Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PML ELF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14976184
RRBP1 ZNF518A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RRBP1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TRIP12 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SP1 YY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22553354
ATF7IP ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ACTB POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10773068 435297
ATF5 DISC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12812986
ATF7IP ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
HEYL ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD4 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
DMTF1 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21421563
PIAS3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 14691252
KLF3 KLF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18687676
SP1 KLF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18353772
ATF7IP FLT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
CADM1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SP1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212972 10976766
SP1 RPS3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12463423
SP1 LAMC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12034813 9403717
SP1 PKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17890878
HLA-B ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ATF7IP CSPG4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SUMO2 LAMA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 ELF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16904644
ZNF350 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
MACF1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SVEP1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
COL4A2 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
CEP250 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
DMTF1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
NOMO1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
NPR1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
H1-1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PCDH1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
MCAM ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
LUC7L2 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
STBD1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PKD1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
GMEB1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
MRI1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
KIF13A ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SENP3 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
LAMA4 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PEX6 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
MED4 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PAPPA ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ATF7IP LAMC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ATF7IP PIAS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ATF7IP SUSD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ATF7IP CDH11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ATF7IP ZNF518A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ATF7IP RPS3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ATF7IP FLNB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ATF7IP LAMA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ATF7IP PLEKHB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ATF7IP TTC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ATF7IP SPTBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SPTBN1 RPS3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNF4A PKD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12048202 22178500
HNF4A SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15651981 16713569 19115260
MACF1 DISC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
ATF7IP SP1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HNF4A SUMO2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 35140242 22505616
SUMO2 PIAS3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21693764 19217413 19471022 16524884
GTF2E1 GTF2E2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
RRBP1 DISC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31413325 29961565
ATF7IP SUMO2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
SUMO2 PML â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17000644 16189514 23543742 28851805 19553342 21148299 22155184 24190887 20826694 21779164 22578841 17081986 21693764 24637324 15940266 20797634 9452416 19471022 16713569 25027693 21252943
SENP3 SUMO2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19394292 25027693 16608850 11029585
LAMA5 LAMC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14681455 11133776 25241761 26344197
SP1 YY1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PIAS3 SMAD4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 14691252
ACTB POLR2A â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
SP1 SMAD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10878024 18215124 21297662 16714330 11114293 22033265
HNF1B HNF1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 2044952 35140242 33961781 10484768
MAPK3 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15093545
SP1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9819401 21360626 24728382 16713569
SP1 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21421563
SP1 KLF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18353772
SP1 PKD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15770226 18922886 17890878
SUMO2 SETDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LUC7L2 SETDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ARL14EP ATF7IP â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
ERCC2 POLR2A â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ATF7IP SETDB1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
ERCC3 POLR2A â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
LAMA5 LAMC1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
ERCC3 ERCC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15220921 9118947 8652557 19934020 16669699 33381997 8152490 22939629 22678362 26340423 27193682
GTF2E1 POLR2A â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
GTF2E2 POLR2A â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
ERCC2 GTF2E1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
ERCC2 GTF2E2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
ERCC3 GTF2E2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ERCC3 GTF2E1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ERCC2 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ERCC2 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10734072 8652557 10024882 16669699
ERCC3 GTF2E2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
ERCC3 GTF2E1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
SP1 FMR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10612627 16886907 9328468 15479157 15175277 16500891
MAPK3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 32205409 20150555 21983342 11904305 14593115 18199680 8226933 14744793 16079281 19318349 20882567 22266860 28574228 21097497 8388392 32615164 16377629 19245816 18775330 9604935 15212693
MAPK3 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12721286 14517250 14662762
MAPK3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 28115363 12801888
SMAD4 SP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SP1 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19540905 15651981 23307400
SP1 NPR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20864529 10098505 24451378 11022037
SENP3 SUMO2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19394292 11029585
HNF1B HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10518495 8290348 11585914 16479257
HNF4A HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8367288 9111350 9792724 8674436 11717395 9313764 9837989 9204893 9232592 1734282 20850486 8735941 11145965 11085951 10331424 8808405 12601360 16670373
HNF1B HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15486044 1363228 16793932 15001636
MBD1 SETDB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15691849 15327775 17066076
MBD1 SETDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15327775 17066076