PKG

Protein list:

MTA1 PRKCI LYN PDGFRB STK40 MKNK1 MAPK1 EPHB3 MAPK12 CSK SGK1 MAP2K7 PIM1 TBK1 TYK2 FGFR1 BMX PTK2B STK38 RAF1 GSK3B LCK MET DYRK1B WEE1 AKT1 PRKCA CSNK2A2 CDK5 SRPK1 PAK1 PBK BMPR1B FYN HIPK1 NEK2 BCAS3 PLK3 MAST1 MAPK10 ZAP70 BMPR2 MAST2 SNRK PRKCQ NEK4 TNK2 ARAF NEK3 PRKCZ MAPK9 STK17A AXL PTK6 CHEK2 FGFR2 RPS6KA5 IGF1R SYK PRKACB MAX AURKB CDK4 CLK2 PAK4 ERBB2 STK4 PXK RPS6KA4 SRPK2 MKNK2 LGALS7B MMP9 KIT JAK2 DDR1 RPS6KA3 STYK1 CSNK1E MAP2K2 COP1 HIF1A POLR2A PUF60 BPTF KIAA1429 SIN3A POGZ DHX9 ZMYM4 SF3B1 ILF3 SNRPD3 CPSF2 CDC73 EHMT2 SF3B3 HNRNPU KDM1A CHD3 NXF1 CHD5 ZFPM1 BLOC1S1 SENP1 RNF144A PRMT5 E2F1 ITGB3BP HSF1 FOXP1 NR2C1 KHDRBS2 RRM2B PHF1 KPNA3 CUL4B MAK ZFPM2 FOXK2 EGFR SAT1 LMO4 VIM ZNF827 KRT40 ZBTB2 PAX5 PIK3R1 GNAI2 HIC1 GRK4 ARNTL SCYL1 CDKN1A NCK1 CXCL2 GRB2 TRIM25 SMAD7 GATAD2A ZMYM3 VTN DNMT3B HSPA8 LZTS2 SNAI2 PRDM16 RBBP4 RAD21 MBD3L2 NOTCH2NLA H3C2 PHF21A MBD3 HDAC2 CHD4 PDPK1 PITX3 CDK7 MDM2 KRTAP10-8 BAZ1A GSE1 BCL11B HIST2H3C JUN MNAT1 HMG20B NAA10 CCNH HDAC1 GTF2I DLST ESR1 PLEKHG4 MBD2 MECOM ZEB2 SMC1A RCOR1 ZMYM2 SMARCA5 STAG1 SMC3 STAG2 NR2C2 MTA2 RBBP7 CLOCK RBX1 NRG1 KPNA4 SIX3 H4C6 MYC IKZF1 TH PTEN EPHA2 SIRT1 CYSRT1 TNF CRY1 TGM2 BRCA1 ZRANB1 UBE2I IL1B TFF1 RHO BCL2L1 VEGFA CAT DYNLL1 POLD3 CHD7 SUMO2 CDKN2A HMMR SNAI1 MYD88 WNT1 FASLG DDB1 ALOX15 GOLGA2

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Protein:

Eg: PBRM1 | ARID1A | BRCA1

Function:

Eg: Homologous recombination

Path:

Eg: SMC5 > DMC1 | PBRM1 > BRCA2

Relationship:

Full list of relationships

Graph tools:

Note this may take some time with > 30 proteins

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PKG Score Threshold: 0.8

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Source	Target	Relationship Type	Directed	Sign	DB Score	PKG Score	Database	References
AKT1	PTK6	◼ PHYSICAL_INTERACTION			2.0	0.8	Reactome	15539407 20606012
AKT1	CDKN1A	◼ ENZYMATIC_REACTION	✅		2.0	0.8	Reactome	12244303 11231573
AKT1	MYC	◼ POST_TRANSLATIONAL_REGULATION	✅	-	2.0	0.8	Omnipath	17942906 9804616
AKT1	MDM2	◼ PHOSPHORYLATION	✅		0.81	0.81	mint	5217292 15527798
AKT1	CSK	◼ PHYSICAL_INTERACTION			0.82	0.82	HIPPIE	19262695 26344197
AKT1	GSK3B	◼ DOWN_REGULATES	✅	-	0.82	0.82	Signor	15829723
AKT1	GSK3B	◼ PHOSPHORYLATION	✅	-	0.82	0.82	Signor	23552696
AKT1	CDKN1A	◼ PHOSPHORYLATION	✅	+	0.83	0.83	Signor	31575057
AKT1	BRCA1	◼ PHYSICAL_INTERACTION			835.0	0.83	STRING	36370105
AKT1	PTEN	◼ PHYSICAL_INTERACTION			852.0	0.85	STRING	36370105

Showing 1 to 10 of 1,159 entries