10078201
MEN1 CTNNB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
MEN1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11526476 16997566 16713569
PLK1 MYC â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
KLF8 MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
NFKB1 MYC â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18490439 19219071 21725609 2191300 23178297 23572150
CTCF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10625678 8649389 2284094 12032779 19568426 24725430 12524457 8246978 12897849 9591631 1795697
NFKB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 12504005 19469019 21790895 19766095 17018379 8289784 18566231 1515224
TCF7L2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 12095419 19561604 19895682 15579438 26947016 16204248 12799378 12907606 17360646 9727977 21533051 20133699 15576399 19784072 24447505 12591729 20818421 18852287 11973610
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
SMAD4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11689553 17132729
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
MYC CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8386381 10713672 12835716 7608142 12937171 14519204 14729654
MYC PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7597041 18358094 22911891 18809243 1280813111085504 11085504
MYC CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7526316 11511535 10508165 9339900 15988028 20857481 11060032 14519204 14660677 10956386 21790895 11264343
MYC CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12747840 11522645 11983916 19470724
MYC CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15208653 12835716 24951594 21384303 14519204 22395148 10688915 17728244 11983916 18414489
MYC CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20682794 22395148 12835716
CREBBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17303408 15522869 12776737 20144767 17660363 16878156 15279786
PLK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 19270156 25915540 23887393 19622404 19686080
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
TCF7L2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
MTA1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
MYC CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8425218 15121849 11602341 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
MYC CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 11602341 17093053 22094256
PLK1 GOLGA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12839990 20937827 15678101 11447294
PLK1 PKMYT1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
PLK1 RAD21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15737063 25299182 18931676 18616427 11073952 19270156 19622404 19686080
PLK1 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19686080 19270156 18931676 19622404
PLK1 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18931676 16565220 19270156 19622404 27120157 19686080 14657031 15302935
PLK1 CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21041660
PLK1 PKMYT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 18931676 18691976 19270156 26899266 12738781 19622404 27603133 26597303 19686080
PLK1 STAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19686080 19270156 18931676 19622404
PLK1 STAG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 18616427 19270156 19622404 19686080
PLK1 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 19270156 19622404 19686080 14657031
PLK1 BUB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 23695676 19228686 17376779 27568981 23079597 26259146 27308323 17785528 19015317 22566210
PLK1 ANAPC10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19686080 19270156 18931676 19622404
PLK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20404109 16854412 26899266 19364923 25362646 20126263 12524548 26729093 11242082 12447691
PRKDC HNRNPU â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27303920 25986610 19351595 25030905 19844162
RAD21 STAG1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
STAG2 RAD21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 28430577 12034751 11590136 25173175 22885700 29263825
WAPL RAD21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17145710 17112726
CTCF RBBP7 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17851529 17761849 25135475 17185360
SIRT6 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18337721 16439206 19408108
SMC1A SMC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
BUB3 SMC3 â—¼   UP_REGULATES ✅ 21.0 1.0 ACSN 10477750 11402067 11535616 12640463 15024386 15279786 15592459 17303408 17376779 17498870 17660363 18022367 18590585 19154723 19182530 19503101 21270334 23197039 7575488 8824189 9790499
HDAC1 TNF â—¼   DOWN_REGULATES ✅ - 15.0 1.0 ACSN 10754326 10952726 11875494 12907458 14660645 14668329 15465827 15644117 16878026 17404308 17485448 21234400 22796940 23390297 7594497
NFKB1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17513725 12058956 24337575 12657243 17704137 12471036 17707233 7624137 11259437 12686724 16433741 26114754 20237317 7876168 16707469 12117498 14976218 10485496 15465827 8622636 15812247 21138578 18990758 10748079 15013838 15749903 16916598 17646159 10754326 16040075 10837498 18285351 11675405 11739517 15743782 20066113 20617556 17085785 8530146 8805669 10919279 14960579 1740105 10963848 16055086 9742085 17292554 10553096 11312646 15543947 17442180 16285952 10079106 11297551 10551799 10201927 12907458 8679226 9281604 22782967 8219230 11749970 9916895 11094063 11490006 7895918 1618817 16483936 18057724 20722069 16569682 9452482 17407192 17082635
PCNA H2AFX â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA H2AFX â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
E2F2 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15510213 18319725 11491305
RB1 CDK6 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
CDKN2C CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 25910212 8840966 26186194 17353931 27107012 23602568 25416956 25502805 8891723 12370184 31515488 11124804 18394558 32296183 16713569 16915296 8001816
CCND2 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10477583 17517622 16713569
CDK6 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 43.0 1.0 Omnipath 10498883 9315635 17303408 11416152 15081408 16236519 19690332 16936279 11520855 16107892 19413330 15279786 16360038 9190208 14627988 7575488 24417566 8822197 10385618 9736735 9139732 7736585 19075565 29372101 18590585 27507850 22682621 20068082 9425340 25549286 18786381 17660363 15809340 27811360 10778858 9380698
CDK6 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17208333
CDKN2C CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 25910212 21988832 11900540 23455922 17353931 26186194 27107012 23602568 25416956 8891723 31515488 32296183 16915296 8001816
AURKB NDC80 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23569217 20471944 14602875
NFKB1 BECN1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 19289499 21725609 23178297 23572150
TGFBR2 SMAD4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 14557817 15265520 16474430 17934056 20060931 20519943 21614932 22703233 24132110 24336330
TGFBR2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8774881 20060931 11274345 21614932
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 TCF7L2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
CSNK2A1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17287340 19413330 22113938 18669648
MECOM HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11552981 23858473 16713569 11568182
CSNK2A1 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 19007248 16565220 20166139 17081983 20230923 25609639 19413330 19415658 20388487 20068231 18452278 18669648 18691976 17287340 12176973 19651622 12082111 19691289 24526703 18510355 18212344
AURKB BUB3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 27496133 27933271 19225156
AURKB H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11278789 19007248 17938195 10464286 16457588 12234980 12082625 21282660 15249581 10949293 15108802 16185088 14583461 12588998 15681610 17924679 16222246 15684425 12560483 11856369
AURKB HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22865920
MCM2 CDC6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 CDC6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
DBF4 CDC6 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
CCNA2 CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9889196 10339564 9566895
DBF4 MCM2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
DBF4 MCM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 7575488 18590585 17296725 18286467 17303408 12614612 10846177 17018296 17102137 17116885 17582221 19793801 16189514 26167883 17660363 15279786
CSNK2A1 MCM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 19864417 22179839 24240236 18286467 27407105 16899510 16864800 25412417 19647517 31578521 16446360 24902048 26921250 28273463 17062569 25843623 29959228
CTNNB1 CREBBP â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
CREBBP TCF7L2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
CREBBP CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10769018 21751375 11973335 17410209 18347063 16476742 23273993
CREBBP MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8654374 11073948 12196545 16055500 18585056 16799563 23980173 14761981
PRKACA NFKB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
PRKACA NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19531803 12947093 17959673 15642694 15197457
RB1 CDK4 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
CCND2 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 25910212 17517622 27107012 11896535 10477583 9325318 31515488 16189514 32296183
CDK4 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 107.0 1.0 Omnipath 26203195 10498883 23336272 9315635 17303408 17363486 25803170 10359571 15081408 16236519 28249908 16936279 17478427 19690332 11520855 31615938 15279786 16326706 18981099 9190208 8626527 14627988 7575488 24417566 9003781 16360038 10385618 9736735 9139732 7736585 20068231 34158578 16189514 19075565 18669648 11773438 11641415 21880723 18590585 27708221 10962560 20068082 15489884 9425340 19225156 19551155 17045206 10210318 19262748 18786381 17660363 17621266 19651622 12657252 11746527 11254678 15809340 22263797 10202152 10778858 27811360 23981302 19664994 14676836 9380698 18583321 23429262 27430527
PKMYT1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 9001210 12814430 10373560 18319725 12738781 26496610 23397142 10504341
FLT3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17496910 22558232 17851558 12040186 19568798 22126602 14585353
RAB11A RPGRIP1L â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 17574030 20399632 23253480 17646400 21273506
BET1 GOLGA2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 9094723 9647643 24119662 10747087 23378591 16303754 19164740 9307973 25406594 17038314 8663406
CCNB1 GOLGA2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 15678101 7737117 11238451 11306556 18167358 1902553 9150144 10679020 9753325 11285137
CCNB2 GOLGA2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 15678101 7737117 11238451 11306556 18167358 1902553 9150144 10679020 9753325 11285137
PRKACA HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22865920 20716686
KNL1 BUB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21199919 20220147 17981135 25852190 22000412
PRKACA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 33914026 16199882 22173096 21303971 33815677 22094462 17287208 26068882 26884171 33605402 21506126 24117889 12297048 21822311 16476742
PRKACA HDAC8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15242608 14701748 31633931 16809764
RB1 CCND2 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
CTNNB1 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
TCF7L2 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
CCND2 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 10498883 9315635 17303408 16236519 11520855 15279786 16326706 9190208 7575488 9003781 10385618 9736735 7736585 19075565 18590585 20068082 9425340 8449399 18786381 17660363 19651622 11254678 8343202 10778858
CDC23 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17660363 16123593 15279786 15917306
E2F2 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15510213 18319725
ANAPC1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17660363 16123593 15279786 15917306
ANAPC10 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17660363 16123593 15279786 15917306
ANAPC2 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17660363 16123593 15279786 15917306
CSNK2A1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12700239 12432063
CSNK2A1 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11522824 7735324 11313925
CSNK2A1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11711551 18452278
TCF7L2 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24214913 14706452 19347947 24317174
FBXW11 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23331499 9784611 22682247 10074433
CTNNB1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 17145710 9488439 11713475 12446687 17143293 27902311 16569639 22014570 16724116 11955446 16442529 26350900 19202075 17050667 20126258 22056988 16306047 17914096 19443654 18391971 21670201 22155184 10080941 17283121 16230076 22304967 16630820 15684397 11713476 12861022 19304756 20492721 19816403 18772112
ANAPC10 ANAPC2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ANAPC2 CDC23 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
EFTUD2 PRPF6 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
EFTUD2 SNRNP200 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
PRPF31 PRPF6 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
PRPF6 SNRNP200 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SSU72 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15125841 20861839
MAD1L1 MAD2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 31467278 32814053 16713569 10660610 21988832 21772247 16189514 26258632 26496610 21525009 25012665 21041666 11459826 11707408 18692475 32296183 15694304 24581499 26986935 29997244 18318601 31515488 22493223
CTCF RBBP4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17851529 17761849 25135475 17185360
RB1 E2F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 16360038 17380128 12502741 8657117 17488475 8246996 16189514 22569856 7739537 8832394
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870
RPS6KA3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15994958 10464286 10436156 14625384