Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CYCS APAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9267021 5221616
APAF1 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 5214497 11550094
BAX APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11709054
MAPK9 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14673001 17555943
BAD CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15725726
HSPD1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18266962
MAPK1 BCL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217079 15225643
CEBPG BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16254192 12970736
MAPK1 BCL2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5217079 15225643
BCL2 MAPK8 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15733859 5217553
BCL2 CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16713569 10622714
CASP3 BID â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CTSL BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14581476
FADD BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15659383 25241761
CTSS BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14581476
BID CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9873064 9727491
CASP8 CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18669646 0712034105
CASP9 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
AKT3 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
CASP3 AKT1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
CASP3 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 12011067 15573119
CASP3 AKT2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
CASP3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9500443
HLA-DRA CD74 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218024 16242130
CD74 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218024 16242130
CD74 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218024 16242130
HLA-DMB CD74 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2391366 8574855
HLA-DMA CD74 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2391366 8574855
CEBPG ITGAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9250811 9360988
DYNC1I1 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
MAPK11 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DYNC1LI2 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
NDEL1 DYNC1H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11163259
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
EP300 RELA â—¼   ACETYLATION ✅ 2.0 0.8 intact 5214468 11533489
MAPK3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24530506
EP300 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21988832 20089040
HSPD1 MRC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPD1 FADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
IL1A IRAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8599092 9430229
IL1A IRAK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12538665 17507369
SRC MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
RAF1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 20674547 15664191
MAPK1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
MAPK1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8941362
MAPK1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15778365
PPM1D MAPK12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15870257
SYK MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12038794 8636072
MAPK11 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23602568 21900206
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK3 CASP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219611 17290218
RAF1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 20674547 15664191
MAPK3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
MAPK3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16888388 16691505
TLR4 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17047224 17823124
CD14 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17047224 17823124
HSPA9 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CALR TAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22153078 25083866
IL10RA IL10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11485736 5214351
CREB1 IL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
IL10 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12773629
SYK CLEC4E â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17050534 18776906
SRC ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 7296071 19903481
NFYC NFYB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215853 12401788
NFYB CIITA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10913187 12697811
CALM3 CAMK2D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20668654
CALM3 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9813038 8918462
CALM1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
CALM1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9813038 8918462
CALM1 CAMK2D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20668654
ACTG1 RIPK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CALM2 CAMK2D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20668654
CALM2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9813038 8918462
SRC ITGB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19910644 10592173
ITGB5 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19910644 10592173
CREB1 CYCS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18227154 16908542
ATP6V1G1 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ITGB3 ITGAV â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214491 11546839
HLA-E SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9830044 9396765
SYK MAPK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12038794 8636072
JAK1 IL12A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22306691 12829785
JAK1 CAMK2D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
JAK1 CAMK2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
JAK1 CAMK2G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
JAK1 CAMK2A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
IFNGR2 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15120645 23331499
IFNB1 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10918594
IL10RB JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 12974481
IL1B IRAK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12538665 17507369
IFNGR1 IFNG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 376230 7617032
IFNGR1 CAMK2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
IFNGR1 CAMK2A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
IFNGR1 CAMK2G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
IFNGR1 CAMK2D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
IFNG CAMK2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
IFNG CAMK2D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
IFNG CAMK2G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
IFNG CAMK2A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
JAK2 IL12A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22306691 12829785
JAK2 CAMK2A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
JAK2 CAMK2G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
JAK2 CAMK2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
JAK2 CAMK2D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
SRC JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 17158356
CREB1 IL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
NCF4 CYBA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5223350 17803994
RAC1 CYBA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10486263
CASP8 RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAF1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19197339 7014125
RAF1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30761125 27554335
IL1B CASP8 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 1574116 22267217
RELA RIPK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19693652
RELA BRMS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21765477 19165610
RELA HLA-DRB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18421578 15964798
CD14 CD36 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16880211 18178856
CREB1 HLA-E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
TLR4 CD36 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20037584 7685021
THBS3 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HLA-DRB3 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAC2 NCF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213243 11090627
NCF4 NCF2 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 5214329 11483497
CREBBP IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
CREBBP VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10406465
TLR2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11101877
SRC FCGR2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC FCGR2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PTPN1 SRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6732073 9600099
SRC FCGR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8756631 18083107
IFNGR2 CAMK2D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
IFNGR2 CAMK2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
IFNGR2 CAMK2G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
IFNGR2 CAMK2A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
CAMK2A AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR2 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16549430 17261755
MAPK8 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16306447
ITGB3 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16005629 16115959
COMP ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20033473 32196115
ITGB3 PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16115959
CREB1 HLA-DQB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1324879
CREB1 HLA-DOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12938212
MAPK11 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11532940 11335727
CEBPB CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12773552
CEBPB CYP27B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19261615 20560977
CEBPB MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9743233 22139077
CEBPB LBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9442384
HLA-DRA HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CANX HSPA9 â—¼   COLOCALIZATION 2.0 0.8 intact 8372609 22045338
PTPN1 RHOB â—¼   COLOCALIZATION 2.0 0.8 intact 14722096 6672086
AKT2 PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11579209
CIITA HLA-DMA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7495736 9300700
ATP6V1G2 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14667819 5216829
DYNC1I1 DYNC1LI2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
DYNC1LI2 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
DYNC1LI2 DYNC1I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
CAMK2D CAMK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20668654 1000426
LGALS3 CLEC7A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1237910 24072822
LGALS3 FCGR2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1237910 24072822
CARD9 RIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17187069 17486093
HLA-DQB1 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11376336 5214072
HLA-DQA2 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQB1 HLA-DQA1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
HLA-DQA2 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
IL23A IL12B â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
RFXAP HLA-DRB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18723135 11258423
RFXAP HLA-DQB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18723135 11258423
ACTB DYNC1I2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
MAPK8 MAPK9 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
ATP6V0D1 ATP6V1B2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
ATP6V1B1 ATP6V1H â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
ATP6V0A2 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
ATP6V0A2 ATP6V1B1 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
ITGA2 ITGB1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
ACTB DYNC1H1 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
ITGA5 ITGB3 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
BAD BAX â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19427863 17274640
ACTB EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33742100 21988832
CTBP1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21102443 15834423 35016035 16122695
LAMP2 XRCC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MBL2 CR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23460739 29563915
LAMP2 JAK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IRAK4 TLR4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21829704 21220427
PTPN1 JAK2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 6732089 11970898
PTPN1 JAK2 â—¼   DEPHOSPHORYLATION ✅ 0.82 0.82 mint 6673264 15821101
JAK2 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 0.82 0.82 mint 8287447 201095 21806020
RHOB SRC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
AKT3 AKT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ATP6V0A1 ATP6V0E1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
EEA1 RAB5B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12493736 10491193
IFNA4 IFNA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IFNA4 IFNA8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IFNA4 IFNA7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BAD BCL2 â—¼   RELOCALIZATION ✅ - 0.82 0.82 Signor 15694340
ATP6V1B1 TCIRG1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
ATP6V0B ATP6V1H â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
AKT1 BAD â—¼   PHOSPHORYLATION ✅ - 0.82 0.82 Signor 9346240
IL10RA JAK1 â—¼   UP_REGULATES ✅ + 0.82 0.82 Signor 26260587
JAK1 IL10RA â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 10433356
HLA-DQA2 HLA-DQB1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATP6V1E1 TCIRG1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
ESR2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11500849 18765668
NFYB EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10075648 9799238 15454570
IFNA5 IFNA6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TLR2 TIRAP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17258210 18221795
MRC2 NDEL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
IFNA2 IFNA5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
IFNA5 IFNA4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
AKT1 MAPK14 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
ATP6AP1 ATP6V0A2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CD74 CTSL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
C3 ITGAM â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ATP6V0A1 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ATP6V0D1 ATP6V1A â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
ATP6V0D1 ATP6V1H â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
ESR2 ACTB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 21951318
TIRAP IRAK1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 21903422
HLA-DRB1 HLA-DRA â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5220278 7477400
CALM3 NOS1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CALM1 CAMK2D â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CALM1 NOS1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CALM2 NOS1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CALM1 CAMK2B â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
ATP6V0D1 TCIRG1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CALM1 CAMK2A â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
MAPK1 RAF1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ATP6V1D ATP6V1G2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ITGAV ITGB1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CASP9 CASP3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11242052 8900201 25241761 1067155 15941357 11230124 15507451 18723680 17437405
AKT2 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 12149249 9736715 12176337 11445557 33961781 14500673 11278835 11546794
APAF1 CYCS â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CEBPB EP300 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
ATP6V0A2 ATP6V0C â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
JAK2 PTPN1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ATP6V0D2 TCIRG1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
ATP6AP1 ATP6V0D1 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
CASP8 BCL2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16183855 11406564
MBL2 CALR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 18177377 8062452
TIRAP IRAK2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11544529 21903422
VDR SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20371703 15919723 12796488 12893883 15604093 16434701 21917910
ATP6V0A2 ATP6V1F â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
HSPA9 HSPD1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
ATP6AP1 ATP6V1C1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
CYCS CASP9 â—¼   PHYSICAL_INTERACTION ✅ + 0.86 0.86 Signor 9390557
BCL2 RAF1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
FCGR2A SYK â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
ATP6V1D TCIRG1 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CLEC4E FCER1G â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
ATP6V0D1 ATP6V1D â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
CASP8 BID â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9727492 15659383 9727491 12097160 11832478 12196516 11085743
CASP3 BID â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10364179 11399776 18723680
CASP8 CASP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15254227 11832478 18669646 11437602 8962078
CD74 HLA-DRA â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
AKT1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21901101 15224190 21775285 20333651 18182168 11116148
SRC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
IRAK4 TIRAP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18221795 21903422
JAK2 RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9689060 11134016 8876196 10205168
CASP3 CASP9 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ATP6V0A2 ATP6V0D2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
NCF2 RAC1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MAPK1 MAPK14 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ATP6V0D1 ATP6V1F â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CD9 ITGB1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TIRAP TLR4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PTPN1 SRC â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BAD RAF1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ATP6V0A1 ATP6V0D1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
IFNA14 IFNA6 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CAMK2D CAMK2G â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CEBPB CEBPG â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12177065 20102225
EP300 VDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32603375 15647825 20089040 21988832
IRAK4 IRAK2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20485341 21903422
TLR2 CD14 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18765807 10395652 16189514
SRC ESR2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12095943 12630920 15604093 11013076 11032808
IRAK2 IRAK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12138165 21903422 10383454
AKT1 RAF1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CASP10 CASP8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DYNC1H1 NDEL1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ATP6V1B1 ATP6V1B2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ATP6V0C ATP6V0D1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AKT1 BAD â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
DYNC1I1 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
DYNC1H1 DYNC1I1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CREB1 EP300 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
ATP6V1E2 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
LBP CD14 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 2402637 7583357 12417309
ATP6V0A1 ATP6V1D â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
IRAK1 IRAK4 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
ATP6V0A1 ATP6V1A â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CREBBP RELA â—¼   ACETYLATION ✅ + 0.89 0.89 Signor 16382138
CASP8 BID â—¼   CLEAVAGE ✅ + 0.89 0.89 Signor 9727492
MAPK3 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19777442 10597268 12566304
MAPK1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8929531 10597268 12566304
BAX BID â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 15574335 20956295 23374347 17289999
AKT3 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14766748 15642728 17525161
CTBP1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12676992 7834749 15613549
RAF1 BCL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8929532 8910675 12488548 9194558 15849194
ESR2 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19211725 18223478 20664923
CEBPB BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12970736 19717648 17043638
CASP10 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16186808 15772077
VDR CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18832097 18259074
HLA-DQA2 CD74 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
RELA CD74 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8164652
EP300 CEBPB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28428115 9343424 14630807 12471036
NCF2 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16778989 10400704 27558335
MAPK1 NCF4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16778989 10400704 27558335
MAPK1 RAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17202194 15657136 21419341
MAPK11 MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RELA MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CARD9 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14560001 15692051 17187069
NCF2 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16778989 10400704 27558335
MAPK3 RAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17202194 15657136 21419341
MAPK3 NCF4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16778989 10400704 27558335
MAPK3 SPHK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17311928
VDR IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20691220
NFYB ACTB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1762920
CALM3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9859994 2550447 19608982
CALM3 NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7685187 7493936 1722402
CALM1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9859994 2550447 19608982
CALM1 NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7685187 7493936 1722402
CALM1 CAMK2G â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10860555 20668654
CALM2 NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7685187 7493936 1722402
CALM2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9859994 2550447 19608982
ITGAV COMP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16051604 20033473 15345499
FCGR3A SYK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 7517665 8657103 15161916
JAK1 SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10825200
ITGB1 COMP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16051604 20033473 15345499
PLAU ITGB1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 18633355 22470492 27216177
PTPN1 ITGB1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 201095 21806020 8287447
AKT1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16256741 10896934
SRC ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 11723131 11259684
CARD9 BCL10 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25416956 11053425 28765954 22267217 33789983
MALT1 BCL10 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21157432 31774199 23690623 25748427 17948050 20551178 17189706 21513986 22658522 22267217 14695475 22528498 27070702 31961340 11262391 24130731 27071417 33329596 19444310 27113748 25548215 11090634 30279415 19279678 25569716 18806265 33961781 29953499 19118383 27777308
BCL10 AKT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16280327 24462114 24412244
IL6 JAK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8134389 8272873 9382798
IRAK4 IRAK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24735611 12860405 19166926 18221795 12538665 17785851 11960013 16024789 16951688 17276401 21903422
HLA-C IFNG â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11513144 21339333 9605119
JAK2 IL12B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18389480 7638186 7528775
AKT1 RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 25241761 28628118 10576742 19197339 19058874 28205554
SRC RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17097642 16189514 7517401 8876196 10205168
RELA IL18 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10227974 17399992 15963597
RELA PLAUR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12244126 19020743
TIRAP TLR4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11526399 17258210 11544529 18221795 20048342 21829704 21903422
IRAK1 TLR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9625770 17635639
RAC2 NCF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9624165 9642115 16189514 11090627
NCF4 NCF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16297854 11893732 9490029 10672014 11483497 16782902 11796733 12887891 9083043 12813044
RAC1 NCF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25301945 9642115 16189514 25416956 9255350 8036496 11896062 11090627 9624165 7738010
THBS1 TGFB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22943793 8349738 21900405
ITGA5 COMP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16051604 20033473 15345499
RAC1 MAPK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18426980 18423204
SRC FCGR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8756631 17474147
ITGB3 COMP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16051604 20033473 15345499
ESR2 CTSD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16219765 10037443
CEBPB IL12B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11509602 24012417 11279072
IRAK1 TLR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10395652
RHOB ARHGEF12 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
HLA-DRA CANX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DQA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DQA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA1 CANX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA2 CANX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DPA1 CANX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
CANX IL12A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22487722 18033300 9342359
ESR2 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15664452 17088408 17556531
HLA-DQA2 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA1 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA2 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
RFXAP CIITA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12618906 15781111 11258423
IL23A IL12B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29997244 12023369 11114383 18680750
IL12B IL12A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10899108 10779781 7527811
VDR CAMP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15985530 22841393
VDR CYP27B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15934135 17250953 21307571
HLA-DMA HLA-DRB1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
DYNC1I2 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BAX BID â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
BCL2 BID â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
BAD BCL2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ATP6V0B ATP6V1D â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
ATP6V0B ATP6V1F â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
HLA-DPA1 HLA-DPB1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
CALM3 CAMK2B â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CALM2 CAMK2B â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CALM2 CAMK2A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
ATP6V1C2 ATP6V1D â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
CALM3 CAMK2A â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
ATP6V1B1 ATP6V1C1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
EP300 RELA â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V0C â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0A1 ATP6V0C â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0C ATP6V1B2 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0C ATP6V1C1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V1D â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0A2 ATP6V1D â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V1A â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V1B2 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0A1 ATP6V1B2 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V0A1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0A1 ATP6V1F â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0A1 ATP6V1C1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V1F â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CREBBP RELA â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
ATP6V0C ATP6V1F â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
DYNC1H1 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ATP6V0C ATP6V0D2 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
ATP6V1C2 ATP6V1F â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
ATP6V1B2 ATP6V1H â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
ATP6V0C ATP6V1G2 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
ATP6V0A1 ATP6V1G2 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
IL10RA JAK1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ATP6V1C2 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ATP6V0A1 ATP6V1B1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ATP6V0B ATP6V0C â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
ATP6V1B1 ATP6V1E2 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
ATP6V1B1 ATP6V1C2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
ATP6V0C ATP6V1H â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ATP6V0C ATP6V1A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ATP6V1C2 ATP6V1E2 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
SEC61A2 SEC61B â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ATP6V0B ATP6V1A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
MALT1 BCL10 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 17948050 6177522
SRC PTPN1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6672195 16115959
SRC PTPN1 â—¼   PHOSPHORYLATION ✅ 0.94 0.94 mint 6732073 9600099
PTPN1 SRC â—¼   DEPHOSPHORYLATION ✅ 0.94 0.94 mint 6764906 16537444
SRC PTPN1 â—¼   DEPHOSPHORYLATION ✅ 0.94 0.94 mint 11007774 6671922
ATP6V1B1 ATP6V1G2 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
ATP6V1B2 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
ATP6V1C2 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
ATP6V0C ATP6V1D â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V0C ATP6V1E1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1C1 ATP6V1D â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1C2 ATP6V1G2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1B1 ATP6V1F â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1A ATP6V1G2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1B2 ATP6V1C1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1B2 ATP6V1G2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1C1 ATP6V1F â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CALM3 CAMK2D â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CALM2 CAMK2D â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ATP6V1A ATP6V1C1 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
ATP6V1A ATP6V1F â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
ATP6V1B1 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
HLA-DMA HLA-DRA â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
ATP6V1A ATP6V1B1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
IRAK2 IRAK4 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
ATP6V1E1 ATP6V1G2 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
IL12A IL12B â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
ATP6V1B2 ATP6V1C2 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
C3 CR1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
ATP6V1C1 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
CAMK2A CAMK2B â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CASP9 APAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5221774 9390557
AKT1 BAD â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 15998799 10358075 25241761 11500364 9381178 11994280 23085457 15722337 19667065 15784622
CREB1 EP300 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12665587 21268077 10506141 21212407 11313407 7870179 17476304 22787115 26944191 33846793
ATP6V1A ATP6V1G1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CAMK2B CAMK2D â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
HLA-DRA HLA-DRB5 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
HLA-DMB HLA-DRA â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
ATP6V1D ATP6V1G1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
NFYC NFYB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 21988832 26496610 35140242 33961781 20936779 9388234 12401788 26344197
CAMK2A CAMK2D â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
ATP6V1B1 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
ATP6V1B1 ATP6V1D â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ATP6V1A ATP6V1C2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
IL12B IL23A â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
ATP6V1E1 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ITGAX ITGB2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ATP6V1A ATP6V1H â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
HLA-DMA HLA-DMB â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DYNC1I2 DYNC1LI2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CASP8 FADD â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 5219431 17159907
ATP6V1E1 ATP6V1H â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ATP6V1E1 ATP6V1F â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
BAX BCL2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
DYNC1H1 DYNC1LI2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ATP6V1B2 ATP6V1F â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
DYNC1H1 DYNC1I2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ITGA5 ITGB1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ATP6V1F ATP6V1H â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ATP6V1D ATP6V1H â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CREB1 CREBBP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
ATP6V1A ATP6V1B2 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
ATP6V1B2 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
ATP6V1B2 ATP6V1D â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
ATP6V1D ATP6V1F â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
APAF1 CASP9 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
BAD BCL2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16697956 15694340 7834748 9388232 17446862 9463381 20603619 10611223 14681455 11483855 33961781 19168699 15990872 9305851 15849194
BAX BCL2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 21778226 18981409 15899854 32064756 10620799 21199865 17289999 9194558 8358790 21671007 16642033 21458670 22262057 9388232 10716992 20865015 14980220 9111042 24141421 17097560 15231068 9463381 33961781 17525735 29749471 23479509 26004684
BID BCL2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16697956 15694340 19074266 11583631 9727491 9463381 15520201 14681455 17289999 18835031 12624108
FADD CASP8 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 21785459 23142077 21988832 23972990 17290218 24098568 14681455 20103630 33469115 18485876 22274400 22864571 25043603 27560715 25939870 29795330 19524512 17159907 30561431 27552911 19176810 15659383 9343261 22179575 22173242 25911380 27321185 8681376 15280356 21737330 26437781 31046799 21458669 12702723 11717445 21737329 19060883 21525013 23429285 20448643 12107169 17047155 9228018 12887920 29497034 12911633 14612908 23955153 33961781 20829884 26972597 21620750
CASP10 FADD â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
HLA-DRA HLA-DRB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ATP6V1A ATP6V1E1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HLA-DQA1 HLA-DQB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SEC61A1 SEC61B â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ATP6V1A ATP6V1D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ATP6V1D ATP6V1E1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
NFYB NFYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CYCS APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 11753565 10393175 10364241 15829969 16977332 15907471 10722681 9390557 10578178 16713569 9267021 12147322 10206961 10329646 11112785 10940292
CASP3 APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12874265 21827945 11550094
APAF1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 17145710 15829969 15024710 9390557 19494828 11113115 10617566 9539746 10364241 10722681 27476169 21060833 19118655 20829884 16977332 10329646 15210107 10393175 16352606 11242052 14555243 10376594 12773388 10206961 19337385 10428850 9488720 19788417 15262985 9922454 21827945 10749135 9651578 19698783 12792650 9837928 11227497
BCL2 BAD â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10826997 10949026 11342610 11704864 12107820 12175651 12444011 12767520 16931767 17446862 19030972 19641503 21540285 22039431 23064052 23377657 23430059 23850759 8929532 9346240
BCL2 BAD â—¼   PROTEIN_INTERACTION 20.0 1.0 ACSN 10826997 10949026 11342610 11704864 12107820 12175651 12444011 12767520 16931767 17446862 19030972 19641503 21540285 22039431 23064052 23377657 23430059 23850759 8929532 9346240
AKT1 BAD â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10722653 10949026 11715018 11756412 11923280 15169778 15808505 16697215 17052453 17680028 18372248 18570873 18636226 20138985 20214616 20398329 20832730 9812896
RAF1 BAD â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11532940 12107820 12566895 14764585 15516985 19289794 19565474 24027568 8929532 9069260
MAPK8 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 11983683 12189144 14673001 16166315 15526032 29795446 15907327 14967141 15725726 17555943
RAF1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 38.0 1.0 Omnipath 11983683 12444011 10880354 19030972 19667065 22096607 15849194 16931767 17535812 16103085 9381178 23162742 12107820 18402774 12767520 10826997 8929532 8929531 12175651 25241761 19565474 10949026 19165420 9069260 21540285 17242355 23397142 19289794
AKT3 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 9346240 11493700 20398329 21506126 9381178 20028971 12040186 21303971 15280015 20214616 10230394 10558990 8929531 10837486 11882383 10611223 23109003 12954615 22094462 10949026 15023346 17680028 18218901 17270021
AKT1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 137.0 1.0 Omnipath 10880354 19052636 21506126 20028971 21303971 20214616 11994280 8929531 17570479 12832477 17555943 25241761 11715018 18636226 21998731 9812896 17680028 11500364 18385666 18707149 10201527 18218901 11983683 10490655 19030972 19667065 11756412 11020382 16931767 18372248 15808505 20138985 18046313 18669648 19121340 19703413 11714830 10949026 15972258 16341064 10358075 23085457 18220336 10516287 12897128 9580112 9651683 11923280 9346240 16697215 19690332 11493700 15452053 12040186 10826997 12175651 15722337 14737178 11882383 15226424 10521512 15023346 15784622 17052453 16044149 16403219 12444011 20166139 20398329 9381178 11544290 15037618 12767520 15280015 10230394 10558990 15998799 10082559 11577096 10837486 15169778 10611223 23109003 12954615 22094462 11438654 11312610 11254732 21540285 10383455 19664994 10722653 20832730 18570873 10926925 17270021
AKT2 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 9346240 11493700 20398329 21506126 9381178 15452053 20028971 12040186 21303971 15280015 20214616 10230394 10558990 8929531 10837486 11882383 10611223 12954615 22094462 10949026 11438654 17680028 10516287 18218901 17270021
BAD BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 9305851 17145710 11483855 16697956 9463381 15694340 15849194 20603619 15990872 11583631 8929531 7834748 9388232 17446862 19168699
BCL2 BAX â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11704864 16227588 17446862 17891140 20709625 21641962 22039431 23064052 23377657 23430059 23850759 7644501 8358790 8929532 9872359
BCL2 BAX â—¼   PROTEIN_INTERACTION 15.0 1.0 ACSN 11704864 16227588 17446862 17891140 20709625 21641962 22039431 23064052 23377657 23430059 23850759 7644501 8358790 8929532 9872359
RELA BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18034190 18158998 20056115
BID BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 20956295 17289999 25241761 19968986 15574335 10629050 19062087 10949027 12242151 23374347 14730312 17520191 8918887
MAPK8 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15525785 18471544 16709574
AKT1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 26763134 14766748 15642728 17525161
BCL2 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 22705850 18981409 9463381 21458670 17097560 17525735 8358790 10620799 26004684 29749471 9388232 21199865 17525161 22262057 21778226 15486085 17289999 9111042 12419244 9194558 15231068 10716992 8183370 14980220 9115213 21671007 16642033 23479509 10677502
BAX CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9461218 10629050 20709625 9843949 11326099 12232790
BCL2 RAF1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11463391 11463392 11532940 11704864 12566895 12667443 14764585 15516985 17446862 19289794 19565474 22039431 23064052 23377657 23430059 23850759 24027568 8929532 9069260 9872359
RELA BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17673602 18031796 12835724 15120608 20332461 14978135 20446017 18566231 19259124 14739605 21503108 20103608 17098279 18158998 19233129 16022909 18761399 18191642 21224428 16453001
CASP3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10409669 9395403 20139069 11948397
MAPK3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9115213 10669763 9735392 11323415 21785723 9738012 10677502 23272207 25826088
AKT1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 20398329 21506126 20028971 12040186 18218901
MAPK1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 9115213 10567572 12039864 10669763 15225643 11323415 21785723 9738012 11337027 10677502 23272207
CREBBP BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9829964 10753867 17565603 15337521 10454566
MAPK14 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 29050237 16714293 19336399 11495898
MAPK8 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 12421819 26609913 17097560 16738310 21726807 10567572 21993018 29950132 20919655 22848813 15225643 19029119 9738012 18570871 9115213 12039864 11323415 15733859 18471544 15703383 23329792 10677502
AKT3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 20398329 21506126 20028971 12040186 18218901
BCL2 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16183855 11406564
BCL2 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 18835031 17145710 9463381 16697956 17289999 19074266 12624108 11583631 9727491 15520201 8918887
CTSD BID â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10364179 10805722 11085742 11085743 11832478 12776207 16237087 18955971 22439866 9727492
MAPK8 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18594987 25326334 25077544 27374471
CASP3 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9727492 10364179 10805722 11832478 11085742 11085743
CASP8 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 9727492 10364179 10805722 11832478 12196516 18458084 9727491 11085742 11085743 12097160 9873064
CASP10 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11717445 8755496 9765224
MAPK14 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 14970175 33176141 29414778
CASP8 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 15755874 17179148 9501089 9950028 18669646 23308069 10988287 18458084 16964285 9885230 9765224 11437602 15014070 21295084 8962078 9208847
CASP9 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10708865 9390557 10508159 11230124 18723680 15657060 16977332 15507451 1067155 9708736 25241761 8900201 11242052 9765224 17437405 19788417 9812896 12620238 15941357 12181739 19465923 12792650 15725726
CASP3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17544405 12124386 10579725
CASP9 CYCS â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9390557 25313070 20462491 27697150
AKT1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 42.0 1.0 Omnipath 11756412 11923280 16697215 20398329 18372248 15004527 15808505 20138985 20214616 15703181 17570479 28177918 18840507 15169778 11714830 10949026 16341064 11715018 18636226 10529400 9812896 17680028 19440551 10722653 20832730 18570873 17052453
AKT2 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9812896 15004527
AKT3 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9812896
CYCS CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19788417 16977332 9390557 16713569 12147322 12773388 10329646 12792650 15210107
MAPK3 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 38.0 1.0 Omnipath 15547943 20080742 29416675 12040186 15173823 12697810 11940578 19081073 19586613 16227978 12738796 16039586 17466630 17255949 18669648 15187187 19016842 19541618 19091303 19565474 17052211 18039929 18775330 10601235 12792650 11431469
MAPK1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 44.0 1.0 Omnipath 15547943 20080742 12040186 18083711 15173823 12697810 11940578 19081073 19586613 16227978 12738796 16039586 17466630 17255949 18669648 16888006 15187187 19016842 19541618 19091303 19565474 17052211 18039929 18775330 10601235 12792650 11431469
CD74 HLA-DMB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
CD74 HLA-DMA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
CD74 HLA-DOB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
CD74 HLA-DOA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
CTSS CD74 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10072073 10562280 16286017 22157818 22424724
CD74 CTSS â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 11684289 12078484 12748383 8687433
CEBPG SFTPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11912209 11596110
CEBPG IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9916895 10841183 18247123 19806478 11474579 8999951 18438857
CEBPG IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 12177065 22389450 9655919 12219016 15389813 9621116 12200447 14754879 9950766 12626566 15158360 22558159 14600152 16798734 12215492 12115737 19782405
IFNG EP300 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
AKT2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17964260 16926151
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
EP300 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19608861 25400040 11567019 12419806 17617622 11533489 20333651 12456660 15152190 16846590 9096323 20064247 16382138 16713569 15171256 16135789
RELA IL1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 27371733 21131967 23195252 17612514 27076634 21106671
RAF1 MAPK1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
MAPK1 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
KSR1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19219045 19541618 8226933 10567369 1330321 7992057 9858547 8248196
MAPK14 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15187187 21675959 18039929 12738796 11157753 22521293 17255949 11238443 11274345 12697810
MAPK13 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16009338 12213825 8384717 10995751 12048245 15878863 21980398 19443782 17570479 19413330 19723873 15367685
MAPK1 SPHK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17311928
MAPK1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 17081983 18767875 15849194 19690332 11409918 14654779 23331499 23180781 8226933 20068231 18988627 21917714 18669648 19541618 18691976 16407412 19933846 9922370 15664191 8388392 19651622 10801873 8349614 18775330 9604935
MAPK1 CIITA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15210796 17095509 18245089
MAPK1 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 24342355 17290218
MAPK1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15073167 16888388 16691505
NCF2 MAPK14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16778989 25877926 14530365 27558335
NCF4 MAPK14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16778989 25877926 14530365 27558335
PPM1D MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12758252 15659558 11101524 19713933
RIPK2 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17965022 15692051 17947236 26538579
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK14 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14970175
MAPK14 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12842894 15128824 15485852 10521409 15489227 15849198 15212693 12767944
MAPK14 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 11175347 12356771 15733869 11160957 11532940 7958915 9829964 12235136 16189514 11335727 9687510 8887554 11698596 23532963 8688081 9528766 11018520 11969286 11377386 11909979
MAPK14 EEA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16138080
RAF1 MAPK3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
MAPK3 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
MAPK11 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
KSR1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19219045 19541618 8226933 10567369 1330321 7992057 8248196
MAPK13 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK3 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 16009338 12213825 8384717 10995751 12048245 15878863 19327116 19443782 15212693 15367685
MAPK3 CIITA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 26181363 17095509 20538595 18245089 15210796
MAPK3 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 24342355 17290218 26036637 29233910 24484936 20937773
MAPK3 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 14654779 23331499 19541618 18691976 16407412 19933846 9446616 9922370 15664191 18988627
FCER1G HLA-G â—¼   PHYSICAL_INTERACTION 29.0 1.0 ACSN 10562324 10925299 11353765 11385609 11438547 11489965 11513144 11875494 11994457 12055234 12731048 12811837 15081523 15778339 16287995 16713974 17100877 20435894 20814939 21059766 22267813 23414611 23508573 24378531 8478617 9603467 9625766 9738502 9751747
FCER1G FCAR â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 12731048 15081523 15099567 20814939 23414611 2451784 7590867 9625766 9952373
FCER1G HLA-G â—¼   SHARES_COMPLEX 29.0 1.0 ACSN 10562324 10925299 11353765 11385609 11438547 11489965 11513144 11875494 11994457 12055234 12731048 12811837 15081523 15778339 16287995 16713974 17100877 20435894 20814939 21059766 22267813 23414611 23508573 24378531 8478617 9603467 9625766 9738502 9751747
FCER1G FCAR â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 12731048 15081523 15099567 20814939 23414611 2451784 7590867 9625766 9952373
FCER1G IL6 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12731048 15081523 15099567 20814939 23414611 2451784 7590867 9625766 9952373
FCER1G IFNG â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
FCER1G SYK â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12731048 15081523 15099567 20814939 23414611 2451784 7590867 9625766 9952373
HLA-E FCER1G â—¼   DOWN_REGULATES ✅ - 12.0 1.0 ACSN 10358164 11015446 11062502 12731048 15120186 15536084 22464172 2731048 8478617 9485206 9486650 9655483
FCER1G HLA-G â—¼   DOWN_REGULATES ✅ - 29.0 1.0 ACSN 10562324 10925299 11353765 11385609 11438547 11489965 11513144 11875494 11994457 12055234 12731048 12811837 15081523 15778339 16287995 16713974 17100877 20435894 20814939 21059766 22267813 23414611 23508573 24378531 8478617 9603467 9625766 9738502 9751747
FCER1G SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9280292 17145710 8071371 8810294 8663460
JAK1 IL10 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
IL10 IL10RB â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
IL10 IL10RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
JAK1 IL10 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
IL10 IL10RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
IL10 IL10RB â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
JAK1 IL10 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
TIRAP IL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CREB1 IL10 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11579131 15187187 15749884 16007092 16713974 17404308 20547845
IRAK2 IL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CD14 IL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 IL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IFNG IL10 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
IL10 THBS1 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10433356 10542212 10623821 10925299 11207245 11438547 11875494 12193690 12811837 12818165 14607900 15282297 15579430 15749903 15833879 16200688 16424049 16713974 17404308 17485448 20184663 20435894 20547845 21115385 21191065 21220452 23124025 23508573 24378531 26755705 9834059
RELA IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18760861 9310124 19124729 19122653 18077329 22070873 27324129
CEBPB IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24715531 17525287 12493739 12847250 16413748
CREB1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 22140263 26408955 21986577 19564345 12493739 22116830 10540320 18263767 17202341
IL10 IL10RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17208301 23331499 9312047 12974481 20462497 11485736 10347215 12513909 11035029
IL10 IL10RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 17208301 11717514 7759550 23331499 21071413 12974481 8897595 20462497 15837194 10347215 9568901 19161426 8120391 12513909 26260587 10788470 11591769 11485736 8248239 10231374
CALM3 CAMK2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 3006921 17353931 20668654
ITGB2 CD14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10201950 16751103 3537192 2462607
C3 ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 4062888 26293614
TLR2 SFTPA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16834340 12817025 16213021 11724772
TLR4 SFTPA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16834340 16754682 16213021 18990700
CALM1 RAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22944912 21299499 21730051 9199170
CALM1 CAMK2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 3006921 17353931 20668654
RAC1 ACTG1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 18391171 16262445 11231582 9600938 15040784 12743368
CALM2 CAMK2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 3006921 17353931 20668654
ITGAV ITGB5 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
ITGAV ITGB5 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
PLAUR ITGB5 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
JAK1 ITGB5 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
PLAU ITGB5 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
ITGB5 ITGA2 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 22470492 24309651 26519775 9295024 9763615
CEBPB C3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25617152 22171262 21308746 18247123 10594926
C3 CR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10382758 2551147 9988761 2141838
C3 ITGAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 4062888 16857732 7512600 7679388 12554829
C3 ITGAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 4062888 11073102 26293614
TLR4 FADD â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 21737330 15814722 19278658 12620240 20308068 12181749
CASP8 FADD â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CD14 FADD â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 21737330 15814722 19278658 12620240 20308068 12181749
FADD CASP8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
FADD CASP8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
FADD CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 82.0 1.0 Omnipath 22864571 17145710 11717445 19524512 34591612 15280356 17047155 27552911 12911633 25043603 21458669 11788820 19176810 21525013 21988832 22179575 25939870 12702723 21737330 21741934 26437781 25911380 9228018 21785459 20829884 23972990 21620750 12220669 9774341 17159907 10521396 27321185 17290218 27560715 20103630 24098568 20203691 14612908 8681377 18485876 12107169 15659383 22421964 20448643 9343261 20125124 8681376 12887920 19060883 21737329 23142077 22173242 26972597 22274400 19935698 16410793
FADD CASP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 16585540 17145710 15069192 12887920 9045686 11717445 9228018 20829884 15659383
ITGAV ITGB3 â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
ITGAV ITGB3 â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
FCGR1A SYK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8226994 18818202 8862523 8340414 7522622 7530449 9314552
SYK CD36 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10358164 11907067 12524384 14568985 15536084 17101731 19909365 20150200015 21149606 21378271 21910624 23609447 23896411 8189062 8226994 9000133 9295024 9314552 9396765 9632805 9763615
SYK CD36 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10358164 11907067 12524384 14568985 15536084 17101731 19909365 20150200015 21149606 21378271 21910624 23609447 23896411 8189062 8226994 9000133 9295024 9314552 9396765 9632805 9763615
FCAR SYK â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12731048 15081523 15099567 20814939 23414611 2451784 7590867 9625766 9952373
HLA-E SYK â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11015446 12731048 20814939 23715743 24586048 2731048 9486650 9625766 9655483
SYK CD36 â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10358164 11907067 12524384 14568985 15536084 17101731 19909365 20150200015 21149606 21378271 21910624 23609447 23896411 8189062 8226994 9000133 9295024 9314552 9396765 9632805 9763615
SRC SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7513017 17353363 17570479 16189514 9389695 23100514
SYK FCGR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9280292 9632805 11141335 15136586 8756631 9295288 8663460 9268059
SYK FCGR2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8756631
SYK ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17353363 18088087 11940607 15699036 11042121 8631894 11723131 11719224
ITGB1 ITGA5 â—¼   PHYSICAL_INTERACTION 29.0 1.0 ACSN 10461188 10545505 10559936 10613909 11340065 11413130 11950587 12731048 15866889 16076871 16919435 17522712 18037882 19161977 19339212 19454690 19487819 20644254 20814939 22067905 22154077 22470492 24202395 7529872 7657702 9003039 9456329 9763606 9973479
ITGB1 ITGA5 â—¼   PROTEIN_INTERACTION 29.0 1.0 ACSN 10461188 10545505 10559936 10613909 11340065 11413130 11950587 12731048 15866889 16076871 16919435 17522712 18037882 19161977 19339212 19454690 19487819 20644254 20814939 22067905 22154077 22470492 24202395 7529872 7657702 9003039 9456329 9763606 9973479
THBS1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15292271
BCL10 MALT1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11280761 11356195 11460167 12356734 14660645 16809782 16818229 17052756 17301840 17363905 17462996 17948050 18264101 18264787 20685844 21133840 21199863 21232017 21873235 24560716 24699077 24958845
BCL10 MALT1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11280761 11356195 11460167 12356734 14660645 16809782 16818229 17052756 17301840 17363905 17462996 17948050 18264101 18264787 20685844 21133840 21199863 21232017 21873235 24560716 24699077 24958845
CARD9 BCL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 28765954 11053425 22423967
RIPK2 BCL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 14638696 10825200 14695475
IFNB1 JAK1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15312780 9121453 10395669 9334213 15778442 12842042 17969444
IFNG JAK1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 16467876 7617032 7673114 12438563 10986460 7615558 1396683 8550631
JAK1 PLAU â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
JAK1 IFNGR2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 IL10RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
JAK1 JAK2 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
JAK1 IL6 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
JAK1 IL10RB â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
JAK1 IFNG â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 PLAUR â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
JAK1 IFNGR1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 JAK2 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
JAK1 IFNG â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 IL10RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
JAK1 PLAUR â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
JAK1 IL6 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
JAK1 IL10RB â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
JAK1 IFNGR1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 IFNGR2 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 PLAU â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
JAK1 IL6 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
JAK1 IL18 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
JAK1 IL10RB â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
JAK1 IL10RA â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
JAK1 IL23A â—¼   DOWN_REGULATES ✅ - 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
IL10RA JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26260587 12374810 23331499 12133952 23180781 12974481 10433356 10347215
JAK1 IFNGR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12133952 8232552 8550631 8156998 7796299 7615558 8649432 19041276
PLAU PLAUR â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
PLAU PLAUR â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
RELA PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11689575 20352621 18226221 19165610 22797919 20018891 10467400 9914486 17407600
PLAU PLAUR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 3031025 16879932 3023326 11501527 18376415 16189514 19017363 16456079
CD14 IRAK4 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 19592493 20485341 11960013 18829464 12297423 19498957
TLR2 IRAK4 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 19592493 20485341 11960013 18829464 12297423 19498957
CD36 IRAK4 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 19592493 20485341 11960013 18829464 12297423 19498957
IRAK4 IRAK1 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26885855 27048821 27066895 9469432
IRAK4 IL18 â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 14504095 14660645 14662834 15099563 15802534 16878026 17704786 23681101 23811849 26885855 27048821 27066895 9469432
IRAK4 IRAK2 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 TIRAP â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 CD14 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 TIRAP â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 CD14 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 IL18 â—¼   SHARES_COMPLEX 18.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 14504095 14660645 14662834 15099563 15802534 16878026 17704786 23681101 23811849 26885855 27048821 27066895 9469432
IRAK4 IRAK1 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26885855 27048821 27066895 9469432
IRAK4 IRAK2 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 IRAK1 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26885855 27048821 27066895 9469432
IRAK4 IL23A â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 IL6 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 17145710 17785851 18252867 17276401 16024789 14625308 15084582 21903422 15292196 25452754 19775907 18221795 15905496 19166926 12538665 12860405 14751757 12496252 11960013 24735611 26143580 17337443
IFNG IFNGR1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK2 IFNGR1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
IFNGR1 IFNGR2 â—¼   PHYSICAL_INTERACTION 42.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 22003200 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK2 IFNGR1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
IFNG IFNGR1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
IFNGR1 IFNGR2 â—¼   SHARES_COMPLEX 42.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 22003200 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
IFNG IFNGR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 16110316 12915721 12438563 7514165 15530433 23331499 16237089 23898330 9111318 15143187 16467876 10986460 18988627 1396683 8550631 20304997 11250200 10860730 12165521 29145629 10811850 7617032 18591661 8631301 7615558 7510216 7673114
IFNGR1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 11438544 15864272 17063185 23898330 12040185 7499845
JAK2 IFNG â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
IFNG IFNGR2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK2 IFNG â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
IFNG IFNGR2 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
HLA-G IFNG â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
IFNG RELA â—¼   ENZYMATIC_REACTION ✅ 48.0 1.0 ACSN 10485906 10679398 11489965 11579131 11777960 11870632 11964313 12133954 12413632 12759422 12818165 14607900 14668329 15079071 15536066 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17145890 17404308 17550372 17559085 1825141 18272812 19171876 19833085 20038811 20138012 20819927 21149606 21224476 21411734 23430059 24658051 26755705 2965306 6425450 8383323 8580069 8641346 9743347 9834059 9864217
IFNG TLR4 â—¼   ENZYMATIC_REACTION ✅ 41.0 1.0 ACSN 10485906 11489965 11579131 11672593 11777960 11870632 11964313 12032143 12413632 12811837 12818165 14607900 15634932 15644117 15778339 15811952 15814715 16286920 16306937 16424049 16713974 16917499 17016554 17114424 17559085 1825141 18272812 19833085 20038811 20154735 20547845 20819927 21149606 21411734 23508573 24658051 26755705 2965306 6425450 9834059 9864217
IFNG TLR2 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10485906 11489965 11579131 11672593 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16267105 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
RELA IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17035338 12759422 12105194 21243522 9374532 10227974 20643337 19929594 19732956 21224476 23195252 23667107 12842891 14662860 12757742 18690006 17407192 10075983
CREB1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20979795 11907114 20006311 12928400 16713974 22413812 7759501 12626576 9834094 15879136 20685939 18641343 9503023
CEBPB IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10995751 15878863 16331681 17556653 19521987 11312260 11009091 8634139
IFNG IFNGR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 12915721 7673114 7514165 12438563 15530433 23331499 16237089 9111318 15143187 16467876 10986460 18988627 1396683 8550631 29145629 10811850 7617032 18591661 8631301 7615558 7510216 20304997
JAK2 IFNGR2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK2 IL6 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
JAK2 IL6 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
JAK2 IFNGR2 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
SRC JAK2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
JAK2 IL18 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
JAK2 IL6 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
JAK2 IL23A â—¼   DOWN_REGULATES ✅ - 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
IL1B JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10198225 7528775 9038232 8943050 9454765 7594594
IFNGR2 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7901766 23331499 23898330 7514165 16381926
PTPN1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23331499 18988627 15780598 15821101 12748279 11694501 11970899 11970898 21806020
JAK2 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 11134016 8876196 9689060 10205168
IRAK2 IL6 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CD14 IL6 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
FCAR IL6 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12731048 15081523 15099567 20814939 23414611 2451784 7590867 9625766 9952373
TIRAP IL6 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IL6 CEBPB â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 11306493 15099563 15356132 15573129 18209571 18555777 18555778 19581928 20138012 23034983 23567181 24011634 24346288 25002027 25582338 26201938 26268945 27557510 7590867 8837607 9845545
RELA IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 114.0 1.0 Omnipath 26596471 19124729 10373597 9523851 23595969 28270510 21537341 17982049 15226358 18243142 12200447 20371366 24664372 23874122 14532843 18942706 10975857 21278793 10469356 22547075 17490702 11459775 23335080 10569191 19707556 19687301 7499267 8290595 23857586 24676671 18061164 11058167 12887736 15013753 15158360 22661093 20935672 20511231 17350185 10903137 16112536 27413250 21810609 16984731 16166627 18469854 12881425 24012417 23386688 22105366 8752656 12176740 27371733 22578249 18057724 20351184 10329846 19164127 10542237 11564778 20221401 15517885 19122653 20534538 7876168 27211851 9516466 18996370 8824277 18310089 21104991 25888873 12359431 11327783 20066113 20100571 19703987 19469019 21106671 16960103 18502099 16043358 21996739 20650996 22021035 11120852 12672795 12058956 18483242 22189669 14976218 17495236 11007957 21131967 11975924 27337441 9182853 10963848 17040605 11504280 15756023 10823821 17932106 19966855 20696864 12177065 8679226 9199307 17196927 20457835 21098092 17532054
CEBPB IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 8441418 10748205 21069809 1327803 7543095 11004486 9312180 23595969 15389813 12853840 7651415 7744000 9523851 19026986 17332680 8786324 8910763 11250916 23361365 11114305 7821611 21127061 9516466 10816606 1730090 8234276 15044620 9282937 16784777 20511231 1427600 24472318 7818522 10903137 23874122 8336793 22558159 14600152 19632992 9661072 14530280 1421375 11160296 9182853 22895549 25382637 9378980 9648065 24012417 11866474 8725624 12177065 8752656 11035101 18955501 2112087 15613028 9442386 9199508 7744784 15688424 8346247 22074460 17955490 12706815 11594800 11120852 10435001 8325885 19782405
CREB1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 8725624 19342597 20100571 20160059 11701462 16424113 18617614 19162127 15467434 21209948 23874122 17495236
CYBA RAC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16636067 18347018 12716910 16329988 16762923
CYBA CYBB â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBA NCF2 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBA RAC2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11145705 1660188 18347018 11090627 10455184
CYBA NCF4 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBA CYBB â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBA NCF4 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBA NCF2 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
RAF1 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
AKT1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 51.0 1.0 Omnipath 19197339 11971957 18767875 20230923 10576742 20068231 17570479 16189514 18669648 25241761 18691976 10576741 10618391 20688159 21745501 12087097 12801936 12048182 22798428 16854453 19058874 11997508
KSR1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 7477354 12932319 9665134 9094715 19766101 23331499 8601312 19595761 11478855 8332195 15520859 8503013 16093354 19541618 19933846 10205168 7760835 18775988 18789263 11134016 8180183 1990291
SRC RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 7692235 12551923 7517401 17097642 15258589 9689060 16189514 16630891 10998357 11376654 29063113 8876196 10205168 28846113 12952943 22592532 11134016 15710605 16170185
TLR4 CASP8 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 21737330 12752666 15814722 16115877 14739303 21737329
CD14 CASP8 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 21737330 12752666 15814722 16115877 14739303 21737329
SRC CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 27432652 16619028 19470771 27109099 27195913 19383910 30501030 24100030 22074016
CASP8 CASP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 22864571 17159907 17145710 12887920 11832478 11717445 21737330 15280356 12198154 3031469 15659383 170210 8962078 22421964
CREB1 RELA â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
CREB1 RELA â—¼   PROTEIN_INTERACTION 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
CREB1 RELA â—¼   DOWN_REGULATES ✅ - 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
RELA IL12B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 12820969 14688340 20221401 11058167 10657616 10940886 19122653 18690006 11792125 19624579 17982049 9464836 17924060 7565674 14976188 15251981 12077291 17579043 24012417 19299558 16166378 12517966 17635610 24184907 15270850 20876114 9808189
RELA AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20186924 18031796 20649564
RELA IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 26596471 27338466 11114294 8413223 20975042 17707233 23383347 11058167 12686724 16433741 23667107 15382119 19122653 24009751 27211851 18566416 15292915 20617571 23056550 12517972 18285351 19843519 22267743 15812237 25161822 22388040 8021507 9878621 14960579 10963848 23195252 11395507 27534992 9058643 15543947 19846753 20696864 8679226 24908318 28389361 27371733 15972680 20336759 10080875 17082635
RELA IL23A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17982049 20228197 17707233 20876114 19122653 17569750 21097874 19624579 18375954 19185846 19592489 17182554
RELA IL12A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 14568984 17982049 17579043 20876114 19122653 22070873 18690006 19164128 19185846
RELA IFNA13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7957928 15331713 9446577 8035474
RELA IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 23932714 15955070 22547704 19570999 10074115 21209118 17079305 7799921 17496231 15699120 12077266 8035474 17785777 12005436 24185615 10848607 16125763 9446577 20855868 24656046 23857586
CREBBP RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10542243 14597638 18241676 17138826 15140884 9096323 16713569 12456660 10454579 16382138 19608861 9806899 25314079 11931769 12163591 12881425 9659924 15171256 9548485 16291753 17362989 25733689 17434128 15334063 15806143 10235267 17296604
IL1B RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25606026 26999213 22240205 23666959 19197368 25306394 24009751
TLR2 CD14 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16455995 17889651 10426996 15241424 16880211
TLR4 CD14 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 22078883 16467847 22158869 18233961 18297073 14517279
IRAK2 CD14 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 21606490 11544529 17890055 19679662 20485341 17878161 16024789 19224918 20400509
CD14 IRAK2 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CD14 IRAK1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 21606490 11544529 17890055 19679662 20485341 17878161 16024789 19224918 20400509
CD14 TIRAP â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CD14 ITGAM â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10201950 16751103 3537192 2462607
CD14 TIRAP â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CD14 IRAK2 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CD14 IRAK1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CD14 IL23A â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
LBP CD14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17535871 2402637 12417309 7583357
CD14 TLR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11745332 17535871 12196527 32196115
CD36 TIRAP â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
TLR2 TIRAP â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
TIRAP IRAK2 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
TIRAP IRAK2 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
TIRAP IL23A â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
TIRAP IRAK1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
TLR2 TIRAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22673208 19717524 22664090 18221795 17258210
TLR4 TIRAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 22139835 19717524 11544529 20048342 21903422 16410796 17258210 14517278 24265315 21829704 18221795 17635639 21873236 11526399 12646618
IL18 IRAK1 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26885855 27048821 27066895 9469432
IL18 IRAK1 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26885855 27048821 27066895 9469432
IL18 IRAK1 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26885855 27048821 27066895 9469432
RFXAP HLA-E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10779326 12618906 9806546 9118943 11258423
TLR4 IRAK2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 21606490 11544529 17890055 19679662 20485341 17878161 16024789 19224918 20400509
TLR4 IRAK1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 21606490 11544529 17890055 19679662 20485341 17878161 16024789 19224918 20400509
TLR4 SFTPD â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16834340 16754682 16213021 18990700
CYBB NCF4 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBB NCF2 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBB RAC2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11145705 1660188 18347018 11090627 10455184
CYBB NCF2 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
CYBB NCF4 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
NCF2 NCF4 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
NCF2 NCF4 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10679059 10714681 11062502 11146654 11385609 11747822 11907067 12626562 12740575 14697347 15169870 15184873 15536084 15927447 17517963 18423981 18809714 19372727 19380816 19732719 21178402 21383238 22157818 22827577 27331412
NCF2 MAPK11 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16778989 25877926 14530365 27558335
RAC1 NCF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9624165 11090627 9642115 25416956 16189514 7738010 25301945 11896062 9255350 8036496
NCF2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 9624165 11090627 9642115 25416956 16189514 7738010 25301945 11896062 9255350 8036496
CEBPB CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17067998 8654374 10818089 15722556 15388792 17599912 12857754
CREB1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 10866654 18599546 15585582 7870178 8028671 11313407 16007092 8413673 11564156 15691881 9829964 15073328 20403362 11259575 17476304 17707401 20541704 16799563 7870179 11123304 27789289 7913207 12933667 8663317 8004670 11483993 12198160 9413984
THBS1 CD36 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 10657674 11982756 14568985 14996710 17101731 20150200015 21378271 22943793 8349738 9295024 9763615
THBS1 CD36 â—¼   PROTEIN_INTERACTION 11.0 1.0 ACSN 10657674 11982756 14568985 14996710 17101731 20150200015 21378271 22943793 8349738 9295024 9763615
THBS1 CD36 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10487979 10772961 1379600 23640500
THBS1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 2478219 14963009
IL10RB IL10RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
IL10RB IL10RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
RAC1 AKT1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
SRC RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22163037 17991704 21798346 26816343 29036929
RAC1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17251915 12213839 18423204 18426980 10592173 22252525 10930450
RAC1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 18000759 20027184 21157483 11756412 11923280 16697215 20398329 17461779 18372248 20338997 15808505 20138985 20214616 21474067 19568798 15169778 19720745 18925875 10949026 11715018 19143635 12393431 18636226 10617634 9812896 17680028 19151919 10722653 20832730 18570873 17052453 12408816 11274345
IRAK2 CD36 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 21606490 11544529 17890055 19679662 20485341 17878161 16024789 19224918 20400509
TLR2 CD36 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10549626 22028855 10426996 10364168 16880211 10490993 14977973 11123271 11431423 18178856
CD36 IRAK1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 21606490 11544529 17890055 19679662 20485341 17878161 16024789 19224918 20400509
SRC CLEC7A â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 16341139 10779524 20193029 15845454 21525931
PTPN1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 10698938 25585026 17092689 17974954 16537444 18332219 9600099 15866871 8647855 9261115 11346638 12857726 12468645 11007774 1646596 16115959
ESR2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11013076 12095943 12630920 11032808
SRC ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10330414 17473008 8631894 18156175 25694433 18840695 18364349 18398066 10592173 16935858 21956114 17353363 18088087 12359711 15212693 14996908 15695822 15699036 11723131 20702409
SRC FCGR2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8756631 17474147 18083107
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
CEBPB IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 21917825 12072435 9372929 16867259 20702408 17283046 10464291 16569740 10801783 15812237 22260630 10841183 10838190 10383163 9376596 17386941 10956548 12759449 11278846 12468538 11035101 11801594 2112087 12355443 15383601 16439360 19806478 22074460 16399630
AKT1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18578522 10896934
AKT1 PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17081983 18691976 11579209 16189514 10480872
AKT1 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11976320
AKT1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11546794 14500673 12176337 11445557 9736715 12149249 11278835
AKT1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11175347 11756412 12356771 15733869 20452955 20398329 11160957 10217147 19216069 20214616 11463845 9829964 7958915 12235136 16680151 17646672 9687510 8887554 11698596 8688081 17680028 9528766 11018520 11969286 12519783 11909979 15725726
HLA-DPA1 CTSS â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 11684289 12078484 12748383 8687433
HLA-DQA1 CTSS â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 11684289 12078484 12748383 8687433
HLA-DRA CTSS â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 11684289 12078484 12748383 8687433
HLA-DQA2 CTSS â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 11684289 12078484 12748383 8687433
IRAK2 TLR2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 21606490 11544529 17890055 19679662 20485341 17878161 16024789 19224918 20400509
IRAK2 IL23A â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK2 IRAK1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK1 IRAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 10383454 21903422 16024789 12138165 24973222
AKT2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
AKT3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
CAMK2D CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11175347 12356771 15733869 22554507 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
CAMK2G CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11175347 12356771 15733869 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
CAMK2A CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 11175347 12356771 15733869 1646483 11160957 9668047 7958915 9829964 12235136 11970864 9687510 8887554 11698596 8688081 9528766 11018520 11969286 11013247 11909979
CAMK2B CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11175347 12356771 15733869 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
CEBPB SFTPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11912209 11596110
CAMK2A CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1314426
TLR2 IRAK1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 21606490 11544529 17890055 19679662 20485341 17878161 16024789 19224918 20400509
HLA-DRA HLA-DOA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DRA HLA-DOB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DRA HLA-DMA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
CIITA HLA-DRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10886240 11889043 11429551 9300692 9600954
NCF4 MAPK11 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16778989 25877926 14530365 27558335
CAMK2A NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12630910 10400690 1375933 10874031
RAC2 NCF4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11145705 1660188 18347018 11090627 10455184
RIPK2 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15692051 17947236 17965022 17186025 26538579
MAPK8 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 28532298 14567915 17496919 19591900 21372320 19788416 15708980 8608010 16984892 20512932 20220133 21438496 20054826 19616017 23762064 15611655
MAPK8 PAX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11700324
HLA-DQA1 HLA-DMA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DPA1 HLA-DMA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA2 HLA-DMA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA1 HLA-DMB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA1 HLA-DOA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA1 HLA-DOB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA2 HLA-DOA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA2 HLA-DOB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA2 HLA-DMB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
CIITA HLA-DMB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11889043 9300700 7495736 9600954 11332992
IL12A IL12B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 10779781 10899108 8943050 7527811
HLA-DOB HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DOA HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DPA1 HLA-DMB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
TLR2 SFTPD â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16834340 12817025 16213021 11724772