Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HSP90AA1 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9038169 9151685
HSP90AA1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
HSP90AA1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0908908106 19805354
HIF1A HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14726529 20068160
TNF ICAM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21474822 22846676
HOOK2 KAT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KAT7 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212855 10930412
KAT7 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19307749 19411311
KAT7 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16547255 17532302
HIF1A LRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020 21454812
USF1 MAPK14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18817855 12970752
MAPK11 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23602568 21900206
YWHAQ MDM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16511560 5218386
MDM4 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 19521340 7290688
TP53 PARK7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23447676 23149933
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
TP53 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
TP53 LAMA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22103682 8291914
TP53 TFAP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18980971 16636674
TP53 PRKCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10614633 9895308
TP53 FASLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10969818
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
TP53 HGF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9841917
YWHAQ EIF4A3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
FLI1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25108845 23108091
CEBPD CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12145301 15829559
ESR1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20404154 17932106
HIF1A IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17504662 15723200
STAT5A IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18768844 23797738
SP1 IL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18843277
HBB HBA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HPX HBA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20430887 8855948
HBA2 PTEN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HBB HBA2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
ITGB2 ITGAL â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 19161977 21270398
ITGB2 ITGAL â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 19161977 21270398
KLF1 BCL11A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20676099 20676097
KLF1 KLF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18687676
KLF1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12556498 18523154
KLF1 AHSP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17069580 16705186
FLI1 KLF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12556498
KLF1 FLI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12556498
F2RL1 CD81 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
ETV6 CR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10597047 12220513
ETV6 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17606295 19829305
VIM GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
VIM KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JUN HBZ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24336657 15592508
TFAP2A HGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10860846
STAT5A MYD88 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7567467
TFCP2 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10586050 23220634
ZFPM1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21646796 11971000
HMGA1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15710911 7629508
TFAP2A IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16616959 9480831
HIF1A PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18340011 19648120
PTEN SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12804776
CXCL8 ACKR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8248172 12956774
TBP JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17074809 21106530
HIF1A JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15794924 19828020
ESR2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10037443
JUN AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 11192249
JUN PRKCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20444941 7841543
JUN SELE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9103451 9317150
JUN HP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12384935 22243239
JUN CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17965828 20506344
KLF8 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10756197
SP1 KLF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18353772
MET FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28536399 15911745
AR IL18 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15178407 20610535
TLR4 CD36 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20037584 7685021
POU2F1 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16352814 8663022
SPI1 CD163 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10725797
SPI1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18076876 9028962
SPI1 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24503536 19423615
SPI1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9292515 12027437
SPI1 CSF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
HSP90AB1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HIF1A SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934262 15780936
HIF1A NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15699159
TBP EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15169879 9679659
EGF MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20178463 17081983
SP1 EPAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17024177 5219187
KLF11 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15531587 15024015
SP1 IL12A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12576336 14568984
SP1 VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11133225 7499419
SP1 PRKCB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12105191 20179320
SP1 CD163 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10725797
SP1 GATA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18195733 7858429
SP1 NPPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20874724 9295358
SP1 FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15158147 19302822
SP1 SMARCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18243132
AR FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11690559 20610535
EPAS1 FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17324924 18625704
ESR2 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16549430 17261755
EHMT2 LMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LMO2 GYPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14749362 18844071
MAPK11 PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCA HDAC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8307255 21952047
TFAP2A PRKCA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12269829
USF1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12663664 15563837
AR CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24810056 20610535
TFAP2A CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10652362
NCL MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10660576
F2RL1 GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9349532 31160049
GNAQ PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
GNAQ PLCB4 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
GNAQ PLCB2 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
GNAQ PLCB3 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
HSP90AB1 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9038169 9151685
HSP90AB1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21730179 1105160108
YWHAQ HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSPA8 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9038169 9151685
ESR1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
POU2F1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18000219 20215511
TFCP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21655924 19966177
ESR1 EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10432218 18414489
ESR1 YWHAQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22329840
ESR1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
ESR1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14695898 18252963
ESR1 TGFB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12580758 11159847
MYB AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12096342 18945670
AR SMARCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16373397 20610535
AR ESR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11371645 20610535
PECAM1 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GATA1 PECAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8955189 9028949
PLCB2 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
PLCB2 PLCB4 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
PLCB2 PLCB3 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
TBP NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 9649342
PRKCB MAPK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8626698 16189514
NR3C1 HP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20155810 9169415
HPX HBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20430887 8855948
SELENOT HBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SMARCA1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10535918 9778250
KLF2 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21610079 7565748
NR2F2 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath
BCHE KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
POU2F1 H2BC11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12887926
UPF3B UPF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12718880 5216341
HP APOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19758344 7258755
ZFPM1 GATA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000123 19513100
PLCB4 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
PLCB3 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
SDC2 SDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18093920 0708909105
SDC1 SDC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18093920 0708909105
LAMP2 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9038169 9151685
KLF2 EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16049344 20628425
NR2F2 APOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9580705 1639815
PLCB3 PLCB4 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
HIF1A HSP90AB1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
MYD88 TLR2 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
COPS3 HSP90AA1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
GATA1 SPI1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10364157 12202480
ESR1 PRS8 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14702340 8598193
MDM4 HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 MIF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
PARK7 MIF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
PNKP HBA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PNKP HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CD81 APOA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32900848 30024968
MYD88 TLR9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15107846 21911421
CFTR FAS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
ESR1 FAS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 25604459
VCAM1 FAS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
HIF1A SP1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
SP1 EPAS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22402494 17024177
ESR1 HSP7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27483141 9774640 20308691 19805454 21182203 15538384 21182205 16037132
RBM8A SMG7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20371770 16452507
DHRS2 HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
1433T HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
K1467 HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MK06 HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LPAR2 HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GRID1 HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GTR14 HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HSP7C HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MSL2 HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SEMG2 HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PLXB1 HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GSTT1 HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BMP5 HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PLPL1 HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
PRS8 HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
H2B1J HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
REN3A APOA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MSL2 HBA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 PRS8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 26337389
REN3A HBA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 HSP7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
HSP7C HBA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SDC1 DHRS2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433T DMWD â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433T IGHM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 HBA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
MK06 HBA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GTR14 HBA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GSTT1 HBA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PLXB1 HBA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 HBAZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
MK06 HPT â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SDC2 DHRS2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AKT1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
HSP90AB1 NR3C1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
GNAQ PLCB3 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
GATA1 ZFPM1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
CSN3 HBB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DACH1 HBB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
AKT1 HSP7C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24462114 31980649 16027165
HDAC6 CFTR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31501480 22069321 14675537
REN3A HBB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 11163187 33961781 21145460
TMM92 HBB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CYTIP HBB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NDUF5 HBB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ASPG HBB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
GDPD1 HBB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
JOS2 HBB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PGPI HBB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MGT4B HBB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HBB HPT â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 7378053
GDPD1 APOA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PGPI GTF2I â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HSP7C 1433T â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27684187 15324660
GDPD1 KNG1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ASPG HBA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PGPI HBA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
GDPD1 HBA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NDUF5 HBA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
GDPD1 HPT â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
AKT1 MAPK14 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
ICAM1 ITGB2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
AHSP HBA2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
GTF2I USF1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MDM4 1433T â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16511560 17110929 29523541 18356162
TGFB2 TGFB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27684187 11483955 33961781 11157754
ESR1 EHMT2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21984853 31527615
ESR2 HSP7C â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 21951318
HBAZ HBB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32296183 6683087 16189514 11747442 11159543 25502805
APOA1 APOB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28183703 7592581 19164805
MDM4 YWHAQ â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
HSP90AB1 HSPA8 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
HBA2 HBQ1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
HIF1A JUN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25879517 19738058 11739718
SPI1 JUN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12091339 9681824
SPI1 TBP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11593411 8434021
CFTR HSP7C â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11146634 16857740 17110338 10666020 23990462 29924966 26618866 21697503 15611333 17272822 10982807 10075921
PTEN TP53 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
AKT1 PTEN â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
JUN SP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
UPF2 UPF3A â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
HBM HBZ â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
AKT1 PTEN â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12297295 19903340 12077256 28628118 20605778 28205554 10866658 20596030
AKT1 FAS â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25640309 31980649
HBA2 HBB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
HBA2 HP â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HBA1 HP â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
POU2F1 SP1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
DACH1 JUN â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17182846 25609649 16980615
HDAC6 MYD88 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31268348 29281743 20837465
HMGA1 JUN â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10357819 10428834
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
1433T ESR2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29509190 11266503
ESR2 PRS8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29509190 25604459 15604093
HBB HP â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
MK06 APOA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21900206 33961781 28514442
HPT APOA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 19758344 15533931
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
FAS FASLG â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AR SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AKT1 AR â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ITGAL ITGB2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CFTR HSPA8 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HSPA8 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MAPK14 TP53 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
AHSP HBA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12192002 15550245 25156257
FGF2 SDC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 16982797 33961781 19802384
FGF2 SDC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 16982797 33961781
TBP TP53 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ESR1 HSPA8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HDAC6 HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
AR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
USF1 USF2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MYD88 TLR2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17126326 15107846 16482509 16293622 29990310
TBP JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 7848298 7685215 16713569 16055710
SP1 JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25879517 10506225 16713569 33572115 16478997 17215518
JUN ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17317669 11477071 16713569 23747343
HIF1A SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12228247 17024177 17418410 15780936
PRS8 SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10816420 18572193 16713569
HMGA1 SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20335021 12665574
PLCB1 GNAQ â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16754659 12193606 11753430
1433T ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11266503 33731348 31527615
TBP ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9259327 16713569 31527615 11595744
GTF2I USF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21653943 16943425 9384587 1961251
GATA1 LMO2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
NR1I2 COPS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
VIM KAT7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KAT7 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10542243 24513290 11923478
HPX LRP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15947085 496916 8424694
MAPK11 MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 MAPK14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11437382 15132979 14570892
SP1 MIF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21087445 18034423
HSPA8 PARK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
NR3C1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15956716 15289446 16557033
TP53 RBPJ â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 19836055 24254977 26302407
TP53 RBPJ â—¼   PROTEIN_INTERACTION 3.0 0.9 ACSN 19836055 24254977 26302407
TP53 HP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16199185 8857671 22243239
TP53 FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8090761 10029407
TP53 H2BC11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21617703 16980608
TP53 HGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17216187 18431400 9023107
TP53 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22804246 23666675 20406462
NR3C1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
MSL2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19788416 19033443
TP53 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31027880 18431400
TP53 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
HIF1A CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27271610 17474992
JUN IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15699140 25567680 28100679
CEBPD IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16871431 16413748 12847250
HBA2 CD163 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11196644 16189277 17008602
HBA2 CYB5R4 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 3.0 0.9 Reactome 15858218 10611283 15131110
HBA2 CYB5RL â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 3.0 0.9 Reactome 15858218 10611283 15131110
HBA2 CYB5R1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 3.0 0.9 Reactome 15858218 10611283 15131110
HBA2 CYB5R2 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 3.0 0.9 Reactome 15858218 10611283 15131110
HBB CYB5R1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 3.0 0.9 Reactome 15858218 10611283 15131110
HIF1A ITGB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20517715 15235127
MYB KLF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20686118
GATA1 KLF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20564185 8195185 18487511
VIM HSPA8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
SP1 HBZ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22696638 2403638
MET HGF â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17804794 18593464 15167892 1846706 28628118 1655405 19433454 20624990 18495663 16537482 22897854 28205554 17981115 8380735
SPI1 HGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22472882 9315634 9223667
IL1B MYD88 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17507369 17890055 9430229
CTCF MYD88 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
USF1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8900159 21050451
AR CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17617741 20610535 22040886
JUN VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9468519 16271621
JUN IL12A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16600913 22904313
JUN NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 7823959 8733011
SP1 KLF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18353772
TFAP2A FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11310795 7528667
NR3C1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15802531 15590983 15289452
SPI1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16263717
USF2 THBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20410211 15184388
THBS1 TGFB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22943793 8349738 21900405
THBS1 TGFB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22943793 8349738 21900405
HIF1A TGFB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10831118 16611863
STAT5A EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18996136 12697691 21617857
SP1 EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14741200 22138754
SP1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7559553
SP1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12039077 14962081 15249123
SP1 HPR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12088866
NR3C1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18174358 24500711 27371733
MYB LMO2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20686118
CEBPD CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499410
HSPA8 CFTR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSPA8 IFT88 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
PCNT HSPA8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSPA8 CETN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSPA8 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
PLIN3 HSPA8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
RNASE1 HSPA8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSPA8 PLIN2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSPA8 ARL13B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
TFAP2A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10497269 19458056 9850080
USF2 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15042619
AR TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 9238003
AR NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315100 15219414 20610535
AR IL12A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26939703 23941877 20610535
AR MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20610535 20946682 17283128
NR3C1 NPPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1835978 8780246 9171949
REN3A RBM8A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11546874 16601204 11546873
TBP HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7567458 8370527 1559609
GATA1 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK6 APOA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
USF2 USF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18817855 28514442 16943425 17846119 17353931 21653943 9053857 26496610 33961781 8576131 15014447 19303849
USF1 HP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17467197 16396632 18167349
ESR2 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
TFAP2A NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9015328 7794935
NR3C1 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 8878484 9528750
HBB CD163 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11196644 16189277 17008602
GTF2I HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16943425 17970752 12582249
HBB CYB5RL â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 3.0 0.9 Reactome 15858218 10611283 15131110
HBB CYB5R2 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 3.0 0.9 Reactome 15858218 10611283 15131110
HBB CYB5R4 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 3.0 0.9 Reactome 15858218 10611283 15131110
HP HBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9315856 7378053
NR1I2 KLF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
GATA1 FLI1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 10364157 12556498 12724402
GATA1 GYPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1396593 8634425
GATA1 ZFPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11675338 9230307 21853041
IL12B IL12A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10899108 10779781 7527811
EPO STAT5A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9837784 22509308 8861946
MYB DHRS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15105423 20547751
HP CD163 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11196644 16189277 17008602
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
UPF3B RBM8A â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 12718880 5216341
SMG6 UPF1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
UPF1 UPF3B â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
HIF1A HSP90AA1 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
PLXB1 MET â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 15184888 12198496 22404908
MYD88 TLR4 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
HSP90AA1 NR3C1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
CD40 CD40LG â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ESR1 NR2F2 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
AHSP HBA1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
UPF2 UPF1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17469741 5219891
IL12A IL12B â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
TP53 MDM4 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 7290688 19521340
TP53 MDM4 â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 7290688 19521340
TLR4 MYD88 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17126326 15107846 10952994 17258210 18221795 20048342 15728506 33052227 12646618 11743586 21911421 21829704
HBA HBB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32296183 16189514 6683087 1552945 12122004 11724557 10390349 8980683 9441940 29997244 30833564 28665412 9830011 6644819 15835899 16169070 10930828 9894000
ICAM1 ITGAL â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
EIF4A3 UPF3B â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RBM8A UPF1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HBB HBZ â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PABPC1 RBM8A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RBM8A UPF2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RBM8A SMG7 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
EIF4A3 UPF1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SMG7 UPF1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF4A3 RBM8A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
HBA1 HBB â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MDM4 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
UPF1 UPF2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RBM8A UPF3B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BACH1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15175654 14660636 16824198 8887638 15809329
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
PRKCG HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 26804907 24117238
HDAC6 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19158084 18591380 18266962
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
HSP90AA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 1525041 19805354 20048054 15861399 17974989 26342197 17353003 26196320 16713569 27903893 1540595 21157430 19706771
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
HSP90AA1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 16131566 8089152 10903152 26804907 31467278 8645634 15916966 24949977 21511880 19875381 9334248 12093808 16189514 20195357 24462205 10066374 14987994 8898375 8621522 8139547
IFNG ICAM1 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
IL18 ICAM1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10679398 11592085 14504095 14662834 15099563 15802534 26885855 27048821 27066895 9469432
IL10 ICAM1 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10433356 10542212 10623821 10925299 11207245 11438547 11875494 12193690 12811837 12818165 14607900 15282297 15579430 15749903 15833879 16200688 16424049 16713974 17404308 17485448 20184663 20435894 20547845 21115385 21191065 21220452 23124025 23508573 24378531 26755705 9834059
TFAP2A ICAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11060030 12952965 8962096 11751911
JUN ICAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11356008 12832416 9218873 20459645
ICAM1 ITGAL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11786177 16595626 16354667 12526797 23602662 11279101 16189514 14507735
ICAM1 ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 4062888 12208882 11279101 16189514 10352278 20187292 14507735 7642561
KAT7 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10930412 16713569
PRKCA LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15272003
MAPK14 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 57.0 1.0 Omnipath 21675959 26247731 20213747 17535811 20506250 15657900 9315650 15642743 19413330 11283254 22975381 10581258 16083285 1088347 21614932 16393692 10884347 21050851 16552184 10747897 15187187 17906639 25789565 15140942 11258706 24818748 19436832 10781582 10212189 17172861 10348343 11078726 11274345
MAPK14 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23216744 22431515 12138194 15879307
MAPK14 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 30644418 24424504 21820033 16282370
MAPK14 USF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 16622840 11532965 21873430 19389701
MAPK14 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 25847991 12351702 28582465 31974640 20047289 22911818 19841061 12000743 15817653 20660302 17570479 22401993 17440046 17185395 24024586 19812390
MAPK14 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12475989 17689131 17570479 25483191
TP53 MDM4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16492744 18172009 21750655 20036872 21422812 17510313 9926934 18336191 19521340 20372076 10469568 20080970 22290440 21394211 23474762
AKT1 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16163388 18356162 16511560
MDM4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 74.0 1.0 Omnipath 25609649 18677113 28487147 24445145 30045945 20515689 26148237 22266850 11528400 19521340 21088494 16713569 15916963 9226370 12874296 21925390 16024788 25825738 24667498 16227609 24127580 8895579 20174603 18485870 12963717 15604276 25464845 12370303 10608892 23028042 25961923 26186194 17110929 22374672 26876197 17301054 23671280 21965653 17875722 22807444 10075736 19305137 17080083 29023092 27114532 20724842 10827196 19255450 24659749 28035068 23946421 20705607 19075013 21075307 12393902 11223036
TLR4 MIF â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11672593 11964313 12032143 12803886 12811837 16267105
TNF MIF â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10754326 10878343 10925299 10952726 11112697 11438547 11875494 12646658 12782713 12803886 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15465827 15644117 15699106 16283355 16713974 16878026 17404308 17485448 17916596 18490733 18633355 19411070 20038811 20184663 20435894 20861157 21133840 21411734 21826665 22595692 22955274 23170255 23390297 23430059 23508573 23510023 23567181 23769623 24092389 24378531 26201938 7594497 8195715 8910423 9637476
IFNG MIF â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
HIF1A MIF â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10804084 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824
MIF SPI1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10878343 12782713 12803886 16283355 18490733 20861157 23390297 8195715 9637476
MIF IL10 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10878343 12782713 12803886 15749884 16283355 16713974 17404308 18490733 20547845 20861157 23390297 8195715 9637476
TNF MIF â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10754326 10878343 10925299 10952726 11112697 11438547 11875494 12646658 12782713 12803886 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15465827 15644117 15699106 16283355 16713974 16878026 17404308 17485448 17916596 18490733 18633355 19411070 20038811 20184663 20435894 20861157 21133840 21411734 21826665 22595692 22955274 23170255 23390297 23430059 23508573 23510023 23567181 23769623 24092389 24378531 26201938 7594497 8195715 8910423 9637476
HIF1A MIF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19828020 20606117 17998063 20727156 16854377
SP1 MKI67 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21611785 22890831 22125028 20963645
TP53 MKI67 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21611785 11713584 10365096 15217513 16258956 14675138
AR PARK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12612053 17510388
HIF1A TNF â—¼   ENZYMATIC_REACTION ✅ 28.0 1.0 ACSN 10754326 10804084 10952726 11875494 12907458 14660645 15465827 15644117 16110315 16127144 16878026 17404308 17485448 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 23390297 24006507 25043024 25103413 25732824 7594497
IL6 TNF â—¼   DOWN_REGULATES ✅ - 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
ESR1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23733894 15334655 16483936 12237295 20664923
SP1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 23733894 12759366 27030318 22534375 7649977 12509451 12378384 15175554 18357389 10829018 11390427 17897957 18218727 8258705 12560487 17047073 21320120 7918637 16847329 10559188 18930140 20068037 1618817 21784970 10688670 10913190 17307735 18467438 21411747 11500175 20221720 20701940
SPI1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18802049 10748079 19646961 8998076 18408586 18357389 25567680
HIF1A TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21386799 17451682 15604270 17548584 17884817 15925386 22320863 23359428 23085511 19766100 16007254 12479793
JUN TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 12759366 11087751 7935377 21059644 16881863 24548427 12509451 9826775 10318823 8998076 18408586 15546613 20164416 7896795 9211933 10952728 9566900 23583459 10748079 24009130 10954918 10754326 9813054 10837498 9988757 11739517 16365438 19285436 16199883 8816436 10551799 8552071 9160673 11490006 21098092 16483936 10688670 10913190 16888805 9030359 25567680 9760243
CEBPD TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10796884 15284209 10629048 22514649 20220144
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
JUN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22859294 17321721 20697347 10348347 12963547 10072388 22353755 18604200
TP53 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15052775 15284248 21478269
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
TP53 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12732139 10618379 22264233 23706820 14514686 8183578 14761612 16138117 18593586 23063463 8119773
TP53 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10101800 12788915 15580300 16317104 16322229 14719118 16557594 20797428 11103825 19615968 7539102 12447615 12944915 12963547 11313989 16951143 9841917
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
TP53 FASLG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17196791 9889415 20393600 9841917
TP53 THBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12609716 10719731 10101800 24195060 10029407 16406676 19826414 9833779 12719977 9017002 22028325 10224095 9849855 7521539
TP53 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22957312 15843377 12917634 21637289 17344317 12839924 11545734 18172008 19173293 20554748 19079342 14984207
PRKCA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18812399 9935181 15659650 9315650 19933256 16713569 9571186 1454855
MAPK11 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15187187 17145710 19436832 15140942 10212189 20506250 21614932 16393692 17254968 11274345
TP53 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21336307 18431400 18339852 12620407 17409411 18172008 17823410 16713569 21518799 21483453
TP53 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23443559 18431400 11707401 22939624
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
UPF2 UPF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 17145710 19478851 11544179 18256688 11073994 19150429 17469741 20371770 24778252 16452507 11163187 16086026 19503078 18066079 12723973 16488880 19556969 12417715 21145460 19417104 14527413
UPF3B UPF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 18066079 12723973 11163187 19417104
MYD88 CCL2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
JUN CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19162185 18024959 18443042 14752027 22674286 23583295 19299558 12667961 10918580 19371341 26554515
SP1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10792620 10644332 17255531 8630731 10636866 16847329 10657660 23349788 12787135 12488502 12682245 25108845 8051410
MYD88 IL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IFNG IL10 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
IL10 THBS1 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10433356 10542212 10623821 10925299 11207245 11438547 11875494 12193690 12811837 12818165 14607900 15282297 15579430 15749903 15833879 16200688 16424049 16713974 17404308 17485448 20184663 20435894 20547845 21115385 21191065 21220452 23124025 23508573 24378531 26755705 9834059
IL10 CD163 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10433356 10542212 10623821 10925299 11207245 11438547 11875494 12193690 12811837 12818165 14607900 15282297 15579430 15749903 15833879 16200688 16424049 16713974 17404308 17485448 20184663 20435894 20547845 21115385 21191065 21220452 23124025 23508573 24378531 26755705 9834059
SP1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20072143 22469463 12493739 17376198 12847250 19564345 10903771 10657644 18843277 21309719 10861063 16871431 19307576 11278848 22940633 16413748 17202341 15972681
SPI1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20072143 19592658 18843277 12424622 25567680
TFCP2 HBA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 2233727 20421208 18629613 8157699 9753426 10491335
AHSP HBA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 25156257 18179859 15550245 12192002
SPI1 ITGB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 7559529 16735694 9582348 8670251 10542290 7846055 9295016
VCAM1 ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10438935
SPI1 ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7846055 15676205
HIF1A ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7539918 15235127 1823643 16716598 12829734 9159130 13130303 9746763 12080085 11566883 10403805 8943284 15451019 9278421 16887934
PRKCA ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11700305 12682249 17570479
KLF1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 12556498 9418858 10575545 20676097 10468560 11287616 10535918 19220418 9668528 8195185 21610079 10706605 8916973 14764531 21539536 8924208 8918890 9207479 7753194 11259590 10652365 7829533 8901569 7682653 10990462 15833715 21220744 19251649 9545245 11238130 9603943 9707565 9778250 15384985 9422764 16705186
GATA1 AHSP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16186125 21232177
ETV6 STAT5A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 31066629 17764812 19345670 23168613
SP1 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17663720 22227038 3419902 10777586 12771217
JUN VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7986748 14654785 2922288 16831196
AKT1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20856200
PRKCA VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 14762106 20058876 11895474 19007248 19415658 19691289 19291697 18669648 18767875 2500966 20068231 19144319 17287340 12761892 19664995 18212344
HGF MET â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 11290563 12649206 15059978 16212809 17145802 18633355 19631971 20303741 22763439 23402812 23667593 26366398 26819959 27474009 28475121 9242465
HGF MET â—¼   PROTEIN_INTERACTION 16.0 1.0 ACSN 11290563 12649206 15059978 16212809 17145802 18633355 19631971 20303741 22763439 23402812 23667593 26366398 26819959 27474009 28475121 9242465
FGF2 HGF â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11874475 18232728 18633355 18776941 19508171 19631971 21098712 22652804 23123598 25374926 9242465
SP1 HGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9223667 17967179 12482909
HGF MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 57.0 1.0 Omnipath 17145710 22897854 15167892 1655405 20624990 19433454 23331499 17804794 1846706 28475121 22001117 16537482 15218027 27147579 24362531 17667909 16397249 20178463 17981115 28534512 8380735 18495663 14685170
CD40LG CD40 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
CD40LG CD40 â—¼   PROTEIN_INTERACTION 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
CD40LG CD40 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 1280226 1374165 19426221 7516405 11163401 7543281 12324477 10647992 17183360
MYD88 IL18 â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 14504095 14660645 14662834 15099563 15802534 16878026 17704786 23681101 23811849 26885855 27048821 27066895 9469432
MYD88 IL18 â—¼   SHARES_COMPLEX 18.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 14504095 14660645 14662834 15099563 15802534 16878026 17704786 23681101 23811849 26885855 27048821 27066895 9469432
IFNG MYD88 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
MYD88 IL6 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
MYD88 IDO1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
TLR4 MYD88 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 22664090 19717524 20048342 21911421 9625770 17228323 17258210 11743586 15107846 15728506 12888566 21829704 18221795 10952994 17635639 17126326 12646618
TLR9 MYD88 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22664090 16410796 21911421 12791976 17417641 15107846
TLR2 MYD88 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 22673208 19717524 22664090 20348427 16893894 15107846 29990310 16798732 16482509 16293622 17126326
IFNG TLR4 â—¼   ENZYMATIC_REACTION ✅ 41.0 1.0 ACSN 10485906 11489965 11579131 11672593 11777960 11870632 11964313 12032143 12413632 12811837 12818165 14607900 15634932 15644117 15778339 15811952 15814715 16286920 16306937 16424049 16713974 16917499 17016554 17114424 17559085 1825141 18272812 19833085 20038811 20154735 20547845 20819927 21149606 21411734 23508573 24658051 26755705 2965306 6425450 9834059 9864217
IFNG TLR2 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10485906 11489965 11579131 11672593 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16267105 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
IFNG HIF1A â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
SP1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24019072 17023546 12576336 8756632 18793716 9503023
JUN IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 20006311 22123848 14734615 15187132 11943142 20304822 17556653 1314139 17105733 22413812 19265145 11801649 16713974 7759501 12836278 15522880 12626576 9558063 8756632 18641343 22351517
STAT5A IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12759422 7875295 7796811 15528362 9831114
SPI1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15345588 19502584 12130529 7814871 9545284 20585034
HIF1A IL6 â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10804084 15749903 16110315 16127144 16243976 16413922 17485448 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824 9743347
SPI1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15013752 23509362 18680724 19502584 25567680
CEBPD IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7821611 10748205 7680115 15158360 14600152 9528783 15486993
HIF1A IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17548584 20003295 21258402 15913932 18791496
AR IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12237244 8824277 19074897 11049111 17374439 11410519 20610535 19363165
JUN IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 26513016 10542237 21069809 15389813 15158360 20225236 12667961 20371366 20511231 20862675 8453101 10202034 18502099 10037779 8830832 19687301 21098092 25567680 20351184 17341596 11120852 21312239 24676671
NR3C1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19436110 8175711 27371733 11459775 8290595 21474440 2233715 1871124
PTEN AKT1 â—¼   DOWN_REGULATES ✅ - 22.0 1.0 ACSN 10753747 11747822 12040186 15721744 16288286 16982858 17218262 17409395 19440036 19847259 19945467 20609352 21084277 22179046 22465479 23732914 24030100 24254977 25364523 26597054 27328425 27572739
RBPJ PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17245125 19479935 24113181
AKT1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19903340 15987703 10790335 20596030 10592173 20605778 10866658 12077256 11035045 16107342 12297295
PTEN AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15205473 24480624
THBS1 TGFB1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10657674 11982756 14568985 14996710 21900405 22943793 8349738
USF1 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18955796 21389977 14757763 16457817 15983197 16488890
HIF1A TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16896927 17053163 15611046 19211927 21209004 21057546 21055290
USF2 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14757763 15184388 15983197 16488890
JUN TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8058069 16327802 16730810 23437118 8183578 16365456 22429882 23936544 15546613 10843986 16978906 23762330 7521696 8631909 12794825
SP1 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12186868 9580699 2808430 12615726 22415074 27974707 12138160 10964912 9242631 15178441 23437118 23936544 11114293 8325508 16714330 11278686 10212284 9837963 11054406 23806282 15979845
THBS1 TGFB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22943793 8349738 21900405 1550960
HIF1A CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17082639 19491109 17488804 21925595 23144021
JUN CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 18684922 16701870 24048734 14686613 24284797 15057743 12643600 17197543 11864912 10817569 12218154 22031759 17586662 10969814 19064995 12716652 27856305 25582859 17471497 22095787 16818736 23176534 14670967 18435575 16846747 19734226 16299055 14612204 18772138 19132242 12209633 15939312 16834785 11399048 11120852 25567680
ESR1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15208657 16029657 19440537 14991571 18669446 17932106
NR3C1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 24500711 27371733 15879558 19307749 15355994 21474440 1592440
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
SP1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20148354 8355696 8892460 1406636 19437621 9054614 17502875
NR3C1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20499359 8639160 2169353 9731701
JUN IL12B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15187114 15270850 14688340 25567680 11279072
JUN IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11306276 18566416 7935377 10226077 14686613 16365456 11145674 17283046 20463008 23608488 8133045 8798756 18789903 16729332
JUN EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16740983 1918021 22301113 21239258 12208352 21216243
JUN MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1527086 8670250 12475180
JUN FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9456251 10913304 10559225 11281649 11551904 23485603 23331079
JUN FASLG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18196534 9873041 9660938 14563113 9710625 11003676 19670268 10811113 9468493 15160330 15546613 12618758 11397794 10744679
JUN SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17283046 10411939 9178763 9988737
JUN EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15075211 15772294 19937979 15375216 10617690 18625220 15238218 7629150 8885243 12954631 10973489 16214953 14518567
JUN FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733515 12963547 10903433 19670268
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
AR JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11577103 11518798 9211894 8798722 16713569 9591784 17721441
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
JUN SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12393465 10411939 12091339
FASLG FAS â—¼   PHYSICAL_INTERACTION 53.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22075988 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
FASLG FAS â—¼   SHARES_COMPLEX 53.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22075988 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
SP1 FASLG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10075666 20617570 11254710 11053446 14563113 10754388 18293083 15659839 11970950 12655294 17192273 11745351 15173177 15004200 10671224
FASLG FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 17145710 8521815 9126929 1375228 1713127 14965271 21803845 9039262 11239407 25241761 9228058 15659383 12753742 7505205 12887920 15725726
SP1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10022897 9261184 22084312 9300785 10871852
SPI1 TLR4 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10734131 11672593 11964313 12032143 12803886 12811837 16283355 16418395 20510871
SPI1 TLR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16424218 10734131 17495427 24155397 20956019 18485892 16093364 16785240 11780066
SPI1 GATA1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 10734131 10753833 12803886 16283355 16418395 20510871
SPI1 GATA1 â—¼   PROTEIN_INTERACTION 6.0 1.0 ACSN 10734131 10753833 12803886 16283355 16418395 20510871
SP1 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12706891 22734486 10446912 7478579
SPI1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10823830 11481336 14962802 19801646
SPI1 GATA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14559995 10411939 11023493 11001896 20304827
SPI1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10523830 9858537 23056458
SPI1 CSF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12130514 12958595 10677505 20864248
SPI1 IL12B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11449355 25567680 11254706
SPI1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10801783 11359842 7799967 18173740 18566416 9376596 11823535 19423615 10328874 17283046 10453013 16439360 17386941 7609733 12061786 9360994 10490619
GATA1 SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10411939 10753833 15676205 10364157 12202480
THBS1 CD36 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 10657674 11982756 14568985 14996710 17101731 20150200015 21378271 22943793 8349738 9295024 9763615
THBS1 CD36 â—¼   PROTEIN_INTERACTION 11.0 1.0 ACSN 10657674 11982756 14568985 14996710 17101731 20150200015 21378271 22943793 8349738 9295024 9763615
THBS1 SDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11257118 1969657
THBS1 CD36 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10487979 10772961 1379600 23640500
HIF1A EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 16189267 20404921 15838297 21212189 8089148 21054399 10559391 11001829 8756616 20043814 8660378 16684536 16281953 8260699 10207038 8900415 11914036 10477681 11707426 9235919 10202154 11812905 18423195 21309574 15347669 15315937 11971899 14741200 9236155 7836384 7852211 17712557 9654078 24023421 10837481 20631191 8663540 10415537
HIF1A FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19492421 16399861 17536272 17942638
HIF1A EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19783678 11352889 18411415 17431122 12023962 11278891
HIF1A EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20513003 18174278 16924414 19030186
HIF1A MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16099863 17028975
HIF1A IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20865400 17548584 19490965 22964004 24352507 25750431 16504308
HIF1A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19144925 17220299 17488804 14726529 15277220
HIF1A TLR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19828020 18159247
HIF1A TGFB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7539918 8943284 1823643 12829734 9159130 10712429 13130303 11566883 12080085 10403805 9746763 15451019 11790723 9278421 16887934
HIF1A EDN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7539918 1823643 16716598 12829734 9159130 13130303 9588211 12080085 11566883 10403805 9746763 8943284 15451019 9278421 16887934
TLR2 CD36 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10549626 22028855 10426996 10364168 16880211 10490993 14977973 11123271 11431423 18178856
NR1I2 CD36 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16556603 18072748 19436068 18242221
ESR1 EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10894157 15075211 20889718 8770893 19423651
AR EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18511414 8580999 7522959 15590903 14662770 18692155 17374439 18212060 20610535
SP1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8864062 16928829 16704988 23662037 10773882 9353275 15661808 17984071 18430409 22347450 20739403 8994183
SP1 IL12B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16518544 20121399 15270850 19134014
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
SP1 CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17965828 9528783 20506344 17471507
SP1 APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22901716 11278817 10829013 15164326 15375792 11121483 23293065
SP1 PRKCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19145069 11327698 12105191 11578973 12727210 17257588 15533438 18295514 11336542 9756852 17509747 20092859 12694408 19464346 11060301 15380450
SP1 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11910354 12473536 9223667 15067326 21831840 17283128
FGF2 SDC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20382221 8621465 16982797 1101561416982790 8609172 11015614
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
AR AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20589722 11278645 17896924 18687691 22740037 12621049 12063252 22970326
STAT5A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24218138 24469394 18042802 20385773
AKT1 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27053161 16107690 20101202 8206977 26680303
AKT1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27997540 24291004
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17470458 18349820 29861848 16210317 21601007 17570479 11404460 22155408 12621049 14555644 11156376
AKT1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
PRKCA PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9015864 11278470 9349568 2211670 9307019 17570479 21338571
PRKCA MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 17496910 11940581 21386996 15075332 11447289 19615955 8294430 16488589 6321473 8321321 12845332 11313945 17570479 94124523 12040186 19568798 15567848 14585353
PRKCA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 92316961 15212693 26888287 1377674
PRKCA GFAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 9099667 7822264 12177195 2155236 2114109 12686604
PRKCA SDC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9244383 19901323
PRKCA PLCB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11278298 9660757 15302935 10893237
NR3C1 CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10649448 1840554
CEBPD HP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14661730 11027530 15694370 11559710 17910034
CTCF CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19129223 22422629
HSPA8 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21148293 10666020 19878303 21697503
GNAQ PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11753430 1309799 12193606 16754659 8245028 8387502 1322796 1846707
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
STAT5A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11731618 22201800 11682624 11682625
ESR1 APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11013347 18005483 9535920 17532863 23293065
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
KMT2D ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 16603732
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
AR VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12020745 20610535 14684616 18451309
NR3C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
AR NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
USF2 USF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14669984 12857727 11075816 19416648
USF1 TGFB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11776974 10567368 8943301
USF1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16943425 12000849 17970752 19704006 19491096
GTF2I USF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21282467 9384587 1961251
MYB NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16263717 15044598 22516378
NR2F2 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 14739255 15265774
NR3C1 NR2F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 14739255 15265774
GATA1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 18586828 22164220 12556498 15358512 20564185 12556492 1559609 3243278 15833715 12379744 14695898 21220744 2461328 2911469 12193659 17196618
POU2F1 VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12144930 9694713 17192276
POU2F1 H2BC11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 3677172 2123291 16827100 2532066 8227066 1887216 1416992
UPF2 UPF3B â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
HP APOA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15533931 19758344 17824618
FLI1 GATA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8510925 20110178 21205096 12724402
FLI1 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12556498 12724402 16189514 10364157
EPAS1 EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16281953 17712557 9113979 18056838 9000051 16971531 17804822
PRKCB MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PRKCB SDC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9244383 19901323 17570479
GATA1 EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16471262 8677751 8288642
IL12A IL12B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 10779781 10899108 8943050 7527811
HMGA1 SELE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7520524 7523851 9016563 10090829
PRKCG MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
USF2 TGFB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11776974 10567368 8943301