Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ZBTB48 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
DVL2 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DVL2 CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
DVL2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
APP STX6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 ABCC6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374464 17214963
CCT3 ANK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AP2M1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
APP APBA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APBA3 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
HTT APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA5 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CAV1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SQSTM1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAP1LC3B APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP8 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NUCB1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT6A APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CLU APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP PCNT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CASP8 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10409650 10911620
USP13 ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STK36 ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN3 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 BBC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18811981
PDPK1 BCL10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15122200 17468049
FUS BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18471544
BECN1 USP13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21962518 22216260
MAP1LC3A BNIP3L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20010802 7715597
SP1 BNIP3L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16291751
CACTIN RBM8A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TSC1 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GABARAPL1 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CHD3 CASP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CASP8 NUCB1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 6175494 18154733
CAV1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20956295 1005574107
NFE2L2 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23637463 22547061
CAV1 PTPN6 â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
CCT2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT8 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT6A SECISBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT8 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
CLTC RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RAB7A COPS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
COPS3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP3 DNASE2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12694199
EGFR RAB7A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18776048 0806158105
EGFR IRS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
SP3 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20435036 20407012
TSC1 EIF3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HNRNPU EIF3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP3 EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17202795 16394508
KXD1 GABARAPL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TSC1 HNRNPM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HNRNPM PPL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPM USP9X â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPU RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HTT HSPA1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA1A SQSTM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA1A MAP1LC3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA5 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TNIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HYPK HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SECISBP2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZNF436 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TBC1D5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT PRUNE2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NFE2L2 KEAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 19560419 23850759
NFE2L2 KEAP1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19560419 23850759
MAP1LC3B KXD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NBR1 MAP1LC3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19427866 7034152
NBR1 MAP1LC3A â—¼   COLOCALIZATION 2.0 0.8 intact 19427866 7034152
MAP1LC3A SQSTM1 â—¼   COLOCALIZATION 2.0 0.8 intact 19427866 7034152
TP53INP2 MAP1LC3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056683
SQSTM1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SP1 MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18173747
SP3 PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12657578 15777284
SP1 PPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19583808
SQSTM1 PRKAG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRUNE2 RCN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
USP9X RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SPAG8 UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
APBB2 APP â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
EGFR JAK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
SP3 SP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 12414801 11517158 10825178 16734381 9329821 23825960 12200149 15247906
HYPK CHD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16169070 23272104
DDX5 CHD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20676135 28977666
EGFR DDX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28065597 31980649
IRS4 EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16273093 24797263
EGFR PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24780295 28065597
SP1 EPAS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22402494 17024177
KEAP1 NBR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30126895 33545068
LRRK2 LMNB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
TNIP1 NBR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30561431 33545068
PARP1 TOP2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16794079 34079125
MAP1LC3B NBR1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
DDX17 HNRNPM â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HERC2 BIRC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 26186194 25476789
HERC2 EIF3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29426014 30279242 25476789
MAP1LC3A NBR1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
AP2M1 LAMP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 7569928 16189514 16713569 34079125
CHD4 CHD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24981860 28977666 22939629 32744500 9885572
HTT SQSTM1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
AP2M1 BMP2K â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
FUS DDX17 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 27460707 29884807 26344197
CCT2 CCT3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
LRRK2 DVL2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31046837 19625296
RAB7A CAV1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 34079125
AP2A1 AP2M1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
BECN1 AMBRA1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 23974797
APP CLU â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BNIP3 BNIP3L â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CBX5 CHD4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 28977666 32744500 15882967 27705803
DDX17 DDX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EGFR ITK â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
GABARAPL1 SQSTM1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CCT2 CCT8 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CHD3 CHD4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HAP1 HTT â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
HERC2 NEURL4 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
EGFR AP2A1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31959764 24797263 23956138 25754235 20029029 24189400 7534311
BECN1 TSC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28205554 28628118 20562859
JAK2 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24240702 23838182 9363897 10358079 10635327 16273093
CAV1 EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
FUNDC1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
HSPA5 SQSTM1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
H2AFX PARP1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AP2M1 DVL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 31340145
EGFR AP2M1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31959764 24797263 31980649 24067654 23956138 25754235 20029029 24189400
STON2 AP2M1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 11454741 26186194 28514442 19380743
AMBRA1 BECN1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
BBC3 BCL2L1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CCT6A CCT8 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
DDX5 FUS â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
APBB2 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16273093 31980649 25402006 24658140
DOCK7 BCL2L1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
BNIP3L BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10467396 9973195 16189514
CASP8 PTPN6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8296476 18086677 706462200
EGFR CAV1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19446582 15657067 24658140 31980649 22411794 34079125 16407214 12354760 25402006 10781609 9374534 12388423 16799092 15273741
PARP1 CHD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20693977 26565020
SP1 HSPA1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1508207 1717345 2674689
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
MDC1 BCL2L1 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
DDX17 FUS â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CCT3 CCT6A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CCT2 CCT6A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
NBR1 SQSTM1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
CHD4 CHD5 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
BCL2L1 BECN1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
MAP1LC3A SQSTM1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
MAP1LC3B SQSTM1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CCT3 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
SQSTM1 MAP1LC3A â—¼   COLOCALIZATION ✅ 0.95 0.95 mint 19427866 7034152
BNIP3L BNIP3 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 10381623 6594431
AP2A1 AP2M1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
KEAP1 SQSTM1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ATG5 TECPR1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
RBM8A UPF2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
KEAP1 NFE2L2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ATG14 BECN1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT2 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT3 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ATG12 ATG5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCT2 CCT3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
DVL2 LRRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 20006983 19625296
AMBRA1 BECN1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 21358617 22441670 23030059 23377657 23974797
AMBRA1 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 20562859 23974797 20711182 20417604 21358617 25438055 23954414 20921139 24587252 17589504 25499913 33562550
AP2A1 CLTCL1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
CLTCL1 AP2M1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
AP2M1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23956138 31980649 24189400 19351721 20029029 24797263
SP1 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19049493 8427604 15673661 9361293 21557719 18449948 14701757 8015372
ATG5 ATG12 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 22093031 22166994 23030059 23301705 23725295 24070470 24257061
ATG5 ATG12 â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 22093031 22166994 23030059 23301705 23725295 24070470 24257061
ATG12 ATG5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11825910 20562859 17145710 12890687 17353931 22342342 9759731 9852036 23202584 11265251 12207896 12482611
BECN1 ATG14 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
BECN1 ATG14 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
ATG14 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 19270693 19050071 25594178 19223761 18843052 27513923 26496610 23954414 23332761 22081109 20562859 26108642 25891078 24034250 23112296 32296183 24980960 19270696 21062745 20711182 25490155
ATG5 CASP8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
ATG5 CASP8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
BBC3 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 16697956 15694340 19074266 28202514 15574335
BNIP3 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16189514 10625696
BCL2L1 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 33931087 19180116 19049976 22219388 18628207 18641390 17659302 9765397 16713569 19713971 24443581 17446862 17337444
BNIP3L GABARAPL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19363302 20010802
PTPN6 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18086677
CAV1 EGFR â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
SP1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15531587 10684646 23280667 21631282 17108117
EGFR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 31980649 22411794 9374534 19446582 16799092 12388423 15657067 24658140 19625610 16407214 18789131 25402006 15951569 10781609 16332692
EGFR CCDC50 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19059208 15951569
SP1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 1282800 17616668 18575762 19538880 15665278 18202149 20435036 21705183 18007664 21464950 23821666 15533438 9819401 10830317 8393457 16087726 20407012 18391986
JAK2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17389395 10635327 17081983 10358079 16273093 16799092 18691976 10459005 9363897 15284024 23838182 17016520 18669648 15302935
PTPN6 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 9038217 9287352 7673163 7518460 9733788
NBR1 GABARAPL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20562859 21620860 19250911 23022382
GABARAPL1 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17580304 20562859 23022382 21691068 25416956 31053714 16189514 32296183 21617041 19250911
PARP1 H2AFX â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 12607003 14726013 15175241 15459660 15703371 16581787 16697054 17088286 17116881 17303408 17713585 19208614 19364882 19772495 19847258 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9488723
H2AFX MDC1 â—¼   PHYSICAL_INTERACTION 81.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15496928 15549137 15655342 15798197 15964794 16049003 16163361 16332722 16377563 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17349954 17384638 17582221 17660363 18001825 18006705 18087292 18171670 18212739 18469862 18543256 18583988 18584027 18590585 18678709 18678890 18809224 18995830 19151707 19217833 19270065 19282663 19342888 19490890 19622404 19686080 19772495 19793801 19793861 19793862 19841479 20021983 20051983 20064462 20101220 20118229 20723763 21376743 22743550 22771115 23847781 24050180 7575488 9407949 9488723
H2AFX MDC1 â—¼   ENZYMATIC_REACTION ✅ 81.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15496928 15549137 15655342 15798197 15964794 16049003 16163361 16332722 16377563 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17349954 17384638 17582221 17660363 18001825 18006705 18087292 18171670 18212739 18469862 18543256 18583988 18584027 18590585 18678709 18678890 18809224 18995830 19151707 19217833 19270065 19282663 19342888 19490890 19622404 19686080 19772495 19793801 19793861 19793862 19841479 20021983 20051983 20064462 20101220 20118229 20723763 21376743 22743550 22771115 23847781 24050180 7575488 9407949 9488723
PDPK1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 18578522 10896934
PTPN6 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 8943354 21071413 10772872 15983048 18988627
SQSTM1 KEAP1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 15340068 16252010 20531300 21981924 23850759 25002027 26587781 26653790 26794443 27048822 28574505
KEAP1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20452972 20495340 22872865 15983046
SQSTM1 KEAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 20378532 35044719 20495340 25416956 25939382 23117207 32075457 20452972 24322982 20562859 25910212 26043024 33397898 23795962 27631370 33603948 20421418 32296183 23242280 19615732 31169361 20173742 24011591 21482715
KEAP1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 104.0 1.0 Omnipath 30122040 17020408 31257023 35380342 16449638 22245129 18417180 28939422 15475350 24130096 20421418 12145307 32057361 17462537 23727018 24704364 34894983 23857982 19920073 31262713 20599909 36038548 24997453 17015834 23722832 21988832 30778200 24322982 36333711 20486933 30465941 22448038 30576774 21262351 23645672 16888629 31169361 11909699 26078718 25582950 19706542 20463144 16006525 18694732 11439354 15985429 15572695 34815381 28186440 23066931 19560419 15601839 23986495 25628777 27212020 22302998 30793592 16790436 26536456 24512214 17822677 20027226 28533375 22215675 29423025 14517290 32911434 20484052 14585973 18387606 23382044 21383067 32159343 18757741 27091842 24011591 9887101 31941496 22558124 36165926
NBR1 MAP1LC3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23022382 21620860 19427866 19250911 21935636
MAP1LC3A SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 20061800 23022382 23459205 35044719 22963397 36036324 31053714 21045561 25921531 19250911 17580304 21628531 20204693 28740232 23640897 25686248 24100292 26075355 20562859 22658522 25984893 21460636 16286508 19427866 32296183 23989536 19021777 26268733 22714671 24998849 18653543 31366950 33436498 16169070 23239879 26754771
MAP1LC3B NBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 20562859 23022382 21620860 24879152 19250911
MAP1LC3B SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 18083104 23022382 35044719 26413874 25416956 22434781 31053714 24023838 19250911 17580304 23333919 20452972 24668264 28085563 21900206 20562859 20010802 25007327 32296183 33302793 24582747 33436498 16169070
NBR1 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20562859 29343546 16861740 20808283 15802564 24879152 25007327 19250911 12813044 21935636
NFE2L2 SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23382044 19762340 17189831 20452972 24416372
SP1 PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9428683 9493965 17003407 17961220 11278663 12657578 15777284
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
SP1 SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9762895 12736330 17012241
MDC1 PPL â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
MDC1 CAV1 â—¼   KO_UP_REGULATES ✅ + 2.03 2.03 PKG 28854368
MDC1 LGALS3 â—¼   KO_UP_REGULATES ✅ + 2.29 2.29 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368