BRCC3
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19202061
0807485106
|
BRCA2
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19369211
0811159106
|
TP53
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1003689107
20421506
|
UBC
|
COPS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7229502
19214193
|
UBE2D1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
TP53
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
SUMO2
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22661230
22635276
|
UIMC1
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19433585
|
SUMO2
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19956565
1000252
|
SUMO2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1004248107
20534433
|
TP53
|
FAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9841917
|
TP53
|
BARD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14636569
15782130
|
ZRANB1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
UBC
|
ZRANB1
|
â—¼ DEUBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
SUMO2
|
MDC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
22661230
19394292
19471022
32786267
|
MDC1
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
817.0
|
0.81
|
STRING
|
36370105
|
MDC1
|
BRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22990118
29656893
|
MDC1
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
14578343
18471438
|
MDC1
|
BRE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22990118
29656893
|
MDC1
|
F175A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22990118
29656893
|
MDC1
|
BABA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22990118
29656893
|
UBC
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
19166840
6823655
|
DEFI6
|
BRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
BARD1
|
MDC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12611903
29656893
|
BRE
|
CH3L1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DEFI6
|
BRE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DEFI6
|
F175B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DEFI6
|
BABA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
BABA1
|
F175B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
26195665
28514442
31142841
21282113
30755420
25283148
33961781
26186194
19615732
24075985
|
BRCA1
|
NCOA3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
14578343
16860316
|
MDC1
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28973861
16186822
|
BARD1
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
BARD1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
848.0
|
0.84
|
STRING
|
36370105
|
BABA1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
19261749
19261746
25184681
22792303
29656893
|
SUMO2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
20016603
20016594
22689573
21693764
21147198
|
BRCC3
|
BABA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
21282113
19261749
19261746
30755420
19261748
33961781
26186194
20032457
19615732
|
UBC
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
17290220
19166840
18566590
19098711
|
BABA1
|
UIMC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
21282113
19261749
19261746
19261748
33961781
26186194
28569838
19615732
|
BABA1
|
F175A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
21282113
19261749
19261746
19261748
20656689
33961781
22792303
26186194
22357538
19615732
24075985
|
BABA1
|
GLYM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
31253574
33961781
26186194
19615732
|
TP53
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
F175B
|
GLYM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
28514442
31142841
31253574
33961781
24075985
|
BRCC3
|
BARD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
14636569
17664283
17525341
|
BRE
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
BABAM1
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
COPS5
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
BRE
|
FAM175A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BRCA2
|
BRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
14636569
17664283
|
BRCC3
|
GLYM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
19615732
33961781
31253574
|
SUMO2
|
UIMC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19471022
23211528
32786267
22689573
21693764
26719330
|
BARD1
|
UIMC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19615732
17525341
|
UIMC1
|
BRE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21282113
19261749
19261746
19261748
17525341
20656689
19015238
19615732
|
BRE
|
F175A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21282113
19261749
19261746
19261748
20656689
19615732
24075985
|
BRE
|
GLYM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
19615732
33961781
31253574
|
BABAM1
|
FAM175A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
BARD1
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
MDC1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21622030
19766185
15569676
12611903
17525332
12607005
29656893
|
UIMC1
|
BRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
18077395
19305427
21282113
19261749
19261746
23264621
19261748
19202061
17525341
20656689
19015238
19615732
|
BRCC3
|
F175A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
18077395
21282113
19261749
19261746
19261748
20656689
22357538
19615732
20656690
24075985
|
BRCC3
|
F175B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
26195665
28514442
31142841
21282113
30755420
25283148
22863883
33961781
26186194
33107021
20032457
19615732
20656690
24075985
|
UIMC1
|
MDC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21622030
22990118
21857162
24240613
29656893
|
BARD1
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14636569
32347575
28976962
25252691
|
RAD51
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
BRCA1
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
BRE
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14636569
22990118
25184681
29656893
|
RAD51
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31270457
31009828
11498787
16713569
19766185
25659039
19369211
25499220
9774970
28319063
17302439
9008167
14636569
28976962
24085845
34408138
29656893
|
F175A
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19305427
21282113
19261749
19261746
19766185
19261748
17525340
17643122
30257991
25184681
28398198
26778126
17643121
22357538
23416467
29656893
|
BRCA2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11477095
17664283
16713569
21135251
19369211
9774970
25184681
14636569
24085845
34408138
25652403
14499622
29656893
|
BRCA1
|
BRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19305427
17664283
19202061
22990118
25184681
14636569
25252691
29656893
|
BRCA1
|
UIMC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21622030
17525340
25184681
17525341
17643121
29656893
19305427
26446986
25252691
26027929
28569838
19766185
19261748
34408138
29499138
19615732
17525342
17621610
31932421
24085845
|
BRCA1
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16713569
9774970
9008167
|
BRCA2
|
BARD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14636569
17664283
16391231
19176389
|
BRE
|
BRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21282113
19261749
19261746
30755420
19261748
17353931
20656689
14636569
33961781
20032457
19615732
|
COPS5
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18926707
17879958
|
TP53
|
SUMO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
24782567
25218447
21900752
|
F175A
|
UIMC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21282113
19261749
23264621
17525340
17643121
20656690
19305427
19261746
25252691
19015238
28569838
22357538
17643122
19261748
20656689
28242625
19615732
24075985
18077395
|
BRE
|
BABA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
16189514
21282113
19261749
19261746
19261748
17353931
20656689
22863883
33961781
26186194
19615732
26344197
28009280
|
BRE
|
F175B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26195665
31142841
21282113
30755420
17353931
25283148
22863883
33961781
19615732
24075985
|
BRCA1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
UBC
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
17568776
5220017
|
SUMO2
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
UBC
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
BARD1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12431996
17525341
29367421
27977889
19916563
12732733
10477523
20060929
23680151
8944023
22110403
12951069
23086937
14638690
27239795
29355525
9788437
11925436
11257228
24289923
14647430
19176389
15184379
9738006
16403807
29180510
11278247
33589814
15265711
15159397
34408138
16713569
19117993
20681793
16391231
11301010
16489000
23416467
17664283
15569676
29858377
19369211
18493658
29656893
20351172
28398198
12485996
32347575
19766185
14636569
10026184
12700228
31270457
11573085
11526114
24085845
25823446
33961781
32092106
18936166
28514442
20215511
25184681
26490435
28948225
12890688
12438698
28262780
26831064
9342365
10635334
15855157
11504724
11773071
25252691
9798686
26350354
21901007
24695549
12887909
17873885
11498787
27454289
11927591
24981860
25652403
25634209
|
BRCA2
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9405383
19875419
23935068
14580352
9774970
15937124
11239456
21076401
10551859
16513631
21601571
25585578
12815053
16793542
11477095
26833090
21670257
26145171
18264088
15713648
9811893
12941707
25282148
20729832
26387543
24835992
18429819
15800651
17515903
21399666
18317453
22116401
11313963
33476590
14636569
15897881
15800615
10373512
9523196
9126738
27941124
17541404
12442171
9560268
20729859
12619154
16914443
28765325
17515904
31113933
28757209
15065660
19303847
28168276
19628690
12606939
24013206
24981860
20871615
15671039
22293751
21789034
|
MDM2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
BABAM1
|
SHMT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
BRCC3
|
BRE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
BRCC3
|
SHMT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
BRE
|
FAM175B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
BRE
|
SHMT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
FAM175B
|
SHMT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
BABAM1
|
FAM175B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
BABAM1
|
BRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
RAD51
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
5219969
17541404
|
UBC
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
BRCC3
|
FAM175B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
UBC
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
TP53
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.99
|
0.99
|
mint
|
17139261
5219401
|
MDM2
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
BABAM1
|
BRE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
PARK2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
BARD1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
MDM2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
BABAM1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19261748
19261749
|
BRCA1
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19342239
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
69.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337601
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18448394
18472307
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
19995904
20029420
20081207
20173781
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCA1
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
FAM175A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCA1
|
BRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCA1
|
UIMC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCA1
|
BRCC3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCA1
|
BARD1
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19342239
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
BRCA2
|
â—¼ SHARES_COMPLEX
|
|
|
69.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337601
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18448394
18472307
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
19995904
20029420
20081207
20173781
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
RAD51
|
â—¼ SHARES_COMPLEX
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
FAM175A
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
MDC1
|
BRCA1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
12607003
15279786
15459660
17303408
17660363
18001824
18006705
18087291
18583988
18590585
18678890
7575488
9407949
|
TP53
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
9582019
11295099
18625847
11003642
12802282
16357511
14710355
9619832
19882681
10884389
11384963
11782367
12024039
15735697
12170778
21245169
17993233
12549011
11431698
16229810
18208621
10597265
21742769
|
UIMC1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17525341
17525342
17525340
17621610
|
BARD1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
99.0
|
1.0
|
Omnipath
|
16403807
16391231
28262780
15159397
25652403
26350354
26490435
14647430
11927591
25184681
16713569
11526114
35203293
9738006
12732733
24289923
11573085
18936166
23086937
24085845
12890688
15855157
24695549
19369211
9798686
11257228
11498787
12700228
11925436
10477523
19176389
23680151
25634209
23416467
34726323
29355525
18369654
14636569
11504724
12951069
19117993
20060929
17873885
14638690
18493658
11278247
15184379
22110403
11301010
11773071
12431996
10635334
20029420
9788437
17664283
21901007
25252691
12485996
10026184
12438698
17525341
16489000
8944023
15265711
12419249
20681793
9342365
27239795
20215511
25823446
19916563
|
MDC1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
18087291
17525332
12607005
|
BRCA2
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA2
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA2
|
RAD51
|
â—¼ SHARES_COMPLEX
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA2
|
BARD1
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
TP53
|
BRCA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9619832
11295099
18765668
12591928
|
BRCA2
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
87.0
|
1.0
|
Omnipath
|
17145710
21601571
15937124
17541404
11313963
16914443
26145171
21670257
18264088
19303847
25585578
12815053
16793542
21789034
25282148
17515904
9126738
20729859
15703751
21076401
15065660
22293751
19875419
12606939
22116401
12619154
23935068
15800615
33476590
15800651
15671039
11477095
16513631
9811893
10551859
20729832
9523196
14636569
17515903
12442171
9405383
26833090
21399666
19628690
9560268
10373512
14580352
|
BARD1
|
BRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCC3
|
FAM175A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCC3
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BARD1
|
BRCC3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCC3
|
FAM175A
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCC3
|
UIMC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
TP53
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
20190820
18359760
9664135
10029407
8152794
11713584
8887630
9285564
19597475
11546792
1586628
18604200
18391986
|
TP53
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
201.0
|
1.0
|
Omnipath
|
23150757
20948295
10871862
10914734
21422812
21957016
14532965
22290440
20663877
20547751
11591713
24339722
11840331
22223137
16492744
15843377
22948151
7888679
20156675
21217645
22180176
8319905
9707425
15831521
17690113
9649502
10688649
9194564
15917661
15090541
20837136
8187772
10788589
17907153
15192123
8440237
11964305
16510138
10856296
15580300
7624148
12208736
21211512
16624812
17848574
11245471
21637567
20588255
10562557
9525742
9270029
16479015
19941079
14602726
15024021
18814047
20036872
10718212
18852133
12374749
18397889
25016801
12755686
22081073
22245141
23365201
8957072
22197810
15856024
20703075
23483203
9645455
19648117
20331637
22301280
14743206
23982177
9486848
15734740
19638633
19671680
17310983
10469568
20659896
10072445
21097889
17237821
11748232
11085543
21750655
16337599
21295542
1614537
9815889
9070662
16585169
9472631
17936559
17139261
11328884
12887889
20858413
9858609
14610316
20080970
19505873
11313463
15684615
18359851
18783169
16202543
9267820
12235242
14990790
15851483
7587074
18336191
21478269
17043642
15361831
18025460
23612020
10208414
11756653
24389645
9071998
9430645
9400998
9371494
23149414
22532570
9271120
10777217
22383580
18781178
12606552
14514686
17318220
11127813
16571800
19085961
9207798
10891494
10065155
11593391
14570892
12902982
19649205
20124454
17390010
19955655
12138177
19663772
23581014
15908423
10321740
23150759
19837670
10348346
18632610
9294611
11956627
12750288
12851404
8313378
9135153
15735665
7958853
8247544
9535786
16501602
18566224
8910340
11046142
9405685
7936649
12173040
17329361
21451571
14704432
23874713
18333294
19541936
22787160
18585004
22085928
12080472
7651818
11179471
10949923
19428175
15592502
8413278
11714701
10566557
18583933
9681831
15550242
15007388
19590512
|
MDM2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
559.0
|
1.0
|
Omnipath
|
20657550
30005830
17616658
9529249
10321734
33650658
9724739
24462112
24621507
15933712
23826318
24667498
22948151
22653443
23776060
25313037
25241761
19303885
16857591
23246961
19033382
20591651
21149449
25417702
15122315
16579792
27543608
29670376
12208736
17848574
26673821
25277184
23443559
23318437
21060154
15210108
19805293
8875929
8058315
21471462
17879958
25362358
23169665
22301280
21584881
20124408
10980696
26876197
17310983
17380154
15058298
24567357
18665269
30109812
25637791
18467333
22337874
22227409
22389628
15242646
22510990
15950904
15001357
19483087
26540344
14559824
21986495
26556313
20708156
19901969
33765973
32528731
11562347
10202144
22374672
10722742
22083959
21965653
17098746
19234109
30679555
16107876
12690203
22525275
19071110
28542145
12620407
20837658
27129163
9131587
24240685
27031960
10681559
19305137
11744695
19188367
16023600
24659749
17347673
12944468
20395212
22084066
20639885
21454483
12897156
16432196
10347217
10706102
11178989
20174603
16751805
15542844
12842086
11431470
11384992
25739118
15064742
23402884
27462439
16905769
22124327
27215386
12867035
22588298
27336364
14702041
16152627
23776465
22262183
21132010
19411846
18309296
23483203
11709713
18981217
14612427
22920093
23671280
24980433
27905468
25168242
21750659
26238070
22737255
23609977
27282385
20847049
20705607
21075307
28082682
17297477
11697899
17936559
24361594
19098711
15469934
34591612
24998844
16212962
11094089
12915590
17116689
11713288
15144954
23201157
10608892
17591690
25156994
17301054
22444248
26883110
26001071
19160491
22157679
24413661
19357310
23802716
15280377
21317885
11597128
19579266
25624478
18061646
21088494
9223638
10435614
31177307
11331603
22391559
20570896
19941302
9278461
18485870
15604276
18566590
12612087
11046142
14704432
26186194
10935507
16173922
14596917
17159902
25543083
19656744
15848166
18316739
22266868
17056014
19255450
21561866
19590512
11839577
22991965
22266850
24200963
11285227
11713287
22975381
19081178
20660730
26475964
16678796
23261415
20173098
17666403
25464845
32427887
23252402
17438265
20959462
22659184
17470788
22912717
17080083
15247280
19332559
17989425
16870621
18813780
20235143
11278372
10562557
25609649
10561590
19411066
17908790
19568783
7926727
21925390
21988832
24127580
18604177
14499615
17371838
17525743
33061576
21887275
26578655
21084564
16861890
20694676
12552135
22914926
17363365
24643130
1614537
22916255
12381304
34992144
12167711
19857530
15053879
10889512
11486026
22103682
16713569
17110336
17426254
10640350
21316347
21478269
15154850
12529318
16595680
16414131
19597489
23880345
27893708
7686617
27811966
17318220
29997244
27308622
19166840
35044719
16159876
24314634
15313915
25283148
22032989
24926618
18172499
19837670
16215989
23134341
26908445
9824166
18451149
21170087
23572512
21465263
22807444
15013777
16845383
10488081
23946421
11714701
25384516
22474335
25312347
23370271
23150757
18541670
22318540
11925449
21572037
24488098
32066565
17268548
20542919
11572869
16338390
21857681
23150668
19223463
20234175
20484049
11070080
20591429
22575647
11351297
16624812
22411991
20588255
17369817
11223036
15908921
9582019
25103245
17302414
21071676
9450543
31968249
34562520
18332869
14671306
21084285
27856536
30464405
26882543
21726810
33020477
21261729
21268072
12426395
16964247
20659896
19106616
22331460
23728348
10827196
22524527
21098709
9363941
17139261
20080206
14517261
22487680
31652301
17290220
27106262
16866370
24207125
28223335
9271120
15550400
7689721
26350565
10196247
27807478
10766163
15558054
35371302
26203195
29487367
25512388
25954860
18223694
15824742
24842904
14741215
16055726
22085928
32894144
18234963
17875722
18815136
15295102
15308643
15358376
22819825
15094782
|
RAD51
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
RAD51
|
BARD1
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
TP53
|
RAD51
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17513613
16322760
20802511
16398215
18769160
|
TP53
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
8617246
11002423
16713569
16322760
16983346
9380510
|
TP53
|
FAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
10101800
12788915
15580300
16317104
16322229
14719118
16557594
20797428
11103825
19615968
7539102
12447615
12944915
12963547
11313989
16951143
9841917
|
UBE2D1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15169778
15340381
15147722
12820959
10722742
19459846
18006823
10721693
19440234
|
BARD1
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
FAM175A
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
FAM175A
|
UIMC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BARD1
|
UIMC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BARD1
|
FAM175A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BARD1
|
FAM175A
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|