H4C6
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16628214
5218530
|
FBXW7
|
MMS22L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SSRP1
|
MCM7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218941
16902406
|
H2AX
|
RAD51
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8149296
21317870
|
SUPT16H
|
MCM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218941
16902406
|
H2AX
|
H4C6
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
24981860
|
MCM6
|
MCM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
ASF1A
|
MCM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HuRI
|
32296183
|
MCM2
|
SSRP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
TONSL
|
MCM4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21055985
21113133
|
H2AX
|
MCM4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ASF1A
|
MCM6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
22407294
|
ASF1A
|
MCM7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
22407294
|
ASF1A
|
MCM4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
22407294
|
BRCA1
|
TONSL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25184681
29656893
|
ASF1B
|
MCM7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
26527279
33961781
28514442
|
H2AX
|
TONSL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
28242625
|
TONSL
|
MCM6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21055984
21055985
21113133
|
TONSL
|
MCM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21055984
33961781
21055985
21113133
|
MCM2
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
25963833
|
H2AX
|
MCM6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
28242625
|
ASF1B
|
MCM4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
26527279
33961781
28514442
|
ASF1B
|
MCM6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
20227376
33961781
26527279
21055984
|
MMS22L
|
TONSL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
ASF1B
|
TONSL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
SUPT16H
|
SSRP1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
5218941
16902406
|
ASF1B
|
MCM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
20227376
26167883
25963833
33961781
24981860
26527279
|
MCM2
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
856.0
|
0.85
|
STRING
|
36370105
|
SSRP1
|
MCM7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
21055985
16902406
|
H2AX
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31009828
30560944
21317870
28796254
29499138
28190324
10959836
|
SSRP1
|
MCM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
16902406
21055985
33961781
24981860
|
SSRP1
|
MCM6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
21055985
16902406
|
ASF1A
|
H4C6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
ASF1A
|
ASF1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
H3C2
|
ASF1A
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
7219095
19498464
|
ASF1A
|
H3C2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
24981860
|
H3C2
|
ASF1A
|
â—¼ PROXIMITY
|
✅
|
|
0.88
|
0.88
|
mint
|
25281560
|
BRCA1
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
MCM4
|
SSRP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
TONSL
|
SSRP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
21113133
25184681
21055985
33961781
|
TONSL
|
ASF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
21113133
22407294
33961781
34079125
21055984
|
SSRP1
|
MCM4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
21055985
33961781
16902406
|
ASF1B
|
TONSL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
21113133
17353931
33961781
21055984
|
H3C2
|
H4C6
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
7219095
19498464
|
ASF1A
|
MCM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
32296183
26167883
25963833
22407294
23602572
33961781
24981860
|
H2AX
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12485996
34321665
19766185
18001824
31501894
11927591
18344987
20681793
26095369
18001825
29499138
19805520
26121674
10959836
12419185
|
RAD51
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31270457
31009828
11498787
16713569
19766185
25659039
19369211
25499220
9774970
28319063
17302439
9008167
14636569
28976962
24085845
34408138
29656893
|
BRCA1
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16713569
9774970
9008167
|
H3C2
|
ASF1B
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
7219095
19498464
|
ASF1B
|
H3C2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
24981860
|
H3C2
|
ASF1B
|
â—¼ PROXIMITY
|
✅
|
|
0.9
|
0.9
|
mint
|
25281560
|
ASF1B
|
H4C6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11985607
12842904
|
H2AX
|
SSRP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
28514442
33961781
24981860
18406329
16522924
|
MCM2
|
TONSL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
RAD51
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.95
|
STRING
|
36370105
|
ASF1B
|
ASF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
12842904
22407294
26496610
24981860
34079125
|
MCM4
|
MCM7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12364596
12694531
20808282
8631321
8798650
12207017
9099751
12614612
7601140
10748114
23764002
24299456
15232106
22939629
17296731
10567526
22540012
22863883
27173435
26344197
|
ASF1B
|
MCM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
MCM7
|
MCM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16189514
12694531
20808282
8798650
12207017
14681455
9099751
12614612
10748114
23764002
15232106
25963833
30100344
22939629
17296731
10567526
22540012
22863883
33961781
27173435
26186194
16899510
26344197
|
MCM7
|
MCM6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
22939629
12694531
12614612
20808282
16438930
26496610
12207017
23764002
27173435
17296731
9099751
26344197
|
MCM2
|
MCM7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
MCM6
|
MCM7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
MCM4
|
MCM7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
MCM2
|
MCM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
SSRP1
|
SUPT16H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ASF1A
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15664198
10759893
11985607
|
ASF1A
|
H4C6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11985607
15664198
25416956
32296183
10759893
|
BRCA1
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
RAD51
|
â—¼ SHARES_COMPLEX
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
H2AX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18001824
18001825
17145710
12419185
|
RPA1
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17720710
12226657
18342608
20129063
|
RPA1
|
MCM7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
MCM7
|
MCM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
MCM7
|
MCM6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
MCM7
|
MCM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
RPA1
|
MCM7
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
MCM7
|
MCM2
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
MCM7
|
MCM6
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
MCM7
|
MCM4
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
RPA1
|
MCM7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA1
|
MCM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA1
|
MCM6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA1
|
MCM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA1
|
MCM6
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA1
|
MCM4
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA1
|
MCM2
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA1
|
MCM4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA1
|
MCM2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA1
|
MCM6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
MCM4
|
MCM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
MCM2
|
MCM6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
MCM4
|
MCM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
16902406
12694531
22939629
12614612
25963833
10567526
22540012
8798650
14681455
22863883
33961781
27173435
16899510
17296731
26344197
|
MCM6
|
MCM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
16189514
25416956
12694531
20211142
14681455
12207017
12614612
26496610
25963833
30100344
22939629
17296731
26167883
10567526
22540012
22863883
33961781
27173435
16899510
26344197
|
MCM4
|
MCM2
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
MCM2
|
MCM6
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
MCM4
|
MCM6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
MCM4
|
MCM6
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
16902406
12694531
12364596
12614612
22939629
26496610
8798650
12207017
22863883
27173435
17296731
26344197
|
MCM4
|
MCM6
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
ASF1B
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11985607
17353931
15664198
27753532
12842904
|