Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GRB2 ACTN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
PDLIM1 ACTN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
YWHAZ ACTN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
GRB2 ACTR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
ACTC1 DBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GRB2 DBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
DOT1L CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000539 21103407
YWHAZ EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217069 15225635
SH3BGRL EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16729043 5218694
EGFR NUMBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
STAT1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10558875 22693070
EGFR YWHAZ â—¼   COLOCALIZATION 2.0 0.8 intact 5217069 15225635
MFHAS1 GAK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
AKAP2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
LYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
GRB2 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SPTAN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 NEXN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 IPO7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 LUZP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 LIMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 IQGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ACTC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TNFAIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 PPP1CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SVIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 FLNB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ARPC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CORO1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 EPS15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 CFL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 DAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 ABLIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RAI14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 MYH9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ANXA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ITPR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SYNPO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPP1R9B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CORO1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CAMK2D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PLEC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 MYO1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 DAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TMOD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 FLNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SPTBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
FGFR1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9480847 16713569
IPO7 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ IQGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
MAPK1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
MAPK1 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
FOS MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7588633 12134156
PPP1CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
MAPK1 LIMA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23188829
AP2B1 MKI67 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CDC42 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
PLEC PPP1R15A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PPP1R9B PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
YWHAB RAI14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
ACTB WDR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CAV1 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17502619 0611416104
ARPC3 ARPC1B â—¼   PROXIMITY 2.0 0.8 intact 20404198 0911668107
FLNA YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
STAT1 CAMK2D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
STAT1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19061877
DAPK1 LIMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
CTNNB1 CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
CDH1 LIMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0710504105 18093941
CTBP1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21681822
CDH1 ARPC1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11882288
KSR1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9115393 9858547
HSPA5 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAB SPTAN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8009988 20598904
FOS RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10085083 15068801
ARHGAP21 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15793564 32203420
YWHAZ LGALS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
ESR2 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12138116 16423895
MFHAS1 FGFR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
TNFAIP1 FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FOS HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11719466 10472808
FOS PDHA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8476854
CFTR CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12208510 5215704
SORBS2 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CTNNB1 CTNNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
YWHAZ ARHGAP21 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
SPTAN1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CFL1 ACTC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ACTC1 PLEC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CTNNA1 LIMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0710504105 18093941
YWHAZ CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215799 12361576
CFL2 CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PRPF8 ANXA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PRPF8 LIMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAZ ANXA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
ANXA2 AHNAK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AHNAK YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
LIMA1 IK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MFHAS1 LIMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ACTBL2 LIMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAZ LIMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
SORBS2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
SPTBN1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
VCL YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
EGFR JUP â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
PPP1CA TPRN â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
CAV1 RHOA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31871319 20460433 9647788
CADH1 FGFR1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11401320 25241761 27371729
CFTR YWHAB â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
CFTR YWHAZ â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
ANLN ACTN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
DOK2 EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10508618
EGFR LIMA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24797263 31980649
EGFR ACTB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22366308 31980649
CFTR IPO7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
TMOD3 MYO5B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LRC39 MYO5B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
ANLN MYO5B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN NEXN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
LIMA1 NEXN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26496610
SOX2 PAK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PPP1R15A PPP1CA â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5217094 15231748
ZFP41 RAI14 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
ANLN RAI14 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
PP1G RAI14 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30344098 26496610
ANLN TWF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN WDR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
SVIL ACTB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 12202484
ANLN ARPC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN MYH9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
MYH9 PP1G â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30344098 26496610
ANLN FLNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
FLNA TES â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28378594 26496610
ANLN AP2B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
DAB2 AP2B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22323290 34079125
AP2B1 FCHO2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
AP2B1 STON2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
AP2B1 BMP2K â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
ANLN MYO1E â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
KSR1 LIMA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27086506 27173435
RHOA RAP2C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LIMA1 CDC42 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31980649 26496610
CDC42 RAB1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
CFTR CAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
BMI1 PLEC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 LIMA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
CFTR AIFM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
CFTR DAB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20351096 17110338
CFTR CADH1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
CADH1 ANLN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25468996
ACTC ANLN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30890647 31586073
ANLN LUZP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN AFAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN SYNPO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN PLEC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN BASP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN TMOD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN SVIL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN DREB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN FLNB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN SEPT9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN MYO5A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN TMOD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN LIMA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN ITPR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN TPRN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN MYO1C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
TMOD3 MYO5A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DREB MYO5A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
PKHA7 FLOT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 28877994
ARRB2 FLNB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FLNB BTF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19293945 33644029
COBL ACTC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TMOD3 COBL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LIMA1 CADH1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25468996 18093941
LIMA1 PP1G â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30344098 26496610
DREB PP1G â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30344098 26496610
SYNPO PP1G â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30344098 26496610
PP1G SVIL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30344098 26496610
TES FLNB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19293945 28378594
TMOD3 SVIL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LIMA1 TES â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28378594 26496610
MYO1C TMOD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
GSTK1 LIMA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TMOD3 TWF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DEN1A PKHA7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27173435 28877994
PKHA7 LIMA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27173435 28877994
LIMA1 DEN1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27173435 26496610
LIMA1 DREB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
DREB TMOD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
LRCH3 TMOD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ACTB SVIL â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
FER EGFR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 7623846 18271526
EGFR ANXA2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25136068 26320552
GAK HIP1R â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
ANLN LYN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 31586073 26496610
HDAC6 MCM7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 23703321
TMOD1 MYO5B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TWF1 ACTC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30890647 12207032
PP1G ACTB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21382349 17683050 30344098
MYH9 ACTB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22366308 16186248 26496610
ACTB CAV1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17502619 28734243
HDAC6 CFTR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31501480 22069321 14675537
ANLN MYO5C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 31586073 26496610
TWF2 ACTC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 30890647
LRC39 LIMA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ZFP41 LIMA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TMOD1 MYO5C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 26496610
MYO5C TMOD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
PPP1CC TPRN â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CDC42 RAP1A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
GRB2 DREB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12577067 25814554
MYO1C TWF1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
DAPK1 TWF1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 25852190
DREB TWF1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
LIMA1 TWF1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
ESR2 ACTB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 21951318
FLNA ARRB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16611986 17620599
DAPK1 SVIL â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 25852190
DAPK1 TMOD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 25852190
CDC42 TMOD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31478661 31980649
CFTR FLOT2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 29924966 17110338
CFTR SVIL â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 29924966 17110338
FLOT1 SVIL â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
STON2 EPS15 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 6179743 18200045
EPS15 STON2 â—¼   COLOCALIZATION ✅ 0.84 0.84 mint 6179743 18200045
CTNNB1 IQGAP1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ACTN4 VCL â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
PPP1CA PPP1R3C â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
PPP1CC PPP1R3C â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
UBXN2A UBXN6 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
EGFR AP2B1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24797263 24189400 7534311 23956138
GRB2 FLNA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17474147 12577067 21706016
CFTR MYH9 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22038833 29924966 26618866
DAB2 FCHO2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22323290 27237791 28514442 33961781
CFTR LIMA1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
CFTR TMOD3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
AFAP1 ACTC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 12134071
IK PRPF8 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
DSG2 JUP â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
LIMA1 ACTB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
MYO1E MYH9 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26344197 26496610
FLNA MYH9 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22939629 26496610
ESR2 MYH9 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25604459 21951318
DREB FLNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22939629 26496610
SVIL FLNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20309963 26496610
RAB5C CAV1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
RAB5C FLOT2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
FLOT1 RAB5C â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22939629 26496610
ESR2 PLEC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25604459 21951318
FLNB SYNPO â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19293945 26496610
SVIL LIMA1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20309963 26496610
LIMA1 ACTC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 30890647 26496610
ACTC DREB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 30890647 30021884
ACTB CAPZA1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
EGFR ARRB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
NEXN ACTB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125
DREB ACTB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125
COBL ACTB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125
TMOD3 ACTB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125
EPS15 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 19380743
ANLN RHOA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31871319 25959226
RAB5C SUN2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 17353931 33961781 26496610
TPRN PP1G â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 27880917 30344098 23080069 33961781 26186194 21382349 24366813
TMOD3 ACTC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 30890647
KCTD10 TNFAIP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EGFR YWHAZ â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EGFR STAT1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
AP2B1 ARRB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ACTB CFL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
FLNA FLNB â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EPS15 GRB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17474147 19109251 7797522
DAB2 GRB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 11371563 16713569 17474147 9569023 10542228 20936779 22323290
GRB2 MYH9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12577067 20936779 24189400
PPP1CB PPP1R18 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CFL2 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8153045 21516116
TWF2 ACTB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
MYH9 ACTC â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 30890647 26496610
FLNA ARRB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17984062 16611986 17620599
RAP1B CDC42 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 26344197
YWHAE YWHAH â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
RAB5C RAB1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 26344197
EPS15 FCHO2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21762413 19380743 27237791
PKHA7 CADH1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25468996 28877994 19041755
CAV1 EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PPP1CA PPP1CB â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EGFR EPS15 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CTNNB1 JUP â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAB YWHAE â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
COBL PACSIN3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAB YWHAH â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAH YWHAZ â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
PPP1CB PPP1CC â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
YWHAB YWHAZ â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CDH1 CTNNA1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
EGFR ACTN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649 26320552
EGFR PAK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31980649 24658140 12522133 25402006
EGFR ARRB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
ANXA2 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 31980649 12577067 7510700 9565634 19380743
CAV1 FLOT2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 10212252 16189514
FLOT1 FLOT2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17113085 30021884 34079125 22939629 24167781 24809731
ACTR2 CORO1C â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
PPP1CB PPP1R3C â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
EGFR RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
CADH1 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 31980649 24189400 24658140 25402006 25468996 10969083
EGFR HDAC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 24658140 20133936 25402006
EGFR STAT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24797263 31980649 23956138 11294897 15322115 24658140 12637327 7690989 15284024 10918587 25402006 7543024 12070153 12817007 10358079 7657660 11839738
EGFR CAV1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16407214 19446582 22411794 31980649 12388423 24658140 15273741 25402006 16799092 9374534 34079125 12354760 10781609 15657067
EGFR LYN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 22973453 24658140 23764002 25402006 16799092 34079125 23866081
YES1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 22430206 11160627
RAP1B GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12005431 9566877 7997267
RAP1A GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12005431 9566877 7997267
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK1 RAP1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
MAPK1 YWHAB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
PPP1CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
RHOA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MAPK1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18378670 7569900 14963018
STAT1 GSTK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
RAP1A SIPA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 1846040 15632203 9346962
ARRB2 AP2B1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21118812 17620599 12070169 10097102
CAV1 FLOT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25204797 10212252 34079125 22936677
ESR2 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20155458 10037443
YWHAE YWHAZ â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
YWHAE DENND1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 26055712 22762500 23684622
RAP1B SIPA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 1846040 15632203 9346962
STON2 EPS15 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18200045 19380743 11381094
ARRB2 ARRB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24069330 17353931 33961781 17620599
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CTNNA1 CTBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SRF ELK4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9271374 11406578 17200232 7854423 11846562
MAPK7 ELK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10473620
PPP1CA PPP1R9B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PPP1CC PPP1R9B â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ACTB CFL2 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
FLOT1 FLOT2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ACTB ACTC â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 16189514 30890647 33961781 34079125 8913639
YWHAZ YWHAE â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20618440 7899808
CTNNA1 JUP â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
CDC42 IQGAP1 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
ANLN RHOA â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
PAK1 CDC42 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5220560 7744004
EGFR EPS15 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 32377695 15701692 16499958 21226813 19109251 10953014 9049247 16429130
IQGAP1 CDC42 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5221163 8798539
CDC42 IQGAP1 â—¼   COLOCALIZATION ✅ 0.95 0.95 mint 18809683
EPS15 STON2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PPP1CC YWHAZ â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CTNNA1 VCL â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
ELK4 SRF â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
FLOT2 SVIL â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
CLTCL1 GAK â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
CAPZA1 CAPZA2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
EGFR GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19254954 7518560 31980649 9416834 7592693 23956138 14679214 10085134 7510700 27059931 21706016 25402006 16799092 16729043 8665853 15657067 24797263 12577067 8810325 7650032 11960376 23799367 25187647 8626525 10026169 19289468 18271526 21278786 7506413 17971399 8940013 20124286 11726515 9886492 10595738 24189400 9020117 19531499 20473329 9020193 8662998 8647858 1322798 8887653 10229072 16273093 25754235 31959764 11370743 16713569 21596750 9685397 24658140 31985874 22973453 11896612 20067773 17242169 19836242 8810340 21278788 30544639 7527043 9050991 11408594 8621459
PAK1 CDC42 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9535855 11157984 21029865 16678097 19596003 23455922 9705280 31871319 25150978 12879077 12606577 10360579 31478661 10684602 8107774 21048135 23175184 18057010 10802735 21167153 15548653 12650940 18426980 7744004 20936779 24276241
FLNB FLNA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22939629 26344197 12393796 26496610
SPTAN1 SPTBN1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CDH1 JUP â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
ACTR2 ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ARPC1B ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CTNNA1 CTNNB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC42 PAK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC3 ARPC5L â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ACTR2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC1B â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ACTR2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
MYH9 ACTR2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
PAK1 ACTR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16293614 10467124 14749719 9843499 16702231 10511705 12054568 8625410
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
CAV1 EGFR â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
CDH1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17548604 10969083 15662113 31980649 14681060 25241761 24189400 25468996 24658140 25402006
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
LYN EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 31980649 16799092 23866081 24658140 11160627 23764002 25402006 22430206
EGFR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19104148 27401557 15371335 16099633 22558232 30747223 12040186 26509276 24816560 12740122 25500543 17318191 19568798 21423209 14585353 34227224 23640056 17496910 17052462 24240237 25164010 14517306 21903109 22200182 16952352 20858269 28035485 9233779
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR EPS15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17145710 17389395 10953014 24269888 19534553 25260758 19583965 19690332 15951569 9049247 17016520
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
EGFR STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 23956138 12070153 11839738 10918587 11447289 11997436 14967450 25402006 12040186 24797263 15173823 7543024 15322115 10358079 6321473 11294897 7690989 10982844 19568798 12637327 14585353 15199124 17496910 11438544 10748192 24658140 7657660 12817007 31980649 22693070 9355737 19615955 11152457 15284024 15567848 7592750 16488589
EGFR CCDC50 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19059208 15951569
EGFR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 31980649 22411794 9374534 19446582 16799092 12388423 15657067 24658140 19625610 16407214 18789131 25402006 15951569 10781609 16332692
FGFR1 GRB2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
GRB2 KSR1 â—¼   PHYSICAL_INTERACTION 53.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11274345 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14724641 14764585 15169888 15173823 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9510155
GRB2 KSR1 â—¼   SHARES_COMPLEX 53.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11274345 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14724641 14764585 15169888 15173823 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9510155
FOS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
GRB2 KSR1 â—¼   ENZYMATIC_REACTION ✅ 53.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11274345 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14724641 14764585 15169888 15173823 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9510155
EPS15 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7797522 17474147 19109251
GRB2 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12522133
CTNNA1 IQGAP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
IQGAP1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15655247 11319218 8226933 1330321 1497021909368021 16135787 17563371 7992057 8248196
IQGAP1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 17145710 9182573 8798539 12377780 9199170 8670801 17563371 8702968 12745076 15695813 21876773 8756646 12900413 18809683
IQGAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12446675 9694656 11734550 12377780 16622255 10473551
LYN PPP1R15A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11517336
MAPK1 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
FGFR1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
KSR1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19219045 19541618 8226933 10567369 1330321 7992057 9858547 8248196
MAPK1 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15616583
MAPK1 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27342992 23405013
MAPK1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19604315 15542607 16964243 15212693 11604394
MAPK1 PPP1R9B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21704645 15980451 15728359
MAPK1 ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19651622 19153083 18767875 17322306 15456867 10347142 20068231 19413330 9388255
MAPK1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 12134156 20506250 15547943 8248197 7816602 15084594 12697810 8226933 20068231 18452278 12738796 16393692 17255949 17439715 15187187 19541618 23109003 19565474 17722974 17052211 7588633 8545107 16055710 8388392 18039929 12972619 18775330 21098038 9604935 11274345
CDC42 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 810774 10360579 21167153 8107774 10559936 9705280 12650940 16678097 23331499 21029865 10684602 18057010 15020669 21070974 11340065 21048135 15003621 20936779 10934474 11413130 15788770 15713627 9535855 23109003 11950587 19628037 7744004 12879077 12606577 24276241 10224076 19596003 8973630 19812368 11248548 10802735 18719708 10613909 10461188 23455922
PAK1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 28007610 12872159 16999872 18354494 20361981 23291169
PAK1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 28007610 28423670 23543898 25639486 26547035 22369945 23162742 25472536 21822311 25225063 27713506 27910850
PAK1 ARPC1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 28007610 20603326 14749719 25472536
PAK1 FLNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 18598695 18088087 24278701 12198493 26009991 15024089 25472536 23246867
PPP1R15A PPP1CC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14670976 23331499 14718519 27629041 11564868
PPP1R9B PPP1CC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10194355 24366813 26186194 28330616 23080069 10391935 26496610 25785436
RHOA PPP1CB â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
MYH9 PPP1CB â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
YWHAB PPP1CB â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
ACTB RHOA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
ACTB CDC42 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24914801 15507212 16439214 22608513
SRF ACTB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18804439 15837932 1762920 9571041
ACTB CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 8913641 25416956 15364581 10592173 19704022 16189514 31515488 32296183 16713569 29892012 10980704
FER JUP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14517306
ARPC1B ARPC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
MYH9 ARPC3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
STAT1 FOS â—¼   UP_REGULATES ✅ + 20.0 1.0 ACSN 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
STAT1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8874187 7510676 8830676 12600988 7507205 8770944 17558387
FGFR1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17496910 11447289 19615955 16488589 6321473 11997436 12040186 19568798 15567848 15173823 14585353 15199124
DAPK1 DAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15611134 15367680 18239682
CLTCL1 AP2B1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
CDH1 CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CTBP1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15169839 17615296 21416054 22796940 20818389 21685935 22370643 20519943 12508111 17508028 11309385 19597490 14673164
CDH1 CTNNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17145710 7542250 19016843 25468996 9326449 16212417 11960376 11801604 8227214 10381631 16219695 9700170 24336504 22750944 9233779 11226248
CDH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 91.0 1.0 Omnipath 17145710 7542250 11348595 9512503 10652321 19016843 16909210 9233779 17220478 16219695 27177845 25344754 11245482 22752307 16983094 16212417 16574648 18593713 9535896 9819408 12830000 10772923 11801604 23180380 8227214 16546130 10085258 22056988 9700170 12640114 24424122 10381631 17087658 24798214 11226248 12875984 9405455 11712088 12061792 17909039 22158051 11960376 14706341 11254878 15023525 12169098 21255999 16125672 22850631 16126725 11113628 25468996 9326449 17524503 17057644 7876318 11401320 22715382 7954478 18593907 21152425 22375065
FOS KSR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
YWHAB PPP1CC â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
YWHAE YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
YWHAB YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
CDC42 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16714282 7512369 9113980 23434736 11306516
FGFR1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17496910 25241761 22558232 11401320 12040186 19568798 14585353
ELK4 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23063436 9734357 8764983 9111305 9130707 8986626 11846562 20637912
SRF FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 9315625 10742173 8864058 8986626 19581295 9690619 10777594 11846562 12242287 2104799 17938209 9111305 8007980 12760745 11862715 1902475 8423791 10642500 10330504 10961986 9032300 2511007 8164681 7854423 17182846 2200737 9271374 10369679 8413226 19173292 9349499 1630900 8262053 10319327 7910456 9545312 9571041 9734357 8764983 12231642 2493627 14693367 18557893 7588632
YWHAH YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
YWHAZ YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
FER CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 22264731 24511551 19166962 14517306 12640114 25803041 19047464
SRF ACTC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15933209 11969255 8887666 17468179 9571041
CFL1 ACTC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12207032 16713569 17196218
CFL2 ACTC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16530787 18957424
SSH2 CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11832213 14531860 16713569