FOXO1
|
CASP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19050291
20200974
|
H2AC14
|
CTPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
FOXO1
|
IDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25648147
|
JUN
|
HPGDS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8617242
8206948
|
JUN
|
CPS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
|
JUN
|
HDC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9341140
9142914
|
JUN
|
CYP3A4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14742674
|
DLD
|
BCKDHB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
2188967
10745006
|
COX4I1
|
KLF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
EGR1
|
CDK5R1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15289351
|
EGR1
|
AKR1B1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12890669
|
GAPDH
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
CDK5
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
H2AC21
|
ENO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
APP
|
GAPDH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
GAPDH
|
H2AC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
GNAQ
|
GNB4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25675501
15889144
|
APP
|
KLF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
GYS1
|
GBE1
|
â—¼ GLYCOSYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8613547
22248338
|
GYG2
|
GBE1
|
â—¼ GLYCOSYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15452297
8613547
|
MAOB
|
KLF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
MAOB
|
MAOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H2BC15
|
H2AC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
JUN
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17056544
25609649
|
DGUOK
|
GNAQ
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
GRIA3
|
GRIA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
AOC3
|
EXTL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ATP6V0B
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
PAX3
|
DAXX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11244500
10393185
|
DGUOK
|
DCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DGUOK
|
ATP4A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
COX4I1
|
COX6A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
IDH1
|
IDH3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
845.0
|
0.84
|
STRING
|
36370105
|
IDH1
|
IDH3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
845.0
|
0.84
|
STRING
|
36370105
|
DAXX
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
845.0
|
0.84
|
STRING
|
36370105
|
NDRG1
|
LDHA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17220478
22863883
|
KLF11
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
11438660
16713569
|
IDH2
|
IDH3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
ARRB2
|
DRD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
32450252
21256133
25162404
|
IDH2
|
IDH3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
COX4I1
|
COX6A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
GSTA2
|
GSTA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
25416956
25910212
33961781
26186194
|
GSTA2
|
GSTA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
IDH3B
|
IDH3G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
16189514
16713569
31536960
10677231
33961781
26186194
|
FOXO1
|
GCK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18805788
16492665
19740748
|
CDK5
|
DRD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
24391960
|
GOT2
|
GAPDH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
APP
|
GAPDH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
21832049
16713569
8473906
|
GYG2
|
GYS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1B2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V1B2
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
CDK5R1
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
23543736
|
ATP6V1C2
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
ATP6V0B
|
ATP6V0C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
ATP6V0B
|
ATP6V1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
COQ6
|
COQ3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
27499296
26344197
|
ATP6V0C
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1B2
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
CDK5
|
CDK5R1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.94
|
0.94
|
Signor
|
18326489
|
ATP6V1B2
|
ATP6V1C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
ATP6V1C1
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
DLAT
|
DLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
IDH3B
|
IDH3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
DAXX
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
24550390
12529400
10669754
29084956
32545337
|
ARNTL
|
NPAS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
ATP6V1E1
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1B2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
ATP6V1B2
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
APBB1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
GNB4
|
GNG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CDK5
|
CDK5R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
JUN
|
HMOX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8774698
24755082
8872603
20486760
20833713
18689604
|
JUN
|
APP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8063812
11677255
8015372
|
CDK5
|
CDK5R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
11583627
23602568
15689152
11389014
17036052
25076872
21220307
15890360
16189514
23979715
26186194
17591690
17762160
14521924
20133653
22654103
28637746
12223541
23543736
18326489
28077789
17121855
|
CDK5
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
18833287
15178331
15917097
11877420
17085446
16554819
21947912
8131745
11517218
17459339
14970211
10341243
16705182
24610780
22112898
8764598
14557249
16223726
19455415
19090995
10936190
11146006
15944381
|
CDK5
|
GRIN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
27443506
22870316
20685978
11675505
28045138
22836916
|
KLF11
|
MAOB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22890201
15024015
|