TFDP1
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14618416
|
E2F6
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12771133
18319725
|
E2F1
|
TK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11799067
|
E2F1
|
E2F6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16107498
|
MYC
|
PRPS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18677108
|
MYC
|
EZH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21941025
19197161
|
MYC
|
ST3GAL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22547830
|
MYC
|
ASS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19934275
|
E2F6
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
12004135
|
MYC
|
TFDP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11139609
|
SP1
|
YY1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22553354
|
YY1
|
PISD
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22951020
|
ATP5PD
|
ATP5F1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SP1
|
HPGDS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15790310
8557630
|
PRKD1
|
CDH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15695390
|
SP1
|
PDE6A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9770645
|
SP1
|
CERS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22169644
|
SP1
|
CYP2B6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20371701
8751713
|
SP1
|
ADH5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9867805
12004059
|
SP1
|
APRT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11870072
10976926
|
SP1
|
LDHC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18930904
|
ATP5PD
|
HADHA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PIGF
|
PIGG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15632136
|
ATP6V0A2
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
809.0
|
0.81
|
STRING
|
36370105
|
MYC
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
CDK2
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
21319273
|
MYC
|
IDH3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
LRRK2
|
LDHA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
24725412
|
LDHA
|
LDHC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CYC1
|
NDUFB8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
CDC20
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
MYC
|
DPM1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21150319
17314511
29467282
|
MAX
|
E2F6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
27705803
33961781
25609649
24981860
29028833
|
E2F6
|
EZH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16565076
15536069
|
ATP6AP1
|
ATP6V0A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
MYC
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
CDK1
|
CDC20
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
10799291
26912231
|
CDK2
|
TFDP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
33961781
9199321
25852190
|
CYC1
|
NDUFA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
COX5B
|
NDUFA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
848.0
|
0.84
|
STRING
|
36370105
|
MAX
|
TFDP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
27705803
33961781
25609649
24981860
29028833
|
CDC20
|
FZR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
LRRK2
|
DVL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
31046837
19625296
|
ATP6V0A2
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
PDE6G
|
PDE6A
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
-
|
0.86
|
0.86
|
Signor
|
20940301
|
CDK2
|
CDC20
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
26811472
33961781
25852190
23455922
|
PIGS
|
PIGT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
11483512
26496610
33961781
22939629
12802054
|
TFDP2
|
E2F6
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
8153045
21516116
|
SP1
|
YY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
CDK1
|
EZH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
E2F1
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
8458319
7969176
9199321
1530885
11245432
|
MYC
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16713569
11274368
18003922
17418410
15780936
32115405
|
CDK2
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11598016
19450264
|
CDK2
|
TFDP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12006580
11420722
9315635
|
PDHB
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
PKM
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
ATP5F1B
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CSAD
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CDKN1A
|
TFDP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11884610
7797074
9144196
|
CDKN1A
|
TFDP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11884610
7797074
9144196
|
TFDP1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10029406
10702805
9191053
|
E2F1
|
ALG5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12629508
|
SP1
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10547281
8657141
10850422
|
E2F1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11564866
18319725
90001421
|
MAD2L2
|
FZR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17719540
11459826
|
YY1
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
18490439
19219071
2191300
|
MYC
|
PLA2G4A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
AMPD3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
COX7A2L
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
ALG5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
GALT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
FUT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
ACYP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
IMPA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
ALDH9A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
PIGF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
HSD11B2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11274368
16713569
|
YY1
|
NOS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19402223
20430007
|
HMOX2
|
ATP5F1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
ATP5F1B
|
TK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
GCLC
|
GCLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
26653790
26794443
27048822
|
GCLC
|
GCLM
|
â—¼ PROTEIN_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
26653790
26794443
27048822
|
SP1
|
GCLC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15342415
23133636
18245173
|
SP1
|
LDHA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7998973
9723176
|
EZH2
|
TK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
E2F6
|
TFDP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
32296183
16189514
25416956
9501179
20211142
9704927
27705803
33961781
24981860
26186194
26871637
15536069
|
E2F6
|
TFDP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
32296183
16189514
25416956
9501179
9704927
27705803
9689056
33961781
24981860
26186194
21516116
26871637
|
PKM
|
TK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CDK1
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
CDC20
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
CDK2
|
FZR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
PIGS
|
PIGT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
E2F6
|
TFDP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
COX5B
|
CYC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
CYP51A1
|
HSD17B7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
PDE6B
|
PDE6G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
PDE6A
|
PDE6G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
TFDP1
|
E2F1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
24981860
|
TFDP1
|
E2F6
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
24981860
|
CDK2
|
CDKN1A
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.95
|
0.95
|
Signor
|
15964852
|
E2F1
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10850422
10409740
8657141
10547281
8657142
|
TFDP2
|
E2F1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
7739537
9501179
9704927
35140242
9368098
8755520
26186194
33961781
|
E2F1
|
TFDP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31130363
25368385
20211142
28542143
35140242
9780002
8816798
8657117
9199321
19015639
8816502
16360038
15133492
8405995
30867845
8832394
7892279
7739537
9501179
9704927
27705803
22629304
24981860
9464260
|
CDKN1A
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16765349
5218735
|
ATP6V1E1
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ATP6V1E1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ATP6V1F
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
E2F1
|
TFDP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
CDK2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
MAX
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CDK1
|
CDC20
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12124778
14551205
14614141
15242590
15279786
15375219
15377654
15485915
15917306
16713580
16818604
17303408
17596790
17660363
18414028
18543256
18590585
18995830
19652693
19686080
7575488
9892021
|
CDK1
|
E2F1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
14551205
15279786
17218262
17303408
17660363
18414028
18590585
7575488
|
MYC
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18802399
2237430
8065306
11085504
|
E2F1
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15510213
7623816
14618416
12760745
11799067
8137237
12629169
17108174
|
CDKN1A
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
9467962
26186194
21308745
15340381
23602568
23543736
24218572
17679094
15077146
26496610
12973835
|
CDK1
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
25398907
28831131
20150555
22266860
|
CDK1
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
8087847
27175585
17570479
17660363
15279786
|
CDK1
|
EZH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
28.0
|
1.0
|
Omnipath
|
25841987
34381492
25691891
27941792
27653691
23549878
25800736
22187039
23241245
25038756
25334066
22964433
27716745
20935635
21131960
29576612
33593912
21123648
23438432
21659531
26552009
|
CDK1
|
TK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
20068231
9575153
19413330
12435275
14697231
|
MYC
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
19887899
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
24954210
25002027
28536364
7575488
9618481
|
MYC
|
CDK2
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
19887899
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
24954210
25002027
28536364
7575488
9618481
|
CDK2
|
FZR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
10323868
10375532
16582612
12730199
|
CDK2
|
E2F1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
12086603
14536078
14988723
15136767
15147722
15175241
15279786
15798197
16713580
16805667
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18469862
18590585
18636226
18995830
19282663
19342888
19622404
19793801
20051983
7575488
|
CDK2
|
TK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
25003822
12435275
14697231
9575153
|
CDK2
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
8386367
27653698
17081983
19966300
18669648
29896817
17570479
20713526
17558397
15103331
22348395
20445224
|
CDK2
|
EZH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
20935635
25800736
29576612
23241245
32368395
29556394
17570479
27863310
26279746
|
CDK2
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
7575488
18590585
9315635
17303408
17570479
25101673
16213134
17660363
12006580
11420722
15279786
|
CDK2
|
FZR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
11598127
15577895
9736735
12560341
15558010
20068231
10548110
16123593
15840442
18669648
|
CDK2
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
94.0
|
1.0
|
Omnipath
|
23443559
23455922
10878006
20100570
23602568
15964852
20839231
25416956
23737759
9840943
18850315
11302688
20519948
24358021
19440234
15557281
9472014
9658399
16962592
9736735
12949733
8641969
10022118
15890360
12839982
16765349
17418410
15647383
10874474
15232106
17570479
17698606
12361598
26496610
9632134
24419005
12417722
16189514
26186194
20587660
25241761
8622677
9660939
25483090
12800980
20102411
10918595
12058028
12144826
8242751
9464540
9858587
29899857
23007395
11477082
9218599
12383116
25463440
12730199
8756624
9284049
9380407
9546435
24218572
16964243
15212693
13678583
|
EZH2
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
21572997
21546904
24074410
21629038
22956625
|
MYC
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
15190211
14519204
15616584
12408868
19174556
21949397
10319992
12553001
16204065
12545156
20878079
21042278
21400515
20190815
16706751
23804320
15757889
10920185
19270520
16452181
12408820
15528212
22371483
12565816
17885207
12384701
11274368
19150257
20551174
15899785
21120446
15071503
15474507
22814619
12835716
12748190
16738884
15711923
18636159
|
E2F1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9748148
9191053
16923815
17008321
10030670
10702805
15048076
17167174
|
SP1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
101.0
|
1.0
|
Omnipath
|
9580699
15978937
15557281
11064455
16103879
19584258
20301197
20935676
15961274
15361832
11274368
11842244
15489892
15302882
10212208
12796485
23184467
14529564
12806965
9819384
10321829
10649433
12434298
18270969
18850004
16081043
9183012
21858218
10809237
9618481
16298343
11574165
10362258
11384995
15659839
14744793
10030670
17090534
10733944
19318349
12665570
18202149
17516505
15033443
22001409
17885207
10485470
9553133
15345676
15694838
22427654
17556661
10506225
23066038
15979845
18636159
14527674
24821727
15899840
14755691
12151347
24589735
18210215
23877711
11953011
21311948
15528212
15790310
10878024
22132221
12782287
12773551
8995437
21184768
12379120
17026958
24451377
10601254
8557703
16810128
16533812
7499379
10625687
15389873
16706751
12727210
21325288
16818630
18419600
15041706
23235480
19244234
15694666
23329847
18509005
|
MYC
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
15528212
9618481
12545156
17550342
10454538
15155580
11283613
10920185
11283614
|
SP1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17026958
9389648
9618481
17550342
12545156
11013220
15155580
11074002
|
CDKN1A
|
TFDP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
9190208
10498883
9315635
10385618
10778858
9736735
7736585
9425340
11520855
|
CDKN1A
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
9190208
10498883
18590585
7575488
9315635
17303408
10385618
10778858
9736735
16236519
20068082
7736585
9425340
11520855
19075565
18786381
17660363
15279786
|
E2F1
|
CDC20
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
15279786
17218262
17303408
17660363
18590585
7575488
|
SP1
|
E2F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9054613
12697671
10446910
18440323
|
E2F1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
8208548
2721961
7753559
11705881
24038073
8355712
1549358
1567856
12629508
|
TFDP2
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
26186194
9704927
9368098
8755520
9501179
7739537
|
E2F6
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18562691
18319725
9689056
12004135
12909625
|
E2F1
|
TFDP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
20211142
15133492
22327218
7892279
16360038
9199321
8405995
9704927
8816798
9780002
8657117
9464260
22629304
7739537
27705803
25368385
9501179
8816502
8832394
|
E2F1
|
EZH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18319725
14532106
|
MAD2L2
|
CDH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20074045
11459826
|
MAD2L2
|
CDC20
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
17719540
20074045
11459826
|
MYC
|
MAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11274345
12040186
15121849
16908182
2006410
8425218
|
MYC
|
MAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
16596619
21988832
10229200
17471507
26267534
15572685
18003922
20382893
35140242
17418410
25609649
16352593
31767764
17072308
17289033
10918583
9528857
14749374
21807113
19623651
18620061
25522242
32296183
16140957
16705173
19578763
26496610
12584560
17157259
17643117
24951594
20946988
10465786
12706874
12821782
9184233
17353931
10611234
32140074
8266081
20691906
16410719
21150319
10593926
12660246
27859590
12553908
8224841
10319872
2006410
16287840
16606833
23816886
9708738
17314511
9886493
27705803
33298911
33961781
20936779
12824180
9680483
17700062
29467282
30415952
12391307
|
MYC
|
LDHA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
11274345
11283613
11283614
11704864
15199147
16782875
17055429
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
25002027
28536364
8955077
9192621
|
MYC
|
MAX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11274345
12040186
15121849
16908182
2006410
8425218
|
YY1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
9797456
16314465
10528225
8266081
19279113
17287852
10713181
18490439
17434929
16878156
18542060
|
SP1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11470523
9492315
2284094
8437848
7753559
8355712
2057364
|
MYC
|
LDHA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16319523
9723176
11085504
14519204
11983916
9192621
|
MYC
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9632747
19176757
23364919
10523846
|
MYC
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
14519204
11896591
8376401
10421838
|
MYC
|
SHMT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12138190
18628958
|
MYC
|
MAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10508165
15665468
8385351
8649388
8521822
22384171
1406956
17341548
|
YY1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8266081
15805285
18490439
19219071
2191300
|
MAX
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
90.0
|
1.0
|
Omnipath
|
17145710
16287840
25609649
12821782
16606833
16596619
21807113
25522242
20691906
19578763
24951594
8224841
17643117
9528857
12391307
16705173
21150319
10229200
21988832
15572685
9680483
2006410
17314511
14749374
12553908
17289033
17418410
19623651
12824180
17157259
12584560
26496610
20946988
20936779
8425218
23816886
17353931
10319872
17471507
18003922
16140957
20382893
12660246
8266081
7565735
32296183
10465786
26267534
17072308
27705803
9184233
18620061
10918583
17700062
10593926
10611234
16352593
9708738
|
MYC
|
LDHA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16782875
17093053
15199147
8955077
9192621
|
NDUFA4
|
NDUFA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA4
|
NDUFB8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA4
|
NDUFB8
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA4
|
NDUFA6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA6
|
NDUFB8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA6
|
NDUFB8
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
GLUL
|
PYGL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
GLUL
|
PYGL
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
GLUL
|
PYGL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
EZH2
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
18377425
22130667
21685935
21770894
|
EZH2
|
CDH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
15169839
17615296
22796940
20818389
21685935
20519943
12508111
11309385
17018611
22514743
19597490
20574448
14673164
|
DVL2
|
LRRK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
20006983
19625296
|
SP1
|
CYP11A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10459866
10383457
20371701
9013760
12217897
10446912
|
SP1
|
MAOB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15279563
19401466
14697878
20980443
11956220
11259630
15024015
12855685
|
SP1
|
PNMT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
14573768
10085109
16926281
19539715
21046459
19220706
7615530
12694408
20654592
|
SP1
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
15908479
16341057
9671487
1845987
8803927
2542772
7565693
15608673
9566920
1404598
2170405
10421838
|
EZH2
|
ME3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
22179855
22312437
23788032
24018208
21512140
24737471
23932971
20368440
24928441
19053175
23424038
24032713
20634887
18704159
24652950
22072987
|
PDE6G
|
PDE6B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
9459445
16908407
6286681
10564809
19818506
12119397
14702087
10051575
10676965
|
PDE6A
|
PDE6B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
9459445
16908407
6286681
10564809
19818506
12119397
14702087
10051575
10676965
|