Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CLU APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TLR4 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17126326 5219377
TLR2 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17126326 5219377
PLCG2 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
EGFR CD59 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
EGFR AGER â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0600362103 16954185
STAT1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10558875 22693070
EGFR PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 1845983
RAF1 KRT18 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15314064 5217163
F2R MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
SRC MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAF1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 20674547 15664191
MAPK1 MAP2K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 23241949 8412360
MAPK1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15778365
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
F2R MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
RAF1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 20674547 15664191
MAPK3 SOS1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
MTOR AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
AKT1 MTOR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17611497 18954143
AKT1 RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20605787
H2BC12L MACROH2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
COL1A2 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9685391 30632962
H2AX H2BC12L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCL2 MMP14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15516694
C1QBP TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
C1QBP IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
F7 F10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29880919 11560488
TFPI F10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 3422166 12787023
F10 F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25769543 35114109
SRC ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 7296071 19903481
VASP ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 1318192
ACTG1 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ACTG1 TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ACTG1 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CFB C3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 809512 279011
C3 CD55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6238120 8786315
CFD C3 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 809512 279011
C3 CPB2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 11939578 4098172
PIK3CA SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
SYK APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SYK PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9720763 10592173
ITGB1 AGER â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ITGB1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TYK2 STAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15261459 23124025
STAT1 CASP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21530491 12198138
STAT1 LY96 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21572044
RPS27 TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
APP PLAU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
F2 PLAU â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10996659 8428004
PLAU PLAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7721771 16189514
TYK2 EIF2AK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23236554 17290288
YWHAQ RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
APP RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAF1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19197339 7014125
CHUK IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 12799363 23430059
CHUK IKBKB â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 12799363 23430059
A2M CSF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CSF2 SOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1465135 8294403
AGER RHOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19944695 7301165
RHOA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SRC RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10592173 23027962
RHOA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15884057 11748077
GJA1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11035005 5213074
SOS1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ADAM17 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0509719103 16641105
SRC F2RL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC F2R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
SRC FCGR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8756631 18083107
SRC F2RL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17474147
MMP14 F12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10930399
MAPK8 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16306447
KLKB1 MMP3 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 3058116 7826345
IKBKB EIF2AK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10848580 16600570
APP NLRP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17349957 17703304
FAU KLK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPL18A F8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RPL10A PIK3R6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC12L RPL23A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LRP1B APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLK6 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AGER APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP CASP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11967258 12191486
APP F12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP F2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPS8 RPS11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FCGR1A PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR3A PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR2A PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
CFB CFH â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1067618 301546
PASK FGA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 21418524 8145255
F8 F2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0801735105 18492805
F2 PROC â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 468991 2538457
F9 F3 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 2040636 2248955
F9 F7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 2040636 2248955
F7 F9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29880919 2248955
F9 F7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2248955 12524220
ELANE F2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10978167
ELANE F5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9242537
A2M KLKB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2579948 6203908
F12 KLKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28966616 3521732
FCGR2A PLCG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7517665 8657103
SERPING1 MASP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10946292 28742139
MASP2 C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11907111 11527969
MASP2 C4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17204478 22949645
C5 CPB2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 11939578 4098172
C6 C7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17900710 10696521
CFD CFB â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 809512 279011
CFI C4BPB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 293746 702059
BDKRB2 AGTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
AGTR1 YWHAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
IGHG1 FCGR3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1314888 2474607
C4BPA CFI â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 293746 702059
FCGR1A PLCG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7517665 8657103
CFI CR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6214588 1386357
F2RL2 F2R â—¼   PROXIMITY 2.0 0.8 intact 17376866 0700763104
CTSG F2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10978167
C4A CD46 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12055245 2481448
CFI CD46 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6214588 1386357
MMP13 F12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10930399
CD55 C4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6238120 8786315
CFI C4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 293746 702059
CTSG SERPIND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 2318847
H2BC12L FERMT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PLA2G4F H2BC12L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC12L H2AZ2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
C8B C8G â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
F2 FGB â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
F2 FGG â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
MAPK8 MAPK9 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
MYD88 TLR2 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
C8B C9 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
EGFR ACTB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22366308 31980649
C3 CFD â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
AKT3 AKT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RHOA MAPK8 â—¼   PHYSICAL_INTERACTION ✅ + 0.82 0.82 Signor 8824197
ARHGEF1 RHOA â—¼   GTPASE_REACTION ✅ + 0.82 0.82 Signor 10836144
EGFR STAT5B â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 11751923
C1R C1QA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 2372546 10878362
CR2 CR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 1708808 7690834
C3 CFHR4 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
C3 CR2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
C3 ITGAM â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
F2 PROC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CFHR1 C3 â—¼   PHYSICAL_INTERACTION ✅ + 0.83 0.83 Signor 27814381
IKBKB SRC â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
STAT1 MTOR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19553685 25241761 12807916
C1QC C1QB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21054788 16189514 12960167 28325905
STAT1 SRC â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9344858 16189514 14978237 10358079
APP PRNP â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
MAPK1 RAF1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
APP F11 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
HDAC3 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29523594 20026773
AKT2 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 12149249 9736715 12176337 11445557 33961781 14500673 11278835 11546794
BTK PLCG2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11507089 12093870 17290227 10981967
C8A C8B â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
C8A C8G â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
C1QBP F12 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
C1QBP C1QA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34804054 28018340 8195709
ARHGAP35 RHOA â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
APP KLK6 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
FCGR2A SYK â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
EGFR RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
MMP14 C1QBP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12220632 16713569 11773076
SOX2 HDAC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 21532573 23667531
APP CLU â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CFH CFI â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AKT1 CHUK â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EGFR STAT1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
AKT1 RAF1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
AKT1 PIK3CA â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
TLR2 EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17126326 24658140 25402006 31980649
EGFR AKT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
C1QB C1QA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14681455 21054788 12960167
MYD88 TLR2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17126326 15107846 16482509 16293622 29990310
F2 F5 â—¼   UP_REGULATES ✅ + 0.89 0.89 Signor 29880919
ARHGAP35 RHOA â—¼   GTPASE_REACTION ✅ - 0.89 0.89 Signor 32203420
RPL36AL RPS27 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
SRC EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 17284441 6169640
EGFR RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
PLCG2 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 31980649 22973453 24658140 16273093 25402006
EGFR STAT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24797263 31980649 23956138 11294897 15322115 24658140 12637327 7690989 15284024 10918587 25402006 7543024 12070153 12817007 10358079 7657660 11839738
MAPK1 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
RHOA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MAPK1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18378670 7569900 14963018
MAPK3 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
RHOA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MTOR AKT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 18566587 25792870 15718470 14970221 24670654 10910062 18505677 29567957 22337773 21177249 26293922 19299511 18566586 30639242 21045808 11438723 22084251 23872070 21343617 22307628
H2AX ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
F10 F3 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 3527261 3275472 6980899
F8 F10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9759621 10521497 12426309
C1R C1QA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QC C1QA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14681455 21054788 12960167 28325905
C1QA C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C1QA C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C3 CFI â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6607952 21788512 2971659
CTSG C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315997 1861080
C1R C1QC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QC C1S â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QC C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C1QC C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1R C1QB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QB C1S â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QB C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1QB C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
FCGR3A SYK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 7517665 8657103 15161916
IGHG1 SYK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 7517665 8657103 15161916
PLAU ITGB1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 18633355 22470492 27216177
AKT1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16256741 10896934
SRC ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 11723131 11259684
STAT1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18370868 15057743 2606351
STAT1 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19508864 9841227
STAT1 MYD88 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18024894 7567467
MAPK9 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14963018
PLAU HRG â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 2521625 2935528 1829461
IL12A TYK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18389480 7638186 7528775
AKT1 RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 25241761 28628118 10576742 19197339 19058874 28205554
SRC RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17097642 16189514 7517401 8876196 10205168
RHOA ARHGAP35 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18829532 9407060 16308318
ARHGAP35 RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 12429740 16707504
ARHGAP35 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 10592173 32203420
AKT3 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19609947
RHOA ARHGEF12 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
FGG SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGB SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGA SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
PPP1CC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14633703
FGB ITGB3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
ADAM17 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9774383 12535668
RAC2 PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7744773 8645157 11803464
PIK3CA SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21653832 16456001 10068651
C1S C1R â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31749804 10092586 2387866 9477945 33961781 10878362 2372546 12788922 17996945
C1S C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1R C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C1R C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
CFH CFI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26806831 9291131 1401896
GNA13 ARHGEF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11313914 15951850 22661716
FGA APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
F2RL2 F2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 873923 8615752 10079109
F2RL2 F2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 9618465 9087410 1672265
F2 F2RL3 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 9618465 9087410 1672265
F2 F13A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9546612
F2 F8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18492805 10350471
FGB ITGA2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGB APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
F9 F11 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 29223926 22961984 11342438
PROC F8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 1939075 1761551 16189514
ELANE SERPIND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2318847
CASP4 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12843244 9491891 9039262
KLKB1 SERPING1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 3756141 2579948 4178758
IGHG1 FCGR2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7718892 2529342 7521687
MASP2 C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
MASP2 C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C5 C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1387399 2808363
C8A C9 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
C8A C9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10346902 3624872 4063341
FGG APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
IGHG1 PLCG2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
IGHG1 C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
IGHG1 C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
FCGR3A PLCG2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
C4A CR1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10531307 11694537 293688
CFI CR1 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6607952 21788512 2971659
F12 SERPING1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 3756141 4703226 2578463
MMP12 F12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10930399
STAT5B FCGR1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8695838 10820245
EGFR PLCG2 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
EGFR SOS1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
AKT1 MTOR â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
RAF1 YWHAQ â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
C1QB C1QC â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
ARHGEF12 RHOA â—¼   GTPASE_REACTION ✅ + 0.91 0.91 Signor 11094164
MYD88 TLR4 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
MTOR AKT1 â—¼   PHOSPHORYLATION ✅ + 0.92 0.92 Signor 21592956
RPL10A RPL36AL â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
C3 VSIG4 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
RPS27 RPS3 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CFH CFHR1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
F2 F2R â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
FAU RPL36AL â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
RHOA ROCK1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
F2 SERPIND1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
RPL39 RPS3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ACE RHOA â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
FAU RPL22L1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
C6 C8G â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
C6 C8B â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
C6 C9 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
C6 C8A â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
C6 C7 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
F2 F2RL2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
F2 F2RL3 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
FAU RPS3 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
C3 CR1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
RPL39 RPS27 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPL37A RPS27 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
C5 C8G â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
SOS1 EGFR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 24797263 16713569 26005835 9447973 23956138 19531499 7510700 20473329 19289468 25754235 18271526 31959764 10675333 8621459
RAF1 MAP2K1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 7014125 19197339
C1QA C1QC â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
F2 FGA â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
C5 C8A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
C5 C9 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
MAP2K1 MAPK3 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
FGB FGG â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
RPS26 RPS27 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
RPS12 RPS27 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
C1QA C1QB â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
SRC EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 8845374 21573184 25402006 7506422 10075741 19704002 10971656 23175185 10777553 22227249 20935677 20624308 21268077 17158602 24189400 9020193 16713569 22973453 11983694 24658140 28065597 21278788 17284441 7797556 20333651 7527393 10358079
TLR4 MYD88 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17126326 15107846 10952994 17258210 18221795 20048342 15728506 33052227 12646618 11743586 21911421 21829704
LY96 TLR4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10359581 22532668 19060881 15728506 22474354 11976338 17803912 20547845 19252480
ROCK1 RHOA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21281639 31431478 8816443 14660612 12773565 8798490 31871319
MAP2K1 RAF1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
C1R C1S â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
C3 CFHR1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
C5 C6 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MAP2K1 MAPK1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
C3 CD46 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
C5 C7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
C3 CFI â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
RPL27 RPS3 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RPL13A RPS3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
C3 CFB â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
C5 C8B â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
RPL13A RPS27 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
F3 F7 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ARHGEF12 RHOA â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
RPS18 RPS3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
C3 CFH â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
LY96 TLR4 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPL18A RPS27 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPL4 RPS27 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPL12 RPS27 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPL27 RPS27 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPS11 RPS27 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPS2 RPS27 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPS12 RPS3 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPL22 RPS27 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPL10A RPS27 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPL23A RPS27 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPL7A RPS27 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPS18 RPS27 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPS13 RPS27 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPS27 RPS4X â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPS27 RPS8 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPL10A RPS3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL12 RPS3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL37A RPS3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPS11 RPS3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
ITGA2B ITGB3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
FGA FGB â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
FGA FGG â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL23A RPS3 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RPL22 RPS3 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
FAU RPL13A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL13A RPL39 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL4 RPS3 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL18A RPS3 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL39 RPS26 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
FAU RPL22 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL22 RPL39 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
FAU RPL39 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
FAU RPS11 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
FAU RPL4 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
FAU RPL18A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
FAU RPL10A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
FAU RPL7A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
FAU RPS8 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
FAU RPL37A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
FAU RPL27 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL18A RPL39 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL39 RPL4 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL12 RPL39 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL10A RPL39 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL23A RPL39 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL27 RPL39 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL39 RPS8 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL39 RPS12 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL39 RPS23 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL39 RPS13 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL39 RPS2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL39 RPS11 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL39 RPL7A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPS23 RPS27 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPS26 RPS3 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
RPL7A RPS3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
FAU RPS4X â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
FAU RPS18 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
FAU RPS27 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL39 RPS4X â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RPL39 RPS18 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RPS2 RPS3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS23 RPS3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS13 RPS3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS3 RPS4X â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS3 RPS8 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPL37A RPL39 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FAU RPL12 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPL10A RPL13A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL12 RPL13A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPL27 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPS4X â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPL37A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPS26 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPL4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPS18 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPL7A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPS13 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPS8 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPL23A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPS2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPS11 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
FAU RPS26 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL22 RPL27 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
FAU RPS12 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
FAU RPS2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
FAU RPL23A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL18A RPS18 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL18A RPL27 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL4 RPS18 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL12 RPS18 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL10A RPL27 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL10A RPS18 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23A RPL27 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23A RPS18 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL37A RPS18 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL27 RPS18 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL27 RPS11 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPS11 RPS18 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPS23 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL13A RPS12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL13A RPL18A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL13A RPL22 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS18 RPS26 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL22 RPS12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL22 RPS18 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
FAU RPS13 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
FAU RPS23 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL23A RPS12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL27 RPL37A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL37A RPS2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL27 RPS12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL27 RPL7A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS12 RPS18 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS18 RPS23 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS18 RPS2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL7A RPS18 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS13 RPS18 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS18 RPS8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL37A RPS26 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS26 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS26 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS23 RPS26 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS26 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPS26 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPS26 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL27 RPS26 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPS26 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS26 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS26 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPL22 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL22 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPL22 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPL37A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPS23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPL4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPL23A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPL18A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPS23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPS12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL27 RPL4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPL4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPL4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPS23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPL23A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPL37A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPL27 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPS12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL23A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL37A RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL37A RPS12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL37A RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL37A RPS23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL37A RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL37A RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL27 RPS23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL27 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL27 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL27 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL27 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS12 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS12 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS12 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS11 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS11 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS11 RPS23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS13 RPS23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS23 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS2 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS18 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS2 RPS26 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS12 RPS26 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS13 RPS26 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS11 RPS26 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS26 RPS4X â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL10A RPL18A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL18A RPL7A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL18A RPL37A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL18A RPL23A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL18A RPL4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL37A RPL4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL10A RPL37A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL23A RPL37A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL23A RPS2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL37A RPL7A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS11 RPS12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS12 RPS23 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS12 RPS4X â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS11 RPS2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS11 RPS4X â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS2 RPS23 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS23 RPS4X â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS13 RPS2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS2 RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS13 RPS4X â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS13 RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS4X RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
COL1A1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7716514 10464311 7688313
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
MAPK3 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 1651322 17081983 3138233 15901825 16785992 1939237 91332050 27531070 17570479 2543683 2115882 34086370 17192257 1651323 15302935
EGFR STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10830280 10358079 12411494 10558875 16729043 17016520 11751923
EGFR PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 31980649 25241761 16273093 24658140 17570479 25402006
EGFR SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9544989 19531499 9447973 16713569 12577067
EGFR STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 23956138 12070153 11839738 10918587 11447289 11997436 14967450 25402006 12040186 24797263 15173823 7543024 15322115 10358079 6321473 11294897 7690989 10982844 19568798 12637327 14585353 15199124 17496910 11438544 10748192 24658140 7657660 12817007 31980649 22693070 9355737 19615955 11152457 15284024 15567848 7592750 16488589
EGFR MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12556561 15531749
RAF1 MAPK1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
MAP2K1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 149.0 1.0 Omnipath 21675959 9694850 17081983 10757792 11319218 18799465 15592455 12788955 19415658 12697810 17389395 9447970 15342917 8226933 15851026 12270934 12644307 17255949 10998418 11242034 1378617 1381507 17906627 11986622 8376945 8157000 7992057 11948414 9731057 19651622 11251083 11266467 18707149 14743221 11279118 11704645 12750173 12932319 16497976 11337027 23331499 12048245 7559390 17272394 15811950 19494114 18669648 18691976 11741894 15972258 19053285 16094384 17192257 7898932 24623782 9166761 19369195 21336309 12920017 15466214 17016520 19901323 1712480 19690332 11823456 9032297 11134045 12876277 19534553 10995751 20068231 21506533 8223433 8248196 16153436 12594221 10567369 19933846 17563371 11730323 29175850 11352917 16135787 15951569 19058874 15212693 23241949 9560161 91184134 18083107 16887817 18578522 17569879 21071413 9148935 18452278 1330321 8670897 19541618 10777511 15935618 12925710 11971971 9765155 11136732 11118451 12082107 12952943 10746662 21768338
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 GJA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 22028470 9535909 19664994 9535905 12637502 15605363 8631994 17570479
MAPK1 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15994958 11278789 12917630
MAPK1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 17081983 18767875 15849194 19690332 11409918 14654779 23331499 23180781 8226933 20068231 18988627 21917714 18669648 19541618 18691976 16407412 19933846 9922370 15664191 8388392 19651622 10801873 8349614 18775330 9604935
MAPK1 EIF2AK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17404396 9528799
MAPK1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 10197981 8816480 9922370 8626428
MAPK1 RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15950189 22028470
MAPK1 STIM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 25562429 22298426 23687376 24114840 19881501 33023909 25447552 28935720
RAF1 MAPK3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
MAP2K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 9694850 17081983 11319218 18799465 17389395 9447970 15342917 8226933 15851026 12270934 12644307 11242034 1381507 17906627 9677429 11986622 8376945 7992057 11948414 7687743 9731057 19197339 11704645 7565670 12750173 12932319 8626767 23331499 12048245 7559390 17272394 15811950 26987942 19494114 18669648 18691976 17192257 8388392 7898932 16464493 19369195 12920017 15466214 19690332 11134045 19534553 10995751 7867743 8223433 8248196 10567369 19933846 17563371 1518847 11730323 18983981 16186792 16135787 15951569 19058874 15212693 10748187 9560161 9925641 9733512 18083107 11104681 9006895 17569879 21071413 7731720 1330321 93330262 19541618 15466476 12925710 11971971 11136732 11118451 10746662
MAPK3 GJA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 9535909 19664994 9535905 12637502 15605363 8631994 17570479
MAPK3 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15994958 11278789 12917630
MAPK3 RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20041225 15950189 21738525
MAPK3 ADAM17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12058067 18187448 21570469
MAPK3 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 29145629 7478566 23331499 8816480 7739560 17570479 9922370
MAPK3 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 14654779 23331499 19541618 18691976 16407412 19933846 9446616 9922370 15664191 18988627
MTOR AKT1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CHUK MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18519641 24990947 18490760 27027448
MTOR AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20338882 17517883 18372248 19203586 27418134 17277771 15718470 26491696
MTOR AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17517883 18372248 19203586 17277771 15718470
MTOR AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 18000759 20027184 21157483 11756412 11923280 24670654 16697215 11438723 21592956 20398329 17461779 18372248 21177249 21045808 20338997 15808505 16221682 20138985 20489726 15899889 20214616 8978681 21474067 14970221 19203586 17660512 15718470 19568798 20333297 23006971 15169778 25241761 18566586 19720745 17517883 18925875 22084251 10949026 14761976 11715018 19143635 17277771 18636226 10910062 15047712 9812896 18505677 21343617 19844585 17680028 19151919 18566587 9736715 23872070 10722653 20832730 18570873 17013611 17052453 12408816 15364915 11274345
COL1A2 ITGA2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11359786
COL1A2 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1693626
MAPK8 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 22972376 16818236 19234442 17211821
MAPK9 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16818236 19234442 18158901
FCER1G SYK â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12731048 15081523 15099567 20814939 23414611 2451784 7590867 9625766 9952373
FCER1G SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9280292 17145710 8071371 8810294 8663460
MYD88 CCL2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
LY96 CCL2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
STAT1 CCL2 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17255531 19915063 17167270 7561042 9558097 19404962
KLKB1 C1QBP â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14996700 12123826 11830581 8344943
F12 C1QBP â—¼   CLEAVAGE ✅ 8.0 1.0 Reactome 3886654 874082 11204562 6604055 11986212 1066663 14691562 7391081
C1QBP C1QA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 28018340 8195709 34804054
F8 F10 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 2105717 1958666 2303434 7803238 1346975 26023895 3965513
F9 F10 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 2105717 1958666 2303434 7803238 1346975 26023895 3965513
ACTB RHOA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
RHOA ACTG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
C9 C8G â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
C8G CD59 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
CFI C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16023208 1401896 26806831 9291131 8648130 2141838
CFH C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 16023208 19050261 11367533 21979047 21317894 9988761 16612335
C3 C3AR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8702752 11342658 8765043 20527893 9476119
C3 CR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10382758 2551147 9988761 2141838
C3 ITGAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 4062888 11073102 26293614
FCGR1A SYK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8226994 18818202 8862523 8340414 7522622 7530449 9314552
IGHG1 SYK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8226994 18818202 8862523 8340414 7522622 7530449 9314552
SYK SOS1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
SRC SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7513017 17353363 17570479 16189514 9389695 23100514
SYK FCGR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9280292 9632805 11141335 15136586 8756631 9295288 8663460 9268059
SYK PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771181 19783684 12470302 16449524 14656219 10469124 10933389
SYK BTK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 18083107 8629002 28368423 11598012 28359287 29455639 19369195 10051622 9012831 8630736 28088788 11226282
SYK ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17353363 18088087 11940607 15699036 11042121 8631894 11723131 11719224
FGA ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15031111 7716514
THBS1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15292271
ADAM17 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22413019 14970227 30455686
STAT1 STAT5B â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
CSF2 STAT1 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
TYK2 STAT1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
STAT1 MYD88 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 IL12A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19029990 19164128 21987655 20709027
STAT1 FCGR1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9748323 8830676 8483949 8647290 12130529 14734612 9551929 7995951 16516295 10820245
STAT1 MMP13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10645003 17208315 17179173
STAT1 CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15006601 25199798 22022583 23153456 23740952 9690917 9858321 24127910 12754213 19479051 20585034 20833730 17558387 19136629 28262979
MAPK8 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24913968 14963018
TYK2 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 11839738 10918587 15261459 8232552 7543024 15322115 23331499 8780896 10435617 24243840 11294897 7690989 14764663 18988627 12637327 11438544 10748192 14565860 7657660 12817007 23257612 29145629 9355737 11152457 23124025 18389480 10982844 7592750
EIF2AK2 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23597922 9135145 11278865 16516295 10637230
SRC STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 11839738 10918587 9344858 7543024 15322115 10358079 14978237 11294897 7690989 16189514 12637327 11438544 10748192 7657660 12817007 9355737 11152457 10982844 7592750
STAT1 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17339457 17085014
TLR4 TAB2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 15327770 19675569 16115877 10882101
TAB2 LY96 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 15327770 19675569 16115877 10882101
TAB2 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14960582 15836773 11274345 20194509 18855897
MYD88 LY96 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
MYD88 LY96 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
MYD88 NLRP3 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
MYD88 CXCL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
TLR4 MYD88 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 22664090 19717524 20048342 21911421 9625770 17228323 17258210 11743586 15107846 15728506 12888566 21829704 18221795 10952994 17635639 17126326 12646618
TLR2 MYD88 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 22673208 19717524 22664090 20348427 16893894 15107846 29990310 16798732 16482509 16293622 17126326
TYK2 STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12411494 10830280 9872990 11751923
CYBA CYBB â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBA RAC2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11145705 1660188 18347018 11090627 10455184
CYBA CYBB â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
RAF1 PPP1CC â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
AKT1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 51.0 1.0 Omnipath 19197339 11971957 18767875 20230923 10576742 20068231 17570479 16189514 18669648 25241761 18691976 10576741 10618391 20688159 21745501 12087097 12801936 12048182 22798428 16854453 19058874 11997508
YWHAQ RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 14688280 7760835 17353931 16041367 11697890
SRC RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 7692235 12551923 7517401 17097642 15258589 9689060 16189514 16630891 10998357 11376654 29063113 8876196 10205168 28846113 12952943 22592532 11134016 15710605 16170185
RAF1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 14688280 7760835 17353931 16041367 11697890
RAF1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 143.0 1.0 Omnipath 10757792 18337766 18799465 15342917 23728975 26496610 15866172 17053865 11242034 9351825 9677429 8157000 7992057 11948414 11604401 16129686 10677502 12695496 19197339 7565670 12750173 7936666 1326789 19219045 23331499 18556463 10976102 18988627 15485920 15175348 18691976 16407412 10409742 9311917 17192257 7898932 8621729 23934108 11684694 21336309 7624324 12920017 11948406 15466214 11042690 12907640 9032297 27169363 12876277 8933152 8223433 8248196 8131746 12594221 10969079 10567369 17979178 17724343 24746704 19058874 10958680 8090753 21071413 7731720 7873542 1330321 8503013 16093354 19541618 8394352 15466476 25155755 11136732 9069260 94178255 8607979 10327068 10359597 8039496 20212043
RAC2 ARHGAP35 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7479768 17765681 16777452 27481945 31871319
SRC ARHGAP35 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
ARHGAP35 RHOA â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 17517963 18829532 22411312 8360177 9819392
SRC ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 19901323 21937717 18541700 20068231 9819392 10592173 11309200 16497976 15592455 17570479 16513268 7542246 30664792 17016520 32540970
ROCK1 ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19103606 19673492
HDAC3 CXCL10 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
TLR4 CHUK â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15064760 15814722 16115877 16603398 16547522
CHUK LY96 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15064760 15814722 16115877 16603398 16547522
AKT2 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19609947 12048203 10485710
EIF2AK2 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10723127 10648614
AKT1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 15710601 12048203 25241761 19442713 11278366 10485711 15800029 19609947 17570479 17660512 18515365 19088076 10485710
SRC CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17145710 12707358
CHUK H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12588998 17643371
CHUK IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 91.0 1.0 Omnipath 9346484 24911653 20932476 28514442 11971985 16970925 12210728 9346485 17965022 16713569 12486103 9891086 15456791 11057907 20434986 16129692 16260493 21903422 21724995 16286467 14743216 16319058 18949366 10779355 25748427 25852190 12244103 11585904 9751060 15218526 10094049 10837071 9914500 21575199 9721103 25241761 10195894 9689078 15214841 21784860 17561400 21640763 16285893 10733566 16186825 16493424 10022904 12709429 12351658 10968790 12547194 15691841 15620648 15327770 11864612 11460167 14636585 17693255 17072322 9346241
BTK LY96 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
IKBKB LY96 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15064760 15814722 16115877 16603398 16547522
LY96 NLRP3 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
LY96 CXCL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
LY96 TLR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 12960171 17056597 17803912 11435474 11976338 15175334 16272300 19060881 11160242 22474354 22433852 15557191 11593030 22532668 19252480 17535871 24097189 10359581 15694388 15728506 14607928
TLR4 IKBKB â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15064760 15814722 16115877 16603398 16547522
TLR4 BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
CYBB RAC2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11145705 1660188 18347018 11090627 10455184
THBS1 ITGA2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 2478219
THBS1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 2478219 14963009
RHOA ROCK1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11698448 11729192 11739775 11992112 12194823 12361600 12740575 14657501 14744429 15761148 17517963 18037882 18423981 20535745 21178402 22949611 24857661 24919149 26885855 27048821 27066895 7479854 9362522 9660866 9822605
ARHGEF1 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9789025 12748184 32203420 9113980 9641915 10836144 11149925
ARHGEF12 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9789025 17145710 15364580 23405219 32203420 9113980 9641915 20300064 10592173 11373293 12515866 11094164 11149925
RHOA ROCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 17145710 12361600 25010901 23151663 7479854 27048821 22949611 21281639 26885855 8798490 12727213 17673200 11729192 8816443 10592173 11698448 27066895 11739775 11992112 20535745 18423981 24857661 21178402 23109003 9660866 9822605 17517963 14660612 15774750 12740575 14744429 9535835 12773565 15761148 24919149 26192618 9362522 18037882 14657501 12194823
RHOA MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15659383 25241761 8824197
SRC APBB1IP â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
SRC PIK3CA â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 12682286 15314172 20861220 18657504 11689445 12431978 25587652 11044445 22266855 11029403 11029009
SRC CLEC7A â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 16341139 10779524 20193029 15845454 21525931
SRC PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 30819914 12181444 11606584 14656219 7682059 15144186 11507089
SRC PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12750372 10592173 17275257 10830300
SRC SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17474147 9856337
SRC VCL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 28592633 25115937 15229287 28684609
SRC CDH5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 36.0 1.0 Omnipath 28712573 24525631 26504080 24590762 25675998 25447529 24358106 27381080 20708398 33836597 26905827 24136461 19644057 21123455 24446483 22648953 22897853 24583284 29326721 16909109 33604918 21037229 25924235 28057793 28119542 16027153 26598555 33712448
SRC ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10330414 17473008 8631894 18156175 25694433 18840695 18364349 18398066 10592173 16935858 21956114 17353363 18088087 12359711 15212693 14996908 15695822 15699036 11723131 20702409
SRC BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10085087 16226010
SRC IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 12645577 12707358 15456896
SRC GJA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 24508467 19901323 16492141 21856279 10871288 11514593 10679481 15782139 9592087 16189514 30448479 30095367 19284610 26706150 30323740 27280719 9278444 24670366 15350848 16916748 23718910 22342665 15534005 29587860 23596415
SRC STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19438593 12429742 17997837 12621061
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
SRC BTK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19109164 23170196 8629002 29455639 10051622 8630736 26165234 9052864
PIK3CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25793261 19117013 21041639 24950409 21816939
AKT1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18578522 10896934
AKT1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11546794 14500673 12176337 11445557 9736715 12149249 11278835
AKT1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15184909 25241761 22689577 15856005 10485711 17660512
AKT1 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12588998 12529330
AKT1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
ITGB3 APBB1IP â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
PRKG1 VASP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 10922374 20058876 8182057 15694326 20166139 14679200 7925440 23867907 94237860 20483741 17570479 17287340 9685341 21702043 15066263 15212693 10851246 12576312
GNA13 ARHGEF12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12515866 11094164 12024019
MAPK8 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12917434 14970211 24610780 20122754 15936948
SERPING1 C1S â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9882449 17488724 3756141 28742139 6604523
CFHR1 CFH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 8663389 16189514 27814381 19528535
F2R GNA13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8290554 20223821 10922491 16189514 22318735 22972936 21331223
GNA13 ARHGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14607242 9641916 9641915 16189514 12681510
MAPK8 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15994958 11278789 12917630
PLCG2 SOS1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11390650 20484116 10811803 12471105
FGA BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
F2 FGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25241761 2133223 2742826 1587268
FGA PLAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 3088041 11170397
F8 F2 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 19240027 8052958 2104766 15705787 1851341 2109644 1973901
F2 F11 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F2 F2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9058715 10978167 15707890 10644723 14652070 11356985 23450633 18250335 12563219 22972936
F2 F2RL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1273221212732210 12732212 22318735
F2 F2RL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11356985 12732212 1135698512732210
F2 F5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10026263 9032460 29880919
FGB BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
TLR2 BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
FGG BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
BTK PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 19901323 19690332 15184383 16497976 33419778 34141433 15509800 30344948 12235209 14656219 17290227 12780340 12181444 11606584 21074890 7682059 11507089 15144186 22409342 29455639 17239630 10498607
F12 KLKB1 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 30394658 30591525 27130860 6604055
C5 CD59 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
C5 C5AR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 9881961 11773063 9553099 15661745 10602324 1847994
C9 C8B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
C8B CD59 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
C9 C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
C6 CD59 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
C9 C8A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
ITGA2B APBB1IP â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
F7 F3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 25241761 15664864 8940045 9414278 9925787 15522303 8598903 12787023
PROC F5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10026263 1615482 7989361 29880919
IGHG1 FCGR1A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
ADCY5 CAMP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23109003 15539636 7935349 16460834
F12 F11 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 1998667 588558 893417 10781579
MAPK9 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12917630 15994958 11278789 20068231
C7 CD59 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
CD59 C9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 7523406 1377690
C9 C7 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145