Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CD44 ARHGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12748184 16189514
IL1R2 IL1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16971486 0603545103
IL1A IL1R2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16971486 0603545103
IL1A IL1R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2946959 8327496
LYN PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11598010 12506011
LYN ITGB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7219790 14593208
LYN PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11598010 12506011
F2R MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
SRC MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
PPP1CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
MAPK11 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23602568 21900206
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
F2R MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
PPP1CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
MAPK3 MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15310280 10402467
EPO PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11598010 12506011
FCGR1A PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
DAG1 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 CD19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6730437 7684160
PIK3R1 FLT3LG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19438505 11027663
PIK3R1 PLCG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 GNAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16268778 18515384
PIK3R1 MYLK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FLT3 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 9918857
CD2 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8557753
RAP1B TLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18434644 17624957
ITGA2 COL1A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219911 17485091
COL1A2 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9685391 30632962
COL1A2 ITGA11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30632962 32196115
HOXA1 LAMB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HOXA1 AGRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HOXA1 VWF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HOXA1 FN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HOXA1 LAMA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
NOS3 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17502619 0611416104
SRC ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 7296071 19903481
VASP ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 1318192
GNAI3 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8327893 19703466
SRC ITGB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19910644 10592173
ITGB5 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19910644 10592173
SRC LCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6546918 15929943
LCP2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6546918 15929943
LCP2 FCGR1A â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6548125 9716598
LCP2 PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10469124 16189514
ITGB3 ITGAV â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214491 11546839
TNC ITGAV â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9314546 32196115
FN1 ITGB1 â—¼   COLOCALIZATION 2.0 0.8 intact 21985969 8208414
VTN ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7716514 32196115
FYN CD2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6548030 9677430
SRC FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
GP6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0906436106 19940238
FYN CSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8981370 20489731
FYN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN FLT3LG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7692230 26848862
FYN IL3RA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN CSF1R â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6730431 7681396
FYN PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
GNAS ADCY4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9228084 21406690
GNAS ADCY3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9228084 21406690
IL1R1 IL1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221365 9062193
ZBTB16 IL6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ZBTB16 KIT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17664282 22385656
IL4R IL4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10219247 5211389
CD14 CD36 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16880211 18178856
GATA1 IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15739164 21454593
THBS1 ITGA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11980922 10982388
CSF1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8981370 20489731
ITGA5 FN1 â—¼   COLOCALIZATION 2.0 0.8 intact 16457822 5218313
SRC RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10592173 23027962
RHOA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15884057 11748077
SRC F2R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
SRC FCGR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8756631 18083107
ROCK1 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19306866
CD4 HLA-DRA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQB1 CD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 11535811
PPP1CA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8288823 20186153
PPP1CA AKT1 â—¼   COLOCALIZATION 2.0 0.8 intact 8288823 20186153
PPP1CA AKT1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288823 20186153
COMP ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20033473 32196115
PRKG1 ITPR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18757735 0804738105
FN1 TNR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7499434 7527058
FN1 SDC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23290138 27235146
F2R GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22318735 31160049
F2RL3 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17158345 31160049
GNAI1 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15922020 19703466
HLA-DRA CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
GNAQ PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
GNAQ PLCB2 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
GNAQ PLCB3 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
PLCB2 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
PLCB2 PLCB3 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
EPO PIK3CG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11598010 12506011
EPOR PIK3CG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11598010 12506011
EPOR PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11598010 12506011
EPO PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11598010 12506011
CD3G PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR2A PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR1A PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
VWF GP1BA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215664 12183630
GATA1 GP1BA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17725493 12724402
HLA-DQA1 CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3D CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3D CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3E CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
AGRN DAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30478082 7531888
LAMA5 DAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16709410 10207021
FCGR2A PLCG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7517665 8657103
HLA-DQB1 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11376336 5214072
HLA-DQA1 CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQB1 HLA-DQA1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
EPOR EPO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
EPO PLCG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15644415 8034732
PLCB3 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
MYLK MYL12A â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 8149717 21457715
ZBTB16 IL3RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19723763
FCGR1A PLCG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7517665 8657103
MYLK3 MYL12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17924679 19690332
VWF GP1BB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1939645 2010539
VWF GP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1939645 2010539
VWF GP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1939645 2010539
F2 FGB â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
F2 FGG â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ITGA2 ITGB1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
ITGA5 ITGB3 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
CD44 LAMA3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LYN CD19 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10933394 7589101 15187135 7568175
CSF2 CSF3R â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11468284 9187659
AKT3 AKT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CD3E GP1BB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CD1E STIM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ARHGEF1 RHOA â—¼   GTPASE_REACTION ✅ + 0.82 0.82 Signor 10836144
GNAQ PLCB3 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CSF3 CSF3R â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16492764 10364174
CR2 CR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 1708808 7690834
AKT1 MAPK14 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
DAG1 LAMA5 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
FLT3 FLT3LG â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CD3D CD3G â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
IL1B IL1R2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CD36 FYN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 1715582 7521304 16713569 29269414
CR2 CD19 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9804823 1702139 1383329
HLA-DRB1 HLA-DRA â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5220278 7477400
CSF1R PIK3R1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ITGAV ITGB1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
SRC LYN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 9169421 18070987 22581261
LYN EPOR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9573010
AKT2 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 12149249 9736715 12176337 11445557 33961781 14500673 11278835 11546794
BTK PLCG2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11507089 12093870 17290227 10981967
FCER2 CR2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 7515913 8766552
CD8A CD8B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CD44 CD9 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9117348 26686862
CD24 LYN â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22731636 8753773
ITPR1 AKT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24947355 18250332
GP1BA GP1BB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 18674540 12693941 18789323 9325245
ARHGAP35 RHOA â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
AKT1 NOS3 â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 24379783
GNAI1 GNAI2 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
CD36 LYN â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 1715582 20037584
LYN BTK â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11226282 8058772 11598012 8629002 8630736
FYN PLCG2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 8395016 16189514 16713569 7682059 12181444 15144186
SRC KIT â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24728074 12878163 12444928
LAMA5 LAMC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14681455 11133776 25241761 26344197
LAMC1 LAMB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17517882
GNAI1 GNAI3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
FN1 ITGA5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MAPK1 MAPK14 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HOXA1 SPRY2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CD9 ITGB1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
GP1BA GP9 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ITGB1 TLN1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
FN1 ITGB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
FYN CD44 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9573028 16189514 16713569
CSF1R FYN â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 7681396 16713569
IL1R1 IL1B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 7878046 9062193
RHOA ITPR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 12766172
AKT1 NOS3 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
PPP1CA PPP1CB â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
APPBP2 ITGB5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
GNAI2 GNAI3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
ITGA1 ITGB1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CD3D CD3E â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
GNAS PTGIR â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
GNA13 TBXA2R â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CD44 SRC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21701559 11084024 9519902
LYN PLCG2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8395016 10981967 7682059 12181444 15144186
LYN CD22 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10748054 8647200 10228003
KIT PIK3R1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
CD2 FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 9677430
SRC FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31980649 19711372 9169421 33961781 16966330
DAG1 FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17474147 11724572
IL3RA IL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9278420 7957082 8649415
PLCB1 GNAQ â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16754659 12193606 11753430
PIK3R1 SRC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
ARHGAP35 RHOA â—¼   GTPASE_REACTION ✅ - 0.89 0.89 Signor 32203420
GNAQ TBXA2R â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CD44 TLN1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 22566907 23620508 23886063
LYN KIT â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9341198 11825908 24728074
LYN CD22 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9547345 9601638 9480991
LYN PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10318860
LYN ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11782428
PPP1CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
RHOA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MAPK1 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15967790
MAPK11 MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK3 PPP1CA â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
RHOA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
CD5 PIK3R1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 1830270316 8034685 9079809
PIK3R1 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8596638 14665640 11733063
FGA TLN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
VWF TLN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGG TLN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
TLN1 ITGB7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19118207 12606711
PPP1CB NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19036824
GATA1 FCER1G â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16522818 15967781 24639354
GATA1 KLF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20564185 8195185 18487511
ITGB1 LAMB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGA3 LAMB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGAV COMP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16051604 20033473 15345499
LAMA5 ITGB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGB1 LAMB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGB1 LAMC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGB1 COMP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16051604 20033473 15345499
AKT1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16256741 10896934
CHAD ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9281592
LAMB1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10842354
COL4A1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8223488
SRC ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 11723131 11259684
CD2 CD4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19398758 19494291 26794910
FYN ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18541700 23144976 11536198
GNAS ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690
GNAS ADCY8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
GNAS ADCY9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
GNAS ADCY7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
RHOA ARHGAP35 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18829532 9407060 16308318
ARHGAP35 RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 12429740 16707504
ARHGAP35 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 10592173 32203420
KIT PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17496910 7520444
CSF1R CSF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26235028 2408759 22483114 8355686 22153499 22902366
CSF1 CSF3R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16492764 23331499
CSF1 CSF2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 10572088
COMP CD47 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16051604 20033473 15345499
ITGA5 COMP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16051604 20033473 15345499
RHOA ARHGEF12 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
FGG SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGB SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FN1 SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGA SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
VWF SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
SRC DAG1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17474147 11724572 12795607
SPRY2 SRC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
SRC PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25814554 22402981
COL2A1 ITGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7688313
CHAD ITGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9281592
COL4A1 ITGA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8223488
FGG VTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16189514 2243140 11744726
VWF ITGB3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGB ITGB3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
ITGB3 COMP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16051604 20033473 15345499
FN1 APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FN1 ITGA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9733622
FN1 ITGB8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7542940
CSF3 CSF2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 10572088
ZBTB16 SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LAMB1 ITGA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMC1 ITGA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMA5 ITGA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGA3 LAMA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
HLA-DRA HLA-DQA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
GNAQ BTK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9770463 11742120 9305846
PTGIR GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10446129 31160049 11443126
FGB RAP1B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGA RAP1B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
VWF RAP1B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGG RAP1B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
RAP1B APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17624957 15469846 16757337
PPP1CA NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19036824
GNA13 ARHGEF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11313914 15951850 22661716
GP1BA VWF â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12183630 6336654 15039442 7690774 12087105 2690940
F9 GP1BA â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 29223926 22961984 11342438
FGA APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
F2 F2RL3 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 9618465 9087410 1672265
FGB ITGA2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGB APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGB PIK3R3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
F9 GP1BB â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 29223926 22961984 11342438
F9 GP5 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 29223926 22961984 11342438
F9 GP9 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 29223926 22961984 11342438
LAMA1 DAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11798066 16709410 7925941
COL4A1 ITGB8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7542940
IL5RA IL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7721873 22153509 10823900 7957082 1495999 1732409 10880230
AKT3 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24379783
EPOR EPO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9030560 29997244 9808045 17327410 9774108 26481148 15358619 10318834 8662939
EPOR PLCG2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15953601 15644415
VWF APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGG APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
VWF ITGA2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
GATA1 GP1BB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11418466 8703016
GATA1 GP6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12377757 12359731
GATA1 TBXA2R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18698092
STIM1 ITPR1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 19249086 18596693 18187424
CD3G PLCG2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
AKT2 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24379783
STIM1 ITPR2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 19249086 18596693 18187424
STIM1 ITPR3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 19249086 18596693 18187424
ITGB3 TLN1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
EPO EPOR â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
LAMA5 LAMB1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
ARHGEF12 RHOA â—¼   GTPASE_REACTION ✅ + 0.91 0.91 Signor 11094164
CSF3 CSF3R â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CD3E CD3G â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
F2 F2R â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
F2 GP1BA â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
FN1 ITGAV â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
PIK3CB PIK3R3 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
COL4A1 COL4A2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
RHOA ROCK1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
IL1B IL1R1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
GNAI2 GNAI3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22939629 33961781 26186194
GNAI1 GNAI3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22939629 33961781 26186194
CD3G CD3E â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 20890284 9582308 2138083
LAMA5 DAG1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 10207021 30914516
APBB1IP TLN1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ADCY9 GNAS â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
DAG1 LAMA1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
PIK3CB PIK3R1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
F2 F2RL3 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
F2 FGA â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
HLA-DRA HLA-DRB5 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
HLA-DMB HLA-DRA â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
FGB FGG â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
LAMA5 LAMC1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
ROCK1 RHOA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21281639 31431478 8816443 14660612 12773565 8798490 31871319
LAMB1 LAMC1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
IL5 IL5RA â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
FN1 ITGB3 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
GP1BA VWF â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ARHGEF12 RHOA â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
AGRN DAG1 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
ITGA5 ITGB1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ITGA2B ITGB3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
FGA FGB â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
FGA FGG â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
HLA-DRA HLA-DRB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HLA-DQA1 HLA-DQB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
FN1 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1730778
COL1A1 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1730778 16189514
COL1A2 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1730778
COL1A1 ITGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11359786 7688313 11856343 2156854
COL1A1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7716514 10464311 7688313
COL1A1 ITGA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1693626 16189514
COL1A1 ITGA11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11359786 10464311 7688313 11856343 2156854
IL1A IL1R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 25241761 16971486 7878046 1833184 9862719 23395675 78780467878046
IL1A IL1R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23331499 29469592946959 8142597 19479203 7692435 9565970 7775431 2946959 17507369 7964161
EPO LYN â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 9334184 9974393 9774108 9573010 11231127 2163696
LYN CSF3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8197119 16492764 16720384 7512720 10537111
LYN CSF3R â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8197119 16492764 16720384 7512720 10537111
ITGB1 LYN â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
LYN FCER1G â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12524384 19909365 21910624 24445665 26552706 8064233 8132624 8478617 8892616
GNAI2 LYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 11007482 11160627 10753828 9722546
LYN MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11131153
LYN CD19 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 15187135 10706702 7568175 25673924 7589101 10201980 16497976 10933394 9190913 15212693 11809733
LYN PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 19901323 8395016 12181444 11606584 14656219 7682059 15144186 10469124 11507089 16497976 10981967 15212693
LYN IL5RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11823534
LYN CD22 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 32323266 10228003 8647200 9586639
LYN PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21780115 29145629 12506011 18453587 11526404 10455108 15032589 23109003 23180781 9334184 15149544 10194437 22880054 11598010 10488096
LYN FCGR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8756631 9268059
LYN KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 24728074 11825908 9341198 17570479
LYN EPOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9573010 12441334 10579919
LYN BTK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 18083107 8629002 12573241 11598012 19369195 10051622 9012831 8630736 9730885 10811866 9052864 8058772 11226282
MAPK14 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15187187 21675959 18039929 12738796 11157753 22521293 17255949 11238443 11274345 12697810
MAPK13 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 PLA2G4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 17081983 15547943 19114553 17570479 18280113 21185392 19541618 8381049 19565474 7766652 10978317 18632668 9468497 17178906 8636128 11737068 32559461 18775330 12576304 12885780 15212693
MAPK1 PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11287604 11481231
MAPK1 STIM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 25562429 22298426 23687376 24114840 19881501 33023909 25447552 28935720
FYN MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15735648
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK14 PLA2G4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8636128 20068231 10978317 9468497 8910365
MAPK11 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK13 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK3 PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11287604 11481231
MAPK3 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15967790
MAPK3 PLA2G4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8636128 17081983 19541618 8381049 19565474 18775330 9468497 15547943 19114553 10978317 17178906
CD19 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7684160 10201980 7528218 25673924
KIT PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9092574 17496910 1382595 11071635 25241761 24728074 7509796 7537096 12878163 10022833 16713569 7520444 17452978 9233773
EPOR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 7559499 15644415 16713569 24113870 9162069
CD3E PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9312149 11855827 11689561
IL7R PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9233603 7522165
FYN PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8294442 8394019 7515100 17570479 16713569 7520528 1652056
IL1R1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 9360994 10373529
PIK3R1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10527852 16799564 19442713
PIK3R1 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8596638 25241761 20713702 27107012 11733063 21825134 32814053 26496610 8139559 14729945 10358930 14665640
PIK3R1 PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17474147 25241761
ITGA2B TLN1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
TLN1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19118207 12606711 7716514 3124107 10497223 19118212 21947080 11279249
TLN1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19118207 12606711 17218263 35044719 11932255 10497223 9065427 18156175 32196115 12535520 20739287 16546176
TLN1 ITGB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19118207 22025551 12606711 32196115
FCER1G TNF â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12731048 15081523 15099567 20814939 23414611 2451784 7590867 9625766 9952373
IL6 TNF â—¼   DOWN_REGULATES ✅ - 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
IL6R TNF â—¼   DOWN_REGULATES ✅ - 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
COL1A2 ITGA2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11359786
COL1A2 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1693626
COL1A2 ITGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 2156854 17485091
RHOA PPP1CB â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
PPP1CB ROCK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
PPP1CB AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20186153 14633703
FYN FCER1G â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10591186 10648627 11062502 12218089 12731048 15536084 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
FCER1G IL6 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12731048 15081523 15099567 20814939 23414611 2451784 7590867 9625766 9952373
ACTB RHOA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
GNAI3 ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933 8327893
GNAI3 ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
RHOA ACTG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
ITGAV ITGB5 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
ITGAV ITGB5 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
ITGB5 ITGA2 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 22470492 24309651 26519775 9295024 9763615
ITGB5 ITGA1 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 22470492 24309651 26519775 9295024 9763615
FN1 ITGB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1694173 1532572 17015452 18480047
PLCG2 LCP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11390650 20484116 10811803 12471105
FYN LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10648627 9047237
VTN ITGAV â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 7525578 7559467 17968485 9251239 7685013 9443892
ITGAV ITGB3 â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
ITGAV ITGB3 â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
FN1 ITGAV â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 1694173 18480047 1532572 19738201 23154389 17015452
COL4A1 ITGAV â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14610079
VTN ITGAV â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23154389
VTN ITGB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 2412224 2420006 7685013 7542669
ITGB1 ITGA5 â—¼   PHYSICAL_INTERACTION 29.0 1.0 ACSN 10461188 10545505 10559936 10613909 11340065 11413130 11950587 12731048 15866889 16076871 16919435 17522712 18037882 19161977 19339212 19454690 19487819 20644254 20814939 22067905 22154077 22470492 24202395 7529872 7657702 9003039 9456329 9763606 9973479
ITGB1 FN1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGB1 ITGA5 â—¼   PROTEIN_INTERACTION 29.0 1.0 ACSN 10461188 10545505 10559936 10613909 11340065 11413130 11950587 12731048 15866889 16076871 16919435 17522712 18037882 19161977 19339212 19454690 19487819 20644254 20814939 22067905 22154077 22470492 24202395 7529872 7657702 9003039 9456329 9763606 9973479
ITGB1 FN1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGB1 FN1 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGB1 FYN â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
FGA ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15031111 7716514
THBS1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15292271
THBS2 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15292271
TNC ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14715956
COL2A1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9685391 7688313
FN1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9842903 22451694 17015452 18480047 19738201 7688313 1694173 6325925 25237190 26456826 10772816 7626807 21985969 6284125 1532572 11010812 8120056
CD59 CD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16189514 1385156 1377404
FN1 FYN â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
CD36 FYN â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10358164 11907067 12524384 14568985 15536084 17101731 19909365 20150200015 21149606 21378271 21910624 23609447 8189062 8226994 9000133 9295024 9314552 9396765 9632805 9763615
ITGA5 FYN â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
IL7R FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7515933 16713569
FYN KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9038210 9799234 12374739
FYN CD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12522270 11298344 11751967 15144186 26363459 15659558
FYN PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19901323 8395016 12181444 11606584 14656219 7682059 15144186 11507089 16497976 16713569
FYN ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 14761954 28598420 18056410 8633244
FYN FCGR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8756631
GNAS ADCY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9228084 9395396 1719547 9268375 21406690
GNAS ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9228084 6935665 210183 17652154 2022671 21406690 32196115
GNAS ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9228084 9748257 9268375 21406690
IL1B IL1R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 17145710 23331499 8142597 9062193 7878046 9820540 7775431 2946959 24166242 9625767
IL6 IL6R â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
IL6 IL6R â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
CD14 IL6 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IL6 IL6R â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
IL6 IL6R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 17145710 8702737 7744001 23663276 15895091 9028955 1995637 23331499 12829785 3136546 21071413 14656210 28265003 12643274 7893704 18923185 11238858 8706672 8676083 18067990 2788034 14557255 18775332 9694899 7744875
FN1 ITGB7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1372909
SRC ARHGAP35 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
ARHGAP35 RHOA â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 17517963 18829532 22411312 8360177 9819392
SRC ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 19901323 21937717 18541700 20068231 9819392 10592173 11309200 16497976 15592455 17570479 16513268 7542246 30664792 17016520 32540970
ROCK1 ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19103606 19673492
GATA1 KIT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27858941 20405120 9345037 16024808
SRC KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12878163 7520444 10523831
IL4 IL4R â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10358772 10485906 10856136 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21115385 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 7543512 9834059
IL4 IL4R â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10358772 10485906 10856136 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21115385 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 7543512 9834059
CSF2 IL4R â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10426994 11015446 11280761 11460167 11777960 11907067 12193690 12907458 14660645 15536084 16713974 17301840 18264787 20805416 21133840 21232017 21765015 22869907 24030977 24699077 24958845
IL4 IL4R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 11786020 17145710 18852293 23597562 23331499 12704343 8639787 2307934 7918378 21889455 10219247 17312100 8266078 11815609 10850446 18243101 2278997 791837811786020 9874253 7721786
CD14 ITGAM â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10201950 16751103 3537192 2462607
CD14 BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
CD14 FLT3 â—¼   DOWN_REGULATES ✅ - 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
FLT3LG FLT3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 10477595 14670306 15253381 15749884 16418395 16713974 17404308 20547845 25215878 8920882 9268501
FLT3LG FLT3 â—¼   PROTEIN_INTERACTION 11.0 1.0 ACSN 10477595 14670306 15253381 15749884 16418395 16713974 17404308 20547845 25215878 8920882 9268501
FLT3LG FLT3 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10477595 14670306 15253381 15749884 16418395 16713974 17404308 20547845 25215878 8920882 9268501
FLT3LG GATA1 â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 10477595 14670306 15749884 16418395 16713974 17404308 20547845 25215878 8920882 9268501
FLT3LG FLT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9651358 15618475 21389326 25992210 19830725 12681969 15147956 7505204 10080542
IL4 IL5 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 2965306 9834059
IL4 CSF2RA â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 2965306 9834059
IL4 CSF1 â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 2965306 9834059
IL4 CSF1R â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 2965306 9834059
CSF2 CSF2RA â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
CSF2 CSF2RA â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
CSF2 CSF3R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 16720384 11091218 11468284 7691413 16492764 9187659
CSF2 CSF2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 10753826 8910448 11777960 27396825 12393492 19833085 10572088 22323450 23331499 22869907 9211889 24030977 11306493 11867689 9187659 11015446 1702217 2645577 20406969 23046136 20805416 2828352 7957082 18551128 26192618 18692472 21765015 24091328 27216177 2555171 14610620 12811837
THBS1 CD36 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 10657674 11982756 14568985 14996710 17101731 20150200015 21378271 22943793 8349738 9295024 9763615
THBS1 CD47 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10657674 11509594 11982756 14568985 14996710 20150200015 22310103 22943793 8349738
THBS1 CD36 â—¼   PROTEIN_INTERACTION 11.0 1.0 ACSN 10657674 11982756 14568985 14996710 17101731 20150200015 21378271 22943793 8349738 9295024 9763615
THBS1 CD47 â—¼   PROTEIN_INTERACTION 9.0 1.0 ACSN 10657674 11509594 11982756 14568985 14996710 20150200015 22310103 22943793 8349738
THBS1 SDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11257118 1969657
THBS1 CD36 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10487979 10772961 1379600 23640500
THBS1 ITGA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10196234
THBS1 ITGA2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 2478219
THBS1 SDC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 32196115 17879962
THBS1 CD47 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 9169439 15842360 11980922 10397731 8550562
THBS1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 2478219 14963009
THBS1 FN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19542224 11773026 18042364 18226512
CSF1 CSF1R â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 10705574 11306493 20644254 24669294
CSF1 CSF1R â—¼   PROTEIN_INTERACTION 4.0 1.0 ACSN 10705574 11306493 20644254 24669294
CSF1 CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 7883784 8355686 1702217 22483114 22902366 2408759 26235028 22153499 24890514 26095744
IL3 IL3RA â—¼   PHYSICAL_INTERACTION 13.0 1.0 ACSN 11698286 12393492 15034038 15549123 15573129 17200410 18633355 22323450 23026134 23046136 23125331 23762788 24778133
IL3 IL3RA â—¼   SHARES_COMPLEX 13.0 1.0 ACSN 11698286 12393492 15034038 15549123 15573129 17200410 18633355 22323450 23026134 23046136 23125331 23762788 24778133
IL3 IL3RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 23331499 11700046 8649415 9278420 7957082 1465408
THBS2 CD47 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8550562
ITGA5 FN1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGA5 FN1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
VTN ITGA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11331280 23154389
TNC ITGA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9314546
FN1 ITGA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 11423542 1694173 6325925 11801679 18480047 16457822 10772816 9211865 1532572 25237190 26456826 19738201 23154389 22451694 17015452 20643357
RHOA ROCK1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11698448 11729192 11739775 11992112 12194823 12361600 12740575 14657501 14744429 15761148 17517963 18037882 18423981 20535745 21178402 22949611 24857661 24919149 26885855 27048821 27066895 7479854 9362522 9660866 9822605
ARHGEF1 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9789025 12748184 32203420 9113980 9641915 10836144 11149925
ARHGEF12 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9789025 17145710 15364580 23405219 32203420 9113980 9641915 20300064 10592173 11373293 12515866 11094164 11149925
RHOA ROCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 17145710 12361600 25010901 23151663 7479854 27048821 22949611 21281639 26885855 8798490 12727213 17673200 11729192 8816443 10592173 11698448 27066895 11739775 11992112 20535745 18423981 24857661 21178402 23109003 9660866 9822605 17517963 14660612 15774750 12740575 14744429 9535835 12773565 15761148 24919149 26192618 9362522 18037882 14657501 12194823
CD36 BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
SRC APBB1IP â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
SRC RAP1B â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
ITGA3 SRC â—¼   ENZYMATIC_REACTION ✅ 56.0 1.0 ACSN 10671552 11133108 11348595 11476890 11955436 11967263 12051714 12426320 14557817 15001769 15279786 15548370 16039586 16099633 16371504 16474430 16919435 17143292 17303408 17496910 17517963 17660363 17928543 17934056 17936032 18037882 18590585 19010789 19029934 19109155 19171760 19619488 19734908 19920116 20519943 20644162 20705860 21278795 21666923 21900405 22007144 22174153 22203675 22370635 22674073 22703233 23343194 24023259 25572304 25730849 26552706 27216177 7542250 7575488 7594497 8666229
GNAI2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 11007482 11160627 10753828 9722546
GNAI1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 11007482 10753828 9722546
SRC PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 30819914 12181444 11606584 14656219 7682059 15144186 11507089
SRC SPRY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18683950 15564375 12815057 15637081 16000370 15212693 12593795 18678649 16893902
SRC MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12408982 20861316 11113114 10362724
SRC DAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 12795607 18982058 17474147 11724572
SRC ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10330414 17473008 8631894 18156175 25694433 18840695 18364349 18398066 10592173 16935858 21956114 17353363 18088087 12359711 15212693 14996908 15695822 15699036 11723131 20702409
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
SRC CD33 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10206955 10887109
SRC BTK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19109164 23170196 8629002 29455639 10051622 8630736 26165234 9052864
ROCK1 MYL12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8702756 11283607 26169356 12185584
CD4 CD3D â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 HLA-DRA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 CD3G â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 CD3E â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
RASGRP1 RAP1B â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16076873 15469846 15334074 16757337
TNC FN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 7499434 20708078 21349332
IL1B IL1R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 8332913 7878046 1833184 20802483
HSPG2 ITGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15240572
LAMA1 ITGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9688542
FN1 ITGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7688313
VTN ITGB8 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 7525578 7559467 17968485 9251239 7685013 9443892
VTN ITGA2B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 2412224 2420006 7685013 7542669
VTN ITGB3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 7525578 7559467 17968485 9251239 7685013 9443892
VTN ITGB6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8120056
VTN ITGA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7559467
VTN ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16195248 11331280
VTN ITGB8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11156415
FN1 ITGB6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 1694173 18480047 1532572 17015452
PPP1CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20186153 14633703
AKT1 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27053161 16107690 20101202 8206977 26680303
AKT1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18578522 10896934
AKT1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 70.0 1.0 Omnipath 12759249 20166139 11756412 10376603 11923280 12446767 16697215 11044445 20398329 18372248 11696579 16126727 16839566 15808505 20138985 20299462 10908731 20363286 11988487 11425855 20214616 23103584 11729179 16043647 17570479 12171920 25460366 27322328 11978735 15169778 11029403 25241761 19654415 10949026 18048761 11715018 12791703 24379783 18636226 9812896 23397142 17680028 10376602 12431978 10722653 20832730 18570873 25009123 17052453
AKT1 ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24947355 18250332 16332683 18955969
AKT1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11546794 14500673 12176337 11445557 9736715 12149249 11278835
ITGB3 RAP1B â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
ITGB3 APBB1IP â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
FN1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11423542 1694173 18480047 1532572 8663002 17015452
CR2 CD19 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9597125 14688345 31732528 1702139
PRKG1 TBXA2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11516166 9915793 17466390 9560198 14530262
PRKG1 VASP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 10922374 20058876 8182057 15694326 20166139 14679200 7925440 23867907 94237860 20483741 17570479 17287340 9685341 21702043 15066263 15212693 10851246 12576312
PRKG1 PLCB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19651622 11278298 10893237 9660757 15302935
FN1 ITGA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7559467 7626807
FN1 ITGA2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8663002
CSF3 CSF3R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 10537111 10364174 15676205 16492764
GNA13 ARHGEF12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12515866 11094164 12024019
GNAI2 ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
GNAI2 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 2121366 8327893 19703466
GNAI2 ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
GNAI1 ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
GNAI1 ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9748257 23109003 15539636 7935349 16460834 11376933
HLA-DRA HLA-DOB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DRA CD3E â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DRA CD3D â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DRA CD3G â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TBXA2R GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23962128 20590159 15134434 12726995 12193606 9152406 15782186 21940795 31160049 12399457
GNAQ PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11753430 1309799 12193606 16754659 8245028 8387502 1322796 1846707
ITGA2B RAP1B â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
F2R GNA13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8290554 20223821 10922491 16189514 22318735 22972936 21331223
TBXA2R GNA13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8290554 10395940 15782186 31160049 10488151 12399457
GNA13 ARHGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14607242 9641916 9641915 16189514 12681510
PIK3R3 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8596638 22402981 11733063 25814554
F2 GP1BA â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F12 GP1BA â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 1998667 588558 893417 10781579
VWF GP1BA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17145710 19286885 15039442 6336654 12087105 7690774 12183630 2690940
HLA-DQA1 CD3D â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD3D CD1D â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3D CD1B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3D CD1C â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3D CD1A â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD1A CD3E â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
HLA-DQA1 CD3E â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD3E CD1B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3E CD1C â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3E CD1D â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
FGA BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
F2 FGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25241761 2133223 2742826 1587268
F2 GP1BB â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F2 VWF â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 19240027 8052958 2104766 15705787 1851341 2109644 1973901
F2 GP9 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F2 GP5 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F2 F2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9058715 10978167 15707890 10644723 14652070 11356985 23450633 18250335 12563219 22972936
F2 F2RL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1273221212732210 12732212 22318735
F2 GP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 2207326
FGB BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
IL5 IL5RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 23331499 1833065 7721873 10823900 1732409 10880230 22528658 7957082 1495999 8567620 11748263 22153509
FGG BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
BTK PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 19901323 19690332 15184383 16497976 33419778 34141433 15509800 30344948 12235209 14656219 17290227 12780340 12181444 11606584 21074890 7682059 11507089 15144186 22409342 29455639 17239630 10498607
HLA-DQA1 CD3G â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DQA1 HLA-DMB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA1 HLA-DOB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
EPO EPOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17145710 8662939 9442088 15358619 9030560 9974393 9774108 18586265 23331499 2163696 10318834 21889455 17327410 16982323 29997244 9808045
ITGA2B APBB1IP â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
COL2A1 ITGA2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7520045 10772239
VWF ITGA2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 31035301 1737795
GATA1 EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16471262 8677751 8288642
CD3G CD1D â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3G CD1B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD1A CD3G â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
MYLK MYL12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23790394 24144337 26827725 29046396 17924679 21345328 11815633 28878690 11062269 19690332 18773891 20510202
CD3G CD1C â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
LAMA1 ITGB8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7542940
COL2A1 ITGA10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9685391
F12 GP9 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 1998667 588558 893417 10781579
F12 GP5 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 1998667 588558 893417 10781579
F12 GP1BB â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 1998667 588558 893417 10781579