CPS1
|
ARAF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216198
12620389
|
ARAF
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18039929
|
EZH2
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23624935
21406404
|
SP3
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20435036
20407012
|
UBE2D2
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
KAT7
|
NFYA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9632821
11744689
|
MAPK3
|
GATA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22227582
11585926
|
CEBPA
|
MYC
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
2.0
|
0.8
|
ACSN
|
11340171
20581311
|
MYC
|
ADM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9973255
15192039
|
MYC
|
EZH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21941025
19197161
|
MYC
|
NFYA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11282029
|
LIAS
|
GCSH
|
â—¼ SULFURTRANSFER
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11389890
22152680
|
CALM1
|
MYH14
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
3079756
3839510
|
CALM1
|
MYH11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
3079756
3839510
|
CALM1
|
ITPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
7755592
10456332
|
SRY
|
NR5A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
30552336
21412441
|
GLI1
|
FMO1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17873912
19095649
|
NAMPT
|
ADORA2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6538693
18486613
|
PRKG1
|
ITPR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18757735
0804738105
|
GAPDH
|
EDN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18809573
|
USF1
|
NFYA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21770893
12697323
|
EZH2
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20574448
|
GATA4
|
SRY
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23102581
18445271
|
ATP5PF
|
ATP5PD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
GATA4
|
NKX2-5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
ADSL
|
GART
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
MYC
|
KAT7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
MYC
|
LBR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17353931
29467282
|
NFYA
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11777930
16713569
|
BRCA1
|
EZH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
25531315
23624935
|
EGFR
|
GAPDH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
NDUFA2
|
NDUFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
CACNA1S
|
CALM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CALM1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
CALM1
|
CAMK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
MYC
|
AMD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12646176
11916966
16713569
20215511
9788437
30415952
14612409
|
EZH2
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19079346
20574448
|
MAPK3
|
MAP2K2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10567369
19219045
8013650
|
MAPK3
|
SP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17685427
|
MAPK3
|
ALOX5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12670876
12205041
|
MYC
|
CMAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
GAPDH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
AMPD2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
ALG5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
FPGS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
FUT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
ATP1A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
LBR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
CEBPA
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12873812
|
MYC
|
CYCS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12533512
18046414
17093053
|
MYC
|
CEBPA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12873812
|
DBT
|
GCSH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
24256811
10103005
24341803
|
CALM1
|
CAMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7559563
12475216
20668654
|
NR5A1
|
CGA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12193378
12920232
14596681
|
FOXA2
|
CEBPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19074951
|
CEBPA
|
CPS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
1511897
9774647
19272383
|
GNA13
|
ARHGEF11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11799111
10026210
|
GNA13
|
ARHGEF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11313914
15951850
22661716
|
NFYA
|
SP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16024108
|
VDR
|
ALOX5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19837082
|
NDUFAF1
|
NDUFAF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
MAP2K2
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
ARAF
|
MAP2K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
ADM
|
CALCRL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
ALG3
|
ALG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
GART
|
MTHFD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ARAF
|
MAP2K2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
21988832
18039929
24746704
16189514
32296183
25852190
21779497
11909642
|
MYC
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12032322
19882681
20940401
10375022
21668996
11916966
12646176
11983916
|
VDR
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
21458521
16087726
15218361
11967012
|
MAPK3
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
1651322
17081983
3138233
15901825
16785992
1939237
91332050
27531070
17570479
2543683
2115882
34086370
17192257
1651323
15302935
|
MAPK11
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
15187187
18039929
12738796
16932740
11274345
|
EGFR
|
CALM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
17145710
19901323
20029029
12359306
16497976
25402006
17389395
18578522
16799092
20068231
3415247
7925415
18669648
12153558
24658140
17287340
14960328
18707149
17016520
|
MAPK3
|
MAP2K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11802164
15239952
21779496
11802165
15260967
|
MAPK11
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
MAP2K2
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
101.0
|
1.0
|
Omnipath
|
19901323
17081983
11704645
9694850
12750173
1411546
19690332
12932319
18799465
16497976
18083107
11134045
8626767
9006895
17389395
19219045
15342917
9447970
16887817
23331499
17569879
7867743
7559390
21071413
19534553
8226933
20068231
8223433
17272394
93330262
15851026
15811950
26987942
18988627
19494114
18669648
19541618
11242034
15466476
18691976
1381507
17906627
11986622
19933846
8376945
11971971
17192257
11136732
11948414
7898932
7687743
9731057
19651622
11730323
16464493
18983981
11251083
11118451
15580310
19369195
18707149
12920017
15951569
15466214
10746662
15212693
|
MAPK13
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
MAPK3
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
18463697
9155018
21071413
32482868
18988627
15210690
|
MAPK3
|
CEBPA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
20101026
14701740
26515730
|
MAPK3
|
CAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17206380
25472841
12438317
15890648
|
MYC
|
GAPDH
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
11274345
11283613
11283614
11704864
15199147
17055429
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
25002027
28536364
|
MYC
|
GPI
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10823814
11274345
11283613
11283614
11704864
16126909
17055429
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
25002027
28536364
|
MYC
|
CEBPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
15681429
17082780
7556187
8076602
20097210
12695333
15867211
19259613
|
MYC
|
CAD
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
7739536
10931841
11673469
10657901
12177005
14519204
9111322
9811896
10567564
17706770
24771621
11983916
|
MYC
|
MTHFD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12747840
12808131
18414489
|
MYC
|
MGST1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14519204
11983916
12695333
|
MAPK9
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10551811
34160558
26235622
25893300
25438055
20140016
33928666
11243879
|
CALM1
|
GRIN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9952395
8625412
12379661
9728925
|
NPPB
|
NPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7901875
15709752
29934641
1309330
8700153
|
NR5A1
|
SRY
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11207191
19457926
12606467
|
NDUFC1
|
NDUFA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA7
|
NDUFA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA2
|
NDUFA7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
NDUFC1
|
NDUFA2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA7
|
NDUFA2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFAF1
|
NDUFA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10465784
15526035
16200211
16218961
17344420
20025615
20816094
25371197
26989860
|
NDUFA7
|
NDUFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA7
|
NDUFC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFAF1
|
NDUFA7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10465784
15526035
16200211
16218961
17344420
20025615
20816094
25371197
26989860
|
NDUFAF1
|
NDUFC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10465784
15526035
16200211
16218961
17344420
20025615
20816094
25371197
26989860
|
GLI1
|
FOXA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
11001584
11274345
16054035
16396903
16406505
16880536
17000779
17439715
17638910
18754008
18813803
19081070
19190345
19219074
20107231
22354771
23031257
26587781
8545107
|
GLI3
|
GLI1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12435627
14723851
10075717
16571352
19667090
|
GLI1
|
FOXA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
18813803
19219074
16406505
16880536
16054035
11001584
17000779
17439715
19190345
8545107
16396903
11274345
20107231
|
USF1
|
CEBPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
22719268
16537832
8076602
21680747
8493090
7862113
8585944
17239350
|
CEBPA
|
GAPDH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12842822
7864870
|
ADM
|
CALCRL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11693189
10347248
9620797
|
MAPK11
|
MAP2K2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
GNA13
|
ARHGEF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
14607242
9641916
9641915
16189514
12681510
|
NKX2-5
|
GATA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19479054
15653675
16137232
|
GATA4
|
EDN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10788492
19546173
18252717
11739382
11435416
12724418
|
MYH11
|
MYH14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9354661
8662509
11331307
11942626
|