Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 AIMP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0800297105 18695251
MYC AIMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
FUBP1 AIMP2 â—¼   COLOCALIZATION 2.0 0.8 intact 8145365 21285945
KARS1 AIMP2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
APEX1 ACTB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16431169 11082319
GAPDH APEX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18776186
BAG2 CCAR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
TP53 CCAR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20160719 20074560
CSNK2A1 CCAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24962073
TNFSF12 CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AURKA CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
MAPK1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17205132
TARDBP DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC DDX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
HSP90AA1 DNAJA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
DNAJC7 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
HIF1AN EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12573436
FEN1 ARHGDIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PCNA FEN1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7876218 8131753
FOXM1 CCNE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16504183 5218380
FOXM1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16809346 17875680
FOXM1 CCNE1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16504183 5218380
CCNE1 FOXM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15024056 16504183
FOXM1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16809346
HSP90AA1 GIGYF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
GIGYF2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
TXN HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAZ HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
QARS1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212831 10913161
HSP90AA1 FASN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
HSP90AA1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HSP90AA1 MAVS â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20628368 16394098
HIF1A HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14726529 20068160
HSP90AA1 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18591668 21465483
YWHAZ HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
MYC HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10737792
ESR1 HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
IMMT MAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
MAPK1 MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16709866
MAPK1 PFAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32485148
MYC MSH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12808131 11983916
TP53 MSH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12209975
TARDBP MYC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC SHMT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18628958
MYC LDHB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC RAN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23468463 11085504
MYC PGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18809243
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
NPM1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
RHOA OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20553488 7717051
UBA1 OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19996094
TP53 PARK7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23447676 23149933
SMAD2 SNAI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19389392 18618014
HIF1A SNAI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23979441 23496980
UBE2L3 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
STUB1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19940151 25637186
TLN1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
UCHL1 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
TP53 PPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 PHB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7717349 20134482
AURKA TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 14702041 19121998
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
TP53 SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21900401
TP53 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23940366 9360971
TP53 PTMA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9185588 18856068
TP53 TXN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 16096367
TP53 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16917513
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
TP53 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7915517
YWHAZ UBA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PDIA6 USP47 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PGK1 PCNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
PCNA ENO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
PCNA GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
PCNA ALDOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
GAPDH PCNA â—¼   COLOCALIZATION 2.0 0.8 intact 7995081 20849852
PCNA ENO1 â—¼   COLOCALIZATION 2.0 0.8 intact 7995081 20849852
PCNA ALDOA â—¼   COLOCALIZATION 2.0 0.8 intact 7995081 20849852
YWHAZ CAD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ EIF4A3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAQ EIF4A3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PFN2 SGTA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UCHL1 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RANBP1 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12649209 5216249
CTNNB1 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATP5F1B PSME3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TGFBR1 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18511908 6798777
TGFBR1 SMAD2 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 10973958
TGFBR1 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19726546 15761153
DLD CALD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TXN GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TXN YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HIF1A TXN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20347035 17220299
TXN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19737086
ATG5 UCHL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAVS CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CALR YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CALR LETM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PSME3 DEPTOR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
UCHL1 NEDD8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NEDD8 UCHL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VHL HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
HIF1A NR4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14729605
HIF1A UTS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20616367 22399808
HIF1A HIF1AN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24421387 19726677
HIF1A PKM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020
HIF1A BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020 17043658
HIF1A CD274 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24778419 27141364
CSNK2A1 HIF1A â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17382325 5219810
HIF1A ALDOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8089148 8955077
HIF1A PKM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15379897 8089148
YWHAZ CAND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CTNNB1 VHL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16983094 0606850103
MTPN HIF1AN â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 17003112 0606877103
YWHAZ CSE1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
TRAF3 BIRC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18997792 18997794
BIRC3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23070005 18485876
TRAF3 BIRC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18997792 18997794
YWHAQ USP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
CTNNB1 GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAZ GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ PGK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CFTR CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12208510 5215704
ESR1 ARHGDIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21447808 11060289
HSPA5 DDX24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
YWHAZ ALDOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PHB2 PHB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
HSPA4 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
ESR1 YWHAQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22329840
ESR1 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9259323 8625613
ESR1 CKB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17272396 10411295
HSPA5 PSME3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TARDBP FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BMPR1A BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10712517
LDHB YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
BCAP31 FDPS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAZ P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PFN1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ BCAP31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ NME2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PKM YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ FASN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
GARS1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ AARS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
STUB1 UBE2D4 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
APEX1 EP300 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HSP90AA1 MAP3K5 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
OTUB1 FOXM1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31879190 26148240 27167337
NEDD8 OTUB1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 33665565 18954305 24654937
SRP54 SRPRB â—¼   PHYSICAL_INTERACTION ✅ + 0.81 0.81 Signor 30649417
CFTR YWHAZ â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
GNB2L1 SEC61B â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CCNE1 PCNA â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
DDX23 LSM3 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
ESR1 APEX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
MYC CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
VHL DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 21942715
ACTB EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33742100 21988832
CFTR IMMT â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
MYC IMMT â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
IMMT PHB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31536960 34079125
MYC ELP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC NAT10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC PHB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
MYC NSUN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC LBR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC ARF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC IDH3B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC CKAP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC UBA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
BIRC3 OTUB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23524849 30948266
OTUB1 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32814053 18954305
PARK7 PRDX6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31536960 29128334
SMAD3 NR4A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33990575 21988832
CALU CALR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26344197
ESR1 CAND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
ESR1 AURKA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21761334 31527615
AURKA CNOT8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CFTR PDIA3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
YWHAZ USP8 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5217040 15161933
FUS PGK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25192599 26344197
CFTR ARF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
ALDOA CARM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GPX4 PRDX6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 21988832
ESR1 MAP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
ESR1 ABCF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
SRPRB UBL4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 23246001
ESR1 STUB1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
PARK7 PRDX5 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
CCNE1 CDK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9053846 9891079 1388288
ESR1 IMMT â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33731348 19805454 31527615
BIRC3 UBA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23524849 30948266 25260751
PCNA CCNE1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TRAF3 BIRC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20097753 30561431 33608556 23524849
SRPRB ARF5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ESR1 PDIA6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33731348 25604459 31527615
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
UBA1 UBE2E2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CFTR HSPA4 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
EP300 VHL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
UBA1 UBE2G2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CTNNB1 SMAD3 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
SNAI1 EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28296173 25314079 32494626
EP300 RAN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12649209 33742100
MYC ACTB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11839798 29467282
MYC HIF1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 15071503 28205554
PCNA CCNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 7903056 33961781 8101826
TRAF3 BIRC3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20097753 33608556 23524849 23612708
ANP32A ANP32E â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
DDX5 ESR1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
MRPS7 TUFM â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
HIF1A APEX1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10594042 16189514
CFTR RAN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31324722 29924966 17110338
SMAD2 ESR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20207742 11555647
CFTR ALDOA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 31324722 29924966
CFTR PRDX6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 31324722 29924966
NEDD8 VHL â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
UBA1 UBE2D4 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
HSPA4 SGTA â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
PCNA APEX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16189514 11601988 10559261
EP300 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 15824515 15688032 16109717 15345715 20564330 9843571 15133024 10497242 17469184 15623506 10575014 15588252 18055455 16876108 21567395 11134049 12743039 11058129
MYC IRS4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17314511 30415952
OTUB1 PCNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26752685 18954305
PRDX6 PCNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26030842 20849852
PCNA CALU â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22863883 26030842
VHL PDCD5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 24469044
EBNA1BP2 EIF6 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CACYBP CTNNB1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
ESR1 PTGES3 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CSNK2A1 NAP1L4 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
UBA1 UBE2W â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CARM1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16923966 18280497 11997499 21988832 11701890 32140074 28844863 15731352
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
PGK1 PCNA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26030842 20849852
ESR1 ACTB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31527615 20308691 19805454 21182203 21182205 20348541
ATG5 MAVS â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22749352 17709747
VHL NEDD8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16503656 17353931 15060148 18323857 11024059
PHB2 PTMA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12943695 16189514
ESR1 PHB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10938099 24051437 12943695 26052702 17932104 19805454 28555617 10359819 15140878
FUBP1 FUBP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29395067 33961781 26344197
DNAJB1 HSPA4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ACTB MAPT â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
FEN1 MSH2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
GNB2L1 HIF1A â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
HIF1A HSPA4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ESR1 PHB2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CFTR STUB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA4 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
AURKA TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MAPK1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
NPM1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
SMAD2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
FEN1 APEX1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 11601988
FUS EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18509338 30110629 33742100
EP300 SMAD2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11371641 21988832 10199400 12237408 11264182 15623506
CCNE1 FOXM1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16504183 15024056
OTUB1 MSH2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33640455 19615732 26752685
DDX54 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12466272 21182205
MAP3K5 YWHAZ â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ESR1 HSPA4 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
HSPA4 MAPT â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CARM1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
COPB1 TMED10 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
GART PAICS â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
SMAD3 DDX5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15464984 18548003 19917253
EP300 NR4A1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21988832 12082103 16713569 20438716
EP300 PTMA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11967287 10891508 16713569
HIF1A SMAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12228247 28471448 11486006 14741200
CFTR CALU â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26618866 22768251 29924966 17110338
CALR P4HB â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
SMAD3 TGFBR1 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
KARS1 AIMP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FGB AIMP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LUC7L2 AIMP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
AIMP2 ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FUBP1 AIMP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21988832 21285945 12819782
EP300 APEX1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14633989 20856196 20808282 30110629 19934257
TP53 APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18208837
ESR1 CCAR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21596782 20074560 17473282
CD44 TLN1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 22566907 23620508 23886063
MYC CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22002305 22911891 19738061
TGFBR1 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12145287
CCNB1 CDK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 34224728 18337751 9891079 24508230 17431037 9560267 14681455 17283331 8662825 19162005 16159883 25852190 20360007 19879842 12397081 11331587 9247342 26496610 20228808 25750436 12612082 16784539 23602568 20733055 27626412 20367638 8397206 10973963 9001210 20956543 33037310 8397207 23543736 32707033 2570636 30674583 10716937 27030811 18408765 24358021 20974803 7799941 33961781 26186194 17679094 23799914 8463339 26344197
CDK1 FOXM1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 18285455 19160488 15024056
DDX5 FUS â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
DDX5 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 33742100 12527917
DDX5 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 25604459 12738788 20308691 11250900 21182205 10409727
EP300 DDX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12527917 20663877
EP300 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11268218 16713569 18263614 12937166 24939902 14988403 33742100
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
EP300 FEN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11430825 20019387 16326861
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
RHOA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MAPK1 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19941816
MAPT STUB1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
MYC MSH2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28628118 17314511 12584560 29467282 28205554 30415952
TP53 MSH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11350971 8630028
SMAD2 MYC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11804592 28628118 28205554
MYC DDX24 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21150319 17353931 30415952 29467282
ENO1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 18490439 19219071 2191300
MYC NAT10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC GAPDH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC ESD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC STMN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC ARF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PHB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
MYC SLC25A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC LBR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14519204 12695333
MYC RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22159222 20383141 22235332
ENO1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2191300 18490439 19219071
OTUB1 UBE2N â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24071738 30718280 32049508 22367539 25872870 26752685 27173435 27909234 19615732 20725033 22679021
TP53 RRM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15843459
CSNK2A1 SNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19923321
TP53 PHB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16918502 14500729 21829624
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
TP53 SLC25A5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24076372 9671769 12080472
TP53 UBD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21396347 18431400
UBL4A SGTA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 25036637 23533635 23246001 19615732 25415308
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
ACVR1B SMAD2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11024047 12063393 14978253
ACVR1B SMAD3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11024047 12063393 14978253
ACVR1B SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14517293 23331499 9605406
TXN PRDX5 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 21385867 10514471 17519234
ESR1 SEC61B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
PDIA3 CALR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 12052826 10436013 24981860 30021884 11823531 26344197
RHOA PFN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22820501 22479341 27228149
ESR1 AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21761347 21761334 18497064
TRAF3 MAVS â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16858409 16306936 17190786
GAPDH KARS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CSNK2A1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14675149 25862939
CTNNB1 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 21362399 21986938
SF1 FUS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9660765 16713569
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SMAD2 TGFBR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HSP90AA1 HSPA4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
STUB1 UBE2W â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
MAPT YWHAZ â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
MSH2 PCNA â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
UBE2N UBA1 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 31638574 14517261 18678647 25527291 27173435 30097011 33619271 27182664 29537486
SGTA UBL4A â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
HSP90AA1 STUB1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
UBA1 UBE2L3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
GAPDH PGK1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
HIF1A HSP90AA1 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
UBA1 UBE2N â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
HIF1AN HIF1A â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 6802010 19071119
CCNE1 CDK1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
MAVS TRAF3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CALR CALU â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
APEX1 TXN â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
USP8 YWHAZ â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
UBE2D4 UBTD1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
PCNA MSH2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 15225546 12171929 16189514 8858149
ACTB PFN1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RAN RANGAP1 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
TRAF3 MAVS â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 27348524 27980081 32366851 32324863 29125880 22792062 22022264 30267576 22079989 31806368 20080758 21200404 22908223 30527812 33608556 31390091 26221961 24622840 16858409 33582548 19419966 22901541 32511263 19893624 26519536 23545497 33411856
AIMP2 KARS1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 21900206 2001699 8089645
HIF1A EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17382325 5219810
RAN RANBP1 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
HIF1A EP300 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15280364 19589782 16543236 11823643 22807441 19666581 16189267 18047470 15342390 12042299 19680224 22735262 23448368 26135796 23618863 14691445 19696166 11959990 27320910 16847340 24821806 22789427 17906695 8917528 20620956 20000859 15261140 16081065 12778114 22219185 15154850 25192544 22075993 19071119 22908229 19940151 21187066 24421387 23880760 11940656 23966271 26826385 26944191 12588875 23746844 11063749 27808477 19074848 20603618 15155277 18268343 20829524 21148070 12914934 17502379 22684029 17382325 26751287
FEN1 PCNA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 17115032 7673186 8876181 1477073 14657243 16216273 26030842 31467278 26496610 11430825 12853968 26751069 32900933 22592530 8668533 26264872 11313979 30184152 24958773 24728180 11601988 9545252 9178907 15616578 9305916 18692475 29997244 22556262 15576034 33961781 26186194 22606318
HIF1A VHL â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15082527 11865071 11226425 10944113 14556007 11986208 15527772 17973296 12538644 26735336 24899725 12606543 21358672 24015760 16611863 23401859 18062927 21332579 15805242 19940151 12086861 27281823 23413029 33060856 11292862 24316222 16155211 24857547 22932900 29121446 11292861 12101228 15060148 18047470 16278378 21602890 27320910 12464182 26611735 32589900 18402654 25500545 12050673 18694926 26215701 10878807 25361009 11641274 22351759 34007068 18305400 21316481 11024059 34195792 26037477 34174286 33039559 10823831 26743088 31810986 10353251 15833858 17558023 11566883 23580587 27563096 18985005 19123984 25438054 12682018 18323857 23387829 17442832 33550096 18222538 18426857 17047048 12004076 34230460 23318261 33961781 12808024 21335603 12586829 17353276 11358837 28514442 20724477 16140212 12205091 20049704 16862177 11331613 32535973 15721254 14691445 15385570 10973499 15611064 17981124 28775317 12925778 26496610 17339318 30237125 20458141 20639890 17986458 19147576 28425505 11504942 22369643 18264140 16511565 12351678 14600153 30988076 17132228
CSE1L RAN â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
OTUB1 UBE2N â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
HSP90AA1 PTGES3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
STUB1 UBE2N â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ARHGDIA RHOA â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
COPA COPB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HSPA4 STUB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
HIF1A HIF1AN â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
FEN1 PCNA â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 HIF1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PCNA APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
MYC APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14519204 11983916 12695333 11085504
FEN1 APEX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11601988 16189514
EP300 APEX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14633989 20856196 20711647
CSNK2A1 APEX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20955519 20507565 10023679 19118383 21576760 18583988 15066279 20471329 21592330 9407949 21118972 20533398
APEX1 TXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9108029 11118054 18586825 10585464 8736558
APEX1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18786561 19180539 9119221 19737086 16713569
BAG2 STUB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16169850 16207813 25036637
CTNNB1 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18483247 12782598 17724465 10027409
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
MYC CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18802399 2237430 8065306 11085504
TP53 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 10825186 11593387 12874009 19472317 10514438 11313928 16807237 8270002 17942917 9275177 20395210 11032828 19861536 12889596 19067706
CDK1 RANGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15037602 17570479
CDK1 FOXM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23240008 19737929 28387346 19160488 15024056
CDK1 FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 33770148 12853968 20729856 18443037 22749529 20929870
CDK1 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 49.0 1.0 Omnipath 17081983 12058066 27253419 22285574 25908633 20333249 16912078 27553022 19933706 16083285 20068231 27619510 17570479 18669648 7213797 81161106 26536659 11278991 17287340 17924679 15190079 14670079
CDK1 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 7592773 30392930 18691976 19387552 20068231 96029687 16371510 1400350 19941816
CDK1 MAP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 19691289 15216889 10791892 20068231 17570479 11683421 19664995 9398320 19415658
CDK1 IREB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18574241 21348856
CDK1 UBA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19651622 20068231 7724583 19413330 7673335 18669648 9099746
CDK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 24173284 12767922 1584757 20661218 26029996 2141171 9467949 17570479 20808790 7862459 11327730 11078726 27726420 8357826 16713569 2156209
CDK1 STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 83.0 1.0 Omnipath 17081983 18767875 9731215 20230923 19690332 17693683 11135364 19413330 18187866 19664995 19415658 18578522 16083285 20068231 18452278 94064639 1737801 18491316 18669648 8245003 16427064 93315482 17287340 16094384 19651622 20058876 8376365 8325880 17924679 18220336 19664994 18707149 8125092 8325881 16964243 33839152 18212344
CDK1 LBR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 14718546 9045635 17570479 20576617 21795390
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
ARF4 COPA â—¼   PHYSICAL_INTERACTION 17.0 1.0 Reactome 1680566 16926190 22013193 8505331 10318838 17451557 1631136 17360540 9751720 21844168 8132710 9114004 10921873 1957170 1898986 22304919 16940185
ARF4 COPB1 â—¼   PHYSICAL_INTERACTION 17.0 1.0 Reactome 1680566 16926190 22013193 8505331 10318838 17451557 1631136 17360540 9751720 21844168 8132710 9114004 10921873 1957170 1898986 22304919 16940185
DDX5 CARM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14631847 12498683 11010967 14675539
DDX5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24219989 15660129 20876186 19626115
DNAJC7 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19875381 20661446 12853476 15189447
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
CARM1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15731352 21988832 11997499 11701890 15616592 16923966 18280497
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
EP300 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21988832 20438716 12082103 16713569
EP300 FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19608861 11430825
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EP300 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 21988832 23331499 9169454 12237408 10199400 11264182 7878020 8047140 12958365 19171760 11371641 16027720 17074756 17469772 21269274 15623506
EP300 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 24821806 12573436 17145710 16847340 12588875 19589782 11940656 25192544 11959990 18519678 23448368 22219185 11823643 12042299 15342390 23746844 19071119 19680224 27808477 15154850 19696166 8917528 17906695 18268343 22735262 21148070 15261140 19940151 23880760 22807441 35430356 14691445 12914934 20000859 12778114 26751287 16081065 22789427 16543236 24421387 17382325 17502379 22684029 21187066 19074848 23618863 23966271 20603618
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
PCNA FEN1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 11283614 11756412 12202749 14624239 14726013 15385537 15703371 15871698 16216273 16449207 16697054 17055429 17116323 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19847258 20027199 20056333 20064462 20691907 20713526 21376743 2191300 22021614 22657828 22743550 22973052 23082994 23161013 23253856 23414611 24036544 24050180 24709898
PCNA FEN1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 11283614 11756412 12202749 14624239 14726013 15385537 15703371 15871698 16216273 16449207 16697054 17055429 17116323 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19847258 20027199 20056333 20064462 20691907 20713526 21376743 2191300 22021614 22657828 22743550 22973052 23082994 23161013 23253856 23414611 24036544 24050180 24709898
PCNA FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 28514442 15576034 8668533 3113402 11601988 12853968 31467278 1477073 24958773 7673186 16216273 11313979 15616578 8876181 14657243 11430825 26496610 16189514 9305916 22606318 28073635 19153658 26751069 26186194 9178907 22592530 24728180 17115032 18692475 26030842 16326861 29997244 22556262 9545252 31515488
HIF1A FOXM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22831955 19097132
MYC FOXM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20658516 18798339 12695333 17341548
FOXM1 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11572993 19276163 15671063 11682060 19097132 23812424
FOXM1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15817462 15689977 10567581 11572993 11682060 15024056 11391529
FOXM1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17141659 10567581 17655499 16965535 11391529
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
PTGES3 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 16565516 10642522 11447118 26804907 15916966 11413142 16403413 21988832 11812147 19875381 19740745 14761955 12077419 10811660 20039095 22806877 25036637 20048054 19996313 18285346 20661446 22315411 23022381 18172314 20159553 22729780 22504172 16289154 9817749 14987994 8114727
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
MYC HSPD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19022255 12695333 14519204 21995449 11983916 11085504
NPM1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 31434245 22955283 12748172 16009132
MAPK1 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
MAPK1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
MYC MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22789855 21933022 16596619 23617883 8013639 20144848
MAPK1 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 67.0 1.0 Omnipath 9614189 9832145 12387894 12766916 12765608 12414518 19413330 1330687 24116116 19415658 15302935 33961674 9716264 34493616 31178717 28066266 15324364 31065832 25573097 12801934 29298849 16165272 15883264 16115884 8166686 33952699 9565682 11181841 34536819 10737616 7566346 18315566 9771888 29760653 34480088 24301651 15542598 18055457 12226093 7488031 9199504 18510355 21731772
MAPK1 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11883936
MAPK1 STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 26881937 20630875 22028470
MAPK1 CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10659854 12438317 15890648
MAPK1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 23331499 10197981 34504019 18775330 20659902 8226933 9620846 16156666 9604935 18988627 12193595 11027280 8388392 27153775 31995604
MAPK1 CALD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10751321 10514499
MAPK1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 19218245 18032789 18729074 16156666 19914161 23331499 19914168 24080014 8226933 14512875 15520018 20736297 26497676 12193595 26297431 18988627 8388392 10197981 15241418 18775330 9604935 9380693
MAPK1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16954218 10551817 18519666 18687685 26784107
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
MAPK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10551811 17081983 8386367 17251036 91332050 17570479 1748630 7957875 27167001 15212693 1651323 15210690
MAPK1 PRDX6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 28055018 19140803
MAPK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 14965474 9765199 15116093 21675959 23443559 10781582 25241761 10446957 10958792 11409876 11709713 21147777 10673501 11551930 15867353 11875057 12091386
PCNA MSH2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20154325 22118461 11274057 23840062
DEPTOR MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
MYC GAPDH â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199147 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
ENO1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10082554 10528225 17595061 10802057 19846662 11134351 23421821 10403782 18490439 14506152 20886042 7880838 2005901 9074493 18070418 21559732 9119380 20412594 10681589
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
MAZ MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8844723 9294605 2721961 21559684 10383467 10669750 8355712 11527412 7988563 1549358 1567856
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7739536 10931841 11673469 10657901 12177005 14519204 9111322 9811896 10567564 17706770 24771621 11983916
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
MYC PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7597041 18358094 22911891 18809243 1280813111085504 11085504
MYC PAICS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12695333
MYC CCNE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18802399 20607601 14519204 22583478 9188852 11983916 11509615
MYC NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15589822 16857742 14519204 23271972 11983916 11085504
MYC CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12747840 11522645 11983916 19470724
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
MYC PTMA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8196628 15840017 8378090 1378271 8524267 12695333 9185588 10380878 9365169 17372028
MYC AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20890087 20519624 14744757 20682043
MYC TXN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16099847 12695333
MYC NME2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15530864 14519204 11960382 19435876 18414489
MYC HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1534087 14519204 1562593 10446203
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
FUBP1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15502847 2191300 18490439 19219071
MYC SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
NPM1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 23443559 15144954 16740634 15310764 16376884 12080348
OTUB1 UBE2N â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22367539 21130715 24145445 21763684 35500217
TXN RRM1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 8.0 1.0 Reactome 18997010 10884394 2668278 11796141 16756507 9677297 16373698 19176520
SMAD3 SNAI1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16179589 16713975 17018611 17563753 18768831 19597490 21041997 21042762 21577210 21614932 22331441 22514743 8515656 9389648
SMAD3 SNAI1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16179589 16713975 17018611 17563753 18768831 19597490 21041997 21042762 21577210 21614932 22331441 22514743 8515656 9389648
SMAD3 SNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20731704 9389648 18832382 16831886 17563753 22406545 11074002 21317430 16617148 17671186
PTGES3 STUB1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20093776 20713526 20959453 2191300 21945180 22032831 22869732 23430059 23551398 25103413 25487024
PTGES3 STUB1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20093776 20713526 20959453 2191300 21945180 22032831 22869732 23430059 23551398 25103413 25487024
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
TP53 FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12734185 19861536
TP53 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10321841 7915517 15358233 12217864 10516009 1705714 8570655 16980608 9707425 15950182 19789303 11313928 1356162 12384701 9858527 12947108 23390122 8524244 9651310 1352831 7909518 11032828 10910968 12485898 10618724
TP53 MAP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10521394 10446979 19411072 10990460 8956998
TP53 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12874009 14627709 10051609 11313928 17942917 11892838 15710382 20395210 19470724 12379461 11071927 11522645 15737644 11162602
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
NR4A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23071566 17139261
AURKA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 24173284 22864622 25217103 24089029 16713569 19413330 25848977 17999753 23565200 25333414 23201157 16552184 10884347 1956339 26186194 29455673 15469940 15749021 18974145 21502403 17287340 28043820 22396649 92065884 12198151 27933271 22852086 12064478 30266789 25398437 17259342 22350019 25634113 14702041
TP53 PHB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24380853 16918502 20134482 14500729 16319068 16713569
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
UBE2N PCNA â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10880451 16224103 16518696 17652783 18157158 18196958 18525240 18647995 19217833 19258535 19851286 20675655
UBE2N PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 18772547 12820959 18525240 19459846 19258535 19440234 17652783 15147722 10880451 15169778 19851286 10722742 18647995 18006823 18157158 16224103 20675655 16518696 18196958 15340381 10721693
ESR1 CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16675542 12746293
GET3 SGTA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20676083 27193484 21743475 21636303 28104892 23129660 25179605
ACTB RHOA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
PFN1 ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17541406 8413665 563468 10600384 10411937 10592173 19000816 16189514 19338310 9463375
COX5A COX5B â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX5B â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
RANBP1 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 10779340 11832950 12649209 9111043 10811801 7603572 9315840 20805321 7891706
RANGAP1 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7744835 8146159 9219684 16189514 10394366
GET3 UBL4A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20676083 27193484 21743475 21636303 28104892 23129660 25179605
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD3 SMAD2 â—¼   PROTEIN_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
TGFBR1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 14557817 15265520 16474430 17934056 20060931 20519943 21614932 22703233 24132110 24336330
TGFBR1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 10678166 12220225 9892009 9463378 16024789 9136927 14625308 11792802 11133108 19920116 14557817 11278410 15134444 10085140 23331499 21071413 20060931 17934056 18511908 21614932 18988627 10973958 23221174 8980228 9311995 9346908 9235954 20519943 21900405 15350225 15548370 26057631 19010789 15104092 16474430 9346966 30093905 12957874 11744690 9525694 15212693 11274345 9865696
ACVR1B SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 9346908 11389842 9892009 18988627 14517293
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
TGFBR1 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 14557817 15265520 16474430 17934056 20060931 20519943 21614932 22703233 24132110 24336330
TGFBR1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 15104092 9311995 8774881 25714018 11438668 19458083 11792802 12957874 19701891 9380693
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
CSNK2A1 PTGES3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17081983 15040786 18088087 18166671 16094384
MAP3K5 TXN â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 11274345 12556535 12655147 18792398 20414655
MAP3K5 TXN â—¼   PROTEIN_INTERACTION 5.0 1.0 ACSN 11274345 12556535 12655147 18792398 20414655
TXN MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 19018770 25098452 12089063 34837535 10843682 17331951 20385180 9564042 23291592 19880523 21771788 19805025 11689443 15696199 12077134 17724081
CALR PDIA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
CALR PDIA3 â—¼   PROTEIN_INTERACTION 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
YWHAQ MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17145710 15023544 17389591 19880523
ARHGDIA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 10489445 20628200 11368848 17353931 9490022 9113980 25416956 20711218 16189514 15659383 14749388 11149925
HIF1A VHL â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
HIF1AN HIF1A â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11641274 12042299 12080085 12215170 22841746
VHL HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
HIF1A ALDOA â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A PGK1 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A ENO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19828020 8955077 15459207
HIF1A VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12205091 15930297 21887475 22150821 22396654 15962286 23159849 17482131 17140440 16883594
HIF1A ALDOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19828020 8089148 8955077 9748288
HIF1A GAPDH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19828020 12193088 15967517 21338575 11955624 15132953
HIF1A PGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15794924 19828020 8089148 18024476
HIF1A HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15794924 14726529 20068160 18844219 18683594
HIF1A AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18562694 19828020
HIF1A HIF1AN â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 6.0 1.0 Reactome 12615973 11823643 14701857 12042299 12080085 15239670
HIF1AN HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 12573436 11641274 14734545 12042299 12215170 12446723 17244529 19071119 17003112 12080085 19696166 16189514 19940151 24145445 26751287 12432100 26972000 17382325 19074848 26752685
VHL HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 123.0 1.0 Omnipath 17145710 21332579 24857547 12682018 26496610 11292861 11024059 15060148 16278378 12586829 17353276 12004076 12205091 17339318 10823831 11226425 21602890 16862177 15611064 12351678 16140212 11865071 26037477 16611863 10973499 23401859 25361009 11331613 18305400 25438054 14691445 17047048 12538644 22932900 18985005 26735336 21358672 18323857 10878807 19147576 16511565 17973296 23413029 24316222 11986208 12808024 12464182 23318261 22369643 19940151 15721254 20724477 21335603 16391536 23387829 18694926 26743088 14556007 18264140 10353251 15082527 11358837 11292862 11566883 12050673 19123984 17558023 27281823 15805242 11641274 25500545 34174286 24899725 12606543 32535973 17132228 24015760 12086861 11504942 35589690 26215701 22351759 12925778 18222538 17986458 14600153 10944113 23580587 26611735 18426857 20049704
HIF1A PGK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16585195 8089148 8702901
ESR1 PTMA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10938099 12149645 11459795
MAVS TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22901541 19893624 17020950 18818105 21200404 16306936 18207245 19546225 22844514 22792062 19193783 34610835 16858409
CSNK2A1 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21930781 17289674
ESR1 CARM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14631847 12498683 11010967 14675539
PHB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15140878 17932104 26052702 10938099 12943695
CSNK2A1 RANGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16428860 18669648
CSNK2A1 PDCD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 26077467 19616514 28051100
CSNK2A1 MAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10448092
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153
CSNK2A1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12700239 12432063
CSNK2A1 PIN4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12860119
ESR1 CYP1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16972788 16010691 17511620 15858227 15837795 20716622 22837390
YWHAZ YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501