BRCA1
|
SOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15574597
|
BLVRA
|
HMOX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14988408
|
HEXB
|
OTUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
OTUB1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19996094
|
VCP
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
DLD
|
GCSH
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16263718
9242632
|
NTAQ1
|
HPRT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
MAP3K7
|
SHARPIN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16260783
16953224
|
COX5A
|
COX4I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
17418790
8194600
|
COX5A
|
COX4I2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
17418790
8194600
|
PRKCZ
|
VHL
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5219754
17350623
|
DNMT1
|
CFTR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1375221
10417323
|
PRKAB1
|
ACACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16326698
9029219
|
ADSL
|
GART
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
OTUB1
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
34591986
20622874
19996094
|
CYCS
|
DLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
815.0
|
0.81
|
STRING
|
36370105
|
COX5A
|
COX8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
CUL3
|
CUL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21145461
22709582
|
CHIT1
|
VHL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
AOC3
|
EXTL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CYC1
|
CYCS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
CUL3
|
ACLY
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
21145461
27664236
|
GNMT
|
HPRT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
CFTR
|
ALDOA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26618866
31324722
29924966
|
BRCA1
|
FANCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
SOX2
|
EHMT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
35140242
23667531
|
CYCS
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
9390557
|
TRAF6
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
HPRT1
|
SREK1IP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
COX4I2
|
CYCS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
DNM1L
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
EHMT1
|
EHMT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
EHMT2
|
EHMT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21430779
26028330
27705803
21258344
24981860
34588438
28698370
|
CFTR
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
ACACA
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19061860
29899443
16713569
16326698
30257991
24565757
12360400
16698035
18452305
|
FANCA
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21240188
29656893
16713569
12354784
|
DNMT1
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19943104
22197621
20631324
|
DLD
|
GCSH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
24256811
10103005
24341803
|
GLDC
|
GCSH
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
3.0
|
0.9
|
Reactome
|
2025283
1959641
1993704
|
LRRK2
|
DNM1L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22228096
22639965
24282027
29541021
23813973
|
TRAF6
|
MAP3K7
|
â—¼ UBIQUITINATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
18758450
|
ATP6V0C
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
925.0
|
0.92
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V0D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
ATP6V1C1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
COX5A
|
COX6A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
ACACA
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
COX5A
|
CYC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
MAP3K7
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
BRCA1
|
ACACA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
16326698
19793801
20029420
21060331
21337561
25979092
|
BRCA1
|
ACACA
|
â—¼ PROTEIN_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
16326698
19793801
20029420
21060331
21337561
25979092
|
BRCA1
|
ACACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
16698035
19061860
12360400
24565757
18452305
16713569
16326698
|
CASP9
|
CYCS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9390557
25313070
20462491
27697150
|
PRKCZ
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
16287866
|
CYCS
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19788417
16977332
9390557
16713569
12147322
12773388
10329646
12792650
15210107
|
TRAF6
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11274345
12150927
12620219
14660645
15125833
16252010
17948050
18264787
18758450
18922473
19161412
|
TRAF6
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
17145710
19675569
17947236
19843958
10882101
19521662
11259596
17079228
28024152
31885808
19112497
22924441
10094049
27501752
18922473
11518704
11809792
16517750
19232515
10702308
16410796
14633987
19820695
22851693
10921914
18758450
12496252
12609980
21822258
12242293
25963657
24434549
27249171
22643835
21245467
17965022
26038599
|
VCP
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
33444648
11733065
28115426
15652483
10811609
29153394
|
MAP3K7
|
KSR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11741534
12941695
|
MAP3K7
|
PRKAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16054096
16054095
15509864
19197243
17244528
18692468
15980064
|
EHMT2
|
DNMT3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19308066
|