Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
BRCC3 NLRP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32941940 30787184
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
WWP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
ZRANB1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
UBC ZRANB1 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
BRE BRCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21282113 19261749 19261746 30755420 19261748 17353931 20656689 14636569 33961781 20032457 19615732
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
BABAM1 SHMT2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
BRCC3 BRE â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BRCC3 SHMT2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BRE FAM175B â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BRE SHMT2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
FAM175B SHMT2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BABAM1 FAM175B â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
BABAM1 BRCC3 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
UBC ZRANB1 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
UBC USP7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
BRCC3 FAM175B â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BABAM1 BRE â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066