Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SQSTM1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MAP1LC3A SQSTM1 â—¼   COLOCALIZATION 2.0 0.8 intact 19427866 7034152
HSPA5 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
LCK CCDC50 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19059208
HSPA5 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TNFAIP3 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19131965 20599425
UBC TNFAIP3 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
RPS3A CCDC50 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
OTUD7B UBB â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
UBC SQSTM1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5216530 12857745
EGFR LIMA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24797263 31980649
EGFR IGF1R â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
TNFAIP3 UBB â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
ESR1 IGF1R â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10749889 24051437 14764897 28555617 16113100
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ESR1 MYH9 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21182205 19805454 25604459
MAVS TMEM173 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ARRDC3 TNFAIP3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
IFIH1 MAVS â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 28065597 20935677 11887937 17284441
MAVS IFIH1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22623778 16127453 19881509 19416887 32612200 22301138 17600090 33372174 33649232 30193849 27312109 21903422
HSPA5 SQSTM1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
RIPK1 FADD â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11854271 23972990 24098568 33469115 11002422 26733177 19524513 26865630 32296183 22864571 27560715 23744296 32024820 21183682 30561431 21052097 19373245 24577083 21458669 21737329 32707033 21525013 22848449 29497034 33961781 26186194 26972597 21620750
RIPK1 TNFAIP3 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MAVS DDX58 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22114345 20007272 32612200 31433974 20071582 22022264 19164550 30193849 30267576 21903422 33649232 20554965 16153868 20080758 21102435 21292167 29053956 26494172 26061460 33372174 28594325 21844353 30558248 16127453 18200010 16177806 22301138 17190814 29263274 24478431 20434986 22623778 16585524 19193793 34544279 17709747 19454348 20406818 33976430
DDX58 UBC â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
DDX58 TANK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19668221 19479062 17327220
MAVS TANK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19668221 19479062 17327220
TANK IFIH1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19668221 19479062 17327220
SQSTM1 UBC â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
MAP1LC3B SQSTM1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
MAP1LC3A SQSTM1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
SQSTM1 MAP1LC3A â—¼   COLOCALIZATION ✅ 0.95 0.95 mint 19427866 7034152
OTUD7B UBC â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
TNFAIP3 UBC â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
DDX58 MAVS â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
FADD RIPK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
RIPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11116146
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
EGFR CCDC50 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19059208 15951569
SQSTM1 FADD â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 12702723 15340068 16252010 16498403 20531300 21981924 23069999 25002027 26587781 28574505 9184224
SQSTM1 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 12702723 15340068 16252010 16498403 20531300 21981924 23069999 25002027 26587781 28574505 9184224
MAP1LC3A SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 20061800 23022382 23459205 35044719 22963397 36036324 31053714 21045561 25921531 19250911 17580304 21628531 20204693 28740232 23640897 25686248 24100292 26075355 20562859 22658522 25984893 21460636 16286508 19427866 32296183 23989536 19021777 26268733 22714671 24998849 18653543 31366950 33436498 16169070 23239879 26754771
MAP1LC3B SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 18083104 23022382 35044719 26413874 25416956 22434781 31053714 24023838 19250911 17580304 23333919 20452972 24668264 28085563 21900206 20562859 20010802 25007327 32296183 33302793 24582747 33436498 16169070
SQSTM1 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26416459 10356400 19850933
RIPK1 FADD â—¼   PHYSICAL_INTERACTION 90.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 14744430 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18545270 18633355 18641653 19392652 19411070 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22421439 22427918 22955274 23010170 23069999 23073834 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24366341 24378531 24699077 24958845 26024392 26201938 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 8910423 9184224 9217161 9488730 9759866
RIPK1 FADD â—¼   SHARES_COMPLEX 90.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 14744430 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18545270 18633355 18641653 19392652 19411070 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22421439 22427918 22955274 23010170 23069999 23073834 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24366341 24378531 24699077 24958845 26024392 26201938 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 8910423 9184224 9217161 9488730 9759866
FADD RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 16585540 22864571 26733177 11002422 11854271 19524512 21458669 21525013 21052097 26865630 21741934 23972990 21620750 26186194 27560715 24098568 20203691 16227629 32296183 18485876 32024820 22890322 11464215 21737329 12887920 21183682 19524513 26972597 19373245 22848449 24577083
LCK ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9500442 10571988 25386784 11145737 7539106 27748765
TNFAIP3 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 20448643 17703191 18246070 15258597 19131965
ESR1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17170218 20021813 16087727 19250214 10982795 24281069 18414489 15595626
DDX58 MAVS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 61.0 1.0 Omnipath 17145710 20554965 16127453 33372174 20007272 35075101 21419663 16585524 20406818 19052324 17020950 21903422 19164550 24478431 17190814 16713980 18200010 18948594 19193793 16177806 34544279 16153868 23843640 16785313 16301520 21844353 16125763 19036819 18977754 21102435 33976430 22301138 17709747 21200404 29263274 26494172 23499489 18207245 19881509 22844514 20080758
IFIH1 MAVS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19416887 22301138 17600090 17020950 19052324 21903422 16410796 16785313 16713980 23499489 16127453 33372174 16125763