CCT3
|
ANK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
DVL2
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
AP2M1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
SP1
|
BBC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18811981
|
CCT2
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ATXN3
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CCT6A
|
SECISBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
CCT6A
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
DVL2
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17199046
12958364
|
CLTC
|
RELB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CLU
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
COPS3
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
DDX5
|
HNRNPH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
APBA3
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
JAK2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
EGFR
|
IRS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
SP3
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20435036
20407012
|
NFE2L2
|
KEAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
19560419
23850759
|
NFE2L2
|
KEAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
19560419
23850759
|
NFE2L2
|
KEAP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
19560419
23850759
|
SP1
|
MDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18173747
|
HSPA1A
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SQSTM1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SQSTM1
|
PRKAG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SQSTM1
|
MAP1LC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
MAP1LC3A
|
SQSTM1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
SPAG8
|
UBQLN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
ZBTB48
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
MAP1LC3B
|
KXD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
KXD1
|
GABARAPL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
HNRNPM
|
PPL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SP1
|
PPL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19583808
|
BECN1
|
USP13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21962518
22216260
|
CAV1
|
PTPN6
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
12176037
6731969
|
CHD3
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
CASP8
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CASP8
|
NUCB1
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
6175494
18154733
|
CASP8
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10409650
10911620
|
NFE2L2
|
CAV1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23637463
22547061
|
HNRNPU
|
RELB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSPA5
|
RELB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
DVL2
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17199046
12958364
|
TSC1
|
GFAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
TSC1
|
EIF3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
TSC1
|
HNRNPM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
TSC1
|
CALCOCO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
CAV1
|
MAP1LC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20956295
1005574107
|
CAV1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SP1
|
EPAS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17024177
5219187
|
SP1
|
ABCC6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16374464
17214963
|
SP1
|
BNIP3L
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16291751
|
TBC1D5
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HYPK
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HSPA2
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ZNF436
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SECISBP2
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HTT
|
PRUNE2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HTT
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HTT
|
HSPA1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HTT
|
CHD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
STK36
|
ATXN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
USP13
|
ATXN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NUCB1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HSPA5
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
MAP1LC3B
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APP
|
APBA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APP
|
PCNT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
APP
|
STX6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HNRNPU
|
EIF3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
NBR1
|
MAP1LC3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
MAP1LC3A
|
BNIP3L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20010802
7715597
|
NBR1
|
MAP1LC3A
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
TP53INP2
|
MAP1LC3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19056683
|
GABARAPL1
|
CALCOCO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
HSPA1A
|
MAP1LC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HSPA5
|
TNIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SP3
|
EPAS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17202795
16394508
|
STK36
|
GFAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SP3
|
DNASE2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12694199
|
ZNF436
|
GFAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PRUNE2
|
RCN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
APBB2
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
802.0
|
0.8
|
STRING
|
36370105
|
EGFR
|
JAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
SP3
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
15247906
11517158
10825178
16734381
9329821
12414801
12200149
23825960
|
EGFR
|
DDX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31980649
28065597
|
DDX5
|
CHD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28977666
20676135
|
IRS4
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24797263
16273093
|
KEAP1
|
NBR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33545068
30126895
|
LRRK2
|
LMNB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
23075850
|
SP1
|
EPAS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22402494
17024177
|
TNIP1
|
NBR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30561431
33545068
|
HYPK
|
CHD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23272104
16169070
|
MAP1LC3B
|
NBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
822.0
|
0.82
|
STRING
|
36370105
|
AP2M1
|
BMP2K
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
26186194
33961781
19380743
|
HERC2
|
BIRC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
25476789
26186194
|
HERC2
|
EIF3A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25476789
29426014
30279242
|
AP2M1
|
LAMP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
34079125
16189514
7569928
16713569
|
MAP1LC3A
|
NBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
CHD4
|
CHD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28977666
32744500
24981860
22939629
9885572
|
HTT
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
AP2M1
|
BMP2K
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
LRRK2
|
DVL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
31046837
19625296
|
CBX5
|
CHD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
32744500
27705803
24981860
15882967
28977666
|
EGFR
|
ITK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
BECN1
|
AMBRA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
23974797
|
APP
|
CLU
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
DDX17
|
DDX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
GABARAPL1
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
BNIP3
|
BNIP3L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
FYCO1
|
MAP1LC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
SP1
|
SP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
CHD3
|
CHD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
JAK2
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24240702
9363897
10635327
16273093
23838182
10358079
|
EGFR
|
AP2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24797263
20029029
24189400
23956138
25754235
7534311
31959764
|
HERC2
|
NEURL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
BECN1
|
TSC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
20562859
28628118
28205554
|
HAP1
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
CAV1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
FUNDC1
|
MAP1LC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
HSPA5
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
AP2M1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24797263
20029029
31980649
24189400
23956138
24067654
25754235
31959764
|
STON2
|
AP2M1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
26186194
19380743
11454741
|
AP2M1
|
DVL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31340145
16189514
16713569
|
AP2M1
|
AP2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
24189400
33961781
26186194
19380743
26344197
|
ATG13
|
ATG101
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
8428476
23392225
|
AMBRA1
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
BBC3
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
BNIP3L
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10467396
9973195
16189514
|
APBB2
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24658140
16273093
25402006
31980649
|
EGFR
|
CAV1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16407214
19446582
22411794
31980649
12388423
24658140
15273741
25402006
16799092
9374534
34079125
12354760
10781609
15657067
|
CASP8
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
8296476
18086677
706462200
|
SP1
|
HSPA1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
1508207
1717345
2674689
|
SP1
|
HTT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22399227
20018729
|
SP3
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9329821
15247906
10825178
|
NBR1
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
BCL2L1
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
EIF3A
|
RPS17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
MAP1LC3B
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
MAP1LC3A
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
SQSTM1
|
MAP1LC3A
|
â—¼ COLOCALIZATION
|
✅
|
|
0.95
|
0.95
|
mint
|
19427866
7034152
|
DDX17
|
DDX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
22365833
15298701
19995069
22863883
33961781
24581491
10837141
22939629
|
BNIP3L
|
BNIP3
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
10381623
6594431
|
AP2A1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
ATG5
|
ATG12
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11825910
12890687
12482611
17353931
20562859
23202584
31612776
22342342
33961781
28253979
33024031
32129924
|
KEAP1
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
ATG5
|
TECPR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
ATG101
|
ATG13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
RBM8A
|
UPF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
KEAP1
|
NFE2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ATG14
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ATG12
|
ATG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CLTCL1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
AP2M1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
23956138
31980649
24189400
19351721
20029029
24797263
|
ATG101
|
ATG13
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
20562859
23392225
26299944
19287211
24290141
19597335
24100292
|
BBC3
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17145710
16697956
15694340
19074266
28202514
15574335
|
BNIP3
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16189514
10625696
|
BCL2L1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
33931087
19180116
19049976
22219388
18628207
18641390
17659302
9765397
16713569
19713971
24443581
17446862
17337444
|
CAV1
|
EGFR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
11102446
17517963
18458534
19411448
20855962
21051947
21150282
21729786
22411312
22874531
23907124
25364523
26828520
|
SP1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
1282800
17616668
18575762
19538880
15665278
18202149
20435036
21705183
18007664
21464950
23821666
15533438
9819401
10830317
8393457
16087726
20407012
18391986
|
JAK2
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17389395
10635327
17081983
10358079
16273093
16799092
18691976
10459005
9363897
15284024
23838182
17016520
18669648
15302935
|
PTPN6
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
9038217
9287352
7673163
7518460
9733788
|
EGFR
|
CCDC50
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19059208
15951569
|
EGFR
|
CAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17145710
31980649
22411794
9374534
19446582
16799092
12388423
15657067
24658140
19625610
16407214
18789131
25402006
15951569
10781609
16332692
|
SQSTM1
|
KEAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
15340068
16252010
20531300
21981924
23850759
25002027
26587781
26653790
26794443
27048822
28574505
|
KEAP1
|
MAP1LC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
20452972
20495340
22872865
15983046
|
SQSTM1
|
KEAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
15340068
16252010
20531300
21981924
23850759
25002027
26587781
26653790
26794443
27048822
28574505
|
SQSTM1
|
KEAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
34.0
|
1.0
|
Omnipath
|
20378532
35044719
20495340
25416956
25939382
23117207
32075457
20452972
24322982
20562859
25910212
26043024
33397898
23795962
27631370
33603948
20421418
32296183
23242280
19615732
31169361
20173742
24011591
21482715
|
KEAP1
|
NFE2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
104.0
|
1.0
|
Omnipath
|
30122040
17020408
31257023
35380342
16449638
22245129
18417180
28939422
15475350
24130096
20421418
12145307
32057361
17462537
23727018
24704364
34894983
23857982
19920073
31262713
20599909
36038548
24997453
17015834
23722832
21988832
30778200
24322982
36333711
20486933
30465941
22448038
30576774
21262351
23645672
16888629
31169361
11909699
26078718
25582950
19706542
20463144
16006525
18694732
11439354
15985429
15572695
34815381
28186440
23066931
19560419
15601839
23986495
25628777
27212020
22302998
30793592
16790436
26536456
24512214
17822677
20027226
28533375
22215675
29423025
14517290
32911434
20484052
14585973
18387606
23382044
21383067
32159343
18757741
27091842
24011591
9887101
31941496
22558124
36165926
|
H2AFX
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
81.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15496928
15549137
15655342
15798197
15964794
16049003
16163361
16332722
16377563
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17349954
17384638
17582221
17660363
18001825
18006705
18087292
18171670
18212739
18469862
18543256
18583988
18584027
18590585
18678709
18678890
18809224
18995830
19151707
19217833
19270065
19282663
19342888
19490890
19622404
19686080
19772495
19793801
19793861
19793862
19841479
20021983
20051983
20064462
20101220
20118229
20723763
21376743
22743550
22771115
23847781
24050180
7575488
9407949
9488723
|
H2AFX
|
MDC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
81.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15496928
15549137
15655342
15798197
15964794
16049003
16163361
16332722
16377563
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17349954
17384638
17582221
17660363
18001825
18006705
18087292
18171670
18212739
18469862
18543256
18583988
18584027
18590585
18678709
18678890
18809224
18995830
19151707
19217833
19270065
19282663
19342888
19490890
19622404
19686080
19772495
19793801
19793861
19793862
19841479
20021983
20051983
20064462
20101220
20118229
20723763
21376743
22743550
22771115
23847781
24050180
7575488
9407949
9488723
|
H2AFX
|
MDC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
81.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15496928
15549137
15655342
15798197
15964794
16049003
16163361
16332722
16377563
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17349954
17384638
17582221
17660363
18001825
18006705
18087292
18171670
18212739
18469862
18543256
18583988
18584027
18590585
18678709
18678890
18809224
18995830
19151707
19217833
19270065
19282663
19342888
19490890
19622404
19686080
19772495
19793801
19793861
19793862
19841479
20021983
20051983
20064462
20101220
20118229
20723763
21376743
22743550
22771115
23847781
24050180
7575488
9407949
9488723
|
NFE2L2
|
SQSTM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23382044
19762340
17189831
20452972
24416372
|
SP1
|
SQSTM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9762895
12736330
17012241
|
NBR1
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
20562859
29343546
16861740
20808283
15802564
24879152
25007327
19250911
12813044
21935636
|
GABARAPL1
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
17580304
20562859
23022382
21691068
25416956
31053714
16189514
32296183
21617041
19250911
|
MAP1LC3A
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
20061800
23022382
23459205
35044719
22963397
36036324
31053714
21045561
25921531
19250911
17580304
21628531
20204693
28740232
23640897
25686248
24100292
26075355
20562859
22658522
25984893
21460636
16286508
19427866
32296183
23989536
19021777
26268733
22714671
24998849
18653543
31366950
33436498
16169070
23239879
26754771
|
MAP1LC3B
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
18083104
23022382
35044719
26413874
25416956
22434781
31053714
24023838
19250911
17580304
23333919
20452972
24668264
28085563
21900206
20562859
20010802
25007327
32296183
33302793
24582747
33436498
16169070
|
BECN1
|
ATG14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
BECN1
|
ATG14
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
AMBRA1
|
BECN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
21358617
22441670
23030059
23377657
23974797
|
ATG14
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
19270693
19050071
25594178
19223761
18843052
27513923
26496610
23954414
23332761
22081109
20562859
26108642
25891078
24034250
23112296
32296183
24980960
19270696
21062745
20711182
25490155
|
AMBRA1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
20562859
23974797
20711182
20417604
21358617
25438055
23954414
20921139
24587252
17589504
25499913
33562550
|
PTPN6
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
8943354
21071413
10772872
15983048
18988627
|
PTPN6
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18086677
|
ATG5
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11003656
15325588
17462996
20531300
23725295
24070470
26587781
26972597
28574505
9488730
|
ATG5
|
ATG12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
ACSN
|
22093031
22166994
23030059
23301705
23725295
24070470
24257061
|
ATG5
|
ATG12
|
â—¼ SHARES_COMPLEX
|
|
|
7.0
|
1.0
|
ACSN
|
22093031
22166994
23030059
23301705
23725295
24070470
24257061
|
ATG5
|
CASP8
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11003656
15325588
17462996
20531300
23725295
24070470
26587781
26972597
28574505
9488730
|
ATG12
|
ATG5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
11825910
20562859
17145710
12890687
17353931
22342342
9759731
9852036
23202584
11265251
12207896
12482611
|
DVL2
|
LRRK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
20006983
19625296
|
SP1
|
CAV1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15531587
10684646
23280667
21631282
17108117
|
SP3
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
21554857
12509426
9632663
10362515
19223508
15857802
20096088
16806531
15854045
15118068
9788252
12773549
16617124
11517158
12554796
9666093
15869407
12888570
11287330
15541732
8845379
16574784
8070411
|
SP1
|
APP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19049493
8427604
15673661
9361293
21557719
18449948
14701757
8015372
|
AP2A1
|
CLTCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
NBR1
|
MAP1LC3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23022382
21620860
19427866
19250911
21935636
|
FYCO1
|
MAP1LC3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
27246247
26468287
20562859
|
MAP1LC3B
|
NBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
20562859
23022382
21620860
24879152
19250911
|
NBR1
|
GABARAPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
20562859
21620860
19250911
23022382
|
FYCO1
|
MAP1LC3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
27246247
26468287
20100911
20562859
|
BNIP3L
|
GABARAPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19363302
20010802
|