Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
RACGAP1 CDK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18201571 6166552
PBK CDK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 10779557 5212518
KRT20 FXR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CCDC85B FXR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LDOC1 FXR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR2 SF3B2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 AXIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 TRIM37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PBK TRIM37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
E2F4 PBK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15782160 18319725
PRC1 PLK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000110 19468300
RACGAP1 PLK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19468302 1000111
RACGAP1 PLK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 1000110 19468300
PLK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 7266226 19833129
E2F4 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15510213 18319725
TP53 E2F4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15574328 24096481
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
TP53 GSK3B â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5216887 14744935
TP53 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
TP53 PRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15531928
KRT20 CCDC85B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRT20 PRC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LDOC1 CCDC85B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CCDC85B CHCHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CHCHD3 PRC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CHCHD3 CCDC85B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CCDC85B PRC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
E2F4 PRC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799066
GSK3B AXIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219694 17318191
EPB41L2 PRC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SHANK3 PRC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
USHBP1 PRC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TRIM37 PRC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PRC1 TRIM37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GSK3B CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219694 17318191
GSK3B CCNE1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25241761 14536078 8861947
BRCA1 KIF23 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
CDK2 CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 21319273
CDK2 E2F4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25852190
FXR2 PRC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30217970 31586073
TNR3 PLK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
EXOS2 PRC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ARHGH PRC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32203420 31586073
PTBP3 PRC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22575643 31586073
PRC1 ACSM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PRC1 SPF45 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34133714 31586073
PRC1 SF3B2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30217970 31586073
PRC1 EXOS8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34133714 31586073
PRC1 NEP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34133714 31586073
PTBP3 SF3B2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 22575643
SPF45 SF3B2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TRI37 DISC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 33961781
RHOB KIF14 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
PRC1 TUBA1B â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
PRC1 TUBB2B â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
GILT BRCA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PLK1 BRCA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25483079 24067368 31730000 29656893
CCNE1 CDK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9053846 9891079 1388288
RHOC RHOA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31871319 33961781 31980649
RHOA ARHGH â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31871319 32203420
GILT PRC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TNR3 PRC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DCTN1 PRC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 31586073 26638075
DCTN1 DISC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
DCTN1 KIF14 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 31586073 26638075
BRCA1 CDK2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PLK1 PRC1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17351640 19468300 31586073
PRC1 RGAP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14744859 31586073
GSK3B CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.84 0.84 Signor 16293724
AXIN1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 7025676 19131971
CDK2 TP53 â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 24173284
PLK1 DCTN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 12852857
RACGAP1 KIF23 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 8397056 22580824
PRC1 KIF4A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15297875 23870126 31586073
GSK3B TP53 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CCNA2 BRCA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25091198 16713569 9244350 10373534
FZR1 PLK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DNMT1 DNMT3B â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
RGAP1 PLK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25486482 19468300 19468302
TRI37 PRC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 16713569 19447967
CCNB1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 11278247 23246971 9244350
E2F4 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21102443 16713569 9244350
CDK1 CCNA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24302728 21308745 26496610 33422522 14681455 23602568 25852190 33961781 12853968 26186194 17679094 32707033 9053846 8463339 19483727
EXOS8 EXOS2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17545563 28514442 26496610 33961781 24981860 26186194 11719186 26344197
AXIN1 APC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16199882 22682247 10228155 29045831 18786926 20128690 19131971 26496610 10811618 9734785 29713058 23277359 17510365
CDK2 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31270457 16713569 10373534 9244350 8764100
DNMT1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19943104 22197621 20631324
CCNB1 CDK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 34224728 18337751 9891079 24508230 17431037 9560267 14681455 17283331 8662825 19162005 16159883 25852190 20360007 19879842 12397081 11331587 9247342 26496610 20228808 25750436 12612082 16784539 23602568 20733055 27626412 20367638 8397206 10973963 9001210 20956543 33037310 8397207 23543736 32707033 2570636 30674583 10716937 27030811 18408765 24358021 20974803 7799941 33961781 26186194 17679094 23799914 8463339 26344197
CDK1 KIF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 29771379
CINP CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16082200 19889979
PBK H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16982762
E2F4 TTK â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17981789 11799066
E2F4 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15510213
E2F4 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15510213 10766737 18319725
AXIN1 GSK3B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 17601533 21988832 10228155 24976009 30181396 20128690 12511557 17318191 16293724 23455922 28546513 17318175 19303846 18632848 19131971 16890161 26496610 23892894 23602568 22613765 18593713 29568061 21242974 22682247 19759537 11738041 22270359 24451375 9734785 32707033 21502811 17510365 10481074 16199882 26912724 23959799 29045831 22509369 29789528 19202075 12584189
PRC1 RAC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
RAC1 KIF14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
PRC1 RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
RHOA KIF14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
KIF23 RGAP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 11782313 26496610 32203420 33961781 31586073 18201571 22939629 11942621 26344197
CIT PRC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
PRC1 RHOB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
PRC1 RHOC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
PRC1 KIF14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
RHOC KIF14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
DNMT1 GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DNMT1 DNMT3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24423239 16481298 20155458
RHOB KIF14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
CIT KIF14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
APC GSK3B â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
PLK1 CCNB1 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 11242082
CDK2 FZR1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CCNE1 CDK1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
TUBA1B TUBB2B â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CCNA2 CDK1 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
CTNNB1 AXIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219694 17318191
CTNNB1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 36950384
CCNB1 CDK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 20733051 28514442 9891079 7799941 8397207 25852190 26496610 33961781 26186194 23602568 10995390 23455922 30674583 18471975
CDK2 CCNE1 â—¼   PHOSPHORYLATION ✅ - 0.96 0.96 Signor 19561641
APC GSK3B â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11166179 29045831 21118991 8638126 11251183 23602568 29568061
CTNNB1 GSK3B â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
CCNB1 FZR1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
CDK2 CCNA2 â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 10652300
CCNB1 CDK2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CCNA2 CDK2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 8475101 28514442 16431923 33854235 11940657 10559988 15189033 17361108 16290148 14681455 17254966 8662825 25852190 15557281 23455922 19483727 18471975 11141566 10924145 15828833 21241890 19631451 11377199 18177895 8684460 26496610 9716181 12853968 11907280 23602568 9724724 15647383 14656438 19773423 12941338 15239650 24302728 25669885 15890360 7630397 8756328 8397207 21447625 22231403 20733051 9660939 24358021 12044161 33422522 11983168 33961781 26186194 7553852 16209941 12244298 9380407 8463339 15455144 10930425
CDK2 CCNE1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 28137908 16431923 29439025 9891079 18559665 33854235 11940657 15004009 17431037 17361108 33854239 14681455 17254967 8867812 23853094 10827081 10330164 8662825 25852190 15557281 9192873 23455922 21092281 14536078 21372285 21241890 19631451 16223725 26496610 1388288 9716181 9472014 15980415 14701826 23602568 8978686 11433299 11132966 24771265 12839982 20587660 19470470 10359664 15514162 17970072 9840943 25728284 9660939 8647086 24358021 7799941 12529437 8756624 33961781 15670215 26186194 20837141 12800980
KIF23 RACGAP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AXIN1 CTNNB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
AXIN1 GSK3B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
APC AXIN1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10421629 10581160 11487578 11955436 11967263 12051714 12554650 15001769 15327768 16039586 16288291 16940750 17143292 17318175 17936032 19619488 19751508 20006983 20705860 22270359 23343194 24023259 25730849 7542250 8638126 8666229
APC CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
APC AXIN1 â—¼   PROTEIN_INTERACTION 26.0 1.0 ACSN 10421629 10581160 11487578 11955436 11967263 12051714 12554650 15001769 15327768 16039586 16288291 16940750 17143292 17318175 17936032 19619488 19751508 20006983 20705860 22270359 23343194 24023259 25730849 7542250 8638126 8666229
GSK3B APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 16944320 11166179 16799642 11967263 14663202 8524413 12554650 8638126 17910481 15327768 10581160 11487578 17318175 15465828 10228155 15020233 10421629 10698523 9832503
AXIN1 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16199882 20128690 19131971 11297546 9554852 22682247 10228155 26496610 23277359 10811618 9734785
APC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 10545404 11166179 8259519 7890674 22083140 27902311 8638126 16212417 16798748 19061640 9286858 15327769 9482734 11533658 22056988 19576224 15327768 17318191 26496610 12628243 15355978 9065403 11712088 25241761 26910375 22682247 9065401 12000790 11707392 20219694 9707618 23840886 15525529 11251183 8628279 19631635 11972058 21664290
E2F4 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20133863 21701264 17531812 17001309 20818429 17106239 23108140
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
E2F4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9244350 18319725 16713569 12909625
CDK2 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8764100 10373534 10550055 19683496 16713569 26719576 15212693
CDK1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9244350 21706030 10550055 17570479 19683496 16713569 26745677 32193285 26719576
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK1 PLK1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 7575488 9892021
TP53 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 10825186 11593387 12874009 19472317 10514438 11313928 16807237 8270002 17942917 9275177 20395210 11032828 19861536 12889596 19067706
E2F4 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15510213 17671431 11799067 11032828 17121828 17531812
GSK3B CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9832503 17359287
CCNA2 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 1833185 10924145 8423786
E2F4 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15510213 16135806
CDK1 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17764786 17660363 15279786 15917306
CDK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 24173284 12767922 1584757 20661218 26029996 2141171 9467949 17570479 20808790 7862459 11327730 11078726 27726420 8357826 16713569 2156209
CDK1 PRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 29484112 18691976 22621898 17351640 17438553 17512944 16603632 30992425 20633640 23940115 9885575 16964243 27551054 34158398
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
CDK1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21565170 27220480
CCNE1 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CCNA2 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK2 FZR1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10323868 10375532 16582612 12730199
E2F4 CDK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 22447046
CDK2 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21565170
CDK2 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 11598127 15577895 9736735 12560341 15558010 20068231 10548110 16123593 15840442 18669648
CDK2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 81.0 1.0 Omnipath 8756328 7553852 11377199 17145710 23602568 11983168 12044161 19483727 12853968 16209941 8397207 15455144 19631451 8475101 24358021 15557281 8684460 12941338 15647383 15890360 21447625 9380407 26496610 11141566 25852190 15189033 14656438 20733051 21241890 10652300 25669885 12244298 26186194 10930425 9660939 10477583 24302728 15239650 19773423 8463339 16290148 10924145 11907280 17361108 17254966 8662825 15828833 18471975 9724724 7630397 10559988 9716181 11940657 23455922
CDK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 24173284 9315650 19413330 19664995 16083285 1088347 16552184 10884347 17570479 10747897 25241761 7624134 11687964 17287340 92065884 12064478 19556892 14640983 10348343 14702041
CDK2 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 17145710 16223725 21092281 15004009 10962581 9840943 8643455 24358021 8861947 21372285 17570479 11237742 10330164 22558078 10652300 19561641 10477583 18691976 23853094 12144826 10500095 1388288 10827081 17970072 28137908 19470470 8756624 10809788 14536078 15364936
E2F4 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17531812 15105433 17981789
TP53 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17172872 17981789 15024021 22405092 20962589 24076372 23948487 15016801 22184120 19713933 16369493 23474762
PLK1 DCTN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21931181 28415805 23985322 23661607 20679239
PLK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22653443 19833129 16753148 23948487
PLK1 RACGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 28692064 17081983 16565220 27453045 19007248 19468300 25486482 19468302 19690332
PLK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20404109 16854412 26899266 19364923 25362646 20126263 12524548 26729093 11242082 12447691
SIRT6 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18337721 16439206 19408108
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
TP53 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16931621 8270002 9275177 19671680 16571800 8641461 9360984 21952947
TP53 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12874009 14627709 10051609 11313928 17942917 11892838 15710382 20395210 19470724 12379461 11071927 11522645 15737644 11162602
TTK TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19332559 27885363 23700430 22852086 23948487
GSK3B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23840442 12064478 11709713 9372954 11483158 16552184 17570479 14744935 16713569 21929745 12048243 21900206
CCNA2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14640983 10884347 16713569
E2F4 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 15855772 22508987
E2F4 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 17121828 21311680 15448153
GSK3B AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 102.0 1.0 Omnipath 20128690 16944320 11738041 20043192 12511557 11967263 16890161 22613765 14663202 23602568 8524413 24451375 19303846 12554650 8638126 22509369 18593713 16199882 21988832 23331499 19759537 10428961 9482734 22270359 19202075 17570479 16293724 15327768 10581160 17318191 11487578 22773187 26496610 16568235 17318175 19131971 15465828 26912724 25241761 24976009 21242974 22682247 10228155 23579495 12584189 23959799 15020233 10421629 10488109 11278246 9501208 18632848 10481074 10535959 10318824 9554852 17601533 9832503 21502811 9734785 23455922
AXIN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 20128690 20531388 16890161 27902311 22509369 18593713 16199882 23331499 9482734 21071413 26496610 19244247 22773187 17318191 10196136 18988627 17208333 19131971 24976009 22682247 10228155 12805222 12000790 10488109 9501208 9601641 18632848 9554852 19166851 23959799 12421363 9734785 11940574
RAC1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19751508 28626389 26403202 19417647 22270359 16212495 16940750 12480336 11152757 29497040 30650643 19020303 15377999
RHOA CIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8543060 12773565 17332740
TTK PRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12686615 14657364
KIF4A PRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23870126 15297875 15625105
GSK3B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 183.0 1.0 Omnipath 22415718 11967263 27158593 29455668 19303846 19797085 8638126 19293931 23056571 22662165 25352148 16611981 27068260 28337019 10671551 21743491 20688898 16293724 23721711 23552738 18687691 28977889 19622173 12051714 25241761 27683053 28549350 22699938 19565571 23076981 21562161 19575820 20219694 20537194 10330181 21986938 29183346 27773936 11251183 19711366 21035499 19675674 7542250 23151663 24451375 14663202 23804296 8524413 25639486 23770025 18070361 26892600 30143633 9233789 19667122 27507058 19061640 19223551 29387014 23331499 16199882 11533658 18644116 24501426 24913829 11835406 17318191 26014148 25366337 28183999 22640743 26910375 12000790 12114015 18387957 19107203 9832503 16371461 29805709 27462866 20137080 27902311 12040186 19576224 25644994 12615961 19060929 25897075 12851486 15465828 17053159 18952601 10228155 15020233 17444818 20140245 26453498 17052453 16944320 24015932 23602568 24975844 24931005 28948000 20080742 23209942 30271168 28220106 16520547 28430641 11818547 25546293 27672271 11955436 11154277 26373837 16039586 23778311 28697793 20302655 25136145 26905812 22216350 8666229 12957350 23109003 10074433 28529629 20215423 21329734 11254732 9501208 27098453 27281614 30279527 19631635 25482131 18455992 24403311 11274345
GSK3B CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 38.0 1.0 Omnipath 16944320 11967263 14663202 8524413 8861947 16039586 17570479 14536078 12615961 19561641 15465828 25241761 18691976 18319725 12459251 15020233 20537194 11124803 16131838 9832503 15364936
DNMT1 H3C2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C2 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170