Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CREB1 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9926942 6548521
BRCA1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 12700228
RSL1D1 DST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CSTF3 DST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SSB DST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GRB2 DST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
PRKD2 DST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PTGER4 DST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
ATP1A2 DST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMAD9 DST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PAK2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218167 16374509
CELSR3 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABI1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
GRB2 HOXC8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 TGOLN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 MYH9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PLEC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
TP63 PLEC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28595999
NFKB1 OPTN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19340308
MYH9 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 10639334 10047984
MYH9 PRKD2 â—¼   COLOCALIZATION 2.0 0.8 intact 22909819 8413258
ITGA6 ITGB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 19161977 22118458
ITGA6 ITGB4 â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 19161977 22118458
LAMB3 ITGA6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8143784 32196115
NFKB1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114294
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
CREB1 NTRK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15234351 17553693
CREB1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10698518
GSK3B NBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24879152
UBQLN1 PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD9 RANBP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 TERF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 PLEC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 1204073 5215931 11244506
CDC5L EXOC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 17043677
CDC5L ANLN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20467437 31586073
ANLN MYH9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
NFYC NFKB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BMI1 PLEC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 RNPS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
CFTR DCTN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CFTR LAMB3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
ANLN PLEC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ESR1 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
GRB2 PDGFRB â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
STK3 MOB1B â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 21808241
BRCA1 TERF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34112789 19797051 29656893
BRCA1 TERF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34112789 25184681 19797051 29656893
CDC5L DISC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
MOB1B MOB1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 24366813 33961781
DCTN1 DISC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
EXOC1 DISC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
ERBB2 EPHA2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 30898150 28628118 28205554
ESR1 MED4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 31527615
PTPN11 ERBB2 â—¼   DEPHOSPHORYLATION ✅ - 0.84 0.84 Signor 32024694
MOB1B STK3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ESR1 MYH9 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21182205 19805454 25604459
CFTR MYH9 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22038833 29924966 26618866
ERBB2 GRB2 â—¼   RELOCALIZATION ✅ + 0.85 0.85 Signor 14967450
RNPS1 PUF60 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 33961781
PAK2 RAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12176041 31871319
STK3 MOB1A â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 23431053
MAGEA1 S100A9 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
DTNBP1 SNAPIN â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CTBP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21102443 16713569 10196224 31636387 11751867
DCTN1 GRB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8955163 16189514
GRB2 MYH9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12577067 20936779 24189400
GSK3B NBR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29568061 24879152
ERBB2 ERBB2IP â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
APC MAPRE1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
NTRK1 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11733534 25921289 10748052
FGFR2 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24440983 22726438
STK3 MOB1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18362890 31941533 24255178 23972470
STK3 MOB1B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24255178 32296183 19919647
TNIK DISC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 29961565 90000000 31413325 17043677
CDC5L ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
FGFR2 GRB2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HOXC8 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
ESR1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 1244506 11782371 15674350 29367421 27977889 17392432 16860316 10334989 16260778 11244506 16061635 12400015 17505062 20060929 25499220 16713569 31527615 11493692
DISC1 CEP63 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 90000000 31413325 17043677 12812986
ITGA6 DST â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12482924 9856810 15265795
ITGB4 DST â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12482924 9856810 15265795
CD151 DST â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12482924 9856810 15265795
DST LAMC2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12482924 9856810 15265795
DST LAMA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12482924 9856810 15265795
DST LAMB3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12482924 9856810 15265795
IRF1 DST â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15560761
PDGFRA GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7935391 8388543 9739761
PDGFRB PTPN11 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
PTPN11 PDGFRB â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 8119896 6730513
S100A9 RAC2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
IRF1 OPTN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23811275
UBXN6 GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RANBP9 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LAMA3 ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12867433 8143784 32196115
LAMB3 ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12867433 8143784 32196115
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
APC GSK3B â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
GRB2 ERBB2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 16273093 5218056
APC CTBP1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 31041561 16510875 26496610 15525529 33961781 35016035 26186194
ERBB2 PTPN11 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
GRB2 PTPN11 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
TOMM20 TOMM22 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
ERBB2 GRB2 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
DCTN1 MAPRE1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MOB1A STK3 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
APC GSK3B â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11166179 29045831 21118991 8638126 11251183 23602568 29568061
ERBB2 GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9710588 11173924 21278786 16713569 9756944 24189400 31980649 22973453 24658140 30898150 16273093 17875712 16729043 11606575 8665853
ITGB4 PLEC â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
DST MAPRE1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
GSK3B APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 16944320 11166179 16799642 11967263 14663202 8524413 12554650 8638126 17910481 15327768 10581160 11487578 17318175 15465828 10228155 15020233 10421629 10698523 9832503
APC CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15525529
CREB1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9528858 19882681 18160048 23447579 11704836
CTBP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20818429 21681822 23303449
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
PTPN11 GRB2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10358138 11447289 11572860 12138178 12707331 15240681 15699106 15713798 19833085 9751747
PDGFRB GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7935391 16713569 7486683
ERBB2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 31980649 9756944 21278786 16273093 24189400 11173924 9710588 24658140 11606575 14967450 17875712 16713569 16729043
FGFR2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22726438 19735729 26103942 20554525 23420874
NTRK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733534 10748052
PTPN11 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 8702859 9361008 16371368 21706016 8041791 11085989 8978300 11432792 15882975 9362449 10212213 11684012 7523381 10592173 16189514 10747947 10973965 9632781 8959326 11602579 12577067 9254654 10080542 15010462 31585087 12531430 8995399 19380743 7522233 9804835 7534299 9824671 9660791
PDGFRB PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 8622870 19690332 8041791 18083107 8538796 23331499 19534553 11684012 7530043 16189514 12721296 12522270 8959326 17287340 16094384 7688466 8226787 8119896 12531430 11266449 12681492 12614164 8183548 23397142 7691811
PTPN11 ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9756944 16273093 16729043 32024694
MAPRE1 TERF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 17145710 11701125 11943150
PDGFRB PDGFRA â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
PDGFRB PDGFRA â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
PDGFRB PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 21071413 2161888 2542288 7523122 1847074 16189514 11331882 10417313
LAMC2 ITGA6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10842354 8143784
NFKB1 IRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12077266 18694960 17274000 12595462
GSK3B NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 26999213 12871932 11425860 24618402 18669648 17693123
IRF1 IRF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 7630638 7507207 9054665 8152803 15560761 10321737 12493643 1431317
GSK3B CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16568235 12162494
PAK2 MAPK6 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 21372320 21177870 18720373 21317288 18248330 17161475
STK3 MOB1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23972470 18362890 23431053 21808241 32513747 30038061
STK3 MOB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19878874 32296183 23431053 21808241 18328708 19919647
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
ESR1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 24559156 16115928 16467118 17992604 19915977 15199112 21127199 21761336 21907803 20551150 11713584 1358436 20629094 18768663 19005469 9242384 20889718 10698518 16467117
ERBB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 15173068
LAMC2 ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12867433 10842354 8143784