RUNX1
|
BLK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10455134
14970218
|
RUNX1
|
BLK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10455134
|
PAX5
|
BLK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10455134
|
CEBPG
|
APOA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8175747
15109267
|
PTPN6
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10660620
6671678
|
FYN
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9694876
7737275
|
LYN
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9209406
8400282
|
LYN
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9209406
8400282
|
TP53
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15230856
8732672
|
TP53
|
GSK3B
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5216887
14744935
|
SYVN1
|
TP53
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17170702
5219455
|
IGHM
|
UBQLN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
YWHAQ
|
UBQLN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
YWHAQ
|
KRT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
PTPN6
|
CD79B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
7539038
|
SOS1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
NOTCH1
|
SOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17537801
|
PAX5
|
CD19
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15676205
|
CD79A
|
FN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6491104
18243143
|
RUNX1
|
CD79A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20385820
15361869
|
SH3KBP1
|
BLNK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8287480
21822214
|
PAX5
|
CD79A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15676205
|
SATB2
|
IGHM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14701874
|
PAX5
|
VPREB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9079818
1730258
|
KRT9
|
YWHAQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
CRK
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
LYN
|
CD19
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
10933394
7589101
15187135
7568175
|
1433T
|
TIAM1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SNX27
|
IGHM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SNX27
|
APOA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
1433T
|
HBB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
PATL1
|
IGHM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
DDX31
|
APOA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
1433T
|
IGHM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
DDX31
|
IGHM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IGHM
|
SE1L1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
18314878
19204006
|
DDX31
|
IGKC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CD79B
|
CD79A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8656670
9531288
1591006
12886015
|
GSK3B
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
BLNK
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
LYN
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
PTPN6
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
BLNK
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
CD22
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
RBPJ
|
NOTCH1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
8176976
21475249
|
SH3GL2
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
LYN
|
CD22
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10748054
8647200
10228003
|
SE1L1
|
SYVN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21454652
31477895
24807418
26424800
28827405
29496332
22119785
18502753
24366871
21903092
32614325
18711132
23356641
18264092
16186509
23867461
26471130
|
BLNK
|
CD79A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11909947
21822214
11449366
|
RBPJ
|
GADD45A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
IGHM
|
GADD45A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
GADD45A
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
GRB2
|
CD22
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10748054
11551923
|
FN1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18624398
19738201
|
FYN
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7499280
9344857
|
IGKC
|
LYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9547345
9601638
9480991
|
IGHM
|
LYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9547345
9601638
9480991
|
LYN
|
CD79A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9547345
9601638
9480991
|
LYN
|
CD79B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9547345
9601638
9480991
|
LYN
|
CD22
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9547345
9601638
9480991
|
UFD1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
TK1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
TP53
|
RBPJ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
19836055
24254977
26302407
|
TP53
|
RBPJ
|
â—¼ PROTEIN_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
19836055
24254977
26302407
|
PAX5
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8521821
22105368
21319196
|
TP53
|
KRT9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24492005
21617703
22466965
|
TP53
|
SYVN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16980608
|
IGHM
|
MAP3K20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
FN1
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16581250
10777559
12640026
|
IGKC
|
SYK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
7517665
8657103
15161916
|
IGHM
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
23836650
7618087
9890995
|
CD79A
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
23836650
7618087
9890995
|
IGKC
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
23836650
7618087
9890995
|
PTPN6
|
CD79B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
23836650
7618087
9890995
|
FYN
|
GSK3B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17607942
15676027
15652488
|
RBPJ
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
GSK3B
|
IGHM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
IGHM
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
SMN1
|
IGHM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MAPKAPK3
|
IGHM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
IGHM
|
UFD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
IGHM
|
TK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
GRB2
|
SOS1
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
23452850
|
SOS1
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
17474147
16713569
9856337
|
SOS1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
5220480
7642581
|
BLNK
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16189514
9697839
16912232
10820378
9705962
21822214
10556826
11449366
|
CRK
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
8810325
10962563
8662907
19380743
10970810
|
SOS1
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
25241761
31980649
8810325
17474147
8943292
33961781
19380743
32203420
|
SEL1L
|
SYVN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
NOTCH1
|
RBPJ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
GRB2
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
IGKC
|
BLK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
12453414
8306975
7524079
1702903
7927516
7592958
7688784
|
CD79B
|
BLK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
12453414
8306975
7524079
1702903
7927516
7592958
7688784
|
IGHM
|
BLK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
12453414
8306975
7524079
1702903
7927516
7592958
7688784
|
CD79A
|
BLK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
12453414
8306975
7524079
1702903
7927516
7592958
7688784
|
PAX5
|
BLK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9660839
10553071
10455134
8759736
14594818
8195169
18697940
|
TP53
|
GADD45A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
10749144
22801474
11221850
15031557
22262183
10321740
17700520
11420680
10094833
23114628
8892753
23948959
9405685
21394211
9931282
10435630
12007564
15721278
17440969
23576563
9566896
9233781
21836608
21245169
15186775
17063488
9154806
10327059
9191059
17344317
9519881
20797428
18350249
7624148
10566557
17084916
16714289
20840860
15735726
12806965
18225552
16581545
|
TP53
|
GADD45A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16990795
15603758
14627995
|
SYK
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
IGKC
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
IGHM
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
CD79A
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
CD79B
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
GRB2
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
GRB2
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
SOS1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
28514442
16520382
31980649
32062451
8493579
21988832
14679214
7510700
7514169
21706016
10319320
32203420
9872323
9797459
34407391
16906159
10716926
12577067
8810325
7629168
11960376
7664271
8626525
15192046
7629138
11997436
8943292
10207103
8695800
10570290
10025673
8112292
11726515
8816480
20473329
7559490
7773779
9447984
19380743
7642581
7527391
9716598
9344843
10477741
16713569
19323566
7516467
17474147
9569023
8188688
16893902
11964172
9478994
33961781
8479541
28166272
9009162
|
GRB2
|
SYK
|
â—¼ SHARES_COMPLEX
|
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
GRB2
|
CRK
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
FYN
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9822663
15886116
10849438
12670394
|
GRB2
|
SYK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
GRB2
|
FYN
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
BLNK
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
21822214
11449366
10820378
16912232
9697839
16189514
10556826
9705962
|
SYK
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11964172
16189514
22267732
10747947
|
GRB2
|
SOS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
145.0
|
1.0
|
Omnipath
|
9544989
9872323
7642581
15746962
11726515
8621483
23334917
16520382
11997436
21706016
10359574
8950973
7664271
16713569
16893902
16906159
21988832
19323566
9009162
10716926
11964172
7629168
9815779
10592173
9716598
8647802
28166272
7773778
7773779
18778683
8188688
10319320
8810325
9344843
23452850
11960376
8816480
10025673
7510700
8940013
12955078
9697839
12345678
10477741
8493579
8943292
12577067
7862167
9199344
8112292
7898932
10207103
8695800
19531499
10570290
7760801
20005866
19380743
9447984
8235613
8479540
7527391
14679214
8479541
17474147
7514169
7629138
|
LYN
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
9820500
24129562
10022120
18818202
21469132
24607955
18083107
17389395
19285079
11536198
10592173
25045209
7797565
11380624
9857068
7513017
30923129
8621719
10477689
7831290
15701717
27258042
19369195
28082678
8666899
9535867
8657103
14871838
|
LYN
|
CD79B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9531288
17570479
12453414
8077654
|
LYN
|
CD19
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
15187135
10706702
7568175
25673924
7589101
10201980
16497976
10933394
9190913
15212693
11809733
|
LYN
|
CD22
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17145710
32323266
10228003
8647200
9586639
|
LYN
|
CD79A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
1506682
17570479
9531288
10748115
8183901
|
LYN
|
PTPN6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
19171907
11042209
8692915
14699166
22624718
19690332
12468540
10574931
17570479
18083107
14757045
8114715
10488096
28811476
|
TP53
|
ARID3A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12136662
22172947
18431400
12692263
|
GSK3B
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
23840442
12064478
11709713
9372954
11483158
16552184
17570479
14744935
16713569
21929745
12048243
21900206
|
TP53
|
ARID3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12136662
15017387
18431400
|
IGKC
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
18818202
7592958
7538118
8163536
|
IGHM
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
18818202
7592958
7538118
8163536
|
SYK
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
SYK
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
CD79A
|
SYK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
Reactome
|
16849466
21469132
18052078
18818202
18006696
10648173
8163536
7538118
|
CD79B
|
SYK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
Reactome
|
16849466
21469132
18052078
18818202
18006696
10648173
8163536
7538118
|
IGHM
|
SYK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
Reactome
|
16849466
21469132
18052078
18818202
18006696
10648173
8163536
7538118
|
SYK
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
10358164
11907067
12524384
14568985
15536084
17101731
19909365
20150200015
21149606
21378271
21910624
23609447
8189062
8226994
9000133
9295024
9314552
9396765
9632805
9763615
|
FYN
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
7797565
7513017
17570479
10477689
9535867
16713569
|
PTPN6
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
12763134
11356834
10592173
16189514
10458769
10072516
10747947
|
SYK
|
BLNK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
18369315
12456653
9697839
16189514
10981967
21047529
|
SYK
|
CD79B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7538118
12453414
|
SYK
|
CD79A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
30465710
12453414
7538118
7500027
20940318
|
PTPN6
|
CD79A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
7539038
|
PTPN6
|
BLNK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11356834
10903736
15588985
16189514
|
IGHM
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
12453414
8306975
7524079
1702903
7927516
7592958
7688784
|
FN1
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
IGKC
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
12453414
8306975
7524079
1702903
7927516
7592958
7688784
|
FYN
|
SH3KBP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
17350651
23052211
23506116
16529723
|
FYN
|
CD79A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
12453414
8306975
7524079
1702903
7927516
7592958
7688784
|
FYN
|
CD79B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
12453414
8306975
7524079
1702903
7927516
7592958
7688784
|
FYN
|
SOS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17474147
16713569
9856337
|
FYN
|
CD79A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9531288
17570479
8183901
1506682
|
FYN
|
CD79B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9531288
8077654
|
RBPJ
|
NOTCH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22143792
11404076
12700242
24113181
|
GSK3B
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
16944320
15465828
12123574
11967263
14663202
8524413
21828089
16713569
9832503
15020233
|
NOTCH1
|
RBPJ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
51.0
|
1.0
|
Omnipath
|
23022380
16530044
22143792
25609649
26033182
16530045
21475249
8749394
23103515
16713569
22325781
19907488
23331499
21071413
26496610
18988627
22100894
10637481
26186194
21820430
12644465
10713164
17636029
9032325
12370315
11997524
11390662
19165418
19800882
20028974
30967258
9111040
17284587
17526737
|
SYVN1
|
SEL1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
ACSN
|
12847084
16186509
18199748
18360008
19509052
|
SYVN1
|
SEL1L
|
â—¼ SHARES_COMPLEX
|
|
|
5.0
|
1.0
|
ACSN
|
12847084
16186509
18199748
18360008
19509052
|
PAX5
|
CD19
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
7532151
12907641
20208555
7541987
8639790
9722295
1375324
10666449
15163413
11359826
17513763
18617575
|
IGKC
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
CD79A
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
CD79B
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
IGHM
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
SOS1
|
BLNK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11071869
22262777
9697839
21822214
|
SOS1
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11071869
22262777
9697839
21822214
|
IGKC
|
BLNK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
IGHM
|
BLNK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
CD79B
|
BLNK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
CD79A
|
BLNK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
IGHM
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
CD79B
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
IGKC
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
CD79A
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
CD79A
|
CD22
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
7706301
7561031
8475064
11994425
|
IGKC
|
CD22
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
7706301
7561031
8475064
11994425
|
IGHM
|
CD22
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
7706301
7561031
8475064
11994425
|
CD22
|
CD79B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
7706301
7561031
8475064
11994425
|
IGHM
|
CD79B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
7514267
2269333
1375264
1401917
|
IGKC
|
CD79B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
7514267
2269333
1375264
1401917
|
IGHM
|
CD79A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
7514267
2269333
1375264
1401917
|
IGKC
|
CD79A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
7514267
2269333
1375264
1401917
|
PAX5
|
CD79A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
14500810
19616560
18641300
10435576
11779502
15361869
9545244
9743352
8804314
12446773
12612069
|