Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ERG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25277175 20820186
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
AR PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 20610535
NRG1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23966855 22757963
SMARCE1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18238828 19785031
SMARCA4 SMARCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10078207 16713569
AR SMARCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15923603 20610535
SMARCC1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15923603 18581278
YY1 CTCF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9756895
WDR5 CHD8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7542690 20085832
LHX2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19146846 24262147
ESR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16144913
ESR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16144913
ESR1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
ERG AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8388477 22531786
GATA2 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24423874
MYB AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12096342 18945670
HNF4A AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16474850 12466965
GATA3 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21536859
MYB PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9371644 7838532
MYB GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17641686
SOX10 SOX6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17084361
CTCF PARP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 20038529 14759373 19450526
PPARG ASH2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19047629 24368734
SOX2 ASH2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30089852 35140242
BRD7 MYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20215511 35140242
MYC SMRC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC CHD8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC CHD7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
CHD7 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20130577
PPARG RBBP5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19047629 24368734
RBBP5 SOX2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30089852 35140242
SOX2 MTA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21532573 23667531
SOX2 TEAD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
CHD7 SMCA4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21532573 20130577
CHD7 SMCE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21532573 20130577
SOX2 SMRC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
CHD7 SMRC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21532573 20130577
SMARCD1 SMARCD3 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
BRD7 ARID2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30940648 18809673 24657164 24981860 26344197
ARID2 SMRC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 20305087 24981860 15985610
SMCE1 BRD7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 30940648 18809673 33961781 20305087 26186194 24981860
SMRC2 BRD7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 30940648 33961781 20305087 24981860
WDR5 SOX2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30089852 35140242 29383478
ESR1 MTA1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ESR1 MTA2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18451880 16645043
SOX5 SOX6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 9755172 33961781
ESR1 ASH2L â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21502505 16603732 31527615
ESR1 RBBP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21502505 16603732 31527615
SMARCD1 SMARCC1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 34591612
CHD8 WDR5 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
LHX4 ARID2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 35140242 26186194
ASH2L CHD8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20085832 24705355
MYC WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 27320920 35140242 29467282 31767764 30415952
CHD8 RBBP5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20085832 24705355
SOX2 CHD7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 21532573 28794006 23667531
BRD7 SMARCE1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GATAD2A MTA2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BRD7 PBRM1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PBRM1 SMARCE1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
GATAD2A MTA1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ARID2 SMCE1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 18809673 33961781 20305087 26186194 24981860 15985610
ARID2 SMCA4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 30962207 22140357 24981860 31043422 29374058 15985610
ERG PARP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24591637 21575865
ESR1 BTF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31527615 18025262
ESR1 GATA3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26153859 23403292 25303530
MTA2 MTA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24981860 21670149 12920132 34026424 26344197
CHD7 CHD8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20453063 24705355
SMARCD1 SMARCD2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ARID2 SMARCE1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ARID2 BRD7 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
BRD7 SMARCD1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
SMCA4 PAX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 35140242 16675956
MTA1 MTA2 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
ASH2L WDR5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31544921 17925232 16253997 20305087 21285357 15960975 21531708 15199122 17178841 25666610 16892064 15960974 18066051 23870121 23508102 21884981 32076268 33022573 22939629 16878130 31076518 27705803 19556245 17500065 19131338 33961781 24981860 16603732 26186194
ASH2L RBBP5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25416956 31544921 17925232 12482968 16253997 21124902 20305087 21516116 21285357 32296183 21220120 15199122 17178841 16892064 15960974 23870121 23508102 26886794 16878130 31076518 17500065 19556245 19131338 33961781 24981860 16603732 23414517 34079125
MYC BRD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19111069
MYC SMCA4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11839798 28628118 17353931 29467282 28205554 30415952 14559996
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
SMARCC1 SMARCE1 â—¼   UP_REGULATES ✅ + 0.9 0.9 Signor 20829358
WDR5 CHD8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15960975 20085832 24705355 18378692
MTA1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16807247 31527615 12167865 12639951 11146623 18451880
SMCA4 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18451880 9099865 11003650
SMCE1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31527615 16538531 17363140 23403292 12145209
SMCA4 SMCE1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 19164553 12368262 18809673 20305087 16940996 20460684 16287714 30962207 9845365 8895581 22939629 14559996 11003653 33961781 24981860 26186194 31043422 12192000 29374058 26344197
PAX6 PAX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10804178 11003833 12721955
SMCE1 SMRC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19164553 28514442 19650111 9845365 18809673 33961781 20305087 26186194 24981860 16940996 22939629 16199878 26344197
CTCF NES â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
SMARCC1 SMARCC2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ARID2 SMARCC2 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
LHX4 YY1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
ARID1A SMARCD3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ARID1A SMARCD2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
ARID2 SMARCD1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
SMARCC1 SMARCD3 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
SMARCC1 SMARCA4 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 24981860
SMARCD2 SMARCE1 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
SMARCD3 SMARCE1 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
SMARCC2 SMARCD2 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
ARID1A SMARCC1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ARID2 PBRM1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
SMARCC1 SMARCD2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
SMARCC2 SMARCD3 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
NLK MYB â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 15082531 16055500 15308626
SMARCA4 SMARCD2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
SMARCC1 SMARCD1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
PBRM1 SMARCD1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
PBRM1 SMARCC1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
SMARCA4 SMARCD3 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
SMCA4 SMRC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 10078207 12368262 18809673 20305087 11726552 18086889 20460684 30962207 9845365 8895581 23540691 22939629 15985610 26344197 14559996 22573825 33961781 24981860 31043422 29374058 9584200
PBRM1 SMARCA4 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PBRM1 SMARCC2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
SMARCC1 SMARCE1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
ARID1A SMARCD1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ARID2 SMARCA4 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
SMARCD1 SMARCE1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
ARID1A SMARCE1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
ARID1A SMARCC2 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
RBBP5 WDR5 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 31544921 17925232 16253997 20305087 15960975 30089852 21531708 21220120 15199122 17178841 25666610 31685992 15960974 27320920 23508102 21884981 32076268 33022573 16878130 28813667 17041588 31076518 17500065 19556245 27705803 24981860 33961781 16603732 26186194 31400120
SMARCC2 SMARCD1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ARID1A SMARCA4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMARCA4 SMARCD1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCA4 SMARCC2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SMARCA4 SMARCC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SMARCC2 SMARCE1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RBBP5 WDR5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMARCA4 SMARCE1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ASH2L RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L WDR5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L WDR5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
KLF8 MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
MYC PPARG â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
CTCF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10625678 8649389 2284094 12032779 19568426 24725430 12524457 8246978 12897849 9591631 1795697
GATA2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19522008 22951020
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
PPARG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11973610 17462534 16405739 19075513
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23277454 12695333
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
MTA1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
WDR5 RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
SMARCA4 SOX10 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10757804 16373334 17325040 23874858
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
SMARCA4 SMARCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10078207 12917342 23540691 9891079 28420882
GATA3 YY1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
GATA3 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18522800 15632071 15896659
GATA2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18522800 19772889 15896659
GATA3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17616709 20130088 20068169
MTA1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15226262 11146623 12527756 24413532
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
MTA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11146623 18451880 12167865 16807247
ESR1 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26153859 25303530 10096242
HNF1B HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10518495 8290348 11585914 16479257
NLK HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14960582 18855897 11274345 20194509
TEAD1 SOX10 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11394999 28852375 14664827 22492709 12056842 21411665 27288457
NLK MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 15308626 15082531 12482967
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870