Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ZRANB1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
UBC ZRANB1 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
CSK PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18173375 18759926
CSK PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 15574420 14665621
BCAS2 SF3A1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
BRAF PPP5C â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16892053 21779496
BRCC3 NLRP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32941940 30787184
EIF2B5 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 DYNC1H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9781666 9627114
IFNAR1 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 10022928 18508557
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
TP53 PRKAA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
UBC TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18636086 6804508
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
UBA6 UBC â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
WWP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
GCN1L1 NAA25 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
COPA SF3A1 â—¼   CORRELATES - -0.82 0.81 CCLE 31978347
ETF1 HARS â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EEF2 ETF1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DYNC1H1 UBR4 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
ACTR10 DCTN1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
EPRS IARS â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ACTR10 DYNC1H1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
SNF8 VPS25 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
BCAS2 SF3A1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
AP3M1 AP3D1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 23144738 26344197 28514442 22863883
KIAA0196 KIAA1033 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AP3D1 AP3M1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
ACTR10 ACTR1A â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
COPG1 COPA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 14729954 26344197 22939629 28514442 9751720
ABCE1 NAA15 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
AP3B1 AP3M1 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
AP3B1 AP3D1 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
BRAF MAPK3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
BRE BRCC3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20656689 17353931 19615732 19261748 30755420 14636569 19261746 21282113 20032457 19261749
MAPK3 PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8197172
VPS25 SNF8 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 8153045 21516116
ACTR1A DCTN1 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
ACTR1A DYNC1H1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
ACTR10 DCTN1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
KIAA0196 KIAA1033 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
ABCE1 RPS3 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
COPB2 COPG1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
COPA COPG1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
COPB1 COPG1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
COPA COPB1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
EEF2 RPS3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
COPB1 COPB2 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
COPB2 COPA â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 9482852 14729954 10921873 26344197 22939629 8940050 8537409 22863883 9751720
COPA COPB2 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
COPB1 COPG1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ACTR1A DCTN1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
AP3B1 AP3M1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
COPA COPG1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ABCE1 ETF1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
COPB2 COPG1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
AP3D1 AP3M1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP3B1 AP3D1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
BABAM1 SHMT2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
BRCC3 BRE â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BRCC3 SHMT2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BRE SHMT2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BRE FAM175B â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
FAM175B SHMT2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BABAM1 FAM175B â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
UBC ZRANB1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
BABAM1 BRCC3 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
UBC USP7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
BRCC3 FAM175B â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
EPRS IARS â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
ACTR10 ACTR1A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
DCTN1 DYNC1H1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
COPA COPB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COPB1 COPB2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
BABAM1 BRE â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPA COPB2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SNF8 VPS25 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
DYNC1H1 ACTR10 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
MAPK3 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 14654779 21478863 19541618 21135229 16508002 19933846 15664191 8621729
GDI1 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
GDI2 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
MAPK3 RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20041225 15950189 21738525
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
PRKAA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28797070 15866171
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066